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djeheuty-bros · 4 hours
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djeheuty-bros · 4 hours
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I think we ought to live happily ever after
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djeheuty-bros · 4 hours
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Heya guys. Sorry for posting this for the billionth time. But maybe if you guys would like to give my posts about patreon a boost it would mean the world to me. I know I post this a lot and I don't take any help I receive for granted. I've only been able to make two new drawings since February. Bc every day I have been working almost 9 hours. I'm sick nearly every other week, my lymph nodes are swollen n I've been feeling incredibly depressed. I am from the global south, in the philippines, government help is near nonexistent. I am the sole caretaker of three disabled people. My mom can not do any housework, she is a full time wheelchair user, she needs care 24/7, insulin, adult diapers and kidneys that are under threat of failing if we don't watch her health, my dad has a chronic heart condition and my sister is autistic with a very low frustration threshold. Both my parents are diabetic, and I am the only person in my family who can work. I currently have three jobs, one in publishing, but I have a morality clause which means the publishing house can take back every single penny I make if I or the author fail to meet certain expectations. Anyway.. I have been working nonstop, my scoliosis is untreated and extremely painful, n for the past few four days I have been rationing a single can of spam and a few potatoes. Would mean the world to me if you guys could pick up a print, or subscribe to my patreon, or reblog any of my old art or send me a tip on ko-fi or anywhere else. Sorry and thank you again. I remake these a lot, but I sincerely don't take any of the help I receive for granted. Thank you again.
My inprnt
My patreon
https://www.patreon.com/littlestpersimmon
My tipping jars
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djeheuty-bros · 4 hours
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I haven't purchased a HP item in close to a decade - I use the books I already had as doorstops or to prop a laptop up for meetings nowadays.
There is NO "death of the author" with JK Rowling - she controls and continues to profit from her IP, and uses that money to fund hate groups.
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djeheuty-bros · 5 hours
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the chocolate trigger thing is a myth??
Thank you for asking. The short of it is yes.
Chocolate as a posited migraine trigger came out of migraine journal studies. Basically, people suffering from migraine were asked to keep detailed journals of their lives, including what they ate, and this was compiled and trends were picked out.
One thing they found? People often ate chocolate before reporting a migraine attack.
There were two things going on here, though it took years for people to come to this conclusion. The first is that migraine prodrome can include sugar cravings-- so people who were already well on their way to a migraine attack were craving chocolate, ate the chocolate, and then reported the migraine. The second is that stress is a trigger of both migraines AND sugar cravings. Thus for someone had a rough week, the stress induced both a migraine attack and a desire for chocolate.
Later lab studies in which people who suffer migraine were given chocolate, or cocoa, or small doses of caffeine similar to what's found in chocolate, etc etc found that there was ZERO evidence for chocolate triggering a migraine. No component of chocolate triggered a migraine in sensitive people, even people who reported chocolate as a trigger.
So really, eating chocolate is a symptom of migraine, not a trigger of it.
These same food diary studies also led scientists to (briefly) believe that alcohol might PREVENT migraines. Why? People who reported fewer migraine attacks drank more alcohol. The actual finding here? People who have more migraine attacks don't frequently drink alcohol because jfc who wants a drink when they have a migraine (also migraine fucks up social lives). Alcohol, unlike chocolate, DOES trigger migraine attacks.
So these are the kinds of limitations of food diaries when you are trying to figure out what triggers your migraine attacks, and also why doctors emphasizing food triggers, especially chocolate, get a side eye from me.
That said, there is ample evidence that when people feel in control of their health, they tend to feel better. If you believe that chocolate triggers migraine attacks and you feel like limiting chocolate helps you, I'm not going to tell you to stop.
But if your doctor handed you a pamphlet with 20 year out of date information on migraines that included the idea that you had to stop eating chocolate and cheese (no evidence for cheese, either, eat your heart out), I'm here to say your doctor is at least 8 years out of date with the literature.
TLDR; chocolate fine, alcohol bad, doctors lazy, science progresses
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djeheuty-bros · 5 hours
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Photography 4 Humanity 2023 GLOBAL PRIZE
Recipient: Kristina Varaksina
Title: The Seashore is No Longer Here
Description: ”School girls stand in an abandoned seaport town next to an installation showing where the Aral Sea used to come."
Location: Karakalpakstan, Uzbekistan
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djeheuty-bros · 5 hours
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do not understand people who get bored of seeing common animals. understand even less when they act with annoyance or hostility just because they're common animals. a deer or a sparrow or a field mouse is like a sunset to me
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djeheuty-bros · 6 hours
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I don't see people talking about this so today is the 110th anniversary of the Triangle Shirtwaist Factory fire, in where the factory owners locked working women and girls inside to "eliminate the risk of theft" (in reality it was too keep them from taking breaks), which resulted in the gruesome deaths of 123 mostly immigrant women and girls and 23 men, many of whom jumped to their deaths from the ninth floor either in a panicked attempt to escape or in order to die quickly. There were reports that some of the workers were on fire already as they jumped.
The eighth floor of the building was able to telephone the tenth floor to warn them about the fire, but the factory on the ninth floor where these women and girls labored had no such communication and such warning.
The factory owners were criminally charged with manslaughter for actions that contributed to the mass deaths but acquitted. However, this tragedy led to mass sympathy to the labor movement, and unions spurred on safety regulations that passed in New York state and eventually the entire country, and activists were able to reduce child labor in the process.
This tragedy is a reminder that has been forgotten in the 110 years since: every safety regulation-- every scrap of paperwork contributing to the hundreds of pages of red tape people like to complain about--every word of it was written in the blood of a laborer.
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djeheuty-bros · 6 hours
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djeheuty-bros · 6 hours
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dicentra spectabilis ‘alba’  - bleeding heart.
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djeheuty-bros · 6 hours
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djeheuty-bros · 6 hours
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roman senator pussy got me acting impudicus et imprudenter
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djeheuty-bros · 6 hours
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“As a biologist, the terms biological woman and man don’t make any sense to me” okay then you’re an idiot and a terrible biologist. I swear to god, morons like you only become biologists just so you can hold it over others, when in reality, if biology deniers like you can become biologists, then being one really doesn’t mean much anyway. But this probably just gave an autogynophile like you a boner to read, anyway.
Oh fun! Haven't gotten one of these in a while. Disregarding the fact that you somehow think the qualification for being a biologist entirely hinges on defining womanhood, I do need to ask some clarification. I know I'm feeding the trolls here, but here we go: does your definition of "biological woman" mean:
Sociological woman? Eh, context dependent, I'm not fully out of the closet, but oftentimes, I am and present femme. So let's call that one 50/50.
Psychological woman? Because I am one.
Neurological woman? Because I am one [1].
Physical woman? My soft tissue redistribution is handling that well.
Hormonal woman? My blood tests are within cis female ranges.
Transcriptional woman? As a signalling molecule, the downstream effects of estrogen have broad transcriptional effects, completely changing the profile of gene expression and functional genomics of my cells. [2]
Genetic woman? I mean, see my above point- as far as my genes that are actually active, I have all of the same transcripts being produced, controlling which genes are expressed.
Karyotypic woman? I actually have a few signs pre-HRT that might point to a non-XY chromosome pair, but I haven't had a karyotype. We'll put that down as unknown. And hell, even if its XY, there's plenty of cis women who are karyotypically XY, with suppressed sry or complete androgen insensitivity. Interestingly enough, a completely androgen insesitive woman can go her whole life without knowing- and functionally, is very similar to a trans woman, actually. Fancy that. [3]
Reproductive woman? I can't produce an egg cell, but neither can significant fractions of cis women. Also, this is all gonna change soon, which is fun. [4]
There's also a lot of understudied aspects to the biology of HRT and even pre-HRT that are emerging, largely demonstrating widespread cellular and genetic remodeling of trans individuals undergoing hormone therapy. The field is a bit behind due to constant political pressure to revoke funding, but a lot of the results are extremely exciting in both testosterone and estrogen hormone therapies. I'm sure that, as a self professed biology As someone who presumably has a lot of expertise in biology, I'm assuming that you're aware of all of this cutting edge research, and are keeping up with modern papers, including but not limited to these cool findings:
Trans men on HRT exhibit significant genetic and transcriptional changes that make them biochemically male. [5][6]. It's a good hypothesis that the same happens with estrogen treatment, but those studies don't exist yet- I'm sure you're reserving judgment until more publications exist, of course.
Trans men on HRT develop male cell types and tissues. [7]
Trans women experience muscular and blood cell changes that align with cis women moreso than cis men [8]
And many, many more! This is an exciting, underserved, and groundbreaking field of research, and I'm sure you're keeping up with the latest in scientific journals about it.
I'm sure, of course, that you understand that it becomes impossible to draw a distinct line anywhere in here, and that words like "woman" are shorthand for the myriad of traits that invisibly synthesize in our mind and in society to represent a concept? I'm sure you understand that science is fundamentally descriptive, not prescriptive? I'm sure that you understand that these findings, while really cool and interesting, actually don't mean jack shit about what the word "woman" means or not?
As someone who is the ultimate decider in what a biologist is, I'm sure you know that bioessentiallism is a childish mindset that completely ignores and disregards the constantly changing, dynamic nature of biological systems, something that extends well beyond biological sex and its relation to gender.
I'm sure that also, that you understand that beyond just this, that the role of science in society is to advise how to achieve our moral principles, not create moral principles in themselves. And I'm sure that understanding means you know that trans affirming healthcare and supportive societal treatment leads to reduced mortality and increased happiness for everyone, right?
So great to talk to someone who is surely a scientist on this. You are a biologist, if you're talking like this, I assume? I assume you're not going to spit complete misreadings of scientific language from the background sections of these papers that only reveal you've never read a scientific paper in your life if you're thinking this way? I assume you have experience interpreting data like this?
Also, imagining my genitalia while writing this? Ew. Please stop projecting your fetishes into my inbox.
Works cited:
Kurth F, Gaser C, Sánchez FJ, Luders E. Brain Sex in Transgender Women Is Shifted towards Gender Identity. J Clin Med. 2022 Mar 13;11(6):1582. doi: 10.3390/jcm11061582. PMID: 35329908; PMCID: PMC8955456.
Fuentes N, Silveyra P. Estrogen receptor signaling mechanisms. Adv Protein Chem Struct Biol. 2019;116:135-170. doi: 10.1016/bs.apcsb.2019.01.001. Epub 2019 Feb 4. PMID: 31036290; PMCID: PMC6533072.
Gottlieb B, Trifiro MA. Androgen Insensitivity Syndrome. 1999 Mar 24 [Updated 2017 May 11]. In: Adam MP, Feldman J, Mirzaa GM, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2024. Available from: https://www.ncbi.nlm.nih.gov/books/NBK1429/
Murakami, K., Hamazaki, N., Hamada, N. et al. Generation of functional oocytes from male mice in vitro. Nature 615, 900–906 (2023). https://doi.org/10.1038/s41586-023-05834-x
Pallotti F, Senofonte G, Konstantinidou F, Di Chiano S, Faja F, Rizzo F, Cargnelutti F, Krausz C, Paoli D, Lenzi A, Stuppia L, Gatta V, Lombardo F. Epigenetic Effects of Gender-Affirming Hormone Treatment: A Pilot Study of the ESR2 Promoter's Methylation in AFAB People. Biomedicines. 2022 Feb 16;10(2):459. doi: 10.3390/biomedicines10020459. PMID: 35203670; PMCID: PMC8962414.
Florian Raths, Mehran Karimzadeh, Nathan Ing, Andrew Martinez, Yoona Yang, Ying Qu, Tian-Yu Lee, Brianna Mulligan, Suzanne Devkota, Wayne T. Tilley, Theresa E. Hickey, Bo Wang, Armando E. Giuliano, Shikha Bose, Hani Goodarzi, Edward C. Ray, Xiaojiang Cui, Simon R.V. Knott, The molecular consequences of androgen activity in the human breast, Cell Genomics, Volume 3, Issue 3, 2023, 100272, ISSN 2666-979X, https://doi.org/10.1016/j.xgen.2023.100272. (https://www.sciencedirect.com/science/article/pii/S2666979X23000320)
Xu R, Diamond DA, Borer JG, Estrada C, Yu R, Anderson WJ, Vargas SO. Prostatic metaplasia of the vagina in transmasculine individuals. World J Urol. 2022 Mar;40(3):849-855. doi: 10.1007/s00345-021-03907-y. Epub 2022 Jan 16. PMID: 35034167.
Harper J, O'Donnell E, Sorouri Khorashad B, McDermott H, Witcomb GL. How does hormone transition in transgender women change body composition, muscle strength and haemoglobin? Systematic review with a focus on the implications for sport participation. Br J Sports Med. 2021 Aug;55(15):865-872. doi: 10.1136/bjsports-2020-103106. Epub 2021 Mar 1. PMID: 33648944; PMCID: PMC8311086.
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djeheuty-bros · 6 hours
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genuinely inconsolable I can't have one of these pompeii bread plushies fr.
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djeheuty-bros · 6 hours
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The Bronx Zoo has just released Flaco's necropsy results.
He was not thriving, as the people championing the ideal of "freedom" claimed.
He was poisoned.
He was sick.
He was suffering.
"Freedom" would have eventually killed him. A building just happened to do it first.
"Postmortem testing has been completed for Flaco, the Eurasian eagle owl that was found down in the courtyard of a Manhattan building a little over a year after his enclosure at the Central Park Zoo was vandalized on February 2, 2023. Onlookers reported that Flaco had flown into a building on the Upper West Side of Manhattan on February 23, 2024, and acute trauma was found at necropsy. Bronx Zoo veterinary pathologists determined that in addition to the traumatic injuries, Flaco had two significant underlying conditions. He had a severe pigeon herpesvirus from eating feral pigeons that had become part of his diet, and exposure to four different anticoagulant rodenticides that are commonly used for rat control in New York City. These factors would have been debilitating and ultimately fatal, even without a traumatic injury, and may have predisposed him to flying into or falling from the building. The identified herpesvirus can be carried by healthy pigeons but may cause fatal disease in birds of prey including owls infected by eating pigeons. This virus has been previously found in New York City pigeons and owls. In Flaco’s case, the viral infection caused severe tissue damage and inflammation in many organs, including the spleen, liver, gastrointestinal tract, bone marrow, and brain.   No other contributing factors were identified through the extensive testing that was performed. Flaco’s severe illness and death are ultimately attributed to a combination of factors—infectious disease, toxin exposures, and traumatic injuries—that underscore the hazards faced by wild birds, especially in an urban setting."
The naturalistic fallacy kills animals in horrible ways. The romanticism of what humans want to think of as a "free, wild, pure life" cannot be allowed supplant the reality of injury, sickness, and death. Releasing captive animals (or keeping them from being recaptured) because it's "better" for them to suffer untethered than live a healthy, safe, captive life is inhumane and horrific.
Flaco's life didn't have to end in pain, sickness, and suffering.
Flaco's death didn't have to be tragic.
But once the idea of "freedom" entered the chat, Flaco's fate was unavoidable.
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djeheuty-bros · 6 hours
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djeheuty-bros · 6 hours
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Imperial passport of Kublai Khan “I am the emissary of the Khan. If you defy me, you die.” 1240 A.D. [886x960]
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