#INSERM | Explore Tumblr Posts and Blogs

twdmusicboxmystery · 10 months

Text

Daryl Dixon Sneak Peek, Part 3

@wdway:

Not necessarily in order but here's most of the scenery where Daryl is on his journey. The one I'm lacking is the one with some large ancient looking ruins. I'm not sure @galadrieljones, if you want to take that mission on, to find out where those ruins are. And I promise I will stop using you as my personal Google source. Anyway the thing that caught my attention from the shots I took was Daryl's legs walking on the railroad tracks.

It wasn't until I enlarged that I realized he has a large knife strap to his left leg.

@twdmusicboxmystery:

For me, just the fact that he's walking along rxr tracks is huge. It's a callback to S4 when he walked along them toward Terminus with Beth. (As well as a callback to Denise, but she was a Beth proxy anyway.)

@galadrieljones:

Château des Baux-de-Provence

The other one is more difficult

@galadrieljones:

The Meunerie Hydraulique de Barbegal came up a couple times, but I can't pinpoint it as a perfect match. It's basically a very old ruin of some Roman water mills. It's also very close to Marseille so I wouldn't be surprised if it was it.

Searching a couple angles I have also come up with Chaine de la Pene which means Rocks of the Pene and is in the Alps near Marseille, where the old water mills are located, so I think that’s probably where he is in the second photo here.

@wdway:

This is showing all the landmark being between Marseille and Lyon with an actual Level 4 Laboratory in the Lyon area. This is very exciting to me.

@galadrieljones:

Yeah, these are all in southern france

all like a day or two hike from marseille

Sorry these are the Pyranees lol

i get my french mountains mixed up actually. idk which they are. oh well

i love this kind of thing lol i should have been a detective

or like a behind the scenes detective like i don't want to walk around crime scenes no thanks!

I just went ahead and looked it up since it’s the only one that’s not french military

@wdway:

I've mentioned this a couple of times but seriously when you get a chance you need to check out the Southern Cross. Using the Southern Cross and the five star points is how people in the southern hemisphere find true Due South. Just as we use the Big Dipper to help locate the North Star. They've got to have a reason to want us to know about star constellation.

@galadrieljones:

Built and owned by Fondation Mérieux. The Mérieux family is an old business dynasty from Lyon. From wikipedia: “Marcel Mérieux (1870–1937), ESCIL student in 1891, former assistant to Pasteur, founder in 1897 of Mérieux Biological Institute in Lyon (origins of the Institut Mérieux holding) in 1897 (now part of Sanofi Pasteur). Just want to point out that he was a former assisten to Louis Pasteur, who discovered the principles of vaccination.

The Foundation Mérieux is operated by something called INSERM, aka the French National Institute of Health and Medical Research. It’s a major governmental organization which includes research laboratories and hospitals. It’s the “only public research institution solely focused on human health and medical research in France.” It is in Paris. This is a lot to say that the Lyon facility is actually much more interesting than it initially seemed.

If Daryl was lead to Lyon, then this connection could also lead him to Paris. The thing is ofc the intitutes they use will probably be “fictional”; however, not necessarily, and/or they could be like a mixture of fact and fiction, which TWD does a lot. The fact that the CDC/Atlanta and Galveston have both been major settings tells me they know what they’re doing, like they’re thinking about this stuff.

@galadrieljones:

Firstly, however, I looked more closely at the “Pouvoir Des Vivants” shot and this was interesting. You can see underneath the graffiti references to “Museum National d’Histoire Naturelle,” which is the Natural History Museum of France and is located in Paris.

They’re kind of jerking us all around, that’s what this tells me lol. Not sure why, but it seems like, whatever he’s looking for, probably it is ultimately in Paris. Whether he gets there via the Lyon connection i have no idea but there is interesting backstory here!

@wdway:

I'm going to be lazy and ask you for the translation again on this. This time I'll try to note it so I won't have to ask again.

@galadrieljones:

I think it means “Power of the Living” something like that

Our one clue as to what this place might be called:

@wdway:

Thank you for the translation. This kind of goes in hand with the dialogue in TWB. I'll have to go back and check out what the guy that are killing the scientist, what he said to the woman. This slogan sounds like it could be a slogan for them. The power of the living.

I'm thinking that the place that Daryl is shown at is not the Laboratory where the TWB women was, but it might be a place that they gathered away from the company that's possibly watching them. A place where the scientists could work together without worrying about a watchful eyes on them. Where they could openly talk about what was happening to their work and where it went wrong and how they could fix it.

If they're not feeling comfortable about where their research, their work is going with the company and how I'm thinking the military has stepped in and taken it over. That maybe Daryl found out that there might be some records kept at that location where some of the scientist had gathered. Where some of them have been pulled from and killed like the guy in the coda talked about. Daryl might think that there could still be records, video recordings to check out. Just a out there speculation on my part.

@galadrieljones:

I love it !

@twdmusicboxmystery

Something this made me think of. And my gut reaction is that it's not practical...but maybe it is. We keep asking how Carol is going to show up there, and I Think your idea about the two of them leaving and getting separated is very plausible. And even the symbolism works. The two of them left together at the beginning of Find Me, and then separated purposefully at the beginning of Diverged. So, it works.

But just to throw something else out there... What if Daryl just goes back and gets Carol? I know how implausible it sounds, but hear me out. In S5, rather than run back into the church, he and Carol jump in the car and follow the Grady car to Atlanta. When Carol is taken into the hospital, rather than try to rescue her and Beth on his own, he takes Noah and goes to get the others. Daryl is just smart enough and humble enough to recognize when he needs help and can't do something on his own.

And of course there are the logistics of getting back across the ocean. Twice. But in S5, he just found a vehicle that got him back to the church and then back to Atlanta quickly. He also did this in S6, taking the Paddy truck after Dwight and Sherry double crossed him. If he runs into the CRM, they may have really fast, reliable sea vehicles that he could take, and go get Carol to bring her back much more quickly than he himself ended up there.

Anyway, I know it's still implausible, but I"m just reaching back to earlier seasons and trying to use them as a template. You know, like I do. ;D

@galadrieljones:

I think it’s plausible. Or he might have had access to a long range radio and called for her to come. I was also thinking about Find Me. Remember how Carol tagged along uninvited. Maybe she follows him?

@twdmusicboxmystery

Yeah, good points. If she thinks he's in trouble, she'll go to him as well. Find Me and Diverged proved that.

@galadrieljones:

Personally I would hope that she is invited or I actually love the idea of him asking her for help. (The difference between a hardcore Bethyler and a hardcore Caryler is that I am not at all threatened by him having an adult friendship w Carol )

@twdmusicboxmystery

Same. Totally.

@wdway:

@twdmusicboxmystery, I actually love your idea about Daryl going back for Carol. It's actually what I was going to somewhat work on last night and was just hit with a mental block and had to crash. I could go into a bunch of history but I'll just cut to the chase and say that I think he/ they may leave from Charleston, NC or Savannah, GA coastline. I know the Commonwealth was using a nearby Charleston as a meeting place but when Daryl mentioned in s11 rumors of guns selling in Charleston I immediately thought of Charleston, North Carolina.

During the Civil War there was blockade gun runners and black markets. There also sites of pirates in both Charleston and Savannah and Carol did find the pirate book in Daryl's apartment. Both famous for kidnapping/Shanghai man to crew ships. Daryl wouldn't necessarily have to physically go back and get Carol since all those community sites have been torn down. I could see him using some type of radio in order to talk to her. Kind of like they use the radio between Oceanside and Alexandria.

So you can see I'm totally on board with your theory. Even if he contacted her and told her his plans and where he was headed and she was going to come after. They would set up a place to meet, they might go that route now that she's going to join him n s2.

@wdway:

By tomorrow we will all be on board with a new episode, I won't spoil anything or at least not too much but I'll just make the statement that I've enlarged the pictures. And I was like, oh my God! when I saw that scene. I was just blown away with all the Daryl and Beth call backs from 30 Days, Still and Alone. Negan's speech about hope was definitely a real work/call back of Beth's monologue in Inmates.

I said this earlier this afternoon but I really can't think of any other way but that Maggie or someone, possibly Daryl went back to the Greene's farmhouse. Maybe that's one of the places Daryl went during his year of being gone from the Commonwealth.

@galadrieljones:

I’ve got my eyes and ears open. Also that’s really interesting the note about Charleston during the Civil War. Do you meant Charleston, SC?

@wdway:

My bad. Yes, I'm talking about Charleston South Carolina. They're also just a lot of ships, cruise, cargo and even submarines. In Fear we saw that huge shipyard with all those shipping containers, you would need cargo ships to move move those and basic manpower.

#beth greene #beth greene lives #beth is alive #beth is coming #td theory #td theories #team delusional #team defiance #beth is almost here #bethyl

6 notes · View notes

buzzesante · 10 months

Text

RDKT : premier dispositif médical connecté pour accélérer la prise en charge des maladies rares

Pour combattre l’errance diagnostique des patients atteints de maladies rares, une nouvelle application web et mobile pour les professionnels de santé est désormais disponible : RDK (Rare Disease Knowledge). Découverte. Issue d’un partenariat public-privé unique qui s’appuie sur l’expertise d’Orphanet-Inserm, la technologie de Tekkare®, l’engagement sociétal de As We Know® et le soutien de…

View On WordPress

#application mobile santé #As We Know #digital santé #e-santé #esanté #Maladies rares #Orphanet #patient #Rare Disease Knowledge #RDK #sante 2.0 #Tekkare

3 notes · View notes

labioaulabo · 2 years

Text

Benoit Gachet, Ingénieur l’unité INSERM U1137 – IAME

Bonjour !

Je m’appelle Benoit Gachet. Après un master de recherche réalisé à l’Ecole Pratique des Hautes Etudes de Paris, j’ai intégré en tant qu’ingénieur l’unité INSERM U1137 – IAME (Infection, Antimicrobials, Modelling, Evolution) en 2018.

Le thème central de mon laboratoire de recherche est la bactérie Escherichia coli. Cette petite bébête est retrouvée de manière commensale (c’est-à-dire naturellement) et abondante dans notre tube digestif. Elle joue un rôle majeur dans de nombreux mécanismes biologiques et biochimiques chez nous autre les Hommes. Malheureusement Escherichia coli n’est pas qu’un ami qui nous veut du bien et certaines souches sont pathogènes pour l’Homme et vont induire des maladies qui vont du simple « dérangement intestinal » jusqu’à la septicémie voire le décès. De plus avec l’utilisation massive des antibiotiques (les antibiotiques, ce n’est plus automatique) il arrive qu’on ne dispose plus de traitement pour soigner des patients ayant une infection à Escherichia coli, c’est ce qu’on appelle une impasse thérapeutique.

C’est là que j’interviens grâce aux différents projets auxquels je participe. Nous essayons, avec mes collègues, de mieux comprendre cette bactérie essentielle pour nous. Mes projets vont de la recherche purement théorique, avec l’étude de l’évolution du génome d’Escherichia coli au cours du temps et dans différentes conditions de culture, jusqu’à des thématiques plus appliquées pour l’Homme avec des études sur l’antibiorésistance de certaines souches.

En dehors du travail, j’aime sortir avec mes amis, aller boire des verres entre collègues mais aussi voyager et suivre le sport de manière générale.

#bacteria #antibiotics

3 notes · View notes

entomoblog · 2 months

Text

Les bactéries, ces super-productrices de médicaments : La science à la pelle - Trouver des médicaments sous nos pieds

See on Scoop.it - Les Colocs du jardin

Pendant l’été 2022, chaque citoyen·ne a été invité·e à prendre part au projet et à recueillir et envoyer des échantillons de terre sur le territoire français (en métropole – voir la carte) afin d’identifier de nouvelles molécules issues des bactéries vivant dans les sols.

Aude Bernheim, chercheuse en microbiologie et en génétique, lauréate du prix du Collège de France pour les jeunes chercheuses et les jeunes chercheurs 2022

02/02/2023

"Les échantillons reçus sont en ce moment traités en laboratoire afin d’isoler les différentes bactéries et peut-être découvrir de nouveaux systèmes de défense chimiques ! A terme, l’objectif est de découvrir de nouveaux médicaments… Affaire à suivre."

-------

NDÉ

Suite

La science à la pelle. Trouver des médicaments sous nos pieds https://la-science-a-la-pelle.webflow.io/

"Un grand nombre des médicaments que nous utilisons pour lutter contre des pathogènes, des parasites ou encore des cancers, sont issus de molécules produites naturellement par les bactéries des sols. Pourtant, seulement une infime portion des ces bactéries ont été étudiées en laboratoire. ‍ Nous sommes une équipe de recherche au sein de l’unité INSERM 1284 à Paris. Nos méthodes de recherche innovantes permettent d’étudier à grande échelle ces bactéries, et d’identifier les molécules intéressantes qu’elles produisent. Mais pour cela, on a besoin de vous pour prélever une grande variété de sols français !‍ Votre mission sera de récolter des échantillons de sols divers, et de les envoyer à notre laboratoire afin que les bactéries qu’ils contiennent puissent être isolées et analysées. ‍[...]

Et qui sait, peut-être qu'on trouvera des nouveaux médicaments dans les jardins de votre commune ?

*Statistiques mises à jour le 7 juillet 2023 :‍ 238 participant.es 84 départements explorés 1430 échantillons

Résultats https://la-science-a-la-pelle.webflow.io/results

"... nous avons réuni plus de 1400 échantillons prélevés par près de 300 participants durant l’été 2022 ! L’un d’entre vous nous a même envoyé 42 échantillons ! De notre c��té, 15 scientifiques participants au projet se sont relayés pour analyser vos échantillons. Nous prévoyons de finir de tout analyser d’ici la fin de l’été mais voici déjà les premiers résultats : À partir des sols que nous avons pu analyser pour l’instant, nous avons isolé en moyenne 7 espèces d’Actinobactéries par échantillon de sol. Nous avons isolé plus de 6 000 bactéries différentes à partir des échantillons déjà analysés. Nous avons ensuite extrait l’ADN de chaque bactérie puis réalisé une amplification des gènes biosynthétiques (recettes d’antibiotiques) s’y trouvant grâce à une méthode de PCR. Les gènes amplifiés ont ensuite été séquencés et leurs séquences ont été comparées aux gènes responsables de la fabrication des antibiotiques connus. Si la séquence d’un gène ressemble beaucoup à celle d’un gène connu, on en déduit que ce gène produit sans doute le même antibiotique. Si au contraire la séquence est très différente, il s’agit d’une séquence encore inconnue à la science, qui pourrait potentiellement fabriquer un nouvel antibiotique."

(...)

[Image] Capture d'écran

Bernadette Cassel's insight:

Scoop en relation

Aude Bernheim : Immunité bactérienne. À la découverte d'un nouveau monde - De www.youtube.com - Aujourd'hui, 17:25

0 notes

michaladamski1987 · 2 months

Text

Chi Collagen Elixir spakowany w złotą saszetkę wyposażono w dwa dodatkowe składniki w postaci soku z aceroli i soku z cytryny. Acerola i cytryna tworzą idealny duet stanowiący bogactwo naturalnej witaminy C. Ta z kolei jest niezwykle ważna w prawidłowej syntezie kolagenu.

Chi Elixir jest dla Ciebie, jeśli jesteś wymagający, cenisz walory smakowe i estetyczne oraz skuteczność produktu, po który sięgasz.

Kolagen zawarty w produktach Chi został poddany badaniom klinicznym w laboratorium dermatologicznym przy szpitalu w Nicei (CPCAD) oraz przebadany m.in. przez Państwowy Instytut Zdrowia i Badań Medycznych w Paryżu (INSERM).

Wasze zdrowie! 🥰

#uroda #prezentpr #współpracapr #chi #elixir #chielixir @chielixir #chioflove #chicollagen #chicollagenelixir #collagen #kolagen #kolagendopicia #kolagenwpłynie #kolagenrybi #peptydy #peptydykolagenurybiego #beautybloger #polskichłopak #polskichlopak #polishboy #polishguy #waszezdrowie

0 notes

stevelucienrodrigue · 3 months

Text

=Alzheimer’s: Sleeping Beauty=

The origin of the problem

When we wake up in the middle of the night, we can only remember the last few seconds of our dream. For those suffering from Alzheimer’s, their disturbed sleep cycle of six hours or less doesn’t end every morning. This causes residues of the sleep-regulating hormone melatonin to remain in the brain. So, while awake, the memory recalls only a few seconds of the events of the past hour, as if in a distant dream.

Backed by Science

Recent studies show that 8 hours’ continuous sleep reduces Alzheimer’s symptoms by 25%. Scientists also agree that cataracts cause sleep deprivation, as it’s mainly through the eyes that the brain evaluates bedtime (dark) and wake-up time (light). It’s a well-known fact that, from the age of 65 onwards, our eyesight declines, which corresponds to the onset of Alzheimer’s disease.

Solution Alpha: Vision and Hearing

For the body’s day evaluator to be effective, it’s important to have well-fitting glasses for 20/20 vision. Hearing, too, allows us to tell from birdsong and neighbourhood noises that morning has arrived. It’s a good idea to have a hearing aid with you when you sleep.

The Bedroom

A bedroom with curtains that let in light is detrimental to full sleep in spring and summer in the northern hemisphere, due to prolonged sunshine in these seasons. And the noises of the city and of nature, which come to life when the sun rises at 4 a.m., are equally problematic for our aging parents.

Solution Beta: Clean Sleep

Our mother will therefore need to sleep in a dark room away from surrounding noise from 10 p.m. to 6 a.m. Low-volume waves or rain music will help Mom sleep. And for waking, a lamp with a subdued colour and a loudspeaker with a gentle meditation melody, both programmed to activate at 6 a.m., will set the pace for melatonin to be successfully purged in the morning.

Alzheimer: Constance

It’s important to respect the same sleep schedule for weekdays and weekends as for children. Husbands should honour their wives’ rest cycles, or sleep in another room. A bedroom temperature of 20° Celsius (68°F) should be maintained.

And with this sleep-wake method, Alzheimer’s symptoms will diminish over the months: 25%, 27%, 29%, 31% up to vivid memory. “Good morning Mom! I’ll be waiting for you in the kitchen with your favourite tea and two slices of delicious blueberry toast.”

Source: Wikipedia, Inserm France, ma santé FACILE.

Text by Steve Lucien Rodrigue = Version 1.0 = Quebec CITY - CANADA = January 18th, 2024.

#alzheimer #sleep #vision #audition #science #medecine #melatonin #bedroom #glasses #wisdom #education #knowledge

0 notes