#June 19 2019

[warmglowofsurvival]

#twenty one pilots #twentyonepilots #josh dun #joshua dun #tyler joseph #2019 #june #june 2019 #june ‘19 #columbus #cbus #ohio #columbus oh #columbus ohio #saxx #saxx underwear #dave and jimmy #interview

[wiiildflowerrr]

'Johnny' Daigo Yamashita: 'No way!! My comb is featured on GQ magazine. I’m really happy you like it Ashton! Arigato🙏 @Ashton5SOS

5SOSのアシュトンが俺のコームを愛用してくれてるよ！嬉しいネ！ありがとう!'

19 June 2019

#this day in 5sos history #5sos #ashton irwin #5 seconds of summer #ashton 5sos #ashton #john #johnny pandora #comb #rockabilly!ashton #5sos japan #youngblood mv #gq 10 things #19 june #2019 #daigo yamashita

[world-of-wales]

CATHERINE'S STYLE FILES - 2019

11 JUNE 2019 || The Duchess of Cambridge carried out a series of engagements in Cumbria along with Prince William.

#duchess of cambridge #catherine cambridge #mine. #11.06.2019 #cumbria visit june 19 #british royal family #british royals #brf #british royalty #kate middleton #catherine middleton #royalty #royals #royal #royal fashion #fashion #style #catherines style files #style files 2019 #troy london. #fjallraven. #sézane. #chloé. #kiki mcdonough. #lauren gold pavé diamond leaf earrings #ballon bleu de cartier watch #cartier. #deepdale hall farm visit 19 #ullswater way nature walk 19 #keswick market 19

[alyandajsource]

iamaly: @bixbyofthehouseofblackandwhite supports equality so you should too! 🌈

#aly michalka #social media #2019 #june 19 #aly #aly sm

[followyourarrows]

June 19, 2019

#kacey musgraves #social media #2019 #june 19

[disneychannelhistory]

Today in Disney Channel History...

Amphibia season 1, episode 3A “Hop Luck” and season 1, episode 3B “Stakeout” premiered on Disney Channel (19 June, 2019)

#amphibia #disney channel #episode #19 june #june #2019 #june 2019

[littlemixdaily]

June 19, 2019

#jade thirlwall #leigh anne pinnock #social media #2019 #june 19 #jade x leigh anne #jade sm

[ellie-gouldings]

elliegoulding: Beautiful make up by @ lucylovebird for a video shoot so did a thousand selfies before removing (this is normal, right? 🥴 (and hair by @ panosphair) 👀

#ellie goulding #social media #2019 #june 19

[isupportzaynxliamxziam]

Wednesday, 19 June 2019

Being in England, Liam attends day 2 of Royal Ascot at Ascot Racecourse

He's there to support Special Effects, the UK-based charity, that's levelling the playing field for gamers with physical disabilities around the world. Steve Neal's very happy with Liam's help and posts about it on Twitter

At the event, Liam poses with a lot of people like ex Pro Footballer and Sports Presenter Ady Williams, who posts about it on Twitter

With his manager Steve Finnan and Simon Oliveira, Managing Director of Kin Partners, Liam poses, so he can post on his Instagram

Liam also poses with some fans, who also post about it on Twitter

Athete Denise Lewis also poses with Liam and Chief Commercial Officer Juliet Slot to post it on her Instagram

Once inside he poses once again

Educator and Editor Lena Lee also poses with Liam, to post it on her Instagram

credits to liam93videos / liam-93-productions

#Wednesday 19 June 2019 #Liam Payne #Day 2 of Royal Ascot #Ascot - England #Special Effects

[prokopetz]

This is your yearly reminder that Garfield the cat's birthday is not, in fact, June 19th. Though the comic titled Garfield debuted on June 19, 1978, the character himself first appears in an earlier comic by Jim Davis called Jon, which debuted on January 8, 1976. For reasons known only to himself, until around 2019 Jim Davis entirely disclaimed the existence of Jon, to the point that his official biographies make no mention of it and falsely give the 1978 date as Garfield's first published appearance. Garfield's real birthday is January 8th.

#media #comics #garfield #jim davis #history #media history

[mariacallous]

Updated vaccines against Covid-19 are coming, just as hospitalizations and deaths due to the virus are steadily ticking up again.

Today, the US Food and Drug Administration authorized new mRNA booster shots from Moderna and Pfizer, and a panel of outside experts that advises the Centers for Disease Control and Prevention voted to recommend the shots to everyone in the United States ages 6 months and older. Once Centers for Disease Control and Prevention director Mandy Cohen signs off on the recommendations and the vaccines are shipped, people can start getting the boosters.

The recommendation is projected to prevent about 400,000 hospitalizations and 40,000 deaths over the next two years, according to data presented at the meeting by CDC epidemiologist Megan Wallace.

This year’s mRNA vaccines are different from the 2022 booster in a key way. Last year’s shot was a bivalent vaccine, meaning it covered two variants: the original one that emerged in China in 2019, plus the Omicron subvariant BA.5, which was circulating during much of 2022. This fall’s booster drops the original variant, which is no longer circulating and is unlikely to return. It targets just the Omicron subvariant XBB.1.5, which was dominant throughout much of 2023.

Pfizer and Moderna’s vaccines work by introducing a tiny piece of genetic material called messenger RNA, or mRNA, that carries instructions for making SARS-CoV-2’s characteristic spike protein. Once it is injected, cells in the body use those instructions to temporarily make the spike protein. The immune system recognizes the protein as foreign and generates antibodies against it. Those antibodies stick around so that if they encounter that foreign invader again, they will mount a response against it.

Since the start of the Covid-19 pandemic, the virus has acquired new mutations in its spike protein and elsewhere. These mutations result in new variants and subvariants that diverge from the original virus. When enough mutations accumulate, these new versions can more easily evade the antibodies created by previous vaccine doses or infections.

The constantly evolving nature of the virus is the reason health regulators decided last year to update the original mRNA vaccines, which were designed against the version of the virus that first appeared in 2019. This year, once again, the virus has changed enough to warrant an updated booster.

In June, an advisory committee to the FDA recommended that this fall’s booster be a monovalent vaccine—targeting only the then-dominant XBB.1.5 subvariant.

At that meeting, committee members reviewed evidence suggesting that the inclusion of the original variant may hamper the booster’s effectiveness against newer offshoots. “The previous bivalent vaccine contained the ancestral spike and thus skewed immune responses to the old spike,” says David Ho, a professor of microbiology at Columbia University whose research, which is not yet peer-reviewed, was among the evidence the FDA panel reviewed. “This is what we call immunological imprinting, and it results in lack of immune responses to the new spike.” He thinks taking out the old variant should optimize the immune response.

But over the past few months, even newer Omicron offshoots have arrived. Currently, EG.5.1, or Eris, is the dominant one in the United States, United Kingdom, and China. Meanwhile, a variant called BA.2.86, or Pirola, has been detected in several countries. Pirola has raised alarm bells because it has more than 30 new mutations compared to XBB.1.5.

Even though the new boosters were formulated against XBB.1.5, they’re still expected to provide protection against these new variants. “The reason is, while antibodies are important in protection against mild disease, the critical part of the immune response that’s important for protecting against severe disease is T cells,” says Paul Offit, a professor of vaccinology at the University of Pennsylvania and member of the FDA’s vaccine advisory committee.

These cells are a different part of the immune response. Unlike antibodies, which neutralize a pathogen by preventing it from infecting cells, T cells work by eliminating the cells that have already been invaded and boosting creation of more antibodies. Both the Moderna and Pfizer-BioNTech Covid vaccines produce long-lasting T cells in addition to antibodies.

It’s why, Offit says, when the Omicron wave hit in late 2021 and peaked in January 2022, the US didn’t see a dramatic increase in hospitalizations and deaths even as cases rose significantly: People’s T cells kicked into gear, even when their antibodies didn’t recognize the Omicron variant.

“In some ways,” says Offit, when it comes to vaccine booster development, “it almost doesn’t matter what we pick to target” because the coronavirus has yet to evolve away from T cell recognition. “Everything works.”

Scientists think T cells are able to protect against severe Covid because they’re recognizing parts of the virus that have remained unchanged throughout the pandemic. “I suspect that as we continue to vaccinate, there are some conserved regions [of the virus],” says Jacqueline Miller, Moderna’s head of infectious diseases. “So even with the accumulation of mutations, we’re still building on previous immunity.”

People who have hybrid immunity—that is, have had a Covid infection and have also been vaccinated—seem to have the best immune responses to new variants, she says, which suggests that previous exposure shapes and improves immune responses to new variants. Preliminary studies show that antibodies generated by previous infections and vaccinations should be capable of neutralizing Pirola.

Earlier this month, Moderna issued a press release saying that clinical trial data showed that its updated booster generated a strong immune response against Pirola, as well as the more prevalent Eris variant.

In a statement to WIRED, Pfizer spokesperson Jerica Pitts said the company continues to closely monitor emerging variants and conduct tests of its updated monovalent booster against them. Data presented at Tuesday’s CDC meeting showed that Pfizer-BioNTech’s updated booster elicited a strong neutralizing antibody response against both Eris and Pirola.

The FDA expects that Covid-19 vaccines will continue to be updated on an annual basis, unless a completely new variant emerges that requires a different approach. “We will always be a little behind the virus,” says Ho. “In this instance, we won’t suffer too much, but that might not be the case going forward. Surveillance is imperative.”

[warmglowofsurvival]

#twenty one pilots #twentyonepilots #josh dun #joshua dun #tyler joseph #2019 #jordan dun #jordancdun #instagram story #june #june 14 #june 2019 #june ‘19 #jacksonville #beach #florida

[anyab]

Via NasAlSudan

December 17 2023. #KeepEyesOnSudan #SudanActionWeek

Swipe through to build a foundational understanding of the war, its origins, and the key players involved. For actionable ways to support those in Sudan, check the link in our bio. Stay tuned for more posts this week.

Transcript:

National:

On April 15, a war broke out in Sudan's capital city of Khartoum between the Sudanese Armed Forces (SAF), and a paramilitary group known as the Rapid Support Forces (RSF).

Since then, eight months of conflict has led to major destruction of Khartoum's infrastructure, the most developed region of Sudan, with fighting also spreading to the regions of Darfur in the west and Kordofan in the south.

Civilians in conflict zones have been forcibly displaced, under threat of physical and sexual violence, particularly by the RSF, which has looted, destroyed, and settled in people's homes.

Regional:

In the western region of Darfur, a campaign of ethnic cleansing is being carried out by the RSF targeting the Masalit tribe. Allegations of genocide have been levied against the RSF.

Reports have just emerged that fighting has now spread to Wad Madani in Al Gezira state, which houses nearly 500,000 IDPs from Khartoum.

Key figures:

Abdel Fattah al Burhan Head of SAF

Omar El-Bashir Deposed Dictator of Sudan

Mohamed Dagalo (Hemidti) Head of RSF

Transcript:

Sudan: the war in numbers

A humanitarian "catastrophe"

24.7 million in need of critical humanitarian assistance

70-80% of hospitals out of service in conflict areas

19 million children are out of school

20.3 million people acutely food insecure. 4.9 million facing emergency hunger levels

6.7 million displaced [5.4 million IDPS, 1.3 million refugees]

7,000+ cholera cases an increase of +136% over the past month

Transcript:

FAQ - THE SAF

QUESTION 01: What is the SAF?

Stands for the Sudanese Armed Forces

Is the de-facto government of Sudan

Is headed by Lt. General Abdel Fattah al-Burhan

QUESTION 02 What is their capacity?

Estimated to have ~200,000 personnel and tactical advantage of airforce

Currently control the relative northern and eastern regions of Sudan with functioning capital in Port Sudan (East)

QUESTION 03 Do they have backing and support?

On the international stage, primarily backed by Egypt

Limited weapons supply from allies

Internally, the SAF is ultimately considered the lesser of two evils

Transcript:

FAQ - THE RSF

QUESTION 01 What is the RSF?

Stands for the Rapid Support Forces

Paramilitary group originating from the Janjaweed, Arab tribal militias armed by al-Bashir in 2003 to fight against ethnically African rebel groups in Darfur + carried out 2003 genocide

Is headed by General Mohamed Hamdan Dagalo (Hemidti)

QUESTION 02 What is their capacity?

Estimated to have 100,000 to 150,000 troops

Winning the ground fight in Khartoum and control 4/5 states in Darfur

QUESTION 03 Do they have backing and support?

On the international stage, primarily backed by the UAE

Have steady weapons supply chain and diversified financial profile with critical assets in UAE and Russia

Transcript:

THE WAR IN SUDAN: CONTEXTUALIZING APRIL 15

(6/1989 - 4/2019) THE BASHIR REGIME

Sudan was under the rule of military dictator Omar Al-Bashir for 30 years, who came to power through an military coup backed by Islamist factions in June of 1989

His time in power was marked by extreme repression, conflict, and economic decline

(12/2018 CURRENT) THE REVOLUTION

In December of 2018, a popular democratic revolution began that eventually unseated al-Bashir on April 11 through the revolt of security sector

Al-Bashir was ultimately replaced by al-Burhan, with Hemidti as his deputy of a Transitional Military Council

Protestors rejected military rule and continued to hold a sit-in outside the military headquarters until its violent dispersal on June 3 of 2019 by the SAF + RSF

Today, the Sudanese people still hope and advocate for freedom from military rule and the transition to democracy

(8/2019-10/2021) TRANSITIONAL GOVERNMENT

Agreement on transitional government signed between civilian forces and Transitional Military Council on August 17, 2019

Led to formation of joint sovereign council with Abdalla Hamdok as Prime Minister

Transcript:

(10/2021 CURRENT)THE OCT 25, 2021 COUP

Burhan and Hemidti carry out military coup overthrowing civilian counterparts

They draw power from international legitimization despite prolonged mass protests in Sudan

(12/2022) THE FRAMEWORK AGREEMENT

In December of 2022, civilians put out a framework agreement signed onto by SAF and RSF + civil society groups and political parties meant to return to a transitional government

Key part of agreement: question of integration of the RSF into the SAF

Parties were to finalize the agreement and sign on April 1; RSF and SAF ultimately disagreed on integration timeline with RSF wanting 10 years and the SAF wanting 2

(12/2022-4/2023) THE LEAD UP TO APRIL 15

As framework agreement negotiations failed, both parties began mobilizing troops in capital of Khartoum in days leading up to April 15

Residents of Khartoum awoke to the sounds of gunfire on April 15 and by noon, the RSF had seized Meroe airport in the Northern state

Conflict today considered a battle for power between the two generals they are too far in to walk back

Transcript:

FRAMING ALLIANCES

Sudanese Armed Forces (SAF):

Egypt

Israel (Foreign Ministry)

Islamists

Iran

Saudi Arabia

Ukraine (SOF)

Armed Groups

Rebel groups that had taken up arms against the central government in the Bashir Era are forced to ally with the SAF due to the RSF's ethnic cleansing campaign. They include:

Justice and Equality Movement (Gibril Ibrahim)

Sudan Liberation Movement/Army (Minni Minawi)

Gathering of Sudan Liberation Forces (Abdallah Yahya)

Rapid Support Forces (RSF):

Israel (Mossad)

Libya (Khalifa Haftar)

United Arab Emirates

Central African Republic

Russia (Wagner Group)

Chad

Arab Tribal Leaders

Arab tribal leaders across the Western region of Darfur have pledged their allegiance and support to the RSF, with members of the tribes across the Sahel crossing into Sudan to join the RSF's assault as well.

Key tribes include: Beni Halba, Tarjam, Habaniya, Fallata, Misseriya, Taaysha, Rizeigat

Transcript:

IS THERE AN END IN SIGHT?

THE STATE OF NEGOTIATIONS

Effort: JEDDAH TALKS [MAY]

Parties involved: Externally: United States, Saudi Arabia Internally: SAF, RSF

Outcome: Discussed humanitarian ceasefire; signed Jeddah Declaration of Commitment to Protect the Civilians of Sudan - Failed

Effort: INTERGOVERNMENTAL AUTHORITY ON DEVELOPMENT (IGAD) [JULY]

Parties Involved: Externally: Kenya, Ethiopia, Djibouti, South Sudan Internally: RSF

Outcome: Proposed peacekeeping troops to ensure humanitarian corridor - Rejected

Effort: CAIRO TALKS (NEIGHBORING COUNTRIES) [JULY]

Parties Involved: Externally: Egypt, Ethiopia, South Sudan, Chad, Eritrea, CAR, Libya Internally: SAF, RSF

Outcome: Discussed lasting ceasefire, safe humanitarian passage, political dialogue framework - Failed

Effort: JEDDAH TALKS [OCTOBER]

Parties Involved: Externally: United States, Saudi Arabia Internally: SAF, RSF

Outcome: Discussed lasting ceasefire, safe humanitarian passage, political dialogue framework - Failed

Effort: IGAD + AFRICAN UNION (AU) [DECEMBER]

Parties Involved: Externally: IGAD, EU, UAE, Saudi Arabia, South Africa, United States Internally: SAF (Burhan in person), RSF

Outcome: Agreed to a face-to-face meeting in late December and ceasefire; SAF later issued a retraction - Ongoing

Transcript:

The conflict in Sudan calls for the collective support of all to raise awareness about the war and aid the Sudanese people on the ground, especially when we live in nations that have been complicit in the oppression of the Sudanese people. Explore the options below and share with others. For more information, check the link in our bio.

WHAT CAN YOU DO?

EDUCATE YOURSELF

Deepen your knowledge about Sudan, empowering yourself with insights into the complexities of the situation.

DONATE

Extend a helping hand to Sudan by generously donating to individuals or grassroots organizations on the ground.

CONTACT YOUR REPS.

Amplify your impact by contacting your representatives, advocating for positive change.

#sudan #keep eyes on sudan #KeepEyesOnSudan #Sudan Action Week #SudanActionWeek #i hope the way i formatted it is good #i saw a few hours ago that rsf retreated from wad madani outskirts

[minotaurmutual]

Star Wars: Knights of the Old Republic II: The Sith Lords / Lara Williams, Supper Club / Théodore Géricaul, The Raft of the Medusa (1818–19) / Jenefer Shute, Life-Size / Ovid (tr. Henry T. Riley), The Story of Erysichthon from Metamorphoses / Guillermo Lorca Garcia-Huidobro, The Banquet (2013-14) / Maya C. Popa, from “The Color Wheel Has Been Cancelled”, American Faith / Haruki Murakami, Norwegian Wood / Interview With the Vampire (1994) / Yves Olade, Belovéd / Natalie Diaz, Postcolonial Love Poem / William-Adolphe Bouguereau, Dante and Virgil (1850) / J. Karl Bogartte, A Curious Night for a Double Eclipse / Leah Raeder, Black Iris / Hannibal (2013-2015) / Marina Tsvetaeva, Poem of the End / The Terror (2018) / CS Lewis, The Horse and His Boy / Beastars (2019 - ?) / Hélène Cixous from “The Love of the Wolf” / “The Cannibal” / Azra T. / Raw (2016) / Richard Siken, from Crush; “Wishbone” / Severance (2022 - ?) / Emma Rebholz, No Good Boodsuckers / Aex Lemon, Another Last Day / Francisco Goya, Saturn Devouring His Son (c. 1819–1823) / Anne Carson, Plainwater: Essays and Poetry / Black Sails (2014 - 2017) / Kathy Acker, Empire of the Senseless / Anaïs Nin, Henry and June / Neon Genesis Evangelion (1995–1996) / Tanaka Mhishi / Margaret Atwood, You Are Happy / Jennifer’s Body (2009) / KotOR II / Edna St. Vincent Millay, from The Collected Poems of E. M; “True Encounter”

#hi it was time for one of these again <3 #hunger #cannibalism #interview with the vampire #hannibal #raw 2016 #severance #black sails #neon genesis evangelion #nge #jennifer's body #the terror #beastars #kotor #kotor 2 #star wars #webweaving #intertextuality #comparatives #op #*

[alyandajsource]

iamaly: Thank you Dallas! What a night to remember...especially dedicating one of @auhasardspr favorite @thenational songs to him on our 4 year wedding anniversary 💍 📷 @kristinaskool #ineedmygirl

#aly michalka #social media #2019 #june 19 #aly #aly sm

[followyourarrows]

June 19, 2019

#kacey musgraves #social media #2019 #june 19