#claudication

[mcatmemoranda]

The most effective medication for intermittent claudication in patients with peripheral artery disease (PAD) is cilostazol, a phosphodiesterase 3 inhibitor. This leads to inhibition of platelet aggregation and vasodilation through increased cyclic AMP.

Rest pain is concerning for critical limb ischemia. Common co-morbid conditions include diabetes, hypertension, and hyperlipidemia. Common examination findings are indicative of poor arterial circulation to the extremities, including pallor, loss of hair, and diminished pulses. First-line medical treatment for intermittent claudication caused by PAD is cilostazol, a medication that inhibits phosphodiesterase 3, leading to relaxation of vascular smooth muscles.

First-line treatment without pharmacotherapy for intermittent claudication includes multiple lifestyle modifications. Measures for prevention may include smoking cessation, blood pressure control, anti-lipid therapy, weight loss, and the initiation of an exercise program. If an exercise program fails or causes additional pain, pharmacotherapy may be indicated. If pharmacotherapy fails, patients may be a candidate for more invasive interventions by a vascular surgeon depending on the degree and location of obstructed flow.

#PAD #cilostazol #claudication

[vascular-surgeon-azeemagha]

#vascular surgeon pakistan #vascular surgeon islamabad #best surgeon #surgeonazeemagha #surgeon azeem agha #vascular surgery services #islamabad #pakistan #diabetic foot ulcer #diabetic #diabetic foot treatment #vascular access #kidney dialysis #hemodialysis and peritoneal dialysis market #dialysis fistula #varicose veins #varicoseveintreatment #vascular surgery #surgery #abdominal aortic aneurysm #aortic stenosis #aortic dissection #leg pain #claudication #leg swelling #dilated veins #artery #veins #sexualwellness #erectile dysfunction

[phonemantra-blog]

Peripheral Vascular Disease (PVD): Causes, Symptoms, and Treatment Peripheral Vascular Disease (PVD) is a significant health concern affecting millions worldwide. This article aims to provide a comprehensive understanding of PVD, covering its causes, symptoms, diagnosis, and treatment options. We'll delve into the importance of early detection and management, equipping you with essential knowledge for a healthier life. Understanding PVD: A Closer Look Peripheral Vascular Disease, commonly referred to as PVD, encompasses a range of conditions that affect the blood vessels outside the heart and brain. At its core, PVD is primarily caused by atherosclerosis, a process where arteries become narrowed and hardened due to the buildup of plaque. Types of PVD PVD isn't a one-size-fits-all condition; it manifests in various forms, with the most common being Peripheral Arterial Disease (PAD) and venous PVD. PAD results from narrowed arteries, reducing blood flow to the limbs, while venous PVD involves issues with the veins, often leading to blood pooling in the legs. Symptoms of PVD Recognizing the Telltale Signs Identifying the symptoms of PVD is pivotal for timely intervention. Here are some common indicators to watch out for: Leg Pain or Cramping: Individuals with PVD often experience pain, cramping, or aching in the legs, particularly during physical activity. Numbness or Weakness: Numbness, weakness, or a feeling of heaviness in the legs can be early signs of compromised blood flow. Coldness in Extremities: Persistent coldness in the hands or feet may indicate poor circulation. Skin Discoloration: Changes in skin color, such as paleness or blueness, can be attributed to reduced blood flow. Risk Factors Unveiling the Contributors to PVD Understanding the risk factors associated with PVD is essential for proactive health management. Here are key factors that can increase your susceptibility: Smoking: Smoking remains one of the most significant contributors to PVD, accelerating the hardening of arteries. Diabetes: Individuals with diabetes are at higher risk due to potential damage to blood vessels. High Blood Pressure: Hypertension strains blood vessels, making them more susceptible to PVD. High Cholesterol: Elevated cholesterol levels contribute to plaque buildup, a primary PVD trigger. Diagnosis and Evaluation Crucial Steps in Identifying PVD Timely diagnosis is paramount in managing PVD effectively. Healthcare professionals employ various methods to evaluate and diagnose PVD. Here's a glimpse into the diagnostic process: Ankle-Brachial Index (ABI) Test: ABI is a non-invasive test that measures blood pressure in the arms and ankles, aiding in the assessment of blood flow. Doppler Ultrasound: This imaging technique uses sound waves to create images of blood flow within the arteries, helping identify blockages. Angiography: Invasive angiography involves injecting contrast dye into the arteries to visualize blood flow and pinpoint areas of concern. Treatment Options Navigating the Path to Wellness The management of PVD involves a spectrum of treatment options tailored to individual needs. Here's an overview of strategies aimed at improving circulation and enhancing well-being: Lifestyle Changes: Embracing a heart-healthy lifestyle through balanced nutrition, regular exercise, and smoking cessation can significantly mitigate PVD progression. Medications: Physicians may prescribe medications such as antiplatelet drugs and statins to manage risk factors and improve blood flow. Minimally Invasive Procedures: Interventions like angioplasty and stenting can effectively open narrowed arteries, restoring proper blood flow. Surgical Interventions: In severe cases, bypass surgery may be necessary to reroute blood around severely blocked arteries. Living with PVD Empowering a Fulfilling Life Living with PVD necessitates adjustments and strategies to ensure a fulfilling life. Here, we'll explore practical tips and insights for individuals managing PVD, including: Pain Management: Techniques for addressing leg pain and discomfort. Mobility: Tips for maintaining mobility and staying active despite PVD. Support and Resources: Information on support groups and resources available for those with PVD. Prevention Guarding Against PVD Prevention is a powerful tool in the fight against PVD. We'll delve into proactive measures individuals can take to reduce their risk, including: Healthy Eating: Dietary choices that support vascular health. Physical Activity: The role of exercise in maintaining circulation. Regular Check-Ups: The importance of routine medical assessments.   frequently asked questions (FAQs) related to Peripheral Vascular Disease (PVD) along with their answers, formatted in Markdown: Q1: What is Peripheral Vascular Disease (PVD)? Peripheral Vascular Disease, often abbreviated as PVD, refers to a group of conditions that affect the blood vessels outside the heart and brain. It typically involves the narrowing or blockage of blood vessels, which can lead to reduced blood flow to the limbs. Q2: What are the common symptoms of PVD? Common symptoms of PVD include leg pain or cramping, numbness or weakness in the legs, coldness in the extremities, and skin discoloration. These symptoms often occur during physical activity and may subside with rest. Q3: What causes PVD? The primary cause of PVD is atherosclerosis, a process where arteries become narrowed and hardened due to the buildup of plaque. Other factors contributing to PVD include smoking, diabetes, high blood pressure, high cholesterol, and aging. Q4: How is PVD diagnosed? PVD can be diagnosed through various methods, including the Ankle-Brachial Index (ABI) test, Doppler ultrasound, and angiography. These tests help assess blood flow and identify blockages in the arteries. Q5: Is PVD a serious condition? Yes, PVD can be a serious condition if left untreated. It can lead to complications such as chronic pain, difficulty walking, non-healing wounds, and in severe cases, tissue loss or gangrene. Q6: Can PVD be prevented? A6: Yes, PVD can often be prevented or its progression slowed. Lifestyle changes such as quitting smoking, adopting a heart-healthy diet, engaging in regular exercise, and managing underlying conditions like diabetes and hypertension can reduce the risk of PVD. Q7: What are the treatment options for PVD? Treatment options for PVD include lifestyle changes, medications (antiplatelet drugs, statins), minimally invasive procedures (angioplasty, stenting), and surgical interventions (bypass surgery). The choice of treatment depends on the severity of the condition and individual factors. Q8: Can PVD be managed without surgery? Yes, PVD can often be managed without surgery. Lifestyle changes and medications are effective in many cases. Surgical interventions are considered when other treatments are ineffective or when there is severe arterial blockage. Q9: Is PVD more common in older adults? Yes, PVD becomes more common with age. However, it can affect people of all age groups, especially those with risk factors such as smoking and diabetes. Q10: Where can I find support and resources for PVD management? Support groups, healthcare providers, and online resources can be valuable for individuals managing PVD. Consult your healthcare professional for guidance and explore reputable sources for information and assistance. Conclusion In conclusion, understanding PVD is the first step towards effective management. By recognizing the symptoms, addressing risk factors, and collaborating with healthcare professionals, individuals can navigate the challenges posed by PVD with confidence. Remember, early intervention and a proactive approach are key to ensuring a healthier, more vibrant life despite PVD.

#Arterial_insufficiency #Arteriosclerosis #Artery_blockages #Atheroembolic_disease #Atherosclerosis #Atherosclerotic_arteries #Blood_circulation_issues #Blood_vessel_narrowing #Claudication #Intermittent_claudication #Leg_pain_due_to_poor_circulation #Limb_blood_flow_problems #Lower_limb_ischemia #PAD_Peripheral_Arterial_Disease #Peripheral_artery_disease #Vascular_disease #Vascular_disorders #Vascular_health_condition #Vascular_occlusive_disease #Vaso_occlusive_disorder #Vasoconstriction

[dduane]

...Going through some old files and coming across this (which I haven’t thought of in a while)...

I told y’all that with a little work, we could make a wizard out of him.  :)

#Doctor Strange #Young Wizards meta #(with a tip of the hat to Chris Claremont) #temporospatial claudication #so what if it got a bit misspelled

[youkah]

for those who don't know I'm disabled and going downhill pretty fast, who wants to place their bets on what I have. It's spine related most likely. I think it's spinal stenosis. Hopefully I find out next week after my MRI that I have to get up at 6 am for -_- My mom is going to see about applying for a handicap sticker for the car so that my brother (who is also disabled) and I don't have to walk far when we go out with her... never thought I'd be this disabled by 21 but oh well lol

#text #disability arc #that's my new tag for talking about this #tldr my back is so bad it hurts to walk or stand or even sit up #I'm in constant pain and pain killers don't work #I can't run anymore #I have neurogenic claudication #I can't walk for more than a couple minutes without being in pain #they're thinking spinal stenosis but my body is insane so who knows what the fuck it'll be

[cryptid-immortality]

its very unpog of cigna to deny my diagnostic spinal mri and require six weeks of treatment before they’ll pay for it. when it’s a diagnostic MRI. they don’t know why im in pain. come on cigna its disability pride month!

#chronic illness #actuallydisabled #ive had claudication for a YEAR now and its not getting better. #my hands go numb when im doing my HOBBIES and its making me SO UPSET #i think its Ankylosing spondylitis #bc the symptoms line up rly well #i have upper back stiffness (around my shoulders and neck) which is apparently more common in dfab ppl #the neuropathy #and my inflammation markers in my blood arent elevated (which happens in 50% of ppl with AS) #so like. im SO HOPEFUL #ive been tested for a ton of things already and i just want answers. ive already come to the conclusion that im physically disabled but i #i want to know whY and if its going to GET WORSE #and also accomodations for uni. stairs my beloathed. on bad days my knees hurt but ONLY ON STAIRS and if I have to go up and down stairs. ow

[samreensway]

HISTORY TAKING STATION OF LOWER LIMB CLAUDICATION 

HISTORY TAKING STATION OF LOWER LIMB CLAUDICATION MRCS B OSCE - MOCK EXAM Bli medlem i kanalen för att få åtkomst till flera förmåner: https://www.youtube.com/channel/UCkkvon_blxinTHc7DGuYkpQ/join

#youtube #history historytaking lowerlimb claudication smoking medicine doctor surgery health medical healthcare mrcs mrcsbosce femalesurgeon youtube

[janitorjuliann]

i think vascular is a genuinely super interesting field of medicine. but unfortunately it doesn't really lend itself to the sort of drama they make movies or tv episodes or indeed fanfic aus about

#in your ship who is the one with PAD and increasing claudication and who is the one telling them every six months to just stop smoking for f

[clonerightsagenda]

Reading Exordia and it just used 'claudication' as in spacetime pocket and 'hesper' as a universal virtue back to back so my young wizards senses are tingling.

#presumably a coincidence. however #also the vibes of these two books are hysterically different

[caffeinatedcamus]

Enneagram Subtype Trait Structures

Enneagram Two

SP 2 - Dependent, timid, victim, idealizer, "it compares", "be necessary", fanciful, condescending, hypersensitive to criticism, envious/ fear of envy, tender, possessive, jealous, arrogant and egocentric, sadistic, paranoid and controlling, castrator and vindictive, self- indulgent, fickle

SO 2 - Omnipotence, cold, egocentric, demanding and hypercritical, contemptuous, rebellious and tyrannical, intolerant of limits, intolerant of criticism, competitive, hunger for success and blindness to failure, envious

SX 2 - Aggressive, hypersensitive, "idolater of desire", impulsive and limitless, dependent , histrionic, rebellious and transgressor, hedonistic, idealized self-image, inconsistent, universal giver, anti-intellectual, competitive, unconventional, erotic movements, seemingly loose hips, affectivity disconnected from sexuality, difficulty in delivery, happy, big spender, fear of failure;

Enneagram Three

SP 3 - Be the best; being useful, self-sufficiency, control, hyperactivity, helping compulsion, being a reference person, confluence, the banishment of error, competitiveness, order, knowing how to sell

SX 3 - Dependent on the gaze of the other, sweet/maternal, complacent, ambiguous in sexuality, devalued, shy and insecure, naïve, chameleonic, frivolous and superficial, controlling, cold/hard/insensitive, perfectionist, critical/demanding, efficient, competitive/envious, repressed aggression and rage, psychosomatic, disconnected, anxious, proud/arrogant; does not show you need & self-sufficiency

SO 3 - Competitive, vindictive, histrionic, chameleonic/simultaneous multifaceted, inverted masculinity and femininity, manipulative when giving and receiving, appropriationist, avoidance of the experience of death/frozen, attached to money, attached to the image of his home, scatologically modest, seductive, studied, cheat/liar, professionally independent, fearful/embarrassing/violent/repressed, lazy, interested friend, envious, jealous, ambitious, cold, impatience

Enneagram Five

SP 5 - Retentive, not giving, detachment, fear of being swallowed, excessively docile, self-sufficient, emotionally numb, knowledge oriented, strangeness, guilt, self-demanding, negative, hypersensitive, fickle & renouncing action

SX 5 - Fragile body in a nonconformist spirit, in need of harmony & flees to nature, arid & at the same time hypersensitive, easily destabilized, nostalgic, helpless, does not affirm its place in the world, worthless, undisciplined, vengeful; not doing what is expected, guilty feeling, selfish, self centered, arrogant, seductive, romantic

SO 5 - Idealization, rationalization, compartmentalization, distancing, lack of action and low energy, atmosphere of concealment, desensitization, resignation and difficulty saying no, arrogance, idealization of poverty, stinginess, autistic traits

Enneagram Six

SP 6 -guilty, pursued, accuser, worried, undecided and hesitant, passive, introvert, suspicious, ambivalent, claudicant, submissive, selfish and greedy, nebulous, inhibited, unsafe, slow, dreamer

SX 6 - hesitant and insecure, reckless, challenging, suspicious, anxious, paranoid, cynical, defensive accuser, aggressive, loyal, critical and authoritative, rebel, observer, inhibited, shy, afraid of tenderness, enduring, braggart, honest, competitive

SO 6 - alienation, anxiety and doubtful rumination, chronophobia, retentivity, metaphysical attitude, taboo of selfishness, norm and mimicry, power games, displacement of authority, uniformity, omnipotence and impotence, omnipresence of guilt, self-accusation, fear of freedom, propensity for psychic ideals and shelters, domestication and obedience

Enneagram Seven

SP 7 - Bon vivant, ironic/cynical/sarcastic, self-indulgent, with acquired rights, envious, excessive, aggressive, utilitarian and strategist, impatient / bored, insubordinate and rebellious, selfish and individualistic, prone to corruption, fraudulent and talkative, schizoid vs. austere seductive extravagance, dry, distrustful and skeptical, tenacious and earthy

SX 7 - Talkative, bombastic / exaggerated, exhibitionist, invasive, impertinent and brazen, "clown" with such a sense of ridiculous, self-referential, magical thinking dreamer, pseudo-empathic, selfish, fraudulent, rabid, anti-hierarchical and escapist, clueless, childish optimism, impatient / impulsive and intolerant of frustration, hypochondriac

SO 7 - Narcissistic, selfish, envious / intolerant of frustration, excessive, good and helpful; holy, guilty, hidden rebel who devalues ​​authority, planner / idealist, skeptical with authority, competitive masked, fearful of conflict, theatrical, hedonistic, seductive, abandoned, charlatan

Enneagram Nine

SP 9 - Renunciatory, distant, emotionally insensitive and distrustful, physically insensitive, reactive and rigid, kind and insecure, resistant to change, voracious in his inertia, imaginative, dependent, avoidant of change, avoidant of choosing, concrete, low self-esteem, rebel, timid, procrastinator, sacrificing, involuntary and attached, autonomous, anticonventional, without limits, simple

SX 9 - Very patient,  without nuance — black or white, tolerant with the other; severe with themselves, chameleonic, above authority, blind faith, mediator and peacemaker, aversion to change, accurate in the development of tasks, love of food as a shared pleasure, dormouse, difficulty with physical contact, ashamed of communicating feelings, incapable of making decisions, bad relationship with the body and sexuality, hyperadaptive, “indispensable” and docile, empathetic, cozy, sense of duty, susceptible to criticism, disorganized or extremely orderly, talkative or mute, inconstant, pedantic, unkempt, autonomous, hyperactive or distracted SO 9 - Social and kind, good host, emotionally intuitive, chatterbox, hyper-available, tendency towards addiction, workaholic, impatient and impulsive, responsible and collaborative leader, against the abuse of power, curious, clueless, idealistic, naïve

Source: https://docs.google.com/document/d/1iFadp6W3OSXl2Ax6rsxD2DXFOjK-na5zYNCVbZE9J4I/edit#heading=h.j2fzqrdskzat

#enneagram #typology #enneagram 2 #enneagram 3 #enneagram 5 #enneagram 6 #enneagram 7 #enneagram 9

[mcatmemoranda]

The pt was already on lisinopril, amlodipine, ASA, atorvastatin, and liraglutide. No need for DAPT in pts with PAD; it just increases bleeding risk.

#cilostazol #PAD #intermittent claudication #claudication

[twsthc]

octavinelle hcs and projections 🦑🦈

⚠️ warnings: self harm, restrictive eating disorders, self destructive behavior below the cut! there are wholesome hcs too i swear

last updated: nov 10, 2023

collective headcanon: jade and azul learned the common language from textbooks (which is why they talk formally), but floyd learned from listening to sailors speak.

╰ underwater merfolk communicate through clicks + other sounds

FLOYD LEECH !! 🦈🫧

🇯🇵🇧🇧🌺 UNLABLED + GENDERFLUID (he/any)

APPEARANCE HCS:

floyd is mixed with black and tan (#D9AD91- Salmon Sand in the winter)

i think he has really large freckles across his body. i hc him to be bajan because this is the species of moray i hc the tweels to be

╰ i also made a deranged twitter thread about this

floyd has a shit ton of scars and even bite marks from old "play fights"

his two rows of moray teeth manifested in his human form as extra overgrown teeth. he doesn't mind because he thinks they look cool

in merform, both he and jade have two sets of teeth and a pharyngeal jaw

RANDOM HCS:

floyd is 1 inch taller than jade and makes sure jade knows it

bites his tongue and the inside of his cheek on purpose and on accident

she has been banned from painting her nails or doing anything messy other than cooking inside of the lounge ever since The Incident.

floyd has ataxia symptoms on land and is a part-time cane user

has severe mamas boy syndrome and will freak out if he cant talk to her at the end of each week about what he accomplished (didnt bite anyone for the WHOLE day)

he thinks its so cool you can put colors in your hair and on your face above water (why i think he'd be into decora and scene)

enjoys okinawan gyaru styles and traditional hawaiian culture/fashion also

it has BPD, GAD, and separation anxiety!!!

triggering content ahead !!

has been a "delinquent" for half his life and has run away a few times

during his depressive episodes he'll forget to eat for days on end

he can also be self destructive during these episodes (self harm)

he can also get really quiet and it scares the shit out of azul (jade is used to it)

gets really (and reasonably) upset when people other than jade or azul mention his mood swings negatively because he's sensitive about it

channels his anger into cooking rather than fighting or cutting

AZUL ASHENGROTTO !! 🐙⛵

🇮🇹🇭🇹🌺 BISEXUAL INTERSEX + TRANSFEM (she/he)

APPEARANCE HCS:

AZUL IS FAT AND HAS BREAST TISSUE (my azul hc art for reference)

in my head she looks like mama morton from the chicago musical

i base azul off of the octopus hawaiiensis, thus the vitiligo

he has longer front teeth and sharper teeth, resembling an octopus beak

rectangular pupils

has splatoon hair 🔥

RANDOM HCS:

i am a drag queen azul believer. one of his dreams is to preform in the lounge

extremely double jointed/a contortionist because. octopus.

doesnt make food in the lounge anymore because its so spicy and ethnic it started scaring the pomefiore customers </3 its not her fault shes haitian...

has severe claudication/phantom limb pains and is a part-time wheelchair user, sometimes she uses a cane. book 6 was really taxing on her legs

GAD, ASPD, and gender dysphoria

triggering content ahead !!

has a restrictive eating disorder

back at his moms restaurant, he would purge after being a taste tester

used to self harm when she was younger but is years clean now!

JADE LEECH !! 🐬🌊

🇯🇵🇧🇧🌺 ASEXUAL AROMANTIC + AGENDER (they/he)

APPEARANCE HCS:

pretty similar if not the same as floyd's

jade is a bit paler than floyd despite going outside more (theyre anemic)

i think his makeup and fashion styles interchange at breakneck speeds

monday evil emo ecopunk , tuesday dainty fairy mushroom enjoyer (still evil)

shaved eyebrows

RANDOM HCS:

similarly to floyd, they use a lot of petnames, but normal ones

╰ instead of "goldfishie," he might call riddle dear/honey

also has extra overgrown teeth in human form but hes self-conscious about it

has milder symptoms of ataxia, also a part-time cane user

really good listener and a really good talker. theyll go on hour long rants about what he found on his daily trek, a new recipe he tried, etc

has a lot of random hobbies! the main ones are swimming, stamp collecting, going on walks, and journaling/scrapbooking

owns those DIY jar terrariums as well as a few mini-aquariums

also owns multiple exotic pets/bugs! i think he owns leeche

GAD and autism. his special interests are botony and wildlife

#twst #twisted wonderland #twst headcanons #octavinelle #floyd leech #azul ashengrotto #jade leech #the tweels #you can tell who my faves are #based on how much i make them suffer #projecting

[dduane]

Sorry if you’ve answered this before, but any tips on improving your technobabble?

I originally came at this problem from two different directions. The first one took considerably more time to enable.

(a) Be familiar (or get familiar) with the languages in which most scientific terms are coined: Latin and Greek.

I took Latin in high school, already knowing that I was a science person and that Latin was considered "the language of science". (And medicine, which also turned out to be handy for me later.) I also started studying Greek in college—and, sigh, I'm still studying it.

Once you're starting to get familiar with the languages, practice coining terms as you need them. While it's considered a failure of style in scientific naming to mix Latin and Greek in the same term, I've found it better to be guided by euphony than a slavish obedience to the rules.

Because sometimes a word or term just sounds right. "Temporospatial claudication", for example, was coined by running a Latin physics term head-on into a medical one. "Claudication" was (and still is in some countries) a term for a constriction in a blood vessel. Its origin in the Latin claudo- and clausum roots is responsible for the Emperor Claudius's name, which would once have implied somebody who limps secondary to such a circulatory problem. I simply bent the term's most basic meaning off into a different direction.

...So you see how that goes. Bang the roots together and see what successfully sticks.

The second approach is a little easier. But only a little.

(b) Base your coined terminology on the conventions and rhythms of real technobabble: by which I mean actual, technical scientific language.

The best way to pick this up in sufficient depth is by reading technical papers in your field of interest—lots of them—so you can see how the pros communicate to/with one another. Every field has its own jargon lying around just begging to be stolen... assuming you observe very carefully how it's correctly used. Otherwise you risk outing yourself as nothing but an interested but insufficiently-committed bystander. You must also be super careful not to screw with the interior grammar of such techspeak... as inevitably it'll have one.

For example: when I was tooling up for writing The Wounded Sky, I spent easily three months reading papers in/on hyperdimensional physics. (Not that I wouldn't have done this anyway. It's a fascinating subject, and before I went into nursing I'd been a physics major, so I had a fair amount of the necessary background to understand what I was reading.) Even in the 80s there were a lot of such papers around, and in those distant pre-Internet days I was helped a whole lot by living just across the road from the impressive science library at Cal State Northridge.

During that period I could be found in the periodicals racks once or twice every week, digging through the monthly journals on the hunt for material that would be germane to the plot I was boiling. I found ten times more goodies than I ever could reasonably have used. The toughest part was winnowing it all down to what I actually needed to scatter here and there for atmosphere's sake, or to plant in specific spots to grease the plot's wheels. (My favorite remains the [legit!] paper with the delightful title, "Taub-NUT Space as a Counterexample to Almost Anything.")

Anyway, I must have got something about that whole business right, since one Princeton physics professor whose work I'd cited at the end of the novel asked me if he could use it in teaching his classes. :)

But there's a third element involved; more an attitude that you apply to what you've produced while employing the first one or two approaches.

You have to treat your coined terms as if they're absolutely real... something that any person educated in the science you're working with would know. The voice and tone in which you write using them has to reflect this absolute confidence and commitment to their reality. Because if you don't—at least while you're writing—absolutely believe in them enough to speak confidently about them, no one else will believe in them either.

But then that's a solid general principle anyway. If you don't do something you've created the courtesy of taking it seriously enough to believe in it (or its reality inside the larger reality you're creating), it won't long survive contact with exterior realities like the inside of your reader's mind.

HTH!

ETA: here's that citation page from the end of Wounded Sky. I believe it remains the only Star Trek novel with a cites list at the end. :)

#technobabble #how to #or a couple of ways to

[siglodeorovibes]

IMPOSTOR SYNDROME

As I spit this words over the paper, I stop and cry again. “What am I even doing?” “What is wrong with me?” “Do I search recognition?” “I just want to be cheered?”

The memories come back, as the voices keep chanting: “Pretentious to write a poem, weak to accept your failure. Give up for your own good, desperation has no cure.”

As they have always done. Always they will say. Seeking mi claudication. Destroying my confidence.

But my pride will stand for me. My desires will shine undoubted. I will keep writing and writing. Even if I am not a poet.

#poetry #poet #poem #poets on tumblr #writers on tumblr #writing #story #words #impostor syndrome #doubt #dark academia

[prismpages]

Stem Cell Therapy for Peripheral Artery Disease in India

Peripheral artery disease, also known as PAD, affects millions of people globally by restricting blood flow to their limbs. Conventionally, treatment options for PAD include medications, lifestyle changes, angioplasty, and bypass surgery.

However, a promising new treatment is emerging - stem cell therapy. In this article, we'll discuss how stem cell therapy works for PAD, research on its effectiveness, and options to access top-quality treatment at r3stemcell India in New Delhi, India.

What is Peripheral Artery Disease?

Peripheral artery disease, or PAD, occurs when fatty deposits called plaque build up in the arteries that supply blood to the head, organs, and limbs. This narrows the arteries and reduces blood flow.

PAD most commonly affects the arteries in the legs. However, it can impact any peripheral arteries outside of the heart. The classic symptom is calf pain or cramping in the legs and hips while walking, known as intermittent claudication. Other signs include sores on the feet/legs that won't heal or color changes in the skin.

PAD is caused by atherosclerosis, a disease where plaque builds up in the arteries. Risk factors for developing atherosclerosis and PAD include:

Smoking High blood pressure High cholesterol Diabetes Obesity Older age

Without treatment, PAD can progress to severe leg pain at rest or non-healing wounds. In rare cases, it may require amputation if blood flow is severely restricted.

How Does Stem Cell Therapy Work for PAD?

Stem cell therapy for PAD aims to regenerate new blood vessels and improve circulation in the affected limbs. It works through the following mechanisms:

Stem cells promote angiogenesis:

Stem cells secrete factors that stimulate the growth of new blood vessels, a process called angiogenesis. They recruit the body's own stem cells to develop new networks that bypass blockages.

Reduced inflammation:

Stem cells have anti-inflammatory properties. They help reduce inflammation in the arteries and vessel walls caused by PAD. This eases blood flow.

Generation of healthy cells:

Some stem cell types can differentiate into endothelial cells, which line the inside of blood vessels. They form new endothelial layers over damaged areas to improve vascular function.

Bypass artery obstructions:

The new blood vessels generated around narrowed or blocked areas provide pathways for blood to flow, bypassing restrictions in the primary arteries. This restores adequate blood flow.

In summary, stem cells repair and regenerate the blood vessel network from within via multiple regenerative mechanisms. When administered via injections, they home in on sites of injury in peripheral arteries and enact healing.

Research on Stem Cell Therapy for PAD

Research into stem cell therapy for PAD is still emerging but shows promise. Here are some key study findings:

A 2021 review found stem cell therapy significantly improved pain-free walking distance in PAD patients compared to conservative treatments alone.

Animal studies show stem cells increase capillary density and blood flow in ischemic limb muscle tissue with minimal side effects.

A 2017 study of 36 patients found adipose-derived stem cell therapy improved ankle-brachial pressure index (a measure of blood flow) and reduced amputation risk.

A Korean trial of 52 participants found bone marrow-derived mononuclear cell therapy increased pain-free walking time by 165% at 6 months follow-up.

No serious adverse events were reported across multiple clinical trials, indicating stem cell therapy for PAD appears safe when administered properly.

While more large-scale human trials are still needed, current research suggests stem cell therapy improves vascular function, reduces symptoms, and helps avoid amputation in PAD patients. Its safety profile also makes it a promising alternative or addition to standard PAD treatments.

Accessing Stem Cell Therapy for PAD in India

For individuals seeking stem cell therapy for peripheral artery disease, r3stemcell India is one of the top centers in the world. Here are some benefits it offers:

Experienced US-board-certified doctors with over 10,000 successful regenerative procedures completed.

State-of-the-art stem cell lab and facilities cleared by DCGI, India's FDA equivalent.

Full evaluation by a medical team prior to developing a customized treatment plan.

Use of autologous (patient's own) stem cells sourced from adipose tissue or bone marrow.

Minimally invasive stem cell injections or intravenous therapies depending on each case.

Affordable all-inclusive packages including accommodation, meals, transportation, and more.

Additional support services like physiotherapy, supplements, and oxygen therapies.

High success rates were reported across multiple conditions treated, including PAD.

For patients who want to access safe and effective stem cell therapy for peripheral artery disease, r3stemcell India is an excellent choice. Consultations can be arranged online or via phone prior to booking treatment.

Conclusion

In summary, peripheral artery disease affects millions worldwide by restricting blood flow to the limbs. While medications, angioplasty, and surgery are standard treatment protocols currently, stem cell therapy shows promise as an innovative option.

Research suggests it improves vascular function, reduces symptoms, increases walking distance and lowers amputation risks for PAD patients. When administered at reputed centers like r3stemcell India, stem cell therapy also appears to be a safe alternative for peripheral artery disease.

With successful clinical studies already conducted and more in progress, stem cell therapy could emerge as an important addition to the PAD treatment paradigm. It offers hope for regenerative healing with minimal long-term reliance on medications. For individuals seeking this promising treatment, r3stemcell India is a suitable choice.

#Peripheral Artery Disease #Stem Cell Therapy #r3stem cell #r3 stem cell therapy #india

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