#glioblastoma

[mindblowingscience]

The striking results offer new hope for patients diagnosed with glioblastoma, one of the deadliest and most common brain tumors in humans.

“Despite recent technological advancements, there is a dire need for new treatment strategies,” says Honggang Cui, a chemical and biomolecular engineer at Johns Hopkins University who led the research. “We think this hydrogel will be the future and will supplement current treatments for brain cancer.”

Cui’s team combined an anticancer drug and an antibody in a solution that self-assembles into a gel to fill the tiny grooves left after a brain tumor is surgically removed.

As reported in the Proceedings of the National Academy of Sciences, the gel can reach areas that surgery might miss and current drugs struggle to reach to kill lingering cancer cells and suppress tumor growth.

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#science #stem #health #medicine #cancer #glioblastoma

[mrsdallohway]

#glioblastoma #Youtube

[sunlitsymposium]

I’ve got a pretty small reach here, but something is better than nothing.

I’ve organized this gofundme for one of my dearest friends, born Roxy, known by close loved ones as Francis.

Francis is losing their battle with brain cancer and we are trying to raise enough money so they can afford the end of life care they need.

If you can share the link, spread this far, it would mean the world. They are one of the most genuine incredible people I know.

Please help, if you can.

#gofundme #glioblastoma #brain cancer #end of life

[spooniestrong]

#car t cell therapy #car t cell #SpoonieStrong #spoonie #glioblastoma #medical breakthroughs #Instagram

[cbirt]

According to a recent study from Karl Landsteiner University of Health Sciences (KL Krems), using radiomics and deep learning algorithms can quickly and accurately distinguish between glioblastoma (primary tumors) and brain metastases. The study, which was published in Metabolites, discovered that magnetic resonance-based radiological data of tumor oxygen metabolism provide a solid foundation for discrimination via neural networks. This combination of oxygen metabolic radiomics and AI analysis was discovered to be vastly superior to human expert evaluations in all critical criteria, even when essential oxygen values did not differ significantly between tumor types. The neural networks’ ability to make clear distinctions based on these values demonstrates the method’s potential.

Glioblastoma (GB) and brain metastasis (BM) are the most commonly occurring types of brain tumors in adults. While they may appear similar on traditional MRI scans, they are treated very differently. Accurately identifying a patient’s tumor type can have a significant impact on their outcome. Using new metabolic neuroimaging techniques in conjunction with artificial intelligence has the potential to improve diagnostic accuracy while also making implementation easier in clinical practice. However, this method produces a large amount of data that is difficult to handle in routine diagnostic evaluations.

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#bioinformatics #deep learning #cancer #glioblastoma #metastases #sciencenews

[bpod-bpod]

Picking the Brain

Various cell types in brain tumour biopsies are marked when applying radioactive antibodies for detection by positron emission tomography. This study of glioblastoma uses cell sorting and 3D histology – technique to highlight the tissue make-up – to distinguish cells of the tumour and its environment towards targeted monitoring of specific cell populations

Read the latest published research paper here

This is International Brain Tumour Awareness Week – 29.10–5.11 2023

Image from work by Laura M. Bartos and colleagues

Department of Nuclear Medicine, University Hospital of Munich, LMU Munich, Munich, Germany

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in Science Advances, October 2023

You can also follow BPoD on Instagram, Twitter and Facebook

#science #biomedicine #neuroscience #neurobiology #biology #glioblastoma #gbm #brain cancer #brain tumour #cancer #oncology #pet scan #histology #antibodies #radiolabelling #radioisotopes #international brain tumour awareness week

[cannabisnewstoday]

#cbd #glioblastoma #cannabis #marijuana #weed #pot #legalization #medical marijuana #mmj #medical cannabis #legalize #nih #national institutes of health

[wardenforaking]

// Hi guys

So.. this wasn’t ever a post I thought I’d ever have to make. But here I am.

Today… I found out that my Father has stage 4 cancer. He has Glioblastoma. An aggressive form of brain cancer. He is to start his first round of radiotherapy within three weeks. He is to go each and every day (excluding weekends) for 6 whole weeks before moving onto chemo (tablet form)

If the treatment shows signs of it working, my Father is looking at a possibly 5 years max. If it doesn’t…. 12-18 months max.

Right now…it’s a lot to process. My head is everywhere. My mental health is severely shot. And on top of all this, I may have to plan two funerals due to my grandmother having end stage Alzheimer’s.

I’m not one to ask given the current state of people not being able to put food on the table for their family or a roof over their heads. But should you be willing, all I ask is for you to consider making a donation to Cancer Research UK. Perhaps we may finally find a cure for cancer together.

#out of kingly duties #cancer #glioblastoma #cancer sucks #cancer research

[worms-unstrung]

may is brain tumor awareness month

the 5 year survival rate for people with malignant brain tumors is only 35.7%. an estimated 1 million americans are living with a brain tumor. nearly 20,000 americans are expected to die from malignant brain tumors this year. for those with a gliomastoma the average life expectancy after diagnosis is only 8 months. although glioblastomas have been known about since the 1920s, there is still no cure. this may, spread awareness and consider donating in the hope of finding a cure.

#brain cancer #in may we wear gray #go gray in may #gray may #glioblastoma

[splitskullfoundry]

Well, my scar looks better and I started Optune therapy at the end of January. I literally only take it off to shave my head and put new arrays on. It'll give me a few extra months, but the clock is ticking. I still have 8 more months of chemotherapy cycles but it's slowed as far as actually doing something. Never take time for granted. I gave up being mad at those who wronged me. And I apologize to anyone who I've done wrong too. I've made my peace.

#glioblastoma #cancer #brain cancer

[intentkitten]

My GF has been trying to raise money for monthly cancer care and outstanding medical bills. Please consider donating 💜 reposting 💜 commenting

#cripple punk #disability #actually disabled #disabled #interracial love #mutual aid #black history #black history month #disabilties #disability awareness #actually autistic #black and disabled #cpunk #cpunk discourse #medical neglect #medical racism #gaypride #queer love #cancer awareness #glioblastoma #lymphoma #cancer sucks #fuck cancer #spread awareness #autizzy

[mrsdallohway]

#glioblastoma

[yvmoveon]

woke up thinking up about some of my glioblastoma patients ive had and if they are still alive. i remember learning about glioblastoma’s prognosis and i had a realization breakdown. i remember this Brazilian woman we literally were laughing all day together. She was super cool. And then i remember this man who was 42 and so sweet and kind. They were all walking and having the time of their lives. 🥲 They were some of the best patients i’ve had. It’s been a year and I just hope they’re all alive and are ok.

also thinking about the pt who started calling me his daughter and gave me his number and had me promise to call him to check up on him occasionally and i accidentally threw his phone number away. i still think about it until today. i hope he doesn’t think i didn’t call cause i didn’t want to. i always think about if he’s ok. :/

Life is so fickle man.

#glioblastoma #p #a #cancer sucks #is it too early for this? yeth #but i can’t help it #i hate my mind #i should have saved it on my phone 🥲

[upsidedownbeatcancer]

28th January 2023 Saturday- my husband complained about his vision problem. He went straight to ophthalmologist and they said nothing is wrong with his eyes and told him to go straight to hospital. He went to hospital. They did his scans. My husband never came home that day. He said they told him to stay for more scans.

Sunday (29th Jan) came and he still didnt come home. He called me that they need to do operation in his head because there is an abscess inside.

8th February 2023 - after the brain operation we got the result of my husband’s biopsy. Unfortunately he has brain cancer called Glioblastoma. This is where the story will begin. I want to take down every journey in this blog like a diary.

This hurts so much because I just gave birth to our son last 5th January which was suppose to be a happy year.

#brain cancer #glioblastoma #cancer #newborn

[cbirt]

Federated Machine Learning Powers the Biggest Brain Tumor Study to Date while Protecting Patient’s Data

Federated machine learning enables the largest brain tumor study ever conducted without sharing patient data by allowing researchers to securely analyze distributed datasets while maintaining data privacy. The breakthrough research from Penn Medicine and Intel Corporation published in Nature Communications has the potential to revolutionize medical research and improve our understanding of brain tumors. It also provides a secure way for organizations to collaborate on large-scale studies while protecting patient data.

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#bioinformatics #glioblastoma #brain tumor #machinelearning #ai #patient data #meded #science news

[bpod-bpod]

Undividing Attention

Since cancers arise when cells divide uncontrollably, you might think the one part of a tumour we don’t need to worry about is a group of cells that aren’t dividing. But recent research has suggested that these ‘senescent’ cells might be important to cancer development and a potential target for treatments. Researchers investigated senescent cells in glioblastomas – deadly brain tumours – in mice and human samples (extracted mouse glioblastoma cells pictured on an artificial matrix for growth and experimentation). Senescent cells make up less than 7% of the tumours, but removal of them resulted in improved survival of mice. With further experiments they identified a key protein, NRF2, coordinating senescence and found similar gene expression in these cells in mouse and human tumours. Cancers with a higher proportion of senescent cells are associated with shorter survival times, and new approaches targeting senescence could supplement existing treatments, improving the prognosis for patients.

March is Brain Tumour Awareness Month

Written by Anthony Lewis

Image from work by Rana Salam and Alexa Saliou, and colleagues Isabelle Le Roux Lab

Paris Brain Institute (ICM), Hôpital Pitié-Salpêtrière, Inserm U 1127, CNRS UMR 7225, Sorbonne Université, Genetics and Development of Brain Tumors Team, Paris, France

Image originally published with a Creative Commons Attribution – NonCommercial – NoDerivs (CC BY-NC-ND 2.0)

Research published in Nature Communications, January 2023

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#science #biomedicine #brain tumours #neuroscience #neurobiology #oncology #cancer #brain cancer #glioblastoma #gbm #our brain bank #immunofluorescence #jackson pollock #sci art #brain tumor awareness month #brain tumour awareness month