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#hypoxia
mindblowingscience · 1 year
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​Videos posted to social media showed boats plowing through a blanket of dead fish smothering the water, with the surface barely visible underneath.
​The New South Wales government said on Friday that "millions" of fish had died in the Darling River near the small town of Menindee, in the third mass kill to hit the area since 2018.
​"It's horrific really, there's dead fish as far as you can see," Menindee local Graeme McCrabb told AFP.
​"It's surreal to comprehend," he said, adding this year's fish kill appeared to be worse than previous ones.
​"The environmental impact is unfathomable."
​Populations of fish such as bony herring and carp had boomed in the river following recent floods, according to the state government, but were now dying off in huge numbers as floodwaters receded.
​"These fish deaths are related to low oxygen levels in the water (hypoxia) as flood waters recede," the government said in a statement.
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auntie-doom · 11 months
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Folks, my POTS is broken.
This is easily one of the most bizarre things in my life with this lemon of a body. I've been experiencing this predictable heart rate jump when I stand up, without fail, for over three decades... until the heart rate increase started failing mid-leap.
I thought I just wasn't recovering from a cold in March, went to the doc in late April; my lungs were clear, no high WBC, wasn't a secondary infection. But the symptoms were apparently consistent with heart or lung damage. Doc sent me to the ER. The ER chest CT was clear, but while I was hooked to the ER machines I noticed my oxygen saturation kept doing this slow dropping down to alarmingly low levels--and I felt fine--then slow climbing back to 99%. A few minutes later I was hit by intense fatigue & pain.
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I checked it on the fingertip pulse/ox after I got home, still happening, but fingertip machine had difficulty with motion and rapidly changing numbers. I got a wearable bluetooth pulse/ox. I'm still seeing the oxygen saturation dips and it's pretty terrifying, yes, WTF is this meat machine doing now? (My doc thinks leakage between oxygenated and deoxygenated blood, which is not reassuring at all. I have a cardiac referral.)
But seeing my POTS get tripped partway through a jump is *freaky*.
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Look at that (about 11am). That's not right. My heart rate started to do the typical POTS jump and crashed to below 50 instead, coinciding with a dramatic O2 drop. What the hell. (full screenshot under readmore)
How long has it been doing this? Is my physical hardware just unable to react to the dysautonomia "speed up" signals? Is this why the fatigue has been increasing way past reasonable?
I had a heart ultrasound and multiple EKGs during the POTS diagnosis, but apparently what I need is a heart ultrasound with "bubble test," which I have never had. I even wore a pulse/ox for a sleep study but this doesn't happen at night! Mostly. It does coincide with activity... frequently... sometimes I am not doing anything... but almost always I am awake.
My POTS is broken and I am so weirded out.
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Whump Prompt #1106
@thebewingedjewelcat asked:  Do you have any being choked prompts?  One of my OCs has a phobia about his neck being touched.
Choking doesn't just have to be hands on the throat. Your whumper could notice how the whumpee actively tries to pull away when their hands get too close to their neck.
“Oh darling, don’t worry, I wont lay a hand on that pretty neck of yours.”
Instead, they use other methods:
Pulling the whumpees shirt around their neck. 
If they’re wearing a tie: it could be tightened to the point of near strangulation.  
Chains/belts/rope could be looped around their neck. Just looped and hanging loose. Just enough to drive your whumpee crazy.
The sudden tightening of the previous items jolting your whumpee awake. 
To keep the whumpee subdued when transporting them, they loop a collar and leash around his neck. They make sure to pull extra tight when your character steps out of line :)
When all the chafing/pulling causes injuries, the whumpee makes sure to keep the bandages nice and tight to cause more pain and suffering. 
After all is said and done, your whumpee panics anytime something nears their neck - even the collar of a t-shirt!
And a little added bonus... what about the potential for hypoxia and brain injury?
After all... the whumper promised they wouldn’t lay a hand on their neck.
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arecaceae175 · 1 year
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if youre still doing them, unconscious for the three sentence fics! (as a continuation to running out of time) ❤️
(Continuation of running out of time)
“Hurry!” Wild yelled, even though it left his gasping for air. He put one hand on his throat and left the other wrapped around Sky’s limp shoulders.
The other heroes were close. Wild could finally hear them. They had to be careful not to collapse the cave further, but Wild’s heart beat faster with every passing second.
“Is Sky with you?” Someone yelled. Wild barely heard it through the rocks. He sucked in as deep a breath as he could, but was overcome by a fit of coughing. Wild was left gasping, black spots dancing in his vision, and he felt himself leaning more heavily against Sky.
Was there a question? Why was he trying to talk?
“Champion!”
The yell pulled Wild out of the haze. He blinked his eyes rapidly and tried to control his breathing.
“Is Sky with you?”
Wild blearily looked at Sky. He was curled up at Wild’s side, and if Wild didn’t look too closely at his blue lips Sky almost looked peacefully asleep.
“Wild, are you there? Is Sky with you?”
The voice sounded stressed. Maybe Wild could help. Wild shook his head to clear his foggy mind and allowed himself three full breaths before he answered. “Unconscious,” he yelled as loud as he could.
There was a response, Wild thought, but he was too tired to make it out. Wild let his eyes slip shut and head rest on Sky’s. The other heroes would be here soon; surely a nap wouldn’t hurt.
(Next part ->)
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wolfeyedwitch · 2 years
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Auction of Evil, Part 2
No. 1 A LITTLE OUT OF THE ORDINARY
Adverse Effects | Unconventional Restraints | "This wasn't supposed to happen"
Have some pining and miscommunication. (Also some medical inaccuracies. I tried, but I am not a doctor.)
CW: dissociation(ish?), Bailey's crappy headspace, offscreen non-con drugging, sedation, asphyxia/hypoxia, adverse drug reactions (more explanation in tags)
Masterlist
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I am ice. I am stone. I feel nothing. 
Bailey repeated the words to themself silently as Slipknot summoned them to the stage, bringing them to heel with a click of their fingers. 
It was Bailey’s mantra now; it had been since… since it happened. By the time of the auction, Bailey was numb to their surroundings. The last thing that they had truly felt was Slipknot’s… displeasure, when they found out that Bailey had been holding back in their fights against Foxfire. 
The punishment had been severe, but Bailey had become used to those by now. It seemed they couldn’t do anything right anymore; punishments were the norm rather than the exception. That hadn’t been the worst part. 
The worst part was the collar. 
It was slim. It sat beneath the neckline of their suit, not even disrupting their silhouette. It was still obtrusive enough for Bailey to feel it every time they swallowed. 
A constant reminder of their new position.
If you’re going to act like a misbehaving dog, little poppet, then I’ll treat you like one. 
Bailey’s hands shook at the remembered pain, the shocks licking up and down their nerves.
No. No, they weren’t going to think of that. They were stone. 
Stone didn’t care that it had disappointed its mentor. Stone didn’t care that its mentor was determined to get “at least some use out of you, after all the work I put in”.
Stone didn’t care who it was sold to.
Nothing would break through Bailey’s self-imposed numbness. They would survive; nothing else mattered. 
That certainty splintered when Viper brought Foxfire down to the stage, carelessly dropping them like so much baggage. 
Bailey’s breath caught at the sight of the hero limp and unmoving. Were they…?
“And as a bonus, I’ll include custody of the hero Foxfire to whoever wins the bid on Poppet,” they heard Slipknot say. 
Their breath came unstuck from their throat at the confirmation. Their The hero was alive. Foxfire was more valuable alive than dead.
For now.
Bailey ignored the sounds of Slipknot playing auctioneer above them. They focused solely on Foxfire. 
The hero looked… well. Not good, because they were far too still and silent to be good. Foxfire’s personality was as bright and vivacious as the blue fire they named themself after, as the trails left by their own teleportation powers. Seeing them so quiet was unnerving, unnatural. But physically, they looked unharmed. 
(Of course they were unharmed. Heroes weren’t like villains; they looked after their own. And anyway, to the heroes, Bailey’s disappearance wouldn’t have been something worthy of punishment anyway. It would have been worthy of praise. Bailey had no reason to be worried about their nemesis, even beyond the fact that they shouldn’t be worrying about their nemesis.)
Foxfire stared sleepily back at Bailey. Their hazel eyes, usually so bright and mischievous behind their dark mask, looked hazy and dull. They blinked once, twice, eyelids moving slower each time.
Then the eyes didn’t reopen. 
Bailey bit back on their cry of alarm. Nothing good would come of the villains knowing they cared about the hero. At best, it would bring mockery. At worst?
At worst, Bailey would be painting a target on Foxfire’s back. The hero was already going to be sold to the same person as them. If their buyer knew about Bailey’s sympathies, they wouldn’t hesitate to use that as another way to force Bailey’s cooperation.
Bailey wouldn't be helping Foxfire that way. They needed to keep calm, and keep silent. 
Foxfire was fine. Foxfire would continue to be fine. They were just unconscious, drugged with whatever concoction Viper had used. 
It got harder and harder to convince themself of that as they watched Foxfire’s breaths become ever shallower. 
When they could no longer see the hero’s chest rise and fall, Bailey couldn’t hold it in any longer. They had to say something.
“Slipknot, they’re not breathing,” Bailey said quietly.
The hand on Bailey’s neck tightened in a silent warning. 
A warning that Bailey ignored. 
“Slipknot, they’re not breathing,” Bailey repeated, louder this time. 
Their collar activated. Every muscle in Bailey’s body went rigid as electricity coursed through them. Even after the collar deactivated, they still twitched and shook with the after-effects.
Slipknot wanted them silent, and was willing to enforce that behavior through whatever means necessary. If Bailey were smart, they’d shut up and do as they were supposed to.
If Bailey were smart, they never would have been in this situation to begin with. 
“They’re not breathing!” Bailey shouted. 
Foxfire’s lips were starting to turn blue as their body starved of oxygen. Whatever Viper had used, the hero was reacting poorly to it.
“You want to sell custody of a hero?” Bailey continued. “That’s gonna be hard to do if the hero is dead!” 
They twisted in their mentor’s grip to look up at them, hoping to appeal to something, anything, that would make Slipknot listen.
A discontented rumble emerged from the gathered crowd. 
Slipknot stared down at Bailey with amused disdain. When they spoke, it wasn’t amplified for the crowd to hear. These words were just for Bailey.
“You care about if they live or die, poppet?” Slipknot scoffed. “I knew you were weak, but this?”
Bailey just stared pleadingly at them, not daring to speak further.
Slipknot smiled at them, expression devoid of kindness. “You think this would make any difference to them? They're still a hero, little poppet. You know what they'd do to you."
Bailey swallowed hard and nodded. They did know. Captured villains didn’t last long in hero custody—only as long as it took for the heroes to get the information and satisfaction they wanted out of them. Bailey had seen the scars their teammates had from close calls and narrow escapes. 
Bailey wouldn’t be thanked for their actions here. If Foxfire lived through this, they wouldn’t hesitate to capture Bailey. They would pay for their actions against the heroes, and the punishment would undoubtedly be worse after this. After they’d shown that they cared, revealed that vulnerability for any villain here to exploit. 
Maybe it was selfish to want to make sure the hero they cared about admired would survive. Wanting to keep their the hero alive even knowing that Foxfire would be hurt. Would be hurt because of them, something they’d been trying so hard to avoid in their fights. 
If that was selfish? Then Bailey was selfish. 
“Please,” they said. 
Slipknot raised an eyebrow, then shook their head. “Don’t say I didn’t warn you.” With that, they shoved Bailey forward.
Bailey collapsed to their hands and knees, but quickly recovered enough to crawl towards the unconscious hero. They stared down at Foxfire’s limp form, unsure of what to do. 
Think, Bailey, think!
Okay. Foxfire wasn’t breathing. They needed oxygen. Bailey had oxygen, and they knew how to give rescue breaths. 
They could do this. They would save Foxfire, no matter what repercussions it brought. 
Bailey tilted the hero’s head back and pressed their mouth against Foxfire’s. Their cheeks heated as they remembered a scene they had imagined, where this same motion had happened for very different reasons. They ignored their embarrassment; they could blush about this later.
For now? Bailey kept going. They ignored how Slipknot resumed the auction; they tuned out the sound of villains bidding on them. All that mattered was Foxfire, and the terrible intimacy of breathing for another person.
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Taglist:
@heathenville @nonbinary-disaster @kim-poce @whump-world @dolls-circus @pickleking8 @ghostfacepepper @cupcakes-and-pain @badluck990 @mylifeisonthebookshelf @pumpkin-spice-whump @deluxewhump @extemporary-whump @whumpwillow @multiple-characters1-acct @sunflower1000 @fleur-alise @equestrianwritingsstuff, @scp-1296 @livingforthewhump @thingsthatgo-whump-inthenight @suspicious-whumping-egg @kaiwewi @lelly-belly @neuro-whump @newbornwhumperfly @whumpthisway @whumpcreations @wicked-whump @heart4brains @myhusbandsasemni @how-to-be-a-hero @kixngiggles @kurochan @whumpsday @extrabitterbrain @pattonvirglsanders @neverthelass @we-write-as-one @elrysdoesstuff @whumperflies-and-roses @ha-ha-one @whatwhumpcomments @ramadiiiisme @towerlesskey @emmanemanemm @pigeonwhumps
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tanushakyrano · 1 year
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febuwhump day 16: semi-conscious
YES ITS NOT THE 16TH IM SO AWARE OF THIS..... writing the second half of this really sucked for some reason. words were not computing. but i got it done!
characters: Kayo, Alan
additional warnings: hypoxia (low oxygen)
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Alan was getting worried. 
It had been at least five minutes since he’d heard anything from Kayo. It wasn’t exactly unusual; the amount of times that she’d experienced ‘technical difficulties’ and gone dark on rescues was frankly ridiculous. Nine times out of ten, she was completely fine. 
It was the tenth time that worried him.
They’d split up to search for survivors. The space station they were on was large and sprawling, and the internal communication system was down which meant that figuring out where everyone was was just that much more difficult. Most of the crew had already been located, but there were a few names unaccounted for on the crew manifest. They’d agreed to split up to cover more ground quicker. Alan was beginning to think that that had been a mistake.
He turned a corner and suddenly his feet weren’t on the ground any more. It took him a minute to realise what the hell was going on. The station had been experiencing system-wide failures for a while now; lights were only on in about half of the areas he'd explored, and life support systems had given up the ghost a long time ago. Clearly the artificial gravity in some areas was failing entirely. He reached out for the wall, using the handrails to give him momentum as he pushed onwards.
A light flashed red over one of the doors as he passed. Alan glanced into the room that lay beyond, shrouded in darkness, then caught sight of the flashing message just above the locking mechanism: WARNING - HULL BREACH. Sure enough, he could just about make out the gash in the floor, the metal plating warped and jagged. He pushed himself onwards. The ball of anxiety that was pretty much a permanent resident in his chest tightened.
Every room Alan glanced into was completely empty even of other missing members of the crew. The silence - other than the occasional crackle of burnt-out circuits - was starting to unsettle him. He was intensely aware of the fact that the station was slowly tearing itself apart around him. They were on borrowed time.
A flash of teal behind one of the doors caught his eye. Alan made a beeline for it, slamming his hand into the locking mechanism until with a groan, the door slid partway open. It was difficult to get purchase in zero-gee, but he managed it, shouldering it open until the gap was large enough for him to squeeze through.
Oh. The gravity was back.
Alan was a little embarrassed to admit that it took him by surprise. As soon as enough of him was through the door, gravity tugged him determinedly downwards, and he fell unceremoniously to the ground. He banged his shin on the way down and cursed.
He quickly scrambled up, assessing the situation. Kayo was slumped in one corner, head resting against the wall, knees pulled halfway to her chest. She barely stirred at his entrance.
"Kayo? You okay?" He was at her side in an instant, noting her blue-tinged lips with alarm.
Slowly, her eyes opened.
"Alan…?"
"Hey. Hi." Alan tried to smile reassuringly. "Kayo, do you know what happened to you?"
"Circuit…blew." Her brow furrowed with concentration as she attempted to from a sentence. "Oxygen tank. Damaged."
A quick scan of her suit's system confirmed it. Oxygen levels were low and getting lower, thanks to microfractures along one side of her helmet. Alan took a deep breath and tried very hard not to freak out. His hand found hers and held it tightly. Whether it was to reassure Kayo or himself, he didn't know.
"Look, this station could blow any minute," he said, keeping the wobble out of his voice. "We gotta go. You're gonna have to help me out here, I can't carry you all the way. My noodle arms aren't built for this."
It was barely a joke, but Kayo still smiled weakly at it, struggling to push herself upright as Alan slung her arm over his neck and helped her to stand up. He was suddenly very grateful that the gravity had malfunctioned in the corridors outside; even though Kayo was trying her best to help, Alan was single-handedly supporting most of her body weight, and he wasn't sure he could make it back in time if he had to carry her the entire way back.
"M'sorry," Kayo murmured, head dropping against his shoulder. Her voice was so quiet, so…small, that Alan's throat constricted. It was so unlike her that it scared him.
"Hey, no, don't apologise. We're gonna be okay."
She didn't reply.
They headed towards the half-open door, one shuffling step at a time. Kayo could barely keep her eyes open. Alan made a mental note listen to Virgil next time when he stressed the importance of weightlifting in training. Already his shoulders were aching viciously.
The gap was too small to fit through. Alan glared at it as if it had caused him personal offence, slamming his fist into the button several times - as if that would somehow magically open all the way.
Surprisingly, it did.
Alan blinked. Maybe the infamous Tracy luck had decided to go on vacation for the day.
The switch from gravity to lack thereof was much less jarring when he was prepared for it. It also meant that they moved much more quickly, no longer weighed down by artificial forces. Before long, they were nearly back at Thunderbird Three, thudding to the ground again, Alan barely keeping his balance under the renewed burden of Kayo's weight.
"Can I get some help here?" he yelled out, hoping that one of the crew was in earshot. Sure enough, Clove - the one who'd helped them upon their arrival - came hurrying out, ducking under Kayo's other arm and lifting some of the weight off Alan's shoulders - literally.
"The last of the crew made it back while you were away," she informed him. That was good. It meant he could close the airlock for good once they were safely back in Three, make a breathable atmosphere for Kayo.
Three was in arm's reach now.
As soon as their feet crossed the threshold, he slammed the airlock shut, listening intently for the hiss of air that confirmed the establishment of the breathable atmosphere. Carefully, he reached for the clasps on either side of Kayo's helmet, easing it off her head. Clove hovered worriedly next to him.
It was a sign that he was stressed as hell when the sound of Kayo's shuddering inhale was enough to make him flinch violently. Her hand grasped his arm instinctively as her body tried to get much-needed oxygen back into her system.
"You're okay," he breathed, grasping her forearm back. "Thank fuck, you're okay."
"Yeah." Kayo tipped her head back, chest rising and falling steadily. She gave him a weak thumbs up. "Good…job, kid."
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bpod-bpod · 9 months
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Seeing Low Oxygen
Visualising tumour cell oxygen deprivation (hypoxia) in a living mouse model with pancreatic cancer using a new fluorescence microscopy approach
Read the published research paper here
Image from work by Timothy Samuel and colleagues
Princess Margaret Cancer Centre, University Health Network, Toronto, Canada
Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
Published in Science Advances, June 2023
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leyzy · 2 years
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https://jdfor2020.com/2020/11/german-neurologist-warns-against-wearing-facemasks-oxygen-deprivation-causes-permanent-neurological-damage/
Masked people cannot think.
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ghostofmrsaturn · 5 days
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I refrain from even thinking of the idea of em excuse. I know them all. I know. That is a problem. Ignorance is more than bliss. Whatever that word is. Uber-bliss . I live a constant reminder of my own filth. Dirty laundry I can't keep clean?
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drforambhuta · 14 days
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I. Polycythemia Diagnosis:
A. Clinical Assessment:
• The diagnostic process for polycythemia commences with a thorough examination of medical history and physical condition to detect signs indicative of erythrocytosis, assess potential risk factors (e.g., smoking habits, family history of thrombosis), and uncover underlying causes.
• Special attention should be given to symptoms of hyperviscosity syndrome (e.g., headaches, dizziness), skin manifestations (e.g., erythromelalgia), and signs of organ enlargement (e.g., splenomegaly, hepatomegaly).
B. Laboratory Tests:
• Laboratory investigations are crucial for diagnosing polycythemia and understanding its underlying mechanisms. Essential tests include a complete blood count (CBC) with differential, examination of peripheral blood smear, and measurement of serum erythropoietin levels.
• Additional tests, such as JAK2 mutation analysis, bone marrow biopsy, and molecular testing for other mutations associated with myeloproliferative neoplasms (e.g., CALR, MPL), may be necessary to confirm the diagnosis of PV and rule out alternative causes.
C. Imaging Techniques:
• Imaging methods like ultrasound, computed tomography (CT), or magnetic resonance imaging (MRI) may be used to evaluate organ enlargement (e.g., splenomegaly, hepatomegaly) and identify potential underlying factors for secondary polycythemia (e.g., renal tumors).
II. Polycythemia Treatment:
Management of polycythemia aims to alleviate symptoms, lower the risk of thrombotic complications, and prevent disease progression. Treatment approaches may vary depending on the underlying cause and severity, often involving a combination of strategies:
A. Phlebotomy (Venesection):
• Phlebotomy is the primary treatment for PV, involving the removal of excess blood to achieve target hematocrit levels (<45% in men, <42% in women).
• Regular phlebotomy sessions usually start at diagnosis and are adjusted based on individual response and disease activity.
B. Cytoreductive Therapy:
• Drugs like hydroxyurea, interferon-alpha, and ruxolitinib may be used in PV patients who do not respond to or cannot tolerate phlebotomy.
• These drugs work by suppressing abnormal hematopoietic proliferation and reducing the risk of blood clotting, with hydroxyurea being the most commonly used and studied cytoreductive drug in PV.
C. Antiplatelet Therapy:
• Aspirin and other antiplatelet drugs are often prescribed to PV patients with a history of blood clots or other high-risk factors to lower the risk of arterial thrombosis.
• Aspirin is usually started at low doses (e.g., 81 mg daily) and may be combined with cytoreductive therapy for better thromboprophylaxis.
D. Treating Underlying Conditions:
• Management of secondary polycythemia focuses on addressing the root cause to relieve hypoxia-induced erythropoiesis and prevent disease progression.
• Interventions may include oxygen therapy for patients with chronic respiratory problems, correction of hemoglobin disorders or other genetic issues, and surgical removal of erythropoietin-secreting tumors.
E. Lifestyle Changes:
• Lifestyle adjustments such as quitting smoking, maintaining a healthy weight, regular physical activity, and proper hydration are vital for improving clinical outcomes and reducing cardiovascular risks in polycythemia patients.
Doctors suggest undergoing regular health checkups for the early diagnosis and treatment of polycythemia. You can choose to undergo a regular full body health checkup at Jaslok Hospital Mumbai, which is one of India's best hospitals for the early detection and management of blood disorders.
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Whump Prompt #986
Your whumpee is kidnapped but is forced to wear a full-face oxygen mask (think: Avatar) that supplies them with surprise sedatives/actual oxygen. The air quality in the room is so low that If they take it off, they can hardly breathe. The torturer also delights in restricting oxygen flow to the mask whenever they feel like it. This could lead to brain damage/cerebral hypoxia/confusion etc)
(Maybe the pipe supplying oxygen is very short from where it leads through a grate in the wall, so the whumpee had limited movement to get comfortable)
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cebozcom · 1 month
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Climate Change Impact: Oxygen Depletion Threatens Marine Life | CeBoz.com
Rising temperatures from climate change depleting oxygen in coastal waters, threatening marine life
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randomwikiarticles · 3 months
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Helios Airways Flight 522 was a scheduled passenger flight from Larnaca, Cyprus, to Prague, Czech Republic, with a stopover in Athens, Greece. Shortly after take-off on 14 August 2005, air traffic control (ATC) lost contact with the aircraft operating the flight, named Olympia; it eventually crashed near Grammatiko, Greece, killing all 121 passengers and crew on board. It is the deadliest aviation accident in Greek history.[1][2]
An investigation into the crash by the Air Accident Investigation and Aviation Safety Board (AAIASB) concluded that the crew had neglected to set the pressurization system to automatic during the take-off checks. This caused the plane not to be pressurized during the flight and resulted in nearly everyone on board suffering from generalized hypoxia, thus resulting in a ghost flight.
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gavischneider · 3 months
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onlyhurtforaminute · 3 months
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HYPOXIA-BLEED FOR BLASPHEMY
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bpod-bpod · 1 year
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Natural Healing
Many of our best medical treatments are based on boosting the body’s natural capacity for recovery. So understanding the in-built responses activated during hard-to-treat conditions might point towards new approaches. Hypoxic-ischaemic brain injury is a common cause of disability in newborns that comes from a temporary block of the blood supply to the brain, and current treatments are limited to cooling babies down. Now researchers have investigated the role of lactate – produced by muscles during hard exercise when oxygen levels are low. They found that mice lacking a receptor that lactate binds to barely recovered any brain tissue following the injury, but those with the receptor enlisted the restorative action of immune cells (green in the recovering section pictured) and cell cycle to spark new brain cell growth (pink) and partly repopulate the damaged areas. Harnessing this mechanism could provide a route to improving prospects for babies with hypoxic-ischaemic brain injury.
Written by Anthony Lewis
Image from work by Lauritz Kennedy and Emilie R Glesaaen, and colleagues
Department of Microbiology, Oslo University Hospital and University of Oslo, Oslo, Norway
Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
Published in eLife, August 2022
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