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#microfluidics
fuckyeahfluiddynamics · 6 months
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Blood Flow in a Fin
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This award-winning video shows blood flowing through the tail fin of a small fish. Cells flow outward in a central vessel, then split to either side for the return journey. (Video and image credit: F. Weston for the 2023 Nikon Small World in Motion Competition; via Colossal) Read the full article
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mattgrayyes · 1 month
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I can't remember when I last spend a whole day going wow like this, the research has got so much further than I'd have expected!
Matt Gray is Trying: Biomedical Research
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New technique in tiny tool tuning: Making microscopic measurements more accurate
Fluidic force microscopy (FluidFM) combines the sensitivity of atomic force microscopy with microfluidics' capabilities, necessitating precise calibration of its cantilevers for reliable data. Traditional methods, however, struggle with the unique internal structure of FluidFM cantilevers, leading to inaccuracies. A recent study published on February 18, 2024, in the journal Microsystems & Nanoengineering reports an innovative calibration technique for FluidFM micropipette cantilevers, pivotal for exact force measurements in microfluidic environments. The FluidFM is a tiny tool used in microscopic environments to measure forces with high precision. Unlike traditional methods that often fall short due to the complex inner structure of FluidFM cantilevers, this new approach leverages the cantilever's resonance frequencies in both air and liquid environments.
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bpod-bpod · 2 months
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Driving the Tube
Applying advanced microfluidics technology, reveals the role of cells' 'handedness' – a bias for direction of growth – in vessel development
Read the published research article here
Image from work by Haokang Zhang and colleagues
Department of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA
Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
Published in Science Advances, February 2024
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microscope-world · 6 months
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Microfluidics under the ZEISS Stemi 508 microscope.
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techninja · 17 days
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Miniaturizing Innovation: Exploring the Microfluidics Market
In the realm of life sciences and healthcare, the Microfluidics market is emerging as a transformative force, enabling researchers and clinicians to miniaturize laboratory processes and revolutionize diagnostics and therapeutics. This article delves into the burgeoning field of microfluidics, its applications in biomedical research and diagnostics, and its potential to reshape the healthcare landscape.
Microfluidics, the science of manipulating fluids at the microscale, offers a versatile platform for a wide range of applications, from drug discovery and genomics to point-of-care diagnostics and personalized medicine. By leveraging the unique physics and mechanics of fluid flow at small scales, microfluidic devices enable precise control over sample volumes, reaction kinetics, and experimental workflows.
The Microfluidics market encompasses an extensive array of technologies, including lab-on-a-chip devices, microfluidic pumps, valves, and sensors, as well as integrated systems for automated sample preparation and analysis. These miniaturized platforms offer numerous advantages over traditional laboratory techniques, including reduced sample and reagent consumption, faster analysis times, and increased sensitivity and throughput.
One of the key drivers propelling the growth of the Microfluidics market is the increasing demand for point-of-care diagnostics and personalized medicine. Microfluidic devices enable rapid and cost-effective analysis of biological samples, allowing for early detection of diseases, monitoring of treatment efficacy, and tailoring of therapies to individual patient needs.
In addition to healthcare applications, microfluidic technologies are transforming the landscape of biomedical research, enabling researchers to conduct experiments with unprecedented precision and scalability. From studying cellular dynamics and microorganisms to exploring complex biological phenomena, microfluidic platforms offer insights that were previously inaccessible using conventional laboratory techniques.
Moreover, the integration of microfluidics with other emerging technologies, such as artificial intelligence (AI) and advanced imaging techniques, is expanding the horizons of biomedical research and diagnostics. By combining microfluidic devices with AI-powered analytics and high-resolution imaging systems, researchers can extract valuable insights from complex biological data with unprecedented speed and accuracy.
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As the Microfluidics market continues to evolve, collaboration between academia, industry, and healthcare providers will be essential to realize its full potential. Addressing challenges such as standardization, scalability, and regulatory compliance will be crucial to accelerating the adoption of microfluidic technologies across diverse applications and settings.
In conclusion, the Microfluidics market represents a paradigm shift in biomedical research and diagnostics, offering a powerful platform for innovation and discovery. With its ability to miniaturize laboratory processes, enhance analytical capabilities, and enable personalized healthcare solutions, microfluidic technology is poised to shape the future of medicine and healthcare delivery, driving advances that benefit patients, researchers, and clinicians alike.
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yashmedica · 18 days
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From Bench to Breakthrough: How Next-Gen Technologies are Transforming Labs
The laboratory equipment market is thriving, driven by advancements in next-generation sequencing, microfluidics, and automation
The Powerhouse of Discovery: A Look at the Laboratory Equipment Market From groundbreaking research to routine medical diagnostics, laboratory equipment plays a vital role in healthcare. The global laboratory equipment market is anticipated to reach a staggering USD 84.79 billion by 2030, driven by rising demand for advanced technologies and increasing investments in life sciences research. This…
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jcmarchi · 19 days
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Exploring the dynamic world of laser welding - Technology Org
New Post has been published on https://thedigitalinsider.com/exploring-the-dynamic-world-of-laser-welding-technology-org/
Exploring the dynamic world of laser welding - Technology Org
In the realm of manufacturing and engineering, advancements in technology continually redefine the boundaries of what is possible. Among these innovations, laser micro welding stands out as a remarkable technique that has revolutionized the way delicate components are joined together. 
Laser welding. Illustrative photo. Image credit: Chokniti Khongchum via pexels.com, free license
How laser micro welding works
At its core, laser micro welding is a welding possess that utilizes a focused laser beam to join small components with extreme accuracy. Unlike traditional welding methods that often involve heat-intensive processes, such as arc welding or gas welding, laser micro welding operates on a different principle, harnessing the power of coherent light to melt and fuse materials together. 
The different possible applications
One of the key advantages of laser micro welding is its ability to achieve high-quality welds in materials with varying compositions and thicknesses. Whether it’s dissimilar metals, thermoplastics, or even fragile materials like glass or ceramics, laser micro melding offers a level of precision that is unmatched by other, conventional, welding techniques. 
The benefits of laser micro welding
One of the most important features of laser micro welding is its minimal heat-affected zone (HAZ). Unlike other welding methods that can cause deformation, warping, or material damage due to excessive heat, laser micro welding minimizes thermal impact on the surrounding area. 
Efficiency and cost-effectiveness
Laser micro welding also offers practical benefits. It offers unmatched repeatability and consistency, ensuring that each weld meets the highest standard or quality and reliability. This is critical in industries where precision is non-negotiable, such as medical device manufacturing or aerospace engineering, where the smallest defect could have significant consequences. 
The future of laser micro welding
Technology is constantly developing, and so do the potential applications of laser micro welding. From microelectronics and microfluidics to jewelry and dental prosthetics, this technique knows no boundaries. Laser micro welding is on its way to becoming the forefront of innovation.
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nmsc-market-pulse · 1 month
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Innovative Solutions: Microfluidics Market Breakthroughs
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In the ever-evolving landscape of modern science and technology, the Microfluidics Market stands out as a beacon of innovation and progress. With its ability to manipulate fluids at the microscale, microfluidics has revolutionized industries ranging from healthcare and pharmaceuticals to biotechnology and diagnostics.
According to a study conducted by Next Move Strategy Consulting, the global Microfluidics Market size is predicted to soar to USD 24.13 billion by 2030, boasting a remarkable compound annual growth rate (CAGR) of 17.1%. This forecast underscores the industry's significant impact and its potential to reshape the future of numerous sectors.
Revolutionizing Industries:
Microfluidics represents a paradigm shift in how we approach fluid handling and analysis. At its core, microfluidic technology enables precise control over small volumes of fluids, typically in the microliter to nanoliter range. This capability has transformative implications across various industries, particularly in healthcare.
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In the realm of healthcare, microfluidic devices have emerged as powerful tools for diagnostic testing, disease monitoring, and personalized medicine. These miniature systems facilitate rapid and accurate analysis of biological samples, offering insights into patient health with unprecedented speed and efficiency. From point-of-care diagnostic devices to lab-on-a-chip platforms, microfluidics is driving advancements that empower healthcare professionals and improve patient outcomes.
Moreover, the pharmaceutical industry is experiencing a renaissance fueled by microfluidic technologies. Traditional drug discovery and development processes are often time-consuming, resource-intensive, and prone to inefficiencies. Microfluidics offers a solution to these challenges by enabling high-throughput screening, precise dosage control, and miniaturized drug delivery systems. By streamlining workflows and reducing costs, microfluidic platforms are accelerating the pace of drug development and bringing life-saving treatments to market faster than ever before.
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Key Breakthroughs:
Several groundbreaking advancements have propelled the Microfluidics Market forward, unlocking new possibilities and pushing the boundaries of what's achievable. One of the most notable breakthroughs is the development of organ-on-a-chip platforms. These innovative devices recreate the structure and function of human organs on a miniature scale, providing researchers with unprecedented insights into physiological processes and disease mechanisms. Organ-on-a-chip technology has the potential to revolutionize drug testing, disease modeling, and personalized medicine by offering more accurate and predictive preclinical models.
Furthermore, advancements in microfluidic manufacturing techniques have paved the way for the commercialization of portable and affordable diagnostic devices. These handheld systems enable rapid testing for a wide range of applications, including infectious diseases, chronic conditions, and biomarker detection. By bringing diagnostic testing closer to the point of care, microfluidic devices improve access to healthcare, particularly in resource-limited settings where traditional laboratory infrastructure may be lacking.
Additionally, the integration of microfluidics with other emerging technologies such as artificial intelligence (AI) and machine learning (ML) holds tremendous promise for the future. By leveraging data analytics and automation, microfluidic systems can optimize experimental workflows, analyze complex biological samples, and accelerate scientific discovery. AI-powered microfluidics has the potential to revolutionize drug discovery, biomarker identification, and precision medicine by uncovering hidden patterns and insights in vast datasets.
Future Outlook:
As we look to the future, the Microfluidics Market is poised for continued growth and innovation. Advances in materials science, microfabrication techniques, and digital technologies will further enhance the performance and versatility of microfluidic devices. Graphene, for example, has emerged as a promising material for microfluidic applications due to its exceptional electrical, mechanical, and thermal properties. By incorporating graphene into microfluidic devices, researchers can achieve unprecedented levels of sensitivity, throughput, and reliability.
Moreover, increased collaboration between academia, industry, and government agencies will drive cross-disciplinary research and foster the development of novel applications. The convergence of disciplines such as biology, chemistry, physics, and engineering is fueling innovation in microfluidics, leading to breakthroughs that address some of the most pressing challenges facing society. From advancing our understanding of fundamental biological processes to revolutionizing medical diagnostics and drug development, microfluidics has the potential to shape the future of healthcare and biotechnology.
Expanding Applications: As microfluidics technology continues to mature, its applications are diversifying across a wide range of fields. Beyond healthcare and pharmaceuticals, microfluidic devices are finding applications in environmental monitoring, food safety testing, agriculture, and even aerospace. These expanding applications highlight the versatility and adaptability of microfluidics technology, making it a valuable tool in addressing multifaceted challenges.
Global Accessibility: One of the key advantages of microfluidics is its potential to democratize access to advanced scientific tools and technologies. Miniaturized and portable microfluidic devices can be deployed in remote or resource-limited settings, bringing diagnostic capabilities to underserved communities around the world. This global accessibility has the potential to transform public health initiatives, disease surveillance efforts, and disaster response strategies.
Sustainability: Microfluidics offers inherent advantages in terms of sustainability and resource efficiency. By minimizing sample volumes and reagent consumption, microfluidic systems reduce waste generation and environmental impact compared to traditional laboratory techniques. Additionally, the scalability of microfluidic manufacturing processes enables mass production of devices with minimal material usage, further contributing to sustainability efforts.
Personalized Healthcare: The advent of microfluidic-based personalized medicine promises to revolutionize healthcare by tailoring treatments to individual patients' genetic makeup, physiology, and lifestyle factors. Microfluidic devices enable precise analysis of biomarkers, genetic variants, and drug responses, allowing clinicians to prescribe targeted therapies with optimal efficacy and minimal side effects. This shift towards personalized healthcare has the potential to improve patient outcomes, reduce healthcare costs, and enhance overall quality of life.
Education and Training: Microfluidics is increasingly being integrated into educational curricula at various levels, from undergraduate laboratories to specialized graduate programs. Hands-on experience with microfluidic devices provides students with practical skills in experimental design, data analysis, and interdisciplinary collaboration. Furthermore, microfluidics serves as a platform for teaching concepts in fluid dynamics, biochemistry, and biophysics, fostering a deeper understanding of complex biological systems and technological innovation.
Regulatory Considerations: As microfluidic devices become more prevalent in clinical settings, regulatory agencies are faced with the challenge of establishing guidelines and standards for their safe and effective use. Ensuring the quality, reliability, and performance of microfluidic devices requires collaboration between industry stakeholders, regulatory bodies, and healthcare professionals. Regulatory considerations such as device validation, quality control, and data integrity will play a crucial role in shaping the future of the microfluidics industry and its impact on healthcare delivery.
In conclusion, the microfluidics market is a hotbed of innovation, offering transformative solutions that have the power to change the world. By leveraging breakthrough technologies and embracing interdisciplinary collaboration, the microfluidics industry is paving the way for a future where healthcare is personalized, medicines are tailored to individual needs, and scientific discovery knows no bounds. As we embark on this journey of exploration and discovery, the possibilities are endless, and the potential for impact is profound.
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poonamcmi · 9 months
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Global Microfluidics Market Is Estimated To Witness High Growth Owing to Increasing Adoption of Microfluidic Technology
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The global microfluidics market is estimated to be valued at USD 20.7 billion in 2021 and is expected to exhibit a CAGR of 23.2% over the forecast period of 2021-2026, as highlighted in a new report published by Coherent Market Insights.
A) Market Overview:
The microfluidics market encompasses the design, fabrication, and manipulation of fluids through microchannels, where the dimensions range from micrometers to millimeters. This technology has gained significant attention due to its various applications in healthcare, pharmaceuticals, biotechnology, and other industries. Microfluidic devices offer advantages such as precise control over fluid flow, low sample volumes, high throughput screening, and integration of multiple functions into a single device.
B) Market Dynamics:
The driving factors for the growth of the Microfluidics Market include increasing adoption of microfluidic technology in the healthcare and pharmaceutical industries. Microfluidic devices are extensively used in applications such as point-of-care diagnostics, drug discovery, genomics, proteomics, and cell-based assays. These devices enable rapid and accurate analysis of biological samples, leading to better disease diagnosis, personalized medicine, and drug development. Additionally, the miniaturization of laboratory processes saves time, reduces costs, and requires lesser reagents.
Another driver for market growth is the demand for microfluidics in research and development activities. The increasing need for high-throughput screening and miniaturization of experiments has led to the adoption of microfluidic devices in academic and industrial research institutions. These devices enable automation and integration of multiple processes, thereby enhancing productivity and efficiency.
C) Market Key Trends:
A key trend in the microfluidics market is the integration of microfluidic technology with other emerging technologies such as nanotechnology, 3D printing, and artificial intelligence. This integration enables the development of advanced microfluidic systems with improved functionalities and capabilities. For example, the combination of microfluidics with nanotechnology allows the fabrication of nanostructured surfaces for enhanced fluid manipulation and sensing.
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UltraGenizer High Shear Homogenizer:UltraGenizer is a laboratory ultra high pressure processing device. It is an electrically-driven and bench-top high shear homogenizer, which requires no compressed air or hydraulic oil to achieve maximum 4,200 bar (60,000 psi) operating pressure.
Application of UltraGenizer High Shear Homogenizer:Nano emulsions  Nano dispersions Liposomes Nanoparticles Graphene Deagglomeration 
Performance of UltraGenizer High Shear Homogenizer:Energy efficient, 1/2 energy loss of the most homogenizers Small (integrated design delivers the light weight and small dimensions) Smart (programming control systems confer diligent functions: controlled inlet volume ± 0.1mL; auto stop with time/volume) Silent (noiseless performance) Strong (more than 150 mL/min at 60,000 psi) CE compliant and RoHs compliant
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genizer-homogenizer · 11 months
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Aerosol jet printing could revolutionize microfluidic device fabrication
Surface acoustic wave (SAW) technologies, known for their high precision and rapid actuation, are essential to microfluidics and affect a broad spectrum of research areas. However, traditional fabrication methods are time-consuming, intricate, and necessitate costly cleanroom facilities. One novel method overcomes these constraints by utilizing aerosol jet printing to create customized devices with various materials, such as silver nanowires and graphene, significantly reducing development time. In a study published in Microsystems & Nanoengineering, researchers from Duke University and Virginia Tech have pioneered the integration of aerosol jet printing technology into the fabrication of SAW microfluidic devices. This advancement offers a faster, more versatile, and cleanroom-free approach to developing lab-on-a-chip applications, revolutionizing fields from biology to medicine.
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bpod-bpod · 6 months
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Nerve Culture
Results of the Nikon Small World Competition are out! BPoD is delighted to feature a selection of those images coming from the world of biomedicine
In 10th place Melinda Beccari & Dr. Don W. Cleveland of UC San Diego Department of Cellular and Molecular Medicine La Jolla, California, USA with their image of motor neurons grown in a microfluidic device for separation of cell bodies (top) and axons (bottom) showing microtubules in green and actin of growth cones in red. The image was made using confocal fluorescence microscopy at 20X objective lens magnification
Image by Melinda Beccari & Dr. Don W. Cleveland
UC San Diego Department of Cellular and Molecular Medicine La Jolla, California, USA
Image copyright held by Melinda Beccari & Dr. Don W. Cleveland; Image received courtesy of Nikon Small World
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wissenresearchllc · 1 year
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Advanced Microfluidics and Organ-On-Chip Technology
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innonurse · 1 year
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A novel microfluidic cancer detection and treatment technology
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- By InnoNurse Staff -
The Static Droplet Microfluidic device can detect circulating tumor cells that have broken free from a primary tumor and entered the bloodstream.
Read more at University of Technology Sydney
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