By taking biopsies from long COVID patients before and after exercising, scientists in the Netherlands constructed a startling picture of widespread abnormalities in muscle tissue that may explain this severe reaction to physical activity.
Among the most striking findings were clear signs that the cellular power plants, the mitochondria, are compromised and the tissue starved for energy.
"We saw this immediately and it's very profound," says Braeden Charlton, one of the study's authors at Vrije University in Amsterdam.
The tissue samples from long COVID patients also revealed severe muscle damage, a disturbed immune response, and a buildup of microclots.
"This is a very real disease," says Charlton. "We see this at basically every parameter that we measure."
People against piracy fail to realize that no, I can’t just ‘buy it.’ They stopped making DVDs and Blu-Rays. They’re barely offering digital copies for download. I am not spending money I could use for food or bills to pay for a subscription service just so I can always have access to a beloved piece of media. Especially not when the service will remove media on a whim without concern for how the loss of access to that piece will make its artistic conservation nigh impossible.
For example, I recently learned that Disney+ had an original film called Crater. It’s scifi, family friendly, and seems cool - I would love to buy it as a holiday gift for my little brother! But: it’s exclusive to D+ and THEY REMOVED IT LITERALLY MONTHS AFTER ITS RELEASE.
The ONLY way I can directly access this film is through piracy. The ONLY available ‘copies’ of this film are hosted on piracy websites. Disney will NEVER release it in theaters, or as something to buy, and it may NEVER return to the streaming service. It will be LOST because we aren’t allowed to purchase it for personal viewing. If I can’t pay to own it, I won’t pay for the privilege of losing it when corporate decides to put it in a vault.
love when ppl defend the aggressive monetization of the internet with "what, do you just expect it to be free and them not make a profit???" like. yeah that would be really nice actually i would love that:)! thanks for asking
@staff if you [change] the [design] of the fucking [dashboard] i will kill you
edit. i want it on the actual post that i am not actually making a de-th threat against the staff. that's shitty. the caption quotes the fucking costco hot dog meme, which i originally said in the tags. if any staff member sees this please do Not take it personally
Oh look, it seems everyone has been opted into the unfortunate "experiment" now. For everyone who has been blissfully using the old UI up until now, welcome to hell :)
Do you not like hell? Do you want to leave and crawl back up into the sunlight of the old UI? Well, have I got a link for you! A beautiful tumblr user (who is not me) has gone and fixed things beautifully for you already: https://github.com/enchanted-sword/dashboard-unfucker
You will need to have Tampermonkey installed on your browser of choice, and once that's done, just go to the github link above, and peruse the readme to install. And voila! You have your old dash back!
The authors of XKit Rewritten said during the experiments that at the time, since this was an "experiment" they weren't going to implement anything to revert to the old UI (although who knows if they'll do it now). And the dashboard unfucker has worked beautifully enough for me to where I genuinely couldn't tell if they had ended the experiment or not.
As a leftist Jew who believes strongly in the cause of dignity and freedom for the Palestinian people, and that Israel has abused them, I am begging fellow leftists to understand that real life is not a comic book. A government being “the bad guy” in a situation does not automatically make anyone who opposes it “the good guy”.
Hamas denies the Holocaust. Hamas disseminates the Protocols of the Elders of Zion—the conspiracy theory it paints is what they mean by “Zionist”. Hamas forbids foreign aid educators from teaching human rights to Palestinians, and claims that even teaching that the Holocaust happened is a war crime. Hamas has written the aim of annihilating Israel (the country and its people) into its charter—the mass slaughter and violent expulsion of 7 million Jews from the land is written into its laws.
There is no crime any state could ever do that would justify any of that; there is no act of state repression that could ever make it acceptable to side with the organization spreading Nazi pamphlets and Holocaust denial.
Oppose Bibi Netanyahu. Oppose Israel’s far-right, authoritarian government. Oppose Likud’s policies. Oppose its violence against Palestinian civilians. That isn’t antisemitic. But Hamas is—verifiably, beyond a shadow of a doubt, to its core—antisemitic. Its portrayal of Israeli Jews as blood-thirsty, child-killing master manipulators that control international media and finance is antisemitic. Its insistence that Palestinian freedom necessitates the death & expulsion of Jews from the land is antisemitic. Its redefinition of “Zionism” as a pejorative to mean genocidal Jewish/Israeli Supremacy is antisemitic.
Supporting the Palestinian people in their plight is a noble and loving goal; please never stop that. But do not let Hamas co-opt that into excusing or denying their rampant antisemitism and war crimes.
probably time for this story i guess but when i was a kid there was a summer that my brother was really into making smoothies and milkshakes. part of this was that we didn't have AC and couldn't afford to run fans all day so it was kind of important to get good at making Cool Down Concoctions.
we also had a patch of mint, and he had two impressionable little sisters who had the attitude of "fuck it, might as well."
at one point, for fun, this 16 year old boy with a dream in his eye and scientific fervor in heart just wanted to see how far one could push the idea of "vanilla mint smoothie". how much vanilla extract and how much mint can go into a blender before it truly is inedible.
the answer is 3 cups of vanilla extract, 1/2 cup milk alternative, and about 50 sprigs (not leaves, whole spring) of mint. add ice and the courage of a child. idk, it was summer and we were bored.
the word i would use to describe the feeling of drinking it would maybe be "violent" or perhaps, like. "triangular." my nose felt pristine. inhaling following the first sip was like trying to sculpt a new face. i was ensconced in a mesh of horror. it was something beyond taste. for years after, i assumed those commercials that said "this is how it feels to chew five gum" were referencing the exact experience of this singular viscous smoothie.
what's worse is that we knew our mother would hate that we wasted so much vanilla extract. so we had to make it worth it. we had to actually finish the drink. it wasn't "wasting" it if we actually drank it, right? we huddled around outside in the blistering sun, gagging and passing around a single green potion, shivering with disgust. each sip was transcendent, but in a sort of non-euclidean way. i think this is where i lost my binary gender. it eroded certain parts of me in an acidic gut ecology collapse.
here's the thing about love and trust: the next day my brother made a different shake, and i drank it without complaint. it's been like 15 years. he's now a genuinely skilled cook. sometimes one of the three of us will fuck up in the kitchen or find something horrible or make a terrible smoothie mistake and then we pass it to each other, single potion bottle, and we say try it it's delicious. it always smells disgusting. and then, cerimonious, we drink it together. because that's what family does.