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27.10.2020 » im gonna keep it real with you chief, online classes? not going well. motivation? none. focus? none. internet connection? shit. hotel? trivago. but at least the leaves outside are pretty.

asteristudy
asteristudy
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I love psychology so much,truly.I adore the subject so much and it is something I genuinely want to go ahead with and yes it has its flaws i get it but the potential i see in it is so fricking exciting to me! :) It used to make me so sad to hear people tell me that its one of the most useless degrees and i dont know man ‘useless’ is subjective :) so fuck you if you’re someone who bashes psych major students on their choice of learning.

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I keep seeing posts about how to prep for a study session by first cleaning everything, washing your face, making a snack, etc etc etc. That may totally work for some people, but for me it’s a way of procrastinating. And on top of that in doing all this prep work I build up this Major Perfect Study Session ™ in my mind so that when I sit down at my clean desk with my snack and my clean face and everything else, I’m either distracted or way too overwhelmed with the pressure to live up to this super high standard in my studying. 

Just wanted to put it out there that if that works for you, great, go for it. But I think it can be great to just seize the tiniest urge to study or even the feeling of “I could probably tolerate focusing right now” and sit down, right on the spot, and go for it. However far you get is awesome! The same holds true for other things like chores, and for me especially, working out. Since everything is shut down and I work out at home, I just get up and start as soon as I get the thought “I could stand to move around a bit right now.” If I start worrying about what sports bra to wear, what protein snack to prepare in advance, etc. I immediately become distracted as by brain jumps on the Procrastination Opportunity, and end up never working out.

Do what works for you. Learning at a messy desk, without a snack, for only fifteen minutes is infinitely better than getting overwhelmed at a clean desk or distracted by your snack, and not learning anything.

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“When I was one-and-twenty

I heard a wise man say,

‘Give crowns and pounds and guineas

But not your heart away;

Give pearls away and rubies

But keep your fancy free.’

But I was one-and-twenty,

No use to talk to me.


When I was one-and-twenty

I heard him say again,

‘The heart out of the bosom

Was never given in vain;

’Tis paid with sighs a plenty

And sold for endless rue.’

And I am two-and-twenty,

And oh, ’tis true, ’tis true.”

A.E. Housman, When I was One-and-Twenty (1896).

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10:00pm — Today, I went through 3 chapters and took notes. I work full time (luckily remote right now) so there’s less on weekdays and more on weekends.

I had originally planned my exam for 11/30, but decided since my state doesn’t have continuous testing yet, I should use all the time I possibly could so I could have a solid chance of passing on the first go. 

Right now, I am reading through each module and take notes. I’ll combine these notes at the end to make a study guide and run through MCQs. I feel like this is the best way for me to really retain all the information in this section.  

That’s it for today.  Goodnight! 

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The endocrine system physiology


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Part 4 (last part)

In this chapter we’re going to talk about:

1. Thyroid Hormones.

2. Insulin & Glucagon.


  • Thyroid Hormones:
  1. T4 or Thyroxine
  2. T3 or Triiodothyronine
  3. Calcitonin.
  • T4 & T3 :

T4 and T3 are tyrosine based hormones. Produced by the follicular cells (thyrocytes).

Synthesis:

Iodide (I-) is taken from the bloodstream by follicular cells to the colloid where it gets oxidized to iodine (I) then it combines with thyroglobulin to form MIT (monoiodotyrosine) and DIT (diiodotyrosine) .

Two DIT molecules combine to form T4 while MIT & DIT combine to form T3.

Iodinated thyroglobulin is transported back to the follicular cells and is cleaved by lysosomes.

T4 & T3 are then released into the circulation through MCT transporter.

Regulation:

TRH ➡ TSH ➡ THYROID ➡T4 & T3

➡ By:

⏫Iodide pumping

⏫ Iodination

⏫Thyroglobulin synthesis.

⏫ release of thyroid hormone.

T4 & T3 bind in the plasma to plasma proteins such as:

TBG or Thyroxine binding globulin

Albumin

Transthyretin.

The bound form is the inactive form. While free T3 & T4 form the active form that works on cells.

Note that inside the cell T4 is coverted to T3 by 5-Iodinase.

Effects:

⏫ Basal metabolic rate.

⏫Activation of sympathetic nervous system.

⏫long bone growth

⏫Hair follicle growth

Regulation of body temperature & weight.

Brain development.

  • Insulin:

Is a peptide hormone produced and secreted by Beta cells which are cells in the islets of langerhans

Synthesis:

Single polypeptide (preproinsulin) ➡ proinsulin (which has 3 chains : peptide A, peptide B and peptide C in between.

Proinsulin gets cleaved on two positions leaving the C chain alone (AWW :-( )

Two disulfide bonds connect The B chain and the A chain to form INSULIN

Effects:

⏬⏬ Blood sugar levels.

How :

In the liver:

Activates the formation of glycogen

(glucose ➡ glycogen)

In adipose tissue:

Activates glycolysis

In skeletal muscles :

stimulates amino acids and glucose uptake into muscle cells ➡ protein production and muscle growth.

Inhibites:

▶ Gluconeogenesis

▶ lipolysis.

Glucagon:

A hormone produced by alpha cells which are cells in the islets of langerhans.

Works by ⏫⏫ blood suger ▶ in situations like: fasting.

And it does that by:

▶ activation of gluconeogenesis & glycogenolysis

▶ activation of lipolysis.

Glucagon is a catabolic hormone which means it promotes the breaking down of large storage molecules inside certain tissues into small energy molecules in the blood.

Glucagon stimulators:

▶ low blood suger

▶ adrenaline

▶ cholecystokinin


Glucagon inhibitors:

▶ high blood sugar

▶ somatostatin

▶GH


Part 1

Part 2

Part 3

💒- 💒-💒-💒-💒-💒-💒-💒


Hello 🌸🍃

With this we’re done with a good part of endocrine physiology!Next, we’re going to start with clinical cases and diseases related to the endocrine system (aka we’re gonna get serious SERIOUS xD) I hope you find this helpful in reviewing or studying ☺

Thank you so much🌸🍃

Marie🌸

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october 26th, 2020

helloooooo, never actually updated you guys since my last post and a lot of things ended up happening, but everything is getting better now bc after every storm comes a rainbow!

📖 and, to better my week i made scones!! definitely the most important part of my week lol, food! now i’m back to the routine of studying since i spent the entire weekend completely unfocused from the school work and all those colorful papers full of knowledge, and now we’re headin to our next stop, geography test!

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