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#pancreatic cancer
rebirthgarments · 10 days
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TW: Chemical w-rfare, Ab-rtion
Urgent Ask to evacuate Nara, a 🍉 disabled woman with MS who also has pancreatic cancer due to chemical w-rfare.
Support by financially contributing to her @FedUp4Palestine vetted funhnd-raizer (that I personally vetted): givebutter.com/NaraMedicalAid
+ resharing/ reposting this post!
I, Sky Cubacub- a Fed up 4 Palestine team member, have been in direct contact with Nara to get to know her and her story more over the past few days. We have become fast friends due to so many overlapping symptoms of our disabilities. Nara’s story caught my eye because I have post-viral ME/CFS which many times is a precursor to MS. I really want my disability community to show up for her to get this campaign funded that is so close to my heart so that she can continue medical treatment.
We have chatted extensively! During our chats, I found out from Nara that she had not previously had health issues until she was exposed in the white phosphorus attack in 2008. The long lasting damage and effects of phosphorus continue to compound and become more and more disabling to this day, even after 16 years.
Here is her story in her own words (edited for clarity):
“Hi I'm Nara,
I'm a cancer and multiple sclerosis patient. I need treatment, examinations, and follow-up on a regular basis, but the hospitals in which I used to follow up were bombed and the other one was turned into military barracks. All I need now is to leave Gaza for treatment, preserve my life, and live with my family in peace.
We're a family of 4, including my 12 and 7 year old children.
I had been diagnosed with a tumor in the pancreas as a result of inhaling phosphorus in a previous war. A couple years after being exposed to phosphorus, I became pregnant, and the fetus was pressing on the tumor, which drew the doctor’s attention to the cancer. My fetus was emergency aborted, and the spleen, 80% of the pancreas, and part of the small intestine were removed. I complained every now and then of a lot of pain as a result of the removal of part of the pancreas. I was having follow up care in the Turkish Friendship Hospital for hematology and tumors. But since the beginning of October, I have not been able to follow up because the hospital has turned into a military barracks.
The remaining part is talking about multiple sclerosis:
In 2018, I was diagnosed with multiple sclerosis. I had many complications, such as inflammation of the seventh nerve in the eye, the inability to walk with balance, movement with difficulty, and many symptoms. I was then required to take 12 injections every month and many medications and vitamins. I was following up at the Nasser Medical Complex in Khan Yunis, but unfortunately the hospital was out of service due to the war. So for a long time I have not received any injections. MS is truly difficult and it controls my life completely, and the attacks occur in many and varied ways.”
A note about her breathing apparatus:
Because people in displacement have to wait in long queues and pay to use the bathroom, Nara had started to restrict her water intake because of a UTI she never has been able to heal from. This has created a problem with raised levels of potassium, so doctors have placed her on oxygen for fear of the potassium affecting her heart.
Goals
she needs at least $15,000 to evacuate
2 adults at $5,000 each
2 children at $2,500 each
this price is subject to increase due to the cost of registration for evacuation continuing to go up
The other money will go to the cost of treatment and living costs.
Nara chooses to stay anonymous because she has had to mask her disabilities so much that only her family knows about her MS and Cancer, so we have not linked her instagram, but we are in direct contact with her and can verify that she is who she says she is! Because of this, she cannot promote her own fundraiser, so it is our job to collectively do it for her!
[Image Description: a digital illustration by @k8deciccio of Nara, a Pal-eh-stienian woman wearing a black hijab/outfit with purple highlights. She has a breathing apparatus that is bulbous that goes in her nose. Text Reads: Help Narawith Cancer and MS Treatment, She Must Evacuate with her family of 4. $30k goal givebutter.com/NaraMedicalAid . There is a QR code in the bottom right corner that goes to her support link. The @FedUp4Palestine logo is in the top left corner.]
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mindblowingscience · 2 years
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A new treatment completely eliminated pancreatic cancer tumors in 80% of mice across several model types, including those considered the most difficult to treat, a new study shows.
Researchers say the new approach, which combines traditional chemotherapy drugs with a new method for irradiating the tumor, is the most effective treatment for pancreatic cancer ever recorded in mouse models.
Most mouse trials consider simply halting growth a success.
[...]
“We did a deep dive through over 1,100 treatments across preclinical models and never found results where the tumors shrank away and disappeared like ours did,” says Jeff Schaal, who conducted the research during his PhD in the laboratory of Ashutosh Chilkoti, professor of biomedical engineering at Duke University.
Continue Reading.
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remembertheplunge · 5 months
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This Zoe thing: it's impossible to describe in words
May 7, 2023. Sunday. 8:48pm
Home. 
Thank God
Motel living gets old.
There is such a feel of lack of privacy.
Talked with neighbor Alice on my return from Chico around 6pm this evening.
Regarding Zoe’s impending death, she said “It will be quick. It will happen soon.”
She will pick up my mail and put the trash cans up while I’m gone Wednesday to Sunday.
She said to check on donating Zoe’s body for scientific research. They pick the body up. Cremation is free.
This is ghastly to discuss. Horrible. But, it’s apparently a reality. I told Zoe today that I still don’t quite believe that she will die.
She told Javiar, her neighbor, that she wanted nothing that would extend or prolong her life.
Zoe wrote journals! I never knew. I glanced in one and saw that it was dated 1987. I brought 5 of her journals home. I will bring the rest next trip.
She said “Don’t get mad about what I wrote about you.” 
I said “I never would, that’s what journals are for.”
I brought home Red Fred, Lovable Pinky and the painting I did of LE and Anna’s house in Cassie Loving’s art class in 1983!
When I hesitated taking the painting, she said “Take it, I’m dying.” She said to take things now, they may disappear later.
Letting her precious things go is a sign that she is dying.
The first blog re: Zoe’s illness and impending death came out today.
It got 5 likes.
Driving away from Chico about 1pm, I cried.
I played on Apple Play Greg Brown’s " Spring Wind” in which one lyric is “A Spring wind  blew my list of things to do away.”
And a song I’ve never heard before Van Morrison’s “Into the Mystic”
And Phil Ochs. “Changes”.
This feels raggedy and horrible.
It’s so hard not to feel guilty about all that I could have done that I didn’t through the years for Zoe.
So, I breath in healing.
9:55pm
I tried to sleep. I’m vey anxious. 
Such odd times. This Zoe thing. I’ve never felt like this before..
This kind of uneasiness.
It’s impossible to describe in words.
End of entry
Notes:
My sister, Zoe, died May 14, 2023. 
I live in Modesto, California. Chico, where she died, is a 4 hour drive north from here. 
LE and Anna were my father’s parents. The house I painted was their 1926 home they had built in Lincoln Nebraska. That is the city I was born in in1955.
Alice, my neighbor is a retired nurse. She also said on May 7 that my sister’s death would be a rough ride. It was. Zoe died of pancreatic cancer.
Red Fred and Lovable pinky were stuffed animal dog’s that we had as children.
Cassie Loving was my art instructor and later close friend in Placerville, California. I began practicing law in Placerville in the early 1980’s.
Walking up to the court house Monday May 8 here in Modesto, I got the call from Zoe that the Doctor earlier that day said that she had weeks to live. 
I returned to Chico Tuesday May 8. 
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bpod-bpod · 2 months
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Tumour Environment Effects
Combined immunotherapy (GVAX + anti-PD1) and targeted radiotherapy for pancreatic cancer not only promotes anti-cancer T cells but also immunosuppressive macrophages – insight for skewing therapy towards greater anti-tumour effects
Read the published research article here
Image from work by Junke Wang and Jessica Gai, and colleagues
Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Image originally published with a Creative Commons Attribution 4.0 International (CC BY-NC 4.0)
Published in Science Advances, February 2024
You can also follow BPoD on Instagram, Twitter and Facebook
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amft · 2 months
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Last November we had to put down our precious family kitty girl, Dorothy. And that night and the days to follow, we had multiple conversations with Loretta about death. Whenever she would ask if this person or that person (including us, our family and friends) and if this toy or that toy and this animal or that animal was going to pass away, we’d always answer seriously and honestly.
And we continue to occasionally have these conversations with her, every time she asks. Sometimes they’re brief. Sometimes they upset her. Sometimes half way through an explanation she gets distracted by Cheerios.
Tonight she told me, “Mommy, I don’t want you to pass away.” I pause. I let out a slight sigh. And I say “Baby. I will pass away someday. But I’m going to be here with you as long as I possibly can. And when I can’t be here with you, I’ll be in the stars like Dorothy. And I’ll be with you in your heart.” She asks, “Will you hug my heart?” “All day, every day.”
A few weeks ago when we got news that my mother’s cancer had spread, I remember having similar thoughts that Loretta had tonight… Mommy, I don’t want you to pass away. We don’t know where this new path is going to lead us. I can’t fall down the rabbit hole of “what if’s.” But I just have to give myself the same advice we’ve been giving her. I have to tell myself… she’s here as long as she can be. And that’s all we’ve got. So I’m going to enjoy it for as long as I can.
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ranwing · 3 months
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New ink
I've been wanting a new tattoo for quite awhile now and wanted to do one as a memorial to Mom. My niece came up with the idea of copying Mom's butterfly tattoo (she had taken a picture of it before Mom died) on the back of our necks. Fantastic idea. She did hers a few weeks ago and it looked great. So today I went under the needle.
Unfortunately Mom's tattoo was very old and sun damaged so it was hard to really see all the details and my artist asked if we could make a few small alterations that would fill in the lost details. That was fine, as the basic design was the same and it had to be purple (both Mom's favorite color and the color for pancreatic cancer awareness.
So now I have a piece of Mom permanently etched on my skin. And I know that she still has my back.
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lecameleontv · 2 months
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Le 04 mars 2024, le producteur-scénariste Juan Carlos Coto a participé à une levée de fond caritative pour la Recherche contre le Cancer du Pancréa, maladie qui a emporté son frère aîné, Manny Coto.
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Une émission sur la franchise Star Trek permetait d'animer l'évènement, qui se poursuivra le 27 avril 2024 avec l'organisation de vraies courses à pied caritatives pour continuer à sensibilier/récolter des fonds.
En savoir plus : Purple Stride - Taking Steps Together to End
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Un clin d'oeil à son frère avait été fait dans l’Ep. 3.17 de la série Le Caméléon (V.O. : The Pretender).
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Pour information, l'acteur Harve Presnell est également décédé de cette même maladie.
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sources : @fsfpopcast et @brasstab.
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cbirt · 1 year
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Pancreatic Cancer and Drug Resistance: Researchers Identify Key Metabolic Regulators
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Drug resistance can be countered only by interrupting the adaptive measures taken by the cells to deflect the drug action. Scientists from the School of Pharmacy and Pharmaceutical Sciences, University of Buffalo, performed an extensive study through proteomic analysis that identified key regulators driving the resistance against Gemcitabine, the principal chemotherapeutic against Pancreatic Adenocarcinoma. The study also mentions viable pathways and protein targets onto which therapeutic efforts could be directed to better improve the drug efficacy.
Gemcitabine, first marketed under the brand name Gemzar by Eli Lilly, is an antimetabolite capable of retarding tumor progression and promoting apoptosis by inhibiting DNA synthesis. On its uptake into the tumor cell, the compound is phosphorylated to form gemcitabine monophosphate, which acts as the precursor for its diphosphate and triphosphate forms. The diphosphate interacts and inhibits the ribonucleotide reductase (RNR) complex that maintains the nucleotide levels within the cell, while the triphosphate is a structural analog of deoxycytidine triphosphate(dCTP) and masquerades around as dCTP on its synthesis. In a nucleotide deficient state caused by gemcitabine diphosphate, it competes with dCTP for incorporation into the elongating DNA strand. On achieving this, it causes chain termination, ultimately dismantling the DNA synthesis machinery of the cell.
Continue Reading
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mieteve-minijoma · 11 months
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My father is losing his battle with cancer and my heart is absolutely broken. He is doing hospice care at home and I made the trip back home to be with him. We are limited on funds since my hubs and I are both disabled so we have started a GoFundMe.
Please, if you can donate (even if it's just a few dollars), we would much appreciate it. We aren't sure how long we'll be here and it would help us and also my stepmom so she doesn't have to worry about food while we are here.
Love you guys 💜
If you want to send by Venmo or Cash app, I'll list them here:
Venmo: @Bina-Eubie-2006
Cashapp: $Pappy0820
https://gofund.me/8409d3b7
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thefoxinator · 8 months
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azukilynn · 8 months
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Another member of the TWC has gone to the other side. Max Mundan, you helped me get my footing when I first started blogging here, and for that I will be eternally grateful.
Your poetry, so honest and raw, made quite an impression on me.
It is filled with things both heartbreaking and wondrous.
I'm so glad we got to connect beyond this platform. You lived an amazing and varied life from Africa and back again with your lovely wife.
I've been thinking about you both every day and will always remember you with fondness.
Love and light to you and yours.
Always.
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hum-tittle · 26 days
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Being a caretaker for your parent as they’re at the end of their life it such a weird form of grief.
Not only am I losing my dad, but it feels like I'm losing "my child," too.
I've been feeding him, cleaning him, planning events for him, protecting him, and anything he needed help with.
He's still my dad, but our relationship changed, and I was caring for him like he did for me when I was a kid.
I know other caretakers probably have a better way to describe this, but it is all still fresh. He was given his terminal diagnosis just a few days ago. Even though it feels a lifetime ago.
(Also, please note that if you send sympathy, it's appreciated, but I probably won't respond. I don't have the emotional or mental capacity at the moment 💛)
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deepest-shake · 2 months
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please help the lim family:
Hi, I'm Lam and I'm fundraising for an old friend of mine from the Lim family. Three years ago, during the COVID-19 pandemic, the Lim family fought hard and long to overcome the challenges they face and even though its really tough on them, they found happiness in being together despite the challenges they are facing. However, their fragile happiness was shattered when tragedy struck mercilessly.
Mr. Lim, the pillar of the family, fell victim to a heartless scam by an old friend of his and ended up taking his own life. It left the family with a huge debt to deal with, and they didn't even have the chance to properly mourn and say goodbye to him during his last moments. His death plunged the Lim family into grief and despair, leaving them heartbroken.
The news of Mr. Lim's death hit the family hard, and they've been working days and night to pay off the debt ever since. After three long years of struggle, they finally managed to clear it. But just when they thought things might get better, Mrs. Lim collapsed from exhaustion. And then came the devastating blow – she was diagnosed with pancreatic cancer. Their only daughter had to quit school to pay off Mrs lims treatment and their next payment is due soon. Mrs lims condition is getting worse and worse as each day passes.
It's been one blow after another for the Lim family and they really really need help to cover the costs of the treatment to save her life. It's a heartbreaking situation, and they could really use all the support they can get right now. We are hoping to raise 30 000 for their treatment as soon as possible. Thank you so much for your help.
Any help will be greatly appreciated.. we thank you so much for your help.. please click the link to show support.. thank you so so much.
Please help.. this is the link for the donation platform in gofundme... all fund I go directly to the lim family bank account..
Link:
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bpod-bpod · 9 months
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Seeing Low Oxygen
Visualising tumour cell oxygen deprivation (hypoxia) in a living mouse model with pancreatic cancer using a new fluorescence microscopy approach
Read the published research paper here
Image from work by Timothy Samuel and colleagues
Princess Margaret Cancer Centre, University Health Network, Toronto, Canada
Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
Published in Science Advances, June 2023
You can also follow BPoD on Instagram, Twitter and Facebook
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amft · 8 months
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I’m not normally one to make posts like these. But… this is close to my heart.
This past April my family and I decided at the last minute to register and attend the Dallas-Fort Worth - Pancreatic Cancer Action Network (PanCAN) PurpleStride event in Dallas, to show support for our precious mom and others still fighting the good fight, those who kicked cancer’s ass and those who fought hard until the very end. We didn’t know what to expect when we showed up - and man were we blown away. We spent a morning surrounded by so many wonderfully encouraging and inspiring people. And because we loved it so much, we’ve registered to walk next year! And this time, we’re going as a team!
I created the team, Can’t spell Yaya without YAY! And if you feel so inclined, you can make a donation.
Between you guys and me… I didn’t think we’d still have my mom with us today. When she was first diagnosed back in 2020, we had a lot of information thrown at us along with our own personal research… and the odds didn’t seem to be in her favor. But! She’s here. And thriving. And every day I get to wake up in a world where my mother still exists is a great day.
Thank you all for always allowing and accepting my random ramblings. 💜
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hopeless--heroine · 9 months
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Hey y’all, this isn’t something I’d usually post about or ask but I’m really struggling and can’t catch a damn break. I’m honestly so exhausted from everything I’ve dealt with the last few years and it’s be wearing me down, I feel like I’m suffocating almost. From having pancreatic cancer last year, ongoing physical/mental/ and emotional health issues, car issues and my family/dogs health issues. Having to spend almost 900 last week I didn’t have on my dog who got very ill; I couldn’t bare to lose my best friend who helped me through cancer. Having my tire blow out on the freeway yesterday almost smashing me into the side of a semi truck ending my life. If any one can/is able to help me out, even just a little bit I’d greatly appreciate it. Please share this around. Lots of love from me to you. Stay safe and be king 🖤💗#cancer #pancreaticcancer #survivor #help #struggling #frenchbulldog
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