#parkinsons

[mindblowingscience]

A colossal study has revealed a variation of a gene involved in an immune response has been secretly giving protection to the billions who carry it from Alzheimer's and Parkinson's disease. Known as DR4, the variant, or allele, is part of a family of genes that normally help our immune system pinpoint and destroy foreign invaders, like bacteria and viruses. "In an earlier study, we'd found that carrying the DR4 allele seemed to protect against Parkinson's disease," says psychiatrist and geneticist Emmanual Mignot from Stanford University in the US, the institution that led the study. But Alzheimer's and Parkinson's are distinct conditions with different pathological biomarkers in the brain – Lewy bodies for Parkinson's, and abnormal tangles of a protein called tau in Alzheimer's. Discovering DR4 as a common factor was astounding.

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#science #stem #biology #medicine #health #parkinsons #alzheimers #genetics

[theladyflash]

So on top of dealing with being sick from post covid symptoms in the last year, I lost my mother 8 months ago after being her caregiver for a longtime. Even though she was sick mentally, physically including parkinsons for a while, the way we lost her was really awful and kind of traumatising. There's a lot to unpack with therapy but I'm trying to work through it every day. I'm trying to find small ways to keep her with me and embrace some of the things she loved. One of the things she really, really loved was the show Criminal Minds. She watched every single episode and would pretty much reiterate ever one to me (it was kind of annoying sometimes to be honest lol). Especially her love for the character Spencer Reid and his storyline with his mother. I know almost everything about his characters back story despite never ever watching it. She use to try to get me to watch it with her constantly, but I was either busy or watching something else. Even though I know I shouldn't feel guilty because I did spend a lot of time with her every day and being a parents caregiver is a very tough thing. A big part of my life was basically being a mother to my own mother. Which is a heavy thing on your heart, soul even when no one is to blame. I don't miss my ill mother, she wasn't easy because living with serious illness sometimes changes a person. I do miss my mother, my real mother who was beautiful, funny and so smart every day. And even the things she loved. So a week or so ago I started binging the show so maybe I could find out why she loved it. I'm on the tail end of season 3 and really enjoying it. I'm sorry I never got to enjoy it with her, I know she would have loved discussing each episode during commercials. And fine, mom my neurodivergent butt likes Reid too ok?

❤❤❤❤❤

#criminal minds #spencer reid #neurodivergent #mom #mother #loss #death #parents #television #parkinsons #mental illness

[apas-95]

x

#cuba #alzheimers #parkinsons

[spookietrex]

Had a neurologist appointment today that went really well. It was nice to just be...heard for once. I started in on my "my doctors aren't listening to me and are making things up" speech and she started to cut me off until I cut her off and explained that a certain hospital near us had actually documented in my medical record that I'd thrown up on purpose. (I didn't. They'd asked about nausea but unfortunately I'm dissociative in the hospital...especially if you're trying to involuntarily hospitalize me) and she stopped. She documented my symptoms and referred me to another provider who can actually help evaluate me for Parkinsons because my symptoms are more than just functional neurological disorder and I'm tired of being dismissed. She actually watched my videos of my tremoring and my muscles convulsing involuntarily and it switching sides.

#my journey to find healthcare that doesn't hate me #chronic health issues #chronically ill #chronic pain #chronic illness #chronic fatigue #chronic fatigue syndrome #hypermobile eds #fuck you eds #eds zebra #eds #hypermobile ehlers danlos #hypermobile joints #hypermobility #living with pots #fuck you pots #potsie #pots #post traumatic stress disorder #functional neurological disorder #fnd #seizure like activity #dystonia #parkinsons #my medical record is just my doctors telling me i'm lying #medical records #medical trauma #what my doctors think i sound like #my doctors hate me #actuallymentallyill

[bpod-bpod]

Conversation Starters

Neurons communicate with chemicals – bursts of neurotransmitters which pass signals from one cell to the next. While the brain’s millions of neurons may look a little chaotic, their chemical chatter is in a fine balance that changes with age and disease. Normally, dopaminergic neurons squirt a neurotransmitter called dopamine into different brain areas, influencing processes such as movement, reward and motivation. Here researchers grow human dopaminergic neurons (highlighted in orange) from stem cells in a dish. With so many important roles in the brain, they investigate how the cells deteriorate in Parkinson’s Disease – specifically, how a toxic chemical called alpha-synuclein (which builds up in Parkinson’s) affects the cultured cells. The next step is to see if new drugs can slow down or stop alpha-synuclein, staving off symptoms.

Written by John Ankers

Winning image by Nick Gatford of the Nuffield Department of Clinical Neurosciences

Image category of the University of Oxford's Department of Biochemistry Centenary Scientific Imaging Competition

Image copyright held by Nick Gatford

Research published in Nature Communications, June 2021

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#science #biomedicine #neuroscience #reward centre #dopamine #parkinsons #brain #neurostransmitter #immunofluorescence

[metalheadsforblacklivesmatter]

-fae

#disability #disabilities #medical marijuana #parkinsons

[dbaydenny]

My brother carved peace

in wild ducks, graceful swimmers,

perfect placed feathers,

details sublime, realistic

until Parkinsons took him.

.

D W Eldred

#poetry #tanka #Parkinsons #my brother #duck carving

[randomrichards]

STILL: A MICHAEL J. FOX MOVIE

Fame’s impact on Fox

How he lived with Parkinson’s

Life never stood still

#still #a Michael j. fox movie #random richards #poem #haiku #poetry #haiku poem #poets on tumblr #haiku poetry #haiku form #poetic #apple plus #apple+ #documentary #michael j fox #parkinsons #tracy pollan #davis guggenheim #Youtube

[daltongraham]

Just finished watching this. Very interesting, highly rec.

If you don't already know, he has Parkinson's and runs a foundation to study treatments and cures. You can participate in a study! It is intended to run for your lifetime (you can bow out any time) to gather data. You don't have to have Parkinson's to participate. If you are interested in helping, here's the link. The questions are fun! Kind of like doing 23andme research. Took me about a half-hour total to answer (you can do it in little bits; the surveys are from 1-5 minutes to fill out) You can opt out of any questions you think are too personal. I have no idea how my participating will help--I have essential tremor but not Parkinson's--but who knows, maybe it will! After all, you need negatives as well as positives in research.

#michael j fox #parkinsons #Youtube

[loubie364]

The tune up

Kirstenbosch Botanical Gardens The photo is of one of the centenarian trees at Kirstenbosch – unfortunately I failed to record what type of tree it is. I love looking up into trees it is like nature’s kaleidoscope. This tree is over a 100 years old, I am always amazed by this, and I imagine the tales this tree could tell. This tree involved a fair uphill walk and if you read further, you will see…

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#deepbrainstimulation #Dua Lipa Moves #Humour #Kirstenbosch #lifewithpd #Parkinsons #pd #riverdance #Rugby #Trees

[mindblowingscience]

Electrical deep brain stimulation (DBS) is a well-established method for treating disordered movement in Parkinson's disease. However, implanting electrodes in a person's brain is an invasive and imprecise way to stimulate nerve cells. Researchers report in Nano Letters on a new application for the technique, called magnetogenetics, that uses very small magnets to wirelessly trigger specific, gene-edited nerve cells in the brain. The treatment effectively relieved motor symptoms in mice without damaging surrounding brain tissue.

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#Science #Biology #Neurology #Parkinsons #Nanotechnology #Genetics #Brains

[highlifestyleindia]

Actor Michael J. Fox accepts honorary Oscar for Parkinson's advocacy

Michael J. Fox, an actor best known for his roles in the "Back to the Future" films and the 1980s TV comedy "Family Ties," earned an honorary Oscar on Saturday for his advocacy efforts that have helped generate $1.5 billion for Parkinson's disease research.

At the age of 29, Fox was diagnosed with Parkinson's, a neurological condition that results in tremors and other symptoms. Later, he stopped acting, and in 2000 he established the Michael J. Fox Foundation for Parkinson's Research to support the effort to find a treatment.

"It is humbling in the deepest way to stand here and accept your kindness," the Canadian actor said on stage at the annual Governors Awards, where an A-list crowd of stars including Tom Hanks and Jennifer Lawrence gave him a standing ovation.

Fox said the hardest part about his diagnosis was "grappling with the uncertainty" and that he had kept his diagnosis private for years because "I didn't know if an audience could laugh if they knew I was struggling."

The 61-year-old Canadian actor was presented with the Jean Hersholt Humanitarian Award by the Academy of Motion Picture Arts & Sciences' board of governors and was introduced by Woody Harrelson, a friend.

"He turned a chilling diagnosis into a courageous mission," the "Cheers" actor said.

Other recipients of the Governors Awards included prolific songwriter Diane Warren, whose songs have been featured in more than 100 movies.

Warren, 66, has been nominated for an Oscar for best original song 13 times but never won.

"I've waited 34 years to say this: I'd like to thank the Academy," Warren said to applause on Saturday.

Also honored were Australian director Peter Weir, known for films including "Witness" and "Dead Poets Society," and Euzhan Palcy, who became the first Black woman to direct a film for a major Hollywood studio with "A Dry White Season."

#michael j fox #woody harrelson #Oscars #Awards #parkinsons #viral #trending #followback #instalike #repost #instagram

[tremor-culture-is]

hello, darlings! I just wanted to share this:

It's a (fairly) long list of mobility aids and stuff of the sort, made specifically for essential tremor! Some might also be useful for those with arthritis or Parkinson's.

#not culture is #essential tremor #disability #disabled #neurodivergent #neurodiversity #parkinsons #parkinsons disease #arthritis #mobility aid #physical disability #disability awareness #assistive devices #assistive technology

[deanwinchestersgirl87]

Parkinson is a pain in the ass by itself but when you add neuropathy and arthritis and bipolar disorder to it I'm just really tired of doctors and being in pain and nobody to listen to me they just judge me and act like I'm a burden it's truly annoying.

#supernatural #jensen ackles #dean winchester #jared padalecki #samwinterchester #misha collins #castiel #parkinsons #arthritis #neuropathy #pain #bipolor

[bpod-bpod]

Another Vulnerable Population

Study of different cell types in Parkinson's disease-affected brains reveals, in addition to dopaminergic neurons, another type called RIT2 neurons that are vulnerable to Parkinson's-associated molecular changes

Read the published research article here

Image from work by Qian Wang, Minghui Wang and Insup Choi, and colleagues

Icahn School of Medicine at Mount Sinai, New York, NY, USA

Image originally published with a Creative Commons Attribution 4.0 International (CC BY-NC 4.0)

Published in Science Advances, January 2024

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#science #biomedicine #immunofluorescence #neuroscience #parkinsons #parkinson's disease #neurons #dopamine #brain

[banjolandsblog]

STILL: A Michael J. Fox Movie — Official Trailer | Apple TV+

#youtube #still #michael j fox #american horror story #real life #drama #parkinsons #trailer #documentary #indepth #true stroy