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bluecatears · 8 months
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These two need to talk
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foxglovecove · 3 months
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Tendo got a Polaroid for Christmas and made it everyone’s (see: Newt and Hermann’s) problem. He of course gave them all to the boys to decorate their new apartment.
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science-lover33 · 7 months
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🔬🌀Demystifying the Krebs Cycle: A Deep Dive into Cellular Respiration! 🌀🔬
Prepare for a thrilling journey into the heart of cellular metabolism! 🌟✨ Today, we unravel the intricacies of the Krebs Cycle, also known as the Citric Acid Cycle or Tricarboxylic Acid Cycle, a cornerstone of energy production in our cells. 💡🤯
The Krebs Cycle: Named after its discoverer, Sir Hans Krebs, this metabolic pathway occurs within the mitochondria and is a central hub in cellular respiration.
🔍Step 1: Acetyl-CoA Entry
Acetyl-CoA, derived from the breakdown of glucose or fatty acids, enters the cycle.
It combines with oxaloacetate to form citrate, a six-carbon compound.
🔍Step 2: Isocitrate Formation
A rearrangement converts citrate into isocitrate.
The enzyme aconitase facilitates this transformation.
🔍Step 3: Alpha-Ketoglutarate Production
Isocitrate undergoes oxidative decarboxylation, shedding a CO2 molecule and yielding alpha-ketoglutarate.
NAD+ is reduced to NADH in this step.
🔍Step 4: Succinyl-CoA Synthesis
Alpha-ketoglutarate loses CO2 and acquires a CoA group to form succinyl-CoA.
Another NAD+ is reduced to NADH.
This step is catalyzed by alpha-ketoglutarate dehydrogenase.
🔍Step 5: Succinate Formation
Succinyl-CoA releases CoA, becoming succinate.
A molecule of GTP (guanosine triphosphate) is generated as a high-energy phosphate bond.
Succinate dehydrogenase is pivotal, transferring electrons to the electron transport chain (ETC).
🔍Step 6: Fumarate Generation
Succinate is oxidized to fumarate with the help of the enzyme succinate dehydrogenase.
FADH2 (flavin adenine dinucleotide) is formed and transfers electrons to the ETC.
🔍Step 7: Malate Formation
Fumarate undergoes hydration to form malate, catalyzed by fumarase.
🔍Step 8: Regeneration of Oxaloacetate
Malate is oxidized back to oxaloacetate.
NAD+ is reduced to NADH.
Oxaloacetate is ready to initiate another round of the Krebs Cycle.
The Krebs Cycle - an intricate dance of chemical transformations fueling the cellular machinery of life. 🕺💃 Dive deeper into cellular respiration, where molecules tango to generate ATP, our cellular energy currency!
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📚References for In-Depth Exploration📚
Berg, J. M., Tymoczko, J. L., & Stryer, L. (2002). Biochemistry (5th ed.). W. H. Freeman. Chapter 17.
Voet, D., Voet, J. G., & Pratt, C. W. (2008). Fundamentals of Biochemistry (3rd ed.). John Wiley & Sons. Chapter 17.
Lehninger, A. L., Nelson, D. L., & Cox, M. M. (2008). Lehninger Principles of Biochemistry (5th ed.). W. H. Freeman. Chapter 17.
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womanofwords · 2 months
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STEM Kids Shenanigans (Chapter 28)
Chapter 28: Feral Newspaper Hound
Dante was avoiding Stephan. That guy had the nickname 'snake' for a reason. First he tries to spy on them with a bear, and now it seemed that he was blackmailing Melanie. Admittedly, Dante didn't like Melanie at all, but blackmail was still wrong.
The real question was what Melanie could possibly have that Stephan could use to blackmail her with.
Melanie was not well-liked, but she didn't seem to be hiding anything. Even when trying to disband the STEM club, she was weirdly honest about it. Maybe that honesty was carried over to other parts of her life, like when she was with Stephan. In his head, Dante whittled it down to three options.
Option 1: Melanie told Stephan a secret, and Stephan planned to use it against her.
Option 2: Stephan found something out about Melanie and was planning to use it against her if she didn't do as he said and wanted.
Option 3: Melanie and Stephan were involved in something together, and then Stephan decided to turn on her.
Stephan may have been one of Melanie's only friends, but Melanie wasn't Stephan's only friend.
Not by a long shot.
People constantly went in and out of the room and Stephan knew every last one of them. This was freaky.
He had to tell the others.
(PAUSE)
"So let me get this straight," Layla said, "Stephan has got friends basically everywhere and probably knows everyone's secrets. And you want to know what he is blackmailing Melanie about?"
"Yeah, pretty much," Dante said.
"I'm in. What do you need?" Angelo asked.
"You're not even going to question him?" Layla asked.
"I don't like Melanie, but I know she doesn't deserve to be blackmailed by Stephan," Angelo said.
"I also know that she'd never tell us," Layla said. "She calls us delinquents right to our faces and she'd think we're blackmailing her."
"Even though she's already being blackmailed?" Yujin asked. "How ironic."
"We still need to figure it out," Dante said.
"And while we're at it, we'll have to figure out how to do so without getting caught," Angelo said.
"Like what? Giving Stephan one of his own spy bears?" Dante asked.
"You know what, my neurodivergent friend?" Angelo said. "Yes. But not literally, of course. What do we disguise it as?"
"Something that he would accept without question," Yujin said.
"Until then, I'll see if there's anything more I can find out," Dante said.
(PAUSE)
Dante did more spying on Stephan, this time for interesting quirks. Stephan didn't seem to have anything interesting that he did. He was completely normal, except for being a lying snake of a person. Dante heard Melanie's footsteps, and quickly buried his head into his book.
"Delinquent," she hissed in his direction, as she went to Stephan.
This was gold. They were totally going to have an interesting conversation in there, and Dante would get to hear it himself.
"Is there anything else I can give you?" Melanie pleaded. "Please, I just want this to stop. I have money. How much do you want?"
"I don't care about money," Stephan told her. "This is the coolest thing I could ever have stumbled across. Really, Melanie Sainsbury doing-"
"That's enough, Stephan!" Melanie snapped. Stephan sniggered.
"That's only the tip of the iceberg, though. We both know that. Just wait until people see this. It'll be everywhere."
"No, no, no, please! I'll do anything, please!"
Stephan leaned forward and smirked. "Anything?"
"Yes, anything! Just please keep this a secret," Melanie begged. It truly tugged on Dante's heart strings.
"OK. You do what I want. Just don't complain when you don't like it," Stephan said. "Got it?"
"Got it," Melanie said. She scurried out, thankfully not noticing Dante a second time. After a few seconds, Dante left too.
That was wasted time, Dante thought. Now, we'll just have to wait and see like everyone else. How boring.
To read the other parts of this fic, see Masterlist.
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For any nerds out there who might not know (I’m looking at you Donnie kinnies)
The international championship for high school robotics started today!!! If you wanna watch some robots competing in a silly little game you can tune in to one of FRC’s livestreams on twitch today, tomorrow &/or Saturday!!! (Saturday’s the elimination rounds & finals so you’ll really want that one if you can)
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tomsvouge · 4 months
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What is this man on about 😂😂
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eirxair · 1 year
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Sakusa Kiyoomi is definitely a history nerd bc im a history nerd and ik how to spot one.
Subsequently Miya Atsumu is a science nerd bc im a history nerd and ik how to stay away from one
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whoisandyloam · 6 months
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silvertonguecynic · 6 months
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Is it me, or do galaxies resemble cells? 🤔
I mean, there's a nucleus (black holes) or sometimes a nucleoid, cytoplasm (nebulous dust), different celestial bodies resemble microbodies.... I could continue, but I'd rather hear others' opinions and / or comparisons
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taylor-ashely · 1 year
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montereybayaquarium · 8 months
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People who get excited about sunrises,
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sunsets...
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the moon...
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a sky full of stars...
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and deep connections...
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are our kind of people. ✨ 💙 🌊
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science-lover33 · 7 months
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"Delving Deeper into Glutathione: The Biochemistry Behind its Protective Powers"
Hello, Tumblr community! 🌿 Today, let's embark on an intellectual journey into the intricate world of Glutathione, a molecular marvel with profound implications for your body's defense mechanisms and overall vitality. 🧬
The Biochemical Symphony of Glutathione:
Glutathione, abbreviated as GSH, is a low-molecular-weight tripeptide comprised of three amino acids – cysteine, glutamic acid, and glycine. Its presence is pervasive, with significant concentrations found within virtually every cell of your body. At its core, GSH serves as a central hub for a variety of biochemical reactions, many of which are critical for maintaining cellular health.
🛡️ Shielding Against Oxidative Stress:
At the heart of Glutathione's prowess lies its ability to act as an antioxidant. To understand this, we must venture into the realms of free radicals highly reactive molecules that can wreak havoc on your cellular structures. GSH swoops in like a molecular guardian, neutralizing these renegade radicals and preventing cellular damage.
🔄 Recycling Antioxidants:
GSH doesn't stop at just neutralizing free radicals. It has a unique capacity to regenerate other antioxidants, such as vitamin C and vitamin E, which are also instrumental in combating oxidative stress. This recycling process amplifies the body's antioxidant defenses, making it a true linchpin of cellular protection.
💪 The Multifaceted Benefits of Glutathione:
1. Immune Resilience: By fortifying the immune system, Glutathione empowers your body to defend against pathogens and infections more effectively.
2. Detoxification Dynamo: As a vital component in phase II detoxification, GSH aids in the removal of harmful substances, thereby bolstering liver health and overall detox processes.
3. Anti-Aging Elixir: The anti-aging properties of Glutathione are tied to its ability to quell oxidative stress and cellular damage, potentially slowing down the aging process.
4. Skin Health: Some individuals explore Glutathione for its role in skin lightening and brightening, although its effects can vary among individuals.
📚 Diving into the Research:
1. "The Role of Glutathione in Cellular Response to Chemotherapeutic Agents"
- A scholarly article by Maria Serpina and John D. Hayes, featured in the Journal of Biological Chemistry.
2. “Glutathione as a Biomarker in Oxidative Stress: An Overview"
- An in-depth review by Farzaneh Rahmani and Hossein Aslani, published in the Journal of Medical Biochemistry.
3. "Mechanisms of Glutathione-Dependent Protection Against Oxidative Stress and Nitric Oxide-Induced Neurotoxicity in a Neuronal Cell Line"
While Glutathione supplements are gaining popularity, it's imperative to seek counsel from a healthcare professional before incorporating them into your regimen. Your individual health and physiology can influence the efficacy and safety of supplementation.
Stay curious, stay informed! 📖✨
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mintiestcrystal · 9 months
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i find it so unfair that i cant do all the science. like what do you MEAN I can't study bio and chem and biochem and atrophysics and physics and geology and climate science. what do you MEAN i have a limited lifespan and need to get out of school at some point to get a job. i want to collect the science fields like pokemon, this isn't fair
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womanofwords · 5 days
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STEM Kids Shenanigans (Chapter 39)
Chapter 39: Unwanted Appearances
Layla adjusted her hijab and went through her notes. The only thing going through her mind right now was what quotes to use in her English essay.
She certainly wasn't thinking about Stephan Marriot.
"Good morning, Ismail," Stephan snarled.
"Since when were we on a last-name basis?" Layla asked. "In fact, since when were we on a talking basis? Get away from me."
"No!" Stephan declared, causing passing students to look his way. "You ruined my life."
"You ruined your own life. Now leave me alone." Layla tried to leave, and Stephan blocked her.
"You haven't seen the last of me," he hissed, smirking at her before finally leaving.
I don't need to be a genius to know he's going to do something stupid, awful, or both, Layla thought, as students steered clear of him even now.
(PAUSE)
"So he's been acting weird towards you and said you hadn't seen the last of him?" Angelo asked, during their STEM club meeting.
"Pretty much," Layla said.
"I'll pour laxatives into his drink if you want me to," Yujin offered.
Dante choked on his water. "You have laxatives?"
"Yeah. Leave me near his drink and I'll put them in," Yujin said.
"But for that to work, you'll need a distraction. I'll deploy the flying bag trick," Angelo said, holding the backpack by the small upper handle and waving it for emphasis.
"I forgot you could do that," Layla mused.
"Yujin, you get the laxatives. I'll get the controls," Angelo said. The couple went to seek out Stephan Marriot while Dante got out a piece of paper, a pen, and tape.
"And what are you doing?" Layla asked.
"Making a much more rudimentary version of revenge," Dante said, writing the words 'KICK ME' on the piece of paper. Outside, they could hear screams of terror as Stephan was being chased around by a bright green flying backpack.
"THE BACKPACK'S ALIVE!" he screamed, as the backpack whirred towards him menacingly. "HELP! SOMEONE HELP ME!"
"Angelo got to him, didn't he?" Dante asked.
"Yep," Dante laughed.
(PAUSE)
Registration came, and the four members of the STEM club went in for registration with no issues. Melanie came in to a cold reception of angry students. And Stephan, who didn't even go here, arrived in a spectacularly messy fashion.
"This school is haunted!" he announced. His clothes were a mess, he had feathers in his hair, and when he turned around, there was a 'KICK ME' sign fixed to his back, swinging like a pendulum. "I saw a flying green winged monster in this school and it chased me!"
"What?" Mr Oluwatola blurted out, as students laughed at the ridiculousness of it all. "Is this why you look like you got dragged through a hedge backwards?"
"Yes," Stephan panted. "And it's because of the STEM club!"
"Why do people always blame us for things?" Yujin asked, staring at the water bottle she'd spiked.
"Honestly, it's ridiculous! First Melanie, and now you!" Dante complained.
"Can't we just . . . have a moment's peace?" Angelo whimpered.
"Stephan, the members of the STEM club have been through more than enough. Leave them alone," Mr Oluwatola ordered.
"They're haunting the school with their science and . . . stuff! You have to believe me!" Stephan wailed.
"No, we don't," Layla retorted, laughing along with everyone else. "We really don't."
Stephan growled and looked at Layla and the three other members of the STEM club with hatred before he flounced off. Layla grinned at him.
Checkmate, she thought to herself.
(PAUSE)
At the end of the day, a foul smell wafted through the hallways of Marbleton Secondary School. "Why does our school smell like sewage?" Dante groaned, as people held their noses. Other comments punctuated the air as students compared the stench in the air to that of a pigsty, while others settled for gagging and coughing.
"Someone please open a window before I faint," an unfortunate substitute teacher instructed, as students hastily complied.
"The laxatives I gave Stephan had a strong effect on him," Yujin whispered to Layla.
"This is all you?" Layla hissed back.
"Yep," Yujin smiled, holding her nose. "Nobody messes with our friend."
The smell appeared to pass next to their classroom as a boy hiding his face with shame held a plastic bag filled with clothes and tied tight. Clearly, the smell was coming from the bag of clothes, and the bag of clothes had not been tied tightly enough to keep the smell inside of it.
Yujin Moon was truly brutal.
To read the other parts of this fic, see Masterlist.
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somniphobicfox · 1 year
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Do science nerds actually talk using scientific terms like they show in movies and TV shows?
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undertalethingems · 6 months
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Unexpected Guests Chapter 10, Act Two: Page 6
First / Previous / Next
Out of sight doesn't mean out of mind.... Gaster won't let anything interfere with his goal.
Look for the next update on Nov. 16th!
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