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berrysweetboutique · 4 years
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Cherry Blossom:
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It’s a good thing you’re an adult! That could have been really traumatic.
Cherry Blossom: .... Excuse me I have to go bleach my eyes.
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hecalledmedarlin · 6 years
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Liked on YouTube: Trump Stoked A Culture War Over Masks That Put Everyone At Risk, Even The Secret Service https://www.youtube.com/watch?v=srg3-FLAjh8
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healthtimetaylor · 5 years
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Ginsenoside Rg3 has stereoselective anti-cancer effects in the AQP1 high-expressing cell line MDA-MB-231.
PMID:  Pharmaceuticals (Basel). 2019 Aug 1 ;12(3). Epub 2019 Aug 1. PMID: 31374984 Abstract Title:  Stereoselective Anti-Cancer Activities of Ginsenoside Rg3 on Triple Negative Breast Cancer Cell Models. Abstract:  Ginsenoside Rg3 (Rg3) has two epimers, 20(S)-ginsenoside Rg3 (SRg3) and 20(R)-ginsenoside Rg3 (RRg3), and while Rg3 itself has been reported to have anti-cancer properties, few studies have been reported on the anti-cancer effects of the different epimers. The aim was to investigate the stereoselective effects of the Rg3 epimers on triple negative breast cancer (TNBC) cell lines, tested using cell-based assays for proliferation, apoptosis, cell cycle arrest, migration and invasion. Molecular docking showed that Rg3 interacted with the aquaporin 1 (AQP1) water channel (binding score -9.4 kJ mol). Theoocyte expression system was used to study the effect of Rg3 epimers on the AQP1 water permeability. The AQP1 expression in TNBC cell lines was compared with quantitative-polymerase chain reaction (PCR). The results showed that only SRg3 inhibited the AQP1 water flux and inhibited the proliferation of MDA-MB-231 (100μM), due to cell cycle arrest at G0/G1. SRg3 inhibited the chemoattractant-induced migration of MDA-MB-231. The AQP1 expression in MDA-MB-231 was higher than in HCC1143 or DU4475 cell lines. These results suggest a role for AQP1 in the proliferation and chemoattractant-induced migration of this cell line. Compared to SRg3, RRg3 had more potency and efficacy, inhibiting the migration and invasion of MDA-MB-231. Rg3 has stereoselective anti-cancer effects in the AQP1 high-expressing cell line MDA-MB-231.
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berrysweetboutique · 4 years
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Mango: It’s fine, I’ll just sit back here and talk to... myself.
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berrysweetboutique · 4 years
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Mango and Peche came for a visit. And Mango immediately started lecturing the cat. 
Heh remember when another universe’s Merlot and Lacey were stuck inside Lacelot?
hahah because I sure don’t....  >.>
Lacelot: *looks into the camera like they’re on the office”
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berrysweetboutique · 4 years
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Rando Townie #9: Awww that’s nice.
These two cannot get a moment alone today.
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berrysweetboutique · 4 years
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Lace: So I heard you and Cherry are an item now? Eh? Eh?
Peche: Ehhhhh? Yes?
Cherry Blossom: *from the other room* OMB Mom! Stop!
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berrysweetboutique · 4 years
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What in my name is this monstrosity...?
You left me like this since Tiger King ™
Oh right... sorry about that. Let’s fix it.
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berrysweetboutique · 4 years
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Magnolia: I think it’s time we move out.
Butterfly Kisses: Why’s that?
*giggles and shower water running*
Magnolia: Take a guess.
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berrysweetboutique · 4 years
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Poor girl is still feeling cruddy after their lackluster karaoke.
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berrysweetboutique · 4 years
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Lace: Veggie Burger please.
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berrysweetboutique · 4 years
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Lace: This veggie burger isn’t very good... I’m sorry. I’m a bit of downer tonight.
Merlot: Let’s get out of here, darlin.
Lace: Kay.
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berrysweetboutique · 4 years
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Merlot: Good?
Lace: Nothing could be better.
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berrysweetboutique · 4 years
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Merlot: For you.
Lace: Pancakes! Aww you didn’t have to do that.
Merlot: It was nothing.
Lace: You’re so sweet.
Merlot: Who me? Nah.
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berrysweetboutique · 4 years
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Lace: My little ray of sunlight.
Merlot: Heh.
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