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#toxoplasmosis
great-and-small · 14 days
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I woke up feeling very anxious this morning and went for a walk to get my blood moving for the Monday crunch. Nearing home, I encountered someone a little shy, and lot curious. This cat went from "I'm extra big, you don't scare me" to "let me show you my belly" real quick. I'm always surprised that people have outdoor cats in this neighborhood; the local coyotes and raccoons (like those I caught skittering into a culvert in the botanical gardens a few minutes earlier) are happy enough to have a go at them. We get speeders all the time, and not every cat is quicker than every car. If they venture a couple blocks too far in the wrong direction, there are mountain lions eager to make a snack of them. I always hope that people will start caring that allowing cats outdoors is really bad for both biodiversity (all the critters the cats kill for play) and for the cats themselves. The average lifespan of outdoor cats is 2-5 years, while most indoor cats can be expected to make it to 14. Indoor cats can get plenty of enrichment, and you should be willing to spend time on enrichment if you have a pet.
Here on the west coast domestic cats may be having an impact even on animals they're likely never to meet: otters and some other marine mammals are seeing outbreaks of fatal infections of Toxoplasma gondii, a parasite most commonly spread by cats. So here's a reminder not to flush your cat litter down the toilet - our waste treatment plants don't actually have the capacity to deal with parasites found in cat litter (they can handle dog and human feces much better).
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bpod-bpod · 6 months
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Arresting Replication
Protein identified that is essential for the replication of the parasite Toxoplasma gondii – potential as a target to treat the disease it causes – toxoplasmosis – which can cause a range of symptoms; but maternal transmission poses particular risks to the foetus including abnormalities or abortion
Read the published research paper here
Image from work by Rebecca R. Pasquarelli and colleagues
Molecular Biology Institute, University of California, Los Angeles, CA, USA
Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
Published in PLOS Pathogens, October 2023
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mcgruffthecrimedog · 6 months
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Trying to pet every cat in the world. On that toxoplasmosis grindset
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disabled-banana · 2 months
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toxoplasmosis
Anyone who has a cat in their home has heard of toxoplasmosis. It’s the reason pregnant people and children are told to stay away from the kitty’s litter box. Toxoplasmosis is a zoonotic disease that affects warm-blooded animals, including humans. This disease is caused by the single-cell parasite Toxoplasma gondii. Wild and domestic felines are considered their definitive hosts, as the immature eggs of T. gondii, called unsporulated oocysts, are shed in the cat’s feces. Cats get infected when they eat mice, rats, birds, or other types of wildlife that are considered intermediate hosts for the parasite. Around 24–72 hours after excretion, the oocysts sporulate and become infectious.
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ambient-sanctuary · 3 months
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askpokeeosin · 1 year
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Boop you’re a cat!
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Cat feces is not the only way that Toxoplasma gondii, the protozoan parasite that causes the disease Toxoplasmosis, is spread. It is the vector that everyone remembers, though.
Also, shout out to long dead memes from when I was in high school.
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moththyme · 2 months
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📆 June 2023 📰 Latent toxoplasmosis impairs learning and memory 🗞 Nature
Tachyzoites are the rapidly-multiplying form of T. gondii, with capability to invade the excitable cells in skeletal muscles and nerves in which they differentiate to encysted bradyzoites. Bradyzoites are the semidormant, slowly-dividing form of the parasite, which persist inside the cells for the entire life of the host and form the chronic latent phase of toxoplasmosis.
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danbensen · 11 months
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Do what scares you! Follow the urging of your brain parasites beyond the firelight and into the unknown night! Find the mysteries of the universe and place your head between their fangs. The Admirable Self-Flinger approves of your recklessness.
from Fellow Tetrapod
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lunar-goodness · 1 year
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Went down a little bit of a parasitology rabbit hole this morning.
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bpod-bpod · 1 year
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Secrets of Secretion
Like an unwanted visitor that plonks themselves down on your sofa and starts emptying the contents of their bag everywhere, Toxoplasma gondii- the single-celled parasite that causes toxoplasmosis – invades cells and secretes many damaging proteins. To explore how these proteins help the parasite (yellow in the pictured sample of mouse immune cells, pink) cause harm, researchers silenced various genes and observed the impact. When the production of one of these secreted proteins, ROP1, was blocked, the host immune system was able to clear the infection that would’ve been lethal if left unchecked. That suggests that ROP1 helps the parasite evade the immune system, and, importantly, this finding appears to apply to both mouse and human infections. The team also identified a host protein that ROP1 interacts with, pointing the way for future studies to unpick the mechanisms of infection and investigate ways to counter it.
Written by Anthony Lewis
Image from work by Simon Butterworth and colleagues
Signalling In Apicomplexan Parasites Laboratory, The Francis Crick Institute, London, UK
Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
Published in PLOS Pathogens, December 2022
You can also follow BPoD on Instagram, Twitter and Facebook
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15kbells · 2 years
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Can anyone help me find that meme that’s an animated pig saying “I curse you with toxoplasma gondii” ???
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evaoddveig · 1 year
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Jaxon appreciation post
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CTVT 🤝 Toxoplasmosis
Parasites that I think are Really Neat™
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