Genuinely so fucked up that being sick will deprive you of the pleasure derived from sleeping AND eating. Those were like 80% of my dopamine sources! What the FUCK am I supposed to even do now
For a show about diagnostic medicine, House does shockingly little actual diagnosis.
"Start him on antibiotics." Have you seen a bacteria? No? That's because apparently nobody on your team knows how to grow a culture or run a gram stain.
"It's probably cancer, start him on radiation." Without finding the cancer?? Without knowing what it is so you can decide on a treatment plan??
Very funny that actual diagnosis is too boring for House, so he just throws treatments at people until it almost kills them and demonstrates what the problem isn't.
Evolving peak SARS-CoV-2 loads relative to symptom onset may influence home-test timing | CIDRAP
Median SARS-CoV-2 viral loads, as measured by polymerase chain reaction cycle threshold (Ct) and antigen concentrations, rose from symptom onset, peaking on the fourth or fifth day of symptoms. Estimated rapid antigen test sensitivity was 30.0% to 60.0% on the first day, 59.2% to 74.8% on the third, and 80.0% to 93.3% on the fourth.
Plain English:
Highest viral load is ~4-5 days into symptom onset, which means you're most likely to test positive about a week after an initial infection.
That also means that if you're IC/HR/etc. (or healthy & just don't want a disease that has a high chance of turning into long-term disability) and need to isolate from someone who's likely been exposed, the "quarantine" period should be at least 4-5 days, if not up to a week.
This has been the case for several years, not new, and corroborated by virologists and epidemiologists I've spoken to about their own protocol for infection avoidance.
It is frustrating to see even the people who are trying to advocate for patients with post viral syndromes act as though there’s no biomedical evidence, no potential avenues for verified diagnosis, just because most doctors aren’t aware of what’s established fact for these syndromes - and/or aren’t willing to look.
It’s been well established that a two-day exercise test consistently identifies ME/CFS patients, and that swollen lymph nodes and other physiological signs observable by an outsider worsen after overexertion. Differences in mitochondria, T cells, killer cells, and cellular oxygen metabolism have been found consistently in ME/CFS patients. There are multiple studies showing strong evidence of these.
There are literally drugs in trials AND EVEN A COMPLETED TRIAL to repair the mitochondrial dysfunction that is the hallmark of ME/CFS. Why am I still seeing people talk like nothing medical is known about it??
Tilt table tests, to identify types of dysautonomia such as POTS, are even covered by many insurances! A halter monitor is a standard line of diagnosis for some types of heart related dysautonomias because it’s well established that ultrasounds of the heart don’t catch all heart problems because you have to be looking at the right moment to catch it.
There’s so much that is KNOWN and UNDERSTOOD and PROVEN about various post viral syndromes that just... gets ignored.
I keep seeing and hearing about articles that talk as though post-covid disorders are completely untestable and there’s no possible proof except that patients feel bad.
Even when you’re trying to say “believe the patients”, ignoring the huge amounts of evidence that something physical is going on leaves open the interpretation that people with post viral illnesses just have anxiety, or depression, or conversion disorder, or just have “wrong beliefs” about their bodies.
It’s irresponsible to write articles about post viral disorders without mentioning the physical evidence!!
We KNOW what kinds of problems to expect from a post viral syndrome and we know a lot about where the evidence for some of the most prominent of them shows up. So why are studies trying to “disprove long covid” by doing random blood tests instead of just running fucking tilt table tests and other established tests for problems that routinely show up as post viral syndromes?
These illnesses don’t get enough research funding, and there IS a lot that isn’t known, but it’s infuriating to watch all the progress that does exist get totally ignored except for patient advocates and the like 5 decent doctors specializing in dysautonomia.
A lot of patients are being ignored and treated badly, not because there’s no possible evidence of what’s going on with their bodies, but because doctors (and others) are assuming there’s no value in referencing the literal decades of research that clearly indicates where to look.
It’s infuriating. You don’t have to GUESS why ME/CFS patients (and long covid patients with PEM) are exhausted all the time, or why long covid patients’ hearts race when they stand up. You don’t have to chalk it all up to depression or anxiety or Patients Are Wrong Disease!! YOU COULD LITERALLY JUST CHECK.
Buried: 527 words -- forced myself to finish the chapter.
Ghost on the Couch: 227 words -- I need to push myself to finish this too because I'm literally on the last chapter and I'm SO CLOSE.
Uploaded a new Tumblr exclusive fic.
I very suddenly have to move so I've been busy packing and also my cats just keep getting sick with this weird virus that just keeps coming back and ugh. But I really really do want to get back to writing regularly someday.
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