#yosuke ohnishi

[2001hz]

Yosuke Ohnishi, jca annual 4 (1982)

#my scan #yosuke ohnishi #jca annual #1982 #japan #illustrations

[a-state-of-bliss]

Photography by Yosuke Ohnishi

#fashion #yosuke ohnishi

[jca-archive]

Yosuke Onishi, 1978

#yosuke onishi #yosuke ohnishi #scans #70s #illustration #airbrush #eye

[theleoisallinthemind]

Yosuke Ohnishi, from JCA Annual 6 (1985)

#red #lips #Yosuke Ohnishi

[vulnerableunapologetic]

Yosuke Ohnishi

#Yosuke Ohnishi #80s #80s nostalgia

[anamon-book]

知ってるようで知らない性常識　大島清 ポケットブック ポケットブック社 カバーイラスト＝大西洋介 フォト・ディレクター＝山崎虎之介、モデル＝加山なつ子・立花あやか 本文イラスト＝大川清介

#知ってるようで知らない性常識 #kiyoshi oshima #大島清 #pocket book #ポケットブック #yosuke ohnishi #大西洋介 #anamon #古本屋あなもん #あなもん #book cover

[caviardujour]

#Yosuke Ohnishi

[aumonique]

Yosuke Ohnishi, 1983

#Yosuke Ohnishi #Art #Cherries

[teamtakeiemi]

Here's the official promotional poster for "Rurouni Kenshin Saishusho: The Final / The Beginning".

Tsuchiya Tao and Iseya Yusuke to also reprise their roles as Makimachi Misao and Shinomori Aoshi respectively.

ONE OK ROCK is said to have produced new songs as movie themes for "Rurouni Kenshin" again.

Roadshow in JAPAN: (Kindly wait for future announcements regarding international release dates.)

The Final - July 3 The Beginning - August 7

Himura Kenshin - Sato Takeru Kamiya Kaoru - Takei Emi Sagara Sanosuke - Munetaka Aoki Takani Megumi - Aoi Yu Myojin Yahiko - Ohnishi Riku Saito Hajime - Eguchi Yosuke Yukishiro Enishi - Arata Mackenyu Yukishiro Tomoe - Arimura Kasumi Makimachi Misao - Tsuchiya Tao Shinomori Aoshi - Iseya Yusuke Shishio Makoto - Fujiwara Tatsuya

Follow Rurouni Kenshin official accounts:

https://www.instagram.com/ruroken_movie/ https://twitter.com/ruroken_movie

Official website:

http://wwws.warnerbros.co.jp/rurouni-kenshin2020/

Sources:

https://twitter.com/ruroken_movie/status/1242571936883826688 https://twitter.com/ruroken_movie/status/1242572924512432128 https://twitter.com/ruroken_movie/status/1242572330720620544 https://twitter.com/ruroken_movie/status/1242573717235847168

#Takei Emi #Emi Takei #武井咲 #Sato Takeru #Takeru Satoh #佐藤健 #Rurouni Kenshin #Rurouni Kenshin Saishusho #るろうに剣心 #るろうに剣心 最終章

[jca-archive]

Yosuke Onishi, 1979

#yosuke onishi #scans #70s #airbrush #retro #yosuke ohnishi

[ainnah-chan]

19. RUROUNI KENSHIN

MOVIE RELEASED : 2012 (Origins)

2014 (Kyoto Inferno)

2021 (The Final)

Not yet released but announce this 2021 (The Beginning)

GENRE: Action

CAST: Satoh Takeru, Emi Takei, Yosuke Eguchi, Munetaka Aoki, Yu Aoi, Yusuke Isaya, Tao Tsuchiya, Mackenyu Arata, Riku Ohnishi

SYPNOSIS:

The Origins:

Former legendary assassin Kenshin Himura has now become a wandering samurai. Offerring aid & protecting those in need as atonement for his past deeds. During this time Kenshin Himura comes across and aides Kaoru Kamiya. Her father opened the Kamiya Kasshin-ryu, a kendo school located in Tokyo and Kaoru is now an instructor there. Kaoru then invites Kenshin to stay at her dojo. Their relationship develops further, but Kenshin is still haunted by his violent past ...

Kyoto Inferno:

Kenshin Himura goes up against pure evil Makoto Shishio who is attempting to overthrow the Meiji government. The fate of the country hangs in the balance as Kenshin Himura takes up the sword that he vowed to never draw again.

The Final:

Kenshin Himura is a legendary swordsman. After the Meiji Restoration, he has stopped killing with the sword. He tries to live a peaceful life with Kaoru Kamiya who runs a swordsmanship school in the village. Things change. Akabeko Restaurant, which is Kenshin Himura’s favorite place to eat, is destroyed. Kenshin Himura finds a note written “Junchu” there.

Based on popular manga series "Rurouni Kenshin: Junchuhen“ by Nobuhiro Watsuki (published in Weekly Shonen Jump from September 2, 1994 – November 4, 1999).

🗡 GREAT MOVIE !!!! 🤩

🗡 This Movie is Number 1 for the best Live Action Movie Ever !!!! 🤩

🗡 I love everything abouth this Movie !!

🗡 The Casts are all AMAZING !!!! 🤩

🗡 The Cinematography is SUPERB !!!! ♥️

🗡 Satoh Takeru is definitely the Best Japanese Actor of all time !! HIS ACTING SKILLS IS SUPERB !!!! 💯💯

🗡 The OSTs are SOOOOOO AMAZING !!!

One Ok Rock is THE BEST!!! I LOVE ALL OF THEIR SONGS !!!

THE BEST THE BEST THE BEST THE BEST

💯💯♥️♥️

Satoh Takeru the best Action Movie Star!!

♥️

SUPER LOVE THIS MOVIE !!

The animated series was my Childhood!! Soooooo happy they made this Live Action!!

HIGHLY RECOMMENDED !!!! 💯

#JdramaRecommendations #JmovieRecommendations #Jdrama #Jdorama #Jmovie #JapaneseDrama #JapaneseMovie

💜💜

#jdrama #jmovie

[retrocall]

Yosuke Ohnishi (1984)

#Retro #retrowave #retrowave collector #airbrush #original #scan #80s #1980 #80's #eighties #synthpop #vaporwave #vhs #neon #outrun

[liiimbo]

retrowavecollector: Yosuke Ohnishi (1984) http://ift.tt/2BnEDjw

#LIIIMBO

[mariebenz]

Subtype of Schizophrenia Can Be Identified by Enzyme in Hair

Dr. Yoshikawa MedicalResearch.com Interview with: Dr.  Takeo Yoshikawa MD PhD RIKEN Center for Brain Science Japan MedicalResearch.com: What is the background for this study? What are the main findings? Currently available drugs for schizophrenia are the dopamine D2 receptor blockers. These compounds were serendipitously discovered over half-century ago. But about 30% of schizophrenia are resistant to the dopamine D2 receptor blockers. In spite of these conditions, pharmaceutical companies have abandoned the development of new drugs. This is because we do not know the principle of drug design. Therefore, we need to understand the molecular underpinning of as-yet unknown schizophrenia pathophysiology. Schizophrenia is diagnosed by only patients’ symptoms, not by biological examination. To search for biological underpinning for schizophrenia using experimental animals, we thought that we should examine an endophenotype (biological trait) relevant to schizophrenia. Then we targeted prepulse (PPI) performance. Here, dampened PPI is considered as a biological marker of psychiatric disorders, typically of schizophrenia. Importantly, PPI can be measured using the same behavioral paradigm between experimental animals and human. C57BL/6 (B6) inbred mouse shows higher (better) prepulse inhibition (PPI) performance, while C3H/He (C3H) inbred mouse shows lowered (worse ) PPI. We premised that C3H mouse is “schizophrenia-prone” and B6 is not. To know the molecular basis for differential PPI levels between the two inbred mouse strains, we performed comprehensive protein expression level analysis (proteomics analysis) using the brains of B6 and C3H mice. The expression levels of Mpst, a hydrogen sulfide (H2S)-producing enzyme, is elevated in C3H mouse compared to B6 mouse. Biochemical analysis also supported the elevated H2S production in C3H mouse compared to B6. The examination of human samples including postmortem brains, iPS-derived neural stem cells (neurospheres) and hair follicle cells, gave evidence that H2S production system is indeed up-regulated in schizophrenia. MedicalResearch.com: What are the main findings?  The previous studies regarding H2S have mainly focused on the beneficial role of H2S.  This is because organisms including mouse and human synthesize H2S endogenously.  Our study shows that H2S, when it is excessively synthesized, brings a detrimental effect in the brain. A functional consequence elicited by excess hydrogen sulfide production, or  how brain function is damaged by excess H2S production, is that excess H2S hampers  energy metabolism in the brain. An origin or cause that induces the hyper H2S production state is, epigenetic changes of genome DNA (DNA methylation), not inherent genetic (genome) polymorphisms (variants). Epigenetic changes can be elicited by subtle brain insults including viral infection of pregnant  mother. This scenario conforms to the so-called “neurodevelopmental hypothesis of schizophrenia genesis”, and our work deciphered one of concrete entities (mechanisms) underlying this hypothesis. Our study provides a quite novel paradigm for schizophrenia pathophysiology, and is hoped  to provide a new principle for drug design.  MedicalResearch.com: What should readers take away from your report? Response: Development of inhibitors of H2S-producing enzymes could be a boon for schizophrenia patients, in particular those who are not satisfied with current drugs. MedicalResearch.com: What recommendations do you have for future research as a result of this work? Response: We call the hyper production state of H2S as “sulfide stress”.By further delineating the precise mechanisms for “sulfide stress”, for example identifying the proteins that are susceptible to “sulfide stress”, we could know additional druggable targets for schizophrenia. MedicalResearch.com: Is there anything else you would like to add? Response: Schizophrenia is thought to be etiologically heterogeneous. Examination of MPST (a H2S synthesizing enzyme) expression in hair follicle cells could identify the subgroup of schizophrenia suffering from “sulfide stress”, or stratify schizophrenia.We need just around 10 hairs, and such collection should be noninvasive. This could lead to precision medicine of schizophrenia. Thank you very much again for your interest in our work.  Citation: Masayuki Ide, Tetsuo Ohnishi, Manabu Toyoshima, Shabeesh Balan, Motoko Maekawa, Chie Shimamoto‐Mitsuyama, Yoshimi Iwayama, Hisako Ohba, Akiko Watanabe, Takashi Ishii, Norihiro Shibuya, Yuka Kimura, Yasuko Hisano, Yui Murata, Tomonori Hara, Momo Morikawa, Kenji Hashimoto, Yayoi Nozaki, Tomoko Toyota, Yuina Wada, Yosuke Tanaka, Tadafumi Kato, Akinori Nishi, Shigeyoshi Fujisawa, Hideyuki Okano, Masanari Itokawa, Nobutaka Hirokawa, Yasuto Kunii, Akiyoshi Kakita, Hirooki Yabe, Kazuya Iwamoto, Kohji Meno, Takuya Katagiri, Brian Dean, Kazuhiko Uchida, Hideo Kimura, Takeo Yoshikawa. Excess hydrogen sulfide and polysulfides production underlies a schizophrenia pathophysiology. EMBO Molecular Medicine, 2019; DOI: 10.15252/emmm.201910695   The information on MedicalResearch.com is provided for educational purposes only, and is in no way intended to diagnose, cure, or treat any medical or other condition. Always seek the advice of your physician or other qualified health and ask your doctor any questions you may have regarding a medical condition. In addition to all other limitations and disclaimers in this agreement, service provider and its third party providers disclaim any liability or loss in connection with the content provided on this website.   Read the full article

#medicalresearch #RIKEN_CBS #schizophrenia

[jaybe11]