bostorbio

[bostorbio]

Boster Bio Anti-CXCR3 Antibody Picoband™ catalog # PB9079. Tested in IHC, WB applications. This antibody (CXCR3 antibody) reacts with Human, Rat.

#CXCR3 antibody

[bostorbio]

Retinal pigment epithelium phagocytosis of rod outer segment fragments is controlled by MERTK (MERTK Antibody). Toll-like receptor-mediated innate immune responses are also suppressed by the activation of the transcription factor STAT1 by MERTK.

#MERTK Antibody

[bostorbio]

LaminA Antigen-Specific Antibodies – Boster Bio

The primary structural component of the nuclear lamina (lamin a antibody) on the inner surface of the nuclear envelope, nuclear lamins are intermediate filament proteins. The nucleus's inner nuclear membrane is lined by nuclear lamins, which are located on the cell's surface. There are two distinct forms of the Lamin A gene, Lamins A and Lamins C, which vary in their expression. There are distinct characteristics of embryonic stem cell development that are characterised by the appearance of lamin A/C (CDCD1, LMN1, EMD2). Lamins contribute to the structural integrity of the nucleus, but they also have a function in the nuclear matrix. Interactions with various chromatin proteins, including as histones and Lap2, allow lamins to contribute to the interphase chromatin structure, which in turn affects DNA replication, transcription, and RNA processing when the lamin organisation is disrupted.

The nuclear membrane's nucleoplasmic site is connected to the remainder of the cell via nuclear lamins, intermediate-type filaments. A-type lamins and B-type lamins (lamin a antibody) are two of the most common types of nuclear lamins. Three proteins that originate from the same gene by alternative splicing form the A-type lamins and two proteins that originate from two distinct genes form B-type lamins, which are referred to here as lamin B1 and lamin B2, respectively. Dilated cardiomyopathy, Emery-Dreifuss muscular dystrophy, and hereditary partial lipodystrophy of the Dunnigan type were all linked to A-type lamin mutations, which were previously unknown but now known to be dominant. When cells differentiate, they produce A-type lamins. Since A-type lamins preferentially cooperate with chromatin, it has been hypothesised that A-type lamins play a part in the regulation of gene expression.

#lamin a antibody

[bostorbio]

The JAK2 Antibody checks for blood levels of total endogenous JAK2 in the body. There was no evidence of cross-reactivity between members of the same family when tested in physiological conditions.

#JAK2 Antibody

[bostorbio]

IL33 ELISA – Boster Bio

To measure IL-33 (IL33 ELISA) levels in cell cultures, cell lysates, serum, and plasma, the Quantikine Human IL-33 Immunoassay uses a solid-phase ELISA that takes around four hours to complete. Antibodies raised against the purified factor are included in this package, as is an E. coli-produced human-specific IL-33 mutant. This immunoassay has been shown to accurately measure recombinant human IL-33. To develop linear curves that were identical to the standard curves obtained using the Quantikine kit, researchers used real human IL-33. IL-33's relative mass may be determined in a laboratory using this kit, according to the results of this study.

Human IL-33 (IL33 ELISA) was used to generate IL-33 samples that could be tested for linearity by serially diluting the assay samples with the appropriate Calibrator Diluent to produce samples with values within the assay's dynamic range. Diluting the samples was necessary before conducting the test.

Information about IL-33's history

Cells that have been physically injured or necrotic generate IL-33 (Interleukin-33). Th2-predisposed immune cell activation, in addition to development of regulatory T cells and M2 macrophages, all of which are advantageous. The ST2 and the IL-1 RAcP receptor complex is used by the body to connect with IL-33. As well as SCF/c-kit, SCF R/c-RacP, and IL-1 R6, IL-1 RAcP is connected with the other IL-1s. IL-33 bioactivity is regulated by structural and functional decoy receptors for IL-33, such as soluble ST2 and IL-1 RAcP.

#IL33 ELISA

[bostorbio]

Boster Bio Anti-MECP2 Antibody Picoband™ catalog # A00047. Tested in ELISA, IF, IHC-P, ICC, WB applications. This antibody (MECP2 antibody) reacts with Human, Mouse, Rat.

#MECP2 antibody

[bostorbio]

To respond to a 15 amino acid synthetic peptide from the amino terminus of human RIPK1 (RIPK1 Antibody), researchers created this peptide.

#RIPK1 Antibody

[bostorbio]

STAT6 Antibody  - Boster Bio

Polyclonal antibodies are produced when mice are immunised with a synthetic peptide that mimics Stat6 (STAT6 Antibody) residues around amino acid 620. Research in immunology use protein A and peptide affinity chromatography to separate antibodies from antigens.

An interleukin 4 and an interleukin 13-induced signalling cascade include the Janus family of tyrosine kinases (Jak) and the STAT signal transduction pathway, which includes the inflammatory cytokine receptor 6 (STAT6) (1). There has been some evidence that STAT6 (predicted molecular weight 94kDa) may be responsible for the cytokine's anti-apoptotic properties. To activate transcription, the STAT family members gather in the nucleus once they have been phosphorylated by the receptor associated kinases.

This activation occurs when STAT6 is phosphorylated (Tyr641) in response to cellular interaction with IL-4.This gene has been located in the lymphocytes of the periphery as well as in the colon and the intestinal tract and in the ovaries as well as in the prostate as well as in the thymus and spleen. An crucial function for STAT6 in Th2 and Th9 responses is played by this transcription factor (2). When STAT6 (STAT6 Antibody) is deficient in mice, IL-4-mediated activities such as Th2 helper T cell generation, production of cell surface markers, T-cell proliferation, immunoglobulin class flipping to IgE, and a partial loss of IL-4-mediated proliferation are all affected. Allergies to nuts and malignant hemangiopericytomas have a link with the overexpression of STAT6.

#STAT6 Antibody

[bostorbio]

It is known that interleukin 15 (IL15 Antibody) is structurally and functionally connected to interleukin 2 (IL-2). A lot of the body’s cells make it.

#IL15 Antibody

[bostorbio]

GPX4 Antibody – Boster Bio

When exposed to oxygen, the protein GPX4 (GPX4 Antibody) (Phospholipid hydroperoxide glutathione peroxidase, mitochondrial) protects cells against lipid peroxidation and cell death. This vitamin is essential for male fertility and sperm development. Approximately 20 kDa and 22 kDa are the molecular weights of the two isoforms that make up this protein. This particular monomer has an unusual tendency to form larger oligomers even though it is a monomer. The testicles are the primary site of involvement.

All across the body, Glutathione peroxidases (Gpxs) are proteins that catalyse glutathione's reduction of hydrogen peroxides and organic hydroperoxides. The basic structure and subcellular localization of each isoform of this protein are different. As the earliest member of the family of GPx enzymes, CGPx1 (classical cytosolic/mitochondrial glycolysis protein X1) relies on selenium. Genetic polymorphism, also known as gastrointestinal polymorphism (GI-GPx), is an intracellular enzyme that is located solely in the epithelium of the digestive system. In the majority of cases, it is created in the kidneys, which then release it into the bloodstream. Liver-produced extracellular plasma glutathione peroxidase (pGPx, or GPx3), is eliminated in the urine.Hydroxylipid hydroperoxide GPx4 (PH-GPx), a phospholipid hydroperoxide present in virtually all tissues, may reduce a broad variety of hydroperoxides, including those embedded in membranes, hydroperoxy lipids found in low density lipoprotein, and thymine. According to the most recent study, selenocysteine is present in the active region of all mammalian GPx (GPX4 Antibody) family members except for the Cys-containing GPx3 and the epididymis-specific secretory GPx (eGPx or GPx5) isoforms.

#GPX4 Antibody

[bostorbio]

Boster Bio Anti-Catalase Antibody Picoband™ catalog # PB9925. Tested in Flow Cytometry, IF, IHC-P, IHC-F, ICC, WB applications. This antibody (catalase antibody) reacts with Human, Mouse, Rat.

#catalase antibody

[bostorbio]

An enzyme proenzyme is released from the cells in the body that is known as MMP-3 (MMP-3 ELISA). The proenzyme has been shown to promote plasminogen activation, as previously reported.

#MMP-3 ELISA

[bostorbio]

Catalase Antibody — Boster Bio

It encodes the antioxidant enzyme catalase (Catalase Antibody), which is essential for the body's defence against oxidative stress. This gene. There are several enzymes in the peroxisomes of aerobic cells that break down heme, including catalase. Hydroxyl radicals, such as hydrogen peroxide, are deactivated by catalase, an enzyme in the body that converts them to water and oxygen. Oxidative stress has been linked to the development of several long-term and debilitating disorders including diabetes, Alzheimer's disease, rheumatoid arthritis, systemic lupus, and cancer. As of yet, only acatalasemia has been shown to be associated to this gene.

Biochemical and Physiological reactions

Reactive oxygen species are removed from the body with the help of catalase (Catalase Antibody). Deficiency of the catalase (CAT) gene causes the development of essential hypertension (EH). Hydrogen peroxide is broken down into water and molecular oxygen by it.

Descriptions and Benefits

You'll be able to examine your antibodies with complete confidence. As a customer, you may anticipate a complete refund or a replacement antibody if the antibody doesn't perform as intended in your application.

Phenomenological kind Sodium azide, 0.02 percent, and 50% glycerol in PBS (pH 7.4) with rabbit IgG. pH 7.4 (in the absence of Mg2+ and Ca2+).

#Catalase Antibody

[bostorbio]

For transcriptional regulation, this gene encodes a nuclear protein with the Runt DNA-binding domain, which is part of the RUNX (RUNX2 Antibody) family.

#RUNX2 Antibody

[bostorbio]

MUC2 Antibody – Boster Bio

Molecular weight-heavy glycoproteins, known as mucins, are an important part of the mucus layer that shields the stomach's epithelium from chemical and mechanical injury. Several human mucin genes have been revealed to code for different proteins in the mucin family. In addition to the normal colon, breast, prostate, and salivary glands, MUC2 antibody expression has been found in a range of cancerous tissues, including the digestive, colonic, breast, and prostate. This antibody labels MUC2 (MUC2 antibody) by producing a significant perinuclear staining in goblet cells in normal colon and colonic carcinomas. Also impacted by this substance are prostate adenocarcinoma, as well as normal and neoplastic breast tissue. As a preservative, BSA is used as a reducing agent in the buffer and sodium azide is used to concentrate the antibody, which is then dialyzed and filter sterilised before it is diluted in pH 7.5 buffer.

Functions

These proteins are the principal components of mucus that covers the surface of epithelial tissues and other epithelia, and they are heavily glycosylated.A total of nine epithelial mucin genes have been identified (Muc-1, 2, 3, 4, 5AC, 5B, 6, 7, and 8) that are expressed in the human body. In situ hybridization and immunohistochemistry investigations have shown that these mucins are expressed differently in epithelia depending on the cell type, and that their expression is controlled by the environment in various ways. Glycosylation changes, a rise in mucin polypeptide heterogeneity, and the appearance of simple mucin-type carbohydrates have all been linked to alterations in mucin polypeptide production in gastric cancer.

#MUC2 antibody

[bostorbio]

Boster Bio Anti-EPO Antibody Picoband™ catalog # A00484-1. Tested in ELISA, WB applications. This antibody (Epo antibody) reacts with Mouse, Rat.

#Epo antibody

[bostorbio]

A crucial role for KLF4 (KLF4 Antibody) in the development of epithelial cells and the maintenance of gastric homeostasis is played by this transcription factor.

#KLF4 Antibody