#Leukemia Therapeutics Market
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Global Leukemia Therapeutics Market, Forecast 2027
Leukemia Therapeutics Market
Leukemia is a type of blood cancer caused by gene mutation leading to abnormal development of WBCs in the bone marrow and causes leukemia. Leukemia is also caused due to risk factors such as genetic disorders such as Down syndrome, previous cancer treatments, exposure to chemicals, smoking, and family history of leukemia or other blood disorders. The major types of leukemia are Acute Myeloid Leukemia (AML), Chronic Myelogenous Leukemia (CML), and Chronic Lymphocytic Leukemia (CLL), Acute Lymphocytic Leukemia (ALL). The majority of the AML, CML & CLL cases could be observed in adult populations, and ALL could be seen in all age groups. Leukemia treatment is based on its type, age, and ability to cope-up with the treatments.
Market Size & Growth Rate:
The leukemia therapeutics market was valued at USD 13.5 billion in 2021 and is projected to reach USD 17.1 billion by 2027, with a CAGR of 7.2% over the forecast period 2022-2027. The growth could be attributed to the return of demand to pre-pandemic levels, increasing authorization of novel & innovative medicines, extensive research, disease prevalence, and immunotherapies.
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Market Dynamics:
On account of the growing number of people suffering from leukemia, the leukemia therapeutics treatment market has been driven by technological research & developments, the merging of healthcare organizations and new approvals in the field of blood cancer diagnostics across the globe.
The Leukemia & Lymphoma Society Therapy Acceleration Program (LLS TAP)-April 2021, announced five new investments in increasing the development of new and improved immunotherapies in Abintus Bio, Nexlmmune, Caribou Biosciences and Immune-Onc Therapeutics for the treatment of leukemia cancer.
Moreover, raising public awareness about the benefits of preventive healthcare is likely to move the demand for leukemia therapeutics treatment forward throughout the forecast period. Additionally, the Government initiatives and programs at increasing cancer awareness are expected to drive leukemia therapeutics treatment market expansion until 2027.
Market Drivers:
The growing research and technological development activities.
Increasing product approval and product launch by the market players are expected to propel the leukemia therapeutics market, and also technological developments are likely to create various new opportunities that will impact this leukemia therapeutics market growth in the forecast period. For instance,
In May 2022, Ivosidenib (Tibsovo, Servier Pharmaceuticals LLC) received FDA approval for combination with azacitidine in newly diagnosed AML with a susceptible IDH1 mutation in adults 75 years and older.
On June 2021, Jazz Pharmaceuticals received FDA approval for a new form of Rylaze (asparaginase erwinia chrysanthemi recombinant rywn) to be developed as part of a treatment for children and adults with ALL
In October 2021, Kite Pharma received FDA approval for use of the CAR T-cell therapy brexucabtagene autoleucel developed by Tecartus (the first CAR T-cell therapy approved) in adults with B-cell precursor ALL
In November 2018, Pfizer Inc. received U.S. FDA approval for Glasdegib (DAURISMO), the Hedgehog pathway inhibitor for the treatment of adults suffering from AML
Increasing incidence of leukemia to boost leukemia therapeutics market growth.
One of the foremost driving factors influencing the global market is the increasing prevalence of leukemia across the globe, according to the National Cancer Institute (NCI), approximately 1.5% of people were diagnosed with leukemia during their lifetime. Additionally, in the report-2022, the estimated number of living people with new leukemia cases will be 60,650, and the number of death cases will be 24,000 in the United States.
According to the American Cancer Society-2022, the CLL segment is anticipated 20,160 diagnosis cases including both children & adults in US leukemia therapeutic market, as CLL is the first line of treatment for it followed by AML and CML.
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Substantial progress has been made against cancer in recent decades. As of 2019, the rate has declined by 32%, mostly because of advances in early detection and treatment for some cancers including leukemia. It reflects largely driven by progress against leukemia cancer.
Challenges:
The high cost of treatment and stringent regulatory scenario restrain the market growth.
High cost of treatment and stringent regulatory scenario restraint the market growth over the forecast period. For instance, the NCI-2022 report estimates that cancer-related direct medical costs in the US were USD 183 billion in 2015 and are projected to increase to USD 246 billion by 2030, a 34% increase based only on population growth and aging.
The low diagnosis rate of leukemia & lack of proper healthcare facilities in developing countries
Adverse reactions of leukemia therapeutics
Competitive landscape:
Novartis International AG, Bristol Myers Squibb, Sanofi S.A, Pfizer Inc., Amgen Inc., Takeda Pharmaceutical, Celgene Corporation, GlaxoSmithKline plc, Abintus Bio, Nexlmmune, Exelixis Inc., MorphoSys AG, Otsuka Holdings Company Ltd, AbbVie, Ambit Biosciences corporation, Ariad Pharmaceuticals, Gennzme Corporation, Rpche, and Others.
Key Developments:
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Regional Analysis:
North America was the largest region in the leukemia therapeutics market in recent years and it is anticipated to capture the highest share of this market over the forecast period 2022-2027, with the U.S. accounting for the maximum contribution and it has well-developed structural healthcare systems. In addition, the high prevalence of leukemia and the rising geriatric population, based on the NCI-2022 report, leukemia represents 3.2% of all new cancer cases in the U.S., and the incidence rate increased in children and adolescents by about 1% per year and was stable in adults ages 20 and older. The presence significant of key players, some of the best research universities, and encouraging new product developments & launches for research lead to more significant assets in the pipeline. For instance,
In October 2022, The American Cancer Society (ACS) approved funding for 89 new Extramural Discovery Science (EDS) research grants totaling USD 54.3 million. It will fund investigators at 65 institutions across the United States from January 1, 2023.?
In November 2021, Pfizer Company acquired Trillium Therapeutics for approximately USD 2.22 billion, to enhance its oncology portfolio with the addition of next-generation immune therapies.
#Leukemia Therapeutics Market#leukemia care#global therapeutics market#innovative treatments#groundbreaking developments
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Leukemia therapeutics market is experiencing a surge in sales across the globe, and it has been considerably boosted by technological advancement.
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Global Leukemia Therapeutics Market Players
GSK, Pfizer, Novartis AG, Roche, Celgene, Biogen, Genzyme Corporation, Eisai C., and Bristol Myers Squibb Company are major Leukemia Therapeutics Market players in the leukaemia therapies industry (BMS). To achieve a competitive advantage, companies are implementing unique growth methods such as product launch, mergers and acquisitions, product pipeline, clinical trials, and partnership and agreements. Novartis, for example, has launched the tyrosine kinase receptor FLT-3 for leukaemia. Pfizer used a product expansion strategy to get a large market share, and its Bosulif medicine was approved by the FDA for the treatment of chronic myelogenous leukaemia (CML).
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Leukemia Therapeutics Market Outlook Sector, Forecast, Statistics and Outlook Till 2030
Leukemia therapeutics market is expected to grow significantly over the forecast period. It is anticipated that the market held value of USD 26,881.88 million in 2030 and is projected to grow at a CAGR of 7.50% over the forecast period.
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Acute Lymphocytic/Lymphoblastic Leukemia (ALL) Therapeutics Market size, Scope, Growth Opportunities, Trends by Manufacturers and Forecast to 2028
Industry Analysis
The acute lymphocytic/lymphoblastic leukemia (ALL) therapeutics market is expected to gain market growth in the forecast period of 2021 to 2028. Data Bridge Market Research analyses the market to grow at a CAGR of 5.25% in the above-mentioned forecast period. Rise in the prevalence of acute lymphocytic/lymphoblastic leukemia (ALL) drives the acute lymphocytic/lymphoblastic leukemia (ALL) therapeutics market.
Additionally, the credible Acute Lymphocytic/Lymphoblastic Leukemia (ALL) Therapeutics Market report helps the manufacturer in finding out the effectiveness of the existing channels of distribution, advertising programs, or media, selling methods and the best way of distributing the goods to the eventual consumers. Taking up such market research report is all the time beneficial for any company whether it is a small scale or large scale, for marketing of products or services. It makes effortless for healthcare industry to visualize what is already available in the market, what market anticipates, the competitive environment, and what should be done to surpass the competitor.
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Market Insights and Scope
Acute lymphocytic/lymphoblastic leukemia (ALL) therapeutics are the defined as the type of collection of drugs and therapeutic systems available in the market for its treatment. In this cancer, the blood and bone marrow are affected with cancerous cells which result in compromise of integrity of white blood cells. It is most common in pediatric patients as it occurs when the bone marrow cell consists of errors in its DNA, this generally occurs while the bone marrow is under development.
An international Acute Lymphocytic/Lymphoblastic Leukemia (ALL) Therapeutics Market research report examines competitive companies and manufacturers in the global market. Competitive analysis carried out in this market report puts forth the moves of the key players in the healthcare industry such as new product launches, expansions, agreements, joint ventures, partnerships, and recent acquisitions. This market report puts light on various aspects of marketing research that range from important industry trends, market size, market share estimates, sales volume, emerging trends, product consumption, customer preferences, historic data along with future forecast and key player analysis. It studies market by product type, applications and growth factors.
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Industry Segmentation
The acute lymphocytic/lymphoblastic leukemia (ALL) therapeutics market is segmented on the basis of age group, diagnosis, drug type, therapy, cell type and route of administration. The growth amongst these segments will help you analyse meagre growth segments in the industries, and provide the users with valuable market overview and market insights to help them in making strategic decisions for identification of core market applications.
On the basis of age group, the acute lymphocytic/lymphoblastic leukemia (ALL) therapeutics market is segmented into pediatrics and adults.
Based on diagnosis, the acute lymphocytic/lymphoblastic leukemia (ALL) therapeutics market is segmented into biopsy & bone marrow aspiration, complete blood count (CBC) & differential, presence of philadelphia chromosome, spinal tap & cerebrospinal fluid (CSF) analysis, immunophenotyping/phenotyping by flow cytometry and polymerase chain reaction (PCR).
Based on drug type, the acute lymphocytic/lymphoblastic leukemia (ALL) therapeutics market is segmented into existing drugs and pipeline drugs.
Based on therapy, the acute lymphocytic/lymphoblastic leukemia (ALL) therapeutics market is segmented into targeted drugs & immunotherapy, chemotherapy, radiation therapy, stem cell transplantation and pipeline.
Based on cell type, the acute lymphocytic/lymphoblastic leukemia (ALL) therapeutics market is segmented into philadelphia chromosome, precursor B-cell ALL and T-cell all.
The acute lymphocytic/lymphoblastic leukemia (ALL) therapeutics market is also segmented on the basis of role of administration into oral and parenteral.
Market Country Level Analysis
The countries covered in the acute lymphocytic/lymphoblastic leukemia (ALL) therapeutics market report is
U.S., Canada and Mexico in North America, Germany, France, U.K., Netherlands, Switzerland, Belgium, Russia, Italy, Spain, Turkey, Rest of Europe in Europe, China, Japan, India, South Korea, Singapore, Malaysia, Australia, Thailand, Indonesia, Philippines, Rest of Asia-Pacific (APAC) in the Asia-Pacific (APAC), Saudi Arabia, U.A.E, South Africa, Egypt, Israel, Rest of Middle East and Africa (MEA) as a part of Middle East and Africa (MEA), Brazil, Argentina and Rest of South America as part of South America.
An influential Acute Lymphocytic/Lymphoblastic Leukemia (ALL) Therapeutics Market research report displays an absolute outline of the market that considers various aspects such as product definition, customary vendor landscape, and market segmentation. Currently, businesses are relying on the diverse segments covered in the market research report to a great extent which gives them better insights to drive the business on the right track. The competitive analysis brings into light a clear insight about the market share analysis and actions of the key industry players. With this info, businesses can successfully make decisions about business strategies to accomplish maximum return on investment (ROI).
Industry Share Analysis
The major players covered in the acute lymphocytic/lymphoblastic leukemia (ALL) therapeutics market report is
Amgen Inc.; Bristol-Myers Squibb Company; Erytech Pharma; Novartis AG; Pfizer Inc.; Rare Disease Therapeutics, Inc.; Sanofi; Spectrum Pharmaceuticals, Inc.; Takeda Pharmaceutical Company Limited; Genmab A/S; Baxter; Gilead Sciences, Inc.; CELGENE CORPORATION; Eisai Co., Ltd.; SymBio Pharmaceuticals Limited; Kiadis Pharma; OBI Pharma; Astellas Pharma Inc. and Medexus Pharma, Inc. among other domestic and global players. Market share data is available for Global, North America, Europe, Asia-Pacific (APAC), Middle East and Africa (MEA) and South America separately.
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Chronic Lymphocytic Leukemia Market Is Projected to Grow at a Moderate Growth Rate During the Forecast Period | Loxo Oncology, Oncternal Therapeutics, MingSight Pharmaceuticals, Nurix Therapeutics
http://dlvr.it/T6WKyK
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Stemming Disease: The Evolving Hematopoietic Stem Cell Transplantation Market
The hematopoietic stem cell transplantation (HSCT) market has attracted major players owing to advantages such as long-term survival and disease remission for patients suffering from hematological malignancies and other disorders. HSCT involves transplantation of healthy stem cells either from the patient (autologous) or a donor (allogeneic) to replace damaged or destroyed bone marrow. The global HSCT market is estimated to be valued at US$ 2.88 Bn in 2024 and is expected to exhibit a CAGR of 11.% over the forecast period 2023 to 2030.
Key Takeaways
Key players operating in the HSCT market are Pluristem Therapeutics Inc., CellGenix GmbH, Regen Biopharma Inc., Lonza Group, Kiadis Pharma, Taiga Biotechnologies, Inc., Takeda Pharmaceutical Company Limited, Escape Therapeutics, Inc., Bluebird Bio, Inc., Talaris Therapeutics, Inc., Marker Therapeutics Inc., Stempeutics Research Pvt Ltd., CBR Systems Inc., Priothera Ltd., Eurobio Scientific Group, Otsuka America Pharmaceutical, Inc., Pfizer Inc., Sanofi, FUJIFILM Holdings Corporation. The major opportunities in the HSCT market include increasing prevalence of blood cancer and other hematological malignancies. Globally, the number of HSCT procedures is also growing owing to expanding healthcare infrastructure and increasing acceptance of stem cell therapies.
Market Drivers
The rising prevalence of blood cancer is a major growth driver for the HSCT market. According to statistics, around 10 million new cancer cases are reported worldwide each year, out of which around 1 million cases are of leukemia. HSCT is an effective treatment option for various blood cancers like leukemia, lymphoma and myeloma. Hence, increasing cancer burden worldwide is augmenting demand for HSCT.
PEST Analysis
Political: HSCT procedures require advanced healthcare infrastructure and stringent regulations regarding donor procurement and transplantation. Favorable healthcare reforms and investments in infrastructure strengthening cell and gene therapy capabilities.
Economic: High cost of HSCT procedures, expensive for most patients and insurance firms. However increasing availability of insurance coverage and funding programs improves accessibility and uptake. Newer therapies offering potential cost savings.
Social: Increasing awareness raising acceptance of HSCT for hematological conditions and cancer. Growth in medical tourism for developing countries lacking advanced healthcare. However some cultural and ethical issues regarding stem cell sourcing remains.
Technological: Significant advances in transplantation techniques, conditioning regimens, graft manipulation, and targeted therapies post-transplant improving outcomes. Developments in stem cell biology and genetic engineering enabling novel HSC sources and indications. Personalized medicine approaches tailoring transplants to individual patient needs.
The United States accounts for nearly one-third of the global HSCT market in terms of value concentrated in this region due to widespread insurance coverage, advanced healthcare infrastructure, high patient acceptance for transplantation, and presence of major industry players. North America is expected to remain the dominant regional market throughout the forecast period.
The Asia Pacific region excluding Japan presents the fastest growth opportunities for the HSCT market propelled by rapid economic development, healthcare reforms, growing medical tourism, and contract research and manufacturing activities by global industry players in countries like India and China. Increasing prevalence of hematological malignancies and genetic disorders due to aging populations also drive the demand for HSCT procedures in Asia Pacific.
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Evolving Trends in the Acute Myeloid Leukemia Market and a Vision Towards 2032.
Global Acute Myeloid Leukemia Market size will grow at 10.7% CAGR from 2024 to 2032, propelled by regulatory approvals for novel drugs and therapies for the disease treatment. Rapid advancements in treatment options and the ongoing R&D efforts are providing patients with access to more effective and targeted therapies for improving the overall outcomes. With strong focus on personalized medicine and innovative treatments, the acute myeloid leukemia (AML) industry will expand as new therapeutic options emerge while the existing treatments are optimized for enhanced efficacy. For instance, in December 2022, the FDA granted approval for OLU [89], an IDH1 inhibitor, for the treatment of relapsed or refractory (R/R) AML. This approval is based on a phase 1/2 trial involving patients with IDH1-mutant R/R AML who had not previously received IDH1 inhibitors.
The acute myeloid leukemia market is segmented into disease type, treatment type, route of administration, end-user, and region.
Based on disease type, the industry size from the myelomonocytic leukemia segment will achieve 11.6% CAGR up to 2032, driven by its prevalence as it accounts for a significant portion of AML cases. Myelomonocytic leukemia is characterized by the presence of both myeloid and monocytic cells, requiring targeted treatment approaches. With advancements in understanding the molecular mechanisms of this subtype, tailored therapies are being developed, further contributing to the segment growth.
Acute Myeloid Leukemia market size from the targeted therapy treatment type segment will foresee an 11.4% CAGR between 2024 and 2032. This is due to the efficacy and specificity of targeted therapies in treating AML, which often have fewer side effects compared to traditional chemotherapy. Drugs targeting specific mutations like FLT3, IDH1, and IDH2 are gaining prominence. The ongoing advancements in targeted therapy development and personalized medicine approaches for offering promising treatment options for patients will also drive the segment expansion.
Asia Pacific acute myeloid leukemia market will register a 12.3% CAGR from 2024 to 2032. The growth can be attributed to the increasing prevalence of AML, particularly in countries like China and Japan along with the rising aging population. Robust advancements in healthcare infrastructure are expanding the access to treatment options across the region. With the growing focus on personalized medicine and innovative therapies, Asia Pacific will further emerge as a key contributor in the acute myeloid leukemia industry.
#AcuteMyeloidLeukemia#AML#CancerTreatment#Oncology#MedicalResearch#Healthcare#MarketAnalysis#Hematology#PatientCare#MarketTrends
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#Leukemia Therapeutics Market#leukemia care#global therapeutics market#innovative treatments#groundbreaking developments
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Innovation in medication development, an increase in the number of biotechnology enterprises, and increased R&D spending are also projected to fuel the expansion of this industry.
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https://www.jeenee.net/read-blog/99778
Leukemia Therapeutics Market Outlook, Opportunities, Demand and Forecasts 2022- 2030
Leukemia therapeutics market is expected to grow significantly over the forecast period. It is anticipated that the market held value of USD 26,881.88 million in 2030 and is projected to grow at a CAGR of 7.50% over the forecast period.
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#‟acute lymphocytic/lymphoblastic leukemia (all) therapeutics‟#‟acute lymphocytic/lymphoblastic leukemia (all) therapeutics market‟#‟global acute lymphocytic/lymphoblastic leukemia (all) therapeutics market‟#‟acute lymphocytic/lymphoblastic leukemia (all) therapeutics market overview‟#‟acute lymphocytic/lymphoblastic leukemia (all) therapeutics research report‟
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