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caishozi-blog · 7 years

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Dose of TAC chemotherapy regimen for breast cancer chemotherapy

Treatment of cancer patients should take chemotherapy or radiotherapy, breast cancer treatment also need to take chemotherapy regimen for treatment, then what is the milk regimen? The usual breast cancer chemotherapy protocols are as follows:

The CMF scheme ---------28 days for 1 cycles

环磷酰胺 100mg / m2 after 第1 - 14天

Or cyclophosphamide, 600MG/M2, IV first, 8 days

With 40MG/M2 IV first, 8 days

Fluorouracil, 500MG/M2, IV, first, 8 days

AC regimen: 21 days repeated, a total of 6 courses

Adriamycin, 60MG/M2, IV first days

环磷酰胺 600mg / m2 iv 第1天

FAC or FEC scheme -------21 days for 1 cycles

氟尿嘧啶 500mg / m2 iv 第1天

Adriamycin, 0-50MG/M2, IV first days

70-80MG/M2 IV or epirubicin for first days

环磷酰胺 600mg / m2 iv 第1天

Docetaxel (Taxotere) 75MG/M2 IV for first days

Adriamycin, 50MG/M2, IV first days

ER (+) can be treated with endocrine therapy

after 三苯氧胺 10mg bid 3 - 5年

来曲唑 2.5mg designed for qd

Adjuvant chemotherapy for two stage breast cancer

Scenario 1: CMF regimen - 1~3 lymph node positive before menopause (4 weeks regimen)

Drug dose mg/ (m2.d) and pathway time (days) and procedures

环磷酰胺 100 after 1 ~ 14 q28d * 6

甲氨蝶呤 30 ~ 40 iv 1.8 q28d * 6

氟尿嘧啶 400 ~ 600 iv 1.8 q28d * 6x - d

Scenario two: CMF protocol - 1~3 lymph node positive (3 week regimen) 9q

Drug dose mg/ (m2.) and pathway time (days) and procedures

环磷酰胺 600 iv 1 q21d * 6

甲氨蝶呤 40 iv 1 q21d * 6

氟尿嘧啶 600 iv 1 q21d * 6n! it has $?

Scenario three: AC scheme - receptor negative, axillary lymph node positive

Drug dose mg/ (m2.) and pathway time (days) and procedures

Adriamycin 60iv 1 q21d*4

环磷酰胺 600 iv 1 q21d * 4

Scenario four: DOX----CMF scheme axillary lymph nodes: more than 3 positive adjuvant therapies

Drug dose mg/ (m2.) and pathway time (days) and procedures

Adriamycin 75iv 1 q21d*4

Immediately after 4 cycles

环磷酰胺 600 iv 1 q21d * 8

甲氨蝶呤 40 iv 1 q21d * 8

氟尿嘧啶 600 iv 1 q21d * 8

Scenario five: FAC and CAF protocols - more than 3 positive axillary lymph nodes, stronger than CMF

Drug dosage and route time (days) and procedures

氟尿嘧啶500毫克/（m2·d）四1,8 q28d * 6

阿霉素 50 mg / (m2) iv 1 q28d * 6

环磷酰胺 500 mg / (m2) iv 1 q28d * 6

Scheme six: ACT scheme: ER negative axillary lymph node is greater than 3.

Drug dose mg/ (m2.) and pathway time (days) and procedures

Adriamycin 60iv 1 q21d*4

环磷酰胺 600 iv 1 q21d * 4

Immediately after 4 cycles

泰素 175 iv 3h 1 q21d * 4

Scheme seven: ACT (dose density therapy) scheme

Drug dose mg/ (m2.) and pathway time (days) and procedures

Adriamycin 60iv 1 q14d*4

环磷酰胺 600 iv 1 q14d * 4

Immediately after 4 cycles

泰素 175 iv 3h 1 q14d * 4

Scenario eight: TAC programme

Drug dose mg/ (m2.) and pathway time (days) and procedures

泰素帝 75 iv 1 q21d * 6

Pretreatment: dexamethasone, 8mg, and Bid for 3 consecutive days (-1,1,2)

阿霉素 50 iv 1 q21d * 6

环磷酰胺 500 iv 1 q21d * 6

Neoadjuvant chemotherapy for resectable breast cancer

Scenario 1: FAC or CAF program

Drug dosage and route time (days) and procedures

氟尿嘧啶500 mg／（m2·d）四1,8 Q21D * 3

阿霉素50（48h输注）2 mg/m2 IV 1～Q21D * 3

Cyclophosphamide 500 mg/m2 IV 1 q21d*3

Scenario two: AC programme

Drug dose mg/ (M2) and pathway time (days) and procedures

Adriamycin 60iv 1 q21d*4

Cyclophosphamide 600 IV 1 q21d*4

Scheme three: ACD scheme

Drug dose (mg/m2) and route time (days) and procedures

Adriamycin 60 IV 1 q21d*4

Cyclophosphamide 600 IV 1 q21d*4

Immediately following

Taxotere 75 IV 1 q21d*4

One or two line and three line chemotherapy protocols for metastatic breast cancer

Scenario 1: Patients with previously untreated FAC or CAF protocols

Drug dosage and route time (days) and procedures

Fluorouracil 500 mg/ (m2.d) IV, 1,8, q21d*6 or more

Adriamycin 50 (48h infusion), mg/m2, IV, 1~2, q21d*6 or more

Cyclophosphamide 500, mg/m2, IV 1, q21d*6 or more

Scenario two: the NFL program is effective, toxic, poor in body and unable to use doxorubicin

Drug dosage and route time (days) and procedures

Mitoxantrone 12 mg/m2 IV 1 q21d*6 or above

Fluorouracil, 350mg/ (m2.d), IV, 1~3, q21d*6 or more

Cyclophosphamide 300mg/d before 5-Fu, with IV, 1~3, q21d*6 or more

Scenario three: PA programme

Drug dose (mg/m2) and route time (days) and procedures

175 IV 3H 1q21d*6 infusion of paclitaxel

(with dexamethasone, the treatment with cimetidine, Benadryl)

阿霉素 60 iv 1 q21d * 6

Scenario four: DA programme

Drug dose (mg/m2) and route time (days) and procedures

75 IV 1H docetaxel infusion (with dexamethasone and 1q21d*6 treatment)

阿霉素 50 iv 1 q21d * 6

Note: in combination chemotherapy, 35mg/ m2, once a week, for three weeks and a week off, is safer. For several consecutive cycles.

Scenario five: XD programme

Drug dosage and route time (days) and procedures

希罗达1275毫克/（m2·d）口服，1 ~ 14 Q21D

泰素帝 75 mg / m2 iv 1 q21d

Scenario six: GC programme

Drug dose (mg/m2) and route time (days) and procedures

健择 1000 iv 1.8 q28d * (4 ~ 6)

顺铂 75 iv 2 q28d * (4 ~ 6)

Scenario seven: Xeloda (Xeloda) single prescription

Drug dose (mg/m2.d) and route time (days) and procedures

希罗达 1275 to bid 1 ~ 14 q21d

Overexpression of HER-2 in the treatment of metastatic breast cancer

Scenario 1: AC*+Trastuzumab (Herceptin)

Drug dosage and route time (days) and procedures

adriamycin

表阿霉素 60 mg / m2 iv 1 q21d * 6

或 75 mg / m2 iv 1 q21d * 6

Cyclophosphamide 600 mg/m2 IV 1 q21d*6

Hessaitin (Trastuzumab)

4mg／kg（首次量）四周，直至疾病进展

2mg／kg（维持量）IV

* suitable for people who have never used anthracyclines before

Stevenson formula: body surface area (M2) = 0.061 * * 0.0128 height weight (kg) 0.1529

Scheme two: T *Trastuzumab (Herceptin)

Drug dosage and route time (days) and procedures

175 mg/m2 IV 3H paclitaxel infusion 1q21d*6

赫赛汀（曲妥珠单抗）4mg／kg（首次量）四周，直至疾病进展

2mg/kg (maintenance) IV

* suitable for people who have used anthracyclines in the past

Scenario three: TPC programme

Drug dosage and route time (days) and procedures

175 mg/m2 IV 3H paclitaxel infusion 1q21d*6

Carboplatin AUC6iv1q21d*6

Hessaitin (Trastuzumab)

4mg／kg（首次量）四周，直至疾病进展

2mg/kg (maintenance) IV

Endocrine therapy for breast cancer

A scheme of tamoxifen

Drug dosage and route time (days) and procedures

after 三苯氧胺 10mg bid

Or 20mg PO Qd orally daily for 5 consecutive years

Scenario two: MA or MPA monotherapy

Drug dosage and route time (days) and procedures

甲地孕酮 160mg while

Or 500mg PO orally daily until progression or intolerance to other side effects

Medroxyprogesterone was taken orally daily until progression or intolerance to other side effects

Scheme three: EXE monotherapy as second-line treatment after failure of tamoxifen endocrine

Drug dosage and route time (days) and procedures

Elong (Exemestane) 25mg PO new oral daily until disease progression.

方案四: anastrozole 方案三苯氧胺治疗失败的绝经期后的晚期乳腺癌病人生存期明显超过甲地孕酮

Drug dosage and route time (days) and procedures

Arimidex (Anastrozole) 1mg PO orally daily, until the disease progressed

Scenario five: Letrozole (Femara) monotherapy

Drug dosage and route time (days) and procedures

Letrozole (Letrozole), 2.5mg, and PO were administered orally daily until disease progression

方案六: goserelin depot (zoladex) 单药方案

Drug dosage and route time (days) and procedures

诺雷德库 (goserelin depot) 3.6mg sc 每月1次

Women's health network (Editor)

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