#Skin Graft Market Share
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Skin Graft Market Research: Understanding Size, Trends, and Outlook
Market Overview –
In 2022, the skin graft market was estimated to be worth USD 4 billion. The market for skin grafts is expected to expand at a compound annual growth rate (CAGR) of 7.01% between 2023 and 2032, from USD 4.28 billion in 2023 to USD 7.36 billion by 2032.
The skin graft market is witnessing steady growth driven by the increasing prevalence of skin-related conditions and trauma cases requiring surgical intervention. Skin transplant procedures, including autografts and allografts, offer effective solutions for wound healing and cosmetic reconstruction. With advancements in transplantation techniques and tissue engineering, the market continues to evolve to meet the growing demand for innovative skin graft solutions.
The skin graft market pertains to the healthcare sector focusing on procedures and products related to skin grafting. Skin grafting involves transplanting skin from one area of the body to another to repair damaged skin due to burns, injuries, surgeries, or skin diseases. This market encompasses various types of skin grafts, including autografts (from the patient's own body), allografts (from a donor), and xenografts (from another species), as well as synthetic skin substitutes.
The primary driver of the skin graft market is the increasing incidence of burns, trauma, and skin-related disorders worldwide. Burn injuries alone affect millions of people each year, creating a significant demand for skin grafts to promote wound healing and prevent complications such as infections and scarring. Additionally, advancements in surgical techniques, tissue engineering, and regenerative medicine have expanded the scope and effectiveness of skin grafting procedures.
Moreover, the growing awareness about the importance of aesthetic and reconstructive surgeries, along with the rising demand for cosmetic procedures, has further fueled the demand for skin grafts. Patients undergoing procedures such as Mohs surgery for skin cancer removal or cosmetic surgeries for scar revision often require skin grafts to achieve optimal outcomes.
The COVID-19 pandemic has impacted the skin graft market, with disruptions in elective surgeries, reduced hospital admissions, and changes in patient priorities. However, the pandemic has also highlighted the importance of wound care and infection prevention, underscoring the essential role of skin grafts in wound management and reconstruction.
Despite challenges such as availability of donor tissue, cost constraints, and variations in surgical outcomes, the skin graft market is expected to grow as innovations continue to improve graft survival rates, reduce complications, and enhance patient satisfaction. With ongoing research and development in tissue engineering, biomaterials, and regenerative medicine, the skin graft market holds promise for addressing the diverse needs of patients with skin injuries and disorders.
Segmentation –
The global skin graft market is segmented on the basis of graft type, graft thickness and applications. Based on graft type, the market has been segmented as autologous, isogeneic, allogeneic, xenogeneic and prosthetic. Based on the graft thickness, the market has been segmented as split-thickness, full-thickness and composite graft. Based on the applications, the market has been segmented as extensive wound, burns, extensive skin loss due to infection, skin cancers and others. Based on the equipment, the market has been segmented as dermatome (knives dermatomes, drum dermatomes, electric dermatomes, air dermatomes), general surgical instruments, consumables and others. Based on the end users, the market has been segmented as hospitals and clinics, academic and research and others.
Regional Analysis –
Regional analysis of the skin graft market reveals varying trends influenced by factors such as healthcare infrastructure, prevalence of burns and traumatic injuries, and availability of advanced medical technologies. In developed regions like North America and Europe, where there is a higher incidence of severe burns and extensive healthcare facilities, the skin graft market is well-established with a wide range of products and procedures available. Conversely, in developing regions with limited access to specialized burn care and reconstructive surgery, such as parts of Asia-Pacific and Africa, the market for skin grafts is still evolving. Moreover, cultural attitudes towards cosmetic and reconstructive surgery impact the demand for skin graft procedures across different regions. As awareness of the benefits of skin grafts for wound healing and aesthetic enhancement increases globally, there is a growing opportunity for market expansion through education, training, and technology transfer initiatives to address regional disparities in access to advanced skin graft solutions.
Key Players –
Skin graft companies include Organogenesis, Specimen Medical, Stratatech Corp, Tissue Regenix Group Plc, Avita Medical, Convatec Inc, Medtronic, Coloplast, Braun Melsungen, Stratatech Corporation, and Zimmer Biomet.
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#Skin Graft Market#Skin Graft Market Size#Skin Graft Market Share#Skin Graft Market trends#Skin Graft Market growth
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#skin graft market#skin graft market scope#skin graft market size#skin graft market share#skin graft market trend#skin graft market analysis
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Immunotherapy Drugs Market to Witness Huge Growth by 2030
Immunotherapy Drugs Market research report deals with many parameters in depth to satisfy the requirements of business or clients. Moreover, it also displays all the information including market definition, classifications, key developments, applications, and engagements along with the detailed actions of key players with respect to product launches, joint ventures, developments, mergers and acquisitions and effects of the same in terms of sales, import, export, revenue and CAGR values. A team of experienced and consummate market research professionals persistently track key industries to spot key developments, unmet needs and possible growth opportunities.
Immunotherapy Drugs Market, By Drug Type (Monoclonal Antibodies, Immunomodulators), By Indication (Infectious Diseases, Cancer) and by Region (North America, Europe, Asia-Pacific, Middle East and Africa and South America). The global Immunotherapy Drugs Market size is projected to reach a CAGR of 11.7% from 2023-2030.
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Immunotherapy drugs are used to enhance or suppress the immune system of the body. They are mostly used in the treatment of cancer and act by stimulating the immune system of the body and generating an immune response aiding the production of antibodies. Antibodies produced against antigens kill the cancerous or tumour cells.
The global immunotherapy market is driven by the increasing adoption of targeted therapies, the increase in the life span of patients, and the high prevalence of lifestyle diseases. Furthermore, rapid approval of drugs and reduction in the recurrence of diseases propel market growth. Additionally, immunotherapy as an alternative to chemotherapy and the use of immunotherapy as the first line of drug for the treatment of cancer provide growth opportunities for the market players shortly.
Immunotherapy Drugs Market Competitive Landscape:
Amgen, Inc.
Novartis AG
AbbVie, Inc.
Pfizer, Inc.
F. Hoffmann-La Roche Ltd.
Johnson & Johnson Services, Inc.
AstraZeneca
GSK
Sanofi
Bayer AG
Immunotherapy Drugs Market Recent Developments:
August 29, 2022 - AbbVie Showcases New Analyses and Real-World Data Across Multiple Immune-Mediated Skin Diseases at the European Academy of Dermatology and Venereology (EADV).
August 24, 2022 - AbbVie announced that the U.S. Food and Drug Administration (FDA) approved the use of IMBRUVICA® (ibrutinib) for the treatment of paediatric patients one year and older with chronic graft versus host disease (cGVHD) after the failure of one or more lines of systemic therapy.
Immunotherapy Drugs Market Key Findings:
Immunotherapy drugs are used to enhance or suppress the immune system of the body. They are mostly used in the treatment of cancer and act by stimulating the immune system of the body and generating an immune response aiding the production of antibodies. Antibodies produced against antigens kill the cancerous or tumour cells.
The indication segment is further fragmented into Cancer, Autoimmune Diseases, Infectious Diseases, and Others. The cancer segment accounted for the largest revenue share owing to the increased prevalence of cancer, coupled with a rise in the launch of cancer immunotherapies.
The drug type segment is further fragmented into monoclonal antibodies, immunomodulators, and vaccines. The monoclonal antibodies segment accounted for the largest share owing to increased R&D in therapeutic monoclonal antibodies coupled with supportive government initiatives.
The market is also divided into various regions such as North America, Europe, Asia-Pacific, South America, and Middle East and Africa. North America dominated the global industry and accounted for the largest share of the overall revenue. The launch and regulatory approval of new immunotherapy drugs and favourable reimbursement policies are projected to aid in the region’s growth.
Immunotherapy Drugs Market Regional Analysis:
North America to Dominate the Market
North America dominated the global industry and accounted for the largest share of the overall revenue.
The launch and regulatory approval of new immunotherapy drugs and favourable reimbursement policies are projected to aid in the region’s growth.
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Scope of the Immunotherapy Drugs Market Report:
Immunotherapy Drugs Market is segmented into various segments such as drug type, indication, and region:
On the basis of drug type
Monoclonal Antibodies
Immunomodulators
Vaccines
On the basis of the indication
Cancer
Autoimmune Diseases
Infectious Diseases
Others
On the basis of region
Asia Pacific
North America
Europe
South America
Middle East & Africa
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A New Era of Treatment: Epidermolysis Bullosa Market Insights
Epidermolysis bullosa is characterized by fragile skin and mucous membranes that blister and erode easily. The skin condition is caused by any one of a group of inherited disorders that cause the skin and sometimes mucous membranes to become very fragile, blister easily from minimal friction or trauma, and not heal properly. Epidermolysis bullosa can vary in severity from very mild to severe forms that are debilitating or life-threatening.
The global epidermolysis bullosa market is estimated to be valued at US$ 3,429.30 Mn in 2024 and is expected to exhibit a CAGR of 11% over the forecast period 2023 to 2030. Key Takeaways:
Key Players: Key players operating in the epidermolysis bullosa market are Amryt Pharma, Abeona Therapeutics, Castle Creek Pharmaceuticals, RegeneRx, Krystal Biotech, RHEACELL GmbH, Holostem Terapie Avanzate, StemRim/Shionogi, and Phoenix Tissue Repair. Amryt Pharma and Abeona Therapeutics hold a major share of the market currently.
Key Opportunities: Growing research initiatives for orphan drugs and therapies for rare diseases is creating new opportunities for market players. Increasing collaborations between researchers and biopharmaceutical companies will help develop new treatment options to address unmet needs.
Global Expansion: Major players are focusing on geographical expansion plans to strengthen their presence across key regions worldwide. Strategic acquisitions and partnerships are helping companies penetrate developing markets and boost production capabilities.
Market Drivers:
Growing prevalence of genetic disorders worldwide due to changing lifestyles is a major market growth driver. According to sources, around 500,000 people globally are affected by epidermolysis bullosa. Rising cases of skin blistering diseases will contribute to market revenue.
Growing R&D initiatives for developing novel treatments including gene and cell therapies hold significant potential to drive the market during the forecast period. Several clinical trials for stem cell and gene therapies are currently underway.
Market Restraints:
High treatment costs associated with existing therapies like wound dressings, skin grafting, and nutritional supplements limit broader market adoption. Lack of approved treatment options especially for severe forms of EB poses a major challenge.
Difficulties in clinical trial execution and high risks involved further delay market commercialization. Complexities in developing targeted treatments also act as a roadblock for market players.
Segment Analysis
The dystrophic epidermolysis bullosa segment has the largest market share as it is the most common and severe form of epidermolysis bullosa. The dystrophic epidermolysis bullosa market will continue to dominate owing to the current lack of treatment options and high unmet need for effective therapies. The junctional epidermolysis bullosa segment will have significant growth during the forecast period due to the increasing research activities and clinical trials for developing novel therapies for the treatment of junctional epidermolysis bullosa.
Global Analysis
North America holds the largest market share in the epidermolysis bullosa market due to the rising research and development activities by key players, increasing prevalence of epidermolysis bullosa, and advanced healthcare infrastructure in the region. The Asia Pacific is expected to grow significantly during the forecast period owing to the growing patient population, increasing awareness regarding the disease, developing healthcare infrastructure, and rising healthcare expenditures in countries such as India and China.
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LIKE A HOOK INTO AN EYE. (first draft; scrapped)
first draft of the prologue and the first scene of the first chapter for LIKE A HOOK INTO AN EYE. I'm thinking of scrapping these because the fic isn't really working for me; hence why I'm posting them here, and not on AO3.
one day I'll return to this story and figure out how to write it better. I will most likely still use the same premise (and will probably keep the title and summary), but the story itself probably won't be written the way it was here, for reasons I'll explain in another post.
anyway, here's my initial attempt at gothic horror, actor au vnlmi. cw for: character death, witch curses, ghost haunting (?), grafting someone else's body part into yours
LIKE A HOOK INTO AN EYE.
people think that grief
slowly gets smaller
with
time.
in reality, grief stays
the same size—
To honor Aether’s dreams, Lumine endeavors to bring to the stage the last unpublished play he wrote before his death. The only copy of the manuscript lies in the hands of a musician who wants to free Lumine from her haunting.
But how can she let him, when this haunting is all she has left?
PROLOGUE: DEATH (first draft)
Lumine didn’t kill him, but she might as well have.
Logically, it’s nobody’s fault. She’s cognizant of the blamelessness that comes with accidents. “Shit happens,” as Aether would say, with a cheeky smile and a shrug and that annoyingly endearing go-getter attitude that would have him “conveniently” forget any trauma or obstacle standing in the way between him and his unyielding, awful, all-consuming dreams.
Aether was brave and stupid like that. It killed him to pursue his dreams, but he’d die if he didn’t take those steps forward. Aether had an envious appetite for life. And he was, always, a hungry man.
Sometimes, Albedo doesn’t understand why Aether acted the way he did, not the way Lumine did. Aether had a way with words, a way of saying the most incomprehensible things that made you understand.
“I dream the way you love,” he once said, an off-hand comment from when they bought apples from the Sunday Market near Dornman Port. It didn’t even occur to him how easily he distilled both of their identities into six words. “Some say it’s maddening, but I like that about us. My dreams are your dreams. Your love is my love. We fit together the way only twins like us can.”
Aether often linked his left pinky with hers, warm flesh against synthetic skin. And for a second, they return to being one entity.
When they were still in their mother’s womb, their little fingers were fused together, bridging their two bodies. The doctor had to surgically remove it from one of them during birth. Like a wishbone, one split into two. Aether retained all of his appendages, while Lumine lived with a prosthesis fortified with condensed resin. It was state-of-the-art, made with expensive Khemia technology.
Aether often linked their fingers together to declare, like a promise, “We’ll always share everything, Lumine. What’s mine is yours. My wishes are your wishes.”
Aether and Lumine were born as extensions of one another. She is — was? — the moon to his sun. Aether understood everything about Lumine, and Lumine understood everything about Aether.
Aether, who is now six feet deep in the ground. He doesn’t even have all his bones with him.
Their former guardian, M, once told them that they inherited a witch’s curse from when their birth mother angered a sullen witch. She was cursed to gaze into the abyss, and that one of her children will inherit the same gaze. And when they do, they will pull the other with them, until all three of them have fallen.
The Gaze is a pull towards the abyss — towards death. M said that you cannot break a curse that you are born with. It is written into your being. You would have to rewrite the way you see — the way your soul is wired to perceive. But by then you wouldn’t be the same person anymore, and what would you even sacrifice to get to that point? The cost is never worth it. You would be trading one curse for another.
And so, you can only resist. Many people, according to M, have resisted such curses and lived long lives. M said the best way to resist is to gaze outward. There is a horizon beyond the abyss; there is something worth yearning for.
“I won’t kill you,” Aether had promised. “And you won’t kill me. We’ll live and we’ll grow old and when we die, we’ll be happy. We’ll find something that can save us from this curse. Gaze outward, Lumine.”
She did. On that day, they held hands and watched the sunset together, eyes fixed beyond.
Lumine didn’t kill Aether. Aether was the one who wanted to hike in Dragonspine, just the two of them, because he was struggling with writer’s block and he needed a change of scenery.
Lumine didn’t cause the blizzard in Dragonspine, didn’t cause Aether to slide horrifically across the cliffside during the terribly planned hiking trip. Aether knew this. He would tell her not to blame herself. She tried to hold his hand. She reached out when he fell.
Lumine didn’t kill Aether, didn’t intend to and didn’t want to. But she also couldn’t catch him in time.
It took the knights three days to find the body. Albedo, usually so well-composed and self-possessed, broke down when he saw the still corpse. Lumine was inconsolable.
And just like that, Aether has gone to the abyss. Not by a witch’s curse, but by bad weather and an unlucky hiking trip.
For the first time, Lumine is truly alone in the world.
—
Aether does not return to earth whole. A small, sterilized jar of bones and flesh sits cold at the back of a freezer, wrapped in moist gauze and damp with saline solution. Lumine hesitates everyday at breakfast and pushes the thought at the back of her mind.
Later. She’ll deal with it later.
After his death is announced to the public, Lumine encounters a man with brilliant teal eyes who gives her a little black notebook that once belonged to Aether.
“He left it in my studio,” he says. “I think he’d want you to have it.”
Lumine flips through the pages. It’s a poetry book.
“He left a lot of things in my studio, you know, CDs, notebooks, some of his drafts are even on my computer. But—” the man sighs, slipping a card into one of the pages,“—this is the only one I have with me today. When you want the rest of them back, come find me. I think I still have a draft of his last manuscript. I’ll keep them safe until you’re ready to get them.”
Lumine hides the notebook in her pocket. She thinks about reading through it, but whenever she looks at Aether, lying peacefully in the casket, a terrible thought tugs at her more urgently than the rest.
She would die with him. A part of her would be buried with him.
She couldn’t let him return to the earth whole. Aether can’t leave her alone.
Aether’s little finger sits in cold ice at home while they lower his body to the ground. This flesh were theirs. For everything that separated Lumine from Aether and vice versa, these bones belonged to them both.
The next day, Dainsleif informs her that she inherited all of Aether’s fortune, his responsibilities in the Abyss Foundation, and, of course, his plants. Lumine is two times richer than she was yesterday, and only half whole.
The little black notebook sits by Lumine’s windowsill, conveniently forgotten.
—
Lumine doesn’t open the notebook again until she’s forced to confront it.
The inheritance overwhelms her. The moneys sits untouched, the Abyss Foundation is ran by Dainsleif these days, and the plants are withering.
The knights ask Lumine to take some time off indefinitely, because a paramedic who can’t be present in the field is a liability. They don’t say that this is the real reason, of course. Neither do they mention the new responsibilities and wealth they assume (correctly) that she acquired, how that should be taking up her time instead, and anyway — dead sibling aside — she is much better off now, materially, than she was before. She doesn’t need to slave herself off of the meager salary of a first responder.
They don’t say any of that. Instead, they say that they’re concerned for her mental health, that it’s okay for her to grieve, that Noelle can handle things while she’s away.
Both things can be true at the same time. But one reason being true doesn’t negate the other.
They don’t force Albedo to do the same thing, because Albedo is responsible enough to actually use his time off when he needs it. He hasn’t worn the uniform in four months. There are rumors that he’ll quit the knights soon. Lumine wants to do the same.
She’s dead on her feet, unmoored and without purpose. How is she supposed to live without Aether? She’s scared to know, until one day she’s scared she’ll never know. Suddenly, the sight of the little black notebook no longer haunts her, but gives her hope.
Bolting from her bed in the middle of the night, Lumine grabs the notebook in a feverish daze. She wipes the dust off. A page falls off on her bed, just a small scrap of writing. It reads,
I borrow moonlight
for this journey of a
million miles
Lumine throws the notebook away, as if it burned her. A sharp paper cut slices through her skin, a centimeter off where the palm meets her synthetic finger. The pain registers only second to the loud beating of her own chest.
“No, don’t do this to me, Aether,” she whispers. Her prosthetic finger suddenly feels foreign to her, too cold and artificial.
Her hair has gotten long after months of neglecting to have it cut. From her reflection by the window, she could almost pretend it’s Aether staring back at her wild eyes. He tilts his head at her, as if to say, Go on. Read.
She swallows thickly and opens the notebook again. Another page reads,
While I walk on
the moon keeps pace beside me;
friend in the water
Now that my storehouse
has burned down, nothing
conceals the moon
Aether smiles patiently from the window as Lumine cries herself hoarse for the rest of the night.
—
Lumine opens the notebook again one week later, after replacing the saline solution in the jar that housed Aether’s (her?) severed finger. She still hasn’t decided on what to do with it yet.
Aether’s notebook of poetry functioned as a diary. It’s difficult to be vulnerable with your own words, but Aether found a way to channel his own helpless thoughts through other people. He always did that — live, through and for others.
This is what made him an excellent scriptwriter. He admired, and sometimes encouraged, the desire to live someone else’s life. To escape into someone else’s story and make it your own. He got that from M, Lumine is sure. M wrote children’s books, and Aether lived many lives through her stories.
Lumine, at least, isn’t alone in her grief. Aether was the darling of Mondstadt’s entertainment industry. When news of his death broke out, a local channel aired reruns of his movies. Finchster trended a hashtag for him.
Albedo stayed for dinner that day and marathoned the movies with Lumine. Aether loved to write happy, feel-good stories. Stories about love, friendship, family. Some of them are punctuated with intense drama or high-stakes adventure, and some of them are your run-of-the-mill romance and slice-of-life. But all of them, always, end on a hopeful note, if not a happy ending.
Aether smiled on tv. They re-ran his interviews in-between the movies. “I do want to challenge myself creatively,” screen Aether said. “Actually, in my spare time, I’ve been trying to write a tragedy. A proper one — I imagine it will be performed in a stage play than in front of a kamera. I used to do community theater in college, so it will be good to go back to my roots. But I’m an optimist at heart. Most of the time, I write happy endings because I want people to see themselves in the stories I write.”
Albedo’s eyes shined with tears. “Even when he’s not around, he’s still trying to cheer us up.”
In his little black notebook, Aether copied words from poets and wrote down names of people he knew. He borrowed other people’s words to write unsent letters to his loved ones.
The last poem, written a month before the accident, and read four months after, is addressed to Lumine.
A basket of apples brown in our kitchen,
their warm scent is the scent of ripening,
and my sister, entering the room quietly,
takes a seat at the table, takes up the task
of peeling slowly away the blemished skins,
even half-rotten ones are salvaged carefully.
She makes sure to carve out the mealy flesh.
For this, I am grateful. I explain, this elegy
would love to save everything. She smiles at me,
and before long, the empty bowl she uses fills,
domed with thin slices she brushes into
the mouth of a steaming pot on the stove.
What can I do? I ask finally. Nothing,
she says, let me finish this one thing alone.
Lumine tears the page from his notebook and crumples it up, throws it in the bin. She reminds herself that this was written before the accident. He was probably writing about the way she showed her care for him.
But how dare he? How dare he write to her like he wants her to… to...
(She did peel those apples from the Sunday Market. Made apple pie, boiled the cores and peeled skin, made the most out of everything the fruits had to offer, bruised and near-rotting though they were. But—)
In that moment, Lumine spies the ghost of her brother overshadow her reflection in the glass window. “Even half-rotten ones are salvaged carefully,” she reads, but it’s Aether’s image that mouths the words in the reflection. “For this, I am grateful.”
Who does Aether think she is? Who does he think he is to ask this of her? He’s the golden child. Lumine is his shadow. That’s how they decided they would be. She was the moon to his sun. She could never just finish things the things he left behind, could she?
Oh, but this is very much how Aether would think. He’d do anything for his dreams, even go as far as to ask his sister to accomplish them in his stead. So long as they are fulfilled, even from beyond the grave. And he would be grateful, wouldn’t he? Because Lumine could do it. Lumine salvages everything that can be saved, even when they’re rotting and dying. Even if they’re six feet deep in the ground.
Lumine didn’t kill him, but if she doesn’t keep his dreams alive, she might as well have. Aether still has bountiful dreams he left behind for her to carry through.
And his dreams are beautiful indeed. Lumine loves her brother for them. Aether dreams, and Lumine saves. That’s how they always worked. Lumine brings people from the brink of death for another chance at life; an anti-psychopomp. But Aether, with his words and his stories, is the one who inspires. He makes you believe in a life worth living.
Life has a funny sense of humor, then, to cut him off from the same experience.
An hour later, Lumine takes the torn paper out from the bin and smooths it flat. The creases will never leave. She can’t undo them just as she can’t undo death. But the words are still here, and Aether’s dreams are still here. That has to be enough.
Lumine didn’t kill Aether, no, but she never kept him alive after his death. Four months after the funeral, Lumine still doesn’t have that last manuscript he wanted to show the world. She remembers him talking about it. He wanted to flex his creative muscles, wanted to do something different from his usual stories.
Everyday, the calling card and the memory of brilliant teal eyes loom over her. But she’s not ready to face it, not yet, not alone. Not until—
One step at a time. She knows what Aether wants her to do, but Lumine can only be so brave when she’s alone. She can’t do this alone.
With a trembling heart and a grief-driven bravery, Lumine spends the next two weeks in Snezhnaya and calls up an infamous underground doctor.
She returns to Mondstadt with stitches marring her left hand, one finger lighter than the rest of her tanned skin, sun-kissed from the days she spent outside as a first responder. The nail is decorated with bright yellow nail polish.
—
Albedo will be leaving soon. Lumine can do nothing about that. He’s heading for Sumeru, she thinks. He can’t move on if he stays here. Aether wouldn’t want to tie him down.
“You can come with me,” he tells her. Sometimes, on the days he stares too long at her mismatched fingers, he comes close to pleading. “If you want. You don’t have to stay there for long, but getting away from all this might help. It’s okay to leave your grief behind, even for just a little while.”
Lumine shakes her head, because now she has something to do. Aether said so, in his poem. This elegy would love to save everything. Let me finish this one thing alone. So how can she go? Who will publish Aether’s manuscript? Who will take care of Aether’s garden, and his charity work? Who will keep watch of the house? The dust will build, and the air will go stale, and Aether never liked the house to be lonely.
Albedo must think her crazy. Lumine can’t bear the pity in his eyes, ill-disguised as they are. Perhaps he never meant to hide them at all. Albedo is not that type of person — after all, how else did Aether fell in love with him? He loved straightforward people.
Still, Albedo is right. Grief doesn’t have to stay.
So at night, Lumine lays on her pillow and dreams of how she can keep Aether alive. His dreams, if not his body, because his body is decaying six feet deep underground. So it’s up to Lumine to finish things for him. She loves him so, so much, after all.
It is fortunate, then, that Lumine loves the way he dreams.
Unyielding, awful, and all-consuming.
She starts with his garden. A simple task. She just needs to take care of Aether’s plants, and they have been looking rather lonely without their gardener. Albedo has been keeping them healthy all this time, but he’s leaving soon. So she feeds them fertilizer and waters them everyday until the leaves turn yellow and crisp, for which Albedo gently scolds her for. One of the more delicate flowerpots wither from her care.
“You need to leave them alone,” he tells her. “They’ll be fine without water for a few days. They like to be left alone.”
With great reluctance, she leaves them alone for the day and spends the rest of her hours reading poems. She writes her first letter to Aether, a response, folded neatly in between the bouquet of cecilias that she leaves by his grave the next morning.
You died just hours ago.
Not suddenly, no. You'd been dying so long
nothing looked like itself: from your window,
fishermen swirled sequins;
fishnets entangled the moon.
If only I could go to you, revive you.
You must be a little alive still.
“What can you do?” she recites. She already has his poem memorized. “Nothing, I say. So let me finish this alone.”
The grave doesn’t respond. Of course it couldn’t. There’s nothing Aether can do now. Six feet in the ground. Can Aether even hear her? The thought weighs heavily in Lumine’s mind.
“But I failed already. I killed one of your plants,” she confesses. “I’m sorry. Maybe it will keep you company, now that it’s gone. But I’ll try to be better, this time. I’ll save the rest of them.”
Lumine vows, from this day on, that she will live his legacy for both of them.
This elegy would love to save everything.
—
On the day Albedo leaves Mondstadt, Lumine resigns from the knights and signs up for acting classes. She’s no stranger to the world of theater, but… it’s been a while.
There are scribbles at the back of Aether’s little black notebook. Scratched lines, discarded paragraphs, the debris that remained from when he sketched out the outline of his final, unpublished script. Usually, Aether wrote for tv and film. But for this story, he intended it for the stage. A proper play.
It takes Lumine back to the days when they were still in college, participating in community theater. She likes to think that he wrote this play for her. He always wanted her to star in one of his stories.
“I always write them with you in mind. There’s no one I trust more,” he used to say. Then, he would joke, “One day, I’ll write a script that will compel you to act for me. Just you wait.”
Unorganized scraps of the final story fill up the back half of his notebook — character notes, themes, sources of inspiration, quotes from other books, snippets of dialogue. Cruelly, it is the most compelling script Aether wrote. Lumine regrets not indulging him when he was still alive.
Because finally, with this, Lumine can see herself in Aether’s story.
Lumine steels herself in front of the mirror. “I’ll act this out for you, Aether. Just you wait.”
Her (His? Their?) little finger tingles. A wave of calm settles on her, relaxing her body for the first time in months. This feels right.
Aether smiles back at her from her reflection, proud and encouraging.
ACT I: MADNESS (scene one; first draft)
Four years pass.
The bass is everywhere. It thrums in her skin, in her bones. In Aether’s bones, too.
Lumine is no longer a stranger to the world of celebrity shindigs — a necessary part of working in the entertainment industry, an event that masks as partying but functions as networking with your future coworkers. Half the time, it’s genuinely as fun as they make it out to be.
But Lumine has long avoided going to one of Venti’s infamous afterparties until now. They say that those are always fun. All play, no work.
Lumine isn’t here to have fun though. After four years of preparation, she is here to finally put Aether’s last dream into motion, and the first step is to hold Venti to the promise he made years ago at the funeral.
More importantly, parties are an opportunity to scope out the person Lumine is looking for. Someone who is her opposite on the stage: the comedy to her tragedy, a fighter to her lover, a character driven by agency instead of fate. Someone who is governed by—
Still, the bass thrums. Lumine finds her little finger tapping to the rhythm of the beat. Aether must have missed this. The music, the dancing, the socializing. It must be lonely, to only exist in reflections and shadows, as an extension of another body.
She permits herself one dance and lets the percussion of the music move her limbs. The dance floor pulls on her, like a magnet. Bodies move to and fro, to and fro, and by the time the song ends, Lumine feels lighter than when she stepped into the room. Loose, like she just shook off invisible weights dangling from her head.
Someone taps her on the shoulder and then she’s face to face with brilliant teal eyes. They are eye-catching under the strobe lights.
“I was wondering when we’d have the chance to meet again. You’ve been avoiding me, Lumine.” Venti smiles at her, sounding amused.
“Are you here to party, or to mourn?”
“Hello, Venti. We meet again. You said you’d keep Aether’s manuscript for me until I’m ready.”
“Are you?”
Lumine shrugs. “I’m here, aren’t I?”
“You could have texted me if you just wanted the manuscript. My number hasn’t changed. I could email it to you anytime.”
“Maybe I want to do both. Who says you can’t mourn while you’re partying?”
Venti hums; studies her. Whatever he finds must have intrigued him enough to stretch out a hand. “Very well. Since you came all the way out here, mind if I keep you company? It’s not good to party — or mourn — alone.”
Lumine doesn’t decline. Venti is a bit of a mystery to her, a puzzle she didn’t feel brave enough to figure out until she’s ready to face Aether’s final play. She knew of him — of the music he produces and the parties he throws. She knew that Aether was friends with him since the beginning of both of their careers.
Aether must have trusted him immensely if he left his little black notebook of poetry with him.
Venti leads her to one of the booths, where a young man with blond hair is already sitting, watching the room with clear eyes. Upon seeing Venti and Lumine, he procures two glasses and a bottle of expensive wine from under the seat for them. He takes out a familiar-looking pill from his jacket pocket and swallows it dry.
“Mika, don’t take more than you can handle,” Venti scolds gently. Almost motherly. “I know your limits.”
“I’m not overdoing it,” Mika says, though he does throw Venti an apologetic look.
“I know.” Venti slides into the booth and begins pouring wine into the glasses. “Have you confirmed who will be attending the next sparasso?”
“I’m working up to it.” Mika sighs, looking back at the dance floor as if he’s warring with himself over something. Then he stands up and takes a deep breath, bracing himself for his inevitable task. “I’m sure Tartaglia will confirm, at least. I’ll follow up on the rest of them now. It’s nice to finally meet you, Miss Lumine.”
He disappears into the party, leaving Lumine alone with Venti.
“That was my assistant, Mika. He’s a good kid, but he can be conscientious at times. It’s for the best though, since I’m pretty scatterbrained myself. I don’t know what I’d do without him.” Venti slides the glass of wine towards her. “Do you drink?”
Lumine raises an eyebrow. “Not even vodka? Wine isn’t exactly the choice of drink for ragers.”
“It’s a drink for celebration and death. I thought it would be fitting for our most unique occasion.” Venti waves his own glass with a flourish before taking a sip.
In his poetry notebook, Aether described Venti as the swoony type; long hair, bedroom eyes, cheeks like wine. A free, uncontrollable spirit. Mondstadt’s celebrity culture share the same impression.
Lumine thought she would find him dancing wildly, or playing party games, or getting high. But this booth is a quiet bubble, a sanctuary amidst the chaos around them. Venti watches the dance floor serenely, in no particular hurry to join or empty his glass. There’s something gentle about him. Nurturing.
Lumine blurts out, “You’re different from who I thought you’d be.”
“What did you think I was like?”
“From the stories I’ve heard? A party animal.”
“We’re all animals here. But I like to make sure everyone is having fun. It’s sort of my job, you see.” There is a delighted twinkle in his eyes as he says this. “But I suppose I do have a reputation to keep. Nobody leaves my parties dissatisfied.”
“So I’m your new pet project then? Can’t have me giving your party a bad review?”
“You could loosen up a bit,” Venti agrees. “Aether was never like this when he was still around.”
“Did Aether ‘loosen up’ often?”
“I’d say it’s more like he let himself become more honest. More true to himself.”
Venti smiles at the fond memories this brings up. It makes Lumine want to know. “Tell me about him. What was your relationship like?”
Venti met Aether at a hobby club. They were both just starting out then; Aether in the writer’s room for a tv show, and Venti busking on the streets to promote his upcoming debut. Venti frequented the club for fun, while Aether visited every now and then for stress relief.
Lumine vaguely recalls Aether mentioning this to her before in the early days, but it never seemed important enough to remember. He doesn’t talk about it often enough for Lumine to recall what exactly their shared “hobby” was.
“The entertainment industry can really drain you, you know? So we needed an outlet to let off some steam.”
“What did you do together? In that club? Aether never told me he had other hobbies.”
“Why don’t you visit me at my studio sometime? It’s easier to show you.”
Venti muses over his drink. The glass is already empty, so he fills it with more wine than it contained earlier. “He gave me a cactus once. Said that it’s the perfect plant for me, since I wouldn’t be able to kill it.”
Lumine frowns down at her own glass, still untouched. The wine beckons her; a dark, deep red that shimmers with the party lights.
“I killed his plants,” she shares. “All of them. I tried to keep them alive, but there was always something going wrong. Fertilizer burn. Watered them too much. I don’t know, I think I did too much. It’s funny, now that I think about it. You can love something to the point of ruin.”
“He liked to keep low-maintenance plants. I think they just didn’t fit with the way you care. There is nothing wrong with it. You were simply incompatible.” Venti clinks his glass with hers. “Boundless love is something to treasure. Too many people show restraint these days, you know? I find it admirable.”
“Sure, it sounds amazing, but it’s hard to handle that kind of love. It’s suffocating. It killed the plants. I don’t know who fits this kind of love.”
“I wouldn’t find it suffocating.” Venti’s lips quirk up, like he remembered an inside joke he’s not interested in sharing. “We could fit together.”
“Could we?” Lumine tilts her head. How would he know? The first and last time Lumine saw Venti was four years ago, during Aether’s funeral. “You don’t know me.”
“I know a little bit about you, now that we've met properly. That should be enough.”
Lumine doesn’t realize when it happened, but she somehow scooted closer to Venti inside the booth. To hear him better, probably. She can smell the faint cologne on him — something sweet and bitter, like dried fruits.
“What have you heard, then?” she asks.
“I know that you like to star in tragic films, in contrast to your late brother’s penchant for happy endings,” Venti says, counting facts with his fingers. “I know that you were once a paramedic before you were an actress. And I know that you haven’t had a drink since you entered this room. Do you drink?”
“A little.”
Venti slides the glass of wine again. “It’s a special blend. You won’t get a hangover from this one, I promise.” He waves jazz hands in the air, grinning. “This bottle is like magic.”
Lumine’s left pinky twitches. Perhaps Aether missed this as well. The drinking, the companionship. There is no judgement in Venti’s presence, just a soothing invitation that holds no expectations. He would not be offended if Lumine decides not to drink.
But Aether would have, so Lumine does. The wine flows smoothly down her throat. Sweet and bitter and a hint of metallic. Venti regales her with more stories of his friendship with Aether; of the times they’d commiserate over the writing process; of the many, many concerts and afterparties they’ve gone to. They, too, bonded over poetry.
There is a warm feeling in Lumine’s chest that grows with each story. Aether is missed. And yet, she doesn’t want to mourn that. Aether was loved. She wants to be happy about it. Her head starts to feel like cotton, but her heart feels so, so light.
She sips; her glass is full again and oh — when did Venti refill it?
“Have you read his notebook?” Lumine asks. Venti shakes his head.
“Aether dedicated a poem for you. I remember how it goes. Come to me now: loose me from hard care and all my heart longs to accomplish, accomplish. You be my ally.”
Lumine is floating. She should be looking for… something. Someone? She can’t remember that now. She’s supposed to find someone, but now she’s just reciting poetry. One of the short ones from Aether’s little notebook. It’s nice.
Venti is saying something, reciting a poem back in response. Lumine has never heard it before. She wants to memorize it. “How does that go? Say it again.”
“She who did not come, wasn’t she determined nonetheless to organize and decorate my heart? If we had to exist to become the one we love, what would the heart have to create? Hm, I’ll text you how the rest of that goes, but I think that poem suits you.”
“How so?”
“You have a lonely gaze. You look like you want to be someone else right now.”
The words sink like an anchor, and Lumine knows she will be thinking about this for hours later. Her hands itch to do something in response. To hold his hand, or to strangle him, Lumine’s not sure. All she knows is her body growing restless. Her mind wants to wander to somewhere else less painful.
Venti pulls her out of the booth. “Come on. We’ve mourned long enough. It’s time to party.”
“Maybe I still want to mourn,” Lumine says, petulantly, but she finds that she doesn’t mean it. Shouldn’t she mean it? She never stopped mourning.
“We can reminisce again later. I will let you mourn as much as you want. But for now, dance with me.”
Venti leads her to the center, where the bodies sway to and fro, to and fro. It’s hot and sweaty and dark and easy to get lost in. Easy to lose one’s mind.
It’s perfect.
Lumine smiles and lets herself get caught in Venti’s orbit, dancing, laughing, and she can’t even remember what she’d been sad about earlier. She was… grieving, wasn’t she? It feels so foreign now when the beat of the music is dictating her heartbeat.
Lumine vaguely recognizes the song. It’s a club remix of Venti’s music — not the one he personally sings in his concerts, but one of those he composed and produced and sold for other singers to perform.
“Life is one big party!” Venti shouts, and then the crowd is shouting with him, chanting the lyrics in unison. Lumine shouts with them.
“Pa-pa-pa-pa-par-taaaay!”
It’s building up, going higher and faster, higher and faster, and the drop is going to be so sick that the dancers around them are collectively waiting with bated breath, anticipating, working themselves into a frenzy. The lights are there and then not and then there, and then there’s just shadows and heat and neon lights flashing, flashing, and then the beat drops and everyone is jumping and thrashing more than dancing and fuck. Fuck. Lumine is swept into it. She lets herself be swept into it. They all move as one organism.
Venti is closer now, so much closer, body against body that Lumine wants to breathe him in. His smile is charming, wine-stained. Easy.
Lumine feels easy, calm and ready to take the whole world all at once. She feels like floating. Like, like— “I can do anything right now,” she says, feeling the need to tell Venti. There’s no way Venti could have heard her with the raucous around them.
“Ah, you’re that kind of drunk, huh,” Venti answers back, grinning, and oh, so that’s what she’s feeling. Drunk. She shouldn’t be able to hear him either, but his voice is as clear as the waters from Springvale. He spins her around, but in the tight space between bodies, all he ends up doing is pull her against him. “Alright. What do you want to do then?”
It strikes her, suddenly, that she found the person she’s looking for. The one who will bring Aether’s play to life, with her. The hero to her tragedy.
It has to be Venti.
Lumine grins and hooks an arm around his shoulders. “Let’s go up to the roof. I want to ask you something.”
She leans close to whisper her own invitation, confident that he will understand his role. He will say yes. For, surely, Venti is a man governed by “Eros.”
—
Lumine blanks out after that. She might have had a couple more glasses, they might have sneaked onto the roof even though the building definitely wouldn’t have allowed it. There was a cool breeze, and Venti joked about something, but she doesn’t remember what they talked about, or how she came home. Vaguely, all she remembers is complaining about how there’s too many lights in the city to see the stars. You can’t see the Northern Crown constellation from here.
But true to Venti’s word, his wine is made of magic because Lumine wakes up in her bedroom with a clear head. No nausea, no headaches, completely sober. There’s two new messages on her phone. The first contains a familiar poem from last night. The other is an email with a PDF attachment.
There it is. Aether’s final manuscript.
Lumine spends the whole morning reading. By the time she reaches the last page, she despairs.
Just as how Lumine has no memory of what else she talked about with Venti on the roof — except for a vague recollection of him saying yes to her offering a role to play — the script provides a similar non-conclusion.
The script has no ending. Aether never finished the story.
END DRAFT.
fic inspiration:
the myths of dionysus as god of wine, theater, and madness; as well as his connection to orphism, death and rebirth, and so on. I have a whole spreadsheet of research materials, but the OSP video is the best primer
cult of dionysus (song) by the orion experience
description of dionysus from the bakkhai (translated by anne carson): "swoony type, long hair, bedroom eyes, cheeks like wine"
the temptation of thanatos (タナトスの誘惑) by hoshino mayo, translated by latteandcookies. this is the inspiration for the play aether wrote. it's a short story, but cw for suicide. fun fact: it's also the inspiration for yoasobi's song racing into the night
240520 UPDATE: I decided to make public the spotify playlist related to this fic.
poetry references:
[you fit into me] by margaret atwood
growing around grief by lois tonkin
I borrow moonlight... by saikaku ihara (his death poem; from the book, japanese death poems compiled by yoel hoffmann. page 268)
mizuta masahide's death poem (also found in japanese death poems, page 234)
my sister, who died young, takes up the task by jon pineda
on wanting to tell about a girl eating fish eyes by mary szybist
come to me now: loose me from hard care... fragment by sappho, translated by anne carson (page 5 of if not, winter)
blank joy by rainer maria rilke
#fic: like a hook into an eye.#scraps and drafts#this was a pain to format on tumblr.........#i gave up on formatting the actual play script and just took screenshots lol#i can format it for AO3 but. i don't trust tumblr's editor to not fuck it up#so if the formatting here looks wonky uhhh. sorry about that#tumblr always fucks up the formatting
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Cashew Nuts Farming in India
Exploring Cashew Nut Farming in India: A Simple Guide
Imagine vast fields under the Indian sun, where farmers nurture trees bearing cashew nuts, a popular snack enjoyed worldwide. Let's delve into the world of cashew nut farming in India, where hard work and nature come together to produce these delicious treats.
Where It All Began:
Hundreds of years ago, Portuguese explorers brought cashew trees to India. Since then, these trees have thrived in states like Maharashtra, Kerala, Karnataka, and Goa, becoming an essential part of Indian agriculture.
How Cashew Nuts Grow:
Cashew nut farming starts in the rainy season, usually from June to July. Farmers plant cashew seeds or grafts in well-drained soil. Cashew trees need warmth and moisture to grow well.
These trees bear cashew apples, each with a single nut attached to its base. The cashew fruit grows slowly, and it takes months for it to ripen.
Harvesting and Processing:
Harvesting cashew nuts needs careful handling. When cashew apples ripen and fall to the ground, skilled workers collect them. Then they separate the nuts from the fruit.
Removing the outer shell of the cashew nut is a bit tricky because it contains substances that can cause skin irritation. After that, the nuts go through roasting, shelling, and drying processes to keep them fresh.
Challenges and Solutions:
Cashew nut farming faces challenges like changing market prices, pests, diseases, and not having enough workers. Also, climate change affects cashew trees, making it harder to grow them.
Farmers are finding new ways to deal with these challenges. They use modern techniques like drip irrigation and organic farming. They also learn how to manage pests without using harmful chemicals.
India's Impact on the World:
India is a big player in the global cashew nut market. The country has vast cashew orchards and farms that produce nuts for people worldwide. Cashew nuts are used in many dishes and snacks, loved by people everywhere for their creamy taste.
In Conclusion:
Cashew nut farming in India is a story of hard work, tradition, and innovation. It's about farmers who dedicate their lives to growing these delicious nuts. As we enjoy cashew nuts, let's remember the farmers whose efforts make it possible.
In the fields of India, where the sun shines bright and cashew trees sway in the breeze, the journey of cashew nut farming continues. It's a story of resilience and the beauty of nature, shared with the world through every crunchy bite.
krishnavstore.com
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Growing Bioengineered Artificial Skin Market Poised to Witness Robust Expansion During 2023-2030
Bioengineered artificial skin refers to lab-grown human skin that mimics natural skin. It helps treat severe burns and other wounds by protecting tissues from infections and fluids loss. Significant advances have been made in developing bioengineered artificial skin that closely resembles natural skin tissue in composition, function and appearance. The artificial skin substitutes facilitate faster healing and avoid complications associated with skin grafting from other parts of the body. Growing prevalence of burn injuries and skin disorders has increased the demand for these skin substitutes globally. The global bioengineered artificial skin market is estimated to be valued at US$ 3.32 Billion in 2024 and is expected to exhibit a CAGR of 16% over the forecast period 2023 to 2030.
Key Takeaways
Key players operating in the bioengineered artificial skin market are Genoskin, Smith and Nephew Inc., Genzyme Biosurgery, Vericel Corporation, AROA BIOSURGERY LIMITED, Integra LifeSciences Corp, COOK BIOTECH, Mölnlycke Health Care AB, Avita Medical, MiMedx Group, Inc., and Organogenesis Holdings Inc.
Market Trends
The growing trend towards cell-containing skin replacements have moved regenerative medicine forward. Researchers are developing skin substitutes containing keratinocytes, melanocytes and fibroblasts to mimic natural skin better.
Tissue-engineered skin substitutes are increasingly common over biosynthetic skin grafts. They mimic the complexity and biomechanics of natural skin closer than acellular skin substitutes. Advances in biofabrication techniques have enabled the large-scale production of tissue-engineered skin grafts.
Market Opportunities
The development of bioengineered skin with functional appendages like hair follicles, sebaceous glands and sweat glands presents lucrative opportunities. It can help restore skin's barrier function better and improve aesthetic outcomes.
Personalized bioengineered skin using patient-specific cells offers strong market potential. 3D bioprinting and tissue engineering approaches allow manufacturing skin grafts tailored for individual patients' anatomy and physiology.
Impact of COVID-19 on Bioengineered Artificial Skin Market
The COVID-19 pandemic has significantly impacted the bioengineered artificial skin market. During the initial outbreak and lockdowns imposed worldwide, demand for artificial skin was low as non-essential medical procedures were postponed. Supply chain disruptions and shortage of raw materials also hindered production activities. However, post lockdowns, the demand started picking up again as elective surgeries resumed. The pandemic highlighted the importance of this market as artificial skin is used for treating severe burns and other traumatic wounds.
North America Region for Bioengineered Artificial Skin Market
The North America region accounts for the largest share of the global bioengineered artificial skin market in terms of value. This is primarily attributed to factors such as the rising incidence of burns and traumatic injuries, growing elderly population susceptible to chronic wounds, favorable regulatory environment, strong healthcare infrastructure and higher adoption of advanced treatment options. Countries like the United States have several registered skin graft products and ongoing clinical trials.
Asia Pacific as the Fastest Growing Region
The Asia Pacific region is poised to grow at the fastest pace in the global bioengineered artificial skin market owing to a swiftly increasing patient pool, rising medical tourism and improving access to healthcare. Rapid economic development and rising affluence have been instrumental in market growth. China, India and other ASEAN countries are witnessing significant development of healthcare facilities and increasing healthcare expenditures.
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4 Key Trends Shaping 3D Printing in India Today
3D printing in India is changing manufacturing and product development. It starts with rapid prototyping and goes to making finished end-use parts. This revolution is happening in various industries. Additive manufacturing has become easier and cheaper due to improvements in materials, hardware, software, and applications. There are many reasons why industrial and desktop 3D printers in India are becoming more popular.
Understanding important changes helps your business use 3D printing and stay competitive.
Demand for Mass Customization
Indian consumers desire personalized products. They can customize designs and produce them on demand using Online 3D Printing India****. Customers want personalized products. These products include custom orthotic insoles, prosthetics, sports equipment, fashion accessories, and commemorative statues.
Nike and other big brands now make custom shoes using 3D printing. Companies can increase their sales revenue and market share by expanding their 3D print services. This expansion allows them to provide mass customization and just-in-time manufacturing, which meets consumers' rising expectations.
Growth of 3D Bioprinting
3D bioprinting is growing rapidly in the medical field. It involves printing live cells to make tissues and organs for transplantation. Indian researchers are making technological advances. They are creating 3D bioprinted skin for grafts. These grafts are used in burn treatments.
The global 3D bioprinting market will grow by 28% annually and reach $1.7 billion by 2024. Indian technology leaders have the opportunity to benefit from these innovations. The population is aging, and there is a growing demand for regenerative treatments.
Increasing Affordability
A few years ago, industrial 3D printing services were expensive, costing over Rs 100,000. This made it difficult for small businesses to use them. Today, you can buy professional desktop printers for under Rs 20,000. They offer great quality and reliability.
Hobbyist printers are available for a few hundred dollars or can be rented cheaply from online services. 3D printing is now more affordable for small businesses and entrepreneurs in India. The costs of acquiring the technology have decreased, and there are more materials and design software options.
Rise of 3D Printing Marketplaces
Online marketplaces for 3D printing in India have grown rapidly. They are now affordable and easy to use. This has enabled instant access to manufacturing capacity. Customers can upload 3D model files. They can get quotes for production. They can get quotes from hundreds of providers nationwide.
Users can easily get their parts 3D printed and delivered within days with just a few clicks. Service providers can access a large customer base easily and at low costs using these platforms. Tractus3D, Anzyz, Grabcad, and Aniwaa are popular 3D printing companies. They are connecting buyers and sellers of 3D printing services in India. This is beneficial for everyone involved.
Conclusion
Companies in India, from startups to big corporations, see the potential of 3D printing. They believe it can improve all sectors' manufacturing, supply chains, and customer service. A3DXYZ offers easy access to high-quality 3D printing services online India and worldwide. They provide premium industrial printing at affordable prices. Contact us today to improve and accelerate your manufacturing.
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Skin Replacement Solutions: Bridging the Gap for Chronic Wounds and Burn Victims
Introduction
The global skin replacement market has experienced remarkable growth in recent years, driven by factors such as an aging population, an increasing number of patients with chronic wounds, advancements in medical technology, and the rising demand for cosmetic procedures. Skin replacement therapies and products have become pivotal in the fields of wound care, burn management, and aesthetic medicine. This article explores the dynamics of the skin replacement market, its key drivers, challenges, emerging trends, and the promising future of this industry.
Market Overview
Skin replacement, a therapeutic approach aimed at restoring damaged or lost skin, plays a crucial role in wound management and the treatment of various skin-related conditions. It encompasses a wide range of products, including dermal grafts, artificial skin substitutes, and tissue engineering products. These products are utilized in the treatment of acute and chronic wounds, burns, and for cosmetic purposes.
Key Drivers
1. Aging Population: The global population is aging, leading to an increased prevalence of chronic wounds, pressure ulcers, and diabetic foot ulcers. Skin replacement products are essential in the management of these conditions, fostering market growth.
2. Advancements in Medical Technology: Innovations in tissue engineering and regenerative medicine have resulted in the development of more advanced and effective skin replacement products. These technologies are enabling the creation of biocompatible and functional skin substitutes.
3. Rising Cosmetic Procedures: The desire for youthful and flawless skin is driving the demand for cosmetic procedures like dermal fillers, botox, and skin grafts. The skin replacement market is expanding to cater to this aesthetic segment.
Challenges
1. Regulatory Hurdles: The skin replacement market is subject to stringent regulatory approvals due to the sensitive nature of its products. Ensuring safety and efficacy is a significant challenge for manufacturers.
2. Cost and Reimbursement Issues: Skin replacement procedures and products can be expensive. Reimbursement challenges and affordability issues hinder patient access to these treatments.
3. Competition: The market is highly competitive, with numerous players vying for market share. This competition can result in pricing pressures and a need for continuous innovation.
Emerging Trends
1. 3D Bioprinting: 3D bioprinting technology is transforming the skin replacement market. It allows for the precise creation of skin tissue, including vascular networks, to enhance graft integration and function.
2. Stem Cell Therapy: Stem cell-based skin replacement is gaining momentum. These therapies promote tissue regeneration and have shown promising results in wound healing and scar reduction.
3. Personalized Medicine: Advances in genomics and personalized medicine are enabling the tailoring of skin replacement therapies to individual patient needs, resulting in more effective treatments.
Future Outlook
The future of the skin replacement market appears promising, with continued growth expected. The aging population will ensure a sustained demand for wound care products and anti-aging solutions. Advancements in biotechnology, regenerative medicine, and 3D printing will lead to more innovative and effective skin replacement products.
Additionally, the ongoing research into the development of skin substitutes with integrated sensory functions and improved vascularization will further expand the applications of skin replacement therapies. The market is likely to witness increased collaboration between researchers, clinicians, and industry players, fostering a multidisciplinary approach to address the complex challenges of skin replacement.
In conclusion, the skin replacement market is evolving rapidly, driven by demographic changes, technological advancements, and changing consumer preferences. Despite regulatory challenges and competition, the industry's future looks bright with the promise of personalized treatments, 3D bioprinting, and stem cell therapies. As this market continues to expand and innovate, it will contribute to improved wound care, burn management, and aesthetic procedures, benefiting both patients and the healthcare industry as a whole.
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Patient Access Solutions Market Size, Industry Share, Growth Demand, Supply Chain, Trends Future Outlook, Forecast 2030
The latest market report published by Credence Research, Inc. “Global Patient Access Solutions Market: Growth, Future Prospects, and Competitive Analysis, 2022 – 2030. The patient access solutions marketplace is expected to attain revenue of USD 3,745.16 million by 2030, growing at a CAGR of 6.00% from 2023 to 2030. In 2022, the marketplace revenue was recorded at USD 2,348.96 million.
The Significance of Collagen Tissue Engineering
Collagen, often referred to as the "building block" of our bodies, plays a pivotal role in maintaining tissue structure and function. As a naturally occurring protein, it serves as the scaffolding for our skin, bones, tendons, and organs. However, injuries, diseases, and aging can compromise the integrity of collagen-based tissues. This is where collagen tissue engineering steps in as a transformative solution.
Patient access solutions market dynamics refer to the ever-evolving landscape of technologies and strategies aimed at improving patient access to healthcare services. This dynamic market is driven by several factors, including the increasing demand for efficient patient management systems, rising healthcare costs, and the growing emphasis on delivering personalized care. As technology advances, patient access solutions are becoming more sophisticated and comprehensive, encompassing various aspects such as appointment scheduling, insurance verification, pre-registration processes, and self-service options. These solutions aim to streamline administrative tasks while enhancing patient experience and reducing wait times.
Our Cutting-Edge Approach
Biomimetic Scaffolds
These scaffolds provide an ideal environment for cell growth and tissue regeneration. Our state-of-the-art 3D printing technology ensures precise control over scaffold design, allowing us to tailor solutions for specific applications.
Biocompatible Materials
We are committed to ensuring the safety and effectiveness of our products. Our materials are rigorously tested for biocompatibility, ensuring they seamlessly integrate with the body's own processes. This reduces the risk of rejection and inflammation, making our engineered tissues a reliable choice for patients.
Applications in Medicine
Collagen tissue engineering has found wide-ranging applications in the field of medicine, revolutionizing treatments and procedures across various disciplines.
Regenerative Medicine
In regenerative medicine, our engineered collagen tissues have opened new doors for treating injuries and degenerative diseases. From cartilage repair to skin grafts, our solutions offer hope and healing.
Cosmetic and Plastic Surgery
Cosmetic and plastic surgeons are increasingly turning to collagen tissue engineering for procedures such as breast augmentation and facial reconstruction. The natural look and feel of our engineered tissues have garnered acclaim in the industry.
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Orthopedics
In orthopedics, our biomimetic scaffolds are being used to accelerate bone healing and improve joint function. Patients experience faster recovery times and enhanced mobility.
Conclusion
As pioneers in collagen tissue engineering, Credence Research continues to drive innovation and excellence in healthcare. Our commitment to pushing the boundaries of what is possible is at the core of everything we do. With biocompatible materials, advanced 3D printing technology, and a deep understanding of regenerative medicine, we are proud to offer solutions that are changing lives for the better.
In the ever-evolving landscape of healthcare, we remain dedicated to staying at the forefront of collagen tissue engineering. Our mission is to empower healthcare professionals with the tools they need to provide the best possible care to their patients. Together, we are shaping a brighter, healthier future.
Why to Buy This Report-
The report provides a qualitative as well as quantitative analysis of the global Patient Access Solutions Market by segments, current trends, drivers, restraints, opportunities, challenges, and market dynamics with the historical period from 2016-2020, the base year- 2021, and the projection period 2022-2028.
The report includes information on the competitive landscape, such as how the market's top competitors operate at the global, regional, and country levels.
Major nations in each region with their import/export statistics
The global Patient Access Solutions Market report also includes the analysis of the market at a global, regional, and country-level along with key market trends, major player analysis, market growth strategies, and key application areas.
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Skin Graft Market Outlook, Global Outlook & Forecast 2023-2032
Market Synopsis of Global Skin graft Market:
In 2022, the skin graft market was estimated at USD 4.00 billion. The skin graft market is expected to increase from USD 4.28 billion in 2023 to USD 7.36 billion by 2032, with a compound annual growth rate (CAGR) of 7.01% over the forecast period (2023-2032).
Key players of Global Skin graft Market:
Key players profiled in the report are Organogenesis, Inc., Specmed Medical, Stratatech Corp, Tissue Regenix Group PLC, Avita Medical, Convatec Inc., Medrotonic, Coloplast, B. Braun Melsungen, zimmerbiomet, Stratatech Corporation, Zimmer Biomet and others.
Current Industry Trends:
U.K.’s National Health Service researchers are expected to launch a liquid skin dispersing device which contains a regenerative epithelial suspension which mimic natural skin and reduce wound healing times
Allograft skin graft is expected to lose market share in favour of xenogeneic and prosthetic segments. The advancements in skin graft technology such as biocompatibility and biomimetic material is a reason for the expected development coupled with the drawbacks of allografts such as large surgical footprint
Mergers and acquisitions are ripe as the skin graft market outlook is highly technology oriented with large development cost and times. To cut short development efforts and to take advantage of complementary specialities of other companies are the cause of the mergers and acquisitions. For example, Mallinckrodt plc, entered into a merger agreement with Stratatech Corporation in August 2016 to take advantage of reduced development efforts for StrataGraft regenerative skin tissue and a technology platform for genetically enhanced skin tissues.
Start-ups are a growing trend, as a company with proprietary technology will have an advantage over a larger competitor due to low volume and high value nature of the product, which negates the economics of scale advantage of a larger company.
Market Dynamics of Global Skin graft Market:
Drivers
Rise in the cases of risk factors such as accidents, skin infections such as necrotizing fasciitis or purpura fulminans, burns, cancer, surgeries and others. According to WHO, burns are a leading cause of public health issue causing approximately 265000 deaths annually. The global burn care market size is approximately USD 1.5 billion in 2016.
Technical advancements in surgical instruments such as development of electrical dermatome and drum-type dermatome which has resulted in greater accuracy and control.
Growing occupational hazards such as electricity, high temperatures, machinery and others
Restraints
Complications such as infection, pain and hospital stay
High cost of treatment
Lack of healthcare infrastructure in developing regions
Rejection and immune reactions which can be fatal
Segments of Global Skin graft Market:
The global skin graft market report is segmented on the basis of graft type, graft thickness and applications. Graft type - autologous, isogeneic, allogeneic, xenogeneic and prosthetic.
Graft thickness - split-thickness, full-thickness and composite graft.
Applications - extensive wound, burns, extensive skin loss due to infection, skin cancers and others. Equipment - dermatome (knives dermatomes, drum dermatomes, electric dermatomes, air dermatomes), general surgical instruments, consumables and others.
End users - hospitals and clinics, academic and research and others.
Regional analysis of Global Skin graft Market:
US accounts for the maximum market share due to faster market uptake of new technology, favourable reimbursement scenario and greater expenditure on healthcare. Europe is the second largest market due to large disposable income and rising awareness which is led by France and Germany. Asia Pacific region is expected to generate fastest growth and is estimated to be led by China and India. However Japan has the largest market share in the region as of 2016. Asia Pacific also has a
The Middle East & Africa market is led by the gulf nations particularly Saudi Arabia and UAE. The regions of Africa are expected to witness a moderate growth due to poor economic and political conditions and poor healthcare penetration.
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#Skin Graft Market#Skin Graft Market Size#Skin Graft Market Share#Skin Graft Market Growth#Skin Graft Market Trends#Skin Graft Market Outlook#Skin Graft Market Report#Skin Graft Market Analysis#Skin Graft Market Insights
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#skin graft market#skin graft market scope#skin graft market size#skin graft market share#skin graft market trend#skin graft market analysis
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Wound Healing Market Size, Share | Global Report 2030
A wound is a cut or opening. It might only be a minor abrasion or a paper-cut-sized incision. A fall, accident, or stress could result in a significant scratch, abrasion, or wound. A wound also includes a surgical incision produced by a medical professional while performing a surgery.
The most accessible organ in our body is the skin. As a result, it’s very simple to injure or damage it. The continuity of the body structure is lost when the epidermis is injured. Trauma, infection, or a pathological process like inflammation can all lead to this. A wound is made when the epidermis is injured or hurt. When this occurs, the body starts to heal itself right away. In order to re-establish tissue structure and repair the skin’s barrier function, it performs this.
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According to cognizance market research the wound healing market is valued at US$ 21.12 Billion and is anticipated to reach US$ 32.40 Billion by the end of 2030 with CAGR of 5.5% from 2023 to 2030.
The natural process by which the body replaces and repairs injured tissue is called wound healing. It comprises a complex mix of biological, molecular, and physical processes. It is a dynamic and complex process comprising of 4 stages: hemostasis, proliferative, inflammatory and maturation.
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Increasing Prevalence of Chronic Diseases, Diabetes and Surgical Cases to Boost Wound Healing Market
Due to the rise in surgical procedures and the frequency of chronic illnesses worldwide, there is a growing demand for wound healing products. One of the main drivers of market expansion is the rising prevalence of diabetes brought on by the widespread uptake of a sedentary lifestyle.
Diabetes prevents wounds from recovering properly. The American Diabetes Association estimates that 34.2 million Americans, or 10.5% of the country’s population, had diabetes in 2018.The prevalence of diabetes has considerably increased over the past few decades, and both acute and chronic wound instances have significantly increased as well. Surgery has grown as a result of an increase in the elderly population. The complexity of wounds has grown due to an increase in weight and other health issues, particularly for infections, ulcerations, and other conditions.
The wound healing market is anticipated to grow due to an increase in traumatic injuries globally. For instance, according to the WHO, traffic-related accidents are thought to be the cause of 22,941 deaths in Thailand each year, or about 33% of all fatalities there. One of the main drivers of the wound healing market is the rising prevalence of burn injury instances worldwide. It is resulting in the production of brand-new, cutting-edge burn treatment goods like biologics, grafts, and bandages.
North America to Spearhead the Wound Healing Market
North America is the fastest-growing segment in the wound healing market due to several factors, including:
Increasing number of traffic accidents: There has been a notable rise in accidents in North America over the past few years. People who sustain accidents require first aid care right away. The role of wound healing methods becomes crucial in the case of severe accidents. Therefore, the need for cutting-edge wound healing services and goods is growing as a result of these variables. These elements support market demand opportunities for wound healing.
Increasing Investment in Healthcare infrastructure and facilities: Governments and private organizations in North America are investing heavily in healthcare infrastructure and research and development. This investment is driving innovation and the development of new products for a range of wound healing.
High number of geriatric and diabetic population: The demand for enhanced wound healing methods is expected to increase as a result of the increasing number of diabetic patients and the ageing population in North America. Their weakened immune systems are one of the main factors contributing to the rise in demand for mending methods among this patient population. This circumstance creates market expansion possibilities for wound healing.
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Competitive Insights
Companies operating in the wound healing market have adopted several growth strategies to expand their market share and increase their revenue. Some of the key players operating in wound healing industry are IonMed Ltd.; Smith & Nephew plc; Acelity L.P. Inc.; Mölnlycke Health Care AB; Ethicon, Inc.; Convatec Group Plc; Baxter; Coloplast Group; PAUL HARTMANN AG; MiMedx.; DeRoyal; Organogenesis Inc.; ACell Inc.; Talley Group Ltd,; Medtronic plc; 3M; Integra LifeSciences Holding Corporation; Lohmann & Rauscher International GmbH & Co. KG; Kerecis; Medela AG. DBMR.
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Skin Graft Market Share, Growth Factors, Competitive Landscape and Forecast to 2030
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