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Immersion dans une entreprise de textile Alsacienne : Emmanuel Lang
Visite chez Emmanuel Lang à Hirsingue dans le sud de l'Alsace. Cette entreprise multiséculaire (créé en 1856) est spécialisée dans la fabrication de tissus dit tombé métier. Cela signifie que les opérations d'ennoblissement (dernières étapes de finitions) sont réalisés par d'autres entreprises tel que ETC, elle aussi Alsacienne.
Processus
Les fils. Tout comment par là. Ils proviennent notamment d'Italie ou encore du Nord de la France. 
Puis, plusieurs étapes sont alors réalisées :
le bobinage : création de bobines de fils avec un métrage précis
l'ourdissage : les fils sont vidés de leur bobine et enroulés autour d'un rouleau que l'on appelle ensouple. Ils forment alors la chaîne du tissus (fils verticaux)
l’encollage : de la colle est appliquée sur ces fils de chaines pour les consolider avant l'opération de tissage
et le tissage : un fil de trame (horizontal) passe entre les fils de chaîne (vertiaux)
Particularités
L'entreprise est connue pour ses tissus piqués (tissu assez moelleux) ou encore en seersucker, une matière très agréable l'été car elle sèche rapidement, est assez aérée, ne colle pas trop au corps et n'a pas besoin de beaucoup de repassage.
L'entreprise peut également s'appuyer sur ses archives pour créer de nouveaux tissus. Et elles ne manquent pas, puisque les plus anciennes datent de 1885.
  Distribution
Emmanuel Lang propose également sa propre ligne de chemises via la boutique Matières Française à Colmar.
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bharatiyamedia-blog · 5 years
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Genetic research of the causes of extra liver iron could result in higher therapy
http://tinyurl.com/yxj86uwa Credit score: CC0 Public Area Excessive ranges of iron within the liver are linked to quite a lot of severe well being situations together with most cancers, diabetes, hypertension and cardiovascular in addition to liver illness. However measuring liver iron is troublesome and till just lately may solely be carried out by means of an invasive biopsy. Now researchers from College of Exeter, U.Okay., along with colleagues from the College of Westminster,London, UK, Lund College, Sweden and Perspectum Diagnostics, Owford, UK, have proven that genes regulating iron metabolism within the physique are chargeable for extra liver iron. These genes are the driving explanation for excessive ranges of iron within the liver in populations of European, particularly Celtic, ancestry, and counsel that that is more than likely a systemic and never organ-related downside. This discovering can level the best way to easy methods for decreasing the surplus. The analysis is introduced on the annual convention of the European Society of Human Genetics in the present day (Monday). Dr. Hanieh Yaghootkar and colleagues carried out genome-wide affiliation research on liver iron content material, measured by way of magnetic resonance imaging (MRI), in 8200 volunteers who had supplied organic samples to the U.Okay. Biobank. Genome-wide association studies work by scanning markers throughout the whole units of DNA of huge numbers of individuals to be able to discover genetic variants related to a selected situation. They discovered three unbiased genetic variants related to larger liver iron and concerned within the manufacturing of hepcidin, a protein that regulates the entry of iron into the blood. The outcomes had been validated in 1500 people whose information had been collected within the pan-European Diabetes Analysis on Affected person Stratification (DIRECT) Consortium. “That is the primary time such a research has been carried out in an unselected, massive inhabitants,” says Dr. Yaghootkar. The investigators used a genetic method to discover the causal hyperlink between larger waist-to-hip ratio and elevated liver iron content material. This supplied genetic proof that larger central (stomach) weight problems was related to elevated liver iron ranges. “There are animal research that point out that fats cells set off macrophages, a kind of white blood cell, to trigger irritation, and that this in flip results in faulty iron dealing with within the liver. We have to analysis this affiliation additional, however it’s a believable clarification of the phenomenon,” says Dr. Yaghootkar. The truth that the mechanisms inflicting elevated liver iron had been generalized and never organ-specific implies that excessive iron ranges most likely happen in different organs too, together with the mind. The researchers discovered an affiliation between extra iron and plenty of different issues, together with neuropsychiatric situations. As a result of the scientific manifestations of elevated iron ranges are so numerous, a multi-specialty method will probably be wanted to evaluate and consider new therapies, together with treating sufferers with hepcidin to cut back iron accumulation. MRI is continuous for 100,000 people within the Biobank research. “This can permit us to search out many extra genetic components related to this trait. We’re additionally thinking about performing such research in different ethnicities, since our present outcomes are solely legitimate for folks of European ancestry,” Dr. Yaghootar will conclude. Chair of the ESHG convention, Professor Joris Veltman, Director of the Institute of Genetic Medication at Newcastle College, Newcastle upon Tyne, U.Okay., mentioned: “Iron overload is dangerous for the physique and must be tightly regulated. The genetic research introduced on the ESHG in the present day reveals a key function for genes regulating iron metabolism, and likewise revealed a hyperlink between sure forms of weight problems and iron overload.” New treatment for iron overload on trial Extra info: Summary no: C. 21.5 Genome-wide affiliation research of MRI liver iron content material in 9,800 people yields new insights into its hyperlink with hepatic and extrahepatic ailments Offered by European Society of Human Genetics Quotation: Genetic research of the causes of extra liver iron could result in higher therapy (2019, June 17) retrieved 17 June 2019 from https://medicalxpress.com/information/2019-06-genetic-excess-liver-iron-treatment.html This doc is topic to copyright. Aside from any truthful dealing for the aim of personal research or analysis, no half could also be reproduced with out the written permission. The content material is supplied for info functions solely. Source link
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english-idylls · 8 years
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Oxford Canal near Lower Heyford by Howard Somerville.
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bharatiyamedia-blog · 5 years
Text
Genetic research of the causes of extra liver iron might result in higher remedy
http://tinyurl.com/y3audlgc Excessive ranges of iron within the liver are linked to a lot of severe well being circumstances together with most cancers, diabetes, hypertension and cardiovascular in addition to liver illness. However measuring liver iron is troublesome and till just lately may solely be carried out by an invasive biopsy. Now researchers from College of Exeter, UK, along with colleagues from the College of Westminster,London, UK, Lund College, Sweden and Perspectum Diagnostics, Owford, UK, have proven that genes regulating iron metabolism within the physique are liable for extra liver iron. These genes are the driving reason for excessive ranges of iron within the liver in populations of European, particularly Celtic, ancestry, and recommend that that is probably a systemic and never organ-related drawback. This discovering can level the best way to easy methods for decreasing the surplus. The analysis is offered on the annual convention of the European Society of Human Genetics at this time (Monday). Dr Hanieh Yaghootkar and colleagues carried out genome-wide affiliation research on liver iron content material, measured through magnetic resonance imaging (MRI), in 8200 volunteers who had supplied organic samples to the UK Biobank. Genome-wide affiliation research work by scanning markers throughout the entire units of DNA of huge numbers of individuals in an effort to discover genetic variants related to a specific situation. They discovered three impartial genetic variants related to larger liver iron and concerned within the manufacturing of hepcidin, a protein that regulates the entry of iron into the blood. The outcomes have been validated in 1500 people whose information had been collected within the pan-European Diabetes Analysis on Affected person Stratification (DIRECT) Consortium. «That is the primary time such a research has been carried out in an unselected, massive inhabitants,» says Dr Yaghootkar. The investigators used a genetic method to discover the causal hyperlink between larger waist-to-hip ratio and elevated liver iron content material. This supplied genetic proof that larger central (stomach) weight problems was related to elevated liver iron ranges. « There are animal research that point out that fats cells set off macrophages, a sort of white blood cell, to trigger irritation, and that this in flip results in faulty iron dealing with within the liver. We have to analysis this affiliation additional, however it’s a believable clarification of the phenomenon, » says Dr Yaghootkar. The truth that the mechanisms inflicting elevated liver iron have been generalised and never organ-specific implies that excessive iron ranges in all probability happen in different organs too, together with the mind. The researchers discovered an affiliation between extra iron and lots of different problems, together with neuropsychiatric circumstances. As a result of the medical manifestations of elevated iron ranges are so various, a multi-specialty method might be wanted to evaluate and consider new therapies, together with treating sufferers with hepcidin to cut back iron accumulation. MRI is continuous for 100,000 people within the Biobank research. « This can permit us to search out many extra genetic elements related to this trait. We’re additionally enthusiastic about performing such research in different ethnicities, since our present outcomes are solely legitimate for folks of European ancestry, » Dr Yaghootar will conclude. Chair of the ESHG convention, Professor Joris Veltman, Director of the Institute of Genetic Medication at Newcastle College, Newcastle upon Tyne, UK, mentioned: “Iron overload is dangerous for the physique and must be tightly regulated. The genetic research offered on the ESHG at this time reveals a key position for genes regulating iron metabolism, and likewise revealed a hyperlink between sure forms of weight problems and iron overload.” ### Summary no: C. 21.5 Genome-wide affiliation research of MRI liver iron content material in 9,800 people yields new insights into its hyperlink with hepatic and extrahepatic illnesses Disclaimer: AAAS and EurekAlert! aren’t liable for the accuracy of reports releases posted to EurekAlert! by contributing establishments or for using any info by the EurekAlert system. Source link
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