#watanabe yoshimi

[trashexplorer]

BLCD Review: Unmei no Tsugai ga Omae da Nante

Title: Unmei no Tsugai ga Omae da Nante (運命の番がお前だなんて)

Author/Artist: Haruta

Release Date: 2021/06/25

Cast: 

Okitsu Kazuyuki x Masuda Toshiki

Taito Ban

Tsuchida Reiou

Kobayashi Kousuke

Matsuura Yoshiyuki

Tanaka Tomomi

Watanabe Yoshimi

Synopsis: Free-spirited omega Shishikura and straight-laced alpha Kotani have disliked each other since middle school, so neither are pleased to learn they will both be working at the same company. Shishikura is even less thrilled when he discovers that he and Kotani are a fated pair! The two men take verbal swipes at each other every chance they get, yet still wind up in bed together again and again. Both chalk it up to biology and refuse to admit that deeper feelings might be involved, and Shishikura begins looking into other potential marriage partners. Will this tsundere couple ever get their act together, or will destiny be derailed by their own stubbornness?

Review Proper

Finally, the thing I mistook for Yukyuu Omega is here. *exhale*

If y’all know me, you’ll know that I absolutely abhor omegaverse (you can thank Kurui Naku Ban Beta, Sayonara Alpha, and Erito for that). Literally everything you could do in an abo has already been done. I don’t see a point in making more of these. Mangakas: Okay, let’s do domsub instead But hey, am I not a Okitsu whore? No. Anyway, even though I was excited about listening to this, I knew I was going to hate Kotani because he was an asshole. 

There’s only one thing worse than an abo.

AN ABO WITH AN ASSHOLE CHARACTER.

But, in spite of myself, I actually enjoyed this. 

I’m having a moral crisis, help.

JK. Unmei no Tsugai doesn’t sell itself as a serious plot, so it shouldn’t be taken seriously either. Unlike our deep try-hards. I mean, it’s your pretty run-of-the-mill dumbass gets an excuse to fuck the asshole, falls in love with him, the asshole becomes more of an asshole, the dumbass drags a third party to make him jealous, the asshole becomes more of an asshole, poor third party gets led on and dumped, and the dumbass and asshole finally gets together without the asshole even apologizing, medetashi, medetashi. But the way that Haruta wrote and movic set it all up was fantastic. 

Now this is how you do comedy. I initially had some doubts ‘cause the narration in the first track was kind of strange lmao. It went from medieval style to traditional Japanese and it was narrated by someone who sounded like a news broadcaster wth. Is this a densetsu??? The CD later turned out to be a whole vocal flex for Massuu and Okitsu ‘cause goddamn. 

Massuu, for starters, used a tone slightly above his Hirokuni but slightly smoother. I haven’t read the manga before, so I wasn’t sure how things were going to go, so I was very surprised that he pulled his shounen (aka his Kirishima) voice later! I loved it. His changes were dynamic, chaotic, and very fitting for Shishikura. AND! AND! JESUS CHRIST HIS SEXAY MONOLOGUES!!! HELLO??? WAS HE PAID EXTRA??? Y’ALL GOTTA HEAR ALL THE BEDROOM SUBJUGATIONS!!! I didn’t know he had that in him tbh. I was just blown away. He has never bottomed this chaotically before, if I recall correctly. It’s evident that he had a lot of fun recording this (as did Okitsu as per the cast talk) and I love that! It makes me wish this had a second volume so we could hear more of this kind of Massuu.

Onto Okitsu,

Y’all already know what I’m gonna say. 

Is my bias over Okitsu making me like this? Who knows? But it’s undeniable that my man has, once again, slayed this role. I won’t talk about his perfect performance much ‘cause I’ve already run out of praises years ago, so just know that if you’re not an Okitsu bitch by now, you’re really missing out lmao.

ALSO

I CAN’T BELIEVE THAT WE’VE WITNESSED OKITSU PLAY TWO BETAS, A PRETEND OMEGA, AND NOW FINALLY AN ALPHA!!! We don’t count the disrespect that was Shounen no Kyoukai

-Chesk, 25, hates abos but will listen if Okitsu’s in it

Anywho, these two also had great chemistry with each other. They’re more or less in sync during their mattress mambos, so I really wasn’t spazzing out during Smoky Nectar. I was thinking maybe I was asking for too much. 😂 Idk what to feel, knowing that this is Fatgum x Kirishima

In conclusion, get this. Get this if you’re a fan of the series and abo in general. And if you dislike abo like me, this still is worth getting if you’re an Okitsu/Massuu stan. If you want to see just what makes voice actors good, you’ll be in the right place. As for those who want to read the manga along with the BLCD, it is doable, but bear in mind that there is added and cut dialogue. I only have the magazine releases, and I’ve noticed that the narrations are rearranged, so do try buying the tank if you can (reading the Chrima release with it is doable too tho). Gosh, I really wish this wasn’t an abo lmao. Anyway, I’m afraid there aren’t a lot of gag abos like this out there, so I wouldn’t be able to recommend anything similar. Go Kashikomarimashita: Destiny and Re:birth for more Okitsu tho

#blcd reviews #blcd 2021 reviews #unmei no tsugai ga omae da nante #haruta #movic #okitsu kazuyuki #masuda toshiki #taito #kobayashi kousuke #tsuchida reiou #matsuura yoshiyuki #tanaka tomomi #watanabe yoshimi

[catatonic-indifference]

#music #ost #basiscape #sakimoto hitoshi #kaneda mitsuhiro #kudo yoshimi #watanabe rikako #kikuchi yukinori #13 sentinels: aegis rim

[todropscience]

RESEARCHERS UNCOVER A NEW SPECIES OF BEAKED WHALE FROM THE COAST OF JAPAN

A new beaked whale species named Black-billed whale (Berardius minimus), which has been recognized by Hokkaido whalers for long has been confirmed. Known locally as Kurotsuchikujira 黒ツチクジラ, which means black Baird's beaked whale, this species differs from other beaked whales by having a substantially smaller body size of physically mature individuals, proportionately shorter beak, and darker body colour.

- Possible Black-billed whale Berardius minimus sighted in Nemuro strait. Note the short beak, dark body colour, and sparse linear scars (photo taken by Hal Sato on 21 May 2009).

Beaked whales prefer deep ocean waters and have a long diving capacity, making them hard to see and inadequately understood. Researchers still don't know how mature Berardius minimus female look like, as no female where found yet. The diet of this species is unclear.  

Main image: Illustrations of Black-billed whale and Baird's beaked whale. In general appearance, Black-billed whale resembles a small Baird's beaked whale with a proportionately shorter beak and more spindle-shaped body  The black bars show 1 m, drawn by Yoshimi Watanabe, National Museum of Nature and Science.

Reference: Tadasu et al., 2019. Description of A New Species of Beaked Whale (Berardius) found in the North Pacific. Scientific Reports. 

#Berardius minimus #new species #northwest pacific #science #marine biology #ziphidae #berardius #cetacean #beaked whale #Black-billed Whale

[landofanimes]

SHINING MOON TOKYO

As previously announced, the Sailor Moon show restaurant that opens up on August 15 in Azabu-Juuban (Tokyo, Japan) will feature an exclusive stage show while guests dine Sailor Moon themed food! 

Check out the full cast:

Sailor Moon/Usagi Tsukino: Reona Samejima, Shina Tanaka Sailor Mercury/Ami Mizuno: Cocona*, Yui Hayashi Sailor Mars/Rei Hino: Mika Taguchi,  Kyoko Ninomiya* Sailor Jupiter/Makoto Kino: Mayuka Ida, Ayaka Ozaki Sailor Venus/Minako Aino: Nanae Abe, Yu Nakanishi*  Tuxedo Mask/Mamoru Chiba: Hikari Aoba, Sufa

Ensemble: Erina Arasawa, Yurika Uchida, Misaki Okita, Suzuka Osawa, Miyuu Ohasi, Rinka Kurio, Kurea Saito, Yukari Shiihara, Mana Shinohara, Chiemi Doi, Yoshimi Hidano, Ayano Watanabe

*Trivia: Three senshi actresses reprise their roles from The Super Live: Cocona (Cast ❤, Team Paris), Kyoko (Cast  ◆) and Yu (Cast  ◆, Team America)

#sailor moon #sera myu #shining moon tokyo #inner senshi #tuxedo mask #sailor venus #sailor jupiter #sailor mercury #sailor mars #smt cast #the super live cast #bssm #also omg yet another set of stage outfit style XD

[goalhofer]

2019 Chunichi Ryu Roster

Pitchers

#11 Ogasawara Shinnosuke (Fujisawa, Japan)

#13 Hashimoto Yuki (Takahama, Japan)

#16 Matayoshi Katsuki (Urasoe, Japan)

#17 Yanagi Yuya (Miyakonojo, Japan)

#19 Yoshimi Kazuki (Kyoto, Japan)

#21 Okada Toshiya (Hidaka, Japan)

#22 Yudai Ono (Kyoto, Japan)

#28 Umetsu Kodai (Fukushima, Japan)

#29 Yamai Daisuke (Osaka, Japan)

#30 Achira Takuma (Osaka, Japan)

#34 Fuku Hiroto (Kobe, Japan)

#36 Okano Yuichiro (Ishinomaki, Japan)

#43 Mitsuma Takuya (Takasaki, Japan)

#53 Luis Gonzalez (Valverde Mao, Dominican Republic)

#54 Fujishima Kento (Toyohashi, Japan)

#59 Yamamoto Takumi (Takarazuka, Japan)

#70 Enny Romero (Santo Domingo, Dominican Republic)

#97 Raidel Martinez (Pinar Del Rio, Cuba)

#98 Kinoshita Yusuke (Osaka, Japan)

Catchers

#35 Kinoshita Takuya (Kochi, Japan)

#44 Gunji Yuya (Ichihara, Japan)

#52 Kato Takuma (Matsusaka, Japan)

#68 Katsura Iori (Osaka, Japan)

Infielders

#1 Kyoda Yota (Nomi, Japan)

#3 Takahasi Shuhei (Fujisawa, Japan)

#5 Abe Toshiki (Ichinoseki, Japan)

#7 Neo Akira (Hida, Japan)

#9 Shun Ishikawa (Kusatsu, Japan)

#37 Mitsumata Taiki (Katsushika, Japan)

#48 Mizowaki Hayato (Tamana, Japan)

#55 Fukuda Nobumasa (Yokohama, Japan)

#66 Dayan Viciedo (Remedios, Cuba)

Outfielders

#26 Iryo Masataka (Yotsukaido, Japan)

#31 Watanabe Masaru (Yokohama, Japan)

#45 Moises Sierra (Santo Domingo, Dominican Republic)

#49 Ito Kosuke (Gamagori, Japan)

#56 Takeda Kengo (Chikugo, Japan)

Coaches

Manager Yoda Tsuyoshi (Kimitsu, Japan)

Bench coach Ito Tsutomu (Kumamoto, Japan)

Hitting coach Alonzo Powell (San Francisco, California)

Assistant hitting coach Murakami Takayuki (Omuta, Japan)

Assistant hitting coach Kurihara Kenta (Tendo, Japan)

Assistant hitting coach Nakamura Takeshi (Kyoto, Japan)

Pitching coach Awano Hideyuki (Yokohama, Japan)

Assistant pitching coach Akahori Motoyuki (Shizuoka, Japan)

Infield coach Masahiro Araki (Kikuchi, Japan)

Outfield coach Hidenori Kuramoto (Hashima, Japan)

#Sports #Baseball #Japan #Celebrities #Dominican Republic

[chiyamabunny]

Miyano Mamoru LINE Blog: 2019/6/1 (Eng. Translation)

「LUPIN THE ⅢRD 峰不二子の嘘」&「シブヤノオト」&「M-ON! SPECIAL」 「LUPIN THE IIIRD: Fujiko Mine's Lie」&「Shibuya Note」&「M-ON! SPECIAL」 2019/6/1 14:36

今日は、

映画「LUPIN THE ⅢRD 峰不二子の嘘」の、 The Movie "LUPIN THE IIIRD: Fujiko Mine's Lie" it's,

公開記念舞台挨拶が行われまして、 Public Commemorative Stage Greetings were held,

ビンカム役のわたくし宮野真守は、 Miyano Mamoru plays the role of Binkam,

峰不二子役の沢城みゆきさん、小池健監督、そして浄園祐プロデューサーと、 Fujiko Mine's actor is Sawashiro Miyuki-san, Director Koike Takeshi, and Producer Kiyozono Yu,

登壇してまいりました! We were on stage!

久しぶりに、沢城とステージに立って、 It's been a while, since I've stood on a stage with Sawashiro,

楽しくお話しできて嬉しかったなぁ☆ I was happy to have a fun talkk☆

今回の作品の、不二子… This time's work, Fujiko…

沢城だからこその、「不二子」です!!!!!!!! It's because it's Sawashiro that it is "Fujiko"!!!!!!!!

素晴らしすぎる…!!! Way too wonderful…!!!

みなさま、是非劇場でご覧ください☆ Everyone, please watch it in theaters by all means☆

そして、本日は、 And, today,

わたくしがゲスト出演させていただく、 I will be making a guest appearance,

NHK総合「シブヤノオト」が、 NHK General "Shibuya Note" is,

オンエアされます!! On air!!

新曲「アンコール」をパフォーマンスします!! I will perform my new song "Encore"!!

MCの徳井義実さんと渡辺直美さんとも、楽しくトークさせていただきました☆ With the MC Tokui Yoshimi-san and Watanabe Naomi-san, we had a fun talk☆

テレビの前で、チェックしてみてくださいね♪ In front of the TV, please check it out, kay♪

NHK総合「シブヤノオト」 NHK General "Shibuya Note"

6月1日（土）24:05～ June 1st (Sat.) 24:05～

オンエアです!! On air!!

よろしくお願いします!! yoroshiku onegaishimasu!!

そしてそして、さらに! And and, furthermore!

MUSIC ON! TVにて、 On MUSIC ON! TV,

「M-ON! SPECIAL 「宮野真守」 ～アンコール～」 "M-ON! SPECIAL "Miyano Mamoru" ～Encore～"

こちらも、 This as well,

本日放送されます!! Will be broadcast today!!

17thシングル 「アンコール」の発売を記念した特別番組なのです☆ It's a special program to commemorate the released of my 17th Single "Encore"☆

宮野への「つかの間の癒し」を、用意してくださったので、 Since a "Moment of Healing" had been prepared for Miyano,

番組内で、宮野がどのように癒やされてるのか、 Within the show, how Miyano is healed,

是非お確かめください☆ Please see for yourself☆

MUSIC ON! TV「M-ON! SPECIAL 「宮野真守」 ～アンコール～」は、 MUSIC ON! TV "M-ON! SPECIAL "Miyano Mamoru" ～Encore～",

6月1日（土）22:00～23:00 June 1st (Sat.) 22:00～23:00

オンエアです!! On air!!

お楽しみに♪ Look forwards♪

#miyano mamoru #seiyuu #mamo blog #sawashiro miyuki #lupin the third #shibuya note #encore

[crazykacey]

okay I know that everyone and their mother has posted about this I’m gonna do it too lol

Okay so Shining Moon Tokyo cast was released OMG YAZ and here are tha cast AND their social medias!!(and yes it’s a double cast but no teams or such have been announced)

Reona Samejima as Sailor Moon Twitter | Instagram

Shina Tanaka as Sailor Moon Twitter

Cocona as Sailor Mercury (also performed as Sailor Mercury in the Super Live In Team Heart and Team Paris!) Twitter | Instagram

Yui Hayashi as Sailor Mercury Twitter | Blog

Mika Taguchi as Sailor Mars Twitter

Kyoko Ninomiya as Sailor Mars (also performed as Sailor Mars in the Super Live in Team Diamond and Team Birthday) Twitter | Instagram | Blog

Mayuka Ida as Sailor Jupiter (also the understudy of Sailor Mars in NogiMyu) Twitter | Instagram

Ayaka Ozaki as Sailor Jupiter Twitter | Blog

Nanae Abe as Sailor Venus (nothing found :( )

Yuu Nakanishi as Sailor Venus (also performed as Sailor Venus in the Super Live in Team Diamond, Team America and Team Birthday) Twitter

Hikari Aoba as Tuxedo Mask Twitter | Instagram

Sufa as Tuxedo Mask Twitter

and now for the Ensemble cast and oh boy I’m gonna be here for a long time cause there is A LOT

Erina Arasawa, Yurika Uchida (Twitter), Misaki Ookita, Suzuka Oosawa (also Ensemble in Super Live Teams Heart/Music Note/Paris Twitter | Instagram), Miyuu Oohashi (also Ensemble in Super Live Teams Heart/Music Note/Paris Twitter | Instagram), Rinka Kurio (Twitter | Instagram), Kurea Saitou (Twitter | Instagram), Yukari Shiihara (also Ensemble In Le Mouvement Final Twitter | Instagram) Mana Shinohara (Twitter), Chiemi Doi (also Ensemble in Amour Eternal Twitter), Yoshimi Hidano (also Ensemble in Amour Eternal and Le Mouvement Final Twitter | Instagram) & Ayano Watanabe

#sailor moon #sera myu #shining moon tokyo #super live #sailor moon the super live #sailor moon super live #reona samejima #samejima reona #tanaka shina #shina tanaka #cocona #yui hayashi #hayashi yui #mika taguchi #taguchi mika #kyoko ninomiya #ninomiya kyoko #mayuka ida #ida mayuka #ayaka ozaki #ozaki ayaka #nanae abe #abe nanae #yuu nakanishi #nakanishi yuu #yu nakanishi #nakanishi yu #hikari aoba #aoba hikari #sufa

[zblog11]

Cast for Shining Moon Tokyo

Sailor Moon (Double Cast )

Reona Samejima(https://twitter.com/samejimareona)

Shina Takana(https://twitter.com/chi_na524)

Sailor Mercury(Double Cast)

Cocona (from Super Live) (https://twitter.com/cocona_obp)

Yui Hayashi (I think this is her https://twitter.com/yuiyui199603)

Sailor Mars(Double Cast)

Mika Taguchi (https://twitter.com/ohagidaisuki226)

Kyoka Ninomiya (from Super Live) (https://twitter.com/ninomiya_kyoko)

Sailor Jupiter (Double Cast)

Mayuka Ida (Sailor Mars NogiMyu understudy) (https://twitter.com/id_mayuka)

Ayaka Ozaki(https://twitter.com/reikaya66)

Sailor Venus(Double Cast)

Nanae Abe (found no social media for her)

Yu Nakanishi(From Super Live) (https://twitter.com/N_ttay)

Tuxedo Mask(Double Cast)

Hikari Aoba(https://twitter.com/0323_aoba)

Sufa(no social media found)

Ensemble:

Erina Arasawa, Yurika Uchida (https://twitter.com/517_yurika),Misaki Okita,Suzuka Osawa(was in super live)(https://twitter.com/himegami_suzuka),Miyuu Ohashi(was in super live) (https://twitter.com/Miyuu_ohashi),Rinka Kurio(https://twitter.com/himegami_rinka),Kurea Saito(https://twitter.com/_kurea_828),Yukari Shiihara(https://twitter.com/yukarishiihara),Mana Shinohara(https://twitter.com/Smana0503),Chiemi Doi(https://twitter.com/chiemidoi),Yoshimi Hidano(she’s been in seramyu before I believe) (https://twitter.com/yochimimm),Ayano Watanabe

#sera myu #seramyu #sailor moon #sailor moon musicals #sailor moon musical #bishoujo senshi sailor moon #shiningmoontokyo #usagi tsukino #tsukino usagi #sailor mercury #ami mizuno #mizuno ami #sailor mars #rei hino #hino rei #sailor jupiter #makoto kino #kino makoto #sailor venus #aino minako #minako aino #tuxedo kamen #tuxedo mask #mamoru chiba #chiba mamoru

[materialsscienceandengineering]

Stress of stretching solids: 3D image shows how particles distribute in metals

From the pots and pans on the stove to the wires suspending bridges, metal composites need to account for a variety of strength, malleability, and durability to meet human need. Now, researchers from the Nagoya Institute of Technology (NITech) in Japan have applied three-dimensional crystallography to visualize how individual particles shape up the composites -- and how they might be manipulated to make better versions of themselves

"Strength of the composite is controlled by size, spatial distribution, and three-dimensional shape of the particles," said Dr. Hisashi Sato, an associate professor in the Graduate School of Engineering and in the Frontier Research Institute for Materials Science. He collaborated on this research with Prof. Yoshimi Watanabe.

In making the composites, such as drawing out metal alloys to make suspension wire for bridges, the materials are pressed and stressed to break apart the particles. The particles are then drawn out into a thinner rearrangement, but they must be carefully controlled to avoid losing strength or becoming brittle. This process, called Equal Channel Angular Pressing (ECAP), is referred to as "deforming" the particles of the composite from their original state.

Read more.

#Materials Science #Science #Materials Characterization #Metals #Particles #Crystallography #Crystals #Composites #Nagoya Institute of Technology #Alloys #Deformation mechanisms

[precuresplashstar]

not kidding about that last post even a ltitle bit, good lord

tanaka’s board is phenomenal, of course, but in the case of an episode like this, id be doing both it and everybody reading it a disservice by not talking about everybody else involved in making it as special as it was. koudai watanabe’s bold figures, loose expressions, and impeccable sense of style are a pretty big part of what elevated this from “another fantastic tanaka episode” to “unquestionably the best single episode of winter 2018″, and thats not touching on the actual animation work watanabe did for the episode, displaying his versatility through the delightful basketball scene and the episode’s breathtaking action climax

and even beyond watanabe, its important to talk about the all-star lineup of young animators working under his supervision:

shunsuke okubo, a previously almost completely unheard of toei animator with only one prior key animation credit to his name handled a lot of incredibly delicate work without missing a beat; homare’s reserved body language and expressions sell everything the episode says to us about her; emotional beats that land with such force because they are conveyed flawlessly through the visuals

takumi yamamoto, who worked with watanabe on all of his tiger mask w episodes and returns here with style; handling a significant portion of the cheery, smear filled opening scene as well as the cuts that expertly establish the scale of the fight at the end

and of course, fast rising industry star keisuke “masami” “yoshimi” “yoshiyuki” mori (perhaps best known as soty), whose extremely capable hand makes the show into both a delightfully expressive cartoon and gives credence to the weightiest moments of its drama

i dont actually have a good way to wrap up this post. uhhh please watch precure

#hugtto precure #episode writeups

[fdxjapan2020]

Day 23 (2) - Toyama Glass Art Museum exhibition: “Microcosmos, experimenting with new kinds of interaction”

The modern building designed by Kuma Kengo houses both the Toyama Glass Art Museum and the city’s public library, and it has 6 levels.

The permanent exhibitions are spread on two floors, and showcases glass work by Japanese and international glass artists. The Microcosmos temporary exhibition I was privileged to see featured work by contemporary Japanese artists, namely: Machiko Ito, Mafune Gonjo,Yoshimi Taniguchi, Runa Kosogawa, Natsuki Katsugawa, Makiko Inoya, and Chiemi Watanabe. All work on display was deeply impressive.

😴 Hotel Route-Inn Takaoka Ekimae, Takaoka, Toyama Prefecture

[rz-jocelyn]

And the cuteness of Kashuu Kiyomitsu (Sato Ryuji), Yamatonokami Yasusada (Torigoe Yuki), Izuminokami Kanesada (Arisawa Shoutarou) and Hachisuka Kotetsu (Takahashi Kensuke) from the Musical Touken Ranbu on NHK's "Shibuya Note" dated 02.07.2017 continues xDDDD

For BREAKERZ's part of the "Bucchake Damedashi Hansei-kai" segment, the audience message that the group received ended up being,

"If DAIGO-san, who is next to the Touken Danshi, is given a sword to hold, he seems like he could become like a Touken Danshi."

(For Team Shinsengumi with Hachisuka Kotetsu's part of the "Bucchake Damedashi Hansei-kai" segment, it can be found: HERE )

LOL! Which, leads to the cameraman trying to get a shot of DAIGO with the Touken Danshi as well as the hilariously adorable exchange below,

Tokui Yoshimi (MC): Could, could someone-

Watanabe Naomi (MC): Is it possible for someone lend him a sword?

Yamatonokami Yasusada: (tries to detach his sword) I can't detach it.

Watanabe Naomi (MC): Ah, you can't detach it?

Yamatonokami Yasusada: The sword, I can't detach it.

Kashuu Kiyomitsu: Because the swords are us.

Tokui Yoshimi (MC): Ah, I see.

Watanabe Naomi (MC): (to DAIGO) Ah, I'm so sorry. "Because the swords are us," they say-

DAIGO: It can't be helped.

Watanabe Naomi (MC): -it's a bit difficult [to lend you one].

*DYING*

Source: ( x )

#Musical Touken Ranbu #Touken Ranbu #Toumyu #Team Shinsengumi with Hachisuka Kotetsu #Shibuya Note #Shibuya no Oto #Tori is so cute trying to detach his sword #And Ryuji #Nice follow xDDD #He was so adorbs when he was explaining how the swords *were* them #And that little exchange between Okitagumi ♥ #KAWAII #Lyn Translates

[mariebenz]

Subtype of Schizophrenia Can Be Identified by Enzyme in Hair

Dr. Yoshikawa MedicalResearch.com Interview with: Dr.  Takeo Yoshikawa MD PhD RIKEN Center for Brain Science Japan MedicalResearch.com: What is the background for this study? What are the main findings? Currently available drugs for schizophrenia are the dopamine D2 receptor blockers. These compounds were serendipitously discovered over half-century ago. But about 30% of schizophrenia are resistant to the dopamine D2 receptor blockers. In spite of these conditions, pharmaceutical companies have abandoned the development of new drugs. This is because we do not know the principle of drug design. Therefore, we need to understand the molecular underpinning of as-yet unknown schizophrenia pathophysiology. Schizophrenia is diagnosed by only patients’ symptoms, not by biological examination. To search for biological underpinning for schizophrenia using experimental animals, we thought that we should examine an endophenotype (biological trait) relevant to schizophrenia. Then we targeted prepulse (PPI) performance. Here, dampened PPI is considered as a biological marker of psychiatric disorders, typically of schizophrenia. Importantly, PPI can be measured using the same behavioral paradigm between experimental animals and human. C57BL/6 (B6) inbred mouse shows higher (better) prepulse inhibition (PPI) performance, while C3H/He (C3H) inbred mouse shows lowered (worse ) PPI. We premised that C3H mouse is “schizophrenia-prone” and B6 is not. To know the molecular basis for differential PPI levels between the two inbred mouse strains, we performed comprehensive protein expression level analysis (proteomics analysis) using the brains of B6 and C3H mice. The expression levels of Mpst, a hydrogen sulfide (H2S)-producing enzyme, is elevated in C3H mouse compared to B6 mouse. Biochemical analysis also supported the elevated H2S production in C3H mouse compared to B6. The examination of human samples including postmortem brains, iPS-derived neural stem cells (neurospheres) and hair follicle cells, gave evidence that H2S production system is indeed up-regulated in schizophrenia. MedicalResearch.com: What are the main findings?  The previous studies regarding H2S have mainly focused on the beneficial role of H2S.  This is because organisms including mouse and human synthesize H2S endogenously.  Our study shows that H2S, when it is excessively synthesized, brings a detrimental effect in the brain. A functional consequence elicited by excess hydrogen sulfide production, or  how brain function is damaged by excess H2S production, is that excess H2S hampers  energy metabolism in the brain. An origin or cause that induces the hyper H2S production state is, epigenetic changes of genome DNA (DNA methylation), not inherent genetic (genome) polymorphisms (variants). Epigenetic changes can be elicited by subtle brain insults including viral infection of pregnant  mother. This scenario conforms to the so-called “neurodevelopmental hypothesis of schizophrenia genesis”, and our work deciphered one of concrete entities (mechanisms) underlying this hypothesis. Our study provides a quite novel paradigm for schizophrenia pathophysiology, and is hoped  to provide a new principle for drug design.  MedicalResearch.com: What should readers take away from your report? Response: Development of inhibitors of H2S-producing enzymes could be a boon for schizophrenia patients, in particular those who are not satisfied with current drugs. MedicalResearch.com: What recommendations do you have for future research as a result of this work? Response: We call the hyper production state of H2S as “sulfide stress”.By further delineating the precise mechanisms for “sulfide stress”, for example identifying the proteins that are susceptible to “sulfide stress”, we could know additional druggable targets for schizophrenia. MedicalResearch.com: Is there anything else you would like to add? Response: Schizophrenia is thought to be etiologically heterogeneous. Examination of MPST (a H2S synthesizing enzyme) expression in hair follicle cells could identify the subgroup of schizophrenia suffering from “sulfide stress”, or stratify schizophrenia.We need just around 10 hairs, and such collection should be noninvasive. This could lead to precision medicine of schizophrenia. Thank you very much again for your interest in our work.  Citation: Masayuki Ide, Tetsuo Ohnishi, Manabu Toyoshima, Shabeesh Balan, Motoko Maekawa, Chie Shimamoto‐Mitsuyama, Yoshimi Iwayama, Hisako Ohba, Akiko Watanabe, Takashi Ishii, Norihiro Shibuya, Yuka Kimura, Yasuko Hisano, Yui Murata, Tomonori Hara, Momo Morikawa, Kenji Hashimoto, Yayoi Nozaki, Tomoko Toyota, Yuina Wada, Yosuke Tanaka, Tadafumi Kato, Akinori Nishi, Shigeyoshi Fujisawa, Hideyuki Okano, Masanari Itokawa, Nobutaka Hirokawa, Yasuto Kunii, Akiyoshi Kakita, Hirooki Yabe, Kazuya Iwamoto, Kohji Meno, Takuya Katagiri, Brian Dean, Kazuhiko Uchida, Hideo Kimura, Takeo Yoshikawa. Excess hydrogen sulfide and polysulfides production underlies a schizophrenia pathophysiology. EMBO Molecular Medicine, 2019; DOI: 10.15252/emmm.201910695   The information on MedicalResearch.com is provided for educational purposes only, and is in no way intended to diagnose, cure, or treat any medical or other condition. Always seek the advice of your physician or other qualified health and ask your doctor any questions you may have regarding a medical condition. In addition to all other limitations and disclaimers in this agreement, service provider and its third party providers disclaim any liability or loss in connection with the content provided on this website.   Read the full article

#medicalresearch #RIKEN_CBS #schizophrenia

[milkbreadtoast]

im making a list of cool animators and it’s nowhere near complete but here’s the ones i have for now if ur curious

yoshimichi kameda (brushwork style, amazing action, dynamic, mp100 chara design)

yutaka nakamura (impact frames, yutapon cubes, so fluid, action GOD, BONES “top veteran”)

yoh yoshinari (beautiful effects, good at everything, trigger)

toshiyuki inoue (dennou coil, wolf children, ff)

takeshi honda (dennou coil)

kiyotaka oshiyama (dennou coil)

mitsuo iso (dennou coil)

yoshimi itazu (crying scene from dennou coil!)

takafumi hori (trigger, su)

james baxter

glen keane

masaaki yuasa (ping pong, super smooth)

(everyone who worked on flip flappers, mp100, opm, dennou coil, LWA is amazing)

atsuki shimizu (opm, ff, amazing fx)

shuhei handa (opm: genos’s beam, lwa)

yuuto kaneko (lwa, mp100: mob gets rekt)

Takumi sunakohara (bulbous, bubbly fx)

shouta mitsumiya (lwa!)

masaru sakamoto (lwa!!: shiny chariot)

Sushio (lwa, opm)

hayao miyazaki (director)

mamoru hosoda (director)

steve ahn (voltron, lok)

takashi kojima (ff)

keiichiro watanabe (ff, mp100, opm)

hakuyu go (ff, mp100: teru vs sakurai!!, bnha)

China (ff)

katsuhiko kitada (ff)

shun enokido (ff)

yuki igarashi (ff, mp100)

kazunori ozawa (ff)

yasunori miyazawa (cool morphy stuff, ping pong, ff)

satoshi shigeta (ff: mecha)

keisuke kojima (ff)

ryu nakayama (ff, also sao fx)

yukina kosaka (ff)

toya oshima (ff)

naoya wada (ff)

chikashi kubota (ff)

hironori tanaka (ff)

akira hamaguchi (ff)

kei suezawa (ff)

tadaka mori (ff)

hisaya kuwabara (ff)

kazuto arai (ff, mp100: teru vs miyagawa!,mob vs dimple, bnha)

yumi ikeda(ff: that one transformation scene >_> )

isuta meister (ff)

Miso (ff, mp100)

ran kamezawa (ff)

tatsuya satou (amazing kyoani)

taichi ishidate (kyoani)

sara moroyuki(mp100: ep 4)

miyo sato (mp100: paint on glass)

Takashi mitani (mp100: teru vs terada)

Shin ogasawara (mp100: mob vs teru)

toshiyuki sato (mp100: this is my hostility, opm: cool genos blasts )

takuji miyamoto (mp100: that one bit w/ 1000% reigen)

Seung ho park (yoi opening)

bahi JD (webgen, opm)

Shinya takahashi (konosuba)

Megumi kouno (shelter,opm)

Norio matsumoto (naruto)

Se jun kim (mecha, opm: “beams”)

Ryuta yanagi (SAO fx)

Naoki kobayashi (naruto)

Rapparu (webgen?, distinct “messy looking” style, wobbly lines, cool fx)

andrewanims/andoru (stick figure animator, has a lot of promise!)

Noriyuki kitanohara (nichijou chase scene)

Gosei oda (opm, cool smears)

Hiroyuki imaishi (trigger, awesome squash + stretch, dynamic)

Arifumi imai (opm: saitama vs genos!)

Toshi sada (opm: ep3)

Shingo abe (opm: ep3)

Takashi tomioka (opm: sea king)

Tomohiro Shinoda (opm: sonic, boros)

Norifumi Kugai (opm: saitama dream)

#fluffprattle #ignore the comments #ijust put some stuff to help me remember a little #edit: added some more #note: if u want to see what they've done look them up on sakugabooru!!! #or google their names and ''mad'' on youtube #*i mean search lol #still dont know what MAD stands for but it's an animation compilation? #o and check out ''the canipa effect'' its a good channel

[chiyamabunny]

Mamo Blog - 2018/5/31 (Eng. Translation)

NHK「シブヤノオト」出演!! NHK "SHIBUYA NOTE" Appearance!! 2018/5/31 20:09

NHKの音楽番組、 NHK's music program,

「シブヤノオト」 "SHIBUYA NOTE に、わたくし宮野真守、 In it, I, Miyano Mamoru,

出演させていただきます!! Will be a performing!!

新曲「EXCITING!」を、 The new song "EXCITING!,"

チ���ムマモのダンサーズと���フォーマンスさせていただきましたψ(｀∇´)ψ☆ I'll be performing with Team Mamo's dancers ψ(｀∇´)ψ☆

みんなに、 Everyone,

テレビの前で、 In front of the television,

一緒盛り上がって貰えたら、 If we could get excited together,

めちゃくちゃ嬉しいです☆☆☆ I'll be super happy☆☆☆

MCの徳井義実さん、渡辺直美さんとも、 The MCs, Tokui Yoshimi-san and, Watanabe Naomi-san as well,

とっても楽しくトークさせていただきました(*≧∀≦*) We had a very fun talk(*≧∀≦*)

笑ったなぁ（笑） I laughed a lott（lol）

是非注目していて欲しいです♪ By all means, I'd like you to watch it♪

放送日時は、 The broadcasting date is,

6月3日（日）午前0時05分～0時58分〈土曜深夜〉 June 3rd (Sun.) 0:05～0:58〈Saturday Midnight〉

です!! Is what it is!!

是非とも、ご覧下さい♪ By all means, please watch it♪

よろしくお願いいたします＼(^o^)／☆☆☆ yoroshiku onegaiitashimasu＼(^o^)／☆☆��

#miyano mamoru #seiyuu #mamo blog #EXCITING! #translation

[newsintheshell]

“Mahoujin Guru Guru: Magical Circle”

Serie TV anime, 12 luglio 2017

Nuovo adattamento del manga “Mahoujin Guru Guru” (Guru Guru - Il girotondo della magia) di Hiroyuki Eto.

-STAFF-

Regia: Hiroshi Ikehata 

Assistante di regia: Tetsuaki Watanabe 

Sceneggiatura: Hisaaki Okui 

Character Design: Naoyuki Asano 

Sub Character Design: Asuka Yamaguchi 

Monster Design: Asuka Suzuki 

Prop Design: Natsuki Wada 

Fondali: Seiki Tamura 

Direttore artistico: Shinichi Uehara 

Colorazioni: Emiko Ueno 

Direttore della fotografia: Tetsuya Takahashi 

Montaggio: Yoshinori Murakami 

Direttore del suono: Jin Aketagawa 

Produzione sonoro:: Magic Capsule

Produzione musicale: Lantis

Musiche: TECHNOBOYS PULCRAFT GREEN-FUND

Sigla di apertura: ORESAMA “Trip Trip Trip” Sigla di chiusura: TECHNOBOYS PULCRAFT GREEN-FUND feat. Bonjour Suzuki

-CAST-

Nike: Shizuka Ishigami 

Kukuri: Yoshimi Ohara 

Edvarg (Kita Kita Oyaji): Katsuyuki Konishi 

Juju: You Taichi

Toma: Yukiyo Fujii 

Gipple: Takahiro Sakurai 

Runrun: Saori Ōnishi

Sōsai: Akira Ishida

Raid: Nobuhiko Okamoto 

Eto ha lanciato l’opera nel 1992 che è stata serializzata sul mensile fino al 2003, concludendosi con il 16° volume. in Italia il manga è stato inizialmente distribuito da Dynamic Italia/Dynit, ma la pubblicazione non è mai stata completata. Nel 2012 è stato lanciato sul sito Gangan Online il sequel “Mahoujin Guru Guru 2″ e Square Enix ne pubblicherà il 7° volumetto il 21 gennaio.

La popolare parodia di Eto, ispirata ai classici giochi di ruolo fantasy è stata già trasposta in due serie tv anime, la prima omonima del 1994 (in Italia trasmessa su Rai 2 nel 2001), la seconda del 2000 ed intitolata “Doki Doki Densetsu Mahoujin Guru Guru”, trasmessa a sua volta su Rai 2 nel 2004 con il titolo “Guru Guru - Batticuore della magia”. Nel 1996 è uscito anche un corto di 30 minuti, rimasto però inedito da noi.

Sito ufficiale

SilenziO)))

#mahoujin guru guru magical circle #mahoujin guru guru #anime #serie tv #estate 2017 #guru guru il girotondo della magia