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#Artificial Immunity
dockwish9 · 2 years
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'waning' Immunity
Alabama has about 421,000 children ages 5-11, according to the Census Bureau. The predominant association of sapovirus gastroenteritis with people in youthful age teams means that immunity to sapoviruses may be acquired early in life. In between now and then, COVID-19 instances and deaths could move on a rollercoaster-like trajectory, decreasing for intervals then rising again when restrictions become more relaxed and extra unvaccinated individuals begin to gather in large teams. Why the IRGs are such a big family of proteins in the murine genome and so decreased in humans, or if useful counterpart exists in people, is not yet clear. While vaccine hesitancy is a big barrier to herd immunity, this is simply part of the uphill climb. The longer the virus stays in our communities, the greater the chance it has to mutate into other variants that could make it tougher to defend against. Among the reported barriers, some people selected to not obtain the second shot as a end result of they feared unwanted aspect effects. Outbreaks often begin with an imported case (someone who was travelling outdoors the U.S.) or particular person coming into contact with an unvaccinated individual or folks. Epishield Plus Review contaminated individuals then expose unprotected folks to the disease. A massive percentage of the inhabitants will must be immune towards the disease earlier than herd immunity shall be achieved. It is not known when that may occur, however it'll depend upon how many individuals get vaccinated. For the primary time in two months, COVID-19 case counts and deaths are rising again in most U.S. states, especially in the northern tier and Rocky Mountains, in accordance with a USA TODAY evaluation of Johns Hopkins University data. The immune system protects us from invading pathogenic microorganisms and cancer. While you can obtain an annual flu vaccine, the virus mutates with such frequency that antibodies last months as an alternative of years. New variants, which could be more resistant to vaccines, are often rising. It’s not clear how lengthy you would possibly be shielded from getting sick again after recovering from COVID-19. When a B cell encounters an antigen, it is stimulated to mature right into a plasma cell or a reminiscence B cell. The main function of B cells is to supply antibodies, which tag an antigen for attack or instantly neutralize it. B cells can also current antigen to T cells, which then become activated. As a service to our readers, Harvard Health Publishing provides access to our library of archived content material.
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coalokra9 · 2 years
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Immunity Inc
The mineral plays an essential position in the growth and maintenance of immune system perform, but the exact mechanism of its action just isn't but known. Epishield Plus Review has antimicrobial properties, accumulates at websites of irritation, and should play a task in the innate immune response to bacterial infections . Copper deficiency results in neutropenia, an abnormally low number of neutrophils , which may enhance one’s susceptibility to an infection. Adverse results of inadequate copper on immune function seem most pronounced in infants. Infants with Menkes disease, a genetic disorder that results in severe copper deficiency, endure from frequent and extreme infections . According to a report by the American Psychological Association, long-term stress weakens the responses of your immune system. Washing palms for 20 seconds and training social distancing are key to stopping the unfold of the virus. However, it's also essential to have a robust immune system that may struggle back towards the germs you may encounter. In the midst of the COVID-19 pandemic, many are taking further precautions to remain healthy. View a worldwide coronavirus tracker with knowledge from Johns Hopkins University. However, if a selected variety of people in a inhabitants are immune, then the pathogen’s chain of transmission is damaged and the illness can't be passed round as easily. As a result, the illness becomes rarer over time and might even be eradicated altogether. Typically, vaccines corresponding to those that combat COVID-19 introduce harmless components of the virus to elicit T and B cell manufacturing by the body’s adaptive immune system, which can recognize earlier pathogens and mount a focused response. Treatments corresponding to monoclonal antibodies additionally purpose to mimic this later-stage immune response. That estimate took into consideration the vaccination rate and the vaccines’ effectiveness. The killer cell must migrate to the location of infection and directly bind to its target to make sure its destruction. Central to each categories of immune responses is the flexibility to differentiate foreign invaders from our own tissues, which must be protected. Because of their ability to reply rapidly, the innate responses are normally the first to respond to an “invasion.” This initial response serves to alert and trigger the adaptive response, which might take several days to totally activate. When most of a population is proof against an infectious illness, this provides oblique protection—or inhabitants immunity —to those who are not proof against the illness. “The government’s response has been a disaster,” Hadi Ghaemi, govt director of the New York-based Center for Human Rights in Iran, informed The Daily Beast. In reality, billions of people all over the world have gotten the Western vaccines. In other words, it’s possible—likely, should you consider the research—that several occasions as many Iranians are dying of COVID than the government is reporting.
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brasspage4 · 2 years
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Science & Tech Highlight
Active immunity could be acquired via pure immunity or vaccine-induced immunity. Some reviews describe reinfections of the novel coronavirus in people who examined optimistic again after that they had already recovered. It’s not clear, although, that these are literally cases of reinfection—it’s extra likely that they are often defined by people continuing to shed the virus for a really long time, and that the extent of virus shedding fluctuates over time. If the risks of COVID-19 weren't so high, it would technically be potential to result in herd immunity by permitting the illness to run rampant by way of a inhabitants. However, proof shows that scenario would lead to high charges of hospitalization and wish for critical care, straining health service capability past the breaking level. That’s why antibody checks shouldn’t be overinterpreted, Iwasaki says. This number of infections may result in critical issues and hundreds of thousands of deaths, particularly among older people and people who have present well being circumstances. Modern drugs has come to understand the carefully linked relationship of thoughts and physique. A extensive variety of maladies, including stomach upset, hives, and even heart illness, are linked to the results of emotional stress. "Logistically, permitting people to substitute prior infection for vaccination requires documentation of prior infection and present antibody status," Forman mentioned. "And then making a decision about sturdiness — i.e. how long can somebody be thought-about to nonetheless have immunity." Dr. Howie Forman, a professor of radiology and public well being at Yale University, advised Yahoo Finance that there are "important" caveats that should be taken into consideration with natural immunity. However, some research have reported no beneficial adjustments in leukocyte production or perform with vitamin C remedy ( ). Neutrophils, mononuclear phagocytes, and lymphocytes accumulate vitamin C to high concentrations, which might defend these cell varieties from oxidative harm . Vitamin C, via its antioxidant functions, has been proven to protect leukocytes from such effects of autooxidation . The report also notes that there isn't a take a look at licensed by the Food and Drug Administration that may enable doctors and the common public to reliably measure an individual’s protection from illness. And although higher levels of neutralizing antibodies typically sign larger protection, scientists don’t know exactly what level of antibodies will shield an individual. Human skin capabilities as a bodily, chemical, and immune barrier in opposition to the exterior environment whereas also providing a protecting niche for its resident microbiota, generally identified as the skin microbiome. In Tonicgreens , we describe the function of the microbiome in microbe, host, and immune interactions underneath distinct pores and skin states, including homeostasis, tissue restore, and wound an infection. For instance, if a disease is taken into account extremely contagious, a higher proportion of immunity is needed. Measles, a particularly contagious disease that's preventable through vaccination, wants percent4 of a inhabitants to be immune so as to reach herd immunity threshold and for measles to be eliminated. Immunity from a prior an infection has been a vexing problem for the Biden administration as it continues to push vaccinations as the key to ending the pandemic. Some Republican members of Congress have seized on what they term “natural immunity” to push back in opposition to the vaccine mandates favored by the White House. Although each fragments of SEB had been highly immunogenic, the fragments failed to guard mice whether they were injected individually or injected together.
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bitekendo8 · 2 years
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Infection And Immunity Journal Homepage
Each infectious exposure leads to training of the cells so that a response to a second publicity to the identical infection is extra rapid and larger in magnitude. We have seen that the restrictions needed over time have varied as preventive measures have labored to drive an infection rates down, but we have additionally seen these rates resurge as our responses have relaxed. [newline]Once we get sufficient individuals vaccinated to drive down an infection rates more persistently, we must always be able to steadily lift these restrictions. But till the vaccine is extensively distributed and a large majority of the population is vaccinated, there'll still be a danger of infection and outbreaks—and we will need to take some precautions. In the treatise, Al Razi describes the clinical presentation of smallpox and measles and goes on to point that publicity to these particular agents confers lasting immunity . Passive immunity is supplied when a person is given antibodies to a disease rather than producing them through his or her personal immune system. Vaccine-induced immunity is acquired through the introduction of a killed or weakened form of the disease organism by way of vaccination. “The drawback with coronavirus is that no-one has had it earlier than, regardless of age,” says Gostic of the University of Chicago. It’s nearly as if hen pox had simply emerged for the primary time, leaving adults extra vulnerable to the more severe cases that come with age, she explains. Demonstrating whether or not an herb — or any substance, for that matter — can improve immunity is, as yet, a highly sophisticated matter. Scientists do not know, for instance, whether an herb that appears to boost the levels of antibodies within the blood is definitely doing anything beneficial for total immunity. Like any fighting drive, the immune system military marches on its abdomen. Scientists have lengthy recognized that individuals who reside in poverty and are malnourished are extra weak to infectious ailments. For instance, researchers don't know whether or not any particular dietary factors, corresponding to processed meals or excessive easy sugar consumption, will have adversely have an effect on immune operate. There are nonetheless relatively few research of the effects of diet on the immune system of people. A easy RNA molecule jumpstarts the immune system’s “first responders” to viral an infection and may even eradicate the SARS-CoV-2 virus in mice with persistent cases of COVID-19, a model new Yale School of Medicine research finds. Childhood illnesses such as measles, mumps, diphtheria, polio, chickenpox, and so on., all reached herd immunity by way of this strategy. We have seen measles outbreaks in communities who have misplaced herd immunity due to anti-vaccine actions. Tonicgreens Review imagine vital info must be seen by the folks impacted, whether or not it’s a public health crisis, investigative reporting or maintaining lawmakers accountable.
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cicadaangle35 · 2 years
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Immunity Definition & That Means
Immunoglobulin therapy continued to be a primary line remedy in the therapy of extreme respiratory diseases till the 1930s, even after sulfonamide lot antibiotics were introduced. The first scientist who developed a full theory of immunity was Ilya Mechnikov who revealed phagocytosis in 1882. With Louis Pasteur's germ principle of disease, the fledgling science of immunology began to clarify how bacteria triggered illness, and how, following infection, the human body gained the ability to resist further infections. Innate immunity, also identified as native immunity, is a semi-specific and widely distributed type of immunity. It is defined as the primary line of protection against pathogens, representing a crucial systemic response to stop an infection and keep homeostasis, contributing to the activation of an adaptive immune response. It does not adapt to particular exterior stimulus or a previous infection, however depends on genetically encoded recognition of explicit patterns. In response, we create substantial new ones (anti-virals), and but we proceed to undermine our own efforts by doubting the most recent science and insisting on our proper to be non-compliant. We additionally know that the most effective tools we have to fight it are vaccines, artificial antibodies and, now, the rising antiviral medication made by Merck and especially Pfizer, which stop the virus from reproducing earlier than the dreaded inflammation occurs. Mary Hannah Swaney is a Ph.D. candidate in the Department of Medical Microbiology and Immunology at the University of Wisconsin-Madison in Madison, WI. She received her B.S. In Biochemistry and Molecular Biology at Pennsylvania State University, the place she studied a small molecule inhibitor of the trans-translation pathway in micro organism. Her current interests embrace elucidating the microbe-microbe and microbe-host interactions answerable for sustaining skin microbiome stability and performance, with a selected focus on vitamin B12. All animals face the issue of stopping pathogen development whereas maintaining helpful microbiota on their most fragile epithelium. However, it's nonetheless poorly understood how organisms remedy this conundrum. Animals depend upon numerous mechanisms that discriminate between self and non-self, respond to tissue damage, include and remove non-self, and heal damaged tissues. About half of the beforehand infected U.S. adults haven't been vaccinated, according to a survey of antibody ranges and history of vaccination amongst blood donors between January and August. The CDC published an outline of the current information on infection-induced and vaccine-induced immunity to COVID-19, which incorporates proof from greater than ninety peer-reviewed and pre-print publications, as nicely as unpublished data from the CDC. Social immune mechanisms are unlikely to be conserved at a molecular stage between bugs and mammals; but quite, social methods may have independently advanced their own solutions. Thus, in tightly-knit teams like those formed by social species, the additive impact of individual sanitary responses, be they immune or behavioural, generates a “communal immune system” resulting in the mitigation of pathogen transmission. Scattered reviews of reinfection with SARS-CoV-2 have raised issues that the immune response to the virus may not be durable. It curbs the levels of stress hormones in your body and boosts a sort of white blood cell that fights infection. There's Flexobliss Review name them "man's best good friend." Dogs and other pets aren’t just good buddies. They additionally give us a purpose to exercise and increase our health in different ways. In the summer time of 1918, the farmers and ranchers of Kansas fought two illnesses directly. Six months earlier, in January, circumstances of what came to be known as the Spanish Flu had bloomed throughout Haskell County, in the southwest of the state . That same summer season, veterinarian George Potter wrote a few second disease, attributable to the bacterium Brucella abortus, that triggered contagious and spontaneous abortions in cattle and threatened Kansas’ cattle trade throughout the early 1900s . Potter really helpful that farmers not kill sick cows, as a outcome of individual females would clear the infection on their very own. Therefore, letting an an infection run its course would result in “herd immunity,” Potter surmised, which means that once enough cows developed immunity, the illness would come beneath management and not trouble the rancher. Potter was among the first to coin the term, based on a history printed in The Lancet in 2020 .
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frownteeth51 · 2 years
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What We Know So Far About Waning Vaccine Effectiveness
It can additionally be given medically through blood products that include antibodies, such as immune globulin. This type of immunity is quick performing but lasts just a few weeks or months. Innate immunity is the immune system that's present if you finish up born. In the united states and elsewhere, booster vaccination may become needed if variants arise that can evade the immune response provoked by current vaccines. In the worst case , we will proceed to see further waves of surging an infection. The virus will infect—and kill—many more people earlier than our vaccination program reaches everyone. The extra individuals the virus infects, the more chances it has to mutate. While many parts of the nation and state have low vaccination rates, the Bay Area is considered one of the most highly vaccinated areas within the nation. And these rates are climbing additional now that hundreds of newly eligible kids 5 to 11 years old are getting pictures. So the area has the luxurious of turning to boosters, that are in ample provide, as a further layer of safety. But each the English and Canadian studies discovered that even after several months, the Pfizer-BioNTech and Moderna vaccines remain highly effective at stopping hospitalization. But the act does not offer any suggestion for how agencies would verify immunity from prior infections or incorporate such immunity right into a vaccine policy. Flexobliss Reviews create resistance, and this resistance becomes extra necessary to some than the actual query of whether or not the science works or not. I know of one physician who had COVID twice and who took the primary dose of the vaccine however was so sure she didn’t need the second dose that she risked sacrificing her job somewhat than take the second shot. It was solely when she realized that her response was to the arbitrary, unjust imposition of a blind authority, quite than to the risk of the shot itself, that she determined lastly to take that second shot in order to maintain working. The simply transmitted delta variant has raised the stakes of the battle whereas on the similar time exposing the restrictions of our weapons.
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sharklunch9 · 2 years
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National Cancer Institute
Among https://supplementlegend.com/vitalitox-review/ who have been absolutely vaccinated, 324 (or 5.1 percent) had a constructive COVID-19 PCR check. Among the 1,020 who were unvaccinated and who had beforehand had the infection, 89 (or 8.7 percent) had a positive COVID-19 PCR check. This summer season they experienced a “fourth wave” of the Delta variant of COVID-19 together with those who had been allegedly “protected” by the vaccine. Israel has over 1.three million individuals who received sick from the virus and 8,one hundred thirty who died. The system offers a digital copy of state vaccine data according to the net site. Even with these low rates, the CDC recommends vaccination quite than natural infection. That the safety supplied by vaccines diminishes over time — particularly in the face of the delta variant — is now well known. But new research on immune safety for people previously infected with coronavirus also performed a job within the modeling team downgrading the state’s safety stage. Just as a herd of cattle or sheep uses sheer numbers to protect its members from predators, herd immunity protects a community from infectious ailments by virtue of the sheer numbers of individuals immune to such illnesses. The more members of a human "herd" who are immune to a given disease, the better protected the whole populace will be from an outbreak of that illness. It would have been better to gather a quantity of blood samples from every participant. STAT requested a number of specialists to map out situations of how we'd come to coexist with this new risk. In a time of uncertainty, the eventualities they sketched have been actually hopeful, even if the relief most envisage just isn't instantly around the corner. Screen for heightened danger individual and entities globally to help uncover hidden risks in enterprise relationships and human networks. Access to real-time, reference, and non-real time information in the cloud to power your enterprise. If you’re totally vaccinated, you'll find a way to return to doing actions you might not have been in a position to do because of the pandemic, together with not wearing a mask or social distancing in any setting — except the place required by a rule or regulation. However, if you are in an space with a excessive number of new COVID-19 instances within the final week, the CDC recommends carrying a masks indoors in public and outside in crowded areas or if you end up in shut contact with unvaccinated people. It is the one class of antibody that crosses the placenta from mother to fetus. He is interested in understanding the mechanisms by which alternative complement pathway function supports host defense—particularly at the interface of the host and pathogen—and patient survival during crucial illness. T cell immunity is similar with both vaccine, with Covaxin outpacing Covishield when it comes to Delta variant immunity. Natural immunity produces comparably environment friendly mobile immunity and even better towards the Delta variant. But even under any “herd immunity threshold,” immunity within the inhabitants can still have a positive effect by decreasing the entire variety of infections that happen. When most of a inhabitants is resistant to an infectious illness, this offers indirect protection—also referred to as inhabitants immunity, herd immunity, or herd protection—to those who usually are not resistant to the disease. Attempting to boost the cells of your immune system is especially difficult as a outcome of there are so much of totally different kinds of cells within the immune system that reply to so many different microbes in so many ways. What is known is that the physique is regularly producing immune cells. Certainly, it produces many more lymphocytes than it can possibly use.
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roofbelt8 · 2 years
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A Potential Role For Ibuprofen In Older Adults Immunity To Rsv
Moreover, vitamin E supplementation in extra of current consumption suggestions has been proven to boost immunity and decrease susceptibility to certain infections, particularly in aged individuals. It is a fancy and built-in system of cells, tissues, and organs that has specialised roles in defending against overseas substances and pathogenic microorganisms, including micro organism, viruses, and fungi. The immune system also capabilities to protect towards the development of most cancers. For these actions, the immune system should acknowledge overseas invaders, in addition to abnormal cells and distinguish them from self . However, the immune system is a double-edged sword in that host tissues could be damaged within the process of combating and destroying invading pathogens. A key component of the quick immune response is inflammation, which can cause injury to host tissues, although the harm is normally not significant . This winter and the most effective methods to enhance your gut well being and sleep. There are, however, methods to assist and strengthen your immune cells and their critical functions—this takes some work, in fact, however integrative household physicianMadiha Saeed, M.D.,says you can start with meals. Good habits that keep your thoughts healthy—which is often how we perceive self-care—can also keep your body wholesome. With immunity so top of mind right now, it solely is sensible that we're trying to find more ways to maintain ourselves wholesome from the inside out. Understanding how Vitalitox Review may work together and whether or not protection could be additive has yet to be answered. This article will arm the microbiologist not with a storehouse of data, the traditional aim of an encyclopedia, but with a fundament of understanding with which to read the larger literature of immunity. While many people who get COVID-19 get well within a few weeks, there is a portion who suffer from post-COVID-19 syndrome, a new term used to describe sufferers who reside with lasting signs from the coronavirus. To learn extra about this new medical drawback, we explored what causes these long-term symptoms, who's most affected and what the physical effects seem like in post-COVID-19 patients. The reality is, many Americans could merely opt to not receive the vaccination for personal causes. Each yr, between forty five and 50 % of Americans 18 and older receive the flu vaccine. B cells have specific sites on their surface where antigens can connect. B cells can be taught to recognize an almost limitless variety of totally different antigens. When T cells initially encounter an antigen, most of them perform their designated perform, however a few of them develop into reminiscence cells, which bear in mind the antigen and respond to it extra vigorously after they encounter it again. Killer T cells then kill these cells by making holes of their cell membrane and injecting enzymes into the cells. After they first encounter an infected or abnormal cell, they're activated and search for these explicit cells. Acquired immunity takes time to develop after first publicity to a new antigen.
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mindblowingscience · 2 years
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Using new machine learning techniques, researchers at UC San Francisco (UCSF), in collaboration with a team at IBM Research, have developed a virtual molecular library of thousands of "command sentences" for cells, based on combinations of "words" that guided engineered immune cells to seek out and tirelessly kill cancer cells.
The work, published online Dec. 8, 2022, in Science, represents the first time such sophisticated computational approaches have been applied to a field that until now has progressed largely through ad hoc tinkering and engineering cells with existing—rather than synthesized—molecules.
The advance allows scientists to predict which elements—natural or synthesized—they should include in a cell to give it the precise behaviors required to respond effectively to complex diseases.
Continue Reading.
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selkies-world · 1 month
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Want to learn how to spot Ai art & images, in order to avoid falling for them???
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[First classes: 29th April, 1st May, 2nd May. All 3 will focus on character design]
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eccedeus · 3 months
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Something that really gets my goat about this recent wave of AI posts in particular, is people just mindlessly reblogging any posts containing "solutions" to "protect" artists. It really is just the gen z/millennial version of 'IM COPYING AND PASTING THIS TEXT TO STOP MARK SUCKIEBERG FROM OWNING MY PHOTOS AND PERSONAL DATA'
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thorne1435 · 9 months
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Remember kids: propaganda isn't inherently bad, nor is it always misinformation! It actually depends on the agenda itself and what the effects of the campaign are.
You aren't immune to insidious advertisements, but you also aren't immune to body-positivity posts, for example.
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clonerightsagenda · 1 year
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Also RIP Pride who got demolished in that poll. I think he's cool.
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theeflowerofcarnage · 11 months
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You know in hindsight I should’ve always known I would not like Paul in the second dune book. It was always there that he was not the “good guy” but I got too caught up in the messiah symbolism of it all my bad 🤡
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saint-ambrosef · 2 years
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boggles my mind how nobody seems to think there might be correlation between new covid strains growing progressively more immune to anti-bodies, and calling for people to get their sixth vaccine booster.
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tj-crochets · 2 years
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Hey y’all! I have a dilemma. Warning: talking about medical stuff
1. I might be finally getting a diagnosis for the adrenal problems! 2. It’s because I tested low on one thing, but it’s not the thing I thought I’d test low on 3. If I have the thing that being low on cortisol can mean, I not only *finally* have a diagnosis after more than a decade, I get the good meds 4. The good meds (a replacement for a different hormone than the one I’m already on) will almost definitely help literally all my other health problems, and there’s a chance that if I take them long term, I might not have allergies anymore?* 5. the problem: stress raises the levels of cortisol. Testing low on cortisol is how I get a diagnosis. I need to not panic before/during this blood test, and it involves being in a room for an hour and a bit because they have to take samples at different times to see how I react 6. It is very very difficult for me to not panic, knowing that if I *don’t* test low again, I will not get the diagnosis, and without the diagnosis I do not get the good meds (because if you don’t have Addisons, long term steroids are Very Bad for you in several ways, including messing up your immune system)  7. but if I DON’T have Addisons, and I am on the good meds, my immune system will be messed up in the middle of the pandemic 8. so I am stressing about potentially testing low, getting a diagnosis, having it be wrong and increase my covid risk, while also stressing about *not* testing low and being left a medical mystery again after coming so close to finally getting a diagnosis. It’s been twelve years since the first doctor told me I had salt issues, and nearly a decade since they got bad enough to affect my quality of life severely. I really, really want a diagnosis.  9. Either way, I really really need to not stress so that my levels are accurate, whatever they turn out to be So, tl;dr: I am stressing, and, for medical test reasons, it is very important that I not stress out for the next two days (so, until 6/22/22). To help me not stress, I am asking today for fanfic recs, and if y’all can send me like cute animal pictures and/or quilt inspiration on Wednesday morning? I’ll post about the cute animal pictures/quilt inspiration request tomorrow night so I can look at them in the morning *one of the roles of cortisol, as I understand it, is helping your body process histamines. I do not have IgE mediated allergies, I have “excess of histamine” allergies, so if I can process more histamine I might, functionally, be allergy free
#long post#medical mention#the person behind the yarn#I simplified some of this because I tend to go waaaaay into jargon when talking about my health issues#if anyone has any questions I'm happy to clarify I just wanted to de-jargon it as much as possible#Addisons disease is a kind of catch-all term for adrenal insufficiency. I have a family history of Addisons#I also have pretty severe stress reactions to most doctors for reasons I will not get into here#which means...my stress could have been tainting my test results the whole damn time (I have been tested for Addisons several times)#which is not helping my current stress levels lol#the 'good meds' I mentioned a few times are glucocorticoids (it could be one of a few different medications)#I am currently on a mineralocorticoid#both are steroids but are also artificial versions of hormones our bodies usually produce#if you take them and are low on them they have basically no impact on your immune system (as I understand it)#but if you take them and aren't low on them they are immunosuppressants (I am not a doctor though so don't take that as medical advice)#I unfortunately also get stressed out being in rooms with closed doors. Like rooms in doctor offices.#I have no explanation for that one? it doesn't bother me in bathrooms but absolutely does with kitchens/bedrooms/offices/etc#I think I read a lot of the major fandoms except anime ones (no judgment meant I just haven't watched them)#and probably not any based on games? again no judgment I just can't play a lot of games because they make me dizzy
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