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ghnservices · 1 year

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Multiple Myeloma Treatment in India

Multiple myeloma is a Blood disorder disease usually called Blood Cancer. Multiple myeloma can be treated by the Bone marrow transplant process.

In the initial stages of multiple myeloma, there are no symptoms but as the disease progresses, it may show some symptoms –

• Bone Fractures

• Bone pain

• Tiredness/fatigue

• Appetite loss/ weight loss

• Kidney function problems

What is Multiple myeloma?

Basically, Multiple myeloma releases chemicals that create an imbalance in bone destruction and bone formation. This may cause a hole in bones or bone thinning.

Multiple myeloma generally occurs in men than women. It is gradually increasing in urban India.

What causes multiple myeloma?

There is a condition known as monoclonal gammopathy of unknown significance. Where there is an excess of protein molecules, called immunoglobins, in your blood.

Black people are more likely to develop multiple myeloma than other people.

Family history of multiple myeloma

Multiple myeloma diagnosed in the mid 60’s.

Procedure to diagnose of Multiple myeloma

Test and procedure to diagnose multiple myeloma –

Blood Test – In this test, it may reveal M Proteins produced by myeloma cells.

Urine Test – Anaylsis of your urine test may show M proteins

Imaging Test – This test may be recommended to check bone problems associated with multiple myeloma. It may include X-Ray, CT Scan, MRI

Treatment of Multiple myeloma

Different types of doctors work together to create a patient’s overall treatment plan that combines different types of treatment.

Treatment plan may include different phases –

Induction therapy – for rapid control of cancer and to help relieve symptoms.

Chemotherapy or Bone marrow transplant/ Stem cell transplant

Maintenance therapy – over a long period of time to prevent cancer occurrence.

Types of medications used for multiple myeloma –

Chemotherapy - a drug treatment that uses powerful chemicals to kill fast growing cells in your body.

Targeted Therapy - a type of cancer treatment, that uses drugs to target specific genes and protiens that help cancer cells survive and grow.

Steriods - An anti-inflammatory medicines used to treat a range of conditions.

Immunotherapy - a type of cancer treatment that increases immune system to fight cancer. It helps your body fight against infections.

Bone-modifying drugs

Stem Cell Transplant

Stem cell transplantation is a treatment choice for individuals with multiple myeloma. There are three general kinds of transplantation :-

● Autologous transplantation - The Stem cells are gotten from your own blood or bone marrow. This is the kind of transplantation that is generally ordinarily suggested for treating multiple myeloma.

● Allogeneic transplantation - The Stem cells or bone marrow are gotten from a donor with a tissue type matching yours. This kind of transplantation conveys exceptionally high risk and isn't suggested for the vast majority with numerous myeloma.

● Syngeneic transplantation - The stem cells or bone marrow are obtained from an identical twin. This is the ideal type of transplantation, albeit barely any individuals with different myeloma have an indistinguishable twin who can act as a donor.

Transplantation, when effective, prompts a reduction and drags out endurance; seldom, allogeneic transplantation fixes different myeloma. Notwithstanding, transplantation has a few limits. The high-portion chemotherapy given before transplantation generally neglects to kill all of the plasma cells, permitting the condition to backslide after transplantation. Such treatment likewise expands your gamble of serious contaminations and dying, which can be deadly.

Autologous foundational microorganism transplantation — Autologous stem cell organism transplantation alludes to transplantation with your own undeveloped cells. During this system, stem organisms are gathered and frozen for sometimes in the future. High-portion chemotherapy is then given to kill however many plasma cells as could be expected under the circumstances, and the stem organisms are defrosted and gotten back to your body. Foundational microorganisms can be acquired from the blood or the bone marrow; for this situation, getting them from the blood is liked, on the grounds that blood undeveloped cells move to tissues all the more rapidly and are less inclined to be tainted with malignant plasma cells.

As of now, autologous stem cell transplantation is appropriate for up to 50 percent of individuals with multiple myeloma. Autologous undeveloped cell transplantation isn't suggested for individuals with seething multiple myeloma (individuals with multiple myeloma who have no side effects).

Who treats multiple myeloma?

Orthopedic Surgeon, a doctor who uses surgery to treat diseases of bones.

Radiation oncology, a doctor who treats cancer with radiation therapy.

Medical oncologist, a doctor who treats cancer with medicines such as chemotherapy or targeted therapy.

Bone marrow transplant Specialist, a doctor who specializes in performing bone marrow transplants.

For any enquiry regarding Best Multiple Myeloma hospitals & doctors or multiple myeloma treatment in India, Connect with us via HELPLINE: +91 9818857545 for immediate assistance & support.

#multiple myeloma treatment in India #bone marrow transplant

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padiatrichaematologist · 3 days

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#bone marrow transplant

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daniamedicare · 6 days

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Bone Marrow Transplant Cost in India

Presently, bone marrow transplant cost in India is a surgery that is in its golden phase. All credit goes to the advancement of Indian medical science, the use of modern technology, and efficient medical professionals. Moreover, Dania Medical Solutions can help you find the best overall treatment from the best medical team in India.

Bone marrow is perhaps a soft and spongy tissue in the bone, especially in the thighs and hip area producing blood cells. Bone marrow transplant or BMT is a medical procedure used to transplant either the damaged or destroyed bone marrow with a strong and healthy one. The damages can occur due to several factors, including infection, diseases, and chemotherapy.

Hence, this surgery is also known as a stem cell transplant. It involves adopting the cells in the bone marrow and providing them to the patient or any other person.

The bone marrow contains immature cells in the tissue. These cells are red blood cells, white blood cells, and platelets. The red blood cells (RBCs) work to transmit oxygen and nutrients to the whole body. White blood cells (WBCs) provide immunity by fighting the infection. Platelets effectively form clots which further helps to prevent excessive bleeding. <<<READ MORE>>>

#bone marrow transplant #bone marrow transplant in india #bone marrow transplant cost in India

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drpawankumarsingh · 11 days

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Understanding Acute Lymphoblastic Leukemia: A Patient's Guide

Understand Acute Lymphoblastic Leukemia (ALL), a type of blood cancer. It explains what ALL is, the symptoms to watch for, and the basics of diagnosis and treatment. Learn how to manage life with ALL and where to find the best care. For those in need of specialized treatment, the guide highlights the importance of consulting the Best BMT Doctor in Gurugram for expert care and support.

#best bmt doctor #best blood cancer doctor in delhi #Bone Marrow Transplant #best bmt doctor in delhi

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yourcancerguru · 21 days

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Cancer 101: The Bare Basics to Know if You've Been Diagnosed with Cancer

What is Cancer and How Does It Develop?

Cancer is a complex and multifaceted disease characterized by the uncontrolled growth and spread of abnormal cells in the body. These cells, known as cancer cells, can invade and destroy surrounding healthy tissues, impairing the normal functioning of organs and systems. Understanding how cancer develops involves diving into the intricate interplay of genetics, hormones, environmental, lifestyle, and immune factors.

At its core, cancer begins when mutations occur within the DNA of normal cells. These mutations can be caused by many factors, including exposure to chemicals and carcinogens, hormone disruptors. ultraviolet radiation, infection, and other stressors that affect the immune system. Additionally, genetic predispositions inherited from one's parents can also contribute to the development of cancer. As a result, cells begin to divide uncontrollably, forming a mass or tumor.

Staging and Grading of Cancer

Staging and grading are essential components of cancer diagnosis and prognosis, providing valuable information about the extent and aggressiveness of the disease.

Staging

Staging refers to the process of determining the extent of cancer spread throughout the body. It involves evaluating the size of the primary tumor, whether it has invaded nearby tissues or organs, and whether cancer cells have spread to regional lymph nodes or distant sites. Staging helps clinicians classify cancer into different categories, each with specific treatment approaches and prognostic implications. The most commonly used staging system is the TNM system, which stands for Tumor, Node, and Metastasis. It assigns a stage based on the size and extent of the primary tumor (T), the involvement of nearby lymph nodes (N), and the presence of metastasis (M). Staging provides valuable information for both treatment planning and prognosis.

Grading

Grading, on the other hand, evaluates the microscopic features of cancer cells and tissues to assess their level of differentiation and aggressiveness. Different cancers have distinct grading systems tailored to their specific characteristics. Typically, cancer cells are graded on a scale from low to high based on how closely they resemble normal cells in terms of structure, organization, and function. Low-grade cancers consist of well-differentiated cells that closely resemble normal tissue and tend to grow and spread more slowly. In contrast, high-grade cancers consist of poorly differentiated or undifferentiated cells with abnormal features and tend to grow and spread more rapidly. Grading helps clinicians predict how aggressively the cancer is likely to behave and guides treatment decisions, with higher-grade cancers often requiring more aggressive therapies.

What is a Tumor Marker and How is It Used?

A tumor marker is a substance produced by cancer cells or by the body in response to cancer. These substances can be found in blood, urine, or tissue samples and can serve as indicators of the presence, progression, or response to cancer treatment. Tumor markers are often proteins, enzymes, hormones, or other molecules that are either produced by cancer cells themselves or released into the bloodstream as a result of the body's immune response to cancer.

While tumor markers are useful in cancer diagnosis and management, it's important to note that they are not always specific to cancer and can also be elevated in other conditions, such as inflammation or benign tumors. Therefore, tumor markers are typically used in conjunction with other diagnostic tests and clinical assessments rather than as standalone tools for cancer diagnosis. Many times they can be used as indicators for whether or not imaging is necessary during or after treatment. They can also be used to monitor recurrence of disease.

What are the Different Kinds of Imaging Used for the Diagnosis and the Continued Evaluation of Cancer?

Imaging plays a crucial role in the diagnosis, staging, and ongoing evaluation of cancer. Different imaging modalities offer unique advantages in visualizing various aspects of cancer, such as the location, size, extent of spread, and response to treatment. Here are some of the most commonly used imaging techniques in cancer diagnosis and evaluation:

X-ray: X-rays are one of the oldest and most widely used imaging techniques. They are particularly useful in detecting abnormalities in bones, such as fractures or bone metastases. X-rays can also provide insights into the presence of lung tumors or abnormalities in the chest cavity.

Computed Tomography (CT) Scan: CT scans use X-rays to create detailed cross-sectional images of the body. CT scans are valuable for detecting and characterizing tumors in various organs, including the lungs, liver, pancreas, and abdomen. They can also help in staging cancer by revealing the extent of tumor spread to nearby tissues and lymph nodes.

Magnetic Resonance Imaging (MRI): MRI uses powerful magnets and radio waves to generate detailed images of soft tissues, such as the brain, spinal cord, muscles, and internal organs. MRI is particularly useful in imaging the brain, spinal cord, prostate, and musculoskeletal system. It provides excellent contrast resolution, making it valuable for detecting and characterizing tumors and assessing their relationship to nearby structures.

Positron Emission Tomography (PET) Scan: PET scans involve the injection of a radioactive tracer, which is taken up by rapidly dividing cells, such as cancer cells. PET scans can detect cancerous lesions anywhere in the body and provide information about the metabolic activity of tumors. When combined with CT (PET-CT), PET scans offer a powerful tool for cancer staging, treatment planning, and monitoring treatment response.

Ultrasound: Ultrasound uses sound waves to create real-time images of internal organs and tissues. It is commonly used to evaluate tumors in the breast, thyroid, liver, kidneys, and reproductive organs. Ultrasound is also used for guiding minimally invasive procedures, such as biopsies or needle aspirations, to obtain tissue samples for further analysis.

Mammography: Mammography is a specialized type of X-ray imaging used for breast cancer screening and diagnosis. It can detect breast tumors at early stages, often before they can be felt during a physical examination. Digital mammography and 3D mammography (tomosynthesis) are advanced techniques that provide higher sensitivity and improved image quality compared to traditional film mammography.

Endoscopy: Endoscopy involves the use of a flexible, lighted tube with a camera (endoscope) to visualize the inside of hollow organs or cavities, such as the gastrointestinal tract, respiratory tract, or urinary tract. Endoscopic procedures, such as colonoscopy, bronchoscopy, or cystoscopy, allow for direct visualization of tumors, tissue sampling (biopsy), and therapeutic interventions.

These imaging modalities, alone or in combination, enable clinicians to accurately diagnose cancer, determine its stage and extent of spread, plan treatment strategies, and monitor response to therapy over time. Each imaging technique has its strengths and limitations, and the choice of imaging modality depends on factors such as the type of cancer, location of the tumor, patient's health status.

Benign versus Malignant

The primary difference between a benign and malignant tumor lies in their behavior and potential to cause harm.

Benign Tumors

Benign tumors are non-cancerous growths that do not invade nearby tissues or spread to other parts of the body.

They typically grow slowly and remain localized, confined to the tissue or organ where they originated.

Benign tumors are usually well-defined and encapsulated, with cells that closely resemble normal cells in structure and function.

While benign tumors may grow and cause symptoms depending on their size and location, they do not have the ability to metastasize or spread to distant sites in the body.

In most cases, benign tumors are not life-threatening, and they can often be removed surgically with minimal risk of recurrence.

Malignant Tumors (Cancer):

Malignant tumors are cancerous growths characterized by uncontrolled cell growth, invasion of surrounding tissues, and the potential to metastasize to distant organs and tissues.

Cancer cells in malignant tumors have undergone genetic mutations that disrupt normal cellular functions, leading to abnormal growth, division, and behavior.

Malignant tumors can invade nearby tissues and organs, infiltrating surrounding structures and impairing their function.

The hallmark of malignancy is the ability of cancer cells to metastasize, spreading to distant sites in the body through the bloodstream or lymphatic system. Metastasis can lead to the formation of secondary tumors in vital organs, complicating treatment and prognosis.

Malignant tumors are often less well-defined than benign tumors, with irregular borders and heterogeneous cell populations.

Cancer is a serious and potentially life-threatening condition that requires prompt diagnosis and appropriate treatment, which may include surgery, chemotherapy, radiation therapy, targeted therapy, or immunotherapy.

What is Metastatic Disease? Metastatic disease, also known as metastasis, refers to the spread of cancer from its original (primary) site to distant organs or tissues in the body. Metastasis is a hallmark of malignant cancer and significantly impacts prognosis and treatment options.

When cancer cells break away from the primary tumor, they can travel through the bloodstream or lymphatic system to other parts of the body, where they establish secondary tumors. The process of metastasis involves several steps:

Invasion: Cancer cells invade nearby tissues or penetrate blood vessels or lymphatic vessels, allowing them to enter the circulation.

Transport: Cancer cells travel through the bloodstream or lymphatic system to distant sites in the body. The spread of cancer cells to distant organs or tissues can occur early in the disease process, even before the primary tumor is diagnosed.

Colonization: Cancer cells settle and establish secondary tumors in distant organs or tissues. The ability of cancer cells to survive and thrive in a new microenvironment depends on various factors, including interactions with the local tissue environment, immune responses, and the acquisition of specific genetic alterations.

Metastatic disease is a significant concern in cancer management for several reasons:

Prognosis: The presence of metastases is often associated with a poorer prognosis and decreased survival rates compared to localized cancer. Metastatic cancer is generally more challenging to treat and may require more aggressive therapies.

Treatment Considerations: Treatment decisions for metastatic cancer depend on factors such as the location and extent of metastases, the type and stage of the primary tumor, the overall health of the patient, and individual preferences. Treatment goals may focus on prolonging survival, relieving symptoms, maintaining quality of life, or aiming for a cure in select cases.

Multidisciplinary Approach: Managing metastatic cancer often requires a multidisciplinary team of healthcare professionals, including medical oncologists, surgical oncologists, radiation oncologists, pathologists, radiologists, and supportive care specialists. Treatment plans may involve a combination of surgery, chemotherapy, radiation therapy, targeted therapy, immunotherapy, and palliative care to address the needs of the patient comprehensively.

While metastatic disease poses significant challenges in cancer care, advances in treatment strategies, including targeted therapies and immunotherapies, have improved outcomes for many patients with metastatic cancer. Research continues to focus on understanding the mechanisms of metastasis, developing new therapeutic approaches, and improving patient outcomes in metastatic disease.

Common Treatments for Cancer

The treatment of cancer often involves a combination of different modalities tailored to the specific type and stage of cancer, as well as individual patient factors such as age, overall health, and preferences. Some of the most common treatments for cancer include:

Surgery: Surgery involves the removal of cancerous tumors and surrounding tissues. It is often the primary treatment for solid tumors that are localized and have not spread to other parts of the body. Surgery may be curative if the cancer is detected early and completely removed, or it may be used to relieve symptoms, improve quality of life, or debulk the tumor before other treatments such as chemotherapy or radiation therapy.

Chemotherapy: Chemotherapy uses drugs to kill cancer cells or stop them from growing and dividing. Chemotherapy can be administered orally, intravenously, or through injections and may be given alone or in combination with other treatments such as surgery or radiation therapy. Chemotherapy is commonly used to treat cancers that have spread to other parts of the body (metastatic cancer) or cancers that are sensitive to chemotherapy drugs.

Radiation Therapy: Radiation therapy uses high-energy X-rays or other forms of radiation to kill cancer cells or shrink tumors. Radiation therapy may be delivered externally using a machine (external beam radiation) or internally through implants or radioactive substances placed directly into or near the tumor (brachytherapy). Radiation therapy is often used as a primary treatment for localized cancers or in combination with surgery or chemotherapy to improve outcomes.

Targeted Therapy: Targeted therapy targets specific molecules or pathways involved in the growth and spread of cancer cells. Unlike chemotherapy, which affects both cancerous and healthy cells, targeted therapy is designed to selectively target cancer cells while minimizing damage to normal tissues. Targeted therapy drugs may include monoclonal antibodies, small molecule inhibitors, or other targeted agents that interfere with specific cellular processes or signaling pathways.

Immunotherapy: Immunotherapy harnesses the power of the immune system to recognize and attack cancer cells. Immunotherapy drugs work by enhancing the body's immune response against cancer cells or by blocking immune checkpoints that prevent the immune system from recognizing and attacking cancer cells. Immunotherapy has revolutionized cancer treatment in recent years and has shown promising results in a variety of cancers, including melanoma, lung cancer, and certain types of leukemia and lymphoma.

Hormone Therapy: Hormone therapy is used to treat cancers that are hormone-sensitive, such as breast cancer and prostate cancer. Hormone therapy works by blocking the production or action of certain hormones that stimulate the growth of cancer cells. It may involve the use of hormone-blocking medications or surgical removal of hormone-producing organs (e.g., ovaries or testes).

Bone Marrow Transplantation: Bone marrow transplantation, also known as stem cell transplantation, may be used to treat certain types of cancer, particularly blood cancers such as leukemia, lymphoma, and multiple myeloma. It involves replacing diseased or damaged bone marrow with healthy stem cells from a donor (allogeneic transplant) or from the patient themselves (autologous transplant).

These are some of the most common treatments for cancer, but there are other treatment options depending on kind of cancer, stage/grade, etc... In the future, I plan on sharing more about this topic, but for now, I hope this blog has given you a simple breakdown of the disease, how it's diagnosed and evaluated, and the most common types of treatment.

#cancer #chemotherapy #radiationtherapy #immunotherapy #cancer surgery #stem cell treatment #bone marrow transplant #hormonedrivencancer #cancer treatment #eastwestintegrativeoncology #yourcancerguru #cancer diagnosis #integrative oncology

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transplantcounseller · 1 month

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Bone Marrow / Stem Cell Transplantation In India | Transplant Counsellor

Bone marrow is the soft, sponge-like material found inside bones. It contains immature cells called stem cells that produce blood cells. There are three types of blood cells: white blood cells, which fight infection; red blood cells, which carry oxygen to and remove waste products from organs and tissues; and platelets, Transplant Counsellor dedicatedly providing best bone marrow transplantation services and surgeries in Delhi-NCR, India. The stem cell has a prominent role to play in the human body and thus in case of damage, the transplant is the best option. Stem cell transplant is basically the plantation of a new stem cell in the site body collecting it from the donor.

Bone Marrow Transplantation -Transplant Counsellor

Source Url: https://www.transplantcounsellor.com/bone-marrow-transplantation.html

#Bone Marrow Transplantation #Bone Marrow Transplant #Bone Marrow transplant in Delhi Ncr #Bone Marrow transplant in Delhi

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bereavedmum · 2 months

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Start of non invasive cpap

I am very much appreciating everyone’s prayers & words of encouragement thank you. Leah’s breathing is currently being assisted by something called “non invasive cpap“. Drs have told us that a ventilator may eventually become necessary. So far there has not been a significant response to the various treatments being used and this is worrying. Leah’s own immune system also needs to be able to…

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#bone marrow transplant #challenging time #immune system #Non invasive CPAP #prayer #praying #ventilator #words of encouragement

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indiamedicaltourism · 4 months

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Bone Marrow Transplant Cost in India

A bone marrow transplant is a medical procedure that substitutes bone marrow that has stopped producing sufficient healthy blood cells with viable blood-forming stem cells. A bone marrow transplant is commonly referred to as a stem cell transplant.

Bone marrow refers to the spongy, fatty tissue within your bones. The components of the blood it produces include:

Red blood cells transmit nutrients and oxygen across the body.

White blood cells, which help the body resist illness.

Platelets, which are primarily responsible for clot formation.

During a bone marrow transplant, the damaged stem cells are replaced with healthy ones. This enables your body to produce sufficient red blood cells, platelets, or white blood cells to avoid anemia, bleeding problems, or infections.

Healthy stem cells could emanate from a donor or even from your own body. In such situations, stem cells can get extracted or developed before undergoing chemotherapy or radiation therapy. Then, the healthy cells are preserved and used in transplants.

Bone Marrow transplant cost in India

Bone Marrow transplant price in India usually varies from 15 to 40 lakh rupees. The cost of a Bone Marrow transplant in India varies by several elements, including the transplant category, the donor form, the complex nature of the transplant operation, and the healthcare facility where the transplant is happening. This price includes the expenses of the transplant operation, hospital stay, lab testing, pharmaceuticals, and other associated expenses.

It's important to consider that a bone marrow transplant in India costs considerably less than it would cost abroad. This is because highly qualified doctors and modern technology are more affordable in India. Therefore, consider looking at all of the alternatives if you're searching for an inexpensive bone marrow transplant in India. However, you must ensure you get the best possible treatment and medication at a cost you can bear.

Best Bone Marrow transplant hospitals in India

Several government-financed and privately funded amenities in India conduct bone marrow transplants. The best Bone Marrow transplant hospital in India guarantees that patients obtain top-notch treatment. The Apollo Hospitals, Fortis Hospitals, and Tata Memorial Centre are some of the best hospitals for Bone Marrow transplants in India to perform this surgery. These hospitals satisfy the standards by providing top doctors access to state-of-the-art equipment and facilities.

Best Bone Marrow transplant Doctor in India

Bone marrow transplantation is a life-saving treatment that regains the haemoglobin levels of someone with Fanconianemia. This kind of transplant necessitates outstanding surgical ability and skills, as well as appropriate healthcare supplies, post-operative surveillance, and care. TheBest Bone Marrow transplants doctors in India specialise in bone marrow transplants are generally readily accessible and very skilled. The following are some of Best Doctors for Bone Marrow transplant in India:

Dr.GeetaKadayaprath of the Max Super Speciality Hospital in Vaishali, Ghaziabad

Doctor Rahul Bhargava

Doctor Nitin Sood

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Source: https://alafiyameditour1.blogspot.com/2023/09/bone-marrow-transplant-cost-in-india.html

#Bone Marrow Transplant

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