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#clarithromycin
odinsblog · 9 months
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jfc. a while ago i had a stomach infection and i went to my doctor and i didn’t know what was wrong, but i just asked her to please prescribe me some amoxicillin. she said that she couldn’t (bc why??) so instead she prescribed some other antibiotic medication that had a list of possible side effects as long as my forearm. most of the side effects were actually pretty severe and serious, but she was dead set against prescribing amoxicillin so i went with it. the one thing she said was, “listen odin, the side effect you’re most likely to have is strange weird dreams, and those can last anywhere from 4 to 6 months after you take the last pill in your regiment”
i was like lol wtf, but whatchagonnado when you need some immediate relief, right??
long story short, i took the pills she prescribed and they began to work almost immediately
but fam, the weird ass dreams !!!
i cannot even begin to tell you how weird they were
i usually dream about normal regular boring shit. you know, girls im currently crushing on (or ex girlfriends), being a superhero or being able to fly, the wellbeing or the death of loved ones, family squabbles, subconsciously working through problems at work … ya know, the usual boring mundane shit we all dream about
but man did these pills (clarithromycin?) really deliver on the “weird dreams” warning
i was dreaming crazy ass psychedelic shit like my feet being made out of cheese and/or bread(?!) or my ears emitting colorful huge balloons and people trying to put “sounds” in the balloons??
and the other day when i went to stay with my mom thru hurricane idalia, my mom woke me up in the middle of the night and i was literally screaming in my sleep!
i **know** that wasn’t a regular schmegular “nightmare” bc i don’t have nightmares (or at least, i haven’t had a real nightmare since my father died in my arms), and there was no feeling of fear or shock or anger that normally accompany nightmares
that weird shit ain’t my dreams
i’m certain it was the meds
like jfc, i’m only two months away from my last ingestion of those pills and i do not feel like another 2 - 4 months of this shit
i feel like i did drugs or shrooms or something
and this is coming from someone who has never done any drugs ever
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pharmaceutical0 · 7 months
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Clarithromycin - Impurity Standards - Simson Pharma
Clarithromycin is an antibiotic medication that belongs to the macrolide class. It is commonly used to treat various bacterial infections, such as respiratory tract infections, skin and soft tissue infections, and certain types of stomach ulcers associated with Helicobacter pylori. 
Simson Pharma is leading manufacturer and supplier of pharmaceutical Reference materials like Drug working standard, Drug impurity standards, Drug metabolites, and Stable Isotope Labelled compounds. Our expertise in this area has made us one of the most trusted companies in the industry.
Know More :- 
https://www.simsonpharma.com/promotions/clarithromycin-pharmaceutical-reference-standards-impurity-standards
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drpedi07 · 7 months
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Clarithromycin Drug
Medical information for Clarithromycin on Pediatric Oncall including Mechanism, Indication, Contraindications, Dosing, Adverse Effect, Interaction, Renal Dose, Hepatic Dose.
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centurypharma · 2 years
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If you are taking clarithromycin, you should keep some important points in your mind. clarithromycin exporters have inlined the facts of clarithromycin. Learn here when and how to take clarithromycin.
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parasyte-brainrot · 6 months
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hospital schmuck
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chemanalysta · 1 year
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Free Search Clarithromycin Prices online
The Clarithromycin Prices had taken an irregular trajectory in the North American region by the conclusion of the fourth quarter of 2022. In the first two months of Q4, prices were observed to be constant in the upper range due to strong market demand sentiments and favorable cost support from the operational side. Additionally, the supply-demand imbalance and regional inflation contributed to an increase in the price of Clarithromycin API. However, due to low demand and ample supply, prices began to decline later in December as inflation began to reduce. Towards the termination of Q4 2022, the values accessed at USD 261500/MT with an average quarterly inclination of 0.31%.
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nelfs · 1 year
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im going to get the antibiotics tomorrow because I’m supposed to catch up w people tonight and I can’t remember if the one they prescribed me makes me puke or not. my body HATES antibiotics it’s literally a gamble whether I get hives or heart palpitations from then
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tallymali · 10 months
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Don’t know if anon or messages is the better place to ask this. I have friend that’s had uti for 2 months and you came to mind. Would you mind telling your Dr/clinic and the new and previous meds you’re taking? Did both meds work & the new is just cheaper or does new work better also? Thank You Tally!
Oh my god, I'm so glad you've sent me this because I wish more than anything that I'd known about this illness so early on in experiencing it. I have soooo much to say about this so you're absolutely welcome to DM me and relay any questions your friend has.
Okay first off I definitely recommend your friend joins the facebook support group: www.facebook.com/groups/ChronicUTISupportGroup/
Even if they dont use facebook, they should totally just make an account to join. I didn't use it either so I just made a blank profile with a fake name. As long as you answer the questions they send, the mods should let you in with no problem. I said something like "apologies for the blank account, I don't use social media but I was told this is the best place for support" and I was accepted super fast.
So, the clinic I go to is the Harley Street chronic UTI clinic. They don't have their own website but all their info is here: www.chronicutiinfo.com/treatment/conventional-medicine/uk-treatment/prof-malone-lee/
(That website is also an incredible source of info on chronic UTIs)
You have to go there in person for the initial appointment, which costs £250. First thing they do is take your pee and analyse it under a microscope to get a count for white blood cells and epithelial cells. Then you go to the doctor's office (there's a team of doctors that all follow the same protocol) and they discuss your symptoms, any previous medications you've tried, and any other health issues you have. They will almost always prescribe Hiprex and a long term high dose antibiotic. Hiprex is a urinary antiseptic, and it essentially reacts with the acid in your urine to create formaldehyde. Most of us take high dose vitamin C pills with the Hiprex to keep our urine as acidic as possible (high bacteria in the bladder can raise urine pH so we often need help in that department).
At this point they will give you the prescriptions and say you can take them to your NHS GP and see if they're willing to fill them on the NHS. My GP didn't want to get involved with prescribing long term antibiotics, but was happy to fill the Hiprex prescription. I now get my antibiotics from Pharmacierge. Their prices are cheaper than regular pharmacies and they work closely with the Harley Street team. My doctor now just sends my prescriptions straight over to them which cuts out a little admin for me.
After that initial appointment you have to have a follow up appointment every 3 months, which can be done in person or over teams. Either way, they cost £200. If you go in person they will do the pee analysis again, but it's not super necessary to do that to monitor your progress. Patient symptoms are the number one thing they use to decide your treatment. Basically as long as you're in pain, they will keep treating you (the NHS would NEVER). Not a huge amount happens at these check ups, but being on long term antibiotics is risky so they will ask you a million questions about any possible side effects, and switch your meds immediately if you're not tolerating them well. They also ask that you contact your GP and request a blood test 3 times a year to monitor your kidney and liver function. They might also ask for other tests depending on your symptoms and the specific antibiotics you're prescribed.
So yeah, the treatment kind of just boils down to: find the right meds. Take them until you feel completely normal again.
As for the specific meds, here's a list of their most prescribed antibiotics:
Cefalexin
Amoxicillin
Co-amoxiclav
Nitrofurantoin
Trimethoprim
Doxycycline
Oxytetracycline
Azithromycin
Clarithromycin
Pivmecillinam
Lymecycline
For me, before starting treatment under Harley Street, I'd been treated by the Urology Partnership. They prescribed me 3 months of full dose Nitrofurantoin (brand name Macrobid, super common UTI treatment) and I was almost symptomless during that 3 months, but when I finished the course the symptoms returned instantly at full throttle. From that point they would only prescribe me the half dose of Nitrofurantoin which was NOT cutting it. That was when I decided to move to Harley Street. Definitely would not recommend Urology Partnership to people dealing with a chronic UTI.
SO. I emailed the Harley Street clinic with an appointment request and they booked me in for the next week. At my appointment the doctor prescibed Trimethoprim, which is usually the first one they try with new patients. I took it for a little while, (around 2 weeks to a month, I don't remember exactly) but I was still getting symptoms that weren't letting up, so I emailed their clinical enquiries address to let them know. I'd mentioned at my inital appointment that Nitrofurantoin had worked in the past, so they took me off the Trimethoprim and prescribed the Nitro instead, with the note that I'd have to discuss it at my next appointment.
Basically, Nitro is a really good antibiotic but has some of the nastiest side effects and is also the most expensive. So at my follow up appointment my doctor said he was happy for me to stay on it to get my symptoms back under control but he'd like to switch to a less risky antibiotic in time.
So a few months later (June this year) I was switched to Cefalexin, which has some of the least side effects and is one of the cheapest. I've been doing really well on it and I'm really feeling optimistic.
This is all to say that treatment is easy in theory but requires a little trial and error to find the right meds, and then takes a metric fucktonne of patience. There's no set length of time for the treatment, but in general, the longer you've had the cUTI the longer it takes to cure. So if your friend does have cUTI and can get treatment quickly, it shouldn't take too long to cure.
I had mine for two years before starting with Harley Street, which is actually much shorter than the average patient. They frequently treat older patients who have been suffering for over 20 years. I've read a depressing number of posts in the facebook group from people in their 50s+ who have been able to live normally for the first time in their adult life thanks to this treatment.
Knowledge of this condition with the general public AND with doctors (even urologists?????) is basically nonexistent. The NHS and most healthcare systems will slap you with a wastebasket diagnosis (PBS/BPS/IC) and tell you to piss off and live in pain forever. I genuinely don't think I will ever be able to trust a doctor right off the bat to actually prioritise my health ever again in my life. The NHS is full of people who really do care and really do everything they can for their patients but as an institution it does not give one iota of a fuck about the wellbeing of the people it's supposed to care about. It's a big complicated systemic issue but there will never be a good excuse for turning away patients who need medical care to live normally.
If your friend or literally anyone reading this is interested in the more academic/scientific side of this whole thing, I'd definitely read Cystitis Unmasked by Professor Malone Lee. It's written for doctors so it's not an easy read for a layperson but GOD it's so eye opening and infuriating. Professor Malone Lee is the guy who created the Harley Street UTI clinic and I think he spent his entire life raging at all the pillars of incompetance that modern UTI testing and treatment is built upon.
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sparksinger · 5 months
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long time no speak (again).
i have been ill for the last 10 weeks with a very annoying chesty cough. i was treated back at the beginning of november for bronchitis with amoxicillin (which did nothing) and then steroids and a stronger asthma pump.
then in the lead up to christmas, the cough got worse again and i started to bring up gunk. it was different in the sense of when i did cough, it felt like i was choking and like i couldn't get enough air in.
i went to the out of hours gp on christmas eve and she told me it was whooping cough. she gave me a week's worth of clarithromycin and more steroids.
i was really poorly over christmas week, puking on and off all day along with coughing my lungs up.
i still have the cough and they have now referred me for a chest xray to see if there is anything going on that there shouldn't be.
it's just getting on my nerves now.
hope anyone reading this had a peaceful/content holiday period. ♥
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I don't care how much the people on here love gum and sugarfree cough drops and suchothers, the amount of meds I have to take to prevent my guts from exploding and causing me everlasting pain is UNREAL.
And my guts STILL EXPLODE and STILL CAUSE ME EVERLASTING PAIN.
Honestly, I preferred my life and general health a lot more when I had made myself quite underweight. I really want to get back to my lw because life was so much better-
that aside, I am quitting gum and sugar-free cough drops, and also, I suspect unpasteurised honey is not helping and I'll have to replace that with actual antibiotics (sorry, mother, I prefer vomiting up clarithromycin for a few days than chronic diarrhoea, at least it makes me actually thinner).
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pharmaceutical0 · 11 months
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Clarithromycin- Pharmaceutical Reference Standards / Impurity Standards
Clarithromycin is an antibiotic medication that belongs to the macrolide class. It is commonly used to treat various bacterial infections, such as respiratory tract infections, skin and soft tissue infections, and certain types of stomach ulcers associated with Helicobacter pylori.
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thethingything · 2 days
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I think clarithromycin is going on the list of medications we tell doctors to absolutely never give us, alongside ciprofloxacin which is currently the only thing on the list, because we've had one fucling dose and immediately gone into a psychotic episode, started getting abdominal cramps so bad I almost ended up screaming and have nearly passed out from the pain, I haven't stopped shaking since I woke up about 5 hours ago, and I'm struggling to even talk properly out loud
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hickoryhorneddevils · 2 months
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clarithromycin kill yourself kill yourself kill yourself kill yourself kill yourself kill yourself kill yourself kill yourself. kill yourself
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Helicobacter Pylori
Spicing things up a bit with a Gram Negative Helical/spiral Bacteria
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Epidemio:
up to 50% of the population worldwide, but even more in endemic countries/the 3rd world
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it can cloud differentials, as it can be asymptomatic unless it caues peptic ulcer disease, in which case the infection may have been decades prior to detection - so you have to interpret serology with a grain of salt (it may not be the culprit of acute infection)
often picked up in early childhood and lingers without treatment for dcades
by contrast, 5% of children in the US have had it, so it may change your clinical decision making depending on where your patient grew up
In australian populations, up to 30% have it, but again, high frequency in older migrants, lower socioeconomic status etc.
Transmission:
faecal oral or even sexual (did not know that one)
increased risk:
lower socioeconomic status/growing up in a developed country
family history of infection and gastric cancer
What it does:
cause ulceration (peptic ulcer disease)
and inflammation or gastritis
due to it's helical shape and flagella, it can penetrate the mucosal lining
Trivia/History:
discovered by Australians in Western Australia in the 1980s
To quote the IM physician, Barry Marshall, in the face of skepticism that a bacteria could survive the stomach's acidic environment: "everyone was against me, but I knew I was right"
After failing to publish and some lab snaffus, he decided to do a Jonas Salk and swallow a broth of Hpylori himself. Of course this last experiment was published in an Australian journal.
At any rate, it is now widely accepted that Hpylori is linked to PUD and gastric cancer and by 2005, the two Australians who found the bacteria received the Nobel prize in medicine
we now know so much more about the pathogen with advancements in microbiology
they also came up with the urease breath test for it
Clinical presentation:
asymptoamtic
symptom onset occurs after gastritis and peptic ulcer disease develop: nausea, vomiting, dyspepsia, abdo pain, or at the extreme when the lining has eroded, bleeding/haematemesis
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IMage source
Important differentials
coeliac's
Crohn's
nSAID induced gastritis
reflux
lactose intolerance
eosinophilic oesophagitis (sooo rare, usually a/w dysphagia)
Investigations (all with relatively good/high sens and spec)
H pylori antigens in stool
serology (antibodies in serum, urine) --> usually IgG, hence can remain positive for years even post eradication
urease breath test
if a scope was involved due to PUD, then histopathology and culture (reduced sensitivity if treated with PPI in 2/52 prior or Abx 4/52 prior)
actually had no idea they breathed into little bags.
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Treatment:
triple therapy - PPI, amoxicillin and clarithromycin for 14 days, in penicillin allergy replace amox with metro (increasing resistance is why metro is not first line in some countries - refer to local guidelines made based on local Abx resistance trends)
In patients younger than 50, it can be cost effective to treat if they have reflux on testing (if there's a high pretest probability - see increased risk groups) given the life time risk of PUD & gastric cancer, can also reduce risk of GIB
balance of risk/benefit: will it significantly improve QOL or will risks of ADRs outweigh the benefits (eg frail, elderly, multiple comorbidities)
when used in those with PUD - improves ulcer healing, recovery and prevents relapse
in simple ulcers, triple therapy is all that is required in more chronic complex ones --> 8/52 of PPI is also recommended to prevent recurring of bleeding etc.
not treating can lead to relapse and complications like bleeding/perforation/cancer risk
Complications
rarely, it can cause gastric adenocarcinoma as a known carcinogen
aka MALT lymphoma - mucosa-associated lymphoid tissue
this resolves with triple therapy (Usually)
consider it in family histories of gastric cancer
life time risk of gastric cancer at 2% and 15-20% risk of peptic ulcer disease
Wish the acronym wasn't MALT. But could be a good way to remember it. MALT, tasty, gastritis and Hpylori.
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Follow-up
test for eradication 2 weeks post with stool antigen or urease breath test (serology less effective as the IgGs can remain positive for years) but that's on holding the PPI for 1/52 to prevent a false negative, some countries want both tests
in resistance or relapse there's salvage therapy, usually with bismuth or a quinolone.
Sources:
Wikipaedia - I havent covered pathophysio or it's cellular mechanisms and virulence factors, but there's a good overview in wiki
StatPearls (more paeds focused in this one)
CDC guidelines
Australian Therapeutic guidelines (Paywalll rest above are free)
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chemanalysta · 2 years
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By the end of this quarter, Q3 2022, the Clarithromycin Pricing had taken an erratic course in the APAC area. Prices were stable in the higher range at the start of the first month of Q3, with sound market demand sentiments and favorable cost support from the operational side. Additionally, the price of Clarithromycin API in the APAC region was impacted by the rising energy cost. Due to enough supplies and a reliable supply chain, prices decreased as September began. Furthermore, the weak market mood was caused by decreased downstream industry demand due to rising inflation. Towards the termination of Q3 222, the values accessed at USD 259280/MT with an average quarterly declination of 0.17%.
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melobin · 4 months
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Hi! this is not RIIZE related at all but can I ask what medicine did the doctor give you for tonsillitis?Hope you're feeling better tho x also did your pain affect the ear as well? x I was for 5 days but it's coming back 😪 at least I have Eunseok new ig pics which are 🥣
hi my lovely they gave me Clarithromycin. it made me quite sick too thought i don’t even think my tonsils have gone down or stopped sweeping 😭 the tonsillitis itself didn’t affect my ear but i woke up earlier today with an earache 😭 this has been a horrible experience,i hope you feel better soon my love 💓💞
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