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#solid tumors
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Amazing indeed! Read the whole thread.
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giyadesuza · 4 months
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https://www.merexpression.com/read-blog/132295
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drbanuprakashas · 2 years
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focusonthegoodnews · 2 years
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Failed Clinical Trial Leads to Scientific Breakthrough: Investigating Cancer Drug Toxicity Leads to Critical Discovery
Failed Clinical Trial Leads to Scientific Breakthrough: Investigating Cancer Drug Toxicity Leads to Critical Discovery
Good News Notes: “It’s not often that a failed clinical trial leads to a scientific breakthrough. When patients in the UK started experiencing negative side effects during a cancer immunotherapy trial, researchers at La Jolla Institute for Immunology (LJI) Center for Cancer Immunotherapy and University of Liverpool went back, examined the data, and worked with patient samples to determine what…
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tomorrow my friend's putting me in sfx makeup :D
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maraeffect · 5 months
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ugh i have scans in like 9 days and i wish they would just HURRY UP. i fucking hate waiting so much the weeks before. they were supposed to happen mid november but then i caught COVID so. it's my 6 months surgical "remission" scans so my chances of recurrence are especially high right now 🥲
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cloudshapedpatch · 2 years
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went to take off my work uniform and wholly forgot i had tits i think i gendered too hard today
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researchintelligence · 5 months
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mukulsoni1 · 5 months
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Solid Tumor Therapeutics: Market Dynamics and Future Outlook
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Understand the dynamics of the solid tumor therapeutics market and explore its future outlook. Stay ahead with insights into emerging therapies and market trends.
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giyadesuza · 4 months
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korattata · 10 months
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Appearently cabergoline tasts very very very very very very really bad
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mrunalnerkarblog · 1 year
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Growing advancement in cancer therapies to foster solid tumors treatment market growth
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Market Overview:
 A solid tumor can characterized by growth of abnormal mass or lump of tissues without liquid or cysts. It is classified into malignant tumor (cancerous) and the benign tumor (non-cancerous). Additionally, based on the cell type, tumors can be classified as sarcomas, carcinomas, and lymphomas.
Competitive Landscape:
Abbott Laboratories Inc., Biogen Idec Incorporated, AstraZeneca Plc., Johnson & Johnson Company, Amgen Inc., Bristol Myers Squibb Company, GlaxoSmithKline Plc., Sanofi, and Baxter International Incorporated
Key Market Drivers:
Growing popularity of biosimilars therapies is driving growth of the solid tumors treatment market. Moreover, rising prevalence of solid tumors is fueling market growth. According to the Centers for Disease Control and Prevention, in the United States in 2019, 1,752,735 new cancer cases were reported and 599,589 people died of cancer. For every 100,000 people, 439 new cancer cases were reported and 146 people died of cancer.
Growing merger &acquisition in the market of cancer therapies by key players is again contributing to market growth. For instance, in July 2022, Takeda announced that it has acquire Adaptate Biotherapeutics to develop novel Gamma Delta (γδ) T Cell Engager therapies targeting solid tumors.
Covid-19 Impact Analysis
The COVID-19 pandemic crisis has had significant impact on the practice of tumor treatment. There was disruption in supply of raw materials used for production of solid tumor drug due to lockdown and social distancing norms.
Key Takeaways:
1.      The solid tumors treatment market is expected to exhibit a CAGR of XX % over the forecast owing to the growing prevalence of solid tumors and increasing popularity of biosimilar. According to the IQVIA, the three most recently launched biosimilars in 2019 have achieved significant uptake within their first year: bevacizumab (42%), trastuzumab (38%), and rituximab (20%).
2.       North America is expected to gain significant growth over the forecast period owing to the presence of well-established healthcare sector.
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pramoja · 1 year
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bogleech · 3 months
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I wish every single person who owns over a billion dollars and every single person who has any degree of authority over any military in the world would just wake up with Devil Facial Tumor Disease tomorrow. That's the cancer Tasmanian devils get that grows over their faces until it seals their eyes and mouths shut, if you didn't know that already. I want to wake up tomorrow and see Biden and Trump on TV clawing at the solid masks of cancer swallowing their entire heads, is what I want to happen. If it does please remember not to help them, ok??? Just let them stumble around and slowly suffocate.
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rivetgoth · 6 months
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Black Alternative Music Recs
Not being Black myself, I hesitate to make myself a spokesperson specifically for Black alt artists as I don’t want to be tokenizing or reductive and I’d rather, like, uplift the voices of Black alt people than just make my own lists, BUT, I keep seeing people in the comments of recent posts about Death Grips asking for recs for more Black alternative artists, and I do know a good amount, so as a really basic list I wanted to throw out a few artists I really like—
Light Asylum: Darkwave. Really incredible vocalist, and openly queer. “Dark Allies” is a huge goth club hit but all of her work is great. I’ve seen her live twice and her live concerts are incredible too. One of the bigger Black goth artists.
Ho99o9: Punk/Industrial Hip Hop. Another big one, they’re pretty well known at this point but if you DON’T know them you should. Huuuge variety in sound here, all of it is so fun and solid, absolutely amazing energy.
clipping.: Industrial/Experimental Hip Hop. Really fun and catchy, great lyrics, great mixing, great experimental electronic sound.
Void Palace: Industrial/EBM. Local LA-based act with an amazing industrial dance club sound and vibe. Seen them live and they bring such cool but crazy energy. Really really solid.
O. Children: Darkwave/Post Punk. Really classic gothic sound, amazing vocals, really underrated, theatrical, fun, and moody gothic rock.
Izzy Spears: Industrial/Experimental Hip Hop. Openly gay alternative hip hop artist with a heavy and super danceable beat. I saw him live and he sounded great and had awesome punky energy.
LUSTSICKPUPPY: Punk/Electro-Industrial. Has almost a hyperpop sound sometimes, super high BPM high energy danceable electronic music with a really crazy theatrical style to their performances (kicking myself for missing them last year!). ETA: LSP uses they/them pronouns, corrected now but apologies for missing that irt any older iterations of this post floating around.
Baby Storme: Darkwave/Ethereal Pop. I think she got a bit of popularity on TikTok recently? I don’t use TikTok so idk, but she’s great. Really well mixed, fun, super solid dreamy darkwave with a dancey pop sound intermixed.
Grizz: Darkwave Hip Hop. I JUST discovered this artist, he’s another LA local who just put out a new single that’s getting some attention and he’s really good. Super cool goth fusion sound with really great classic darkwave electronic backing. Check him out!
Cold Gawd: Shoegaze/Post-Hardcore. Iconically sells merch that says “ABOLISH WHITE SHOEGAZE.” Absolute powerhouse of sound; I saw them live and their music sounded torrential, like this intense, powerful storm.
Debby Friday: Dark Electronic/Experimental Hip Hop. Really really haunting and dreamy gothic sound. Collaborates with artists like Boy Harsher. Superbly mixed. Lots of variety in sound but very consistently strong.
Dre Robinson: Industrial/Experimental Electronic. Longtime cEvin Key/Skinny Puppy collaborator. He was on stage with Skuppy during the recent live tour, doing sound and playing the maggot maracas (iykyk). He’s also been involved in a ton of cEvin’s solo work and accompanies him on stage for his live solo shows.
Charles Levi: Industrial/Industrial Rock. Wax Trax!/90s industrial icon, did work for My Life With the Thrill Kill Kult and Pigface. He’s recently had a bunch of serious health problems and has a GoFundMe up of you’d like to donate. He contributed to so much classic industrial rock, it’s crazy.
There’s a billion more. These are just some artists I genuinely really like personally who are Black, and I think all of them deserve a ton of support and recognition as contributors to the alternative scene. There’s so many amazing Black-fronted alternative bands and projects, and I’m just scratching the surface with artists I know and enjoy, Also considered listing some larger names like Yves Tumor and Tricky, but I feel they’re slightly more well known in the mainstream with ~1mil+ listeners on Spotify and I wanted to highlight some slightly more underground voices (to varying degrees—obviously some artists here are more well known than others).
Check them out!! Support Black alternative music!
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wheelie-sick · 1 month
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What is immunocompromisation?
Being immunocompromised means you have a weaker immune system than most people. There are two main ways people become immunocompromised
1. Medical Conditions
Certain medical conditions cause your immune system to be weaker. Some examples include:
Immunodeficiencies- A category of conditions causing a lower number of or lower efficacy of immune cells. This category is divided into two subcategories: primary immunodeficiency and secondary immunodeficiency. Primary immunodeficiency is a subcategory consisting of hundreds of different conditions all causing a lower number of immune cells. Secondary immunodeficiency is a smaller category consisting of conditions where a person lacks immune cells due to other causes such as malnutrition.
HIV/AIDS
Some cancers
2. Medications
There are two main types of medications that result in being immunocompromised: Immunosuppressants and chemotherapy
Immunosuppressive medications- Immunosuppressive medications are medications designed to suppress your immune response. These can work in many different ways with some targeting a broad range of immune cells and others being highly specific. These medications are often used for organ transplant recipients and people with moderate-severe autoimmune diseases. Some medications in this category include: organ transplant medications, biologics, and high dose corticosteroids
Chemotherapy- Chemotherapy often comes with the effect of preventing new fast-dividing cells from being produced. This is why hair loss is such a common side effect of chemotherapy. Immune cells are fast dividing and therefore frequently are unable to be produced while on chemotherapy
The effects of immunocompromisation
Immunocompromisation has a large range of effects depending on the reason someone is immunocompromised. The most common effects are an increased susceptibility to illness and cancers. Increased susceptibility to illness can look like:
Frequent illnesses
Illnesses that are more severe than they would be for other people
Recurrent infections
Infections that don't respond to medication
Delayed response to infection
Infections that last longer than usual
Some people are more susceptible to certain types of infections. For example anifrolumab, a biologic used for lupus, makes people more susceptible to herpes zoster and respiratory tract infections while prednisone, a corticosteroid, increases risk of infection across the board. This occurs due to different causes of immunocompromisation affecting different immune cells with different roles in preventing and responding to infection.
Grades of severity
Recently the term "moderately and severely immunocompromised" has been used in covid-19 resources. Certain factors are considered to make someone moderately or severely immunocompromised, these include:
Advanced or untreated HIV infection
Moderate or severe primary immunodeficiencies
Hematologic malignancies
Active treatment for solid tumors or hematologic malignancies
Immunosuppressant medications used for solid organ or islet transplants
CAR-T cell therapy or hematopoietic stem cell transplantation
Treatment with alkylating agents, antimetabolites, high-dose corticosteroids, chemotherapeutic agents, TNF blockers, and other biologic agents that are immunosuppressive or immunomodulatory
What immunocompromisation is not
It's worth noting that getting sick frequently or getting seriously sick from illnesses that are usually mild is a warning sign for being immunocompromised but does not inherently make you immunocompromised. Some people are just more susceptible to illness without being immunocompromised.
Having minimal response to an infection that is usually more serious is a sign of a strong immune system, not a weak one.
Being immunocompromised is also not the same as being high risk for serious infection. All immunocompromised people are high risk but not all high risk people are immunocompromised. Immunocompromisation is specifically when someone is high risk because their immune system is weak. Particularly in regards to covid, there are many conditions that make you higher risk that do not involve a weak immune system.
Autoimmune diseases do not automatically make you immunocompromised. Something being a disorder of the immune system does not mean that you are immunocompromised because immunocompromised means a weaker immune system not a malfunctioning immune system.
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