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#Yoshiro Kato
dare-g · 11 months
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The Deserted Archipelago (1969)
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byneddiedingo · 11 months
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Kyoko Kagawa and Toshiro Mifune in High and Low (Akira Kurosawa, 1963)
Cast: Toshiro Mifune, Tatsuya Nakadai, Kyoko Kagawa, Tatsuya Mihashi, Kenjiro Ishiyama, Isao Kimura, Takeshi Kato, Yutaka Sada, Tsutomu Yamazaki, Takashi Shimura. Screenplay: Hideo Oguni, Ryuzo Kikushima, Eijiro Hisaita, Akira Kurosawa. Cinematography: Asakazo Nakai, Takao Saito. Production design: Yoshiro Muraki. Music: Masaru Sato.  
High and Low begins surprisingly, considering that Kurosawa is known as a master director of action, with a long static sequence that takes place in one set: the living room of the home of Kingo Gondo (Toshiro Mifune), an executive with a company called National Shoe. The sequence, almost like a filmed play, depicts Gondo's meeting with the other executives of the company, who are trying to take it over, believing that the "Old Man" who runs it is out of touch with the shoe market. Gondo, however, thinks the company should focus on well-made, stylish shoes rather than the flimsy but fashionable ones the others are promoting. After the others have gone, we see that Gondo has his own plan to take over the company with a leveraged buyout -- he has mortgaged everything he has, included the opulent modern house in which the scene takes place. But suddenly he receives word that his son has been kidnapped and the ransom will take every cent that he has. Naturally, he plans to give in to the kidnappers' demands -- until he learns that they have mistakenly kidnapped the wrong child: the son of his chauffeur, Aoki (Yutaka Sada). Should he go through with his plans to ransom the boy, even though it will wipe him out? Enter the police, under the leadership of Chief Detective Tokura (Tatsuya Nakadai), and the scene becomes a complicated moral dilemma. Thus far, Kurosawa has kept things stagey, posing the group of detectives, Gondo, his wife (Kyoko Kagawa), his secretary (Tatsuya Mihashi), and the chauffeur in various permutations and combinations on the Tohoscope widescreen. But once a decision is reached -- to pay the ransom and pursue the kidnappers -- Kurosawa breaks free from the confinement of Gondo's house and gives us a thrilling manhunt, the more thrilling because of the claustrophobic opening segment. The original title in Japanese can mean "heaven and hell" as well as "high and low," and once we move away from Gondo's living room we see that his house sits high on a hill overlooking the slums where the kidnapper (Tsutomu Yamazaki) lives, and from which he can peer into Gondo's house through binoculars. We return to the police procedural world of Stray Dog (Kurosawa, 1949), where sweaty detectives track the kidnapper through busy nightclubs and the haunts of drug addicts, and Kurosawa's cameras -- under the direction of Asakazu Nakai and Takao Saito -- give us every sordid glimpse. It's a skillful thriller, based on one of Evan Hunter's novels written under the "Ed McBain" pseudonym, done with a masterly hand. Even though it's one of Kurosawa's lesser-known films, there are those who think it's his masterpiece. In any cast it has unexpected moral depth, enhanced by fine performances, including a restrained one by Mifune -- this time, the freakout scene goes to Yamazaki as the kidnapper.
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chinasub · 10 months
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在线观看遥远的地方 2023 完整版中文字幕-1080p
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在线观看遥远的地方 2023 完整版中文字幕
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在线观看遥远的地方 2023 完整版中文字幕 - Hello, readers of chinese muvie, Welcome and thank you for visiting our site. In this post with the title 在线观看遥远的地方 2023 完整版中文字幕, we have made and prepared it as best as possible so that all readers can easily understand the contents of this post. We hope that the contents in the 剧情 category, which we write, can be more easily understood by you and useful for you all. Alright, happy reading.
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Films about the Bakumatsu
Yajikita son'no no maki / Yaji and Kita: Yasuda's Rescue (Tomiyasu Ikeda, 1927) [Movie] Yajikita toba fushimi no maki / Yaji and Kita: The Battle of Toba Fusumi (Tomiyasu Ikeda, 1928) [Movie] Horo Zanmai / Wanderlust / The wandering Gambler (Hiroshi Inagaki, 1928) [Movie] Sakamoto Ryoma (Edamasa Yoshiro, 1928) [Movie] Kurama Tengu (Teppei Yamaguchi, 1928) [Movie] Kurama tengu: Kyofu jidai (Teppei Yamaguchi, 1928) [Movie] Roningai daiichiwa / Samurai Town, Story 1 (Masahiro Makino, 1928) [Movie] Roningai dainiwa / Samurai Town, Story 2 (Masahiro Makino, 1929) [Movie] Kurama Tengu: Ougon Jigoku (Daisuke Ito, 1942) [Movie ] Kurama Tengu: Kakubei Jishi (1951) [Movie] Kurama Tengu: Kurama no Himatsuri (1951) [Movie] Kurama Tengu Kaijo (1952) [Movie] Tsukigata Hanpeita (1952) [Movie] Isami Kondo Ikedaya Sodo (1953) [Movie]
Abare-jishi (Tatsuo Osone, 1953) Hana no Byakkotai / The Great White Tiger Platoon (Katsuhiko Tasaka, 1954) [Movie] Kurama Tengu: Shippu Happyaku Yacho (1954) [Movie] Gozonji Kaiketsu Kurozukin Maguna no Hitomi / The Black Hooded Man (Kiyoshi Saeki, 1955) [Movie] Gozonji Kurozukin Dai-Niwa Shinsengumi Tsuigeki / The Black Hooded Man (Kokichi Uchide, 1955) [Movie] Kurama Tengu: Goyoto Ihen (1956) [Movie] Shippu Kurama Tengu (1956) [Movie] Tsukigata Hanpeita: Hana no maki; Arashi no maki (Teinosuke Kinugasa, 1956) [Movie] Bakumatsu Taiyoden / Sun in the Last Days of the Shogunate (Yuzo Kawashima, 1957) [Movie] Kogoro Katsura to Isami Kondo Ryuko no Kessen (1957) [Movie] Ronin-gai (Masahiro Makino, 1957) [Movie] Shinsengumi (Yasushi Sasaki 1958) [Movie] Utamatsuri Kanzashi Matoi / Girl with the fire Banner (Kinnosuke Fukuda, 1958) [Movie] Kurama Tengu / Kurama Tengu: Goblin in Stirrus (Masahiro Makino, 1959) [Movie] Daibosatsu toge / Souls in the Moonlight 1 -3 (trilogy) (Tomu Uchida, 1957-1959) [Movies] Daibosatsu toge 1-3 (trilogy) (Kenji Misumi, 1959-1961) [Movies] Soretsu Shinsengumi: Bakumatsu no Doran / Shinsengumi: Last days of the Shogunate ( Ko Sasaki, 1960) [Movie] Tsukigata Hanpeita / Mask of the Moon (Masahiro Makino, 1961) [Movie] Ishin no Kagaribi / Bontires of the Restoration (Sadatsugu Matsuda, 1961) [Movie] Nagawakizashi (nagadosu) chushingura (Kunio Watanabe, 1962) [Movie] Shinsengumi Shimatsuki / Shinsengumi Chronicles (Kenji Misumi, 1963) [Movie] Zashets River / Washes Away the Moon (Yasushi Sasaki, 1963) [Movie] Hana no Shogai ep. 1 (1963) [taiga-drama, NHK] Bakumatsu zankoku monogatari / Brutal Story at End of the Tokugawa Shogunate (Tai Kato, 1964) [Movie] Ansatsu / The Assassination (Masahiro Shinoda, 1964) [Movie] Shin Kurama Tengu (Kimiyoshi Yasuda, 1965) [Movie] Shin Kurama Tengu, Gojozaka no Ketto (Yoshiyuki Kuroda, 1965) [Movie] Shinsengumi Keppuroku ep.1-26 (1965) ) [TV-serial, Asahi] Samurai / Samurai Assassin (Kihachi Okamoto, 1965) [Movie] Moeyo Ken / The Blazing Sword (Hirokazu Ichimura, 1966) [Movie] Daibosatsu toge / The Sword of Doom (Kihachi Okamoto, 1966) [Movie] Yojimbo (ep.1, 2,3,10,22 (from26)) (1967) [TV-serial, Asahi] Ryoma ga Yuku (1968) (ep.16 (from43)) [taiga-drama, NHK] Akage / Red Lion (Kihachi Okamoto, 1969) [Movie] Hitokiri / Tenchu! (Hideo Gosha, 1969) [Movie] Tengu-to / Blood End (Satsuo Yamamoto, 1969) [Movie] Shinsengumi / Band of Assassins / Assassins of Honor (Tadashi Sawashima, 1969) [Movie] Moeyo Ken (1970) (ep. 1,2,11,12 (from26)) [TV serial, Asahi] Bakumatsu / The Ambitious (Daisuke Ito, 1970) [Movie] Shinsengumi Noroi no Chisibuki (ep. 9 (from10 of Kaidan Series - Otoko no Maki)) (Nobuo Nakagawa, 1972) [TV serial] Okita Soji (Masanobu Deme, 1974) [Movie] Okami yo rakujitsu o kire / The Last Samurai ( Kenji Misumi, 1974) [Movie] Ryoma ansatsu (Kazuo Kuroki, 1974) [Movie] Kurama Tengu / Hooded Avenger ep.1-26 (1974) [TV-serial] Kurayami Shiokinin (Hissatssu, Season - 4) ep.1- 27 (1974) [TV-serial] Tokkan (Kihachi Okamoto, 1975) [Movie] Hissatsu Karakurinin Keppu Hen (Hissatsu, Season -) ep.1-11 (1976-77) [TV-serial] Kashin (1977) [taiga -drama (mini-serial), NHK] Shinsengumi shimatsuki (1977) (ep.26 (from 26)) [TV-serial, TBS] Shishi no Jidai (epp.1-51) (1980) [taiga-drama, NHK ] Kirisute Gomen (in ep.19-th (from Season 1, episodes 1a, 1b-25)) (1980) [TV serial] Kaiketsu Kurozukin / The Black Hood (Akikazu Ota, 1981) [Movie] Eijanaika / Why Not? (Shohei Imamura, 1981) [Movie] Kamata koshin-kyoku / Fall Guy (Kinji Fukasaku, 1982) [Movie] Ryoma ga Yuku (pert 1-5) (1982) [Tokyo TV, serial] Bakumatsu seishun graffiti: Ronin Sakamoto Ryoma (Yoshitaka Kawai, 1982) [NTN TV] [TV-film] Kita no hotaru / Fireflies in the North (Hideo Gosha, 1984) [Movie] Hissatsu! Brown kan no kaibutsutachi (Joo Hirose, 1985) [Movie] Kage no Gundan IV (Bakumatsu Hen) / Shadow Warriors IV (episodes 28-40) (1985) [Fuji TV, TV-serial] Bakumatsu seishun graffiti: Fukuzawa Yukichi (Yoshitaka (Yoshitaka Kawai, 1985) [TBS TV] [TV-film] Bakumatsu seishun graffiti: Ronin Sakamoto Ryoma (Yoshitaka Kawai, 1986) [Tokyo TV] [TV-film] Byakkotai (part 1-2) (Saito Takeichi, 1986) [NTV, TV-film] Shinsengumi (part 1-2) ( Yuichi Harada & Toshio Masuda, 1986) [Movie] Jazz Daimyo (Kihachi Okamoto, 1986) [Movie] Hara Sakata (part 1-2) (Saito Takeichi, 1987) [NTV, TV-film] Ryoma wo kitta otoko (Kosaku Yamashita , 1987) [Movie] Goryokaku (1988) [TV-serial, NTV] Ryoma Sakamoto (Part 1-2) (1989) [TV-film, TBS] Kiheitai (Part 1-2) (1989) [TV-film] Oabare Shigotonin! Yokohama ijin Yashiki no Ketto (Matsuno Kouki, 1990) [TV Special] Seizoroi Shigotonin! Harusame ja, Akunin Taiji (Shigeru Ishihara, 1990) [TV Special] Ronin-gai (Kazuo Kuroki, 1990) [Movie] Moeyo Ken (Part 1-2) (Yamamoto Kazuo, 1990) [TV-film] Tobu ga Gotoku (1990) [taiga-drama, NHK] Katsu Kaishu (Part 1-2) (1990) [TV-film] Fukuzawa Yukichi / The Passage to Japan (Shinichiro Sawai, 1991) [Movie] Ryoma ni Omakase! (1991) (ep.1-12) [TV-serial, NTV] Hono no gotoku Yoshida Shoin (Yoshida Shoin en no gotoku) (Hiroki Shuzen, 1991) [TV film, NTV] East Meets West (Kihachi Okamoto, 1995) [Movie] Kita no zeronen / Year One in the North (Isao Yukisada, 1995) [Movie] Gokenin Zankuro (Sesons 1-5) (1995-2002) [TV-serial, Fuji TV] Ryoma ga yuku / Ryoma Forever (part 1.2) (Tokizo Wakita, 1997) [TV film, TBS] Genma Sappocho: Shinsengumi Hishou / Kunoichi: Deadly Mirage (Akiyama Yutaka, 1997) [Movie] The Spirit of the Samurai / Fascination II (Takarazuka, Star Troupe, 1997) Shinsengumi Keppuroku / Shinsengumi: The Shogun's Defense (Eiichi Kudo, 1998) (ep.1-10) [TV-serial] Gohatto / Taboo (Nagisa Oshima, 1999 ) [Movie] Shinsengumi - Na mo naki Otokotachi no Souwa (2002) [Theater-Play] Souten no yume Shoin to Shinsaku shin-seiki eno chosen (2002) [TV NHK] Ryoma no tsuma to sono otto to aijin (Jun Ichikawa, 2002) [Movie] Mibugishiden Sinsen-gumi de ichiban tsuyokatta otoko (Part 1-4) (2002) [TV-miniserial] Mibu gishi den / When the Last Sword Is Drawn (Yojiro Takita, 2003) [Movie] Ooku / Oh- oku (Season 3, ep 1-12) (2003) [TV-serial, Fuji TV] Yami Musha / Dark Warrior (Hitoshi Ozawa, 2004) [Movie] Roningai / The Street of Masterless Samurai (part 1-2) (2004) [Theater Play] Izo: Kaosu mataha fujori no kijin / Izo (Takashi Miike, 2004) [Movie] Ryoma ga Yuku (part 1-4) (2004) [TV-mini serial] Kusa no ran / Grassroot Rebellion (Seijiro Koyama, 2004) [Movie] Shinsengumi! (2004) (ep.1-49) [NHK taiga drama] Otokotachi no Kyo / Samurai Mad Fellows (Joy Ishii, 2005) [Movie] Shinsengumi !! Hijikata Toshizo saigo no ichi-nichi (Kunio Yoshikawa, 2006) [TV-Special] Chosyu Five (Sho Igarashi, 2006) [Movie] Jitsuroku Sehinsengumi (Hiroyuki Tsuji, 2006) [Movie] Jitsuroku Shinsengumi Kanketsu hen (2006) Tsroy [Movie] Tsukigami / The Haunted Samurai (Yasuo Furuhata, 2007) [Movie] Wachigaiya Itosato: Onna-tachi no Shinsengumi (part 1-2) (2007) [TV-film, TBS] Byakkotai (part 1-2) (2007) [TV-film] Man of Stardust (Starlight) / Joyful !! II (Takarazuka, Snow Troupe, 2007) Atsuhime (ep. 1-50) (2008) [taiga-drama, NHK] Kurama Tengu (ep. 1-8) (2008) [TV-serial, NHK] Shinkansen Produce Inoue Kabuki- Izo (part 1-2) (2008) [Theatrical Play] Bodi jakku / Body Jack (Yoshio Kuratani, 2008) [Movie] Jin (2009) (ep. 1-11 + SP) [TV serial] Ryoma den (ep. 1-40 (from 49) + 2SP) (2010) [taiga-drama, NHK] Shinsengumi PEACE MAKER (ep.1-5 + SP) (2010) [TV-serial, TBS]
Foreign movies: Yoshiwara (Max Ophus, 1937) [Movie] The Barbarian and the Geisha (John Huston, 1958) [Movie] The Bushido Blade (Tsugunobu Kotani, 1981) [Movie] The Last Samurai (Edward Zwick, 2003) [Movie]
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phgq · 3 years
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Japan says vaccination not required for Olympics
#PHnews: Japan says vaccination not required for Olympics
ANKARA – Japan on Tuesday said vaccination is not a requirement for participating this July-September in the Olympic Games, which were delayed last year due to the pandemic.
“We are considering comprehensive measures to hold safe and secure games, even without making vaccines a condition,” Katsunobu Kato, the chief Cabinet secretary of the Japanese government, told a news conference.
Japan was set to host the Olympics last year but the world’s biggest games were delayed due to the Covid-19 pandemic.
The government of Prime Minister Yoshihide Suga is adamant to go ahead with the Olympics and Paralympics this year to be held from late July through early September.
A survey conducted by Kyodo News found at least 80 percent of respondents seeking rescheduling of the games.
Last week, the head of the Tokyo Olympics organizing committee said it is “absolutely impossible” to postpone this year’s Summer Olympics even amid the novel coronavirus.
“Having even a slight sense of uncertainty impacts everything. All I can say is that we will go ahead with our preparations,” Yoshiro Mori said.
The Tokyo Olympics is estimated to cost USD15.8 billion.
Infections rising
In recent months, Japan has witnessed surges in Covid-19 infections, mostly in the capital Tokyo, where the games are scheduled to be held.
Suga's government imposed a state of emergency once again in several provinces to allow central and local authorities to handle the pandemic.
Tokyo reported 1,240 new infections of the coronavirus on Tuesday -- over 1,000 cases for the seventh consecutive day -- while the tally hit 87,914 in the capital.
The government plans to begin vaccinations by late February starting with medical workers and elderly people.
“I will do everything in my power to ensure safe and effective vaccines can be given to as many people as possible, as quickly as possible,” said Taro Kono, who was appointed on Monday to lead Japan’s battle against the coronavirus.
He is also holding serving as the administrative reform minister in Suga’s Cabinet.
Japan has signed agreements with Pfizer, AstraZeneca, and Moderna to receive vaccines for its people by the first half of this year.
The country has seen 335,795 infections, including at least 4,370 deaths, according to the US-based John Hopkins University. (Anadolu)
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References:
* Philippine News Agency. "Japan says vaccination not required for Olympics." Philippine News Agency. https://www.pna.gov.ph/articles/1127904 (accessed January 20, 2021 at 05:13AM UTC+14).
* Philippine News Agency. "Japan says vaccination not required for Olympics." Archive Today. https://archive.ph/?run=1&url=https://www.pna.gov.ph/articles/1127904 (archived).
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kasico · 4 years
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「桑田佳祐 & The Pin Boys / 悲しきプロボウラー」Music Video
Director: KASICO Assistant Director: Takko Yoshida Producer: Hitoshi Sugai, Fumiko Iino Production Manager: Tatsuru Ishiwata, Shogo Minowa Yusei Takada, Yuko Ueno, Yuki Shiina Director of Photography, Shosuke Fukudome, Tomohiko Takeno 1st Camera Assistant, Ko Miura Lighting Director, Saki Iida 1st Assistant Lighting, Shinkichi Komatsu 2nd Assistant Lighting, Akito Saito, Hidehiko Kato Hideetsu Ota, Chizuru Koga, Kairi Nakamura Art Designer: Kanako Nakazato Art Assistant: Chizuko Ishii, Yuuka Mogi, Tatsuya Imai Casting: Ami Sakamaki, Jun Hasebe, Yoshimi Takashima, Anna Yoshida Stylist: Yohei “yoppy” Yoshida Cast Stylist: Akemi Muraki Cast Hair & Make Up: URI, Aki Yasuda, Masamitsu Sakai Choreography: Anna Yoshida Driver: Ryuhei Sakamoto, Yoshifumi Moriya, Satoru Nojima Color Grading: Yoshiro Kamei Composite: Hiroyuki Sai, Kenji Sakaide Location: Enoshima Bowl, Shonan Fujisawa Film Commission
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scitechnetwork · 7 years
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Potential drug for treating chronic pain with few side effects
Provided by: Okayama University
Researchers  at  Okayama  University  describe  in Proceedings  of  the National  Academy  of  Sciences  the  effect  of  clodronate  on  the  regulation  of  adenosine triphosphate  release  and  its  potential  as  a  drug  for  the  treatment  of  chronic  pain.    The compound  has  few  side  effects  and  may  also  be  effective  for treating  other  medical conditions including diabetes.
Typical  drugs  for  treating  chronic  pain —  a  condition  estimated  to  affect  20 –  25%  of  the world͛s  population —  often  cause  serious  side  effects  such  as  stomach  problems,  kidney failure  or  addiction.    Now,  a  team  of  researchers  led  by  Yuri  Kato  and  Takaaki  Miyaji  from Okayama  University  has  identified  a  compound,  clodronate,  that  inhibits  the  mechanism triggering chronic pain while having few side effects.  Clodronate may therefore be used for future  chronic  pain  drug  development.    Moreover,  the  researchers reckon  it  may  also  be effective for the treatment of other diseases such as diabetes and neurological disorders.  Acute  pain  is  the  result  of  sensory  nerves  responding  to  a  (potentially)  harmful  stimulus,  a biological  process  called  nociception.    However,  inflammation  or  nerve  injuries  can  trigger pathological   nociception —   a   long-lasting   sensation   of   pain   due   to   the   stimulated production  of  adenosine  triphosphate  (ATP)  molecules  that  bind to  so-called  purinergic receptors  causing  pain  responses.    The  ATP  molecules  participating  in  the  purinergic signalling processes are carried by vesicular nucleotide transporter (VNUT) protein.  Since it is known that suppression of  VNUT function  leads to an improvement of neuropathological conditions  in  mice,  Moriyama  and  Miyaji  and  colleagues  looked for  a  VNUT  inhibitor  with few side effects. The  researchers  tested  clodronate,  a  molecule  belonging  to  the  class  of  bisphosphonates, compounds  used  for  treating  osteoporosis.    Clodronate  does  not  contain  nitrogen,  a characteristic known to decrease therapeutic effect for osteoporosis and the number of side effects.    Experiments  on  proteoliposomes  showed  that  clodronate  is a  potent  inhibitor  of VNUT, whereas injections of clodronate in wild-type mice showed that it attenuated chronic neuropathic and inflammatory pain. The scientists confirmed that clodronate has few side effects, and noted that its therapeutic effectiveness   is   stronger   than   that   of   other   widespread   drugs   for   neuropathic   pain.  Clodronate͛s  potent  inhibition  of  VNUT  also  makes  it  a  highly  relevant  candidate  drug  for the treatment of diabetic symptoms.  Given that  clodronate  is currently clinically approved in   many   countries   for   the   treatment   of   osteoporosis,   the   drug   has   great   potential.  Accordingly,  Kato  and  Miyaji  and  colleagues  conclude  their  report  by  noting  that further studies  regarding  the  wide  range  of  applications  of  clodronate  are  currently  in  progress  in our laboratories.͟ 
Background 
Chronic pain 
In  medicine,  pain  lasting  a  long  time —  typically,  3  months  or  more —  is  called  chronic,  as opposed  to  acute  pain.    Chronic  pain  can  be  neuropathic, when  the  nervous  system  is damaged,  or  nociceptive,  when  inflammation  causes  nociceptors  (pain  sensors)  to  be triggered permanently. Current drugs for the treatment of chronic pain, notably opioids like morphine, have various side  effects,  including  stomach  or  kidney  dysfunction,  drug addiction,  drowsiness  and vomiting.  Yuri Kato and Takaaki Miyaji and colleagues have now identified a potential non-opioid drug, clodronate, that suppresses chronic pain by inhibiting the release of adenosine triphosphate (ATP), a mechanism involved in chronic pain. 
Purinergic signalling 
In  living  organisms,  purinergic  signalling  is  a  way  of  passing  on  signals  outside  cells.    It involves  purines,  particular  types  of  aromatic  molecules  containing  nitrogen,  and  so-called purinergic  receptors  in  cells.    The  purinergic  signalling  mechanism  associated  with  chronic pain involves the purine adenosine triphosphate (ATP), a molecule playing an important role in  biological  energy  transfer  processes;  ATP  is  carried  by  vesicular  nucleotide  transporter (VNUT)  protein.    The  present  study  shows  that  clodronate  inhibits  VNUT,  which  in  turn attenuates  neuropathic  and  nociceptive  pain.    Since  clodronate has  few  side  effects  and since it has already been clinically approved in many countries, it is a promising drug for the treatment of chronic pain.
Reference:
Yuri  Kato,  Miki  Hiasa,  Reiko  Ichikawa,  Nao  Hasuzawa,  Atsushi  Kadowaki,  Ken  Iwatsuki, Kazuhiro  Shima,  Yasuo  Endo,  Yoshiro  Kitahara,  Tsuyoshi  Inoue,  Masatoshi  Nomura,  Hiroshi Omote,  Yoshinori  Moriyama  &  Takaaki  Miyaji.  Identification  of  a  vesicular  ATP  release inhibitor  for  the  treatment  of  neuropathic  and  inflammatory  pain. Proceedings  of  the National Academy of Sciences, Month Day, 2017. DOI: 10.1073/pnas.1704847114.
https://www.ncbi.nlm.nih.gov/pubmed/28720702
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Clodronate-evoked  inhibition  of  vesicular  ATP  release  is  important  for  the  treatment  of chronic pain.
Provided by: Okayama University
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grahanusantaracoid · 4 years
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Olimpiade Tokyo 2020 Resmi Ditunda
Graha Nusantara – Perdana Menteri Jepang, Shinzo Abe, dan Presiden Komite Olimpiade Internasional (IOC), Thomas Bach, sepakat menangguhkan gelaran itu sampai 2021 karena virus corona, Selasa (24/3/2020) malam hari WIB.
Panitia penyelenggara Olimpiade tersebut  masih mengatakan acara itu akan digelar sesuai yang telah dijadwalkan, akhir Juli 2020. Tetapi, keputusan tersebut berubah oleh panitia…
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ibomleak · 4 years
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Tokyo 2020 Olympic Committee admits postponement realistic option
Tokyo 2020 Olympic Committee admits postponement realistic option WORLD NEWS! South Korea reports lowest number of new cases read more >>>
Yoshiro Mori, President of the Tokyo 2020 Olympic Games Organising Committee, reacts as he attends a news conference in Tokyo, Japan March 23, 2020. REUTERS/Issei Kato
TOKYO (Reuters) – After weeks of insisting that the Tokyo 2020 Olympics would go ahead as planned despite the novel coronavirus becoming a global pandemic, the organizing committee admitted on Monday that postponement…
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yeskraim · 4 years
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China coronavirus outbreak: All the latest updates
China on Thursday removed the top political leadership in Hubei, the province at the centre of the escalating coroanvirus outbreak, shortly after health officials there reported 242 people died from the virus on Wednesday – more than twice the number of the previous day and the highest daily toll since the outbreak began.
The province and its capital Wuhan where the infection now known as COVID-19 is thought to have originated in late December also reported more than 14,800 new cases of the infection after adopting new clinical methods to diagnose the virus.
The number of infected across China rose to nearly 60,000.
More:
In Hong Kong, new virus rekindles old animosities towards China
COVID-19: WHO renames deadly coronavirus
Weakest link: Global supply chains disrupted by coronavirus
At least 25 countries have confirmed cases and several nations have evacuated their citizens from Hubei. Two deaths have been recorded outside mainland China – one in  Hong Kong and one in the Philippines.
The World Health Organization (WHO) has warned the virus poses a “grave threat” to the world, with chief Tedros Adhanom Ghebreyesus, saying the virus could have “more powerful consequences than any terrorist action”.
Here are the latest updates:
Thursday, February 13
Official media have reported that a commune of 10,000 residents northwest of the capital Hanoi was put in lockdown due to a cluster of cases there.
The online newspaper VN Express cited a senior official of Vinh Phuc province as reporting an increase in cases in Son Loi commune.
Vietnam has confirmed 16 case of the diseases, most of them in the province.
Researchers ramp up efforts to develop coronavirus vaccine
North Korea imposes quarantine measures on all foreign visitors
North Korea will impose a month-long quarantine on all foreign visitors and others suspected to have COVID-19, the official Korean Central News Agency said on Thursday.
The decision to extend the quarantine period to 30 days was based on research studies suggesting the incubation period of the virus could be as long as 24 days.
The report did not confirm the country’s previous quarantine period, but the Russian Embassy in Pyongyang said in a Facebook post earlier this month that North Korea was putting foreign visitors under a 15-day quarantine.
North Korea has yet to report a case of the virus, but state media reports have hinted that an uncertain number of people have been quarantined after showing symptoms.
China replaces head of its Hong Kong and Macau affairs office
China is replacing the head of its office that oversees matters in Hong Kong, the human resources ministry announced in Beijing on Thursday.
Xia Baolong, a 67-year-old vice chairman of the Chinese People’s Political Consultative Conference (CPPCC), will replace Zhang Xiaoming. 
Communist party chief in Wuhan replaced – state media
Ma Guoqiang, the party chief in Hubei’s capital Wuhan, has been fired, the state-run Global Times reported.
The paper said the removal of the provincial bosses amid complaints over their handling of the outbreak showed the central government was responding swiftly to the crisis.
Here is a significant sign of how swiftly China’s central govt responds to the #coronavirus outbreak: it took only about 2 months to see a major reshuffle of top officials in #coronavirus epicenter Hubei compared to 4 months during the 2003 #SARS outbreak. https://t.co/00N9bpNN69 https://t.co/gUyFBzZPQF pic.twitter.com/crRD2UMHso
— Global Times (@globaltimesnews) February 13, 2020
Singapore official warns more coronavirus cases likely
An official in Singapore official said the number of infections in the city-state was likely to rise because the virus was clearly circulating within the population.
“We really cannot say whether it will get better, whether it will get worse, what sort of situation is going to unfold,” Lawrence Wong, a co-chairman of Singapore’s task force fighting the outbreak, said.
“We don’t know how successful we will be in all of these containment measures that we have put in place.” 
Wong said additional measures could involve “social distancing in order to try and reduce the chance of the virus spreading further.”
Singapore has reported 50 confirmed cases. Eight people are in criticial condition, while 15 have fully recovered. 
China’s Hubei province communist party chief relieved of duty – state media
Jiang Chaoliang, the head of the Communist Party in the Chinese province of Hubei, the epicentre of the coronavirus outbreak, has been relieved of his duties, state media reported on Thursday.
Shanghai Mayor Ying Yong has been appointed as the new secretary of the Hubei Provincial Committee of the Communist Party of China, the report said, citing the party’s central committee
44 more coronavirus cases on Japan ship: health minister
A further 44 people on board a cruise ship moored off Japan’s coast have tested positive for the novel coronavirus, the country’s health minister said on Thursday.
Health Minister Katsunobu Kato said the 44 new cases were detected from another 221 new tests. They raise the number of infections detected on the Diamond Princess to 218, in addition to a quarantine officer who also tested positive for the virus.
More people on board the quarantined Diamond Princess were diagnosed with COVID-19 on Thursday [Kim Kyung-Hoon/Reuters]
Tokyo, IOC officials reiterate that the Olympics are on
Tokyo Olympic organisers reiterated on Thursday at the start of two days of meetings with the International Olympic Committee: the Summer Games will not be waylaid by the coronavirus that is spreading from neighbouring China.
“I would like to make it clear again that we are not considering a cancellation or postponement of the games. Let me make that clear,” Yoshiro Mori, the president of the organising committee, said, speaking through an interpreter to dozens of top IOC officials gathered in Tokyo.
The Olympics open in just over five months, and the torch relay begins next month.
Numerous sporting events have already been postponed as a result of the virus. 
Seriously ill pushed to margins as China battles coronavirus
Ruyi Wan was diagnosed with leukaemia last May and was hoping for a bone marrow transplant after chemotherapy failed.
But as medical resources are funnelled into fighting the coronavirus, the 20-year-old has been unable to get treatment in Wuhan and cannot go elsewhere because of the travel restrictions. With a serious illness she is also more vulnerable to the infection.
“I hope for a miracle because Ruyi is so young and has so many dreams,” her mother Juan Wan told Al Jazeera. “We can’t let her die.”
Read Shawn Yuan’s story on the people suffering from cancer, kidney disease and HIV now struggling to get the treatment they need in a system stretched to its limits.
US airlines extend China flight cancellations into late April
United Airlines said late on Wednesday it would extend cancellations of all US flights to China until late April because of the coronavirus, joining other US carriers that have suspended China routes.
Airlines say part of the reason is a dramatic drop-off in demand, but the US has also introduced strict restrictions on travellers to the United States who have visited China, barring nearly all non-US residents if they have been in China within the previous14 days.
The US is also limiting flights from China or other international flights with US passengers who have been to China within the previous 14 days to 11 major airports for enhanced screening. It also requires a quarantine of US citizens who have recently visited Hubei province in China.
As we continue to evaluate our operation between our U.S. hubs and Beijing, Chengdu, Shanghai and Hong Kong, we have decided to extend the suspension of those flights until April 24. Learn more: https://t.co/3g6Lbe4xQZ pic.twitter.com/IabHFdcYmP
— United Airlines (@united) February 13, 2020
CDC confirms 14th US case of coronavirus in Wuhan evacuee
A second person evacuated from Wuhan to a US military base near San Diego has been diagnosed with the new coronavirus, raising the tally of confirmed cases in the United States to 14, the Centers for Disease Control and Prevention (CDC) said on Wednesday.
The patient was among 232 people under quarantine at the Marine Corps Air Station Miramar after being airlifted out of Wuhan earlier this month, CDC spokeswoman Ana Toro said.
Another evacuee was diagnosed with the virus earlier this week, but CDC officials said it appeared the two had been separately exposed to the virus in China before arriving in the United States.
They arrived on different planes and were housed in separate facilities.
“At this time there is no indication of person-to-person spread of this virus at the quarantine facility, but CDC will carry out a thorough contact investigation as part of its current response strategy to detect and contain any cases of infection with this virus,” Dr Christopher Braden, deputy director of the CDC’s National Center for Emerging and Zoonotic Infectious Diseases, said in a statement.
Cruise ship shunned over coronavirus fears arrives in Cambodia – ship tracker
A cruise ship which had spent two weeks at sea after being turned away by five countries over fears that someone on board might have the coronavirus arrived in Cambodia on Thursday, satellite-tracking data showed.
The MS Westerdam arrived in Sihanoukville, according to data published by the Marine Traffic website.
Although no passengers have fallen ill on board, the ship had been turned away by Japan, Taiwan, Guam, the Philippines and Thailand over fears that someone on the cruise could have the virus.
UK confirms new case, first in London
The UK has confirmed its ninth case of coronavirus, saying the latest patient – the first in London – had caught the virus while in China.
“One further patient in England has tested positive for the novel coronavirus (COVID-19), bringing the total number of cases in the UK to nine,” Chris Whitty, chief medical officer for England said in a statement.
“This virus was passed on in China and the patient has now been transferred to a specialist NHS centre at Guy’s and St Thomas’ in London.”
Read more about which countries have confirmed cases here.
Read the updates from Wednesday, February 12 here.
Read More
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byneddiedingo · 1 year
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Toshiro Mifune and Tatsuya Nakadai in Samurai Rebellion (Masaki Kobayashi, 1967)
Cast: Toshiro Mifune, Yoko Tsukasa, Go Kato, Tatsuyoshi Ehara, Etsuko Ichihara, Isao Yamagata, Tatsuya Nakadai. Screenplay: Shinobu Hashimoto, based on a story by Yasuhiko Takiguchi. Cinematography: Kazuo Yamada. Production design: Yoshiro Muraki. Film editing: Hisashi Sagara. Music: Toru Takemitsu.
Like his Harakiri (1962), Masaki Kobayashi's Samurai Rebellion has a theatrical, almost Shakespearean quality and is sharply critical of the samurai code of honor. Toshiro Mifune plays Isaburo, a samurai whose son Yogoro (Go Kato) is ordered to marry the concubine Ichi (Yoko Tsukasa) of the daimyo of the clan he serves. Yogoro is reluctant, partly because Ichi has a son by the daimyo, but eventually they fall in love. Unfortunately, the daimyo's older son dies, making Ichi's child the heir, and she is ordered to return to his household. The ensuing rebellion against the daimyo's order proves calamitous to everyone. Beautifully committed performances heighten the story's tragic drive. The film's English title was apparently designed to persuade Western audiences that they were going to see a conventional samurai film, whereas it's really a story about the heroic self-sacrifice of Ichi, giving a feminist spin to the genre.
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