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a-panda-reads-act-omega · 7 years

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ACT OMEGA PART 22

THE 03/17/17 UPDATE

HERE WE GO, finally an update with a BUNCH of pages for me to comment about. Page 115-126, how exciting. God I need to get better with intro’s I’m sorry.

Heh, I like how everybody’s emotions are clear as day here. Anyways, nobody new’s here which makes me hope that this cast of characters will continue to interact and mingle.

W o ah there, calm yourself Vriska. She’s not lookin pleased with Tavvy over there. Also, I love how this is literally the exact same panel other than Vriska.

VRISKA: Wh8t?! VRISKA: The hell are all of you st8ring at???????? MEENAH: 38/

WHAT? IT’S PERFECTLY NORMAL TO PASS OUT DURING A LIFE-THREATENING BATTLE AGAINST AN UNKILLABLE GOD.

Fish gills changed a bit. This animation is also g re a t. I could literally watch Vriska just dust herself off for hours. God that sounded creepy. Fefefri is seeminnnn a lil taken aback here. And Meenah is real disappointed. Or just looking away to please Vriska, which would be cute but is probably not the case.

I love how not good Vriska is at recovering from embarrassing moments.

Oooohhh shit. Le’s behind the Juju im guessing, but that green hole is gettin closer and closer. They might need to start getting out of here soon.

VRISKA: What the hell just HAPPENED?

Homestuck happened. And you passed out.

Tavros raising his hand like a student. He would totally be the kind of student the teacher always has to pander to, even though the rest of the class is tired of hearing the same thing explained over and over.

TAVROS: dO YOU MEAN, tHE EXPLOSION,,,? TAVROS: oR,,, TAVROS: WAS IT AN ATTACK? TAVROS: iT WAS HARD TO TELL THE DIFFERENCE, TAVROS: sO MAYBE IT DOESN’T MATTER,,,

Was that explosion he’s talking about just the LE mouth blast? I think it’s an attack Tavros. Less of an explosion than it was a beam with boomy results.

VRISKA: Tavros, stop. VRISKA: Just, stop. Right now. I’m already twice over the limit of how much 8ullshit I can take in one day, and your irrit8ing voice is THIS close to giving me a head8che. TAVROS: uHHH,,,? VRISKA: Nope, too l8. Migr8ne city, popul8tion: me! Thanks a 8uttload, 8oy skylark. TAVROS: i,,,iM,,,sORRY,,,? DAVEPETASPRITE^2: B33 < yeah sorry about your head vwhiskers but i gotta interject here DAVEPETASPRITE^2: B33 < furst off your head hurts beclaws it got hit with a deadly fuckin laser pointer

Hahah. Get it? Laser pointer. Because. CAT. And also, holy shit Vriska got HIT with that?? Or was it just an explosion thingy FROM the laser pointer that knocked her out.

DAVEPETASPRITE^2: B33 < so blaming it on tavros f33ls purrty damn rude to me tbh DAVEPETASPRITE^2: B33 < but i dont really wanna get into a catfight with you right now DAVEPETASPRITE^2: B33 < or maybe not ever cause thats just like NOPE no thanks

You’re the best Davepeta. Almost as great as Vriska.

DAVEPETASPRITE^2: B33 < cranky vriska? ill pass on that DAVEPETASPRITE^2: B33 < especially since there are like DAVEPETASPRITE^2: B33 < way more important things to be dealing with! DAVEPETASPRITE^2: B33 < so ill let it slide fur now B33 DAVEPETASPRITE^2: B33 < as you were saying tavros?

So can Davepeta just be Tavros’ wingman? Because holy shit that’d be great. Actually, could this be the beginning of a beautiful PALE ROMANCE?? Probably not because ARquius is totally their soulmate.

TAVROS: wELL,,, tHANK YOU, fOR SPEAKING ON MY BEHALF, eVEN IF IT WASN’T STRICTLY NECESSARY,

It was necessary tavros.

TAVROS: uHHHH,,,

My point exactly.

TAVROS: bIRD NEPETA? TAVROS: oR, wHOEVER YOU ARE, DAVEPETASPRITE^2: B33 < youre half right! DAVEPETASPRITE^2: B33 < its davepeta TAVROS: oH, TAVROS: oKAY, TAVROS: sO,,,dAVEPETA,,, TAVROS: dO YOU THINK IT WAS AN ATTACK OR AN EXPLOSION? DAVEPETASPRITE^2: B33 < tavros DAVEPETASPRITE^2: B33 < are you holding onto your socks because im about to blow them the fuck off DAVEPETASPRITE^2: B33 < i think it was an attack DAVEPETASPRITE^2: B33 < that was ALSO an explosion DAVEPETASPRITE^2: B33 < >B33 TAVROS: }:o

:o MAN, Davepeta you need to chill! I have to go get dressed now, because you just blew my entire OUTFIT off! from shirt to shorts, nothing could withstan the sheer FORCE of your shocking observation.

VRISKA: UGH!!!!!!!!

Shut up Vriska.

Oh. We also got a Porrim back there. And, I guess that’s just Kankri? Maybe the same one, maybe a different? Vriska needs to chill though.

VRISKA: I don’t have TIME for this! VRISKA: Who gives a shit if it was an att8ck or WH8TEVER!!!!!!!! VRISKA: Am I the really only person who c8res about m8king sure the most evil fucker in all of paradox space is FINALLY DE8D FOR GOOD?!?!?!?! VRISKA: Isn’t that what we r8sed an entire army for?? VRISKA: The army that is NOWH8RE TO 8E FOUND, 8Y THE W8Y!!!!!!!!

I think they’re all d e a d Vriska. And you’re assuming way too much of this group of NINCOMPOOPS. They literally are just doing whatever.

MEENAH: vriska VRISKA: WH8T!!!!!!!! MEENAH: you need to krill out for a sec

Exactly. Krill out girl.

VRISKA: NO, *YOU* “KRILL OUT”!!!!!!!! VRISKA: I AM N8T GOING TO KRILL IN A SINGLE FUCKING DIRECTION UNTIL SOME8ODY DECIDES TO OPEN THEIR MOUTH AND FILL ME IN ON WH8T THE FUCK JUST HAPPENED!!!!!!!! MEENAH: the armys gone

Yup. Everybody fucking died via death laser.

FFS CHILL Vriska.

VRISKA: GONE?! VRISKA: No SHIT, they’re GONE! VRISKA: Do YOU see a throng of expenda8le, huddled masses anywh8re near8y, Meenah?? 8ecause if so, NOW WOULD 8E A GR8 TIME TO LET ME KNOW! MEENAH: ...

Calm down Vriska, before you push away the people that AREN’T dead. I mean, who know’s if these guys even care enough to keep working for you anyways. I’d say Meenah’s the last person you should be yelling at.

VRISKA: No?? That’s what I fucking THOUGHT. VRISKA: Th8nk you SO much for that astute o8serv8tion! VRISKA: That sure clears up JACK SQU8T! VRISKA: Now how a8out we get 8ack to the LESS immedi8tly o8vious! VRISKA: Gone WHERE? And more importantly, WHY! MEENAH: listen serks i could really do without the attitide MEENAH: if you took two seconds to breathe you could prolly figure it out yourself MEENAH: but if itll help you clam down...

Exactly, Clam down Vriska. Because it doesn’t take a goddamn genius to figure out they’re all dead.

VRISKA: It DEFIN8TELY will. So spill!!!!!!!! MEENAH: they got blasted VRISKA: Are you serious? VRISKA: He took out EVERYONE? In one hit?! MEENAH: nah not all of em MEENAH: but a lotta double death happened yeah MEENAH: i mean the weapon didnt do flip of what it was SUPPOS-ED to do as far as i could tell MEENAH: it did a pretty good job of sheildin our asses MEENAH: (youre whalecome btw)

Meenah, you’re the true hero here. I mean a calm troll who’s powerful, smart, and only sometimes out of order? I’d say that’s the best kinda troll we can get.

MEENAH: but anybody who didnt get behind it MEENAH: definitely got fried VRISKA: So? Where’s Lord English now?? VRISKA: 8ecause if we need to track him down, we need to get on that like, yesterday!

He isn’t still there? I thought he’d just be doing some angry lord english stuff. Hopefully he isn’t causing too much trouble.......

MEENAH: uh MEENAH: dudes still havin a tantrum over there actually

Oh. I was r i g h t .

VRISKA: Then why the hell are we all the w8y out here?! MEENAH: look vriska MEENAH: the plan didnt work MEENAH: you got KOd or passed out or whatever the shell MEENAH: and the army got gutted MEENAH: so i figured the only sensible fin to do was a tactical retreat VRISKA: Okay, fine. That WAS pretty sensi8le. MEENAH: except MEENAH: most of everyone didnt STOP retreatin MEENAH: no matter what inspirational crab i threw at them VRISKA: .......

Oh.

so there WERE more survivors, but the most’ve them just bailed on the scene. Damn. Well, who can blame them? Double death isn’t for everyone I suppose.

Well ARADIA sure seems happy :D

MEENAH: sorry aboat your head by the way MEENAH: ill admit that was my bad MEENAH: aint easy to haul ass in sand with dead weight over your shoulder

To the people behind ACT OMEGA: You better get me a gif of Meenah dragging Vriska face down through the sand.

ARADIA: hey! ARADIA: at least theres a bright side to all this

Of COURSE there is AA.

Awe. This team charge hug is actually kinda precious. Tavros’ little smile, and Aradia’s “appreciate him!” look.

ARADIA: tavros convinced a few people to stay ARADIA: right? :D

Oh, well that’s good then! So far, I know we have... Tavros, Aradia, Sollux, Kankri, Porrim, Mituna, Feferi, Latula, Vriska, Meenah, Davepeta, and possibly more.

TAVROS: i DID, TAVROS: tHROUGH THE POWER OF FRIENDSHIP,

TAVROS: aND A LARGE QUANTITY OF WORDS, sPOKEN DIRECTLY FROM THE HEART, TAVROS: eVEN THOUGH IT WOULD HAVE BEEN BETTER IF ALL OF THEM HAD STAYED, i THINK, TAVROS: tHERE IS A PART OF ME THAT ALSO THOUGHT LEAVING MIGHT HAVE BEEN A GOOD IDEA,,, TAVROS: cONSIDERING, hOW THINGS LOOK PRETTY HOPELESS NOW, TAVROS: bUT THAT PART OF ME IS THE ONE THAT MISSED OUT ON THE COMPLETION, oF MY SUCCESSFUL AND FULFILLING CHARACTER ARC,

He get’s so cocky sometimes, but it’s the kind of cocky where he’s nervous he’s not looking cocky in the right way. What the hell am I typing. I just love how self aware he is.

TAVROS: wHICH IS WHAT THE MAJORITY OF THE REST OF ME IS COMPRISED OF, TAVROS: eSPECIALLY THE PARTS THAT WERE KICKING LORD ENGLISH IN THE FACE, nOT TOO LONG AGO, TAVROS: aND TRUTHFULLY, i AM STILL PRETTY FIRED UP, fROM THAT, TAVROS: sO I IGNORED THE COWARDLY IMPULSE, aND INSTEAD STAYED TO HELP MY FRIENDS, sEE THIS UNDERTAKING THROUGH TO THE END, TAVROS: aND THERE WERE SOME PEOPLE, wHO AGREED WITH ME, TAVROS: wHICH ARE THE PEOPLE WHO ARE HERE, pRESENTLY,

Goddammit, these people aren’t the brightest. They had to have stayed with him out of pity. If all of your friends are running away, and the only person asking you to stay and fight an unkillable demon was T A V R O S .

You’d run.

Sollux doesn’t wanna be here.

ARADIA: see? sollux and i even stayed to help too ARADIA: in fact were all here to help ARADIA: well maybe some of us are here mostly out of curiosity SOLLUX: 0r b0red0m.

Or pity. Or self-hate. Or a deathwish.

ARADIA: or that too! or maybe even a mishmash of all sorts of motivations ARADIA: but whatever the reason we are on your side ARADIA: so i get the feeling if you dont lighten up a little ARADIA: some of us might suddenly have a lot more of a reason to join the others ARADIA: and find something else to do

Nice way of putting it Aradia. Vriska really needs to Clam down and Krill out, because she’s gonna lose the few she has with her still.

OH SHIT THAT’S THE END OF THE UPDATE. Well then, that’d be my cue to sleep. it’s 2:15 AM an I have summerschool in 5 hours. gnight folks.

#Homestuck #homestuck liveblog #Act Omega #hs act omega #act omega liveblog #hs act omega liveblog

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tuthillscopes-blog · 7 years

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Life On Earth Is Used To Gravity So What Happens To Our Cells And Tissues In Space?

check it out @ https://tuthillscopes.com/life-on-earth-is-used-to-gravity-so-what-happens-to-our-cells-and-tissues-in-space/

Life On Earth Is Used To Gravity So What Happens To Our Cells And Tissues In Space?

Theres one pressure whose effects are extremely deeply entrenched within our everyday lives that people most likely dont think much about this whatsoever: gravity. Gravity may be the pressure that triggers attraction between masses. Its why whenever you drop a pen, it falls down. Speculate gravitational pressure is proportional towards the mass from the object, only large objects like planets create tangible attractions. For this reason study regarding gravity typically centered on massive objects like planets.

Our first manned space missions, however, completely altered the way we considered gravitys effects on biological systems. The pressure of gravity doesnt keep us moored down it influences how our physiques focus on the tiniest of scales. With the possibilities of longer space missions, researchers will work to determine what too little gravity method for our physiology and the way to compensate for it.

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On several weeks-lengthy expeditions wide, astronauts physiques suffer from a gravity-free atmosphere completely different as to the theyre accustomed to on the planet. NASA, CC BY

Free of gravitys grip

It was not until explorers traveled to space that any earthly creature had stayed inside a microgravity atmosphere.

Scientists observed that coming back astronauts had grown taller and had substantially reduced bone and muscle mass. Intrigued, researchers began evaluating bloodstream and tissue samples from creatures and astronauts before and after space travel to evaluate the outcome of gravity on physiology. Astronaut-scientists within the largely gravity-free atmosphere from the Worldwide Space Station started to research how cells grow while in space.

Most experiments in this subject are really conducted on the planet, though, using simulated microgravity. By spinning objects for example cells inside a centrifuge at fast speeds, you may create these reduced gravity conditions.

Our cells have evolved to cope with forces inside a world characterised by gravity if theyre all of a sudden liberated from gravitys effects, things get strange.

Discovering forces in a cellular level

Combined with the pressure of gravity, our cells will also be exposed to additional forces, including tension and shear stresses, as conditions change inside our physiques.

Our cells need methods to sense these forces. Among the broadly recognized mechanisms is thru what exactly are known as mechano-sensitive ion channels. These channels are pores around the cell membrane that let particular charged molecules pass in or out from the cell with respect to the forces they identify.

IMG 3 TT Channels inside a cells membrane behave as gatekeepers, opening or closing to allow molecules in or out as a result of a specific stimulus. Efazzari, CC BY-SA

A good example of this sort of mechano-receptor may be the PIEZO ion channel, present in just about all cells. They coordinate touch and discomfort sensation, based on their locations in your body. For example, a pinch around the arm would activate a PIEZO ion funnel inside a physical neuron, telling it to spread out the gates. In microseconds, ions for example calcium would go into the cell, creating the data the arm got pinched. The number of occasions culminates in withdrawal from the arm. This sort of pressure-sensing could be crucial, so cells can rapidly respond to ecological conditions.

Without gravity, the forces functioning on mechano-sensitive ion channels are imbalanced, causing abnormal movements of ions. Ions regulate many cellular activities if theyre not going where they ought to once they should, the job from the cells goes haywire. Protein synthesis and cellular metabolic process are disrupted.

Physiology without gravity

In the last 30 years, scientific study has carefully teased out how particular types of cells and the body systems are influenced by microgravity.

Brain: Because the 1980s, scientists have seen that the lack of gravity results in enhanced bloodstream retention within the torso, and thus elevated pressure within the brain. Recent studies suggest this heightened pressure reduces the release of neurotransmitters, key molecules that cognitive abilities use to speak. This finding has motivated studies into common cognitive problems, for example learning difficulties, in coming back astronauts.

Bone and muscle: The weightlessness of space may cause greater than a 1 percent bone loss per month, even just in astronauts who undergo stringent exercise regimes. Now scientists are utilizing advances in genomics (study regarding DNA sequences) and proteomics (study regarding proteins) to recognize how bone cells metabolism is regulated by gravity. Even without the gravity, scientists have discovered that the kind of cells responsible for bone formation are covered up. Simultaneously the kind of cells accountable for degrading bone are activated. Together it results in faster bone loss. Scientific study has also identified a few of the key molecules that control these processes.

Immunity: Spacecraft are susceptible to rigorous sterilization to avoid change in foreign microorganisms. Nonetheless, throughout the Apollo 13 mission, an opportunistic pathogen infected astronaut Fred Haise. This bacteria, Pseudomonas aeruginosa, usually infects only immune-compromised individuals. This episode triggered more fascination with the way the defense mechanisms adapts to space. By evaluating astronauts bloodstream samples pre and post their space missions, researchers learned that the possible lack of gravity weakens the functions of T-cells. These specialized immune cells have the effect of fighting a variety of illnesses, in the common cold to deadly sepsis.

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To date there is no quick-fix replacement for gravity. Andy Tay, CC BY-ND

Paying for the possible lack of gravity

NASA along with other space agencies are investing to aid strategies which will prepare humans for longer-distance space travel. Working out how you can withstand microgravity is a huge a part of that.

The present most practical way to beat the lack of gravity would be to increase strain on cells differently via exercise. Astronauts typically spend a minimum of two hours each day running and weight-lifting to keep healthy bloodstream volume and lower bone and muscle loss. Regrettably, rigorous exercises are only able to slow lower the degeneration from the astronauts health, not prevent it entirely.

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Space exercise around the Worldwide Space Station. NASA, CC BY

Supplements are another way researchers are investigating. Through large-scale genomics and proteomics studies, scientists have were able to identify specific cell-chemical interactions impacted by gravity. Now that we know that gravity affects key molecules that control cellular processes like growth, division and migration. For example, neurons grown in microgravity around the Worldwide Space Station have fewer of one kind of receptor for the neurotransmitter GABA, which controls motor movements and vision. Adding more Gamma aminobutyric acid restored function, however the exact mechanism continues to be unclear.

NASA can also be evaluating whether adding probiotics to space food to improve this enzymatic and natural defenses of astronauts might help prevent the side effects of microgravity.

At the begining of times of space travel, among the first challenges was working out how to cope with gravity so a rocket could escape Earths pull. The challenge is how you can counterbalance the physiological results of too little gravitational pressure, especially during lengthy space flights.

Andy Tay, Ph.D. Student in Bioengineering, University of California, Los Angeles

This short article was initially printed on The Conversation. Browse the original article.

Find out more: http://www.iflscience.com/space/life-on-earth-is-used-to-gravity-so-what-happens-to-our-cells-and-tissues-in-space/

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