#Thiamine

[er-cryptid]

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#studyblr #notes #medblr #medical notes #med notes #genetics #genetics notes #basics of genetics #genetics basics #adenine #guanine #cytosine #thiamine #double helix structure

[mcatmemoranda]

Wernicke encephalopathy — Wernicke encephalopathy is due to diencephalic and mesencephalic dysfunction of central gray structures surrounding the third and fourth ventricles secondary to thiamine deficiency. Occurring both in alcoholics and nonalcoholic subjects, it probably is an underrecognized cause of encephalopathy in the intensive care unit (ICU). Patients who are fasting, receiving parenteral nutrition, recovering from gastrointestinal surgery, being fed after a period of starvation, undergoing hemodialysis, or suffering from advanced cancer are particularly susceptible to this disorder [39]. (See "Wernicke encephalopathy".)

Wernicke encephalopathy is characterized by a triad of confusion, ataxia, and ophthalmoplegia. The full triad is rarely present, and variations from the classical description occur commonly. Ocular signs are the hallmark of the disease, including horizontal nystagmus, bilateral abducens palsy, complete ophthalmoplegia, and pupillary abnormalities [39]. Apathy, impaired awareness, disorientation, mental sluggishness, and restlessness characterize the encephalopathy. In extreme cases, coma may be the presenting feature [39]. An agitated form that overlaps with alcohol withdrawal syndrome has been described [7]. Ataxia results from vestibular and cerebellar dysfunction, and hypothermia and hypotension may occur due to hypothalamic dysregulation [39].

Prompt treatment with intravenous thiamine can reverse Wernicke encephalopathy. The ocular abnormalities are the first manifestation to respond to therapy. The ataxia and the encephalopathy may take days to weeks to resolve, and there may be permanent memory and cognitive impairment [39]. All debilitated patients at risk for Wernicke encephalopathy should receive adequate thiamine supplementation. (See "Wernicke encephalopathy", section on 'Treatment' and "Wernicke encephalopathy", section on 'Prevention'.)

#thiamine #Wernicke

[coffeenuts]

#IFTTT #Flickr #alanine #glutamine #thiamine

[drjgodo]

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#chicago #Chicago Chiropractor #chiropractor #Chiropractor near me #Dr. Godo #mosquito #mosquitos #thiamine

[r8lr1odincum]

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#rhinencephalons #acetylaniline #thiamine #pogromize #incubi #tetralophodont #oxyacetylene #Prosopium #proenzyme #traceability #analphabet #embranchment #morrowless #Visakhapatnam #omphalus #metapolitics #Perkoff #unticketed #blawort #discredit

[sybilsherbal]

Vitamin B1 (thiamine) needed for growth and maintaining normal appetite

#vitb1 #vitb #b-complex #thiamine #appetite #growth

[isdalinarhot]

Thinking about when Dalinar told Navani he straight up did not remember Evi and Navani’s immediate first assumption was oh he has that one thing that that one guy from The Man Who Mistook His Wife For A Hat had where he drank so damn much that he got both anterograde and retrograde amnesia for the rest of forever. Which is such a wild assumption when you live on a planet that has magic

#luke.txt #used to have such bad anxiety about developing that but then I found out there’s tons of thiamine in dairy #and I am milklover100 I drink milk with every meal at home and if milk wasn’t a kids thing at most restaurants I’d drink it there too #hurray for lactose tolerance #update turns out there is not tons of thiamine in dairy but there IS in bread #and I am also breadlover100

[homeofhousechickens]

What makes a chicken more or less difficult to raise?

The same reason a golden retriever is less difficult to raise then a husky. Some animal breeds just have different care requirements.

For example Leghorns are a VERY easy chicken breed to raise.

Leghorns are a fast feathering breed, that means chicks are able to thermoregulate and get off heat faster then other breeds.

They do not really need any special chick starter or supplements to raise them. Leghorns are not really prone to any health issues when they are young.

When leghorns are adults they are nonbroody and very productive so they lay lots of eggs that are easy to collect and hatch.

Leghorns are a bit skittish by nature which means they tend to be great at avoiding predators and surviving predator attacks.

Leghorns also have some of the best feed conversion, this means they need to eat less to produce more then other chickens, so feeding them isnt to expensive.

All of the above would make a leghorn quite easy to raise and even breed. They do have some health issues that typically happen to them later in life but they are one of the most popular egg laying chickens for a reason.

Silkies are more so an intermediate breed. I dislike that they are considered beginner friendly for many reasons.

Silkies need to be on a good diet with good thiamine levels as they are prone to deficiency which can lead to a host of problems but most commonly wry neck that ends up very hard to reverse and treat.

Since silkies are fibromelanistic that means their immune system sucks for the first few months. In terms of building their immune system they will always be behind nonfibro birds of the same age due to the mechanics of fibromelanism. This makes them very vurnerable to cocciodosis outbreaks that wluld even bother your other birds when they are young.

Silkies have the hookless/silked gene this means they cannot thermoregulate as well as a normal feathered birds. That means they are more sensitive to hot and cold temperatures. The chicks will sometimes need heat longer due to that as well.

Due to their crest and sometimes beard some silkies become essentially blinded by their feathers making them vurnerable to flock bullying, predation, and starvation. Yep starvation and malnutrition is a COMMON problem with silkies because they cannot see. This means adults can still be prone to wry neck and other issues caused by nutritional deficiencies.

Their fluffy appearance can hide issues very well. If their owner is not picking them up often its very easy to miss things like malnutrition and mites.

Due to all of the above Silkies would be a harder breed to raise then leghorns in my example.

#leghorns actually need more thiamine then other breeds #they do share that trait with silkies but its rarely a problem because leghorns dont suck as much genetically lol #you will not see the same rates of wry neck in leghorns like you will in silkies

[kylejsugarman]

those whump blogs that just sort of post pictures or gifs of characters in pain or hurting from various pieces of media without context should not be allowed to post “el camino” without any context because like. u don’t understand. u don’t understand. u don’t understand. U DONT UNDERSTAND U DONT UNDERSTAND U DONT UNDERSTAND

#syd squeaks #U DONT UNDERSTAND WHAT HES BEEN THRU. MY BABY BOY #nurse ready the niacin and thiamine injections #el camino

[merlions]

Every time I start self invalidating and being like psh I don't REALLY have even minor synesthesia, everyone thinks letters and words and numbers are colors, I offhandedly say some shit to someone like "urgh don't you think it's so god damn hard to remember info about vitamins? Like they have letters AND numbers AND names, it's just way too many colors to be able to connect meaning to them, you know, the normal way one usually memorizes info." and they treat me like an insane person. Like oh I guess that's Not Very Relatable lol

It's just nice to have a change from people treating me like an insane person and a hypochondriac for saying I have mild synesthesia. A nice little variety to add enrichment to the being treated like a silly child. Caught between the rock hard devil and the deep sea place or whatever

#ns tag #fuck b1 thiamin b2 riboflavin b3 niacin b5 pantothenic acid b6 pyridoxine b7 biotin b9 folate and b12 cobalamin or cyanocobalamin #as well as vitamin a beta carotene vitamin c citric acid vitamin e alpha tocepherol vitamin k phylloquinone and menaquinone #and fuck the enriched grains and green leafy vegetables they rode in on #synesthesia

[mcatmemoranda]

Stuff discussed on rounds today:

Hyperglycemic Hyperosmolar Non-Ketotic Coma can cause dehydration and hypernatremia-> AMS.

When blood cultures are drawn, 2 are done to account for the fact that you may get a contaminant in the sample. For example, one of my pt's blood cultures grew coagulase negative staph, which is likely a contaminant.

In hypernatremia, correct Na+ by 0.5 mEq/hour.

Thiamine can be given IV at 500 mg for Wernicke's encephalopathy. Fromt UTD:

Patients with suspected WE require immediate parenteral administration of thiamine. A recommended regimen is 500 mg of thiamine IV infused over 30 minutes three times daily for two consecutive days and 250 mg IV or IM once daily for an additional five days, in combination with other B vitamins

Stress dose of steroids should be given for a pt on chronic prednisone going for surgery. The attending today said to give hydrocortisone 50 mg q8 for a pt we have who is on prednisone 5 mg qd.

Steroids, EtOH, and HIV are the most common causes of avascular necrosis.

One of our pts has a prostate abscess. The prostate is hard to access and it has poor vascularity. It has fat, so a fat-soluble antibiotic is necessary for prostate abscess. The pt we have is on Zosyn.

Lithium toxicity can cause irreversible kidney damage. Can cause nephrogenic diabetes insipidus. You can dialyze it off acutely to prevent this.

Avoid morphine in pts with renal disease. Dilaudid and fentanyl are good for pain control in pts with renal disease.

Albumin less than 1.5, GI bleed, 2nd episode of SBP are indications for prophylactic antibiotics. Enterobacter has inducible resistance to ceftriaxone, so you don't give ceftriaxone to treat enterobacter. Use cefepime or higher.

Biliary obstruction first presents with elevated alk phos. Alk phos is in the cells of the biliary tree

#HONK #hypernatremia #AMS #blood culture #thiamine #Wernickes #blood cultures #BCx #stress dose steroids #stress steroids #avascular necrosis #lithium #alk phos

[werewolf-femboy-maid]

*13 meltdowns later*

hello guys im back

the picture below is from this blog

I would eat these so fast

I would run like ive never run in my life

I would marry both of these if they were people

I want 2,000 of each of these I want to savor them I want to devour them

everything in my soul is begging for the smell of these... oh my god and everything else in the blog looks like it smells really fucjgin goodddddd

there are very specific old smells I cant remember what exactly what some of the smells but my favorites are the smell of that kiddie pool rubber, my Korean grandma's detergent, and cigarets at the beach and the airport and the cities

I guess im a very smell person with my biggish nose

Sad creature hours

ok guys I gotta find a remote job stay safe I love yall

#been a long day #been a long period of itme #I hurtin #bpd awareness month #just got out of a bad episode I was being abusive again im a mess #but were both recovering and talking it out I just have to actually breathe when I get mad #its so hard tho idk why but I have to keep trying #I get overstimulated and forget to ask for something or avoid asking because I think someone will get mae #im so sad about it im just thiamin it out rn #you know what I mean fucik. autocorroec #eh #fyp

[brunchbitch]

learning about different types of dementia/cognitive impairment in my serious illness, death, and dying class and one of them is wernicke-korsakoff syndrome lmao. it is still WILD to me that i could have caused permanent brain damage from my ed. thank fucking god they caught it when it was still wernicke's encephalopathy.

#thiamine deficiency #wernicke's encephalopathy #personal

[suavemuthafcca]

To all of my sexy introverted empaths.... I nonchalantly see you...😉

#empaths #intuitive #mature nympho #nerd stuff #books and reading #no friends #nostradamic #sexy tease #hungry #sacral #frequency #white magic #energy #nature #sunrise #meditation #minfulness #ramenshop #thiamines

[scolek]

someone: "you shouldnt be putting chemicals you cant even pronounce into your body!!"

the one guy whos really good at pronouncing things:

#like its a stupid argument either way but what if my special skill is pronouncing words good. #what if i can read the back of a shampoo bottle unfettered #do you know what thiamine mononitrate is? i do.

[mejomonster]

Happy health news. Mostly rambling tho

AWWW YEAH. So the thiamine (100 mg TTFD), my herbal meds from acupuncturist, physical therapy stretches at home, and just general accupuncture and physical therapy, are working!

Knocking on wood but you know***

I havent needed miralax in a week, I'm experimenting with now lowering amitiza dose since I've been going 4 times a day it seems like I can risk lowering it now without super-risking not going for a week (and the vomiting that comes with it).

Notes for myself:

physical therapy stretches specifically help gi tract rumble and feel hunger, so I should try those when I get nausea or no appetite as they're a quick way to help those symptoms. I should also try to do them daily as they may be helping gi tract function better again. DO THIS when nausea or no hunger!!!

Herbal meds seem to be doing something. Just in that since I've started them I haven't needed miralax thank fuck. They're not hurting anything at least so I'll finish the bottles.

I'm currently doing 1 B complex vitamin (so it's got 200 mg B5 since that helps gi function too), and 1 100 mg B1 thiamine TTFD form capsule. I could significantly push up this dose, either up to 3 a day (which seemed to help some others with gi issues), 5 a day (again helped some with gi issues) or all the way up to 1600 mg (the high dose thiamine recommendation). I think I'll keep it where it is for now since that'll make the bottle last longer. But if I can't use bathroom, I could consider upping this dose as an initial attempt to feel better. Then amitiza, then miralax. That would probably be the gentlest order of trying to fix it. I am still going to take motegrity nonstop as I think the primary issue IS motility so I don't want to slow down motility and make things worse.

The nutritionist gave me a supplement with butryate and glutamine. If I add anything I may add that next, a gi protocol with thiamine mentioned those help gi tract heal. I know in the fall/winter I was given those and they did help significantly with lowering pain, increasing my food tolerance of solids. I figure I either got benefit then and I'm good now, or maybe I could use some more. But since I've already got a new supplement with them I may add them back in.

Nutritionist also gave me 2 digestive enzyme supplements she think will help my tolerance with foods causing intense bloating pain constipation that I'm not actually allergic to, like cabbage broccoli beans kimchi etc. But I can do that later and see if it helps later on.

Right now the first variable I want to keep messing with is thiamine, because it's so far only had small good effect or larger positive effect. It's water soluable, it's easy to take.

I'm low key hoping maybe my recovery will be less than 6-8 months (which is the estimate my acupuncturist gave and the similar case to mine seemed to need 5-8 months based on their timeline) just because I can do a few more things and have done more prior work in recovery besides just taking my gi meds to keep me able to eat. Also for me physical therapy seems to be somewhat helpful, which is something the case study like me did not do.

#rant #my health issues #im really hype about the thiamine tbh #it really has qn immediate effect and i canr believe i didnt know sooner #also hype about physical therapy (helping pain a LOT and digestion somewhat) and accupuncture