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#a preemptive hair loss treatment.....
ganondorf · 6 months
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posts that are like We need to support detrans people too!! like ok but just about every person i've met or seen who actually calls themselves detrans has been super transphobic so 🤷‍♂️
and like the concept of detransitioning inherently like. there's nothing wrong with that and IS something that needs support and like i could not care less if you once identified as trans and then later realized you weren't and idec if you actively Regret transitioning like. what that means to you is your business. but everyone i see who actually calls themselves detrans are always advocating for taking away the rights and happiness of Other ppl because being trans didn't work for them Personally
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elvenferretots · 4 years
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Your (hopefully) friendly neighborhood ferret guy of 15+ years here to break down the practical side of Marshall ferret health: 
  Ferrets should live at least 8-10 years when properly cared for. Responsible breeders I follow on Facebook are having ferrets live at least to that, if not up to 13. Marshall Ferrets gives us a lifespan estimate of 5-8, and that is pretty darn accurate for them. Why?
Three main reasons that I am aware of: poor breeding, diet, and early neuter.
Breeding - These ferrets are bred exclusively for sales factors, namely a sanguine temperament and pretty colors. This means that health is not a longterm consideration, and even the ferrets they produce that come with a “health guarantee” were traditionally only refunded if the ferret was kept on Marshall’s diet and returned to the company to euthanize and autopsy (I have not bought a ferret from them in 16 years, though, so I am unsure if this is still policy. It was for several decades at least). This is not an effective model. By the time an owner knows there is a problem with their ferret, they’ve switched to a healthier food. They are attached and don’t want it killed. They want to give it vet care and a high quality of life. It was common in the 90′s and 00′s for ferret people to pick up the deaf or sick kits and ones with bad temperaments from the pet store to save them from getting sent back and euthanized. This also meant that Marshall kept carelessly producing very pretty, very deaf blaze-pattered ferrets (similar to the merle gene in dogs). They sold like hot cakes! As they get older, it seems like Marshall ferrets are also prone to an extraordinary amount of arthritis as well as lumps and bumps and particularly lymphoma, even compared to regular old cancer-prone ferrets. Juvenile cancer, tumors, and growths are explicitly not included in their guarantee.
Diet - Marshall’s ferret diet and treats are notoriously high in carbs and sugars (although this has also gotten better in recent years; molasses used to be reasonably high on the ingredient list). Because their ferrets are weaned way too young, they are on this diet from the time they should be just on milk to when they should be starting meat or high protein kibble to when they come home with you. Basically, even if you switch them over to something healthy immediately, your ferret has likely started off their life on very much the wrong nutritional foot from 3-4 weeks old, a key time in development. This ferrets should be weaned at 8 weeks, and with their mom until then or 10-12 weeks. I’ve seen babies that could not have been older than 5 weeks old at Petco eating watered down Marshall’s kibble. Ferrets are prone to insulinoma if they consume too much sugar, so most Marshall ferrets will get it sooner or later. There is no known cure, only treatment and then palliative care.
Early Neuter - We have lots and lots of studies on the detrimental effects of early neuter on animals, especially dogs. These ferrets are no exception, and they are neutered far younger than puppies ever are (I cannot find my source that said 4 weeks, but we know at least under 6-7 weeks, since they are fully healed when they ship). Early neutering severely stunts their growth, can cause incontinence if there was a mistake in the procedure due to the animal being so very small (especially common in females when the tiny muscles that control urinary control accidentally get nicked), and is directly related to Adrenal Disease, cancer of one or both adrenal glands. This is another one that nearly every Marshall ferret seems to get eventually if the insulinoma or lymphoma don’t strike first. The most effective treatment we currently know is deslorin implants which will stop the symptoms (heat/rut symptoms, enlarged prostate, incontinence, hair loss, weight loss, etc.) and slow the growth, but there is no known cure, only slowing the disease.
My first ferret was a Marshall from a little local exotic pet shop. He was my best friend. He got juvenile adrenal cancer at barely three years old, and passed on just short of his sixth birthday after extensive vet care including surgery and implants to extend and increase his quality of life.
Nearly everyone in North America gets a Marshall ferret from a pet store as their first. Nearly everyone else here gets Marshall ferrets as rescues. It’s not commonly known that good breeders are an option, and there are so many ferrets sold as the small-cute-new-best-friend at the pet store rather than puppies that they land on Craigslist and in rescue at a tremendous rate. If you know the risks when you get a ferret with the two little blue ear tattoos, you’ll be better able to be preemptive in watching for health issues and having a vet fund squirreled away. You’ll need it.
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buffythecomicslayer · 5 years
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Excerpt from Slayer, book 2: Chosen, by Kiersten White
The world is quiet now.
It used to be so loud. So much chatter, beating, drumming, buzzing buzzing buzzing. The buzzing of it all. It used to keep him awake at night, inescapable, like mites crawling through his veins. Sometimes he would scratch at his arms until they bled, but even the bleeding never dampened the buzzing.
Until it stopped. All the lines to and from the world, all the hungry beings clawing and sucking and pawing at it, everything cut off.
But not him. He is still here. And with everything quiet, he can finally focus. He’s powerless, which is unfortunate but temporary. Everything here is temporary. He will not be.
He strokes his arms, smooth and unscarred, so deceptively human-looking. But he is no human. And this world, this quiet world, this cut-off and free-floating world, this magic-less and empty world, this unprotected and uncontested world, this waiting world—
He will be its god, and everyone will buzz with him beneath their veins, they will breathe and bleed and live and die for him, and it will be good.
Amen.
1
The demon appears out of nowhere. Claws and fangs fill my sight, and every instinct screams kill. My blood sings with it, my fists clench, my vision narrows. The vulnerable points on the demon’s body practically flash like neon signs.
“Foul!” Rhys shouts. “No teleportation, Tsip! You know that.” Even while playing, Rhys can’t help but be a Watcher, shouting out both advice and corrections. He’s not wearing his glasses, which makes his face look vague and undefined. Cillian passes him, mussing Rhys’s carefully parted hair into wild curls and laughing at Rhys’s frustration.
I take a deep breath, trying to clear my head of the impulse to kill this demon I invited into our home and swore to protect. “It’s just soccer,” I whisper. “It doesn’t matter. I don’t even like soccer.”
“Football, bloody American,” Cillian sings, neatly stealing the ball from me. His shorts are far shorter than the January afternoon should permit, but he seems impervious to cold. Unlike those of us who are translucently pale at this point in winter, his skin is rich and lovely. He passes to Tsip. Tsip is a vaguely opalescent pink, shimmering in the sunlight. She paints her claws fun colors when we do manicure nights and I try desperately not to miss Artemis.
I stay rooted to the ground where I’m standing. Tsip caught me off guard, but that shouldn’t matter. I like her. And the fact that I went from trying to score a goal to plotting a dozen ways to kill my opponent in a single heartbeat is frankly terrifying. I can’t get my heart under control, can’t shake the adrenaline screaming through my veins.
“Gotta take over for the Littles. I’m out.” I wave and jog from the field. No one pays me much attention. Jade is lying on the ground in front of the goal, the worst goalkeeper ever. Rhys and Cillian are body-checking each other in increasingly flirty ways. Tsip keeps shimmering and then resolidifying as she remembers the no-teleportation rule. They’re all happy to keep going without me, unaware of my internal freak-out.
I’ve deliberately kept them unaware. Things here are going so well. I’m in charge. I can’t be the problem. So none of them know how I can’t sleep at night, how my anger is hair-trigger fast, how when I do manage to sleep, my dreams are...
Well. Bad.
They don’t need to know and I don’t let them. Except for Doug, his bright yellow skin almost nineties Day-Glo levels in the thin winter sun. Annoying emotion-sniffing demon. He watches me from our goal, his nostrils flared. I can’t lie to him the way I can to everyone else. I shake my head preemptively. I don’t want to talk about it. Not with him. Not with anyone. There’s only one person I want to talk to about it, but Leo Silvera’s not exactly available.
I do a quick sweep of the perimeter of the castle. Leo loved me. Check the woods. Leo betrayed me. Check the locks on the outbuildings. Leo saved me. Pause and just listen and look, feeling for anything pushing against my instincts. I let Leo die.
I keep walking. Leo loved me, betrayed us, saved us, and then died, and I can’t be sad without being mad or mad without feeling guilty or guilty without feeling exhausted.
Past the meadow, the tiny purple demons are taking turns pushing each other on the tree swing. That, or they’re trying to push each other off. It’s hard to tell with them. With nothing else needing my attention outside, I end up at the front stairs to the castle.
“Hey, Jessi.” I wave halfheartedly to our resident vengeance demon. She’s leading the Littles through an elaborate game of hopscotch. George Smythe, bundled up and barely able to see under a floppy knit hat, is shouting each letter as he lands on it. “G!”
“What?” Jessi snaps at me.
“E!”
“I can take over for you.” I find the Littles soothing. They might be three incredibly hyper children constantly needing snacks, entertainment, and education, but at least none of them ever randomly triggers a kill reflex in me.
“A!”
“No,” Jessi says, her voice as sweet as summer fruit. “G-E-what-comes-next...”
“O!” George course corrects, wobbling on one short leg before jumping to the required O.
“Good! Oh, you’re so clever. Priya, how are your letters coming?” Priya, a tiny moppet with shiny black hair, is crouched over her own chalk work, which looks more like Klingon than any alphabet I’m familiar with. “Very good, darling! You’re really working hard. Hold the chalk with one hand, like we talked about. Thea, love, fingers out of noses, please — that’s a dear.”
And to think, we once considered these children the entire future of the Watchers. I watch as Thea spins until she falls flat on her bottom. Actually, the future of the Watchers is pretty accurately captured here. I pat Jessi on the arm. “So, you can take the afternoon off.”
Everything sweet in Jessi’s voice turns to ice. “I said no. I don’t trust you with these three precious wonders. We have an entire day’s curriculum to get through, and we haven’t even done story time yet or finished our art projects. Are you going to do any of that with them?”
“I— I could?”
“You were going to turn on a cartoon and read while their fertile minds were filled with weeds.”
Jessi doesn’t have her powers anymore, but I’m pretty certain if she did, I would have been vengeance-demoned right into something oozing and seeping. She’s already turned away from me and back to her three charges. Her whole face is full of gentle warmth and absolute love.
“R!” George declares, hopping emphatically down on it. Jessi claps like he’s cured the common cold.
Thoroughly dismissed, I skulk up the stairs and into the castle. Jessi could at least pretend to be nice. She’s got a lot of enemies out there — vengeance is a nasty cycle — and without her powers she’s vulnerable. We took her in despite her obvious hatred for everyone over the age of ten. There was some debate, given her history, but my mom argued in her favor. It’s a little easier to forgive a vengeance demon who made it her immortal life’s work to avenge children than a vengeance demon who specialized in, say, fantasy league sports rivalries.
But Jessi’s dismissal leaves me with nothing to do. I used to have my medical center and my studies, all my little Watcher duties. Even with so few of us, the castle ran as near to Watcher traditions as we could manage. Which in retrospect was absurd, since we didn’t have a Slayer and weren’t actually doing anything Watchers should.
But now everything has changed. We lost Watchers — Wanda Wyndam-Pryce, sulking off into the sunset, good riddance. Bradford Smythe, murdered. Eve Silvera, secretly a succubus demon and murderer, smushed thanks to my actions. Artemis, off to find herself with her awful girlfriend, the thought of whom makes my jaw ache as I grind my teeth. And Leo, who didn’t warn us what his mother was (and what he was) but fought her to give us enough time to stop her from opening a new hellmouth.
And now we have a Slayer, again some more, thanks to Leo somehow returning the powers his mother stole from me. I don’t know how he did it, and it hurts too much to think about, like everything else. I spend so much of my days trying not to think, and it’s harder than it should be. I used to believe that all Slayers did was act without thinking. I was wrong, but I wish it were true. There’s so little acting and so much thinking these days.
It’s good. It’s all good. It’s good, I remind myself, over and over like a chant. Sanctuary, what we decided to turn our castle into, is just starting out, but it’s exactly what we dreamed it could be. We’ve taken in demons who had nowhere else to go. We’re keeping them safe, and ourselves safe, and we’ll keep looking for those who could benefit from the generations of knowledge and abilities we have. We’re protecting, not attacking or destroying.
Between our new demonic additions and existing Watchers, everyone has tasks and times to do them. It’s more work than anyone anticipated, keeping everyone taken care of and fed, making sure the castle runs like it should. But so far everyone is happy. Everyone is safe.
I sink down against the wall, feeling the cold of the stone radiating outward. The unpellis demon, all four gentle eyes soft and brown and hopeful, snuggles up to my side like a dog. It’s more animal than human in nature, nonverbal, and still recovering from its frequent de-skinning treatment in Sean’s demon-drug manufacturing scheme. I saved Pelly from that cellar.
I didn’t save everyone, though.
I wrap my arms around Pelly and close my eyes. Everything is exactly what we dreamed it could be. Except I feel Leo’s loss everywhere, and I miss my twin, Artemis, with a constant, physical ache.
And, worst of all, with enough time after Tsip surprised me to calm down and remind my body there’s no danger...
I still feel like killing something.
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goodreadsblog · 3 years
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Just How To Pick Best Hair Restoration Strategy For You
Hair loss is actually a very common factor. Many men will start experiencing detectable hair loss at around the age of 35. Later, due to the age of 50, it is actually around 85%. This problem isn’t special to males either, as girls go through hair loss very typically. With this being actually such a popular issue formany people, there are actually a handful of answers accessible.
A bunch of them are effective, yet regrettably, a lot of them don’t. It can seem to be fairly hard to locate the one that performs, and sadly, picking the inappropriate one just leaves you with much less funds and also a ton of delayed. These handful of ideas ought to assist you out in finding out which strategy you should opt for.
Strategy for New Jersey Hair Restoration
Hair transplantation surgical treatment
Hair transplantation surgical operation is a really trusted selection for hair restoration new jersey. It has actually felt better and much better throughout the years, thus if you might have listened to bad aspects of it, it has likely strengthened significantly ever since. It is actually safe as well as really trustworthy, so there is actually nothing at all to stress over other than cost, which may unquestionably be actually very higher.
The end result is actually very credible as well as most individuals find yourself deciding on the operative route. You are going to get an even more organic look, and all though it could be costly, most individuals who have undergone a hair transplantation surgical treatment have apparently pointed out that they do not lament a factor. In a community where appears appear to matter pretty a whole lot, it’s complicated not to feel those who mentioned that acquiring tenacity and performing this approach is actually certainly worth the amount of time and amount of money.
FUT
The so-called FUT method of hair transplanting is actually a method that is actually a little much more complicated, yet in the past handful of years, it became reputable good enough for folks to utilize it. This sort of New Jersey hair transplant is pretty brand new, a minimum of reviewed to a few other techniques, just being around for 20 years currently.
It was actually a cutting edge creation and it can a transplant thus credible that would certainly not have been possible just before that. Of training course, this method has its downsides. It takes rather long to do, around 2 hrs, as well as it, sadly, leaves rather a significant scar astride your head.
Anyway, this is actually the choice with a much better result, and additionally takes much less attend surgical treatment than FUE, which is why many individuals discover it a lot more desirable. Our checklist definitely would not be comprehensive if we failed to detail the FUE procedure, thus let’s take an appearance at that one.
FUE
The FUE approach was actually particularly built as a method to receive an identical impact as FUT while preventing some of its own biggest problems, the scar on the back of the scalp. It likewise includes taking hair roots coming from the back of the head to produce a better hairline. This procedure takes a lot longer than FUT, though it lowers the pain that you would certainly experience after a FUT surgical procedure. There is actually likewise no demand for any kind of cut treatment and therapy hereafter surgical procedure.
Picking from these pair of has its upsides and also disadvantages, however you must always speak to a physician prior to choosing either to avoid any type of uncertain problems.
Reclaim your hair without surgical procedure
Besides a hair transplantation surgical procedure, there are actually other, more economical, though less trusted procedures to regain your hair. Permit’s take a look at a few of them.
Hair loss medication
There are a great deal of various clinically authorized hair loss products to decide on. They are actually typically arranged into two classifications, Androgen-dependent as well as Androgen-independent. Androgen-dependent products feature medications that stop the conversion of testosterone in to dihydrotestosterone. Dihydrotestosterone is the hormone that is felt to become one of the root causes of hair loss in men. This kind of medicine helps out most during the course of the early stages of balding. It won’t affect until a few months thus, you will definitely need to wait a little bit until you get the outcomes you prefer. Androgen-independent medicines, however, are actually also usable through ladies. This type of item expands small blood vessels in your body. Although it still isn’t recognized why specifically this improves hair growth, it performs. After a handful of months of using these kinds of items, you need to expect a rise of around 40%.
Hairpieces
Hairpieces have actually been a reliable loss of hair solution throughout past. Although there are definitely far better and advanced techniques to resist this problem, a hairpiece is actually easy and also basic to use. There are actually different kinds of hairpieces, and they all have their benefits and drawbacks, yet we won’t be actually boing right into that in this particular write-up. In any case, wigs are actually a great option for anybody who can not afford the amount of time and money for a health care or medical technique.
Ensure to get in touch with a medical professional
The most effective factor you may do when it pertains to hair loss is to explore a physician. Contacting a physician as soon as you start to observe any type of indicators of hair loss are going to allow you to take any preemptive solutions. Just before choosing any kind of loss of hair products, or even particularly prior to completing surgical operation, you ought to get the point of view of a medical professional.
You should likewise find what your doctor thinks about any kind of medicines you are actually thinking of making an effort. Obtaining the viewpoint of a doctor, before you get an item can spare you a bunch of cash, considering that, unfortunately, a lot of these items that claim to become able to recover your hair, are simply a scam.
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tabloidtoc · 4 years
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National Enquirer, June 8
Cover: Chinese COVID-19 Cover-up -- defecting diplomat murdered in Israel 
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Page 2: Former Jenny Craig weight-loss spokesperson Valerie Bertinelli is packing on the pounds again and said she doesn’t care anymore 
Page 3: Disgraced former Today host Matt Lauer has come out guns blazing in his own defense claiming the rape charges against him were not only false but widely embraced by the #MeToo movement without proper verification 
Page 4: Ryan Seacrest shocked audiences with his slurred speech and shriveled eye on the finale of American Idol prompting fears he could go blind, busybody Jennifer Aniston and cagey ex-husband Justin Theroux are playing cat-and-mouse with each other about their love lives -- while Justin’s been living the single life since their 2017 split Jen is doing everything she can to get the details about his dates 
Page 5: Celebrity Cov-Idiot of the Week -- Maurice Fayne has been arrested for taking millions in emergency money from the government and spending it on over-the-top blind like a Rolex watch, a diamond bracelet and a 5.73 carat diamond ring plus leasing a Rolls-Royce Wraith and paying $40,000 in back child support from money loaned his company under the Paycheck Protection Program which is supposed to be used to prop up small companies during the COVID-19 crisis 
Page 6: The tragic overdose death of Melissa Etheridge’s son Beckett Cypher has insiders fearing for the well-being of his sperm-donating dad rock legend David Crosby -- David had an active role in the boy’s life and with his long list of health woes his friends are afraid he won’t be able to stand the strain of a loss like this 
Page 7: Wannabe actor Prince Harry is so desperate to make it big in Tinseltown that he’s subjecting himself to a grueling Hollywood boot camp and has signed up for a string of special classes and training sessions to follow in the footsteps of his actress wife Meghan Markle, Chip Gaines is going to trial in a million-dollar lawsuit against former partners who accused him of swindling them out of a fortune 
Page 8: Last year doctors concluded that Dolly Parton’s face had been partially paralyzed by Bell’s palsy and she may never sing again -- two videos last month showed her barely able to move her lips and struggling to get her words out and medical experts have warned she also may have suffered a ministroke, Brian Austin Green finally admitted his marriage to Megan Fox is finished
Page 9: Phyllis George was hailed as a TV pioneer when she broke up the boys’ club as the first female anchor of The NFL Today but faced humiliation after being shredded by horrific reviews as an anchor on CBS Morning News -- Phyllis died brokenhearted at 70 following a long illness 30 years after being run out of network television 
Page 10: Hot Shots -- Kristin Chenoweth and her dog Thunder, Chris Sullivan on a bike ride in Brentwood, Pierce Brosnan goes snorkeling in Hawaii, Dean McDermott and son Beau 
Page 11: Tom Cruise is keeping his romance with Sofia Boutella secret and is even donning disguises to avoid detection when he sneaks out to see his co-star from The Mummy, Zooey Deschanel’s pals think her hot romance with Property Brothers star Jonathan Scott will be a flash in the pan because she’s only interested in him for booty calls and raising her profile 
Page 12: Straight Shuter -- comedian Michael Showalter with shopping bags and coffee (picture), in a 2008 interview with Beyonce on the Tyra Banks Show all the questions were cleared in advance with Beyonce, friends and fans are worried about Adele’s recently unveiled massive weight loss because this is a cry for help from someone who’s always claimed she was very comfortable being her size and would never go all Hollywood skinny, now that Bruce Willis and Demi Moore have spent time together in lockdown the former couple are looking to make it permanent with Demi moving in with Bruce and his wife Emma and Emma is the driving force behind the idea -- she loves Demi and wants to get a place where they can all live together, super-healthy Gwyneth Paltrow didn’t always live on a strict diet but as a struggling actress she seemed to survive on cigarettes alone
Page 13: Kristin Cavallari’s diva behavior was behind the demise of her reality show as ratings for E!’s Very Cavallari plummeted in the third season and many of the crew say it was because she’s a royal pain, blowhard Alec Baldwin has been browbeating his pregnant wife in lockdown after Hilaria offered to cut his hair and he replied I don’t think she knows what she’s doing -- Hilaria and Alec hoped her latest pregnancy would boost their sagging union but his behavior may be a sign that the glow of the pregnancy has worn off, Jonah Hill doesn’t go anywhere without his dog Carmela but his pals said the dog stinks
Page 14: True Crime 
Page 15: Internet hackers who stole a trove of celebrities’ information from law firm Grubman Shire Meiselas & Sacks are getting desperate as the FBI closes in on their $42 million extortion scheme, devastated Mary-Kate Olsen is begging sister Ashley Olsen for help navigating her ugly divorce from Olivier Sarkozy and the twins are working up a game plan to protect the $500 million fortune they built together from the French banker 
Page 18: Real Life 
Page 19: George Clooney has resurrected his decades-long feud with romance-novel cover icon Fabio Lanzoni which was so bad the two had to be separated during a vicious confrontation in a Beverly Hill restaurant -- now that George moved back to L.A. after spending years at his homes in England and Italy their rivalry has reared its ugly head again because they run in a few of the same circles and word has gotten back to Fabio that George thinks he’s some type of big shot who deserves special treatment, Ruby Rose landed the role of a lifetime as the title superheroine in Batwoman but after the dark drama turned into a disaster she flew the coop -- Ruby was the face of the show and she got the blame when the writers didn’t do as good as job as they could have plus there was also a lot of fighting behind the scenes among writers and producers
Page 21: How to teach your kids 
Page 22: Health Watch, Ask the Vet 
Page 24: Sarah Palin and her husband Todd are no officially divorced 
Page 26: Cover Story -- Doomed Du Wei was China’s ambassador to Israel and he knew too much about his country’s involvement in the COVID-19 pandemic and its evil expansion plans and he paid with his life 
Page 30: Scott Disick has been hit with a second wave of heartbreak after girlfriend Sofia Richie ditched him after he checked into rehab to treat past traumas caused by the death of his parents and Sofia has already been hanging out with a new mystery man, Hollywood Hookups -- Rooney Mara and Joaquin Phoenix are expecting, Dan Soder and Katie Nolan dating, Katie Maloney-Schwartz and Tom Schwartz are ready to start a family 
Page 32: Kanye West’s ridiculous rules and drastic demands have earned him the title of the worst boss in Hollywood and the bad rap has wife Kim Kardashian at her wit’s end, they’re liberal laugh legends but Bill Maher and Stephen Colbert can’t stand each other and they don’t need a camera running to batter each other with punch lines -- Stephen thinks Bill is pompous and Bill thinks Stephen is a smart-ass 
Page 34: Jennifer Lawrence admitted on Amy Schumer’s new cooking show that she can’t even wait for darkness to fall before drinking alcohol and getting her private house party going -- she said she tries to wait until 6 so she has a preemptive beer at 5, Charlize Theron hates ex Sean Penn so much she pretends he doesn’t even exist -- she dated Sean for a year and a half before calling it quits in 2015 but in 2019 she insisted she’d been single for a decade 
Page 36: Nicole Kidman shattered her ankle in a freak accident while running through their Nashville neighborhood and now her husband Keith Urban and concerned pals fear the effects may cripple her career 
Page 42: Red Carpet Stars & Stumbles -- designer Atelier Versace -- Lupita Nyong’o, Anne Hathaway, Jessica Alba 
Page 45: Spot the Differences -- Nancy Lenehan and Liza Snyder in Man with a Plan 
Page 47: Odd List 
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kathleenseiber · 5 years
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Method may predict if radiation will work on tumors
Doctors may someday be able to advise cancer patients to skip potentially grueling radiation therapy that won’t work on their specific tumors, a new study suggests.
The findings, which appear in Cancer Research, could potentially lead to a non-invasive method for identifying patients are who ill-suited for radiation treatment, which would reduce medical overtreatment and help patients avoid adverse effects of radiation.
“Our eventual hope is to be able to predict a patient’s response before radiation therapy even begins, thus sparing patients whose tumors can’t be treated with radiation from going through the arduous multi-week process, saving them both time and money,” says Ishan Barman, assistant professor of mechanical engineering at Johns Hopkins University and one of the study’s corresponding authors.
Typical radiation therapy delivers small doses of radiation over a period of five to seven weeks. There is currently no definitive way to predict treatment response before or even in the early weeks of therapy. The earliest clinicians can examine tumor shrinkage is two to three weeks after therapy, using CT and MRI scans.
Side effects of radiation treatment differ depending on the cancer involved, but can include fatigue, hair loss, nausea, diarrhea, swallowing issues, shortness of breath, and fertility problems, among others, the National Cancer Institute says.
Radiation in small doses
While other studies have investigated molecular changes in tumors as a way to preemptively identify tumors that will not respond to radiation treatment, Barman’s team says its study is unique.
Team members studied multiple types of cancers and used smaller doses of radiation, which more accurately reflects current radiation therapy practices.
“Previous researchers used a single large dose of radiation, resulting in biomolecular changes that don’t accurately mimic the subtle changes caused by smaller doses delivered over longer periods of time,” says first author Santosh Paidi, a mechanical engineering graduate research assistant.
Researchers used Raman spectroscopy, employing laser light to examine how molecules vibrate. Using that method, they were able to characterize changes in the biochemical composition of a tumor and its environment. This method, the researchers say, requires only a low-power laser and doesn’t need any additional sample preparation; such technologies enable holistic examination of the complex biological process of radiation treatment.
“This is only the first step of a larger research endeavor to determine how head and neck cancer tumors respond to radiation.”
To test the difference in response from tumors that are sensitive to radiation and those that are resistant, the researchers used cell lines of both resistant and sensitive tumors from human lung cancers as well as head and neck cancers to grow tumors in mice.
After the tumors grew to a certain size, the research team removed them and scanned them with a Raman spectroscopy system. All four tumor types showed changes in response to small doses, meant to replicate clinical radiation therapy practice in humans, given over the course of two weeks.
The researchers also found consistent changes in lipid and collagen content in both lung, and head and neck tumors.
Ultimate goal
For the second part of the experiment, the research team examined untreated lung tumors. Raman spectroscopy provided data that allowed the research team to distinguish between radiation-resistant and radiation-sensitive tumors, thus providing key insight into the roles different molecules may play in making tumors resistant to radiation.
The research team found subtle differences in each tumor type’s spectrographic signature. After analyzing these patterns, the researchers created an algorithm that identified radiation resistance and sensitivity with a 97 percent success rate.
“This is only the first step of a larger research endeavor to determine how head and neck cancer tumors respond to radiation,” Barman says.
“The ultimate goal is to build a miniature probe that can fit into a laryngoscope. Hopefully in the future, then, when a clinician performs an endoscopy and looks at a patient’s cancerous tumor, they’ll be able to determine whether that tumor will even respond to radiation therapy, and that can improve treatment plans.”
Additional researchers are from Johns Hopkins, the University of Arkansas, and the University of Arkansas for Medical Sciences. The National Institutes of Health, Johns Hopkins, the Arkansas Biosciences Institute, the Medical Research Endowment Fund, the Winthrop P. Rockefeller Cancer Institute, and the Center for Microbial Pathogenesis and Host Inflammatory Responses funded the work.
Source: Johns Hopkins University
The post Method may predict if radiation will work on tumors appeared first on Futurity.
Method may predict if radiation will work on tumors published first on https://triviaqaweb.weebly.com/
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cyclicallife · 7 years
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i have witnessed my hair fall out three different times due to chemotherapy treatment. the first time was quite a shock. i looked down one morning to see hair covering my pillowcase. but the real shock came when realizing how quickly it happened, how quickly the chemicals flooded my system and started killing off cells. my very first, “conventional” round of chemo was administered on a bi weekly basis, if i remember correctly. this gave me a week in between to rest and recover before the next round. because the timing of everything was so fast, i started the first round of treatment almost immediately after returning home, to new england, and, as such, had a full head of hair and a beard. i know some people cut their hair close and shave preemptively prior to treatment, i didn’t have time. anyways, on the first off-week, the first week in between cycles, i awoke one morning and discovered my pillowcase covered in my hair. that same morning i stood in the shower and watched as the water deepened due to the clumps of hair forming in and around the drain. i didn’t know then that i would witness this shedding (a term i’ve come to enjoy & one i find apt) another two times in the very near future.
the sensation of losing one’s hair, especially at the rate in which it falls out due to chemo, is unnerving, to say the least. hair, to me, has always held this sort of sacred energy; it is a connection to the past and holds information about various aspects of our life. during treatment, when it begins to fall out in fistfuls, it’s hard to rationalize this loss by saying “it’s the chemo doing its job” when one understands it to be the result of the indiscriminate killing off of cells. it doesn’t necessarily target rogue cells or cells that have gone haywire and/or rapidly dividing cells, etc… this has always been the thing that has frightened me about chemotherapy treatment — it is simultaneously saving someone and killing them.
for me, a closely cropped head of (already thinning) hair is the norm. however, when the eyelashes fall out and the eyebrows thin to near nonexistence, it is hard to look in the mirror and not feel alien within one’s own body.
just as i’ve witnessed the loss of my hair 3 different times, i’ve also had the pleasure of watching it return. and, in all honesty, it is a pleasurable experience to watch such a seemingly spontaneous rebirth occur. this time around the timing couldn’t be better as the days become shorter and cooler i’m slowly sprouting a new beard & checking daily the fuzzy growth appear & thicken atop my head.
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Candace Cameron Bure Claps Back at Troll After Getting Body Shamed for Her Weight
Candace Cameron Bure Claps Back at Troll After Getting Body Shamed for Her Weight
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Candace Cameron Bure Claps Back at Troll After Getting Body Shamed for Her Weight
Play VideoYOU MIGHT LIKEINSIDE HARRY AND MEGHAN'S PRIVATE RECEPTION SPEECHES: 'THERE IS NO DOUBT HOW IN LOVE THEY ARE'THE BACHELORETTE’S BECCA KUFRIN IS ENGAGED: “IT WAS THE HAPPIEST MOMENT OF MY LIFE!”I'M MORE THAN MY AGE
The actress responded to an Instagram comment on a picture of her and her son Lev.
MARIA PASQUINI
May 02, 2018
Candace Cameron Bure isn’t here for people’s negative comments about her weight.
Responding to a comment left on a sweet picture of the 42-year-old Fuller House star cuddling up with her 18-year-old son Lev, Bure spoke out against an Instagram user who left a body shaming comment about her figure.
“All that excercising [sic] and you still look like you weigh more than your husband, did you change your diet?” the social media user wrote in a comment found by the @commentsbycelebs Instagram account, which seemingly mistook Bure’s 18-year-old son for her husband of over 20 years, Valeri Bure.
Although Bure chose not to correct the social media user on that point, she did speak out against their body-shaming  comment.
“If a 25 inch waist looks big to you … then you’re looking through an altered lens. Be well,” she wrote.
RELATED: Candace Cameron Bure Is in Her Best Shape at 40: ‘I Feel the Most Fit and Strong That I’ve Ever Felt in My Life’
The Fuller House star previously told PEOPLE that she “feels the most fit and strongthat I’ve ever felt in my life.”
In addition to fitting in workouts whenever possible, which can consist of anything from “a 20-minute workout a couple of times a week, or an hour five times a week,” the actress attributes her toned physique to the healthy diet she follows.
“I eat a very plant and grain-based diet,” she said. “I follow a more Mediterranean diet, so I eat lots of fresh vegetables and whole grains and fish. I don’t eat dairy very often, and I’ve cut most of the sugar out of my diet — I see the biggest effect from not eating as much sugar.”
RELATED: Candace Cameron Bure on Her Struggles with Bulimia: ‘It Was Never About the Weight, It Was an Emotional Issue’
While Bure has been open about struggling with bulimia when she was younger, she has recovered from it.
“It’s something that I’m always aware of and that I do think about, but having been healthy for so many years, it’s not something I have to think about on a daily basis,” she remarked. “It’s not something that I struggle with anymore. I really found my joy in fitness, and then as I get older I’ve just been fine-tuning my diet and I enjoy eating what makes my body feel the best.”
“I feel a real sense of accomplishment about what my body can still do, and I want to keep it in shape and keep it strong for so many years that are ahead of me,” she told PEOPLE. “You kind of take your body for granted when you’re younger, so the older I get the prouder I am of the things I’m able to do with it.”
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apextours-blog · 7 years
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Kidney Transplant- donate a life!
That one incident just moved me away. One of my friends’ mother was suffering from kidney failure. Both of the kidneys had stopped functioning. Her mother’s condition was getting worse and the only solution was, kidney transplant​. And her father was the donor himself. The air was suddenly emotional. But, I thought, how many of the patients are really lucky to have a donor or to have a new life? Before getting into the transplant details, it is equally necessary to know about symptoms and causes of kidney failure.
Symptoms and causes:
Kidney’s main functions are keeping the balance of water and minerals in your blood, removing waste from your blood after digestion, and exposure to chemicals or medications. And if your kidney suddenly stops working the results are:-
Not enough blood flow to the kidneys. Problems in cleansing your blood. Waste products and fluid can build up in your body. Enlargement of prostate that blocks your urine flow.
Doctors also refer this condition as acute renal failure. And when your kidneys don’t work well for longer than 3 months, doctors call it chronic kidney disease.
And the most common causes of end- stage renal diseases are:- Diabetes (type 1 and 2) Uncontrolled high blood pressure Polycystic kidney disease
What is the solution?
People having end- stage renal disease or kidney failure have to undergo dialysis or kidney transplant. As we have two doors open here, which one to choose? This question may arise.
As compared to dialysis, kidney transplant has plus points in these matters:
Lower treatment cost Lower risk of death Better quality of life Fewer dietary restrictions
But, for some patients it is advisable to go with dialysis rather than kidney transplant. And some of the factors are:-
Heart diseases Aging factor Who are or were patients of cancer Alcohol or drug abuse Dementia Higher chances of rejection of the organ
The donors and the procedure:-
There are mostly two types of the donors:- Living​ donor Deceased donor
Receiving the benefits of kidney transplant before needing to go on dialysis, this procedure known as preemptive kidney transplant.
How long you have to wait for a deceased donor organ depends on the degree of matching or compatibility between you and the donor. Family members are often the most likely to be compatible living kidney donors. But, also donors may happen to be unrelated people.
The procedure:-
Before proceeding for the kidney transplant, few factors are to be evaluated, for the matter that whether the donor kidney is good match for you. And those factors include:-
Blood type should be compatible. Cross match test involves mixing a small sample of your blood with the donor’s blood in the lab.
The procedure starts with general anesthesia. The doctor makes a slit and places the new kidney in your lower abdomen. The blood vessels of the new kidney are attached to blood vessels in the lower part of your abdomen, just above one of your legs. The new kidney’s ureter is then connected to your bladder.
After that you are supposed to be in hospital under supervision of your transplant team for few days. And after leaving the hospital, you are required to take medicines for rest of your life. That is to prevent rejection of donor’s kidney.
Everything comes with a risk!
Kidney transplant is not a cure at all. It can be counted as an advanced treatment to your kidney diseases. Few of the symptoms may return even after the transplant.
The complications and risks of kidney transplant are because of major two reasons:-
The complications in the surgery itself. Beaches of the after treatment medications.
And these reasons may lead to:-
Acne Diabetes Excessive hair growth or hair loss High blood pressure High cholesterol Increased risk of cancer Infection Weight gain Blood clots Bleeding
Results:-
After a successful kidney transplant, that new kidney will filter your blood. If you were in trauma of dialysis, then it will no longer terrify you.
It may be the case, that your body may reject the donor’s kidney. And for its remedy, you need medications to suppress the immune system​. Your doctor may also prescribe antibacterial, antiviral and anti fungal medications.
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Putting the Human in Human Services
Healing is a journey that may begin with a diagnosis and ideally, end with a positive outcome. The twists and turns that accompany it could be dizzying. In the case of Ondreah Johnson, RN who I have written about in previous articles, the voyage began when she detected a lump in her breast on Christmas night, 2016. She is open to considering it “another gift.”
As a home care nurse, she was accustomed to being the one offering the advice and instruction to her patients for most of her professional career that spans 37 years. Matter of fact medical care blended with compassion, has been her way. She is good at what she does. I would certainly trust her to take care of me and anyone else I know.
Now she is on the other side of the stethoscope and blood pressure cuff. I am writing this as I am sitting in her living room, listening to the gusts of wind woosh through her open living room window on a rare late February, but feels like Spring day. The winds of change are certainly blowing through her life.
We went to the hospital this afternoon for a check-in and a Neulasta injection that helps to boost her white blood cells during chemo; (second round yesterday) one of the first steps as she has boarded what she calls the ‘C-train,’ refraining from using the actual word. She is using modalities both mainstream medical and complimentary including dietary change. supplements, modalities such as Reiki and sound healing. At the moment, she is experiencing a distance healing from friends via a Skype call.  She has asked local friends to stay with her for the day of and few days following her treatments. This is my weekend. Although she is doing well, in the grand scheme of things, side effects have come to call that include GI distress and the beginnings of hair loss. A week or so ago, she preemptively cut her already relatively short hair even closer to her head, to make the transition smoother and less of a shock to the system. Today, a small clump came out in her hand.
As a medical social worker, I too have offered support, comfort and guidance to those facing life changing and challenging conditions. When I am on one side of the treatment team, I have a sense of professional objectivity. On this side of the equation, I am witnessing my friend going through the process and it isn’t always easy to maintain that state. Today, as I sat with her in the sterile looking room at her local hospital, we were chatting with the oncology nurse who was validating the experience that Ondreah and many patients have with the side effects. It occurred to both of us, that as caring as this woman was, she and her patients could have benefitted from some of what we brainstormed about as we sat at her kitchen table sipping home-made chicken soup afterward.  
Many on her treatment team are curious and even fascinated by her requests that they come closer when talking to her, and sit at her level, rather than towering over her. She encourages them to make eye contact and use the verbiage that she is comfortable with. One medication was referred to by the nurse as “the red devil,” while Ondreah called it “the red rooster”. She is an anomaly who brings items that make her comfortable during her treatment process. Crystals, prayer icons, a picture of one of her spiritual teachers, water, snacks (in case she is there longer than expected), two colorful shawls; one for her shoulders and another to wrap around her head, music and angel cards accompany her. Although this might seem like “cosmic foo foo,” a study conducted by the CDC (Center for Disease Control) lead author Heather Jim, PhD. indicates, “In our observational study, we found people who found feelings of transcendence or meaningfulness or peace reported feeling the least physical problems.” Each of these items are part of her everyday life, so they provide comfort amid an otherwise stressful experience.
Medical facilities are offering complimentary therapies that stand side by side with mainstream practices.
We contemplated having her create a program for medical schools and treatment centers by which they would offer much-needed services that (equally as important as what the rest of the oncology team does) meet the patients where they are emotionally, physically, mentally and spiritually. The treatment rooms could have music piped in, or encourage recipients to bring their own to ease the effects of the chemicals flowing through their veins.
Reiki practitioners could offer their services during infusion and/or in surgery, since it has been shown to make a difference in pain and comfort levels. An assessment would include their spiritual practices and what they believe about the dis-ease that is impacting their lives. Do they fear it is a death sentence or a detour along the life path they thought they were traveling? Is it something from which they can learn and grow? Can they use it as a springboard for creating a new life?  Could it offer them freedoms they had not allowed themselves prior? What is their belief system vis- a ‘-vis the God of Their Understanding and the role of faith in healing?
Such an amenity could put the human in human services, knowing that any health care professional is one medical test away from being on the receiving end of treatment.
from World of Psychology https://psychcentral.com/blog/archives/2017/03/12/putting-the-human-in-human-services/
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Putting the Human in Human Services
Healing is a journey that may begin with a diagnosis and ideally, end with a positive outcome. The twists and turns that accompany it could be dizzying. In the case of Ondreah Johnson, RN who I have written about in previous articles, the voyage began when she detected a lump in her breast on Christmas night, 2016. She is open to considering it “another gift.”
As a home care nurse, she was accustomed to being the one offering the advice and instruction to her patients for most of her professional career that spans 37 years. Matter of fact medical care blended with compassion, has been her way. She is good at what she does. I would certainly trust her to take care of me and anyone else I know.
Now she is on the other side of the stethoscope and blood pressure cuff. I am writing this as I am sitting in her living room, listening to the gusts of wind woosh through her open living room window on a rare late February, but feels like Spring day. The winds of change are certainly blowing through her life.
We went to the hospital this afternoon for a check-in and a Neulasta injection that helps to boost her white blood cells during chemo; (second round yesterday) one of the first steps as she has boarded what she calls the ‘C-train,’ refraining from using the actual word. She is using modalities both mainstream medical and complimentary including dietary change. supplements, modalities such as Reiki and sound healing. At the moment, she is experiencing a distance healing from friends via a Skype call.  She has asked local friends to stay with her for the day of and few days following her treatments. This is my weekend. Although she is doing well, in the grand scheme of things, side effects have come to call that include GI distress and the beginnings of hair loss. A week or so ago, she preemptively cut her already relatively short hair even closer to her head, to make the transition smoother and less of a shock to the system. Today, a small clump came out in her hand.
As a medical social worker, I too have offered support, comfort and guidance to those facing life changing and challenging conditions. When I am on one side of the treatment team, I have a sense of professional objectivity. On this side of the equation, I am witnessing my friend going through the process and it isn’t always easy to maintain that state. Today, as I sat with her in the sterile looking room at her local hospital, we were chatting with the oncology nurse who was validating the experience that Ondreah and many patients have with the side effects. It occurred to both of us, that as caring as this woman was, she and her patients could have benefitted from some of what we brainstormed about as we sat at her kitchen table sipping home-made chicken soup afterward.  
Many on her treatment team are curious and even fascinated by her requests that they come closer when talking to her, and sit at her level, rather than towering over her. She encourages them to make eye contact and use the verbiage that she is comfortable with. One medication was referred to by the nurse as “the red devil,” while Ondreah called it “the red rooster”. She is an anomaly who brings items that make her comfortable during her treatment process. Crystals, prayer icons, a picture of one of her spiritual teachers, water, snacks (in case she is there longer than expected), two colorful shawls; one for her shoulders and another to wrap around her head, music and angel cards accompany her. Although this might seem like “cosmic foo foo,” a study conducted by the CDC (Center for Disease Control) lead author Heather Jim, PhD. indicates, “In our observational study, we found people who found feelings of transcendence or meaningfulness or peace reported feeling the least physical problems.” Each of these items are part of her everyday life, so they provide comfort amid an otherwise stressful experience.
Medical facilities are offering complimentary therapies that stand side by side with mainstream practices.
We contemplated having her create a program for medical schools and treatment centers by which they would offer much-needed services that (equally as important as what the rest of the oncology team does) meet the patients where they are emotionally, physically, mentally and spiritually. The treatment rooms could have music piped in, or encourage recipients to bring their own to ease the effects of the chemicals flowing through their veins.
Reiki practitioners could offer their services during infusion and/or in surgery, since it has been shown to make a difference in pain and comfort levels. An assessment would include their spiritual practices and what they believe about the dis-ease that is impacting their lives. Do they fear it is a death sentence or a detour along the life path they thought they were traveling? Is it something from which they can learn and grow? Can they use it as a springboard for creating a new life?  Could it offer them freedoms they had not allowed themselves prior? What is their belief system vis- a ‘-vis the God of Their Understanding and the role of faith in healing?
Such an amenity could put the human in human services, knowing that any health care professional is one medical test away from being on the receiving end of treatment.
from World of Psychology http://ift.tt/2lQ4f5b via IFTTT
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