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neardiss · 1 year

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Highly Informative Details Regarding Fast Lean Pro Review

Fast Lean Pro is definitely a weight loss manufactured to facilitate women and men lose weight now without the need to abandon their best snacks. This device functions fooling the mind right into dreaming you will?with regards to fasting, which encourages a healthy progression referred to as autophagy in which supports nutritious weight management. These supplement also includes a mix of substances that should benefit improve electrical energy, advance ingestion, minimizing stomach ache. The information is made with all-natural items it is earned in north america within FDA-registered, GMP-certified capability. Just about every three positive plus six-bottle purchase of Fast Lean Pro provides you with a couple of free of cost e-books giving methods to obtain the most away from the unique dietary supplement. The most crucial compound inside of Fast Lean Pro is often a polyamine challenging recognized as Sukre, that your business situations are able to automatic systems wi-fi restoration. Polyamines usually are herbal elements that may play a role in a large number of complete body proceedings, which includes solar power increase combined with resolve. They've been by natural means taken by your whole body and also are very important for regulatory a person's stamina. Different kinds of biogenic polyamine heallth supplements can be bought avaiable for purchase, most notably putrescine and spermidine.

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juniperpublishers-gjpps · 3 years

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Spermidine for a Long, Dementia-Free Life?

Authored by Tsikas D

Abstract

Spermidine, N-(3-aminopropyl) butane-1,4-diamine, is an endogenous basic compound known for more than 90 years. The biosynthesis of spermidine, its pharmacological properties including distribution, metabolism and excretion have been thoroughly investigated. Spermidine and other polyamines have been early associated with growth and aging, and were found to stabilize various cellular and subcellular components including nucleic acids due to their polyvalent cationic structures. Polyamines including spermidine have been found at elevated circulating and urinary concentrations in a variety of diseases including cancer and psoriasis. Thus, decreasing the concentration of polyamines mainly by inhibiting their biosynthesis is regarded as a realistic therapeutical strategy. Yet, more recent studies suggest that exogenous spermidine exerts beneficial effects on the brain where it protects from age-induced memory impairment, protects the heart and extents lifespan.

Supplementation of the natural compound spermidine has emerged as an autophagy and mitophagy inducer in a mice model of aging and hypertension and lowered high blood pressure. In humans, high dietary spermidine intake was found to correlate with reduced blood pressure and decreased risk of cardiovascular disease and related death. Scientists in this area of research suggest that integration of spermidine in common diets may represent a cardio- and vascular-protective autophagy inducer in humans. The present article provides a brief review of the recent literature reporting on spermidine and takes the chance to make a first evaluation of the pharmacological potential of spermidine to reverse age-induced memory impairment, to protect the heart and to extent lifespan.

Keywords: Aging; Autophagy; Cancer; Dementia; Helicobacter pylori; Memory, to Mitophagy; Polyamines; Supplementation

Abbreviations: DMFO: α-difluoromethylornithine; GABR: Global Arginine Bioavailability Ratio; NOS: Nitric Oxide Synthase

Introduction

Spermidine, N-(3-aminopropyl) butane-1,4-diamine, is a low-molecular-mass organic base (C7H19N3, CAS 124-20-9) and belongs to the polyamine family which includes spermine and putrescine, the direct precursor of spermidine (Figure 1).At ambient temperature (22-25 °C) spermidine is a colorless liquid or a white powder. In biological samples, the two primary amine groups and the secondary amine group of spermidine are protonated so that the spermidine molecule is a polyvalent cation. Spermidine is a natural compound and widely distributed in plants, animals and humans. Scientific reports on spermidine and putrescine exist for more than 90 years, whereas articles on spermine appeared 25 years earlier (Table 1).

Spermidine is biosynthesized by microorganisms, plants and animals including humans [1-3]. Two possible biosynthetic pathways are illustrated in a simplified form in Figure 1. Hydrolysis of L-arginine by arginase yields L-ornithine which is decarboxylated by ornithine decarboxylase to form putrescine (butane-1,4-diamine or 1,4-diaminobutane). Putrescine can also be formed by hydrolysis of agmatine which is produced from L-arginine by the action of arginine decarboxylase. Putrescine is alkylated by the decarboxylated S-adenosyl-methionine which regularly serves as the major methyl (CH3) group donor for methyl transferases. Spermidine and other polyamines have been and are still subject of continuous scientific research from many different disciplines (Table 1). Spermidine's pharmacological properties including distribution, metabolism and excretion have been thoroughly investigated. A major fraction of injected spermidine is excreted in the urine [4]. Spermidine and other polyamines have been early and widely associated with growth (Table 1) and aging. They were found more than 50 years ago to stabilize various cellular and subcellular components including nucleic acids due to their polyvalent cationic structures.

Several analytical methods have been reported for the simultaneous measurement of spermidine, spermine and putrescine in human biological samples, including HPLC and GC-MS [5,6] and LC-MS/MS [7]. Polyamines including spermidine have been found at elevated circulating and urinary concentrations in a variety of diseases including cancer and psoriasis (Table 1). In plasma spermidine concentration was found to be 220 nM in healthy humans and 200-800 nM in cancer patients. Mean spermidine concentrations in urine were found to be also in the nM-range, e.g., 130 nM in healthy subjects, 186 nM in diabetic patients and 680 nM in patients with severe complications [7].

Measurement of elevated spermidine concentrations in subjects suffering from various diseases has early prompted research on developing drugs to inhibit polyamine biosynthesis. One of these drugs is α-difluoromethylornithine (DMFO) [2]. More recent studies suggest that spermidine supplementation may exert beneficial effects on the brain and the heart, and can even extent lifespan. A selection of these studies is provided in Table 2 [8-31] and is briefly reviewed and discussed in the section that follows. Escherichia coli (E. coli) has been very often associated with polyamines (Table 1). The pathogenic Helicobacter pylori (H. pylori) from subjects infected with the bacterium produces large amounts of spermidine and histamine in culture [32]. The potential implication of H. pylori-derived spermidine in diseases remains to be investigated. Spermidine is considered an inducer of autophagy. For recent reviews and commentaries to autophagy and longevity and underlying mechanisms see References [33-42]. For the polyamine content of food see the recent review by Kalač [43].

Discussion

Spermidine and other polyamines are biologically active compounds and have numerous biological activities in humans. More recent non-human studies suggest polyamines as potential candidates for diseases associated with autophagy or impairment of memory due to advanced age. Due to their pharmacological potential, their toxicity and health risks have been thoroughly investigated twenty years ago. Oral acute toxicity of spermidine was determined to be 600mg (4.1mmol)/kg body weight in Wistar rats, with the no-observed-adverse-effect being 83mg (0.57mmol)/kg body weight [43]. Pharmacokinetic data for spermidine and other polyamines in humans are very scarce and need to be generated in carefully performed studies. The toxicity and health risks data observed in animals and the polyamine concentrations measured in healthy and diseased subjects provide an approximate idea of the dose regimen for spermidine supplementation in humans.

Despite the long interest in polyamines, reference values and intervals have not been established thus far. Moreover, reported circulating and urinary polyamine concentrations vary considerably. As an example, plasma spermidine concentration lies between 0.2μM (healthy subjects) and 0.8μM (cancer patients) [6]. Spermidine concentration seems to be ten times higher in packed red blood cells (5-8μM) [43-45] compared to plasma, suggesting accumulation of spermidine in human erythrocytes. To our knowledge, there is only a single paper reporting on circulating spermidine concentration in healthy humans of both genders aging between 31 and 106 years. In the Group 1 (age range, 31-56 years) the spermidine median [95%CI interval] concentration was approximately 63 [48-100] pmol/mg whole blood proteins. In the Group 2 (age range, 60-80 years) the spermidine concentration was approximately 23 [20-30] pmol/mg protein, i.e., about three times lower than in Group 1. In the Group 3 (age range, 90-106 years) the spermidine concentration was approximately 70 [48-81] pmol/mg protein, i.e., even higher than in Group 1 [18]. This is a very important but also surprising observation and needs evaluation in forthcoming studies.

Eisenberg et al. [31] reported that "In humans, high levels of dietary spermidine, as assessed from food questionnaires, correlated with reduced blood pressure and a lower incidence of cardiovascular disease."

As the authors acknowledged in their paper, estimation of dietary spermidine intake on the basis of food-frequency questionnaires is an indirect method. In our opinion, this estimation is not eligible to draw far reaching conclusions that spermidine is the elixir for cardioprotection and lifespan extension. This must yet be demonstrated in further studies. In this context, we should remember that the mean daily dietary intake of spermidine in Western countries ranges between 7.9mg (54μmol) and 12.6 mg (87μmol) [43]. Even if these dietary spermidine amounts would be completely absorbed, the spermidine concentrations that would occur in blood and tissue would be not high enough to exert the reported effects in the majority of the studies in which spermidine was used mostly in the lower mM-range (Table 2). Eisenberg et al. [31] assumed that the blood pressure lowering effect of polyamines is presumably due to an increase of the bioavailability of L-arginine, but not data were reported about the nitric oxide (NO) synthesis from L-arginine. Based on the same thoughts and estimations stated above, dietary spermidine, and most likely other dietary polyamines, cannot considerably contribute to the global arginine bioavailability ratio (GABR), especially in regard to the about 1000 times higher dietary intake of L-arginine. Thus, food is likely to contribute to polyamines via bactericidal metabolism of exogenous L-arginine.

Therefore, if spermidine and other polyamines can indeed lower the blood pressure in humans, the underlying mechanisms are unlikely to be enhancement of the GABR. In mice, spermidine supplementation (3mM spermidine in drinking water for 4 weeks; 3mM in vitro in cultured aortic rings) has been reported to improve arterial aging in terms of a normalization aortic pulse waive velocity, endothelium-dependent dilation, autophagy, and even to reduce oxidative stress (based on nitrotyrosine measurement) in the older animals [46]. Unfortunately, in this paper no circulating concentrations were reported for spermidine and for the NO metabolites nitrite and nitrate. Very recently, the L-arginine metabolism has been investigated in rat vestibular nucleus and cerebellum. Measured biomarkers included arginine, citrulline, ornithine, glutamine, glutamate, GABA, spermidine, spermine, putrescine and agmatine and NOS activity by measuring the 3H-L-arginine to 3H-L-citrulline conversion rate [47].

This assay is associated with remarkable pitfalls, most notably with unspecificity, in tissue homogenates because of their capacity to produce and utilize L-citrulline by alternative pathways [48]. The study revealed that brain L-arginine metabolism is influenced by age. With regard to spermidine, age-related differences were found in the cerebellum but not in the vestibular nucleus complex of the rats (age, 4 v. 24 months), and not between middle-aged and aged rats (12 vs. 24 months). With minor exceptions [11,15], reported effects of exogenous spermidine have been observed at very high concentrations, mostly at 3mM (435mg/L) to 5mM (725mg/L). These concentrations are three and four orders of magnitude higher than spermidine concentrations found in plasma and red blood cells of humans, respectively. Although supplementation of high amounts of spermidine, putrescine or spermine is feasible from a pharmaceutical point of view, it has first to be demonstrated that supplementation of polyamines to reach concentrations that were turned out to be effective in flies, worms and small animals (mice and rats), is safe in humans.

Unfortunately, in the majority of the studies reported in the last decade, drug safety has not been implemented. Also, the potential formation of catabolic and metabolic reaction products of polyamines has not been considered at all. However, catabolism of polyamines produces many toxic compounds including H2O2 and aldehydes [43,49]. And last but not least important, spermidine can be nitrosated to N-nitrosospermidine which is further converted by cyclisation to N-nitrosopyrrolidine [50] which is classified as a possible carcinogen. Formation of nitrosopolyamines from polyamines and inorganic nitrite, that is abundantly present in human saliva, is favored under acidic conditions as they prevail in the stomach. In this context, a possible involvement of H. pylori which produces spermidine in large amounts [8] is worthy of investigation

A first research paper on spermidine and spermine in tissues of rats of increasing age revealed that the spermidine content decreased in all tissues with increasing age, with the fall being most marked during the first month of life [51]. The spermidine/ spermine molar ratio in the tissues was highest immediately after birth. In contrast to other tissues, in rat brain the spermidine/ spermine increased from 1.3 to 2.1 during the first 9 months. Similar results were found in liver and kidney of rats aged 1, 3, 6, 13 and 22 months [52].

In human brain, polyamines are heterogeneously distributed [53,54]. The highest spermidine levels were measured in white matter (20nmol/mg protein) and thalamus (9.3nmol/ mg protein) [29]. In contrast to rodents, spermidine levels in occipital cortex of neurologically normal human brain were found to increase markedly from birth, to reach maximal tissue content at the age of about 40 years and not to decrease up to senescence [53]. Spermidine tissue content was found to correlate positively with age from birth to adulthood (p=0.71, P<0.01, for day 1 to 50 years; p=0.40, P<0.01, for day 1 to 103 years). In contrast to spermidine, putrescine and spermine tissue concentrations were found to be independent of age. In older adults (mean age, 58-85 years), spermidine content in several brain regions was found to decrease with age [54]. Among the degenerative movement disorders investigated (Parkinson's disease, Huntington's disease to Progressive supra nuclear palsy), only spermidine putamen content was lower compared to healthy controls.

H. pylori has been declared as a definite gastric carcinogen [55]. The prevalence for H. pylori is about 50% around the world. This bacterium is considered to be responsible for about 90% of noncardia gastric cancer. The precise molecular and cellular mechanisms of gastric cancer development associated with H. pylori infection are still elusive. One possible mechanism could involve misregulation of p27 expression by H. pylori [55]. In cultures of this bacterium isolated from subjects infected with the H. pylori we measured large amounts of spermidine and histamine [8]. High circulating and urinary concentrations of polyamines are found in cancer patients [6]. One may therefore ask the question whether spermidine produced by H. pylori might be involved in gastric cancer. The potential implication of H. pylori-derived spermidine in diseases remains to be investigated. A very recent study revealed that spermidine, spermine and putrescine at very low concentrations (range, 8nM to 10|iM) induced proliferation and migration of certain cancer cells by up regulating among others ornithine decarboxylase and by down regulating p27 [56].

Conclusion

Since the fall of mankind, human beings strive for longevity in good physical and mental health. Can Science, the modern Prometheus, disclose us the secret of the Gods? Are natural polyamines the elixir for long life and against dementia? Might spermidine be the core-polyamine for a long and dementiafree life? Many sophisticated studies published in the last decade suggest that spermidine exerts beneficial effects in the cardiovascular system and in the brain, at least in yeast, flies, worms and small animals. Yet, in many respects human biology differs from that of rodents behave. With exception of isolated cells, where spermidine exerted remarkable effects at concentrations of the order of 20nM, too high spermidine concentrations have been supplied to achieve measurable biological effects.

Within a few years, there is already a general belief that spermidine is an inducer of autophagy and that this prolongs life. Spermidine, being an L-arginine metabolite, seems to be associated with NO which plays multiple roles in the renal, cardiovascular and central nervous systems. Yet, can the results observed in microorganisms and small animals be translated to man? Is high dietary spermidine intake a risk-free option for good physical and mental health? Data from human studies on spermidine are very rare, contradictory and not convincing for example with respect to the inverse correlation between spermidine and blood pressure or risk of cardiovascular disease and related death. In the past, observations from the use of many antioxidants at high concentrations in vitro and in vivo animal experiments raised the expectations for health-promotion in humans, but large clinical studies were very disappointing [57]. For the same reasons, most notably use of irrelevantly high concentrations/doses and disregard of health-risk effects, this may also happen to the use of spermidine and/or other polyamines as supplements. It’s a long way to Longevity!

#pharmacy #open access publishers #Juniper Publishers Address

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burningladywitch · 3 years

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Spermidine Supplement Benefits, Side effects, Dosage, Reviews

It is a no-brainer to live a long and healthy life. Everyone knows that eating a balanced diet with a workout routine can help you to be fit. However, there are several additional longevity options in the market nowadays known as supplements. Here, we are going to talk about a unique and worth trying supplement called spermidine. Well, the title spermidine sounds a bit suspicious to you? It was…

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#Spermidine

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meetpositivesblog · 5 years

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9 Proven Benefits of Semen that will Blow your Mind

Ah milk. The Dairy Council spends billions of dollars each year promoting the benefits of this cold, white drink. But have you ever wondered about the benefits of man milk? Yes, you read that correctly, man milk, aka semen.

As crazy as it sounds, semen has a multitude of benefits stemming from the minerals and nutrients it contains, and those seminal benefits can be passed directly on to you. That’s right; we did the research and now we’re here to present you with the facts.

Perhaps you’ve recently swallowed some baby gravy, or you enjoy drinking that man milk routinely. Regardless, you’re looking to find out if this creamy substance will provide you with anything more than a slightly sour stomach and a faint acidic aftertaste. So let’s take a dive into this sticky subject, and see the benefits that it offers.

Vaginal/Anal Intake

The vaginal and rectal linings are very absorbent, so either one is a viable route for soaking up the nutrients in your man’s spunk sauce.

Antidepressant

Semen contains quite a few components that have been studied to show anti-depressant qualities. One of these is nerve growth factor. Its primary responsibility in semen is to help relax the female so that the sperm can achieve its reproductive objective. It’s also been shown to be a vital hormone missing in the brains of those who suffer from Major Depressive Disorder. This means that increasing nerve growth factor would only prove to make people happier. Additionally, nerve growth factor has been found to be an anti-inflammatory as well as an antioxidant.

Antianxiety

Semen contains mood-enhancing compounds like oxytocin, progesterone, estrone, serotonin, and melatonin. Oxytocin is also known as the “cuddle hormone” because, when released, it makes people feel more affectionate and connected. Progesterone has been shown to have anti-anxiety characteristics. Estrone piggybacks on serotonin to help enhance moods, and melatonin helps relaxation occur.

Mood Enhancement

A study backed by the SUNY institute found that female college students who received baby batter on a regular basis were happier and less suicidal than those who didn’t. Researchers chalked this up to the mood-enhancing benefits of semen, however, they didn’t take into account any other factors, like a happy home life, being successful in school, or, I don’t know, getting raw D on the reg. Sounds like a pretty good place to be in life, and it sounds a little irresponsible to claim that the happiness of these women was directly dependent upon getting 20 ccs of white gold injected into them without taking any other factors into account. But what do I know? I’m no scientist. I’m just a chick writing a blog post about the benefits of man mayo.

Ingestion

The amount of Google searches for “eating cum” is astounding: a little under 10,000 for the past month, to be exact. In fact, this may have been the route you were thinking of when you initially clicked on this blog post. Lucky for you, we’ve got what you were looking for. Swallowing semen is the quickest way to get all of the benefits of your man’s baby juice, and think, he might even enjoy it too.

Longevity

We know this might be hard to swallow, but yes, semen can make you live longer. Spermidine (originally isolated from sperm, hence the name), when ingested, has been proven to dramatically increase the lifespan of animals by as much as 25 percent. In the same study, it was also found to prevent liver disease as well as liver cancer.

Cognitive Functioning

Nerve growth factor does a lot for the body. In addition to being an antidepressant, an anti-inflammatory, and an antioxidant, it’s also known to help stop the brain from aging. Nerve growth factor, which is very abundant in semen, is vital for maintaining the brain’s neurons. Neurons process and transmit information; they’re what make your brain work. Survival of these neurons is essential for you to have a working brain! Who knew that giving brain could affect your brain in such a positive way?

Nutritional Benefits

Have you recently taken a vitamin deficiency test (maybe on HealthLabs.com), and found that you were lacking in a few vital nutrients? Well get a spoon and ask your man for a plate of some nut butter, because semen is chock full of zinc, potassium, magnesium, calcium, and citrate. The nutrients get absorbed in your body like a less expensive vitamin shot (see ya later, Jamba Juice).

Topical

This might come as a surprise to you, but semen not only benefits the inside of your body but the outside as well. That’s right, with the amounts of zinc, vitamin c, and spermidine in your dude’s jizz, you could open up your own skincare line (this statement has not been evaluated by the FDA).

Teeth

Looking for an alternative, all-natural teeth whitening solution? Forget the charcoal; check out your man’s chubby. Although it’s not the white paste you’re used to putting on your toothbrush, semen has loads of zinc in it, which is a natural teeth whitener. Zinc’s seminal job is to aid the sperm’s survival. But that doesn’t mean that it can’t also aid the survival of your pearly whites.

Hair

Have you heard of a keratin treatment? Basically, you pay someone hundreds of dollars to put protein in your hair to make it stronger. Well, did you know that there’s a source of protein that you probably haven’t considered? Semen has over 200 different kinds of protein in it which can give your hair the strength and shine that it so desperately needs.

Semen also contains spermidine, which, when used on human scalps, has been shown to promote shaft elongation (LOL) as well as prolonged hair growth. Even though semen may be the one thing that you’ve actively tried to keep out of your hair, go ahead and consider this DIY hair treatment the next time you want to give your hair some life (get it?).

Skin

Spermidine is back, baby! In addition to increasing longevity and aiding in healthy hair, spermidine is an antioxidant and is great for the skin. It’s believed to smooth skin, lessen wrinkles, and even diminish acne. In fact, companies sell spermidine-derived facial cream for upwards of $200! If you’re not looking to spend that money, a money shot would be a cheaper and more natural alternative.

Injaculation

Let’s say you’re a man reading this blog post, and your partner doesn’t have a penis, or your penis-wielding partner isn’t willing to give you a nice, cold glass of man milk, so the only readily available source of semen is your own. You should be able to get some seminal rewards too! Sure, go ahead and smear it on your face and in your hair, but does the thought of drinking your own kool-aid or shooting it up your butt disgust and terrify you in ways that you’ve never felt before? Not to fear! There’s a way for you to utilize your own love juice, and it involves loving yourself.

Injaculation, or “retrograde ejaculation” is the process of releasing your semen inside your own body. When nearing close to an ejaculation, instead of allowing the splooge and all of its benefits land on an ungrateful sock, you release it in retrograde, or back inside of your body. It may sound painful or unnatural, but it’s not. Taoists have practiced injaculating for thousands of years, as well as certain sects of Buddhism, Hinduism, and even ancient Egyptians! So go on, show yourself some love.

Things to Remember

Now you know the different ways you can use that baby batter to your benefit, but there are a few things you should keep in mind before diving face-first into a vat of high fructose porn syrup.

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You can be allergic to semen. Before you go smearing it on your skin or guzzling it down like the thirsty thirst trap you are, know that there is an allergy called Human Seminal Plasma Protein Hypersensitivity. It can lead to an allergic reaction including itching, wheezing, hives, chest tightness, and difficulty breathing.

Though semen contains tons and tons of benefits, remember that it doesn’t come in huge quantities (~ 1 tsp). You would need to use a lot of semen to see most of the results. So, if you’re only using that baby formula for the benefits, you might be disappointed. Instead, we implore you to enjoy the nut butter for what it is and see the benefits as an added incentive.

Finally, and this is really, truly, the most important part: Make sure your source of semen is STD-free! You will do a lot more harm than good if you pour infected liquid gold all over your body. Let your man know that you’re interested in benefiting from his groin gravy, but he needs to get tested first.

*Remember, you can get STDs from oral sex, anal sex, and getting sex fluids in your eyes!*

And if you’re interested in learning more about the specific components of semen, check out our post on What’s Semen Made of.

Medically Reviewed by J. Frank Martin JR., MD on October 2, 2018

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hivknowledgeorg · 5 years

Text

9 Proven Benefits of Semen that will Blow your Mind

Vaginal/Anal Intake

The vaginal and rectal linings are very absorbent, so either one is a viable route for soaking up the nutrients in your man’s spunk sauce.

Antidepressant

Antianxiety

Mood Enhancement

Ingestion

Longevity

Cognitive Functioning

Nutritional Benefits

Topical

Teeth

Hair

Skin

Injaculation

Things to Remember

Now you know the different ways you can use that baby batter to your benefit, but there are a few things you should keep in mind before diving face-first into a vat of high fructose porn syrup.

Secure and Confidential STD testing services

The fastest results possbile – available in 1 to 2 days

GET TESTED TODAY

*Remember, you can get STDs from oral sex, anal sex, and getting sex fluids in your eyes!*

And if you’re interested in learning more about the specific components of semen, check out our post on What’s Semen Made of.

Medically Reviewed by J. Frank Martin JR., MD on October 2, 2018

from knowmystatus.life https://ift.tt/2pfpcZR via IFTTT

#IFTTT #knowmystatus.life

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herpesstdsymptoms · 5 years

Text

9 Proven Benefits of Semen that will Blow your Mind

Vaginal/Anal Intake

The vaginal and rectal linings are very absorbent, so either one is a viable route for soaking up the nutrients in your man’s spunk sauce.

Antidepressant

Antianxiety

Mood Enhancement

Ingestion

Longevity

Cognitive Functioning

Nutritional Benefits

Topical

Teeth

Hair

Skin

Injaculation

Things to Remember

Now you know the different ways you can use that baby batter to your benefit, but there are a few things you should keep in mind before diving face-first into a vat of high fructose porn syrup.

Secure and Confidential STD testing services

The fastest results possbile – available in 1 to 2 days

GET TESTED TODAY

*Remember, you can get STDs from oral sex, anal sex, and getting sex fluids in your eyes!*

And if you’re interested in learning more about the specific components of semen, check out our post on What’s Semen Made of.

Medically Reviewed by J. Frank Martin JR., MD on October 2, 2018

from knowmystatus.life https://ift.tt/2pfpcZR via IFTTT

#IFTTT #knowmystatus.life

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blog405095 · 4 months

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⛔ SPERMIDINE GENUINE PURITY 2024 REVIEW - REALLY WORKS?

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newhopediscoveries · 5 years

Text

9 Proven Benefits of Semen that will Blow your Mind

9 Proven Benefits of Semen that will Blow your Mind is courtesy of: www.knowmystatus.life

9 Proven Benefits of Semen that will Blow your Mind

Vaginal/Anal Intake

The vaginal and rectal linings are very absorbent, so either one is a viable route for soaking up the nutrients in your man’s spunk sauce.

Antidepressant

Antianxiety

Mood Enhancement

Ingestion

Longevity

Cognitive Functioning

Nutritional Benefits

Topical

Teeth

Hair

Skin

Injaculation

Things to Remember

Now you know the different ways you can use that baby batter to your benefit, but there are a few things you should keep in mind before diving face-first into a vat of high fructose porn syrup.

Secure and Confidential STD testing services

The fastest results possbile - available in 1 to 2 days

GET TESTED TODAY

*Remember, you can get STDs from oral sex, anal sex, and getting sex fluids in your eyes!*

And if you’re interested in learning more about the specific components of semen, check out our post on What’s Semen Made of.

Medically Reviewed by J. Frank Martin JR., MD on October 2, 2018

from Know My Status- STD Test https://ift.tt/33xxeft via IFTTT

#IFTTT #Know My Status- STD Test

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didanawisgi · 2 years

Link

#Spermidine

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12stepprogram1 · 5 years

Text

9 Proven Benefits of Semen that will Blow your Mind

9 Proven Benefits of Semen that will Blow your Mind is courtesy of: www.knowmystatus.life

9 Proven Benefits of Semen that will Blow your Mind

Vaginal/Anal Intake

The vaginal and rectal linings are very absorbent, so either one is a viable route for soaking up the nutrients in your man’s spunk sauce.

Antidepressant

Antianxiety

Mood Enhancement

Ingestion

Longevity

Cognitive Functioning

Nutritional Benefits

Topical

Teeth

Hair

Skin

Injaculation

Things to Remember

Now you know the different ways you can use that baby batter to your benefit, but there are a few things you should keep in mind before diving face-first into a vat of high fructose porn syrup.

Secure and Confidential STD testing services

The fastest results possbile - available in 1 to 2 days

GET TESTED TODAY

*Remember, you can get STDs from oral sex, anal sex, and getting sex fluids in your eyes!*

And if you’re interested in learning more about the specific components of semen, check out our post on What’s Semen Made of.

Medically Reviewed by J. Frank Martin JR., MD on October 2, 2018

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cclpharmaco · 5 years

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9 Proven Benefits of Semen that will Blow your Mind

9 Proven Benefits of Semen that will Blow your Mind is courtesy of: www.knowmystatus.life

9 Proven Benefits of Semen that will Blow your Mind

Vaginal/Anal Intake

The vaginal and rectal linings are very absorbent, so either one is a viable route for soaking up the nutrients in your man’s spunk sauce.

Antidepressant

Antianxiety

Mood Enhancement

Ingestion

Longevity

Cognitive Functioning

Nutritional Benefits

Topical

Teeth

Hair

Skin

Injaculation

Things to Remember

Now you know the different ways you can use that baby batter to your benefit, but there are a few things you should keep in mind before diving face-first into a vat of high fructose porn syrup.

Secure and Confidential STD testing services

The fastest results possbile - available in 1 to 2 days

GET TESTED TODAY

*Remember, you can get STDs from oral sex, anal sex, and getting sex fluids in your eyes!*

And if you’re interested in learning more about the specific components of semen, check out our post on What’s Semen Made of.

Medically Reviewed by J. Frank Martin JR., MD on October 2, 2018

from Know My Status- STD Test https://ift.tt/33xxeft via IFTTT

#IFTTT #Know My Status- STD Test

0 notes