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budandtender · 6 months
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Understanding the Role of Endocannabinoids in Psoriasis Regulation
World Psoriasis Day October 29th
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Introduction
World Psoriasis Day is a global event that shines a light on psoriasis, a chronic autoimmune condition that causes red, scaly patches to appear on the skin. It's an opportunity to educate and raise awareness about this often misunderstood disease. In this article, we'll delve into how endocannabinoids can regulate psoriasis, providing a unique perspective on the disease's underlying mechanisms.
Understanding Endocannabinoids
Endocannabinoids are naturally occurring compounds within our bodies that interact with the endocannabinoid system (ECS). The ECS is a complex cell-signalling system that plays a key role in regulating a range of functions and processes, including immune response, pain, mood, and more.
The two primary endocannabinoids are anandamide (AEA) and 2-arachidonoylglycerol (2-AG). These molecules bind to CB1 and CB2 receptors found throughout the body, triggering various physiological responses. Interestingly, research has indicated that these endocannabinoids and their receptors may play a significant role in managing skin health and diseases such as psoriasis.
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Endocannabinoids and Skin Health
Our skin is not just a barrier protecting us from the outside world; it's also a complex organ with its own ECS. This system plays a crucial role in maintaining skin homeostasis – the balance of cell growth and death. In conditions like psoriasis, this balance is disrupted, leading to an overproduction of skin cells.
Research has shown that endocannabinoids can influence several key aspects of skin health. They can regulate skin cell proliferation and differentiation, immune response, and inflammation - all critical factors in psoriasis.
Endocannabinoids and Psoriasis Regulation
Psoriasis is characterised by an overactive immune response, leading to inflammation and rapid skin cell growth. The role of endocannabinoids in psoriasis regulation primarily revolves around their anti-inflammatory and immunomodulatory properties.
Studies have shown that endocannabinoids can reduce inflammation by downregulating the production of pro-inflammatory cytokines, proteins that promote inflammation. This could potentially help manage the chronic inflammation seen in psoriasis.
Moreover, endocannabinoids can also modulate the immune response. They can inhibit the overactive immune cells responsible for the rapid skin cell growth in psoriasis, helping to restore balance in the skin's ecosystem.
Research also suggests that people with psoriasis may have an impaired endocannabinoid system, with lower levels of endocannabinoids in their skin. This could potentially contribute to the disease's development and progression, highlighting the potential therapeutic value of targeting this system.
Conclusion
While the relationship between endocannabinoids and psoriasis is complex and still not fully understood, current research indicates a promising role for these molecules in regulating the disease. By modulating inflammation and immune response, endocannabinoids could potentially help manage psoriasis symptoms and improve skin health.
However, it's important to note that more research is needed to fully understand the mechanisms involved and how best to harness the power of endocannabinoids for psoriasis treatment. As we celebrate World Psoriasis Day, let's also celebrate the ongoing research and advancements that bring us closer to understanding and effectively managing this challenging condition.
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neodermatologist · 20 days
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drathinatraianou · 2 months
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Η ψωρίαση είναι μια δερματολογική πάθηση που επηρεάζει εκατομμύρια ανθρώπους παγκοσμίως. Με τη σωστή διάγνωση και θεραπεία, μπορούμε να διαχειριστούμε τα συμπτώματα και να βελτιώσουμε την αυτοπεποίθησή σας και την ποιότητα ζωής. Επικοινωνήστε μαζί μας για να μάθετε περισσότερα για τη διαχείριση της ψωρίασης.
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zivaclinic · 5 months
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Don’t let Psoriasis bring you down. Let us help you get rid of it Psoriasis is a chronic autoimmune condition presenting with Red patches on the skin with Silvery-white scales over it. It can affect Skin, Scalp, Nails and Joints. It is not contagious. It can be triggered by Infections, Stress, Dry Skin and Cold Weather. Treatment options for psoriasis include Oral and Topical medications, and Biologic Injections. For further queries Contact Ziva Skin & Hair Center. Book an appointment @ 096117 77256
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jnh-lifestyles-saunas · 9 months
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"Infrared saunas are a complementary treatment for psoriasis. There is also some evidence that certain types of infrared light, such as NIR, may help reduce pain and inflammation and promote skin healing. It is important to consult a dermatologist with experience in treating psoriasis and to discuss infrared light therapy with them before trying it."--medicalnewstoday
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livewellclinics · 9 months
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Derma-Clear provides skin specific support to patients experiencing ongoing skin disorders including eczema, psoriasis and acne.
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theradicalscholar · 10 months
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🌿🌸 Welcome to The Radical Scholar, where we explore comprehensive information on psoriasis and share home remedies to help alleviate its symptoms naturally.
Psoriasis, a chronic autoimmune disease affecting millions worldwide, can be managed through a combination of medical treatments and complementary home remedies.
Discover a range of natural solutions, from soothing topical remedies to dietary adjustments and lifestyle changes, that can support your psoriasis management plan.
Remember to consult with healthcare professionals and find a balance that works best for you.
Don't forget to sign up for our newsletter and delve into our blog series, "Decoding Psoriasis: Understanding the Complexity of a Chronic Skin Condition," for a deeper understanding.
Let's embark on this journey towards effective psoriasis management together! 💚✨
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drpraneethclinic · 11 months
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Want to cure Your Psoriasis
Phototherapy Treatment is available at Dr. Praneeth Skin Hair Laser Clinic 
Visit for Know More - www.drpraneethclinic.com
Call For Inquiries - 9704946534/040-48553939
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sejshomeocare · 1 year
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How to cure Scalp Psoriasis Never Again 100% Best Treatment
In Psoriasis, you get dry, scaly, pink coloured crusty lesions on your skin. It’s an autoimmune disease so the main cause cannot be determined. It happens when your immune system starts attacking your own tissues of body. This disease is also associated with relapses and remissions.
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https://sejshomeocare.com/cure-scalp-psoriasis-best-treatment-never-again/ Visit: https://sejshomeocare.com More Info: +91 99876 34844
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daddysprncss666 · 1 year
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happiest day of my life- my psoriasis medication finally got approved by my insurance!!💓✨ #psoriasis #psoriasisawareness #chronicillness (at Erie County, Pennsylvania) https://www.instagram.com/p/Cm9f3LCrfCk_WiKn8z8UPjAUDi37pPYq45hek80/?igshid=NGJjMDIxMWI=
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budandtender · 9 months
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Decoding the Enigma: Endocannabinoids as Pioneers in Psoriasis Management
Psoriasis Awareness Month August 2023
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Introduction
Psoriasis is a chronic, inflammatory skin condition that affects millions of people worldwide. It manifests as red, scaly patches on the skin, which can be itchy and painful. Although the exact cause of psoriasis is not yet fully understood, researchers believe that it is an autoimmune disorder, wherein the immune system mistakenly attacks healthy skin cells. Over the years, numerous treatments have been developed to manage the symptoms of psoriasis, but there is still no known cure for the condition. In recent years, scientists have started to explore the role of endocannabinoids in regulating psoriasis, opening up new avenues for potential therapies.
Understanding Endocannabinoids
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Endocannabinoids are naturally occurring compounds found within our bodies that interact with the endocannabinoid system (ECS). The ECS is a complex cell-signalling system that plays a crucial role in maintaining homeostasis – the balance of various physiological processes. It is involved in regulating a wide range of functions, including mood, appetite, sleep, pain perception, and immune response.
The two primary endocannabinoids identified so far are anandamide and 2-arachidonoylglycerol (2-AG). These molecules bind to cannabinoid receptors (CB1 and CB2) located throughout the body, influencing the activity of various cells and tissues. While the ECS is primarily associated with the effects of cannabis, its role extends far beyond the plant and its derivatives.
Endocannabinoids and Psoriasis
Recent research has indicated that the endocannabinoid system may play a significant role in regulating skin health and function. Studies have shown that both CB1 and CB2 receptors are present in skin cells, including keratinocytes, sebocytes, and immune cells. This suggests that endocannabinoids could potentially influence skin inflammation, cell proliferation, and differentiation – all of which are crucial factors in the development of psoriasis.
In psoriasis, an overactive immune response leads to the rapid growth and accumulation of skin cells, causing the characteristic scaly patches. Researchers have found that endocannabinoids can modulate immune cell activity and reduce inflammation by interacting with CB1 and CB2 receptors. This may help to alleviate the symptoms of psoriasis by dampening the immune response and promoting a healthier balance of skin cell production.
Moreover, endocannabinoids have been shown to regulate the growth and differentiation of keratinocytes – the primary cell type involved in psoriasis. By influencing the activity of these cells, endocannabinoids may help to normalize skin cell turnover and prevent the buildup of excess cells.
Future Perspectives
While the research on endocannabinoids and psoriasis is still in its early stages, these findings offer promising insights into potential new treatment avenues. By better understanding the role of the endocannabinoid system in skin health and disease, researchers may be able to develop targeted therapies that harness the power of our body's natural compounds to manage psoriasis and other inflammatory skin conditions.
It is essential to note that the focus of this article is on endocannabinoids and their potential role in regulating psoriasis, not on the medical uses of CBD or other cannabinoids derived from cannabis. Further research is needed to fully understand the complex interactions between endocannabinoids and the pathogenesis of psoriasis, as well as to develop safe and effective therapies based on these findings.
Conclusion
The discovery of the endocannabinoid system's involvement in skin health has opened up new possibilities for understanding and treating psoriasis. While more research is needed to fully comprehend the mechanisms at play, the preliminary findings offer hope for those suffering from this chronic and often debilitating condition. By exploring the role of endocannabinoids in regulating psoriasis, scientists may be able to develop innovative therapies that work with our body's natural systems to promote healthier skin and improved quality of life for patients.
If you wish to help support and raise awareness about Psoriasis, you can donate here to the Psoriasis Association UK.
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aajkaakhbaar · 2 years
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What is psoriasis and how can it be treated
Psoriasis is a chronic condition that causes red, scaly patches on the skin. It’s often compared to having sandpaper skin because it can be very uncomfortable and painful. The disease affects more than three million people in the United States alone, making it one of the most common forms of arthritis. Although psoriasis has no cure, there are treatments available to help reduce symptoms and prevent flare-ups; however, they may not work for everyone who suffers from this disease. In this article, we'll discuss what psoriasis is and how it can be treated with both conventional medicines as well as alternative methods such as natural remedies.
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siukhapha-hospital · 2 years
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Busting Myths Vitiligo
Vitiligo is a long-term non-infectious skin condition characterized by patches of the skin losing their pigment, in other words, it impacts melanin production. Read more
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livewellclinics · 9 months
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The Naturopathic approach to managing Psoriasis aims to address the condition holistically supporting not only skin healing but immune system function and overall health for long-term results.
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theradicalscholar · 10 months
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Living with psoriasis can present unique challenges, but remember, you are not alone.
In the final part of our blog series, we explore empowerment and support for individuals with psoriasis.
Building a strong support network, engaging in advocacy, practicing self-care, and promoting inclusivity are key.
Let's create a compassionate society that celebrates resilience and strength.
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marybrownnaturals · 1 year
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Introducing 100% Natural Licorice Root Liquid Shampoo, Face and Body Wash by Bare Beauty Naturals
No one knows exactly what psoriasis is. It isn't an infection or an allergic reaction, nor is it contagious. But somehow it disrupts the growth-replacement cycle of skin and hair cells.
Clinical evidence suggests that using licorice root for 4 weeks seems to improve skin psoriasis as well as blackhead/whitehead/acne symptoms. Best Shampoo for Greasy Hair & Dandruff.
Licorice Root is also said to nourish the Root Chakra, responsible for your sense of safety and security on this earthly journey.
Purchase online at https://www.barebeautynaturals.com or check the link on our Instagram Bio!
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