#insulin-dependent diabetes | Explore Tumblr Posts and Blogs

wellhealthhub · 10 months

Text

Understanding the Distinctions Between Type 1 and Type 3c Diabetes: A Comprehensive Analysis

Diabetes, an intricate ensemble of metabolic disorders, engenders persistent elevations in blood sugar levels over protracted durations. Among the variegated tapestry of diabetes classifications, Type 1 and Type 3c diabetes conspicuously manifest themselves, distinguished by their unique etiologies, symptomologies, and therapeutic approaches. The present article endeavors to navigate the…

View On WordPress

1 note · View note

ghostfilles · 2 years

Text

i am so fucking SICK of the “jokes” about how all diabetics are fat or how every fat person on earth has diabetes/will get diabetes. that’s not how it fucking works. diabetes is not SOLELY a fat person disease and the next crusty boring streamer to make that joke can get fucked and i wish you a very deplatformed

diabetes is not caused by being fat -- it’s caused by poor dietary choices. my uncle was rail thin and had wildly uncontrolled diabetes due to his poor diet/massive sugar intake. the reason it’s connected to being a “fat” disease is because a poor diet causes weight gain a lot of the times but diabetes is NOT conditioned on being fucking fat. there are plenty of people who are overweight that don’t have it. just. god. people need to shut the fuck up.

#cody.txt #i'm diabetic AND fat i'm not diabetic because i'm fat #i'm diabetic bc it's extremely genetic on both sides of my family #my wife knows a girl who's thin as a rail and is insulin dependent #type 1 diabetics especially aren't at all connected to their weight especially KIDS who are BORN with it what the fuck #god i'm so heated #fatphobia tw

9 notes · View notes

wellextol · 3 months

Text

Glucodyn: The Comprehensive Blend Glucodyn is a supplement that combines a carefully selected array of vitamins and nutrients to target the unique needs of individuals dealing with Type 2 Diabetes and insulin resistance.

0 notes

anotherlesbiandad · 4 months

Note

This is a longshot, would you be willing to help me get my insulin? I'm down to my last pen and its pretty much close to being empty.Nt asking for much only need $370 rn to save my blood sugar. please help me with a small donation or share, reblog any help can save my life.Please help & Blessings ❤

hey! so i can't help money wise right now, but i'm gonna answer this publicly in the hopes that someone will see and help

#on a more personal note #my dad is an insulin dependent type 1 diabetic #and the insulin prices are spiking like crazy right now #even more than usual #i truly believe that it's ridiculous and awful that this is something that people have to pay for at all #let alone this much

0 notes

aravind09 · 8 months

Text

symptoms of diabetes type 2 in adults

Diabetes is on the ascent overall and is a serious, deep rooted sickness that can prompt coronary illness, stroke, and enduring nerve, eye, and foot issues. We should examine a couple of kinds of diabetes and their disparities. What is diabetes, and where does it emerge from? Insulin is a chemical that controls how much glucose in your body and is delivered by an organ known as the pancreas. You can foster diabetes, a problem set apart by strangely high blood glucose or sugar levels, when your body produces lacking insulin or when insulin doesn't work as expected in your body.

#type 2 diabetes mellitus #obesity and diabetes #insulin dependent diabetes mellitus

0 notes

cheekios · 14 days

Text

Last Cartridge of Insulin

This is an URGENT REQUEST as I cannot go a day without insulin. Currently I am unemployed through no fault of my own. I do not have insurance so I will have to use GoodRx. My insulin is called Afrezza. It costs around $450-$490 depending on the pharmacy I go to.

Goal: $450

CA: $HushEmu

PP: [email protected]

Currently I cannot drive because my only pair of perscription glasses are broken. So I will also need help with ubers. Please.

I’d like to stress that not taking insulin daily is deadly. This is a medical emergency. Begging for this request to be filled.

Informative read:

https://www.healthcentral.com/condition/type-1-diabetes/how-long-can-a-diabetic-go-without-insulin

2K notes · View notes

rockoblanco · 1 year

Text

lol talking to a family friend & told him im trying to get diagnosed for adhd bcs the more i learn about it and treatment options the more hope I have that I can have some semblance of a better life for myself and instead of being like “good for you” he’s playing at the “oh but narcotics are stimulants and you’ll get a dependency and you can’t trust big pharma and it’s not worth it.” Like you’re not entirely wrong but you’re incredibly narrow minded & don’t know what you’re talking about if you think that the only medication for adhd are stimulants (there are other drugs that aren’t stimulants that can help to clinically “normalize” an adhd brain), and also like how dare you try and tell me that trying to build a better future for myself where i don’t feel like dying everyday isn’t worth the risk lmaoooooooooo

#soooo easy for someone to say who can wake up when they want to & doesn’t have emotional disregulation that makes them want to physically #harm themselves multiple times a day lol #as well as being able to pay attention to any singular thing for more than 2 seconds unless my livelihood depends on it LMAOO #also like im not stupid this information is from the leading ass researcher of adhd whose been studying this ish for DECADES #he said himself you wouldn’t withdraw insulin from a diabetic patient #it’s the same thing with adhd your brain cannot do the jobs it needs to do so why would you prevent yourself #from being able to do them if you can ?#like I didn’t pull this ish out of my ass but he sure did lmaoooo im big mad he’s so dumb sometimes #ranting im sorry I will def delete this just need to vent #search up Dr. Russell Barkley #& listen to his episode on Ologies - Attention-Deficit Neuropsychology #honestly kind of changed my life & made me feel seen for the first time in kind of forever

1 note · View note

cripplecharacters · 4 days

Text

Disabilities that You Should Consider Representing in Your Writing More… part 1

[large text: Disabilities that You Should Consider Representing in Your Writing More… part 1]

While all disabilities are underrepresented in basically all sorts of media, it’s hard to not notice the trend in what disabilities make up the majority of representation. It’s especially visible when having a blog like this, where we can see what disabilities writers even consider including in their writing, and which ones never come up.

One in four people are disabled. With eight billion people alive it means there’s a lot of disabled people, and a lot of reasons why they are disabled in the first place - but this diversity is rarely represented, even on this blog, and anyone who has been following for a while has probably noticed that fact.

To be blunt: there are disabilities other than “amputee” and “(otherwise invisibly disabled) mobility aid user”. Does that mean that it’s wrong to write either of those? Of course not, and we don’t want to imply that it is. Does it mean that when you are deciding on what to give your character, you should think beyond just those two? Absolutely. Disability is a spectrum with thousands of things in it - don’t limit yourself for no reason and embrace the diversity that’s built into it instead.

This is, simply, a list of common disabilities. This is just a few of them, as this is part one of presumably many (or, at least three as of right now). By “common” we rather arbitrarily decided on “~1% or more” - so at least 1 in 100 people has the disabilities below, which is a lot. Featuring!: links that you should click, sources of the % that are mostly just medical reports and might be hard to read, and quick, very non-exhaustive explanations to give you a basic idea of what these are.

Intellectual disability (about 1.5%) Intellectual disability is a condition we have written about at length before. It’s a developmental disability that affects things such as conceptualization, language, problem-solving, or social and self-care skills. ID can exist on its own or be a part of another condition, like Down Syndrome, Congenital Iodine Deficiency, or Fetal Alcohol Spectrum Disorders. This post covers a lot of basic information that you might need. We have an intellectual disability tag that you can look through!

Cancer survivors (5.4% in the US, about 0.55% worldwide) A cancer survivor is a pretty self-explanatory term. There is a lot of types of cancer and some of them are very common while others are very rare, which makes this a very diverse category. Cancers also have different survival rates. While not every survivor will have disabling symptoms, they definitely happen. Most of the long-term side effects are related to chemotherapy, radiation, and other medication, especially if they happened in children. They can include all sorts of organ damage, osteoporosis, cognitive problems, sensory disabilities, infertility, and increased rate of other cancers. Other effects include removal of the affected area, such as an eye, a spleen, breasts, or the thyroid gland, each of which will have different outcomes. Cancer, and cancer treatments, can also result in PTSD.

Diabetes (about 8.5%, ~95% of that are type 2) Diabetes is a group of endocrine conditions that cause hyperglycemia (high blood sugar) for various reasons depending on the type. The vast majority of people have type 2 diabetes, which can cause fatigue, poor healing, or feeling thirsty or hungry. A diabetic person will use insulin when needed to help manage their blood sugar levels. There are many complications related to diabetes, from neuropathy, to retinopathy, and chronic kidney disease, and there's a lot of disabilities that coexist with diabetes in general! You might want to check out the #how to write type 1 diabetes tag by @type1diabetesinfandom!

Disabling vision loss (about 7.5%) Blindness and low vision are a spectrum, ranging from total blindness (around 10% of legally blind people) to mild visual impairment. Blindness can be caused by countless things, but cataracts, refractive errors, and glaucoma are the most common. While cataracts cause the person to have a clouded pupil (not the whole eye!) blind eyes usually look average, with strabismus or nystagmus being exceptions to that fairly often (but not always). Trauma isn't a common cause of blindness, and accidents are overrepresented in fiction. A blind person can use a white cane, a guide dog or horse, or both. Assistive solutions are important here, such as Braille, screenreaders, or magnifying glasses. We have a blindness tag that you can look through, and you might want to check out @blindbeta and @mimzy-writing-online.

Psoriasis (about 2-4%) Psoriasis is a chronic skin condition with multiple subtypes; it can cause intense itching, pain, and general discomfort, and often carries social stigma. It’s an autoimmune and non-contagious disability that affects the skin cells, resulting in raised patches of flaky skin covered with scales. It often (30%) leads to a related condition, psoriatic arthritis, which causes joint pain, tenderness, and fatigue, among other things.

Stroke survivors (0.5-1%) A stroke survivor is a person who has survived any kind of stroke (ischemic, hemorrhagic, etc.). While the specific symptoms often depend on the exact location on where the stroke happened, signs such as hemiplegia, slurred speech, vision problems, and cognitive changes are common in most survivors to some degree. When someone has a stroke as a baby, or before they are born, it can result in cerebral palsy, epilepsy, and other disabilities. We have a brain injury tag that you can look through!

Noonan Syndrome (about 0.1-1% - mild is 1%, severe 0.1%) Noonan Syndrome is a disability that is almost never mentioned in any context, but certainly not around the topic of writing disabled characters. It’s a congenital condition that can cause cardiomyopathy, chronic joint pain, hypermobility, short stature, facial differences such as ptosis, autism, and various lymphatic problems among other things. Some people with Noonan Syndrome might use mobility aids to help with their joint pain.

Hyperthyroidism (about 1.2%) Hyperthyroidism is a condition of the endocrine system caused by hormone overproduction that affects metabolism. It often results in irritability, weight loss, heat intolerance, tremors, mood swings, or insomnia. Undertreated hyperthyroidism has a rare, but extremely dangerous side effect associated with it called a thyroid storm, which can be fatal if untreated.

Hypothyroidism (>5%) Hypothyroidism is an endocrine condition just as hyperthyroidism is, and it causes somewhat opposite symptoms. Due to not producing enough thyroid hormones, it often causes fatigue, depression, hair loss, weight gain, and a frequent feeling of being cold. It’s often comorbid with other autoimmune disabilities, e.g. vitiligo, chronic autoimmune gastritis, and rheumatoid arthritis. Extreme hypothyroidism can also be potentially fatal because of a condition known as Myxedema coma (or “crisis”), which is also rare.

Deafblindness (about 0.2-2%) Being DeafBlind is often considered to be an extremely rare disability, but that’s not really the case. DeafBlindness on its own isn’t a diagnosis - it can be caused by a wide range of things, with CHARGE syndrome (congenital), Usher syndrome (born deaf, becomes blind later in life), congenital rubella, and age-related deafness and blindness being some of the most common reasons. DeafBlindness is a wide spectrum, the vast majority of DeafBlind people aren’t fully blind and deaf, and they can use various ways of communication. Some of these could be sign language (tactile or not), protactile, the deafblind manual, oral speech (aided by hearing aids or not), the Lorm alphabet, and more. You can learn more about assistive devices here! Despite what various media like to tell you, being DeafBlind isn’t a death sentence, and the DeafBlind community and culture are alive and thriving - especially since the start of the protactile movement. We have a DeafBlindness tag that you can look through!

It’s probably worth mentioning that we have received little to no asks in general for almost all the disabilities above, and it’s certainly not due to what mods answer for - majority of our inbox is amputee-related, and we haven’t had mods that answer those for somewhere around four years now. Our best guess is that writers don’t realize how many options they have and just end up going for the same things over and over.

Only representing “cool” disabilities that are “not too much while having a particular look/aura/drama associated” isn’t what you should aim for. Disabled people just exist, and all of us deserve to be represented, including those whose disabilities aren’t your typical “cool design” or “character inspo”. Sometimes we are just regular people, with disabilities that are “boring” or “too much”, and don’t make for useful plot points.

mod Sasza (with huge thank yous to mod Sparrow, Rot, and Virus for their contributions with research and data!)

#mod sasza #disabled character ideas #writing guide #writing resources #writing help #writing advice #writeblr

750 notes · View notes

comicaurora · 4 months

Note

Sorry to drop a hella irl-political question on your mostly webcomic blog, but have you/any of the OSP gang heard of/been participating in the week-long strike for palestine that's been (presumably) all over tumblr/the internet?

For some background info: Following the attack on Oct. 7th by the hamas militant group (a terrorist org. Or resistance group, depending who you ask), the state of israel (which is practically a mass colonial settlement on Palestinian land since '48) has taken the attack as an excuse to indiscriminately bomb the homes of thousands if not millions of homes while forcebly displacing almost all of the ~2.3 million people crammed in the gaza strip with no escape.

'Israel' has also tightened it's blockade on the strip of land such that a growing majority of people there are experiencing catastrophic starvation, disease from sewage-infested drinking water (as water aid is too scarce). Soon even deaths by preventable causes such as diabetes will occur since insulin pens for children have been blocked from entering by israel, who controls gaza's borders, water, power, food supplies, and shoreline. Civilians in Gaza are very frequently and indiscriminately killed often in places they were told were safe zones to evacuate to. It's agreed upon by both experts and laymen worldwide that what is happening (and has BEEN happening before Oct.7th) is nothing short of genocide.

In the occupied Palestinian west bank, where there is no hamas whatsoever to use as an excuse, Palestinians are still arrested without a fair trial for years, abused, prevented from using certain roads, shot, and often straight-up have their houses stolen by armed or military-backed israeli settlers (many of whom have no ancestral connection to the land at all) in a system often compared to or outright stated to be apartheid.

Very recently, a journalist in Gaza by the name of Bisan Owda called for a strike from January 21st to January 28th. The conditions of the strike can be paraphrased as:

Cease all unnecessary purchases or payments, avoid generating ad revenue when possible

Do not go to work or school if you can possibly avoid it

Pay for things only in cash if you must

Use social media exclusively to flood the internet with palestinian voices and resources about the ongoing genocide against the palestinian people

Attend protests if you can

Be visible.

It's the 26th now, but joining late would be far better than to not join at all and stay silent.

I figured I'd ask since since OSP has covered various topics about history and/or politics and we're kinda watching some awful history unfolding, the kind of history where neutrality doesn't really work and a side needs to be taken.

Opinions? (Sorry if I'm coming across as condescending! I just really want my favorite blogs to be aware and take a stance rather than being silent hhhghf)

Okay, here's my answer.

OSP has been supporting calls for a ceasefire for months, and we were fundraising in direct support of it via Doctors Without Borders all through November and December. Total, we raised over $30,000. If we include the UNICEF fundraiser we ran on the Spider-Man streams, the total is over $40,000.

During our charity livestreams, we have made our positions clear – we support a ceasefire, Israel is perpetuating settler-colonialist violence and has been for decades, Hamas is a terrorist organization that endangers Israelis and Palestinians alike, the innocent people of both Palestine and Israel deserve safety and peace. We concluded that the best thing we could do under the circumstances was empower those who are in a real position to actually help by providing funding for their work. We believe this is significantly more beneficial than adding Another Angry Internet Post to the pile of insular outrage on Internet Land. Fundraising for the organizations with boots on the ground feels like it does a lot more good than being loud online for the benefit of other online people.

This is not the first time I've heard reference to the strike, but it is the first time I've seen the parameters of the strike laid out, which to me indicates that it wasn't spread as widely or effectively as it could've been.

I understand and appreciate why you sent this ask, but your premise worries me. I know this may surprise and startle us denizens of the internet, but being extremely loud on the internet is not the only or the most effective form of activism, and people not being extremely loud on the internet with every account they have is not the same thing as silent complicity in war crimes, and people acting like those two things are the same thing has been unbelievably frustrating to watch.

If we act like everything is a binary moral choice between "scream your loudest, most angry opinions online every time you feel angry about them" and "not doing that is literally the same thing as participating in genocide", we are creating a very strong pressure to flood the internet with our angriest, most unformed thoughts, lest we be branded as complicit in war crimes. Social media sites live and die on engagement, hence why twitter has rapidly trended towards doomscrolling and encouraging inflammatory clickbait - angry shouty people are traffic and traffic is money. The cynical part of me is utterly unsurprised that social media encourages the idea that the only true form of activism is being loud on social media.

It sounds like you had the feeling that sending me this ask was weird and a boundary overstep, and you were correct. My platform is not world-changing or in any way politically powerful beyond our ability to create charity fundraisers for causes we believe in, and we are doing what we can to help in the tiny ways that we can from halfway across the world, from a position of absolutely zero political weight beyond emailing our representatives. You are just asking me to also shout about it online loudly enough that I measure up to an artificial loudness metric, because my existing shouting was not already loud or omnipresent enough.

You are not entitled to know every thought in my head or every action I take in my life. I am not online to perform outrage and live up to an arbitrary moral standard of Shouting Enough. I am especially not online on my fantasy webcomic blog to do those things. Please understand that what you see of me is what I choose to share, and I am under no obligation, moral or otherwise, to share more.

#asks #not aurora #taking a big risk putting this on the reading comprehension website #turned off reblogs just so I don't stress all night

674 notes · View notes

wellhealthhub · 10 months

Text

Comprehensive Guide to Diabetes Medications

Welcome to this comprehensive guide on diabetes medications, where we shall explore the intricacies of various pharmacological agents that aid in effectively managing blood sugar levels and fostering a healthier life with diabetes. 1. Insulin Injections Insulin, a paramount hormone synthesized by the pancreas, orchestrates the regulation of blood sugar levels, a critical facet for individuals…

View On WordPress

0 notes

12percentspider · 2 months

Text

Info time: Diabetes and related issues [this is long but I highly suggest reading]

Do you ever see something and you go "that doesn't sound right, but I don't know enough about diabetes to dispute it"? Well, I can help you there. I can help you know enough about diabetes to dispute it if need be. Especially because well, there are seemingly a lot of scams going around where people claim to be diabetic [in my experience it's maybe 3 scammers that just remake] and the information is not very correct in most cases. Not to mention this type of scam pisses me off because I am in fact diabetic, and not only are people preying off of others' lack of information about the chronic condition, but it's also trivializing a serious lifelong condition that can be fatal. If you have now or have lost a loved one to diabetes complications, you are already aware of how dangerous it can be as well as how dangerous misinformation is as well.

What is diabetes? Diabetes is a chronic condition related to the endocrine system- the pancreas specifically. However, if complications get serious enough other parts of the body will be affected. In type 2 diabetes, the body's cells have become resistant to insulin, which is a hormone produced by the pancreas that allows cells to use glucose from the blood- your body's energy it needs to function. When someone is 'type 2', the food that person is eating is not able to fuel them, regardless of caloric content. Glucose is commonly called "blood sugar". It's a type of sugar that is processed and then transported via the circulatory system to your cells where it's needed. With type 1 diabetes (which used to be called "juvenile diabetes"), the pancreas does not produce any/enough insulin for some reason or another, generally because of autoimmune or other damage. [For me personally, I was diagnosed as an adult and had to have it confirmed as type 1 due to the presence of autoimmune antibodies, also apparently my pancreas hadn't quite given up at that point.] As we've seen before, insulin allows your body to use the food you are putting into it. As a double whammy, you can have type 1 with resistance, so not only is your body not producing any/enough insulin, what's there can't be used properly. [RIP Spider who has this] So to explain the effects, think about what happens when you're literally starving. Now imagine that's happening no matter how much you eat. Your body may go into starvation mode and store fat. This can be misleading, which when combined with fatphobia has people concluding that "well, you have diabetes because you're fat, duh". Heck, I have/had diabetic relatives who believed that eating too many carbs will automatically cause the condition because that's what everyone is told/assumes. Eventually, you'd starve and your body would start deteriorating as so. HOWEVER because you would have so much glucose that just sits there because it can't be used, your kidneys are going to work overtime to try and correct this- and they can't do it alone. Your liver can also suffer severe damage. That's not to mention a whole host of other complications that can occur.

So what about it? Well, obviously there are treatments. Insulin injections have existed since the 1920s. There are also medications that can help your body actually use the insulin it's being provided, be it naturally or artificially. So yes, people with diabetes are dependent on prescriptions to survive. My grandma lost a sister in childhood due to insulin treatments apparently not being available in the extremely rural area they were living in at the time. More recently, the israeli occupation has banned insulin from being distributed to Palestinians. [Insulin has also been used historically in psychiatric hospitals to force low blood sugar in psychiatric patients, but that's a whole other rabbithole about psychiatric abuse.] There are resources for the US and beyond if you or someone you know and/or love are in dire straits financially and need help with insulin or other diabetes medications/ related medical help. That's only one aspect of treatment, though. Because pain, stress, hormone changes, other medical issues, and plenty of other factors can raise your blood sugar to dangerous levels, other kinds of treatment to manage other factors may be necessary.

Now that that's out of the way, let's get to specifics. So the most common problem you're going to see mentioned is high blood sugar. We've already covered what the effects are, but what is considered high? For the most part, "high" is 200 milligrams per deciliter. My CGM (continuous glucose monitor) lists "high" as anything 181 or higher but stops giving an exact number after 350. This is why I had a good laugh that time I saw a scammer using an image of a meter reading glucose in the 120s- that's good blood sugar. If you're going to get even more specific you want your pre-breakfast blood sugar to be 80-130. So when you see an accompanying image reading in the 500s, that's extremely dangerous. That's "you're in danger of going into a coma" dangerous.

Insulin pricing? How come I'm seeing people saying they need $300? In the US, pricing cap was set to $35 somewhat recently. What this means is that per insulin pen (as far as I've experienced, the above-linked resource post should have links with better clarification) it's $35. Can't be more than that for one pen. How many doses that provides is very up in the air. It absolutely varies from person to person. I have relatives with type 2 that have to inject a dose of very long-acting insulin weekly, one has gone back and forth with daily doses on top of that. I'm type 1 and have to take one dose of long-acting nightly with injections of a short-acting insulin before every meal, with the exact dosage amounts varying per meal. Insulin is measured in units (there's probably an actual mL amount, both of mine are 100 units per mL with a 3mL pen). How many units someone needs is determined with their medical provider (or care team? When I went to 'diabetes education' after diagnosis I was set up with a "care team").

But at any rate, if someone is in an emergency situation in the US should be able to get an insulin pen for $35 pretty much when they get to a pharmacy. Yes, I get that this can be difficult in some situations, but that's outside the concept of insulin prices.

If someone's blood sugar is over 500 though, they almost certainly need a hospital more than they need an insulin pen. Yes, alright, the actual real single mother on twitter who was the source of the profile images/meter images that whatever the current url for vero-og has stolen and been using for months... that was actually months ago and I'm sure she doesn't need to be told to go to the hospital right now. [That said, if you get an ask from someone and the url is a variation off of 'vero-og' that is a confirmed scammer.] And then on top of that, yes, why would you block people that can get you free or discounted insulin? If someone was offering to save your life for free or find you what you need for far less than what you were expecting to spend, why wouldn't you take it? Unless what you're actually after is money.

SO TO RECAP: Insulin does not cost $300, $350, $370, whatever someone is sending you an ask about. In the US, it is federally capped at $35 per pen, with further resources available, as well as further resources being available internationally. If you need help, please be honest about it. I promise there are people who care, you don't have to try and explain yourself- but it absolutely does not cost that much and if it did, there are ways to lower the cost by quite a bit if there aren't resources to make it free. Diabetes is a lifelong chronic condition that is not caused by "being fat" or "eating too much", it is caused by your body not functioning right and your body can starve no matter how much food you eat. Unfortunately, people have been lying on this site for months if not years claiming to have type 1 with an insulin emergency. These people cannot possibly have diabetes, or they would be well aware that they do not need hundreds of dollars to get their insulin. They are counting on you not knowing this so you will donate to them. The 'vero-og' scammer had been harassing someone who donated and threatening them with the intention of bullying more money out of the donor.

#refdesk

381 notes · View notes

mindblowingscience · 9 months

Text

Diabetes is a condition in which the body produces too little or no insulin. Diabetics thus depend on an external supply of this hormone via injection or pump. Researchers led by Martin Fussenegger from the biosystems science and engineering department at ETH Zurich in Basel, Switzerland want to make the lives of people with diabetes easier and are looking for solutions to produce and administer insulin directly in the body. One such solution the scientists are pursuing is enclosing insulin-producing designer cells in capsules that can be implanted in the body. To be able to control from the outside when and how much insulin the cells release into the blood, researchers have studied and applied different triggers in recent years: light, temperature, and electric fields. Fussenegger and his colleagues have now developed another, novel stimulation method: they use music to trigger the cells to release insulin within minutes. This works especially well with “We Will Rock You,” a global hit by British rock band, Queen. To make the insulin-producing cells receptive to sound waves, the researchers used a protein from the bacterium E. coli. Such proteins respond to mechanical stimuli and are common in animals and bacteria. The protein is located in the membrane of the bacterium and regulates the influx of calcium ions into the cell interior. The researchers have incorporated the blueprint of this bacterial ion channel into human insulin-producing cells. This lets these cells create the ion channel themselves and embed it in their membrane.

#science #stem #medicine #diabetes #biotechnology #insulin

487 notes · View notes

wellextol · 3 months

Text

youtube

Glucodyn Supplement Review - The Best Vitamins for Managing Type 2 Diabetes and Insulin Resistance

0 notes

scientia-rex · 11 months

Text

Hysteria isn't a fucking thing

ok fun fact: I'm rapidly becoming a cult favorite doctor among our local privileged elderly white ladies, which I have mixed feelings about, but the #1 reason is that I just don't leap to "anxiety" as an explanation for symptoms unless the patient tells me "I am anxious, and then I feel these symptoms, and when I am not anxious, I don't feel these symptoms."

The sheer number of women I've seen who've been told for years to decades that the only thing wrong with them is anxiety is fucking staggering, in this Year Of Our Lord 2023, and I just keep digging. We checked a basic lab panel, sure. CBC. No anemia. CMP. Kidneys are fine. (Electrolytes are basically always going to be fine if someone is well enough to walk into my office under their own power to talk to me. Exception is mild chronic hyponatremia.) And we check thyroid. TSH and free T4. We check blood sugar. A1c, if the fasting is a little weird. Fasting insulin, if I'm still suspicious. We check cortisol. Inflammatory markers--ESR and CRP.

And eventually, if the symptoms support it, or right away, depending on my level of suspicion, we check rheumatological labs for abnormal autoimmune function. Anti-nuclear antibody. Rheumatoid factor. There's at least a dozen you can check, and which ones you should check is always a matter of debate and also of expertise that I 100% lack. We are out in the sticks. There are no "local" rheumatologists for me to send people to.

But a couple of weeks ago I found a woman--she has bipolar disorder and has been told for decades that's all that's wrong with her--who has an anti-centromere antibody titer that's fucking through the roof. I found an anxious 19-year-old with an ANA of 1:1380. And yesterday I found out why a sweet elderly woman I've seen for a year or two now started feeling crappy months ago: her rheumatoid factor is over 90.

Rheumatological disorders are always difficult. Our understanding of them varies from "pretty good, actually, and here are useful treatments" to "Well I Guess That Exists." Labs aren't always a slam-dunk and even labs plus symptoms can give you misleading impressions. Your immune system can decide that virtually any short chunk of protein is an enemy, and the problem with that is that your body is made up of many, many, many short chunks of proteins, so the odds that you'll develop some kind of antibody against yourself just keeps going up over your lifetime. Immune disorders tend to travel in packs; there's a clear genetic element to it, so the more first-degree relatives (parent, sibling, child) you have with any kind of autoimmune disorder (including Type 1 diabetes), the higher your risk of any kind of autoimmune disorder is, and if you already have one autoimmune disorder, you're at higher risk for developing another one.

But I think it's precisely because they're difficult that a lot of mainstream primary care prefers to pretend they don't exist, rather than try to sift through the utter fucking mess that is Mixed Connective Tissue Disorders, a title that has fallen out of favor since I learned it in my third year of med school. And women are at higher risk for autoimmune disorders than men. And older women are at higher risk than younger women.

So if I, as a family doc, just keep digging, just keep poking at the tangled knot of symptoms, there's a decent chance I will uncover something interesting. Hopefully something treatable. Sometimes we have nothing to treat with, and I just get to offer someone more understanding of their disorder, which feels pretty paltry but is better than the casual dismissal of "You're just anxious."

Never, ever, ever take anxiety as a diagnosis for a symptom other than anxiety. Not even as a rule-out. Keep those symptoms as an open question mark on the patient. Don't say "anxiety" just so you can close the door. And damn sure don't do it to women.

I'm actively working on learning more so I can be more helpful, in our Rheum-less community, so if you have good lectures or books, please drop me a lead.

#the attending dr. kristophine

635 notes · View notes

needlepokes · 1 month

Text

how to write a diabetic character: CGM edition

is your diabetic character wearing a CGM? do they have to? CGMs these are Continous Glucose Monitors that can detect how much sugar is in your bloodstream.

How are they different than tradtional fingerprick (blood) tests? they take blood sugar readings 24/7, and provide you with how your sugars are doing at all times, rather than just at that moment. This leads to tremendously better control over blood sugar.

The way they work is that they can "sample" your blood sugar by testing your subcutaneous tissue for sugar levels then adjusting that value.

However, they're less accurate than a fingerprick (blood) reading and will often "lag" behind by about 15 minutes.

SO if you have a character who is expereincing low or high blood sugar - they'd get an alarm on their CGM, and then they might take a fingerprick reading to make sure. CGM false alarms DO exist and it can cause some very annoying situations.

A less careful/depressed/struggling/burnt out character might A. not care or "sleep through" alarms B. not double check with a finger prick C. not care that they're wearing a CGM - pump into stuff or just rip it off (although they are very expensive!).

can you mute them? yes, and a character might choose to do this while they're sleeping, having an exam, or if they know they're about to fuck up their blood sugar.

how long do they last? the libre ones last 14 days. the dexcom ones last up to 10 days.

can you shower with them? yes

can you swim with them? yes

can you have sex with them on? yes, and i've read very funny anecdotes from diabetics having to pause during sex because their cgm was beeping

are they expensive? yes! sometimes, they're covered by insurance, but not completely. If a character is in poverty, or do not have insurance, they likely would have to rely solely on fingerpricks.

Who usually uses CGMs? they are very widespread between T1Ds and are increasingly being used by T2Ds as well.

can you share the readings on multiple devices? yes! your character might share their info with their SO, parents, roommates, close friends...etc. It is genuienly one of the most telling signs of a close relationship between people - because those people will see your "mistakes" and decisions.

where do you stick them? the libre ones (circular ones) officially just go on the back of your arm. The dexcom ones can go on just about anywhere that's "soft" - stomach, thighs, back of arm, chest...etc.

does putting them on hurt? sometimes! the way they are installed involves a needle going into the skin then sitting in the subcutaneous tissue. This can sometimes cause some bleeding, and soreness for a few hours.

Often times the process is completely painless, but this is not the case for everyone. A thinner character might struggle to find a place "cushy" enough for a cgm.

can you put them on your own? yes the process is made for one person to stick it on, but i've seen some couples on instagram act all romantic and sappy about applying it together, so that should give you some ideas for your diabetic characters' budding romances ;)

Some CGMs are just naturally faulty, i'd say about 4 sensors is a busted one, and in that case you'll have to replace them - which most companies just do without any hassle.

do they work with insulin pumps? some insulin pumps can work in tangent with CGMs and provide feedback for the user to automatically generate the correct doses of insulin, depending on their current blood sugar.

do they come off easily? depends on who you're asking. some people swear up and down that they never last and have to put on patches, which are admittedly very cute. Weather, clothing, and how clumsy a character is all factor in this. For me personally i just put them on raw and keep them together by sheer willpower.

CGMs can cause anxiety in diabetics. The constant flow of information can easily burnout people, and this can possibly be the case for any diabetic character you might write. Seeing arrows going down or up can be very distressing, especially knowing how painful some of the consequences are. I personally take breaks for both myself and my wallet from using CGMs to avoid burn out.

nonetheless, CGMs are WONDERFUL pieces of technology that have personally made me much happier as a diabetic, freer and a lot more independent.

does your character want their CGM to show? lots of people, including myself don't like revealing their CGMs - but your character might like showing them off!

and lastly - my favorite thing about CGMs - taking them off and having a "naked" shower once a month where i dont have to worry about it coming off. - They look like this:

#actually diabetic #diabetes #writing tips #diabetic #CGMs #dexcom #freestyle libre #T1D #T2D

58 notes · View notes

alicerosejensen · 11 months

Text

Just headcanons with Leon and his daughter who has a chronic illness

Leon x daughter!sick (diabetes, epilepsy or any other severe chronic disease)

√ Hey, Leon carefully guards his child! however, there are not always things from which he can protect his daughter.

√ I see Leon as a very caring father. He will worry if his daughter's knee is torn from a fall from a bicycle and carefully treat her wound and bind it up if necessary. He will also monitor how her childhood injuries are healing.

√ Having seen so many horrors in the world, Leon takes even a simple cold seriously. If the temperature does not decrease even after taking an antipyretic, Leon will prefer to take his daughter to the hospital.

√ Leon hardly knows the symptoms of the diseases, but he noticed an unusual dryness of the skin and the smell of acetone in combination with other symptoms. If his daughter loses consciousness in front of him, it will drive him crazy. All the way to the hospital, Leon will hold her in his arms and kiss her on the forehead or the top of her head.

√ Nevertheless, he will not allow himself to show fear of his daughter. No matter at what age she is diagnosed with it, Leon will be her strongest support. He will learn everything about this disease and his concern will only increase.

√ He is paid very well for risks at work, so the question of money is never acute. Leon will make sure that his baby receives good treatment, which will be corrected by doctors in time and he will repeatedly take her to an endocrinologist and other necessary examinations.

√ Measure your blood sugar level every day and make sure that the insulin injection is done on time? Papa Leon is watching this very carefully. He even keeps a blood sugar control log.

√ Does she need a home education? Leon will study this issue, and if necessary, then no problem.

√ It is important to understand that under no circumstances will he leave his child alone with these diseases. He will never tell his wife/girlfriend to deal with this shit alone.

√ Will take her to all medical procedures.

√ He's such a loving dad. He always convinces his little girl that her illness does not make her inferior. Spends time with her looking for classes available to her.

√ He will definitely not allow his child to be offended.

√ He will turn on her cartoons and lie next to her in the nursery until she falls asleep. Actually, Leon, because of his daughter's illness, can check her well-being even at night.

√ He definitely knows how to provide first aid, but for the sake of his daughter, learn to put injections more carefully so as not to leave bruises and not cause her great pain.

√ Always consults with specialists on any medical issues.

√ Leon will always take care of his child's well-being. This is what he highlights, if nerves or stress affect her health, then he will comfort her and say that no excitement is worth her well-being. For Leon, the daughter is a little diamond, no matter what she is ill with.

√ If a chronic illness is caused by a severe injury (for example, a traumatic brain injury), Leon will literally hate himself for not looking after his child well.

√Again, medications are very expensive, as well as treatment, but Leon is ready to do everything possible so that his child does not need anything. If she gets epilepsy later, Leon will try to always be there to help his baby.

√ Leon will always try to be there. When she is in the hospital, he will provide her with the full care that is possible.

√ It does not matter what kind of disease she has, he will still study the Internet and books studying this diagnosis in order to know better how to help his child.

√ Perhaps his daughter will be banned from playing sports or attending summer camps, depending on how serious everything is, then Leon will try to find a good alternative with her.

√ All medicines will always be at hand.

#leon kennedy #leon scott kennedy #leon s kennedy #resident evil #leon scott kennedy x daughter #dad leon s kennedy #dad leon kennedy #older leon kennedy #leon kennedy resident evil #papa leon #leon #leon kennedy headcanons #resident evil headcanons #headcanon #leon Kennedy dad #papa leon s kennedy #resident evil leon

180 notes · View notes