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#pregnancy complications
reasonsforhope · 7 months
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Researchers from Western and Brown University have made groundbreaking progress towards identifying the root cause and potential therapy for preeclampsia.
The pregnancy complication affects up to eight per cent of pregnancies globally and is the leading cause of maternal and fetal mortality due to premature delivery, complications with the placenta and lack of oxygen.
The research, led by Drs. Kun Ping Lu and Xiao Zhen Zhou at Western, and Drs. Surendra Sharma and Sukanta Jash at Brown, has identified a toxic protein, cis P-tau, in the blood and placenta of preeclampsia patients.
According to the study published in Nature Communications, cis P-tau is a central circulating driver of preeclampsia – a “troublemaker” that plays a major role in causing the deadly complication...
“The root cause of preeclampsia has (so far) remained unknown, and without a known cause there has been no cure. Preterm delivery is the only life-saving measure,” said Lu, professor of biochemistry and oncology at  Schulich School of Medicine & Dentistry...
“Our study identifies cis P-tau as a crucial culprit and biomarker for preeclampsia. It can be used for early diagnosis of the complication and is a crucial therapeutic target,” said Sharma...
Until now, cis P-tau was mainly associated with neurological disorders like Alzheimer’s disease, traumatic brain injuries (TBI) and stroke. This association was discovered by Lu and Zhou in 2015 as a result of their decades of research on the role of tau protein in cancer and Alzheimer’s.
An antibody developed by Zhou in 2012 to target only the toxic protein while leaving its healthy counterpart unscathed is currently undergoing clinical trials in human patients suffering from TBI and Alzheimer’s Disease. The antibody has shown promising results in animal models and human cell cultures in treating the brain conditions.
The researchers were curious whether the same antibody could work as a potential treatment for preeclampsia. Upon testing the antibody in mouse models they found astonishing results.
“In this study, we found the cis P-tau antibody efficiently depleted the toxic protein in the blood and placenta, and corrected all features associated with preeclampsia in mice. Clinical features of preeclampsia, like elevated blood pressure, excessive protein in urine and fetal growth restriction, among others, were eliminated and pregnancy was normal,” said Sharma.
Sharma and his team at Brown have been working on developing an assay for early detection of preeclampsia and therapies to treat the condition. He believes the findings of this study have brought them closer to their goal...
“The results have far-reaching implications. This could revolutionize how we understand and treat a range of conditions, from pregnancy-related issues to brain disorders,” said Lu.
-via India Education Diary, September 22, 2023
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syoddeye · 3 days
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this idea is ruining my life please take it away from me: young john price who donated sperm a couple times when he was younger for cash and it ended up in the freezers for a while until years later when some young thing who was fully prepared to be a single mom used his sperm to get pregnant
except now she's having some complications in her 2nd trimester and the doctors legally have to contact price for his medical records and he finds out he's gonna be a dad
i am so flattered you came to my inbox with an idea - sincerely, i love it when it kind anons pop in to share worms - but unfortunately, i do not think i am the person to write this.
now, never say never, because who knows, maybe some day i'll go down an adjacent track such as the "a 141-er meets a single parent" express, but i don't see myself boarding anytime soon.
apologies anon. but i really really appreciate you thinking of me, it is very sweet.
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pro-birth · 1 year
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healthyboom · 10 months
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Pregnancy: What to Expect and How to Prepare
Embarking on the journey of pregnancy can be both exciting and overwhelming. This comprehensive guide offers valuable insights into what to expect during pregnancy and how to prepare for this transformative experience. From the early stages of conception to the final moments of labor and delivery, you'll find a wealth of information on prenatal care, nutrition, exercise, and maintaining a healthy lifestyle. We'll address common pregnancy symptoms, potential complications, and provide tips for managing discomfort. Additionally, we'll delve into the emotional aspects of pregnancy and offer guidance on creating a supportive environment. Get ready to navigate pregnancy with confidence and embrace the joy of welcoming your little one into the world.
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twitt3rpate · 10 months
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"NOTHING LASTS FOREVER."
Several months have passed from the infamous fight at the airport in Germany. Since then, newly married Steve and Natasha have been reunited. They spend their days running secret op missions and pass the remainder of the time in musty hotels with Sam, Wanda, and occasionally Vision.
That is until Natasha is separated. Alone and pregnant, the Black Widow must navigate Eastern Europe with nothing but a gun and her skills on the side. 
Or that is until she finds some old friends, family really. The past catches up with her and Natasha must choose who can she trust with her massive secret. 
She now lives among killers, assassins, and spies. Old friends and potential allies threaten to slit her throat if she dares to fall asleep. The Black Widow must learn to evolve.
One things for certain though, she will stop at nothing to protect herself and the impossible life now growing within her.
ORIGINALLY POSTED ON WATTPAD UNDER SAME USERNAME. COPYRIGHT.   @marvel       &         twitterpate
All chapters are available on ao3. Read now! 
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sir-crocodile-slut · 2 years
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Me genuinely curious but likely coming off as an asshole but I swear it’s cause I don’t understand about pregnancy/fetuses/emergencies/etc
I know it’s for tv/movie purposes (and I know it sometimes happens in real life)…
But I don’t understand that if there’s an issue that’s irreversible with the fetus (ectopic, organs not developing properly, etc)…. But people try to let it be and not terminate or if it’s viable, have surgery…. I do not understand the lack of reasoning and logic to put yourself in harms way for an impossible chance at a healthy baby
I’m watching Chicago MED and a woman was pregnant with twins, the boy was not developing organs properly and it would not get better, and the girl had it’s growth halted due to fluid caused by the boy’s growth. Docs said it was best to terminate the boy, as the girl had the best chance and the boy would never be able to recover or have a quality of life… and the woman was like “oh no I can’t lose the boy I can’t have the surgery!! Ill take this chance at them healing on their own!!”
I legitimately don’t understand why people make these decisions in both tv and reality… like yes it is disappointing but… that’s the worst of it compared to having two babies that will not be able to survive.
I understand how this can sound I know I sound like a total asshole but I don’t get it because the logic and reasoning and science and statistics behind it doesn’t make sense….
Like I’m sorry you’re disappointed that this pregnancy didn’t work out but… it’s not that bad?? It’s not worth having stillborn babies or babies born in horrific pain as well as the multiple health risks and death risk to the mom?? Am I insane??
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gwydionmisha · 1 year
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dratefahmed1 · 7 hours
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Pregnant Women Trauma A Comprehensive Guide for Medical Professionals #pregnantwomenstrauma #medicin
#pregnantwomenandtrauma #traumaandpregnancy #maternalmentalhealth #perinatalmentalhealth #postpartumdepression #postpartumanxiety #perinataltrauma #birthtrauma #healingfromtrauma Truama Surgery By Dr atef Get your Copy Now Other Books Of The Author #traumasurgery #artificialintelligence #ai #traumasurgery #medicalstudents #medicaldoctors #surgery…
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youcantjustjudgeme · 10 months
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Like and Reblog to see my special Pregnancy nude pictures and videos In your dm
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What Happens if Your B12 Deficiency Is Left Untreated?
What Happens if Your B12 Deficiency Is Left Untreated?
Introduction: Vitamin B12, an essential nutrient for nerve function, red blood cell production, and DNA synthesis, plays a critical role in maintaining overall health. However, when B12 deficiency goes untreated, it can lead to a range of health issues, from minor discomforts to severe complications. In this blog, we’ll explore the potential consequences of ignoring B12 deficiency and why timely…
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zwriteseverything · 5 months
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Something crazy to think about my pregnancy and how miserable I was cause of all the issues but not one person let me feel that pain the amount of people that showed up and showed out and just made sure to make me pregnancy an amazing experience I think about y’all often. 😍
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amethystamanda · 8 months
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999 BCE
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The year starts cold and Kealoha-filled.
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They come and go, but they never seem to leave.
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Something is making Hunith very sad. The baby? The Kealohas? Memories of lost tribe members? Maybe all of those. She'll get through it, but it's tough.
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Late in her pregnancy, Hunith starts to feel cramps. Is something wrong with the baby? Are they coming now? She and Lilliana go visit the local healer. She's glad there's another woman around.
She's terrifed, but everything turns out okay.
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Late in the year, Hunith had a baby boy, who she called Gryffyd.
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And the Kealohas may be gone? Finally? Time will tell.
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jammiscanstamil · 1 year
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