#VirusVaccines

[whcekg]

Products are getting better and better. How do you think?

#CEKG #Bioreactor #bioprocessing #upstream #VirusVaccines #AdenovirusVector #Protein-based #Vaccines #VLP #biotechnology #biotechindustry #biodefence #biofuels #biological #biopharmaceuticals

[bishicat]

"V placed her chin on the side of the tub, looking over at him. He could’ve leaned forward and kissed her if he wanted."

...so I wanted to illustrate the chapter 2 bathtub scene from silkspecter's fanfic, just like honey (the first fanfic that got me feral for this ship). And since the author left V's appearance pretty ambiguous, I drew my V instead :)

Edit: the author is the wonderful @t-virusvaccine 💖

#“just like honey” was THE fanfic that made me a silverV shipper #it's just so good 😭 #the characterization was amazing and the smut was impeccable #sidenote: i dont like this piece too much from an artistic pov haha i couldnt get their skin right and i need more background practice fr #anyways i wanted this to feel like a hazy romantic snapshot of a memory #cyberpunk 2077 #cyberpunk 2077 fanart #cp2077 #cp77 #fem v #cyberpunk 2077 v #silverV #johnny silverhand #just like honey #my art #digital art #bishiart #oc: vivienne

[dejufuniverse]

Quebec is begonnen met het inenten van mensen met het pokkenvaccin.

Als ze beginnen met het inenten van mensen met het pokkenvaccin, zullen een heleboel mensen pokken krijgen.

Volgens CDC brengt het pokkenvaccin een groot risico van besmetting met zich mee, omdat het een levend virusvaccin is dat zich verspreidt.

https://www.cbc.ca/news/canada/montreal/monkeypox-vaccine-quebec-1.6466449

[newscheckz]

Kim Jong Un vaccinated, is it safe?

New Post has been published on https://newscheckz.com/kim-jong-un-vaccinated-is-it-safe/

Kim Jong Un vaccinated, is it safe?

An outbreak of corona virus cannot be ruled out in North Korea as the country had not restricted movement and business transactions with China before the border restrictions were out in January 2020.

This is according to South Korea`s National Intelligence Service, this comes even as it was disclosed by Microsoft a month ago that two North Korean hacking groups had tried to break into vaccine developers network in multiple countries, with no specific company targeted.

Sources indicate that North Korean leader Kim Jong Un has been provided an experimental corona virus vaccine by China together with his family, confirming this Harry Kazianis an expert from North Korea at the centre of National Interest think tank in Washington has said that Kim and several senior North Korea officials had been vaccinated.

It is not clear if the drug is safe and which company had supplied it. At least three companies from China are on the race developing a corona virus vaccine according to medical scientist Peter Hotez.

#covid-19vaccines #northkorean #virusvaccine #Opinion

[faceofmalawi]

US to buy 100 million doses of potential virus vaccine

The US government has agreed to pay almost $2 billion for 100 million doses of a potential coronavirus vaccine, German firm BioNTech said on Wednesday. BioNTech, which is developing the drug with US pharma giant Pfizer, said in a statement that American people would receive the future vaccine “for free” in line with the Trump administration’s “commitment for free access for COVID-19 vaccines”. Under the agreement, the US government has placed an initial order for 100 million doses to be delivered if regulatory approval is granted. The US government also has an option to purchase as many as 500 million additional doses, BioNTech added. Labs around the world are racing to produce a vaccine to help end the worst health crisis in over a century. More than 200 candidate vaccines are currently being developed with roughly two dozen at the stage of clinical trials with human volunteers. BioNTech and Pfizer have narrowed their vaccine candidates down to two frontrunners and waiting for the green light to begin a mass trial involving 30,000 healthy volunteers, which may happen later this month. Subject to successful outcomes and regulatory approvals, Pfizer and BioNTech expect to manufacture up to 100 million doses by the end of 2020, and “potentially more than 1.3 billion doses by the end of 2021”. Their vaccine method relies on using messenger RNA, genetic code that slips into human cells to make them generate antibodies that are specifically tailored to the coronavirus. Trials so far have shown that their treatment triggers “robust” antibody and T cell immune responses against the novel coronavirus, according to BioNTech. The agreement between the US, Pfizer and BioNTech “increases the odds that we will have a safe, effective vaccine as soon as the end of this year”, said US health official Alex Azar. A BioNTech spokeswoman told AFP that two injections would probably be needed for maximum protection, with the booster shot following seven days after the first injection. Based on the price paid by the US government, it would, therefore, cost $39 to immunise a person against the deadly virus. Oxford University and AstraZeneca are also working on a vaccine, which they have vowed to make available “at cost price”, amounting to roughly $2.90 per unit. afriupdate Read the full article

#afriupdate #virusvaccine

[meilanhsiao]

Good news. The first #vaccine for #COVIDー19 developed bY science teams in #WuHan has successfully completed the Q&A and received approval for office #clinicaltrials. Look forwards more good news based on solid scitific #data_facts from #China .This is the example of #bestpractice for #virusvaccine research and development. #偉哉中國 (at Belgium Chinese Tea Arts Centre) https://www.instagram.com/p/B_waUmqncq_/?igshid=1knq18ln66y96

#vaccine #covidー19 #wuhan #clinicaltrials #data_facts #china #bestpractice #virusvaccine #偉哉中國

[tipsmaatregelen]

Nederlanders vernietigen 800.000 ongebruikte coronavirusvaccins

Nederlanders vernietigen 800.000 ongebruikte coronavirusvaccins Ruim 800.000 door de Nederlandse overheid bestelde corona-virusvaccins worden vernietigd omdat ze niet nodig zijn, minister Kuipers van Volksgezondheid heeft parlementsleden verteld. ‘Veel landen hebben aangegeven genoeg vaccins te hebben om in de nabije toekomst aan de nationale vraag te voldoen’, zegt Kuipers. COVAX, het…

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[juniperpublishers-jdvs]

A Broadly Protecting Influenza Vaccine Relies on New Adjuvans Effects-Juniper Publishers

JUNIPER PUBLISHERS-OPEN ACCESS JOURNAL OF DAIRY & VETERINARY SCIENCES

Short Communication

Vaccines used against seasonal influenza are poorly effective against influenza A viruses of novel subtypes that may cause pandemic. Pre-pandemic influenza vaccines are poorly immunogenic against the upcoming pandemic virus that might be overcome by the use of a potent adjuvant. In humans, a limited number of adjuvants has been approved for human use and mostly human influenza vaccines are not adjuvanted.Furthermore, pre-pandemic influenza vaccines are poorly immunogenic to the upcoming pandemic. Thus, there is a need for alternative safe and effective adjuvants that can enhance the immunogenicity of influenza vaccines and that promote the induction of broad-protective T cell responses. Most studies of pandemic outbreaks have been done in humans. Also in animal spp problems exist with influenza virus infections. However, in the animal field the situation is different where one and the same influenza virus strain may circulate in the population finding new accessible victims in new non-exposed individuals.

Influenza virus infections cause severe morbidity and mortality in the human population [1]. For overcoming such problems annual vaccination of high risk groups is recommended. The inactivated trivalent influenza vaccines are used that elicit strain-specific antibodies [2,3]. However, these vaccines fail to afford long lasting protection due to antigenic drift of influenza viruses [4-6] but also human Influenza vaccines are not highly immunogenic requiring regular updating.

Vaccine strains not matching the infecting virus have reduced effectiveness [7]. The emergence of an antigenically distinct influenza virus of a novel subtype triggers a pandemic to which inactivated seasonal influenza vaccines afford little protection [4]. Thus, it is obvious that influenza virusvaccine should be formulated that not only induce neutralizing antibodies to seasonal influenza viruses but also induce more broadly protective immune responses over alternative protective antigenic determinants also on alternative proteins and recruiting alternative immune mechanisms.

In a recent study at Carolien E,et al. [6], Dept of viroscience, Erasmus university MC,) Rotterdam, The Netherlands evaluated a novel nanoparticle, G3, as an adjuvant in a seasonal trivalent inactivated influenza vaccine in a mouse model. The G3 adjuvant was formulated with (G3/DT: DT, for diterpenoid). or without steviol glycoside diterpenoid. The use of both formulations enhanced potently the virus-specific antibody responses to all three vaccine strains. The adjuvants were well tolerated without any signs of discomfort. To assess the protective potential of the vaccine-induced immune responses, an antigenically distinct H1N1 influenza virus strain, A/Puerto Rico/8/34 (A/PR/8/34), was used for challenge infection. This strain was selected because it like the H1N1 virus in the most recent influenza virus outbreak lacked hemagglutination (HI) and virus neutralizing (VN) epitopes on the HA-protein.The vaccine-induced antibodies did not recognize HI or VN antigenic determinants on the challenge virus i.e. it did not cross-react with strain A/PR/8/34 in HI and VN assays. However, mice immunized with the G3/DT-adjuvanted vaccine showed Protective immunity against A/PR/8/34 infection, which correlated with the induction of anamnestic virus-specific CD8+ T cell responses to epiotopes located on the structural nukleo protein (NP) and more remarkable on the non-structural polymerase A (PA), which were not observed with the use of G3 without DT.

G3 and G3/DT enhance the vaccine-induced antibody responses upon vaccination none of the mice displayed any signs of discomfort. Limited weight loss (<2%) was observed during two days post vaccination in some mice randomly distributed over the experimental groups, including those that received PBS only All mice that received the trivalent inactivated influenza vaccine i.e. non-adjuvanted vaccine or vaccine adjuvanted with G3 alternatively with G3/DT developed HI antibody titres against the three vaccine strains (A/California/7/2009, A/ Victoria/361/2011 and B/Hubei-Wujiang/158/2009) after the first vaccination. The geometric mean titers (GMTs) of mice that received the vaccine with adjuvant G3/DT or G3 were significantly higher than those of mice that received the nonadjuvanted vaccine.Four weeks after the second vaccination the GMTs against the vaccine strains increased in the mice receiving the non-adjuvanted vaccine. Although the GMTs of groups that received the G3/DT and the G3 adjuvanted vaccine respectively, did not increase after the second vaccination, they remained significantly higher than the GMTs of receiving non-adjuvanted vaccine adjuvant) (p<0.01).

In none of the mice, vaccine-induced antibodies were cross-reactive with the influenza virus challenge strain A/ PR/8/34. Virus-specific CD8+ T cells were detected in the G3/ DT adjuvanted vaccine group only. The CD8+ T cells were specific for the NP366-374 and the PA224-233 epitopes present in the A/ PR/8/34 influenza A vaccine strains and the A/PR/8/34 virus used for challenge infection. Thus, CD8+ T cells had contributed to the protection observed in mice that received the G3/DTadjuvanted vaccine. Weight loss is a disease criterion and all mice vaccinated or not displayed similar weight loss, starting at day 2 p.i. until day 4 p.i. From day 5 p.i. onwards mice vaccinated with the G3/DT-adjuvanted vaccine started to gain weight and recovery. Furthermore, The G3/DT adjuvanted vaccine restricted virus replication in the lungs compared to the other two vacc8ine groups van De Sandt[7]

Conclusion

G3/DT improves the protective efficacy of the split virion vaccine against an antigenically distinct influenza virus challenged two weeks after the second vaccination mice with a lethal dose of influenza A/PR/8/34.

Regardless the influenza virus infects man or animal there is a need for update of Influenza virus vaccines. Here we give clear evidence that influenza virus vaccine can be formulated to inducing broadened immune protection. Most important now is to define & design efficient adjuvants recruiting new antigen and antigen determinants and alternative immune mechanisms. Here, I like to underline an innovative mechanism of the G3/DT adjuvant that can enhance the immune mechanism harboured in RNA by promoting expression of the non-structural PA containing an immune protective epitope. That and other effects named in this article should stimulate adjuvant development and open for enhancing protection mechanisms overcoming the evasion mechanisms of influenza virus as well of other pathogens.

For more Open Access Journals in Juniper Publishers please click on: https://juniperpublishers.com/open-access.php

For more articles in 

Open Access Journal of Dairy & Veterinary sciences

 please click on:

https://juniperpublishers.com/jdvs/index.php

#Pre-pandemic #Virus neutralizing #Journal of Dairy #Juniper Publishers #open access journals

[jucelinoluzposts]

Valse virusvaccins zijn te vinden in China en Zuid-Afrika in 2020 en 2021

Valse virusvaccins zijn te vinden in China en Zuid-Afrika in 2020 en 2021

Valse virusvaccins zijn te vinden in China en Zuid-Afrika in 2020 en 2021 “Stel je voor, als vaccins tegen echte virussen al eng zijn, stel je dan de valse voor die in 2020 en 2021 in China en Zuid-Afrika zullen worden aangetroffen” Águas de Lindóia, 3 december 2020 Inhoud ontleend aan brieven van Jucelino Luz – voortekenen Interpol zal vaccins vinden in China en Zuid-Afrika die duizenden…

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[wanderingaldecaldo]

I don't believe in the existence of angels But looking at you I wonder if that's true

gorgeous commission by @t-virusvaccine

#mitch anderson #valerie vermilion #i'm so in love with this #the shading #her freckles #her shirt #his face 😭 #it's so gorgeous #my commissions #cyberpunk 2077 #cyberpunk fanart #cyberpunk 2077 fanart #t-virusvaccine #lyrics: nick cave #fem v #female v #cyberpunk female v #mitch x val

[buddylistsocial]

NTD News Today Full Broadcast (Sept. 24)

NTD News Today Full Broadcast (Sept. 24)

Two officers are recovering after being shot in Louisville, Kentucky on the heels of the Breonna Taylor court decision, President Donald Trump announced $200 million of CARES Act funding to support states when a CCP virusvaccine is approved, and a joint congressional report outlines potential conflicts of interest between the Bidens and Ukraine, and zeros in on what some consider Hunter Biden’s…

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#Archived #CARES Act #CCP Virus #Live Videos #News #News Videos #NTD News Today #Video

[tsvete]

Put your music on shuffle and add the first 10 songs you get 

1. FM-84 - Never Stop (feat. Ollie Wride)

2. Papa Roach - Sunrise Trailer Park ft. Machine Gun Kelly

3. Major Lazer - Powerful (feat. Ellie Goulding & Tarrus Riley)

4. THEN JERICO - Big Area

5. Henry Jackman & Matthew Margeson - Manners Maketh Man

6. Plan B - Heartbeat

7. Hozier - Someone New

8. The Script - The Man Who Can't Be Moved

9. Suede - Like Kids

10. Scouting For Girls - Love How it Hurts

I’m tagging @arewetumbling, @fyeahhartwin, @jenniferjuni-per, @i-am-avacado, @heyitsthatgirl, @t-virusvaccine

[tincansamurai]

tagged by @downwithpeople

a. - age: 23 b. - biggest fear: bein dead and not existin anymore c. - current time: 11:44 AM d. - drink you last had: drinkin some green tea as i type the e. - everyday starts with: not wanting the day to start, thinking about my dreams g. - ghosts, are they real: i am skeptical but i also lived in a house i am 100% sure was haunted so probably ghosts are real h. - hometown: i don’t have a town i really want to call my hometown i. - in love with: tall elves j. - jealous of: tall elves k. - killed someone: why would anyone admit this in a tag game, this some secret fbi shit l. - last time you cried: uhh jeez probably like two weeks ago for no discernible reason m. - middle name: louise o. - one wish: motivation to get better at art p. - person i last called/texted: last week i was in a group text with my coworkers q. - question you’re always asked: “why don’t you sell your art?” and then i cry r. - reason to smile: lots of lovely people on this internet s. - song last sang: a remix of the mob psycho end theme that came up while i was looking for new music t. - time you woke up: like 10:30 am, i ignored my alarm u. - underwear: i am wearing a pair of shorts as underwear even though i just did laundry v. - vacation destination: literally anywhere not in the tristate area w. - worst habit: i pick my nose like all the time and i can’t stop y. - your favorite food: burritos z. - zodiac: cancer/cock. big dick crab man

tagging these ppl: @durnehviir, @t-virusvaccine, @abadbadman, @captain-doyal, @kolali

if i ain’t tag ya and you wanna do it you can say i tagged u

[leonmelinda-blog]

According to the Environmental Protection Agency

The Dons lost three key guards from last year's 25 5 team that fell in the NorCal semifinals to eventual state champion St. Mary's of Stockton. They return two key front liners in King Bischof (17.0 ppg), a relentless 5 10 senior forward, and 6 1 post, who is an excellent athlete with 3 point range.

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