#The fact I get questioned on the phytoestrogen thing is a good sign for the site culture btw because | Explore Tumblr Posts and Blogs

bonefall · 6 months

Note

Question: what’s your source on the phytoestrogens? Bc the only times I’ve ever heard that claim, they all source back to this one study on sheep in like the 40s, which… well it’s not very well supported

(Although maybe you don’t care about that, which would be fair. These are fictional cats after all not clinical studies)

You're probably coming from Hbomberguy when he was specifically addressing lunkhead chuds, who pass around the claim that phytoestrogens lower human fertility and sex drive. The "soyboy" claim.

Human studies on the effects of phytoestrogens are pretty lacking overall, but what does exist doesn't back up that claim-- because humans don't graze on red clover in west australia like a sheep. What that means is that it doesn't impact human fertility the way a terrified conservative brain stem thinks it does.

(ESPECIALLY not in a plate of soybeans, which has significantly lower levels of phytoestrogen than red clover.)

But what it DOES do is bind to the estrogen receptors in your body (and acts as a really good antioxidant but that's neither here nor there) which can mean it can act AS estrogen... or as an antagonist.

If you want to know more (especially if you have a background in chemistry, this source talks a lot about the structural similarities between estrogen and phytoestrogen and the mechanism of action) then go dive into PHYTOESTROGENS IN FUNCTIONAL FOOD by Fatih Yildiz, which collects together many of the studies that we do have on the matter and omits controversial ones.

(Plus it's an easy read for such a science-heavy publication imo)

Though I have to stress that my HRT guide is, y'know, fake cats! Nothing in nature replaces modern medicine***, but I wanted to make a good resource for WC fans with trans cats who wanted a little bit of scientific accuracy, wanted to cut herbs that cast Liver Failure 1000 on felines, and could reasonably be found in a temperate environment

***= Except medicinal maggots. Medicinal maggots are literally magical. Nothing debrides necrotic tissue like green bottlefly larvae and as far as I'm concerned they're the closest thing to divinity we have on this earth. And medicinal leeches I love you leeches im so sorry that anyone has ever called you a pest you're cherubic angels and she doesnt deserve this </3

#Herb guide #Bone babble #Phytoestrogens #Btw I have wanted to remake that guide for a while since it actually predates most of my other work #That was like... the first research project I did for this blog #And in the next draft I'm cutting comfrey root entirely because I got more comfortable with speaking over the erins #The fact I get questioned on the phytoestrogen thing is a good sign for the site culture btw because #It shows that people are both a little educated on a conservative pseudoscience claim #And that they're questioning the information even in a for-fun cat project. After all I like. DO also care about scientific literacy #But it is funny to me that no one questions the comfrey LMAO #For context it's kind of like standing next to a nuclear reactor and then the audience points at a heavy object blocking a window and says-#''Hey isn't this a fire hazard?''#Like. Good that you're familiar with fire code! There is something even worse in the room with us <3

53 notes · View notes

bridgetbites · 6 years

Text

Bridget Bites : Hormones and Digestion

Hey Bridget, I just wanted to say that I absolutely love your posts on food and nutrition and think you should become a health coach and definitely do more in this field! You have such a balanced approach on eating and lifestyle and I really admire your non-judgmental and refreshing words of wisdom and advice. I have two questions and I hope this is okay: Firstly, it is related to hormones and menses- I have not been getting regular periods recently (there is nothing medically or gynecologically wrong with me I have had all the tests!) - and all the doctor advises is to eat more junk food and to gain more fat/weight but I have a healthy bmi and eat a balanced diet. A lot of models have healthy pregnancies and they are slim and healthy! From your nutrition studies or personal experience are there any natural ways to encourage it? Is there anything I could eat more of or any supplements I could take? It is very confusing out there as some people advise to eat more carbs whilst others advise more fat! My second question is related to digestive issues- from your blog I can see that you also suffer from gastro distress and I am wondering how you manage to follow a whole plant based high fibre diet. I actually find that vegetables and certainly fruits and fibre really make my ibs and pain worse and that it is often the more processed foods such as white breads and white rice and limited veggies and less healthy foods that sit better. However, I do not feel this is necessarily healthy. Any advice on how to follow a plant based vegan diet with chronic digestive issues would be much appreciated!

Hi! Thank you so much!! That means so much to me, I am really glad you find this helpful. And funny you should mention that, I am a newly certified health coach 😃

First off, I am definitely not a doctor. But I am a woman, and I have struggled with hormone issue, so I can at least guide you with what helped me. At the end of the day, if we don’t have enough fat, our periods suffer. BMI is not a great indicator of weight and health, as it doesn’t take into account body percentage. Muscle weighs more than fat, and so you could have a very high BMI but be at a much lower body fat percentage. Or the inverse; you could have a very low BMI but have a high body fat percentage. So I wouldn’t go by that as an indicator of health and weight.

The two things that have helped me in the past is changing the workouts I do and tweaking my diet. When I would grind out hours of cardio my period was not regular. It is very taxing on our bodies, and in small doses very good for you! But when cardio it is all you do, it does more harm than good. I swapped out seven day HIT sessions for twice weekly chilled runs, and walking everywhere. I never run more than five miles at a time, and I focus my running more on cruising and stress relief than hitting time goals. The rest of my workouts I spend doing muscle building exercises; things like Pilates, ballet, body by simone or yoga (if that is your thing!). I always make sure to include a couple of rest days a week, and I never push myself if I don’t feel up to it.

As far as diet is concerned, our hormones live in our fat tissue. If there is not enough fat, we do not create and store enough hormones. So I would advise you to eat more healthy fats. I have never been the person advocating for high levels of carbs – although it works for some people – due to my digestive issues (the second part of your question!). But I have found including an avocado a day, a handful of nuts and cooking in high quality olive oil to be the way to bring balance back to my hormones. Maybe give this a go!

Finally I would make sure that you aren’t taxing your adrenals too much. Try not to have coffee (sorry), take up meditation for stress relief, get enough sleep, and take time out for yourself. The jury is out on soy foods – some people say they are good for women’s hormones due to the phytoestrogens in them, some people say no. Soy upsets my digestion so I don’t have it regularly anymore. Use your instinct there, but if you do have it, don’t have more than a serving a day. And make sure it is all organic, non-GMO soybeans etc. In fact make sure all your food is as organic as possible, pesticides are nasty and can lead to endocrine disruption. Again, the last two points are contentious, but I am just saying what works for me 😃

Final note – ask your gyno to do a full thyroid check. Your symptoms could be signs of an imbalance there and you would be surprised at the amount of women who struggle with this unknowingly.

Onto your second question! My digestion sucks. It is the bane of my existence, and I am currently in another round of doctor’s appointments. I don’t have a huge amount of hope, because no healthcare professional has ever been able to tell me what is actually wrong. I am pretty sure the issue is emotional. It has been a tough month for me; I have made some huge decisions with regards to toxic people in my life, and am currently processing this change. My stomach plays up when I am dealing with trauma (this much I know at least) and so I am focusing on self-care during this period. Maybe try meditation, acupuncture, massage or yoga – anything that provides some stress relief.

What diet has helped a lot is the low-fodmap diet. It isn’t a cure all, and it can be tough to stick out, but if you can it provides a huge amount of relief. I now know what vegetables I cannot ever eat, and it usually isn’t what you would expect! Maybe give that one a go and see what happens. I would also look into soy and corn products and make sure they don’t upset your guts. When it comes to eating greens, nuts, grains and beans make sure you prepare them correctly. Steam your greens, and soak and properly cook your grains, nuts and beans. This can help with digestion. Papaya is great for your guts. And try looking into a macrobiotic diet – it focuses on whole grains which maybe you need more than most people!

And, if none of that works, then I would say start including some wild caught salmon or fish. These are all very real signals from your body that what you are doing is not working, and you owe it to yourself to listen. Life is too short to mess with your system so much that you can’t have kids, or spend every night in agony after eating, or have such a limited diet that you miss out on nutrition and happiness. Some people do not thrive on a vegan diet, and that doesn’t make you a bad person. So be truthful to yourself, be kind to yourself and honestly look at how your life is going. If there is nothing else to do, eat some fish and see how you go. You know enough about the planet to make the right choices as to the source of fish, and the planet needs you to be thriving, not just getting by 😃

I hope this helps!

Love

Bridget xxx

I love receiving your comments! - and if you have any specific questions don’t forget to ‘Ask Me Anything’ via the link here.

THANKS SO MUCH

Photograph | Simon Upton

3 notes · View notes

i-am-obscuram · 4 years

Text

Health Food Hypocrisy: The Truth Behind Losing Fat Part 3

This is the third part of the series on losing weight and keeping it off. In part 1 we discussed that there’s no such thing as a “one size fits all” dietary program as there are many factors when it comes to weight-loss. Part 2 addresses the frequently overlooked question of “Is it fat or inflammation?” Highlighting issues of allergies, intolerances, foods that cause inflammation, and how to diagnose them.

*Disclaimer: Always, consult your medical professional, do not consider this as medical advice! I am not an MD and I am not aware of your specific medical conditions, the information here is from the findings of my personal journey and research. If this is helpful to you, please consider contributing to Obscuram. Here's the facts behind those over hyped, over priced health food crazes that can end up doing more harm than good. Learn how to read a nutrition label, what it all means and what you can do to make better choices for your health and wallet. Be forewarned I’m about to open a can of reality on the health food industry, sorry not sorry.

Many sources agree on ditching processed foods from your diet, but then these products come along, they’re processed yet marketed as being the new perfectly healthy thing to eat! They’re expensive, really making your health and weight loss plan out to be something only the rich can afford; causing another blow to your self-esteem, and the worst part is… its all bullsh*t! As I mentioned previously in part 1 that even Oprah has had her struggles with her weight, but still hasn’t discovered combining all the factors necessary to successfully keep the weight off. That’s a clear sign that it’s not at all about money! Where do you begin on deciding what products are really healthy and what are not?

Read Nutrition Labels

Be sure to read the nutrition facts, especially if you want to limit calories, carbohydrates, sugar, salt, fat etc. Just as important are the ingredients listed especially when you have diagnosed allergies or intolerances as mentioned in part 2. If you don’t know what something listed is, either avoid the product or take the time to do a bit of research. The other day my daughter sampled a vegan product at a local grocery store and wanted it immediately, so we looked at the label which had fairly simple ingredients until one of the last ones which was nisin - not to be confused with niacin which is Vitamin B3 and a common ingredient added in fortified foods such as processed white flour. Nisin, is a substance produced by bacteria strain called Lactococcus lactis, that inhibits the growth of other strains of bacteria, preventing the product from going bad, or making it “shelf stable.” It is considered naturally derived and generally regarded as safe. That’s great, it’s lab grown “all natural,” yet the first question that came up is, “how does this affect or impact the beneficial bacteria in your digestive system?” Supposedly it doesn’t, but that’s from a manufacturer without a study attached to back up the claim. I’m going to go with my gut and avoid the product.

Avoid Health Food Hype

There are many health foods that make grandiose claims such as agave, touted as raw and low glycemic when it’s actually heated, processed, and although low on the glycemic scale at 30 its not advised for diabetics as it is straight fructose “Agave contains even more fructose than high-fructose corn syrup...The reason that high-fructose corn syrup gets such a bad rap is that it is metabolized differently than glucose. Fructose is metabolized by the liver: When the liver gets overloaded with fructose, it turns excess fructose into fat. Some of the fat can get trapped in the liver, contributing to a condition called fatty liver. Large amounts of high-fructose corn syrup have been linked to chronic diseases such as non-alcoholic fatty liver disease, insulin resistance, metabolic syndrome, obesity, and type 2 diabetes.”

Low calorie, no sugar Sweeteners

Thinking about switching to those low calorie, no sugar sweets? Think again. “Many seemingly healthy foods, such as protein bars and breakfast cereals, are labeled "sugar-free." Yet they contain dextrose, maltose, corn syrup, fruit juice concentrate and other hidden sugars. In fact, about 74 percent of packaged foods contain caloric sweeteners, according to a November 2012 report published in the Journal of the Academy of Nutrition and Dietetics.” See the image below for some common sweeteners to avoid. *Note that xlylitol actually has some health benefits with its potential drawbacks. Better sugar options include coconut sugar/coconut syrup, dates in moderation, and the no carb zero calorie, whole leaf powdered stevia - as noted below the extracts either contain dexterose or dairy derived lactose. Whole leaf Stevia powder can have a bitter flavor, there’s a bit of a learning curve to counter that and I find it best heated in tea or coffee.

vegan foods

Pre-made processed vegan foods, meals and meat replacement products are highly processed, contain a lot of sodium, sugar, and really should be limited or avoided. I’m mostly vegan and I tend to use a marinated tempeh (fermented soy product) or make my own seitan to replace meats. Seitan is not advised for those with gluten allergies, sensitivities or celiac diasese. I avoid tofu and non-fermented soy products as much as possible due to the estrogen hormone mimicker or phytoestrogen.

gluten-free

For those with gluten allergies, sensitivities or celiac diasese, there are now plenty of gluten free replacements! One of the newer ones on the market are made with cassava flour, also known as yuca. Here’s the downsides though it’s fairly nutritionally deficient with saponins and phytates blocking absorption, has more carbs and calories than ultra processed bleached white flour, and if not prepared correctly it’s highly toxic as it contains cyanide. “It is essential to peel cassava and never eat it raw. It contains dangerous levels of cyanide unless a person cooks it thoroughly before eating it.” A better option is garbanzo flour, also known as besan or gram flour in Indian markets where you will find it at a better price point. There are some tricks to using it for optimal texture and flavor. Other options include the pricier almond and coconut flours.

alkaline water

What about the alkaline water hype at $2 per gallon or more? Alkline water may actually aid in weight loss! Yet there’s still deception on this as its really easy and inexpensive to make, and you likely have all of the ingredients at home already.

1/4th teaspoon Baking Soda added to 1 Gallon of filtered water = alkaline water. Be sure to lower your salt intake to accommodate the addition of sodium present in baking soda. Also know that the store bought bottled alkaline water may not retain a shelf stable alkalinity.

Better Practices

Now that you feel like you cant eat anything, just do your best to remove the worst foods from your diet and replace them with healthier options. For example replace potato chips with nuts, seeds, carrots, bell peppers, or sugar snap peas. Other snack options include a banana or apple with a nut or seed butter; all of these suggestions are also great for a grab-and-go lifestyle. Ease your way into it and consider cooking or incorporating salads at home, as the payoff is well worth it. On the next post we will get into why mental health plays a major part in weight gain or preventing weight loss.

0 notes

cristinajourdanqp · 6 years

Text

A Primal Guide to Prostate Health

Many of you have asked about prostate health in a Primal context. Men are interested because they know men have a decent chance of getting prostate cancer. Women are interested because they’re worried about the men in their lives getting prostate cancer. Today, I’m going to delve deep into the topic, exploring the utility (or lack thereof) of standard testing, the common types of treatment and their potential efficacy, as well as preventive and unconventional ways of reducing your risk and mitigating the danger of prostate cancer.

Let’s go.

First, what does the prostate do, anyway? Most people only think about it in terms of prostate cancer.

It’s a gland about the size of a small apricot that manufactures a fluid called prostatic fluid that combines with sperm cells and other compounds to form semen. Prostatic fluid protects sperm against degradation, improves sperm motility, and preserves sperm genetic stability.

What Goes Wrong With the Prostate?

There are a few things that can happen.

Prostatitis

Inflammation of the prostate, usually chronic and non-bacterial. A history of prostatitis is a risk factor for prostate cancer.

Benign Prostatic Hyperplasia

Non-cancerous enlargement of the prostate. As men age, the prostate usually grows in size. This isn’t always cancer but can cause similar symptoms.

Prostate Cancer

What most of us are interested in when we talk about prostate health… After skin cancer, prostate cancer is the most common cancer among men and the sixth most common cause of cancer death among men worldwide. Yet, most men diagnosed with prostate cancer do not die from it; they die with it. The 5-year survival rate in the US is 98%.

That said, there is no monolithic “prostate cancer.” Like all other cancers, there are different grades and stages of prostate cancer. Each grade and stage has a different mortality risk:

Low-grade prostate cancer grows more slowly and is less likely to spread to other tissues.

High-grade prostate cancer grows more quickly and is more likely to spread to other tissues.

Local prostate cancer is confined to the prostate. The 5-year relative survival rate (survival compared to men without prostate cancer) for local prostate cancer is almost 100%.

Regional prostate cancer has spread to nearby tissues. The 5-year relative survival rate for regional prostate cancer is almost 100%.

Distant prostate cancer has spread to tissues throughout the body. The 5-year relative survival rate for distant prostate is 29%. Distant prostate cancer explains most of the prostate-related mortality.

What Are Symptoms of Prostate Cancer?

The primary symptom is problems with urination. When the prostate gland grows, it has the potential to obstruct the flow of urine out of the bladder, causing difficulty urinating, weak urine flow, painful urination, or frequent urination. This can also be caused by benign prostatic hyperplasia, a non-cancerous enlargement of the prostate.

What Causes Prostate Cancer?

A big chunk is genetic. People with “knockout” alleles for BRCA, which codes for tumor suppression, have an elevated risk of some forms of prostate cancer. That’s the same one that confers added risks for breast cancer.

Ethnicity matters, too. Men of Sub-Saharan African descent, whether African-Americans in the U.S. or Caribbean men in the U.K., have the highest risk in the world for prostate cancer—about 60% greater than other ethnic groups. White men have moderate risks; South Asian, East Asian, and Pacific Islander men have lower risks.

Testosterone has a confusing relationship with prostate cancer. Conventional wisdom tends to hold that testosterone stimulates prostate cancer growth, and there’s certainly some evidence of a relationship, but it’s not that simple.

In one study, men with low free testosterone levels were less likely to have low-grade (less risk of spreading) prostate cancer but more likely to have high-grade (higher risk of spreading) prostate cancer.

In another, testosterone deficiency predicted higher aggressiveness in localized prostate cancers.

In Chinese men, those who went into treatment with low testosterone were more likely to present with higher-grade localized prostate cancers.

Other studies have arrived at similar results, finding that “hypogonadism represents bad prognosis in prostate cancer.”

Many prostate cancer treatments involve testosterone deprivation, a hormonal reduction of testosterone synthesis. This can reduce symptoms and slow growth of prostate tumors during the metastatic phase, but prostate cancer tends to be highly plastic, with the ability to adapt to changing hormonal environments. These patients often see the cancer return in a form that doesn’t require testosterone to progress.

What About Testing?

If you have a prostate, should you get tested starting at age 40?

Not necessarily. The value of early testing hasn’t been established. Some researchers even question whether early testing is more harmful than ignoring it, and most of the research finds middling to nonexistent evidence in favor of broad testing for everyone. Early testing has a small effect on mortality from prostate cancer, but no effect on all-cause mortality.

PSA testing can also be inaccurate. PSA is prostate specific antigen, a protein produced by the prostate. It’s normal to have low levels of PSA present in the body, and while high levels of PSA are a good sign of prostate cancer—even years before it shows up in imaging or digital probes—they can also represent a false positive. Those two other common yet relatively benign prostate issues—benign hyperplasia and prostatitis—can also raise PSA levels well past the “cancer threshold.”

Other causes of high levels of PSA include:

Urinary tract infections

Recent sex or ejaculation

Recent, vigorous exercise

Certain medications.

In fact, if you have a PSA reading of 4 (the usual threshold), there’s still just a 30% chance it actually indicates cancer.

What About Treatment?

Let’s say you do have prostate cancer, confirmed by PSA and a biopsy (or two, or three, as needle biopsies often miss cancers). What next? Should you definitely treat it?

It’s unclear whether treatment improves survival outcomes. One study took men aged 50-69 with prostate cancer diagnosed via PSA testing, divided them among three treatment groups, and followed them for ten years. One group got active monitoring—they continued to test and monitor the status of the cancer. One group received radiotherapy—radiation therapy to destroy the tumor. And the last group had the cancer surgically removed. After ten years, there was no difference among the groups for all-cause mortality, even though the active-monitoring group saw higher rates of prostate cancer-specific deaths (8 deaths—in a group of 535 men— vs 5 in the surgery group and 4 in the radiotherapy group), cancer progression, and metastasis.

In another study of men with localized prostate cancer, removing the prostate only improved all-cause mortality rates among men with very high PSAs (more than 10). In men with lower PSAs, “waiting and seeing” produced similar outcomes as surgery.

Prostate removal also carries many unwanted side effects, like incontinence and sexual dysfunction. No one wants prostate cancer, but it’s no small thing to have problems with urination and sex for the rest of your life. Those are major aspects of anyone’s quality of life.

Before you make any decisions, talk to your doctor about your options, the relative mortality risk of your particular cancer’s stage and grade, and how the treatments might affect your quality of life.

How Can You Reduce the Risk of Prostate Cancer? 1. Inflammation is definitely an issue.

For one, there’s the relationship between prostatitis, or inflammation of the prostate, and prostate cancer that I already mentioned above.

Two, there’s the string of evidence linking anti-inflammatory compounds to reductions in prostate cancer incidence. For example, aspirin cuts prostate cancer risk. Low-dose aspirin (under 100 mg) reduces both the incidence of regular old prostate cancer and the risk of metastatic prostate cancer. It’s also associated with longer survival in patients with prostate cancer; other non-steroidal anti-inflammatories are not.

Third, anti-inflammatory omega-3 fatty acids (found in seafood and fish oil) are generally linked to lower rates of prostatic inflammation and a less carcinogenic environment; omega-6 fatty acids can trigger disease progression. A 2001 study of over 6,000 Swedish men found that the folks eating the most fish had drastically lower rates of prostate cancer than those eating the least. Another study from New Zealand found that men with the highest DHA (an omega-3 found in fish) markers slashed their prostate cancer risk by 38% compared to the men with the lowest DHA levels.

2. The phytonutrients you consume make a difference.

A series of studies on phytonutrient intake and prostate cancer incidence in Sicilian men gives a nice glimpse into the potential relationships:

The more polyphenols they ate, the less prostate cancer they got.

The more phytoestrogens they ate, the more prostate cancer they got. Except for genistein, an isoflavone found in soy and fava beans, which was linked to lower rates of prostate cancer. The Sicilians are eating more fava than soy, I’d imagine.

How about coffee, the richest source of polyphenols in many people’s daily diets? It doesn’t appear to reduce the incidence of prostate cancer, but it does predict a lower rate of fatal prostate cancer.

3. Your circadian rhythm and your sleep are important.

Like everything else in life, tumor suppression follows a circadian pattern. Nighttime melatonin—which is suppressed if your sleep hygiene is bad and optimal if your sleep hygiene is great—inhibits the growth of prostate cancer cells and reduces their ability to utilize glucose. One way to enhance nighttime melatonin is by getting plenty of natural, blue light during the day; this actually makes nighttime melatonin more effective at prostate cancer inhibition. On the other hand, getting that blue light at night is a major risk factor for prostate cancer.

4. Get a handle on your fasting blood sugar and insulin.

In one study, having untreated diabetic-level fasting blood sugar was a strong risk factor for prostate cancer. Another study found that insulin-lowering metformin reduced the risk, while an anti-diabetic drug that raised insulin increased the risk of prostate cancer. Metformin actually lowers PSA levels, which, taken together with the previous study, indicates a causal effect.

5. Keep moving, keep playing, keep lifting.

This has a number of pro-prostate effects:

It keeps you insulin sensitive, so neither fasting insulin, nor fasting glucose get into the danger zone.

If you’re doing testosterone suppression treatment, exercise can maintain (and even increase) your muscle mass, improve your quality of life, and increase your bone mineral density.

Oh, and do some deadlifts. Men with prostate cancer who trained post-surgery had better control over their bodily functions, as long as they improved their hip extensor strength. If you don’t know, hip extension is the act of standing up straight, of moving from hip flexion (hip hinging, bending over) to standing tall. It involves hamstrings, glutes, and the entire posterior chain. Deadlifts are the best way to train that movement pattern.

The prostate cancer issue is frightening because it’s so common. Almost all of us probably know someone who has or had it, even unknowingly. But the good news is that most prostate cancers aren’t rapidly lethal. Many aren’t lethal at all. So whatever you do, don’t rush into serious treatments or procedures without discussing the full range of options in a frank, honest discussion with your doctor.

That’s it for today, folks. Thanks for reading. If you have any questions, comments, or concerns about prostate cancer, feel free to chime in down below. I’d love to hear from you.

References:

Perletti G, Monti E, Magri V, et al. The association between prostatitis and prostate cancer. Systematic review and meta-analysis. Arch Ital Urol Androl. 2017;89(4):259-265.

Ilic D, Djulbegovic M, Jung JH, et al. Prostate cancer screening with prostate-specific antigen (PSA) test: a systematic review and meta-analysis. BMJ. 2018;362:k3519.

Brawer MK, Chetner MP, Beatie J, Buchner DM, Vessella RL, Lange PH. Screening for prostatic carcinoma with prostate specific antigen. J Urol. 1992;147(3 Pt 2):841-5.

Castro E, Eeles R. The role of BRCA1 and BRCA2 in prostate cancer. Asian J Androl. 2012;14(3):409-14.

Watts EL, Appleby PN, Perez-cornago A, et al. Low Free Testosterone and Prostate Cancer Risk: A Collaborative Analysis of 20 Prospective Studies. Eur Urol. 2018;

Neuzillet Y, Raynaud JP, Dreyfus JF, et al. Aggressiveness of Localized Prostate Cancer: the Key Value of Testosterone Deficiency Evaluated by Both Total and Bioavailable Testosterone: AndroCan Study Results. Horm Cancer. 2018;

Dai B, Qu Y, Kong Y, et al. Low pretreatment serum total testosterone is associated with a high incidence of Gleason score 8-10 disease in prostatectomy specimens: data from ethnic Chinese patients with localized prostate cancer. BJU Int. 2012;110(11 Pt B):E667-72.

Teloken C, Da ros CT, Caraver F, Weber FA, Cavalheiro AP, Graziottin TM. Low serum testosterone levels are associated with positive surgical margins in radical retropubic prostatectomy: hypogonadism represents bad prognosis in prostate cancer. J Urol. 2005;174(6):2178-80.

Banerjee PP, Banerjee S, Brown TR, Zirkin BR. Androgen action in prostate function and disease. Am J Clin Exp Urol. 2018;6(2):62-77.

Zhou CK, Daugherty SE, Liao LM, et al. Do Aspirin and Other NSAIDs Confer a Survival Benefit in Men Diagnosed with Prostate Cancer? A Pooled Analysis of NIH-AARP and PLCO Cohorts. Cancer Prev Res (Phila). 2017;10(7):410-420.

Russo GI, Campisi D, Di mauro M, et al. Dietary Consumption of Phenolic Acids and Prostate Cancer: A Case-Control Study in Sicily, Southern Italy. Molecules. 2017;22(12)

Russo GI, Di mauro M, Regis F, et al. Association between dietary phytoestrogens intakes and prostate cancer risk in Sicily. Aging Male. 2018;21(1):48-54.

Discacciati A, Orsini N, Wolk A. Coffee consumption and risk of nonaggressive, aggressive and fatal prostate cancer–a dose-response meta-analysis. Ann Oncol. 2014;25(3):584-91.

Dauchy RT, Hoffman AE, Wren-dail MA, et al. Daytime Blue Light Enhances the Nighttime Circadian Melatonin Inhibition of Human Prostate Cancer Growth. Comp Med. 2015;65(6):473-85.

Kim KY, Lee E, Kim YJ, Kim J. The association between artificial light at night and prostate cancer in Gwangju City and South Jeolla Province of South Korea. Chronobiol Int. 2017;34(2):203-211.

Murtola TJ, Vihervuori VJ, Lahtela J, et al. Fasting blood glucose, glycaemic control and prostate cancer risk in the Finnish Randomized Study of Screening for Prostate Cancer. Br J Cancer. 2018;118(9):1248-1254.

Haring A, Murtola TJ, Talala K, Taari K, Tammela TL, Auvinen A. Antidiabetic drug use and prostate cancer risk in the Finnish Randomized Study of Screening for Prostate Cancer. Scand J Urol. 2017;51(1):5-12.

Park JS, Lee KS, Ham WS, Chung BH, Koo KC. Impact of metformin on serum prostate-specific antigen levels: Data from the national health and nutrition examination survey 2007 to 2008. Medicine (Baltimore). 2017;96(51):e9427.

Galvão DA, Taaffe DR, Spry N, Joseph D, Newton RU. Combined resistance and aerobic exercise program reverses muscle loss in men undergoing androgen suppression therapy for prostate cancer without bone metastases: a randomized controlled trial. J Clin Oncol. 2010;28(2):340-7.

Ying M, Zhao R, Jiang D, Gu S, Li M. Lifestyle interventions to alleviate side effects on prostate cancer patients receiving androgen deprivation therapy: a meta-analysis. Jpn J Clin Oncol. 2018;48(9):827-834.

Uth J, Fristrup B, Haahr RD, et al. Football training over 5 years is associated with preserved femoral bone mineral density in men with prostate cancer. Scand J Med Sci Sports. 2018;28 Suppl 1:61-73.

Park J, Yoon DH, Yoo S, et al. Effects of Progressive Resistance Training on Post-Surgery Incontinence in Men with Prostate Cancer. J Clin Med. 2018;7(9)

0 notes

watsonrodriquezie · 6 years