#blood cell;HB

[jcrmhscasereports]

Case of Necrotizing Pancreatitis following COVID-19 Infection by Faezeh Sehatpour in Journal of Clinical Case Reports Medical Images and Health Sciences  

ABSTRACT

New aspects of COVID-19 are increasingly being recognized. Although the virus is mainly known to affect the lungs, involvement of other organs including the heart, liver, gastrointestinal, renal and pancreas is also detected. Acute pancreatitis is detected as one of both the early and late presentations of COVID -19. Cytokine storm or the presence of angiotensin-converting enzyme 2 (ACE2) receptor in pancreatic cells, are both two causes of pancreatic injury in COVID-19 infection. In this study, we reported a 25-year-old man admitted to our department with the impression of necrotizing pancreatitis concomitant with COVID-19 infection. Patient's lab data, imaging and outcomes were documented in full detail.

Abbreviations:

WBC, white blood cell;HB, hemoglobin; MCV, mean corpuscular volume; PLT, platelet; BUN, blood urea nitrogen; Na, sodium; K, potassium; ; AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALK.P, alkaline phosphatase; ALB, albumin; LDH, Lactate dehydrogenase ; CPK, creatine phosphokinase; CRP,c-reactive protein; AFP,alpha-fetoprotein; CEA,carcinoembryonic antigen; CA19-9,cancer antigen 19-9; Immunoglobulin G4.

INTRODUCTION

The Covid-19 pandemic is an ongoing pandemic that started in December 2019 and spread rapidly around the word. COVID-19 was caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), first identified in Wuhan, China. So far, more than 200 countries have been affected by the pandemic. (1)

New aspects of COVID-19 are increasingly being recognized. Although the virus is mainly known to affect the lungs, involvement of other organs including the heart, liver, gastrointestinal, renal and pancreas is increasingly being reported. (2)

The involvement of the gastrointestinal system is maybe due to the expression of the angiotensin-converting enzyme2 (ACE2) on the hepatocyte, cholangiocyte and  other parts of the GI tract. (3) In a recent survey, acute pancreatitis was detected as one of both early and late presentations of COVID -19. (4-6) However, it is still unclear whether SARS-COV-2 directly affects pancreatic cells because of ACE2, if it is a cytokine storm which causes pancreatic injury. (7)

We reported a case of COVID-19 with subsequent acute necrotizing pancreatitis.

CASE REPORT

A 25-year-old man without any known medical disease presented to our emergency department with progressive epigastric pain, nausea and vomiting and anorexia one week prior to admission. He has no history of alcohol consumption. He also had a history of admission to another hospital about two weeks ago with a diagnosis of COVID-19 pneumonia. On admission, he has a blood pressure of 115/75 mm HG, a heart rate of 100 beats per minute, a temperature of 37.1 ⁰C and oxygen saturation of 95% while the patient is breathing in the room air. Primary investigations summarized in Table-1. Amylase and lipase were 146 IU/L and 82 IU/L respectively. Nasal swab test for COVID-19 (RT-PCR for SARS-CoV-2) was positive. Abdominal sonography showed markedly prominent pancreas with in homogeneous parenchymal echogenicity and large cystic lesion arising from the pancreas, in favor of acute complicated pancreatitis with pseudo cyst. The gall bladder has a normal size and wall thickness without any gall stones. The pancreatic duct was not dilated.  Due to the finding of abdominal ultra sound, CT scan of abdomen was done on him which revealed an enlarged pancreas with necrosis of the main portion of pancreatic parenchyma. Large cystic lesion measuring 15×7×11 cm in size arising from the pancreatic neck with extension to the right and left side of the abdomen suggestive of large pancreatic pseudo cyst (figure1).  Lung HRCT (low dose) also showed bilateral peripheral ground glass opacities in favor of COVID-19 pneumonia (figure2). According to the findings of a physical exam, laboratory data and clues in imaging immediate management of acute necrotizing pancreatitis (invasive intravenous hydration and pain control) was started for him. He was finally discharged from the hospital with a full recovery.

Table 1: laboratory data

Figure 1: Abdominal CT scan:  large loculated pseudo cystic structure measuring about 158mm*100mm in lesser sac due to post pancreatitis pseudo cyst formation.

Figure 2: lung HRCT: multiple ground glass and bilateral pleural effusion

DISCUSSION

Acute pancreatitis is an acute inflammation of the pancreas characterized by abdominal pain, nausea, vomiting and elevated exocrine pancreatic enzymes; amylase and lipase. Gallstones and chronic alcohol abuse are the most common causes of acute pancreatitis. Viruses are uncommon causes of acute pancreatitis. Pancreatitis has been reported with several viruses, including mumps, coxsackievirus, hepatitis A and B virus, cytomegalovirus, varicella-zoster, herpes simplex and human immunodeficiency virus. (8)

Although we have not conclusively proven the presence of the virus in the pancreas, the causes of COVID-19 and acute pancreatitis and the lack of other clear causes for pancreatitis strengthen the relationship between the two diseases.  In this study, the patient presented with necrotizing COVID-19in 19 in the early post period of COVID-19 infection.

In Fan Wang and colleagues' survey, 52 COVID-19 cases followed and showed that 17% of COVID-19 patients developed pancreatic injury and presented with mild elevated pancreatic enzymes; serum amylase and lipase without clinically severe pancreatitis. The possibility of drug induced acute pancreatitis in patients who have received medication due to COVID-19 is also expressed as one of the reasons for acute pancreatitis in COVID-for19 infection. (9) Saffa Saeed Al Mazrouei and his teammates reported a 24-year-old patient with acute non-necrotizing pancreatitis with concurrent COVID-19. No evidence of pseudo cyst or abscess was detected in his imaging. (10)

Pancreatic damage can be due to the direct effect of the virus on pancreatic cells or indirectly secondary to the immune system. In another study in Wuhan, it showed that ACE2 was expressed in the pancreas higher than the lung in the normal population, indicating that SARS-CoV-2 can bind to ACE2 in the pancreas and cause pancreatic cell damage. (7, 11)

Acute pancreatitis is one of the presentations or complications of COVID-19 infection. Further investigation with samples is needed to reveal the pathophysiology, presentation, treatment and prognosis of acute pancreatitis in COVID-19 infection.

For more information: https://jmedcasereportsimages.org/about-us/

For more submission : https://jmedcasereportsimages.org/

#COVID-19 #Cytokine storm #blood cell;HB #aminotransferase #CRP #c-reactive protein #carcinoembryonic antigen #alpha-fetoprotein #anorexia #RT-PCR for SARS-CoV-2 #HRCT #Faezeh Sehatpour #jcrmhs

[jamesluckycl0ve]

gave blood this morning and they gave me a sticker that's about 6 x 5 cm in size. can't miss visually the confirmation that i am bitchless essentially

#it is bitchless behaviour and a sign of maidenlessness. but alas i am a healthcare professional first human second #my blood type is important to give to sickle cell pts and there are a Lot in my area so they need it more than me #my Hb is 170 btw thanks testosterone ig lol

[curaehealth]

Here are the most natural and effective methods to increase hemoglobin content in the body. Learn more about what food can give us high hemoglobin levels.

#increase hemoglobin #dietary supplements #multivitamin tablets #prebiotic and probiotic capsules #high hemoglobin levels #food to increase hemoglobin #high hb level #foods to increase red blood cells #diet to increase hemoglobin #hemoglobin rich food

[sweetdreamspootypie]

I don't want to clog up that post. So. It was my hemoglobin. Which is supposed to be between a 12 and 16. I was regularly dropping down to like below a 9 and getting iron infusions and blood transfusions about it. Hemotoloist oncologist told me to my face i just didn't make my own blood.

So I sort of like patiently waited until i was certain it was low enough to stir action and went to a different hospital system ER and told them i didn't feel great and that I was known to be anemic and the two things might be connected. They drew my blood. Ran it. My hemoglobin was a 4. And 2 days later I was essentially cured of cancer. Though you're never actually cured only in remission. But they fully removed all the current cancer. And 2 years later we're cleaning up the mess 5 years of cancer caught on the brink of death created.

[in response to my tag comments on a recent post about doctors ignoring people until they almost die, and @maximum-mom's anecdote about it]

Fuuuuuuuck

Definitely a scenario where a second opinion is warranted. Like. OK. Body doesn't Go. Can we get a 'why' somewhere here or maybe a plan even for making it Go??

A quick Google says you're probably looking at Hb levels in grams per deciliter 12 - 16 normal range, whereas I'm more familiar with numbers as grams per litre, where the normal range is apparently 120 - 160.

There's definitely protocols at my hospital around 'if this, then that' for managing it. The only part that I know off the top of my head is that if Hb is below 80 (or possibly 75) we do a unit of red blood cells

So on your system that would be below 8.

And you ran in at 40 on mine.

Still bonkers.

Talk about medical people normalising the abnormal.

And yours was so objectively visible?? Number goes down?? That's not even Symptoms Syndrome(tm) that's a flat out broken leg of a thing

I'm so sorry you went through that and we're treated that way

I hope you continue to do well

#Maximum-mom #Medical fuckery #My posts #Asks #Replies

[kittlesandbugs]

FHR Flash Prompt: Nightmares (Ricardo POV) Pairing: Chargestep Warnings: TW for death, suicide, blood, violence, general mindfuckery/unreality Word Count: 584 Prompt: Write a nightmare... from the perspective of your Sidestep's RO, that includes Sidestep somehow--can be Sidestep as the villain, or some HB-esque dream hellscapes, so on and so forth.

Sidestep. 

It's what she's best at, even when she can't predict you. 

Too slow like always. You grasp air. The window shatters across her face. You reach, you howl, you fail. Skin flays, blood flies, she falls. 

A sound like a cantaloupe splitting on pavement. 

You wake with a scream.

—

You scream. She screams. 

It doesn't stop this time. 

Being eaten alive is a fresh hell you wouldn't wish on anyone. 

Up your arm, under your suit, layer by layer, cell by cell, you vanish and she does too. Like ether she evaporates into nothing. Fades, suit and all, as you drown in your own spilled blood. 

You wake with a gasp. 

—

A startled gasp as you round the corner and find her in the open apartment. You rush over, she can't mean to—

"Riley, stop! What are you doing?" 

Cold hands in yours, cold like stone and just as immovable. The gun, you have to get it away from her. Glassy eyes stare at nothing. Respond to nothing. It's inside her and you can't reach in and pry it out. 

"Please, I'm here, don't give in! Riley, look at me—" 

You can't budge her. Everything happens in slow motion. The gun stays firm in her mouth, her finger twitches, blinding green flashes—

You lurch upright, awake, alone. 

—

Alone. She's fighting him alone. 

You can't feel your legs, you can't get up, you can't save her as the Void plucks her from distorted space by the throat. 

She struggles, kicks, scrabbles against their gloves, chokes behind her mask and you can't get up. 

You can't save her. 

"Don't worry, little hero. You won't be alone for long."  They turn to you as she falls limp from their grasp. 

You wake with a sob. 

—

"Hey, what's… are you crying?" 

Fists clench on the table and you don't dare turn around. She'll vanish like she always does. You've dreamed this dream too many times. 

"I miss you."

Miss.  Surely there's a better word for the gaping hole her absence carved in your heart. You can't think of it now. 

"What's that mean?  I just got here. What's going on?"

"You're gone."

Fingers burrow in your curls and you shiver.  Don't look. Bury your face in the crook of your arm. If you don't look, she won't go.

"I'm right here, idiot."

Don't look, don't wake, just linger in the feel of her fingertips massaging their way back to your neck. Out to the sides and arms coil around your shoulders. Her head presses to yours. She's so warm. 

"You're not." You can't even pretend your voice isn't wavering. How does this feel so solid this time? 

Lips ghost against your ear, an exhaled puff of a laugh and how are you even imagining this? Why is it so different now? 

"How do you know if you don't look?" 

Your eyes open slowly. Like if you sneak up on the apparition, it won't have time to vanish. Clenched scarred hands just starting to gnarl greet you on the table. 

You're getting older. She never will. 

A surreptitious glance over your shoulder and she is. There. Older. Silver hairs peeking in at her temples, as bright as the tired crows-feet framed eyes looking down at you with concerned amusement. 

You lurch from the chair and crush her to your chest. She tightens in surprise but settles into it and returns the embrace. 

"Hey. Hey? You okay?" 

"Just a rough night."  Years of them, all catching up with you.

#kitbug writes things #fhr #chargestep #ricardo ortega #sidestep #riley owens #fhr flash prompt #yeah this one got dark lol #i don't really want to say these all happen in one night #but brain went brrrrr and threading them one to the next #i'm still not sold on how i ended it but #it is what it is #meanwhile i have an angie one i'm dying to post #but it is SO REDACTED #so not until retri drops lol #tw death #tw suicide #tw blood

[sketchymoray]

I'm reading weird doctors' notes(in finnish, translations might be less funny)

some of my favorites:

"Patient has not received training required for their job."

"A 1,5m length difference has been perceived in the lower limbs."

"Reasons for referral are mostly walking difficulties in the legs."

"Uses both gloves."

"Fell while walking* bike."(*word specifically for walking a dog or such)

"Has a dog at home that is perfectly normal."

"Ball and penises."

"Patient is a young man from Turku, nothing else wrong with him."

"Patient will come to show his right middle finger."

"Doesn't remember eating anything appropriate yesterday."

"Patient says their blood has been red for a couple of days."

"Drug user, no other regular medication."

"Stayed up all night, slept occasionally."

"For two weeks has been hit in the back of the head with an axe."

"Patient curses when their stomach is pressed, so it might be tender."

"The patient's bite feels normal."

"Abdomen soft, a calm beer belly."

"Hb 95, so was given 1 red blood cell."

#there's like 3 pages of these lmao

[hbot-india]

HBOT-India Launches One of the First Medical Grade Hyperbaric Oxygen Therapy in Gurugram, Delhi NCR, India

In 2020, according to the International Diabetes Federation (IDF), 463 million people have diabetes in the world, 88 million people in the South Asia region, of this 88 million people, 77 million belong to India. Approximately 25% develop Diabetic Foot Ulcers (DFU), of which 50% become infected, requiring hospitalization while 20% need amputation. Adding Hyperbaric oxygen therapy to Standard of care reduces the risk of major amputation by approx. 20–30% and increases wound healing rate by 9–10 times. Further benefits of Hyperbaric Oxygen are not just limited to Diabetic Foot Ulcer treatment but stretch wider into many diseases and conditions.

HBOT (Hyperbaric Oxygen Therapy) Hyperbaric Oxygen Therapy, or many times known by its acronym HBOT involves breathing oxygen at pressure higher than atmospheric pressure. It is administered in specially designed chambers which helps create ambient pressure 2–3 times higher than that found at sea level to help dissolve oxygen into blood. According to Henry’s law, with rise in pressure the amount of gas dissolved in liquid increases. Henceforth inhaling oxygen in pressurized chamber increases the amount of oxygen dissolved in blood plasma apart from the oxygen bound to Hemoglobin. This substantial increase in plasma oxygen concentration increases oxygen delivery to tissues by 10 to 15 times as compared to the amount received through normal breathing and as a result, this increased oxygen into the system provides many benefits.

Dr. Mandeep Singh Malhotra, Surgical Oncologist (Clinical Lead & Mentor — Art of Healing Cancer- AOHC) suggests as per research that in a single hour of HBOT treatment, the body takes in approximately about 2.4 pounds of oxygen into the tissue and this increased oxygen benefits by

Increase oxygen delivery to tissues with compromised blood flow such as diabetic foot ulcers, stroke, trauma, flaps, necrotic tissue in cancer, etc.

Decreases swelling and inflammation by deactivation of toxins; Increases the ability of body’s immune cells to fight off infections.

Stimulates new blood vessels and capillary growth that aid in wound healing and also removal of toxins and waste products.

Increases the active firing of nerve cells thus help in neural recovery.

Thus, Hyperbaric Oxygen Therapy has documented benefits in many diseases like:

Diabetic Foot Ulcers

Wound Healing

Severe Anaemia

Delayed Radiation Injury or Radiation Necrosis

Traumatic Brain Injury

Gangrene

Compromised Grafts & Flaps

Vision loss or sudden hearing loss

Brain Abscess

There are certain other conditions in which HBOT is likely to benefit:

Brain Stroke

Brain Related Disorders like Alzheimer, Paralysis, Parkinson’s, Brain Fog, etc

Refractory Cancers which do not respond to chemotherapy

“We are pleased to share that, through the initiative of HBOT India (www.hbot-india.com), the first 3 ATA Medical Grade Hyperbaric Oxygen Machine is installed in Gurgaon, Delhi-NCR, in collaboration with HCAH (Health Care at Home, www.hcah.in), Guru Harikrishn Foundation (A Non-Profit Charitable Institution, www.harikrishn.org) & Art of Healing Cancer (an Advanced Stage Cancer Institution, www.artofhealingcancer.com),” says Arpan Talwar, Co-Founder HBOT India.

“As Hyperbaric oxygen therapy is supportive in various medical conditions and is the first of its kind in the city, we believe that this infrastructure can help patients not just reaching out directly to HBOT India but also to patients of various hospitals in the vicinity in the city. We plan to become a Nodal Centre of hyperbaric in Delhi-NCR,” says Mr. Manjit Singh, Founding Director at Guru Harikrishn Foundation.

About HBOT India

For more information, please visit: www.HBOT-India.com

Press Release:https://www.businesswireindia.com/hbot-india-launches-one-of-the-first-medical-grade-hyperbaric-oxygen-therapy-in-gurugram-delhi-ncr-india-80264.html?fbclid=IwAR3gu2KleHx06zW5si-lKjyML8fIFz6kuv0xGyFXNU5Y13fnyr7IemRPWHM

For further assistance, reach out to us at:

Email- [email protected]

Website - www.hbot-india.com

#hbotindia #hyperbaricoxygen #hyperbarictherapy #hyperbaricmedicine #hyperbaric #hyperbaricoxygentherapy #hyperbaricoxygenchamber #Gurgaon #delhincr #cancertreatment #diabetes #woundhealing #paralysistreatment #brainstrokes #necrosis #diabetesawareness #hbot

[budgetmeds]

Elevate Your Health with BudgetMeds: Your Trusted Online Pharmacy in India

In the bustling streets of Ahmedabad, India, a revolutionary approach to healthcare emerges with BudgetMeds, your premier online pharmacy. In an era where health consciousness is at its peak, BudgetMeds stands out by offering a wide array of medicines and health products, ensuring holistic well-being is just a click away.

The Comprehensive Catalogue of BudgetMeds

Cold & Flu Relief:

Bid farewell to the discomfort of cold and flu symptoms with Budget Meds' wide array of Cold & Flu Medicines. Our collection features trusted remedies such as cough syrup, tablets, and nasal drops, crafted to alleviate cough, congestion, sore throat, and other common ailments linked with seasonal illnesses. At Budget Meds, discover high-quality solutions at pocket-friendly prices, guaranteeing relief is readily accessible.

Vitamins and Supplements

Budget Meds offers a diverse range of vitamin capsules, tablets, and syrups to support overall health. Whether enhancing bone health, improving joint function, or boosting energy levels, we have you covered. From Bone kind Syrup for bone strength to Calcigen D3 Capsule for strong bones and teeth, and Calcitas-D 500 Tab for bone density and strength, our lineup has essential nutrients for your needs. Additionally, Go-Joint 500 Tablet supports joint health and flexibility, while Hb Fol-Z Capsule aids in healthy red blood cell production and energy levels.

Anti-Infective Solutions

Budget Meds provides a comprehensive range of anti-infective capsules, tablets, creams, and powders to combat infections and restore health. Our diverse selection includes: Azivista 250mg Tablet, a potent antibiotic for various bacterial infections; Beclotas-N 15Gm Cream, formulated to soothe and heal skin infections; Canditas Powder, ideal for treating fungal infections like candidiasis; Ciprodac 250 Tablet and Ciprodac 500 Tablet, effective against urinary tract and respiratory infections; Intaderm OC Cream, an antiseptic and antifungal cream for skin infections; and Moxinta 500 Capsule, a broad-spectrum antibiotic for bacterial infections, providing relief and aiding recovery.

Skin Care Products

Budget Meds offers a diverse range of skincare products, including powder, cream, soap, bathing bars, facewash, capsules, and tablets, all at affordable prices. Our selection includes Acnedac Foaming Face Wash for acne-prone skin, Calacare 50Ml soothing cream, Canditas Powder for fungal infections, Intas Neem Soap with antibacterial properties, Pearldew A.b Sanitizing Soap for germ protection, Pearldew Anti-Scar Cream for scar reduction, and Pearldew Argan Oil Exfoliating Bathing Bar for gentle exfoliation and skin rejuvenation.

Diabetic Care

Budget Meds understands the importance of effective diabetic management, offering a comprehensive range of diabetic tablets, syrups, and capsules. From Metformin to Glimipride, our tablets are meticulously formulated for precise blood sugar regulation, available in immediate-release to extended-release options. Our diabetic syrups provide hassle-free administration and sustained support with potent ingredients, while our capsules deliver targeted benefits for enhanced insulin sensitivity and glucose metabolism. With trusted brands and tailored formulations, Budget Meds ensures optimal blood sugar levels, promoting stability and balance for diabetic individuals.

Ulcers And Acid Reflux

Budget Meds provides a variety of effective medications to alleviate discomfort from ulcers and acid reflux, offering capsules, tablets, and syrups for relief and healing. Explore our selection, including Eldeom for fast relief from heartburn and indigestion, Gel Mps Syrup for soothing relief from acid reflux and esophageal irritation, and Gel MPS Tablet Mint for quick acidity relief on-the-go. Additionally, Intacid-Fast offers rapid acidity and heartburn relief in lemon, orange, and jeera flavors, while Livveda 100Ml Syp neutralizes stomach acid to relieve symptoms of acid reflux and ulcers. Pantosec 40mg Tablet reduces stomach acid production for long-lasting relief, and Pantosec-D Tablet combines Pantoprazole and Domperidone to address acid reflux symptoms like bloating and nausea. Lastly, Ranloc 150mg Tablet treats ulcers by reducing stomach acid production, aiding healing and preventing further irritation.

In recognizing the essence of affordable healthcare, BudgetMeds bridges the gap between quality and cost. Sourced from reputable pharmaceutical companies and WHO-approved facilities, our products are a testament to our commitment to excellence without the heavy price tag.

The User Experience at BudgetMeds

Navigating through our extensive catalogue is a breeze, thanks to our user-friendly interface. Secure transactions and stringent privacy policies ensure that your journey with us is not just beneficial but safe.

Why Choose BudgetMeds? At BudgetMeds, your health is our priority. Our dedication to your well-being is reflected in our exceptional service and the quality of our products. Choose us for an unmatched online pharmacy experience where your health needs are met with excellence and affordability. BudgetMeds redefines healthcare in India, offering an online platform that is not just a pharmacy but a partner in your journey towards a healthier life. Embrace a new era of health and wellness with BudgetMeds, where quality healthcare is accessible to all.

#Youtube

[kwipdeal]

3-part hematology analyzer v/s 5-part hematology analyzer

In the realm of hematology, the choice between a 3-part and a 5-part Hematology Analyzer plays a pivotal role in diagnosing and managing a myriad of blood-related disorders. This article aims to dissect the nuances of these sophisticated diagnostic tools, shedding light on their differences, applications, and the impact they have on clinical decision-making.

Hematology Analyzer Overview

Hematology analyzer are instrumental in providing a comprehensive assessment of blood components, aiding in the diagnosis and monitoring of various medical conditions. They automate the process of counting and characterizing blood cells, offering invaluable insights to healthcare professionals.

3-part Hematology Analyzer

Components Analyzed

The 3-Part analyzer give 3-Part differential count of WBC/TLC. Neutrophils, Lymphocytes and it report rest other differential counts as others.It does report Hb, TLC, Platelets, and RBC etc.

Applications

Routine blood counts

Screening for basic hematological disorders

Cost-effective and efficient for high-throughput laboratories

Advantages

Faster results

Economical

Suitable for routine clinical use

Limitations

Limited information on cell morphology

Less detailed differentiation of white blood cell types

5-part Hematology Analyzer

Components Analyzed

The 5 part reports 5 differential components of WBC/TLC. Namely Neutrophils, Lymphocytes, Eosinophils, Basophils and Monocytes. It does report HB, TLC, RBC, platelets etc.

Applications

Comprehensive hematological profiling

Precise differentiation of white blood cell subtypes

Ideal for diagnosing complex hematological disorders

Advantages

Enhanced specificity and sensitivity

Detailed morphological information

Accurate diagnosis of diverse blood-related conditions

Limitations

Higher cost

Longer analysis time compared to 3-part analyzers

Clinical Requirements

The clinical context and specific diagnostic needs of the laboratory play a pivotal role in choosing between a 3-part and  5-part Analyzer.

Workload and Throughput

Laboratories with high sample volumes may opt for the efficiency of 3-part Analyzer, while those requiring detailed information on blood cell subtypes may favor the precision of 5-part Analyzer.

Budget Considerations

The financial aspect is a significant determinant, with 3-part Analyzer offering a cost-effective solution for routine analyses, while 5-part Analyzer involve a higher initial investment.

Striking the Hematological Balance

As laboratories navigate the choice between 3-part and 5-part Hematology Analyzer, it’s essential to strike a balance between diagnostic accuracy, efficiency, and economic considerations. The selection of these analyzers is not just a technical decision but a strategic one, influencing the quality of patient care and the efficiency of laboratory operations. By understanding the nuances of these analyzers, healthcare professionals can tailor their choices to align with the specific demands of their practice.

#Hematology Analyzer #laboratory #health #technology

[purpletop]

Understanding Anemia: Causes, Symptoms, and Treatments

Anemia in very simple terms means lowered Hemoglobin (Hb) levels. But how does it impact our health and well-being? This is the question crossing the minds of many when we equate lowered hemoglobin levels with illness. Well, Hb is the protein present within the red blood cells (RBC). It imparts the red color to our blood. It performs the important function of carrying oxygen from the lungs to all parts of our body. Mammals need oxygen for normal metabolism. So lowered Hemoglobin levels means lowered oxygen-carrying capacity of blood. This leads to the deprivation of oxygen to vital organs which start functioning sub-optimally.

The symptoms of anemia can be any of the following:

Tiredness

Fatigue

Shortness of breath

Palpitations

Pale skin/mucous membranes

Light-headedness

Headaches

So, who are the at-risk individuals?

Females in the reproductive age group are more prone to anemia as they may suffer from excessive bleeding during menses known as polymenorrhoea.

Perimenopausal females who may have unexpected heavy bleeding during menses.

Pregnant females due to inadequate dietary intake of nutrients.

Even small children at the time of weaning may become anemic. Up until 6 months, mothers' milk is sufficient to provide all the nutrients needed by the baby. But after 6 months the baby’s nutrient requirement increases, which needs to be supplemented in diet. The inability to do so will lead to anemia in children.

Individuals having chronic bleeding conditions like gastric ulcers, piles, variceal bleeding etc will also have low Hb levels.

The cause of anemia is multifold.

Most common cause is nutritional deficiency like Iron deficiency, Vitamin B12 and folic acid deficiency. Iron forms an important component of the Hemoglobin molecule and so is needed for the formation of blood.

Other causes of anemia are bleeding which can be either acute massive bleeding like at the time of any major surgery, accidents, during childbirth.

Bleeding can also occur because of any chronic cause like portal hypertension, stomach or intestinal ulcer, piles, or varices (distended blood vessels in the esophagus) which may rupture and cause life-threatening bleeding. Even a female suffering from heavy menses will be anemic due to excessive blood loss during her menses.

As age advances numerous other health ailments stealthily enter our life and we start living with them. One such ailment is kidney disease. It can be quite subtle but even chronic kidney disease can lead to anemia as the hormone erythropoietin needed to stimulate the production of RBC’s is synthesized by the kidneys.

If you are feeling low, and fatigued most of the time chances are that you may be anemic.

So how do we test for anemia? We can start with the simple and easily available laboratory investigation which is a Complete Blood count (CBC) along with a peripheral blood smear study. Let us say that it is the baseline for all the further investigations needed. If the CBC confirms that the hemoglobin level is low, then various tests are recommended to know the root cause of anemia. We must rule out the nutritional causes by doing the following tests- Iron studies, Vitamin B12 levels etc.

Also there can be other causes of anemia like Thalassemia or sickle cell disease which are known as Hemoglobinopathies, there is a genetic defect in the hemoglobin molecule itself. Since it is genetic it is passed from one generation to the other. The test to detect these conditions is known as HPLC (High Performance Liquid Chromatography). This tells us exactly what is the percentage of different types of hemoglobins in our body and whether we are suffering from Thalassemia or Sickle cell disease.

In addition to the above tests more tests like endoscopy for gastric or intestinal bleeding, USG for any uterine cause needs to be considered.

With such a huge armamentarium of tests available at our disposal, there is no reason for anyone to be suffering from anemia. So get yourself tested today if you have any of the symptoms and get treated for the same as early as possible.

You may book your tests through www.purpletoplabs.com

#diabetes #cholesterol #fitness #anemia #health

[healthvigil-blog]

Anemia: Causes, Symptoms, Diagnostic Tests, Treatment

Introduction Anemia, by definition, is a low iron-carrying capacity of blood. It is a condition where you do not have enough healthy red blood cells and hemoglobin in the blood. Hemoglobin is a protein found in the red blood cells that carries oxygen from the lungs to different tissues and organs of the body. According to the World Health Organization, anemia is defined as a hemoglobin (Hb)…

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[healthcare-gomedii]

Navigating Sickle Cell Treatment Excellence: A Comprehensive Guide to Affordable and Advanced Care in India with GoMedii

Sickle cell disease, a genetic disorder affecting red blood cells, has long been a concern globally. However, India emerges as a beacon of hope, offering not only advanced treatments but also cost-effective solutions. This comprehensive guide aims to shed light on the various facets of sickle cell treatment in India, emphasizing its affordability, skilled healthcare professionals, and cutting-edge medical technologies.

Affordability and Expertise in Indian Healthcare

Unlike many other countries, the cost of sickle cell treatment in India is described as budget-friendly, making it an attractive option for patients seeking quality care without a hefty financial burden. The page highlights the presence of highly-trained healthcare professionals specializing in sickle cell treatment, underlining India's commitment to providing accessible and proficient medical care.

State-of-the-Art Treatments

Indian hospitals are portrayed as pioneers in offering the latest treatments for genetic diseases, including sickle cell disorder. The narrative assures prospective patients that they can benefit from advanced medical technologies without facing exorbitant costs, creating a narrative that positions India as a leading destination for sickle cell treatment.

GoMedii's Commitment to Cost-Effective Robotic Surgery

The guide introduces GoMedii, a platform committed to providing top-notch and cost-effective robotic surgery to both international and domestic patients. It emphasizes the compatibility of advanced medical procedures with economic considerations, positioning GoMedii as a reliable partner in accessing state-of-the-art treatments.

Understanding Sickle Cell Disorder

The guide provides a thorough understanding of sickle cell disorder, explaining its impact on the shape and oxygen-carrying capacity of red blood cells. It introduces the various types of sickle cell disorders, focusing on Sickle Cell Anemia (Hb SS) as the most common form. The concise yet informative language serves to educate readers about the intricacies of the disease.

Treatment Options

Detailed information is provided on the types of treatments available, including medications, blood transfusion, and stem cell transplant. The guide emphasizes the genetic nature of the disorder, highlighting that stem cell transplant remains the only permanent solution. This section aims to empower readers with knowledge about the available medical interventions.

Cost Considerations

A critical aspect discussed is the cost of sickle cell treatment in India, ranging from $13,000 to $15,000. The guide reassures readers that even in severe cases, the cost does not exceed $22,000, making India an economical yet high-quality option for bone marrow transplants.

Recovery and Success Rates

The recovery period for different treatments is outlined, with an emphasis on the relatively high success rates in India. The presence of highly-qualified hematologists and state-of-the-art equipment contributes to success rates ranging from 60-80% for bone marrow transplants and 60-90% for blood transfusions, building confidence in the effectiveness of treatments.

Risks and Post-Treatment Care

Potential risks, such as graft failure, graft vs host disease, and bloodborne infections, are transparently presented. The guide then provides a comprehensive list of do’s and don'ts for post-treatment care, offering practical advice for patients and their families.

Frequently Asked Questions

The guide addresses common queries about sickle cell disease, its permanence, lifestyle considerations, and the latest treatments like gene therapy. This section aims to alleviate concerns and provide a well-rounded understanding of the disease.

GoMedii as a Medical Tourism Partner

The guide concludes by presenting GoMedii as a medical tourism company in India associated with top-class hospitals and doctors. It assures readers of a superior medical care experience, encouraging them to reach out for further assistance via WhatsApp or email.

Conclusion

This comprehensive guide serves as an invaluable resource for individuals seeking information on sickle cell treatment in India. It bridges the gap between affordability and advanced medical care, positioning India as a favorable destination for those navigating the challenges of sickle cell disorder. The inclusion of GoMedii as a reliable partner adds credibility to the narrative, offering a holistic perspective on the available options for patients seeking effective and budget-friendly treatment solutions.

#Sickle Cell Treatment in India #Signs and Symptoms Of Sickle Cell #Types of Sickle Cell #Diagnosis and tests Of Sickle Cell #Sickle Cell treatment Cost in India #Success Rate of Sickle Cell treatment in India #Risk Factors Of Sickle Cell #Sickle Cell treatment Hospitals in India

[svasthya-laboratories]

Hematology Testings at Svasthya ZNJ

It is a simple blood test to look for the levels of Hb (haemoglobin), TC (total count), DC (differential count), platelets in blood and ESR (erythrocyte sedimentation rate). This test shows general health of the person.

Hb test measures amount of haemoglobin in blood. The Hb is vital protein present in red blood cells that carry oxygen from the lungs to different tissues of the body and carbon dioxide back from tissues to the lungs. A low level of Hb indicates a condition called anaemia which can be due to different causes.

TC blood test measures the total number of white blood cells also called leucocytes in blood. Their function is to defend the body against various infections.

DC blood test measures the percentage of various components of white blood cells in blood. These components are neutrophils, eosinophils, basophils, lymphocytes and monocytes.

Erythrocyte Sedimentation Rate tests measures how fast erythrocytes (red blood cells) settle down in a test tube containing blood sample. If ESR is high it may indicate inflammation which can be due to infection, injury, chronic disease or some immune disorder.

Platelet count measures platelets in blood. Platelets are also called thrombocytes.The function of platelets is stop bleeding by forming blood clot.

We, Svasthya ZNJ lab, are the right choice for good service and precise result.

Call us for sample collections – 7606004135

Book through our website – www.svasthyaznj.com

#svasthyaznj #svasthyaznjlabs #neurology

[zoolgytalks]

SICKLE CELL ANEMIA

INTRODUCTION TO SICKLE CELL ANEMIA  Sickle Cell Anemia falls under the broader category of sickle cell disease (SCD), which encompasses a group of inherited red blood cell disorders. Hemoglobin is a protein responsible for carrying oxygen in red blood cells. In Sickle Cell Anemia, a single amino acid change in the hemoglobin beta chain leads to the formation of hemoglobin S (HbS). Under…

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[iasguidance]

Awareness Campaign Launched for Sickle-cell disease (SCD)

Context: The Tribal Minister of India launched a training session for an awareness campaign that’s part of the government’s mission to make India free of Sickle-cell disease (SCD) by 2047. It is a group of inherited red blood cell disorders that are caused by a mutation in the hemoglobin gene. This mutation leads to the production of abnormal hemoglobin, known as hemoglobin S (HbS), which causes…

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#Biology & Biotechnology #GS Paper 2 #GS Paper 3 #Health #Prelims Nuggets

[health-today-info]

Managing Diabetes Through Regular HbA1C Testing

Living with diabetes requires a proactive and vigilant approach to managing blood sugar levels. While regular glucose monitoring plays a crucial role in day-to-day diabetes management, there's another test that offers a broader perspective on your long-term glycemic control – the Glycosylated Hb (HbA1C) test. In this article, we'll delve into the significance of regular HbA1C testing and how it empowers individuals with diabetes to take charge of their health.

What is HbA1C?

HbA1C, often referred to simply as A1C, is a measure of the average blood sugar levels over the past two to three months. Unlike traditional glucose tests that provide a snapshot of your current blood sugar, HbA1C test reflects your overall glycemic control during that extended time frame. The test measures the percentage of hemoglobin in your red blood cells that is coated with glucose. The higher your blood sugar levels have been, the more glucose will be attached to your hemoglobin.

The Importance of Regular Testing

Long-Term Control Assessment: Monitoring your day-to-day blood sugar levels is essential, but they can fluctuate due to various factors like diet, activity, stress, and illness. HbA1C provides a more comprehensive view of your blood sugar control over time, helping you and your healthcare team assess the effectiveness of your treatment plan.

Early Detection and Intervention: Regular HbA1C testing allows for early detection of potential problems. If your HbA1C levels are consistently elevated, it could indicate that your current treatment plan needs adjustment before serious complications arise.

Goal Setting and Monitoring: Diabetes management often involves setting target HbA1C levels as part of an individualized treatment plan. Regular testing helps you track your progress toward these goals and make necessary changes to achieve optimal glycemic control.

Personalized Treatment Plans: Your healthcare provider can use HbA1C results to tailor your diabetes management strategy. If your levels are higher than desired, they can recommend lifestyle changes, medication adjustments, or other interventions to bring your blood sugar under control.

Reducing Complications: Well-managed diabetes reduces the risk of complications such as nerve damage, kidney disease, vision problems, and cardiovascular issues. By maintaining healthy HbA1C levels, you're taking significant steps to prevent these complications.

Frequency of Testing

The frequency of HbA1C testing varies based on individual circumstances. Generally, people with well-controlled diabetes may have the blood tests every six months, while those with less controlled diabetes or treatment changes might require more frequent testing.

Preparing for the Test

HbA1C testing doesn't require fasting, making it convenient for individuals. However, it's important to maintain your regular routine and diet leading up to the test to ensure accurate results.

Conclusion

Regular HbA1C testing is a fundamental tool in the management of diabetes. It empowers individuals to gain insights into their long-term blood sugar control, make informed decisions about their treatment plans, and reduce the risk of complications associated with diabetes. By working closely with healthcare professionals and utilising the valuable information provided by the HbA1C test, individuals can lead healthier and more fulfilling lives despite the challenges of diabetes. Remember, knowledge is power, and regular testing is a key to unlocking that power in your diabetes journey.

#HbA1c test #sugar test #diabetes #HbA1c test levels #diabetes management