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#eosinophilic gastroenteritis
eosinophil-hate-blog 9 months
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Here's the study if anyone is interested:
Dellon ES, Gonsalves N, Abonia JP, et al. International Consensus Recommendations for Eosinophilic Gastrointestinal Disease Nomenclature. Clin Gastroenterol Hepatol. 2022;20(11):2474-2484.e3. doi:10.1016/j.cgh.2022.02.017
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longhaulerbear 1 year
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Although gluten is believed to be a potential trigger for symptoms, other components of wheat may also be triggers, including fructans, alpha-amylase trypsin inhibitors, and wheat germ agglutinins. Several primary gastrointestinal disorders are associated with an increase in inflammatory cells including eosinophils.
Diet seems to be an important driver of disease pathogenesis in eosinophilic gastroenteritis, with elimination and elemental diets showing promise in management, with further robust trials required. Small intestinal bacterial overgrowth is an example of microbial dysbiosis, with renewed interest in diet being postulated to cause an adaptive change of the microbes colonizing the small intestine. However, the diagnosis of small intestinal bacterial overgrowth is limited by a lack of sensitive and specific tests, with significant knowledge gaps in relation to therapeutic measures to manage and cure small intestinal bacterial overgrowth. Currently, antimicrobials are the established management option. There have been significant clinical advances in dietary interventions related to the small bowel, but this area is currently a novel and advancing field for both patients and clinicians.
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chicago-geniza 1 year
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It's Shitting Blood Thursday 馃帀
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teachingrounds 2 years
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What is FPIES?
Food Protein-Induced Enterocolitis Syndrome is a rare condition in which an infant presents with acute gastrointestinal symptoms or even a sepsis-like picture within 1-4 hours of eating the culprit food, usually milk, soy, oatmeal, or rice. The reaction is T-cell mediated, so there aren't hives or respiratory symptoms as in IgE-mediated allergic reactions. Treat with oral rehydration, IV fluids, Zofran, +/- steroids. Symptoms resolve <24 hours, otherwise allergic eosinophilic gastroenteritis is more likely. Usually diagnosed <12 months of age. 80% are fed extensively hydrolyzed formula (Alimentum, Nutramigen, Pregestimil, Expert Care), while 20% need elemental formula (Neocate, EleCare, PurAmino, Alfamino). The child typically outgrows the intolerance by 3-5 years.
Pro-Tip: October 14 is Global FPIES Day!
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drpedi07 8 months
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Eosinophilic Gastrointestinal Disease
According to the localization of the gastrointestinal tract, primary eosinophilic gastrointestinal diseases include five variants such as esophagitis, gastritis, gastroenteritis, enteritis, and colitis.
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desmoinesnewsdesk 10 months
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Eosinophilic Gastroenteritis Market Report 2032: Epidemiology Data, Pipeline Therapies, Latest Drug Approvals by DelveInsight | Novartis, Allakos, AstraZeneca, Pfizer, Regeneron, Celgene
http://dlvr.it/Sr1ZHQ
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columbianewsupdates 10 months
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Eosinophilic Gastroenteritis Market Report 2032: Epidemiology Data, Pipeline Therapies, Latest Drug Approvals by DelveInsight | Novartis, Allakos, AstraZeneca, Pfizer, Regeneron, Celgene
http://dlvr.it/Sr1Wt1
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newsheadlinesnow 10 months
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Eosinophilic Gastroenteritis Market Report 2032: Epidemiology Data, Pipeline Therapies, Latest Drug Approvals by DelveInsight | Novartis, Allakos, AstraZeneca, Pfizer, Regeneron, Celgene
http://dlvr.it/Sr1WJT
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thesunshinereporter 10 months
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Eosinophilic Gastroenteritis Market Report 2032: Epidemiology Data, Pipeline Therapies, Latest Drug Approvals by DelveInsight | Novartis, Allakos, AstraZeneca, Pfizer, Regeneron, Celgene
http://dlvr.it/Sr1V84
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thealphareporter 10 months
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Eosinophilic Gastroenteritis Market Report 2032: Epidemiology Data, Pipeline Therapies, Latest Drug Approvals by DelveInsight | Novartis, Allakos, AstraZeneca, Pfizer, Regeneron, Celgene
http://dlvr.it/Sr1TFv
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technewspoint 10 months
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Eosinophilic Gastroenteritis Market Report 2032: Epidemiology Data, Pipeline Therapies, Latest Drug Approvals by DelveInsight | Novartis, Allakos, AstraZeneca, Pfizer, Regeneron, Celgene
http://dlvr.it/Sr1SCD
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eosinophil-hate-blog 2 years
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Eosinophil Awareness Week is May 15 - 21, 2022!
This week is Eosinophil Awareness Week! The goal is to raise awareness for eosinophilic disorders, and the impact these rare illnesses have on the people afflicted with them.
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shwoo 1 year
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I had a gastroenterologist appointment earlier this week. I had to keep saying that I thought the problem was in my small intestines, and that I didn't want another gastroscopy since they didn't find anything the last two times. The gastroenterologist also said that there was a new treatment for eosinophilic esophagitis that I could try, but I'd need a fresh diagnosis, which would also involve a gastroscopy. The current treatment is working fine, though. And it's helping my other problems as well.
She eventually said that she'd have to refer me to the only gastroenterologist in the city that looks at the small intestine, because she doesn't do that procedure. I didn't even know there was a small intestine-oscopy that didn't involve surgery, so that's kind of a relief. And by her, she meant my GP, because specialist referrals only last for three months. I'm not sure if I'm meant to wait until someone contacts me, but I think I'll call the GP to find out what's happening once I feel up to it.
The gastroenterologist kept saying that eosinophilic gastroenteritis was really rare, and yes, but if it was something that wasn't rare, it probably would've been found by now. Anyway, it would be a good idea to actually look at the place where the pain is coming from, regardless of whether the exact problem is what I think.
I just wish I knew which specialist to talk to about my symptoms who wouldn't start talking like the symptoms were something totally different that they could investigate or treat. I understand the urge, but it's not actually helping at all. Everything outside a tiny range of foods that I don't really know the bounds of makes my immune system go on the attack, and it's not an allergy. That's the problem here.
Right now I'm hoping that having a look at my small intestines will at least narrow things down a bit. Unfortunately, there's a lot of ground to cover there.
...Wow, I have way too many tabs open. I'm going to try to queue some of the posts I opened with the intention of reblogging and then forgot about it.
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coldspellwizard 3 years
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Hey digestive system, maybe you could like function normally instead of severe cramping and symptoms+
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mcatmemoranda 5 years
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Watching OnlineMedEd Esophagitis video.
If EGD shows eosinophils, give PPI. GERD can cause eosinophilic esophagitis. So treat GERD so it won't cause eosinophilic esophagitis. If treatment fails, use oral aerosolized steroids. So there are 2 scenarios:
Pt with GERD symptoms gets a PPI for 6 weeks, but that doesn't help, so he gets an endoscopy. If the biopsy from endoscopy shows 15 or more eosinophils per high power field, then he has eosinophilic esophagitis, which is treated with oral aerosolized steroids.
The other scenario is a person who comes in with symptoms of GERD, who gets biopsied, then gets put on a PPI.
Honestly, he didn't explain the two scenarios well.
But I guess the point he was trying to make is that if the pt has esophagitis symptoms, first line treatment is PPI. Then if that fails, you do EGD. Then if the biopsy you got from EGD shows 15 eosinophils/hpf, it's eosinophilic esophagitis, which you treat with aerosolized steroids. So first line treatment for eosinophilic esophagitis is a PPI. If PPI fails, then it's aerosolized steroids. The PPI is given first because GERD can cause eosinophilic esophagitis.
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itskatrinamarie 6 years
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Just a reminder! People who have invisible illnesses are still ill whether you see it or not and are just as valid as those with visible illnesses.
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