#ethylene glycol
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Tragic Lessons: The Elixir Sulfanilamide Incident and the Birth of Drug Safety Regulation
In 1937, the US-based Massengil pharmaceutical company's chemists developed a new sulfonamide oral preparation named "Elixir Sulfanilamide." At that time, there was no requirement for safety review before launching new drugs. Consequently, this untested drug went on sale in September of that year. In October, the American Medical Association received reports of fatalities caused by the medication.
In November, the US Food and Drug Administration (FDA) intervened, recalling the drug. The investigation found that "ethylene glycol," used as a solvent in the drug, was the main culprit of poisoning. Ethylene glycol is highly toxic to mammals, with a minimum lethal dose (LD₅₀) of 786 mg/kg in humans. This issue, easily detectable through a simple animal experiment, resulted in over 100 deaths that fall, with 30% being children.
The following year, under immense public pressure, the US Congress passed the landmark "Federal Food, Drug, and Cosmetic Act" (FFDCA), mandating safety reviews for all new drugs before market approval and granting the FDA regulatory oversight authority.
#fda#us fda#drug safety#drug#ethylene glycol#chemblr#stemblr#science#molecule#chemistry#kingdraw#incidence#toxicity
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Ethylene glycol (see figure 19.2) and propylene glycol are synthesised from ethylene (ethene) and propylene (propene) respectively, hence their common names as shown below.
"Chemistry" 2e - Blackman, A., Bottle, S., Schmid, S., Mocerino, M., Wille, U.
#book quotes#chemistry#nonfiction#textbook#ethylene glycol#propylene glycol#ethylene#ethene#propylene#propene#synthesis#polarity#ethane#propane
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Some solutes are liquids, like the ethylene glycol dissolved in water to stop it from freezing in a car's radiator.
"Chemistry" 2e - Blackman, A., Bottle, S., Schmid, S., Mocerino, M., Wille, U.
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my fingerprints on the inside of the glass,
trapped within mountains of fake snow and
gravity, a curiosity on a shelf.
shake me, hurt me, watch me fall apart,
watch me rain until i no longer move / until
i bore you with my silence / my refusal to die .
pretty pictures painted / with blood on the
inside of the glass. warped words & missed
messages for a god whose place you have taken.
let me out, let me watch, let me bury myself
in white plastic & drown in anti freeze, let me
gather dust, safe from time, alone in the dark.
#alex writes#spilled ink#original poetry#y'know i was very disappointed to find out the snow in snow globe is literally just plastic#some water‚ some ethylene glycol and some glycerine and there you have it#boring but still a good metaphor
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A Turned Key
Gears move slow after being wound,
to play a lovely little sound,
starwheel running perfectly against comb,
a melody resonating close to home.
Snowfalls with a quick shake,
over a sleepy town that doesn't wake,
surrounding a large fir,
adorned with ornaments that don't stir.
Only a red train spins round,
ducking in and out of tunnels underground,
but when the music fades away,
the train also ceases to make its way.
#poem#writerscreedchallenge#snowglobes#the liquid inside can be water in the#plastic ones#but the glass ones can have ethylene glycol#antifreeze so the water inside wont freeze in the cold
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chemistry is so funny because the same basic elements make up everything
like you can have two substances that are wildly different but made up of the same things, so their names or chemical structures will look really similar, except one will be essential to life and the other one will be poison
#personal#prompted by me realizing that polyethylene glycol and ethylene glycol sound really similar#but the former is miralax and the latter is antifreeze#also shout out to my one patient who was worried about what we used in our disinfectant wipes#and i was like oh this one is just straight up ethyl alcohol#and she was like UH ISN'T THAT ANTIFREEZE? and i'm like. no it is not.#ethyl alcohol is literally the stuff you drink. i'm basically holding moonshine right now#but i can see your concern lmao
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Buy Coolant Mono Ethylene Glycol at Fair Prices
Discover the finest coolant mono ethylene glycol at Chemical Iran's online store - your one-stop destination for top-quality products, hassle-free shipping, and unbeatable prices. Shop now!
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Mono Ethylene Glycol Price, Trend, Prices, Demand & Market Analysis | ChemAnalyst
The Mono Ethylene Glycol (MEG) market has experienced dynamic fluctuations in prices, influenced by a myriad of factors that shape the global petrochemical landscape. MEG, a crucial raw material in the production of polyester fibers, resins, and antifreeze solutions, is integral to various industries, including textiles, automotive, and packaging. The market's pricing dynamics are intricately tied to the supply-demand balance, feedstock costs, and geopolitical events.
One of the primary drivers of MEG prices is the supply-demand equilibrium. As a commodity with diverse applications, any shift in demand or supply can significantly impact its market value. The increasing demand for polyester fibers, driven by the textile and apparel industry's growth, has been a pivotal factor in sustaining MEG prices. Additionally, MEG's role in the production of PET (polyethylene terephthalate) resins for packaging applications further contributes to its demand dynamics. Market participants closely monitor these demand-side factors to anticipate price movements and formulate strategic decisions.
The cost of feedstock, typically naphtha or ethylene, plays a pivotal role in determining MEG prices. Fluctuations in crude oil prices directly influence the cost of feedstock, thereby affecting the production cost of MEG. As a result, geopolitical events, OPEC decisions, and global economic conditions can exert profound effects on MEG market prices. Manufacturers and stakeholders closely track these external factors to assess potential risks and opportunities in the market, as any significant shift in feedstock costs can reverberate throughout the supply chain.
Furthermore, technological advancements and innovations in MEG production processes contribute to market dynamics. Continuous efforts to enhance production efficiency and reduce manufacturing costs influence the overall pricing structure. Manufacturers adopting more sustainable and environmentally friendly production methods may face initial capital investments but can potentially benefit from cost savings in the long run, thereby impacting the competitive landscape and market prices.
Get Real Time Prices of Mono Ethylene Glycol (MEG): https://www.chemanalyst.com/Pricing-data/mono-ethylene-glycol-4
Global economic conditions also exert a significant influence on the MEG market. Economic downturns can lead to decreased consumer spending on textiles, automotive, and other MEG-dependent industries, affecting overall demand and subsequently impacting prices. Conversely, economic growth and increased industrial activities can drive up demand for MEG, putting upward pressure on prices. The interconnectedness of the global economy necessitates a comprehensive analysis of economic indicators for accurate market price predictions.
Market players closely monitor regional dynamics as well, as different regions exhibit unique demand-supply balances and economic conditions. Asia-Pacific, with its burgeoning industrial sectors and robust textile industry, often emerges as a key driver of MEG demand. Meanwhile, geopolitical tensions, trade agreements, and regulatory changes can introduce uncertainties that influence regional market prices. Stakeholders navigating the MEG market must remain attuned to these regional nuances to formulate effective strategies in response to changing price dynamics.
The Mono Ethylene Glycol (MEG) market is a complex and dynamic ecosystem influenced by a multitude of factors. From supply-demand dynamics and feedstock costs to technological innovations and global economic conditions, market participants must navigate a multifaceted landscape. Staying informed about these variables is crucial for stakeholders seeking to make informed decisions in a market where prices are not only reflective of immediate demand but also shaped by broader economic and geopolitical forces. As the MEG market continues to evolve, strategic foresight and adaptability will be essential for businesses to thrive in this intricate and interconnected industry.
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https://travelwithme.social/read-blog/22007
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2027 Ethylene Glycol Capacity & Expenditure
Get insights into the Ethylene Glycol industry's growth with forecasts for plant capacity and spending.
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Ethylene Glycol market size was valued at USD 36.93 billion in 2022, which is expected to grow to USD 58.77 billion in 2030 with a CAGR of 5.98% during the forecast period between 2023 and 2030. Ethylene Glycol is an organic compound that finds application in various industrial segments.
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#institutional racism#indian pharmaceutical company#exported cough syrup#ethylene glycol#glass fragments
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Ethylene Glycol Monobutyl Ether
Cars containing vinyl chloride, butyl acrylate, ethylhexyl acrylate, isobutylene and ethylene glycol monobutyl ether are known to have been released to the air, surface soils and surface waters.
#Ethylene Glycol Monobutyl Ether#Treason#Truth#AmericaFirst#BorderCrisis#FreedomFighter#Freedom#AmericanConstitution#BillOfRights#FreedomOfSpeech#TruthSocial#WakeUpAmerica#ACLU#Constitution#firstAmendment#SecondAmendment#FourthAmendment#Fraud#Mommy?Daddy?#Satire#Hypocrite#justice#Equal justice#equal justice#ecological disaster#Ohio#Palestine Ohio#Train Wreck#Chemical Disaster#Spy Balloons
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