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allthebrazilianpolitics · 4 months

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Institute submits Brazil’s first chikungunya vaccine for approval amid rising cases

The Butantan Institute, linked to the state of São Paulo’s Health Department, on December 12 submitted a request for the use of Brazil’s first chikungunya vaccine to Anvisa, the country’s national health monitoring agency.

The vaccine, developed in partnership with the Franco-Austrian pharmaceutical company Valneva, has proven to be safe and effective in two phase 3 clinical trials, with the second trial coordinated by the Butantan Institute involving Brazilian volunteer teenagers.

The study showed that the vaccine induced the production of neutralizing antibodies in 98.8% of the volunteers. According to the Ministry of Health, until early September, Brazil had 82 deaths from chikungunya and 143,000 cases in 2023.

José Moreira, medical director of Clinical Development at Butantan, said that chikungunya is a quite peculiar disease, as 30% to 35% of infected people develop chronic joint pain. This situation can negatively impact people’s quality of life.

#brazil #brazilian politics #politics #science #vaccination #medicine #chikungunya #mod nise da silveira #image description in alt

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bpod-bpod · 10 months

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Change the Channel

Blocking the budding of viruses – when they wrap themselves in the host cell membrane and move off to spread the infection – could be a good strategy to stop them in their tracks. Researchers interested in alphaviruses – a type that includes chikungunya and Sindbis viruses – examined the role of a protein called 6K in virus assembly and spreading. They found that it functions as a channel to let molecules pass through membranes, like has been seen in proteins of HIV and influenza. This ion channel activity was needed for the formation of vacuoles in the cell, which promote the transport of proteins to the cell lining where they are incorporated into new virus particles (these proteins in red spread throughout the membrane, left, compared to clumping in the absence of 6K, right). Interfering with 6K action could be a new way to treat infection, and nip budding in the bud.

Written by Anthony Lewis

Image from work by Zeinab Elmasri and colleagues

Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, USA

Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in PLOS Pathogens, October 2022

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#science #biomedicine #chikungunya #sindbis #influenza #hiv #ion channel #viruses #vacuoles #immunofluorescence

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pathologylab · 16 days

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The detection of vector-borne diseases has been significantly facilitated by #G2M's Para2-Q Real-Time #PCR Kit. This kit utilizes cutting-edge real-time PCR technology to qualitatively detect RNA from #Dengue, Chikungunya, Zika, West Nile #Virus, Yellow Fever, and Japanese encephalitis in clinical samples.

Our product is meticulously designed for real-time system multiplex two-tube #assays, incorporating specialized primers and probes that target the sequences of these viruses. Additionally, it includes an internal control to ensure accuracy and reliability.

Visit our website for more information: https://www.genes2me.com/ivd-real-time-pcr-test-kits/vector-borne-transmission-detection-kit

For more details, Call us at +91-8800821778 or drop us an email at [email protected]

#RTPCR #Para2 #DNA #Genes2Me #kit #vector #testing #diagnostic #realtime #Chikungunya #virus #detection #zika #yellowfever #rna #diagnosis #ivd

#g2m #genes2me #rt pcr #pcr #ivd #diagnosis #testing #kits #zika #dectection #diagnostic #chikungunya #virus #yellow fever

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acapulcopress · 24 days

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Ante proximidad de lluvias, exhorta Salud a guerrerenses a prevenir el dengue

CHILPANCINGO * Abril 2, 2024. ) Salud Guerrero

Ante la proximidad de la temporada de lluvias, la Secretaría de Salud Guerrero (SSG), hace el llamado anticipado a los guerrerenses a participar activamente desde sus hogares en las acciones preventivas para contribuir a que no se incremente el número de casos de dengue en el estado. La dependencia estatal informó que como cada año, durante la temporada de lluvias que da inicio en el mes de mayo, aumenta la presencia del mosco Aedes aegypti, principal vector transmisor del dengue, zika y chikungunya, con lo cual aumenta la cifra de enfermos por estos padecimientos virales, por lo cual la dependencia estatal, recomienda mantener sus depósitos de agua limpios y tapados para evitar criaderos de moscos, también mantener su entorno limpio, sin cacharros, llantas o cualquier objeto que pueda cumular agua para que no se conviertan en criaderos. La Secretaría de Salud, puntualizó que en Guerrero se han mantenido las acciones preventivas, para contrarrestar este problema de salud pública, sin embargo, la parte prioritaria de la prevención recae en cada habitante desde sus hogares, se informó que él combate al dengue en el estado se ha mantenido desde que dio inicio el año y que continuará de manera permanente con acciones de control larvario y nebulización en zonas prioritarias del estado.

Detalló que para esta labor se ha contratado a 530 elementos eventuales, responsables de realizar la difusión de recomendaciones y para llevar a cabo labores de descacharre y abatización. Hasta la fecha, la nebulización espacial se ha realizado en 91 mil 853 hectáreas, además de que se ha realizado rociado rápido residual en 20 mil 842 casas, con casos de dengue. A la par se han cubierto 15 mil 939 hectáreas con nebulización con máquinas térmicas y para el control larvario en depósitos de agua, el personal ha aplicado abate en 492 mil 673 viviendas. Hasta este 31 de marzo se tiene un registro de 2 mil 644 casos, concentrados mayormente en Acapulco, Iguala, Chilpancingo, Zumpango y Zihuatanejo. ) acapulcopress.com Read the full article

#Chikungunya #Dengue #MoscoAedesaegypti #SecretaríadeSaludGuerrero(SSG)#Zika

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estiloconsultorias · 1 month

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Saúde: Identificação de Covid-19, Dengue, Zika e Chikungunya: Como Diferenciar os Sintomas?

Com o aumento alarmante dos casos de dengue no Brasil, surge uma preocupação adicional para a população: como distinguir os sintomas da dengue dos sintomas de outras doenças virais, como Covid-19, Zika e Chikungunya? Embora essas doenças possam compartilhar sintomas semelhantes, pequenos sinais podem ajudar a especificar cada uma delas, permitindo um diagnóstico mais preciso e um tratamento…

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#Chikungunya #covid-19 #dengue #destaque #saúde #zika

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oaresearchpaper · 2 months

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#Dengue #Chikungunya #Co-infection #IgM antibody capture ELISA

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centraldenoticiasmx · 2 months

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Mantener acciones de eliminación de criaderos permite prevenir dengue, zika y chikungunya: Servicios de Salud

🖊️#Salud | Mantener acciones de eliminación de criaderos permite prevenir dengue, zika y chikungunya: Servicios de Salud +INFO:

Servicios de Salud de Morelos (SSM) puntualizó que se debe reforzar la acción de lavar superficies y objetos que acumulen agua en jardines, azoteas y patios del hogar para eliminar criaderos de mosquitos transmisores de dengue, zika y chikungunya. Eduardo Sesma Medrano, coordinador de Vigilancia Epidemiológica de SSM, indicó que también es necesario limpiar las cubetas, tanques, botes, piletas,…

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#Chikungunya #Dengue #sika

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biterepel · 2 months

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The Fight Against Wild & GM (Genetically Modified) Mosquitoes

Biotech company releases 500M genetically modified mosquitoes into the wild to control the mosquito population. Scientists hope these bugs can help stop the spread of some dangerous viruses over time.

With over 200 species of wild mosquitoes buzzing around America and the U.S. territories. One type that’s common in many parts of the country is the Aedes Aegypti. It can spread diseases like Malaria, Dengue, Zika, Yellow Fever, Mayaro, West Nile and Chikungunya through its bite.

Now if that wasn’t bad enough, scientists have proven that mosquitoes are spreading Buruli Ulcer (Mycobacterium ulcerans infection). Buruli (a flesh eating disease) is a chronic debilitating disease that affects the skin and sometimes bone and can lead to permanent disfigurement and long-term disability.

Mosquitoes Are a Growing Public Health Threat, Reversing Years of Progress. Climate change and the rapid evolution of the insect have helped drive up malaria deaths and brought dengue and other mosquito-borne viruses to places that never had to worry about them — The New York Times

Mosquito activity can vary depending on the specific area and the time of year. In general, mosquitoes are more active during the warmer months, typically from late spring through early fall. However, the exact timing and abundance of mosquitoes can be influenced by several factors, including temperature, precipitation, and local environmental conditions.

To Minimize mosquito encounters and reduce the risk of mosquito-borne diseases, it’s a good idea to take preventive measures such as using the right kind of mosquito repellent, wearing long-sleeved clothing helps, and eliminating sources of standing water around your property, as standing water is where mosquitoes lay their eggs. Additionally, local health authorities and mosquito control agencies often monitor and manage mosquito populations to help mitigate the spread of diseases, but unfortunately the products aren’t working with the rapid expansion of new mosquito and vector-borne species, as they are Immune to Deet and or Citronella.

To Combat mosquitoes, we created BiteRepel and have produced three versions of BiteRepel:

BiteRepel Outdoors - Indoor / Outdoor Home Barrier

BiteRepel Topical - Personal Protection Indoor/ Outdoor

BiteRepel Pets & Livestock – Flea & Tick Prevention.

See FAQ page for more details & use instructions

BiteRepel Website

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n7india · 2 months

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चिकनगुनिया के कारण हृदय और गुर्दे की बीमारी से मृत्यु का खतरा बढ़ जाता है : रिसर्च

London: द लेसेंट इंफेक्शियस डिजीज में प्रकाशित नए शोध में खुलासा हुआ है कि चिकनगुनिया वायरस (सीएचआईकेवी) से संक्रमित लोगों में संक्रमण के तीन महीने बाद तक हृदय और किडनी की जटिलताओं से मौत का खतरा बढ़ जाता है। चिकनगुनिया एक वायरल बीमारी है, जो मच्छरों से इंसानों में फैलती है। आमतौर पर, यह वायरस एडीज एजिप्टी और एडीज एल्बोपिक्टस मच्छरों से फैलता है, जिन्हें आमतौर पर येलो फीवर और टाइगर मच्छर के रूप…

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#chikungunya

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cientirinhas · 2 months

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#402 #biologia #sociedade #carnaval #dengue #zika #chikungunya #cantada #fantasias #verão #aedes aegypti

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rentokilpci · 3 months

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Mosquito menace on the rise? Shield yourself from the threat of mosquito-borne diseases. Call Rentokil PCI and ensure your space stays mosquito-free. Don't let these tiny terrors take control!

#rentokilpci #mosquito #pestcontrol #chikungunya #dengue

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allthebrazilianpolitics · 2 months

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Dengue, Zika, and Chikungunya Expected to Deduct $ 3 Billion from Brazil's Economy in 2024

Fiemg survey says health expenditures due to these diseases will amount to $ 1 billion

Dengue, Zika, and Chikungunya will deduct R$ 15.1 billion ($ 3 billion) from the Brazilian economy in 2024. The projection was presented by Fiemg (Federation of Industries of the State of Minas Gerais).

In addition to affecting GDP (Gross Domestic Product), the three arboviruses will cost health care R$ 5.2 billion ($ 1 billion) in tests, consultations, and medications.

According to the study, the diseases may prevent the creation or cut more than 214,000 jobs.

#brazil #brazilian politics #politics #economy #dengue #zika #chikungunya #mod nise da silveira #image description in alt

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bpod-bpod · 2 years

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Mosquito Monitoring

As the global temperatures rise, wildfires and extreme weather are not our only concerns. It’s predicted, for example, that mosquitoes and the diseases they carry will expand their geographical range to more temperate zones and higher altitudes. Not all species of mosquito carry human pathogens, but it would be helpful to know the whereabouts of the ones that do. Such surveillance on a global scale is a seemingly Herculean task, but it’s precisely the aim of the Global Mosquito Observation Dashboard. The good news is anyone with a smartphone can help. The initiative is citizen-scientist oriented, the idea being that people take photos of adult or larval mosquitoes (examples of the latter shown above) and submit them via mosquito-tracking apps associated with the scheme. Researchers can then identify the species and their locations (from the photos’ geotags) and get a heads-up as to where life-saving mosquito-control efforts should be focused.

Written by Ruth Williams

Image from the University of South Florida

Research by Ryan M. Carney et al, Department of Integrative Biology, University of South Florida (USF), FL, USA

Image copyright held by the original authors

Research published in Insects, July 2022

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#science #biomedicine #mosquitos #parasites #vectors #dengue #zika #malaria #chikungunya #west nile virus #citizen science #mosquito control #climate change

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multimediacreative · 3 months

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BEATING MOSQUITOES

BiograView was contacted by QIMR Berghofer Medical Research Institute with a media release of this Pacific alliance to combat mosquito-borne diseases. With all the hype around Covid-19 it is easy to forget other diseases still prevalent in the world. It is great to see so many international organisations working together to combat the still-present, mosquito-borne diseases. Twelve international…

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nuadox · 3 months

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Cases of chikungunya and zika fall in Brazil, but most risk clusters exhibit an upward trend

- By Julia Moióli , Agência FAPESP -

Analysis of occurrence and co-occurrence patterns shows the highest-risk clusters of chikungunya and zika in Brazil spreading from the Northeast to the Center-West and coastal areas of São Paulo state and Rio de Janeiro state in the Southeast between 2018 and 2021, and increasing again in the Northeast between 2019 and 2021.

In Brazil overall, spatial variations in the temporal trends for chikungunya and zika decreased 13% and 40% respectively, but 85% and 57% of the clusters in question displayed a rise in numbers of cases.

These findings are from an article published in Scientific Reports by researchers at the University of São Paulo’s School of Public Health (FSP-USP) and São Paulo state’s Center for Epidemiological Surveillance (CVE) who analyzed spatial-temporal patterns of occurrence and co-occurrence of the two arboviral diseases in all Brazilian municipalities as well as the environmental and socio-economic factors associated with them.

Considered neglected tropical diseases by the Pan American Health Organization (PAHO/WHO), chikungunya and zika are arboviral diseases caused by viruses of the families Togaviridae and Flaviviridae respectively, and transmitted by mosquitoes of the genus Aedes. Case numbers of both diseases have risen worldwide in the last decade and expanded geographically: chikungunya has been reported in 116 countries and zika in 92, according to the Centers for Disease Control and Prevention (CDC), the main health surveillance agency in the United States. Some 8 million people are estimated to have been infected worldwide, although the number may have reached 100 million in light of generalized underreporting of neglected tropical diseases.

The emergence and re-emergence of chikungunya and zika are facilitated by environmental factors such as urbanization, deforestation and climate change, including droughts and floods. “Identifying high-risk areas for the spread of these arboviruses is important both to control the vectors and to target public health measures correctly,” said Raquel Gardini Sanches Palasio, corresponding author of the article. She is affiliated with FSP-USP’s Department of Epidemiology, where she is a researcher in the Laboratory for Spatial Analysis in Health (LAES).

Working with her PhD thesis advisor, Francisco Chiaravalloti Neto, and other researchers at USP and CVE, Palasio analyzed more than 770,000 cases (608,388 of chikungunya and 162,992 of zika) diagnosed by laboratory test or clinical and epidemiological analysis; most were autochthonous (due to locally acquired infection). The analysis encompassed spatial, temporal and seasonal data, as well as temperature, rainfall and socio-economic factors.

The results showed that high-risk areas had higher temperatures and identified co-occurrence clusters in certain regions. “In the first few years of the period the high-risk clusters were in the Northeast. They then spread to the Center-West – zika in 2016 and chikungunya in 2018 – and to coastal areas in the Southeast – in 2018 and 2021 respectively – followed by resurgence in the Northeast,” Palasio said.

“Spatial variations in the temporal trends for chikungunya and zika decreased 13% and 40% respectively, but numbers of cases rose in 85% and 57% of the clusters concerned. Spatial variation clusters with a growing internal trend predominated in practically all states, with annual growth of 0.85%-96.56% for chikungunya and 2.77%-53.03% for zika.

“We also found that both diseases have occurred more frequently in summer and fall in Brazil since 2015. Chikungunya is associated with low rainfall, urbanization and social inequality, while zika correlates closely with high rainfall and lack of basic sanitation.”

Both are also more frequent in urban areas with less vegetation, she said, adding that socio-economic factors appear to correlate less with zika than with chikungunya.

Next steps

“Both diseases have the same vectors and are similar in some other ways, so theoretically they should occur in the same places. We didn’t observe perfect overlapping in space and time, however,” Palasio said.

A hypothesis raised by the researchers who conducted the study, which was funded by FAPESP, relates to socio-economic factors, environment and climate. The main source of data was the 2010 census, and next steps will include an update using fresh data from IBGE’s 2022 census.

“We also want to perform a spatial and temporal analysis using a broader dataset that takes socio-economic factors and climate [especially temperature and rainfall] into account together rather than separately,” Palasio said.

Another focus will be co-occurrence or overlapping of the two diseases. Future climate change models will be run under best-case and worst-case scenarios for greenhouse gas emissions.

The article “Zika, chikungunya and co-occurrence in Brazil: space-time clusters and associated environmental-socio-economic factors” is at: www.nature.com/articles/s41598-023-42930-4.

Image: Analysis of spatial variations in temporal trends for cases of chikungunya (A) and zika (B) in Brazil between 2015 and 2022. Credit: Scientific Reports.

This text was originally published by FAPESP Agency according to Creative Commons license CC-BY-NC-ND. Read the original here.

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