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#hiv & aids treatment
rudrjobdesk · 2 years
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HIV-AIDS cure underway: मिल गया HIV का इलाज! टीके के एक डोज से खत्म होगी बीमारी, इस देश के वैज्ञानिकों का दावा
HIV-AIDS cure underway: मिल गया HIV का इलाज! टीके के एक डोज से खत्म होगी बीमारी, इस देश के वैज्ञानिकों का दावा
Image Source : FILE PHOTO HIV-AIDS cure underway HIV-AIDS cure underway: एचआईवी एड्स दुनिया की सबसे खतरनाक बीमारियों में से एक है। बीते दशकों में दुनिया ने काफी तरक्की की। टेक्नोलॉजी में विश्व आगे बढ़ा, लेकिन एड्स जैसी लाइलाज बीमारी का हल नहीं खोजा जा सका। अब इजराइल से एक नई खबर आई है। दरअसल, कैंसर जैसी बीमारी के इलाज के बाद अब वैज्ञानिकों ने एचआईवी एड्स HIV/AIDS जैसी जानलेवा बीमारी का इलाज भी…
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reasonsforhope · 1 year
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"The “Düsseldorf Patient”, a man now aged 53, is just the third person worldwide to have been completely cured of HIV via stem cell transplantation.
As in the case of the other two patients, the so-called “Berlin Patient” and “London Patient,” the transplantation was undertaken to treat an acute blood disease, which had developed in addition to the HIV infection.
The Düsseldorf Patient received a stem cell transplant used to treat leukemia in 2013 and has shown persistent suppression of HIV-1 ever since, including during the last 4 years after the patient stopped taking anti-retroviral medication.
“I still remember very well the sentence from my family doctor: ‘don’t take it so hard,'” the Düsseldorf Patient, who had leukemia as well as HIV-1, said in a statement. “‘We will experience together that HIV can be cured!’ At the time, I dismissed the statement.”
Allogeneic hematopoietic stem cell transplantation (HSCT) is a procedure used to treat certain cancers, such as leukemia, by transferring immature blood cells from a donor to repopulate the bone marrow of the recipient.
Scientists now understand that individuals with two copies of the Δ32 mutation in the gene for the HIV-1 co-receptor CCR5; are resistant to HIV-1 infection. The two previous cases of both the London patient and the Berlin patient involved receiving a stem cell transplant from a donor with these unique mutations.
Björn-Erik Jensen, a specialist in infectious diseases at Düsseldorf University Hospital, lead the treatment and subsequent research, revealed today in a peer-reviewed study in Nature.
The patient was diagnosed as having acute myeloid leukemia and proceeded to undergo transplantation of stem cells from a female donor in 2013, followed by chemotherapy and infusions of donor lymphocytes.
After the transplantation, anti-retroviral therapy was continued, but HIV was undetectable in the patient’s blood cells. Anti-retroviral therapy was suspended in November 2018 with the patient’s informed consent, almost 6 years after the stem cell transplantation, to determine whether the virus persisted in the patient.
“I very much hope that these doctors will now get even more attention for their work,” said the patient. “I have now decided to give up some of my private life to support research fundraising. And of course, it will also stay very important for me to fight the stigmatization of HIV with my story.”
The authors conclude that although HSCT remains a high-risk procedure that is at present an option only for some people living with both HIV-1 and hematological cancers, these results may inform future strategies for achieving long-term remission of HIV-1."
-via Good News Network, 2/20/23
VERIFIED 10 YEARS ON, PROOF THAT HIV IS CURABLE
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blackmetalsnake · 5 months
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I just watched the last episode of the Fellow Travellers.
I'm dead. Thank you.
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sepulchritude · 2 years
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While I’m on a roll about contraceptives, condoms are the only form of birth control that also prevent the spread of STIs. Even if you are fully confident in the effectiveness of your birth control or you are someone who can’t get pregnant, condoms are your #1 best friend during any form of penetrative sex
If you’re someone who is at risk of contracting HIV, ask your doctor about PrEP! If you’ve had a recent exposure risk, then ask for PEP. These medications can prevent an HIV infection from taking hold, keeping you safely HIV-negative. I’m going to get serious here for a second when I say that HIV/AIDS used to be a death sentence, full stop. It has killed millions of people, and it does not care if you’re gay or straight or anything else. Thankfully we have treatments now, but the best thing you can do to protect yourself is to take steps to avoid being infected in the first place. That includes using condoms, making sure you and your partners get regular STI tests, and talking to your doctor about other forms of prevention like PrEP
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bokatan · 5 months
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for the botanical asks, magnolia, nasturtium, and angelica for reed (or whoever you prefer)?
[ botanical headcanons ]
magnolia: describe your muse's relationship with nature & the natural world.
Reed needs regular outside time to be a functional person. He feels very at home in nature and he’s at his best when he’s able to explore freely and be outside. He’s not picky about the biome but he likes just exploring, he’s the type that’s going to take 600 years to go anywhere because he’s busy flipping over logs and just admiring everything. He usually gets very agitated and reactive if he starts feeling like he’s being cooped up in any way, so most people he’s around often just learn to put up with his need to wander- he always comes back eventually.
nasturtium: describe your muse's relationship with their birthplace or homeland.
Reed doesn’t feel like he has any ties to his birthplace anymore due to the issues he’s had with his family; he doesn’t see New York as home anymore and doesn’t really have any interest in going back, aside from a little bit of morbid curiosity just to see how different it is in the postwar world. He’s uneasy with his relationship to his homeland too- he fell for the propaganda and rising nationalism at the time and joined the military because of it, but his opinion on the U.S. declined over time and he started to put a lot of energy into emotionally removing himself from what he’d done by the time he was discharged. Once he starts learning more about what the government & military had been doing behind closed doors, his opinions get even worse.
angelica: where does your muse draw inspiration in life? what motivates them?
His motives change a lot over time, but the main thing behind them is a desire to help make things better for everyone. That’s how he initially ends up in the BOS- he thinks the whole “keep advanced tech from being abused again” thing sounds great, and when he initially finds them he has no idea what super mutants, ghouls, synths, etc are so he’s not initially put off by that. That obviously changes later on and his motives shift into sabotaging the BOS with his goal being to get them out of the Commonwealth.
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worldaidsday · 3 years
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Highlight the role of nutrition for people living with HIV.
Food insecurity is associated with increased HIV transmission risk behaviours and decreased access to HIV treatment and care.
1. In 2019, around 38 million people globally had HIV — 1.7 million of them became infected with HIV within the past year.
2. Every week, more than 5,000 young women between 15–24 years become infected with HIV.
3. Adolescent girls and young women are increasingly infected by HIV — they make up 10 percent of the total HIV-positive population, but represent 25 percent of new HIV infections.
4.By ensuring that pregnant women living with HIV are diagnosed, started and retained on antiretroviral medicines during pregnancy, delivery and breastfeeding, the chances that they will pass on the virus to their newborn babies becomes less than 1 percent.
5.Out of 109 countries reporting to UNAIDS in 2017, 76 have laws that specifically criminalize HIV non-disclosure, exposure and transmission for prosecution based on general criminal laws. Four countries have reported that they criminalize mother-to-child transmission of HIV.
6. Whereas someone who acquired HIV in the pre-treatment era could expect to live only 12.5 years, a young person in industrialized countries who becomes infected today can expect to live a near normal lifespan.
7. In 2016, 2.6 million or 1 in 14 people living with HIV were affected by humanitarian emergencies.
8. In 2019, WFP reached around 400,000 people living with HIV and their families with in-kind, voucher or CBT transfers to protect their nutrition and food security, in 18 countries.
9. In 2019, WFP supported the national HIV response of 35 countries across the globe with capacity-strengthening activities
10. More than 25 million access antiretroviral therapy around the world by the end of 2019.
The World Food Programme (WFP) on the 10 things you may not know about HIV.
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haute-lifestyle-com · 2 years
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Ending HIV in America Premieres Wednesday, September 21, 2022 at 9pm ET/8C on PBS #janetwalker #hautelifestylecom #theentertainmentzonecom #hiv #aids #pbs
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xtruss · 1 month
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HIV Cure Nearer With Way To 'Shock And Kill' Latent Virus
— Published March 27, 2024 | Newsweek
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A Stock iIlustration Shows the Human Immunodeficiency Virus. Researchers May Have Found a Way to Remove Latent HIV From Cells, According to a New Study. IStock/Getty Images Plus
We might be a step closer to curing HIV, as researchers have developed a way to knock out a version of the virus lurking in the body.
Using something called an HIV-like particle (HLP)—which are dead HIV particles containing HIV proteins that trigger an immune response in a patient—may help treat the disease, scientists from the University of Western Ontario's Schulich School of Medicine and Dentistry and the U.K.'s University of Bristol reveal in a paper in the journal Emerging Microbes & Infections.
HLP was found to be 100 times more effective at treating the virus in people living with chronic HIV while on combined antiretroviral therapy (cART) than other candidate HIV cure therapeutics.
HIV, or human immunodeficiency virus, attacks the immune system, specifically targeting CD4 cells, which are crucial for helping the body fight infections and diseases. Without treatment, HIV can progress to the more advanced stage called AIDS, which can lead to death in only a few years.
More than 1.2 million people across the U.S. have HIV, with over 30,000 new cases diagnosed every year. There is no cure for HIV, but several treatments are available that can allow patients to live a long life.
HIV is treated primarily with cART, which is a combination of medications designed to suppress the replication of HIV in the body. This therapy works by targeting different stages of the HIV life cycle, preventing the virus from multiplying and reducing its levels in the bloodstream.
The goal of cART is to reduce the viral load (the amount of HIV in the blood) to undetectable levels, allowing the immune system to recover and preventing the progression of HIV to AIDS. However, cART doesn't completely eliminate the virus from the body, and the virus creates a "latent reservoir" where it hides within the cells of the body, lying dormant.
According to the new paper, HLP can help to purge cells of this latent HIV, making it a major step forward in treating and curing the infection.
"The development of this HIV cure was ten years in the making but with strong support from our collaborators in the US, Canada and Uganda, we have observed a striking ability of HLP to drive out the last remnants of HIV-1, which we hope will provide an affordable cure for all," said Eric Arts, the Canada research chair in HIV pathogenesis and viral control at the Schulich school, in a statement.
"To live HIV-free is a goal for the 39 million infected. It is also the priority of the UN and WHO to end the HIV pandemic by 2030," he added.
HLP, a deactivated version of HIV, contains various proteins that make it recognizable to the body as the virus, triggering an immune response. But it doesn't contain any of the structures that make the virus harmful and immunocompromising. HLP can therefore trigger the immune system to go hunting after HIV viruses remaining in the body, including the latent viruses hidden inside the immune cells. This allows the body to "shock and kill" the hidden viruses, the researchers said in the paper.
The researchers used blood samples from 32 patients with chronic HIV from the U.S., Uganda and Canada who had been on stable cART for a median of approximately 13 years. They found that HLP was able to specifically target just the immune cells containing a latent HIV reservoir, removing the virus from the cells.
"Over time, the virus grows more diverse within a single individual that is not on treatment which makes it more difficult to target," co-author Ryan Ho, a master's student at the Schulich school, said in the statement. "This formulation we've crafted covers the theoretical diversity so it can reach the HIV-1 in all those people living with HIV."
This is an extremely exciting discovery for HIV researchers, as it could be combined with cART and one day lead to the total elimination of HIV from the bodies of patients.
Minh Ha Ngo, the paper's lead author and a postdoctoral scholar at the Schulich school, said in the statement: "One concern expressed among people living with HIV for years is that continued use of cART could lead to the virus becoming unreachable and unable to be eliminated.
"The results of this study, by contrast, demonstrate that combining HLP with cART is still able to trigger the latent reservoir, even in chronic cases. If these dormant latent reservoirs can be awakened, then they can be eliminated from the body," Ngo said.
Additionally, HLP appeared to work on all variants of HIV from around the planet, indicating that it could be successful at treating even mutated versions of the virus.
"Owing to its high mutation rate, HIV exhibits remarkable genetic diversity, resulting in different viral subtypes, some of which predominate in particular regions of the globe," said Jamie Mann, a senior lecturer in vaccinology and immunotherapy at the University of Bristol's Veterinary School, in the statement.
"We were excited to see preliminary evidence that our HLP cure therapy reverses latency irrespective of the subtype of the individual's infection. Whilst this needs to be explored further, it hints at the global applicability of our approach," Mann said.
The researchers hope to test this HLP treatment across a larger cohort of people around the world to determine if it is an effective treatment strategy for those with both chronic and acute HIV.
— Jess Thomson is a Newsweek Science Reporter based in London UK 🇬🇧
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vitrogenbooster · 2 months
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discoverybody · 2 months
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AIDS: Progress in Treatment and Hope for the Future
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Thanks to major developments in the last few decades in the treatment of the condition, millions of AIDS patients worldwide now have hope. Thanks to dedicated research, more potent medications, and simpler access to healthcare, persons living with HIV may now enjoy longer, healthier lives. This essay looks at the incredible advancements in the fight against AIDS as well as the promising future.
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vasanthasworld · 2 months
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Hiv Or Aids Disease Symptoms And Treatment
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hfentertainment · 3 months
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theindianpharma · 4 months
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drmongalinic99 · 4 months
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HIV/AIDS Doctor In Noida call now - 8010977000
For effective treatment of HIV/AIDS in Noida, Dr. Yuvraj Monga stands as a leading expert. With compassion and expertise, Dr. Monga provides comprehensive care and the latest medical advancements in managing HIV/AIDS. As a trusted doctor, he focuses on personalized treatment plans, emphasizing both physical and emotional well-being. If you or a loved one seeks specialized care for HIV/AIDS, consider consulting with Dr. Yuvraj Monga in Noida for dedicated and compassionate support. Trust in his experience and commitment to improving the lives of individuals affected by HIV/AIDS in the region.
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worldaidsday · 3 years
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Globally, only half (52%) of children living with HIV are on life-saving treatment.
Adolescents and young people represent a growing share of people living with HIV worldwide; Most recent data indicate that only 25 per cent of adolescent girls and 17 per cent of adolescent boys aged 15-19 in Eastern and Southern Africa – the region most affected by HIV – have been tested for HIV in the past 12 months and received the result of the last test. The testing rates in West and Central Africa and South Asia are even lower. If current trends continue, hundreds of thousands more will become HIV-positive in the coming years, and without knowing their status, adolescents will miss out on life-saving treatment. Additionally, a large population of children infected with HIV perinatally over the last decade are growing into adolescence.
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