#telomeres

[reasonsforhope]

"Similar to the expeditions of a hundred or two hundred years ago, the Tara Pacific expedition lasted over two years. Its goal was to research the conditions for life and survival of corals. The ship crossed the entire Pacific Ocean, assembling the largest genetic inventory conducted in any marine system to date. The team's 70 scientists from eight countries took around 58,000 samples from the hundred coral reefs studied.

The first results of the analysis have now been published in Nature Communications. This largest-ever data set collection on coral reef ecosystems is freely available, and for years to come, will be the basis for elucidating the living conditions for corals and finding a way for them to survive climate change.

Important first results of the expedition show that global microbial biodiversity is much higher than previously thought. The impacts of the environment on evolutionary adaptation are species-specific, and important genes in corals are duplicated.

Global biodiversity ten times higher than assumed

Coral reefs are the most biologically diverse marine ecosystem on Earth. Although they cover only 0.16% of the world's oceans, they are home to about 35% of known marine species. Using a genetic marker-based data set, the researchers found that all of the globally estimated bacterial biodiversity is already contained in the microorganisms of coral reefs.

"We have been completely underestimating the global microbial biodiversity," says Christian Voolstra, professor of genetics of adaptation in aquatic systems at the University of Konstanz and scientific coordinator of the Tara Pacific expedition. He says the current estimate of biodiversity (approximately five million bacteria) is underestimated by about a factor of 10.

Impacts of the environment on evolutionary adaptation are species-specific

The 32 archipelagos studied serve as natural laboratories and provide a wide range of environmental conditions, allowing scientists to disentangle the relationships between environmental and genetic parameters across large spatial scales. This led to another important finding: The effects the environment has on evolutionary adaptation trajectories of corals are species-specific. To determine this, the researchers examined the telomeres, the ends of chromosomes that are the carriers of genetic information, for the first time.

In humans, the length of telomeres decreases during life; that is, with an increasing number of cell divisions, suggesting that biological age is closely linked to the length of telomeres. Researchers on the Tara Pacific expedition have now found that the telomeres in very stress-resistant corals are always the same length. "They apparently have a mechanism to preserve the lengths of their telomeres," Voolstra concludes...

Important genes are duplicated

Research data from the Tara Pacific expedition brought to light that the long life of some coral species may have yet another reason: the duplication of certain genes. Many important genes are present multiple times in the genome. The researchers were able to determine this through sequencing of coral genomes employing a new high-resolution technique.

This technique, called long-read sequencing, makes it possible to not only determine the set of genes present, but also to look at their order in the genome. According to Voolstra, the pervasive presence of gene duplication could be a possible explanation for why corals can live for thousands of years despite being exposed, for instance, to extreme UV radiation in shallow waters.

The entire data collection is freely accessible

All data sets are openly accessible and fully described with accompanying physical and chemical measurements to provide them as a scientific resource to all researchers.

"This is unique," Voolstra says. "It is the largest data set collection on coral reefs ever collected and it is completely open access." The aspiration is that this data collection will serve as a foundation and inventory to guide future study of coral reefs worldwide for many years."

-via Phys.org, June 26, 2023

#coral #coral reef #ocean #ocean conservation #biodiversity #microbiology #genetic diversity #genetic research #conservation #telomeres #genetics #climate change #evolution #ocean life #open access #good news #hope

[lifemod17]

hey guys, did you know that we go beyond the farthest reaches? like over there where the light bends and wraps beneath us?? because i know as you collapse into me, that this is in fact, the start of something. if you even care.

#sleep token #worshitposting #telomeres #this place will become your tomb

[infinifi]

Telomeres is so fuckin lovely I dislike anyone that dislikes it.

#sleep token #sleep token band #vessel sleep token #ii sleep token #iii sleep token #iv sleep token #telomeres

[polteergeistt]

Lil Telomeres solo for ya

As you can see I'm not pitch perfect at it yet, but I reckon I'm doing okay given how much time I put into it. So yeah. Give it a try. Because IV won't.

Shoutout to Méduse who is always here to support me in my musical endeavours.

#polteergeistt music #telomeres #sleep token cover #sleep token

[melit0n]

"And we go beyond the farthest reaches, where the light bends and wraps beneath us, and I know, as you collapse into me; this is the start of something."

#this one is absolutely DETRIMENTAL to my mental health #it gets worse each time I attempt to listen to it #if this monstrousity (lovingly) plays when I see them I don't think I'm actually making it out of the venue #one of you is gonna have to carry me in a ziplock bag because I'm just gonna be a puddle of tears #that's if I don't melt into the place itself #and that bloody breakdown #gets me everytime #I can literally see the cerulean wave crashing and dragging someone under #I can SEE the atoms collide I swear #this song means a lot to me if you guys can't tell #sleep token #st #telomeres #telomeres (song) #tpwbyt #this place will become your tomb #<- yeah it fucking will if that or Missing Limbs ever gets played live #Spotify #melitunes

[moonchild-in-blue]

Another over-share because I think you guys will appreciate it 💙🐳

I painted my notebook with some whales, because it was very boring plain black, and also Telomeres is beautiful and it's been on my mind lately.

The inside covers are not that great BUT I kinda like the sketchy look? idk.

#i almost posted without censoring my irl name oof #the runes read “Telomeres” and then “as above / so below” #i saw that post that compared the bottom of the ocean with the sky and that's all I've been thinking about lol #sleep token #telomeres #darya does art

[lookingforcactus]

The good news is that when humans finally figure out how to drastically slow biological aging by preserving or restoring the length of telomeres (x, x, x) or whatever else, rats will be one of the absolute first species to benefit

Because rats and mice almost certainly the first mammal that progress is tested on, in order to invent that kind of anti-aging technology in the first place

Sooner or later, we'll have pet rats with longer lives. Sooner or later!

#possibly a LOT later but STILL #pet rats #ratblr #fancy rats #rat #lab rats #telomeres #might fuck around and reblog this to my “reasons for hope” blog tbh #it might be an extremely niche reason for hope #but it's a very real reason for hope to me!! #lost too many pets in the last three years #mostly pet rats #cw animal death #genetics

[foundationsofdecay]

Sleep Token - Telomeres

(had to add ~7s to get it past copyright, deepest apologies)

#tried different sources and quality and metadata but this site hates me apparently </3 srry anon i really did try to get it to work w/o that #looks like on mobile you can scrub thru time stamps if that's where you're listening from. def if you have vanilla audio enabled on desktop #sleep token #telomeres #this place will become your tomb #audio

[sfsolstice]

and we go beyond the farthest reaches where the light bends and wraps beneath us and i know as you collapse into me this is the start of something

#sleep token #telomeres #tpwbyt #this place will become your tomb #Spotify #🎵 #solstice shares #this part of telomeres has been stuck in my head ALL DAY since the moment i woke up this morning #the universe is telling me something i just know it #also unrelated but i got a rejection from a lit mag just now so :')

[that-dutch-dude]

#telomeres #sleep token #this place will become your tomb #spotify

[realcleverscience]

Pretty fantastic stuff. I’m actually being cautiously optimistic till I see more research confirming this is real.

But basically, one of the causes of aging is when genes runs out its telemeres, which are protective caps for genes. this lack of telemore prevents them from splitting to form new cells. We’ve known that telemorase can help oversee telomeres but the researchers claim they’ve found something new: that certain types of cells can exchange telemores with other cells, thus rejuvinating them.

If scientists can figure out how to replicate this, and for all our cells, it could potentially rewind a major cause of aging.

In the study, in vitro, researchers initiated an immune response of T-lymphocytes against a microbe (foreign infection). Unexpectedly, they observed a telomere transfer reaction between two types of white blood cells, in ‘extracellular vesicles’ (small particles that facilitate intercellular communication). An antigen-presenting cell (APC), consisting either of B cells, dendritic cells, or macrophages, functioned as a ‘telomere donor’, to the T lymphocyte – the telomere recipient cell. Upon transfer of the telomeres, the recipient T cell became long-lived and possessed memory and stem cell attributes, enabling the T cell to protect a host against lethal infection in the long term.

#biology #science #aging #telomeres

[zenosanalytic]

So a few days ago I watched Annihilation(it's alright) on Netflix, and at one point Natalie Portman's character says to(I think?) her husband something like "Death is a flaw in your genes", and that's wrong.

Yes, telomere degradation DOES seem to play a role in gene replication errors, aging, and death, but that's not a mistake. Different species are effected by that degradation differently. Different species experience that degradation at different rates. This is how mayflies live for a day, and humans live for 60-100 years. Telemere degradation is selected for. Death is an evolutionary adaptation.

#Annihilation(Movie) #Genetics #Telomeres #Telomerase #Death #Evolution #zA Writes #zA Opinions #zA Reviews

[consult-sherlockholmes]

I wouldn't take you as the kind of person to care so much about aging. Surely you understand that insecurities related to aging are based purely on societal pressures to remain "beautiful" and able-bodied forever or else be perceived as "less valuable" for not fitting in with society's unrealistic standards

I do agree that the societal pressures concerning old age is stupid, however problems related to biological aging are indeed to be taken seriously. We all age and inevitably die, or bodies are not made to last forever, our genome accumulates more and more damage and mistakes, until it's so messed up that it starts to dysfunction, that cells become malignant. When our DNA is not working properly anymore, cell regeneration, structure and function will also be impaired, and if cells are impaired then organs on the next structural level are also impaired. Organs become less functional, the body's regenerative abilities decrease, damage that you could easily survive at a young age can easily kill you in old age. Not only your organs get less functional like lungs, heart, kidneys and also brain, damage over the years accumulating and not getting repaired anymore. Especially certain types of cells are much less likely to regenerate when older, especially neurological cells. Also your muscles atrophy, your strength decreases, pain gets worse, your bones become more brittle, all in all you can't do things you were able to do previously easily. And all of this continues and gets worse until a point when the body can't take it anymore and starts to fail, if it isn't already caused by external factors earlier. No one can live forever, our genetic code has a temporal limitation until it becomes dysfunctional, thanks to only a limited length of telomeres. All those factors are not just based on societal pressure to stay functional, they also affect you when there is no society to judge you, given that it's based on biology. You will become weaker, your organs will become less functional, no matter what society thinks about you.

So being concerned about all those future effects of aging are not at all just 'societal insecurities', they are real and reasonable.

However, aging is not only determined by genetics, but can majorly be influenced by how healthy you live, telomere lenght can be decreased by chronic stress, smoking, unhealthy diet, et cetera.

#roleplay #rp #sherlock roleplay #sherlock rp #johnlock rp #johnlock roleplay #sherlock #sherlock holmes #science #biology #biology of aging #biochemistry #molecular biology #genetics #telomeres

[twinktosterone]

okokokokokok i swear there’s a song with vocals that line up with the melodic riff thing in the intro (the little dede de De de) in telomeres sleep token but i can’t fucking find it smndjsbdjsbxjfb

#hELP #does this even exist or is my brain stuck on something it made up in its own #sleep token #this place will be become your tomb #telomeres #telomeres sleep token

[polteergeistt]

This fucking solo istg

#XHY CAN'T MY FINGERS MOVE FASTER I'M GONNA CRY #DO I NOT JACK OFF ENOUGJ. IS THAT IT. #fucking hell #i know it #it's not that fast #it's doable #telomeres

[melit0n]

So I just listened to Telomeres for the second time since I got into Sleep Token (which is like, 3, 4 years ago now?), since the first time I didn't like it as much, and why does that shit hurt so much??

The whole "This is the start of something" and then you get hit with such an emotionality heavy riff had me sat there with tears building up and a sob wracking through my chest. Sleep Token is soulful to me, but I don't think any of their songs have ever gotten me like that before, especially one I didn't previously like all too much. Like ow dude. That ones got a kick to it

#I was listening over it because I'm working on my SFX post and then just #bam #that #I'm not even entirely sure why that got me in my feelies #it just hurt #and of course it's the one where Vessels' geeked out about Chemistry and biology in the title #because there is no way someone who isn't/was a chemistry or biology major is remembering that word and knowing what it means #Telomeres is the bit at the end of a chromosome that keeps it from getting frayed #haven't a bloody clue what he means with that but it hurts #sleep token #vessel #telomeres