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dailyfigures · 2 months
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Kujo Jotaro ; JoJo's Bizarre Adventure ☆ Good Smile Company
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rileyverse · 8 months
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asmr
I found this creator during a random youtube search and figured my readers would absolutely love this persons voice so, like..*jazzhands*
I really recommend " let me read you to sleep"
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thinkin-in-petals · 1 year
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So what are things you have learnt ever since you have turned 18?
Love is not enough
Hyperfocusing on a goal will make you miserable
You won’t have your life figured out after your studies
Real connections are hard to find
Pain is inevitable
Patience provides peace
- jba
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3dlandscape · 2 years
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DEM SPATIAL RESOLUTION MEAN FOR FLOOD MODELLERS
Flood models reflect an actual land surface using DEM data. The amount of land that each grid cell in a DEM can represent is referred to as its spatial resolution. A grid cell that has a spatial resolution of 10 meters thus represents an actual land area that is 10 by 10 meters. The labels "low resolution" and "high resolution" are relative. A "lower" resolution dataset typically smoothes out topographic characteristics, while a "higher" resolution dataset implies considerably more preservation of land features (Environmental Systems Research Institute, Inc., 2016).
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In the hydrological and hydraulic modeling sector, DEM resolutions typically range from 1000m to 2m or less (Vaze, Teng, & Spencer, 2010). Here, we restrict our discussion to the national-scale flood maps from JBA, whose resolution ranges from 30m to 5m.
During the flood modeling process, flood modelers must make many crucial decisions. We research the assumptions made to depict complicated natural phenomena; we gather, validate, and incorporate input data; we create and test models, and we critically evaluate the outcomes. The DEM is essential to this applied and unreliable science. Determining where floods are most likely to cause problems for people and property and estimating how water interacts with the environment depend on high-quality DEM data.
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The precision and spatial resolution of the DEM affect the accuracy of forecasts of water depth (Vaze, Teng, & Spencer, 2010).
However, even while increased spatial resolution and accuracy frequently lead to better outcomes, these advantages cannot be taken into account separately, especially when taking into account how numerical flood models function. The physical processes of floods are represented by numerical models using many simulations, which, depending on the size of the area, may number in the hundreds of thousands or more. The higher the geographical resolution, the more complicated the models are, and the more computer resources, processing time, file size, data storage, and cost are required (Environmental Systems Research Institute, Inc., 2016).
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The preservation of topographical landscape elements increases with increasing DEM resolution. This offers a clearer delineation of the floodplain, tiny streams, highways, and other restricted flow conduits that have a big impact on outcomes. High-resolution topographical data is becoming more widely available, although it's still not everywhere. These data frequently only cover nations and areas with significant populations and/or economic development. However, it makes sense to invest in them if there is a demand from customers and the market for higher resolution flood data as well as good quality and quantity of data.
JBA offers 5m-resolution high-resolution flood maps for the US, Continental Europe, the UK, and the Republic of Ireland. Figure 3 shows how the flood maps for downtown Miami have changed as a result of using better-resolution data. The 5m map depicts water movement in intricate urban regions, while the 30m map does not, even if both images show the general areas at risk from floods. The validation of our modeling results using data on past and present flood events support a better, more in-depth understanding of floods from high-resolution maps.
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The combination of a number of factors allows us to meet the various requirements of clients despite the fact that flood modeling is a difficult science. Using higher-resolution resources has significantly improved the ability to assess flood risk in locations where we are confident in the quality and quantity of the input data, even if the resolution is not the only criterion for judging the quality of a dataset.
Those with access to the proper knowledge can ultimately make the most intelligent decisions. Speak with us about the variety of data we offer, its potential applications, our bespoke consulting choices, and how to decide which is the best choice for you.
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shounenwayoflife · 5 years
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Banpresto Jojo’s Bizarre Adventure Stardust Crusaders Jojo’s Figure 
Full disclosure. This is an affilitate link, so if you buy it, i helps me pay for college. 😂
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ikchen · 6 years
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A short essay on dwarfism in Ancient Egypt
We have a lot of sources from Ancient Egypt, especially the Old Kingdom (~2700-2200), that mention dwarves, their titles, their ranks, and their official functions in AE society.
The AE word for dwarf/pygmy/little person is “dng”, possibly pronounced “Deneg” or ”Daneg”. Alternatively, the word could also be written as “dAg”. Usually, as a Determinative, the sign A282 is used:
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Furthermore, there was a differenciation between what people tend to call “Pygmies” - which were usually brought* to Egypt for dance shows and celebrations (dng jbA,w), and Egyptian born dwarves. *These were highly requested artists, who were paid well and enjoyed high status.
During the Old Kingdom, dwarves were highly respected, and even thought to be magical, or blessed by the gods. The first signs of possible ableism and discrimination because of their stature crop up in New Kingdom wisdom texts* (texts that describe how to be a wise and well mannered person), where one would be admonished to not treat dwarves and people with disabilities badly. *one example would be papyrus B.M. 10474 
The fact that dwarvism doesn’t appear at all in AE medicinal texts, makes it probable that AE doctors knew dwarvism wasn’t an illness that needed to be cured.
The most famous artistic depiction of a dwarf is the Old Kingdom statue of Seneb and his family, found in his tomb. He was married to a member of the aristocracy, he fathered “normal” sons and enjoyed high rank in the royal court. His many titles reveal that he performed ritual duties as a priest and was denoted “Beloved of the King,” in addition to enjoying prestigious occupations  such as control over weaving activities in the palace, control of the seal (a byword for royal trust) and charge of ritual boats.
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Another dwarf, this time a so called “Pygmy”, that would be imported* from Punt, is mentioned in a letter, written by the young king Pepi II. 2284–2184 BC. The king expresses his excitement about getting to see the dwarf, and also concecrn about his safety and well-being. (Letter to Herchuf from Pepi II. - there are multiple good translations out there, personally I prefer the TLA one, but not everyone understands German.) *maybe imported is the wrong word, it would have been a great honor for the dwarf, to get to dance for the king of Egypt, and he would have been richly rewarded!
A third, very interesting depiction of a dwarf comes from the time of King Nectanebo II, the last ruler of the 30th dynasty (he reigned between 360–343 BCE, so in the Late Period). The naked figure of the dwarf Djeho, at life-size, measuring 120 cm, is carved on the lid of his sarcophagus, which is made out of granite and is of superb workmanship.
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Recommended reading:
Hans-Werner Fischer-Elfert: „Lache nicht über einen Blinden und verspotte nicht einen Zwerg!“ Über den Umgang mit Behinderten im Alten Ägypten. In: Max Liedtke (Hrsg.): Behinderung als pädagogische und politische Herausforderung. Historische und systematische Aspekte. 1996, S. 93–116.
C. Kozma: Dwarfs in Ancient Egypt. Hoboken NJ 2006.
V. Dasen: Dwarfs in Ancient Egypt and Greece. Oxford u. a. 2013 .
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vividracing · 3 years
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New Post has been published on https://www.vividracing.com/blog/top-5-best-exhaust-upgrades-for-the-toyota-tundra/
Top 5 Best Exhaust Upgrades for the Toyota Tundra
Upgrading exhaust components, or the entire system, on your Toyota Tundra is a great way to enhance the sound of your truck while also gaining some extra power. Replacing the OEM cat-back, for example, is one of the most popular first modifications we recommend to any new car enthusiasts. That’s because replacing the OEM cat-back with a free-flowing aftermarket exhaust system is a great way to increase horsepower and torque, while adding another element of style and enjoying a bolder soundtrack. When it comes to performance exhausts, most people look for just that: quality, power, and sound. The aftermarket, however, may be a bit daunting and so we have compiled the following list of products to help you along on your search. The five systems below will add great looks, incredible sounds, and performance to your Toyota Tundra over the factory setup.  Be sure to also browse Vivid Racing’s complete inventory of exhaust parts for your truck right here. 
1. Carven Exhaust Competitor Series Cat-Back
Carven Exhaust is leading the new era in the aftermarket performance exhaust industry. All Carven systems are handcrafted, built from stainless steel material, and assembled with TIG welding processes for the highest levels of rigidity, strength, and longevity. Each exhaust is expertly engineered to maximize performance so users can experience noticeable gains in horsepower and torque, as well as improved flow over the restrictive stock system. The Carven Competitor Series Cat-Back Exhaust for the Toyota Tundra is designed to deliver all that and more. It’s crafted from corrosion-resistant 304 stainless steel and features a 4-inch ceramic-coated black exhaust tip for added styling. This system delivers a well-rounded, aggressive tone at idle, cruising, and upon acceleration with minimal in-cabin noise. That means you can enjoy a loud exhaust without getting a headache from all that interior drone ­– not to mention, you can actually hear your passengers and radio. Though, with such an attractive-sounding system, you may not even want the latter.
Features: 
Deep aggressive tone with minimal drone
Improves exhaust flow over stock system
Boosts horsepower and torque figures
Carven signature high-flow muffler design
Crafted using high-quality 304 stainless steel
Includes a 4-inch ceramic black exhaust tip
Single side exit exhaust
Direct bolt-on installation
Buy It Here! 
2. Doug Thorley Long Tube Tri-Y Headers
This complete header kit from Doug Thorley will deliver huge increases in power for your Toyota Tundra. Featuring the Doug Thorley Headers’ original design, the 4:2:1 Tri-Y Header kit is engineered to match your engine’s firing order to maximize exhaust scavenging – the complete expulsion of gases on the exhaust stroke. The strategic design implemented here creates more usable power and torque for your truck than any other header on the market, making it a top choice for enthusiasts who want the most bang for their buck. The Tri-Y (or 4 into 2 into 1) style headers by design will noticeably boost the power of your truck’s engine across the widest RPM band possible. That is the true beauty of the design and that is why this header kit made it on our list of exhaust upgrades for your truck.
These Tri-Y Headers are designed with an emphasis on maximum low and mid-range torque, while making generous horsepower throughout the RPM range. The 4:2:1 Tri-Y header design makes it the ideal choice for trucks, tow-rigs, RV’s, and most street applications. The collector design makes this header one of Doug’s most efficient systems, which means you will see improvements both on the dyno and at the pump. This kit includes ceramic-coated long-tube tri-y headers and adapters to connect the headers to your Tundra’s factory y-pipe. To make these headers last, Doug Thorley built them using industry-leading 14-gauge steel tubing with 3/8-inch thick flanges. To top that all off, these headers come beautifully ceramic coated to greatly reduce underhood temperatures and protect them from the environment.
Features: 
Header Style: 4:2:1 Long-Tube Tri-Y Header
Material: Premium Steel
Finish: Silver Ceramic Coated
Primary Tube Diameter: 1-5/8″
Primary Tube Gauge: 14 Gauge
Collector Attachment: 3 Bolt Flange
Collector Diameter: 2-1/2″
Flange Thickness: 3/8″
Buy It Here! 
  3. Flowmaster Outlaw Extreme Cat-Back System
The Flowmaster Outlaw Series Cat-Back is the brand’s most aggressive, race-oriented system perfect for drivers seeking loud sound levels. If you are looking for increased power figures, better throttle response, a boost in MPG, and the most famous exhaust tone in the automotive world, Flowmaster is the way to go. The large-diameter mandrel-bent pipes deliver a restriction-free exhaust flow that is a much greater improvement over the stock system. Flowmaster’s Outlaw exhaust systems are designed to mount behind your Tundra’s factory catalytic converters for 50-state emissions legality. These systems are mandrel-bent for maximum performance and include specially selected high-performance mufflers to deliver the sound associated with that series. The Outlaw Cat-Back, for example, delivers an ultra-aggressive sound from the interior out and is best suited for those who wish to be heard before they are seen. Designed for an easy fit, these systems include all of the necessary parts and hardware for easy installation.
Features: 
Deep aggressive interior and exterior tone
Mandrel-bent stainless steel construction
Race-proven Outlaw muffler technology
Dual inlet muffler flows into 3-inch turndown tailpipe
Extreme sound for extreme lifestyles
Uses the factory hanger locations
Lifetime Limited Warranty
Quick and easy installation
Buy It Here! 
4. Stainless Works Redline Cat-Back Exhaust
  Take your Toyota Tundra to the ultimate level with the Stainless Works Redline Series Cat-Back Exhaust System. This exhaust is designed to maximize the volume and tone of your truck’s engine while still eliminating any unwanted drone in the interior. Stainless Works has engineered a drone-free and aggressive muffler for this system specifically designed for the 5.7-liter engine. If you are looking to get a highly assertive sound out of your ride, the Redline Series is here to deliver a scorching soundtrack that is better suited to the size and nature of the Toyota Tundra.
The Redline Series exhaust system features large-diameter mandrel-bent pipes, dual mufflers, and dual 4-inch black-out slash-cut double wall tips. The smooth CNC mandrel bends optimize exhaust flow to offer better fuel efficiency together with increased power across the entire RPM range. Designed to fit the Toyota Tundra’s factory connection points, this cat-back exhaust is built from corrosion-resistant 304 stainless steel and is completely TIG welded for the utmost in strength and beauty. The welded joints help to ensure a leak-free system and the solid steel construction resists rust so you can rest assured that this system will look and perform at its best for a long time.
Features:
1-7/8″ Primary tubes
3″ Mandrel-bent tubing
Aggressive exhaust note
Excellent fitment for easy installation
Black powder-coated exhaust tips
304 Stainless steel construction
TIG-welded for beauty and strength
Buy It Here! 
5. JBA Racing Headers Stainless Steel Exhaust
JBA Racing Headers is one of the most trusted names in the aftermarket exhaust industry because of its unwavering commitment to manufacturing excellence. JBA’s product designs are original, innovative, and always deliver on power, quality, fitment, durability, and smog legality. The JBA 2.5″ Stainless Steel Exhaust System for the Toyota Tundra will give your truck an enhanced appearance, improved throttle response, and proven power gains in the form of increased horsepower and torque figures. This is all thanks to the high-flow stainless steel mufflers and large diameter stainless steel mandrel-bent tubing which replaces the Tundra’s restrictive factory system. This combination allows for enhanced airflow that directly translates to newfound power along with an aggressive exhaust note that is more suited to the Japanese automaker’s full-size pickup truck. Each kit is finished with polished chrome-plated 3-1/2-inch stainless steel dual side-exit tips that resist discoloring, along with high-quality hardware and an instruction guide for a simple bolt-on installation. 
Features: 
Large diameter stainless steel mandrel-bent tubing
Increased horsepower/ torque with improved throttle response
Stainless steel high flow muffler(s) – greater flow/durability
Delivers a powerful exhaust soundtrack
High-quality hardware kit included
Polished chrome stainless steel tip(s)
Uses factory style hangers for easy installation
Buy It Here! 
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linhgd9 · 3 years
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Global Automotive Exhaust Systems Market Research scope and Research methodology by Syndicate Market Research
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This Report Represents the worldwide Automotive Exhaust Systems market size (value, consumption, and production), splits the breakdown (data status 2014-2020 and forecast to 2027), by manufacturers, region, type, and application. This study also analyzes the market status, future trends, market drivers, market share, growth rate, opportunities and challenges, sales channels, distributors, risks and entry barriers, and Porter’s Five Forces Analysis which also includes coronavirus updates. It also has an In-depth analysis of the industry’s competitive landscape, restraints, detailed information about different drivers, and global opportunities. Key competitors included in Global Automotive Exhaust Systems Market are BENTELER International, Eberspacher, Tenneco, Faurecia, Calsonic Kansei, Magneti Marelli, Wuxi Longsheng Technology, Bekaert, BASF, MAHLE, Gibson Automotive, JBA Headers, MAGNAFLOW, Banks Power, CORSA Performance, Flowmaster Mufflers, Holley Performance P. 
The report covers key strategic Points Regarding developments of the market including acquisitions & mergers, agreements, partnerships, new type launches, research & development, collaborations & joint ventures, regional expansion of major participants involved in the Automotive Exhaust Systems market on a global and regional basis. This Automotive Exhaust Systems Market Report covers global, regional, and country-level market size, market shares, market growth rate analysis (include Reseaon of highest and lowest peak Market analysis), product launches, recent trend, the impact of covid19 on worldwide or regional Automotive Exhaust Systems Market. Both top-down and bottom-up approaches have been used to estimate and validate the market size of the Automotive Exhaust Systems market, to estimate the Automotive Exhaust Systems size of various other dependent submarkets in the overall market. Key players in the market have been identified through secondary research, and their market shares have been determined through primary and secondary research. All percentage shares split, and breakdowns have been determined using secondary sources and Basic primary sources
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Our Research Specialist gives you a Free PDF Sample Report copy as per your Research Requirement, also including impact analysis of COVID-19 on Automotive Exhaust Systems Business Industries
Advantage of requesting FREE Sample PDF Report Before purchase
A brief introduction to the research report and Overview of the market
Syndicate Market Research methodology
Graphical introduction of global as well as the regional analysis
Selected illustrations of market insights and trends.
Know top key players in the market with their revenue analysis
Example pages from the report
The study objectives of Global Automotive Exhaust Systems Market are:
To split the breakdown data by regions, type, manufacturers, and applications.
To identify significant trends, drivers, influence factors in global and regions.
To analyze and research the global Automotive Exhaust Systems status and future forecast, involving, production, revenue, consumption, historical, and forecast.
To analyze the global and key regions’ market potential and advantage, opportunity, and challenge, restraints, and risks.
To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market.
To present the key Automotive Exhaust Systems manufacturers, production, revenue, market share, and recent development.
Global Automotive Exhaust Systems market report presentation has been estimated at length and according to expert analysis, is anticipated to entail an impressive growth of xx million USD in 2021 and is projected to further reach a total growth estimation of xx million USD through the forecast till 2027, growing at a CAGR of xx%, and you get accurate CAGR according to Automotive Exhaust Systems market size which actual exist
Scope of Report:
Automotive Exhaust Systems Market 2021 global industry research report is a professional and in-depth study on the market size, growth, share, trends, as well as industry analysis. The report begins with an overview of the industry chain structure and describes the upstream. In addition, the report introduces a market competition overview among the major companies and company profiles, besides, market price and channel features are covered in the report. Also, the report analyses market size and forecast in different geographies, types, and end-use segments. Furthermore, market size, the revenue share of each segment, and its sub-segments, as well as forecast figures are also covered in this report.
Automotive Exhaust Systems Analysis: By Applications
Passenger Car, Commercial Vehicle
Automotive Exhaust Systems Market: By Product
Muffler, Exhaust Pipe, Other
Automotive Exhaust Systems Global Market: By Region
North America
U.S.Canada
Rest of North America
Europe
UK
Germany
France
Italy
Spain
Rest of Europe
Asia Pacific
China
Japan
India
Southeast Asia
Rest of Asia Pacific
Latin America
Brazil
Argentina
Rest of Latin America
The Middle East and Africa
GCC Countries
South Africa
Rest of Middle East & Africa
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Table of Content include Automotive Exhaust Systems Market Worldwide are:
1 Study Coverage 1.1 Automotive Exhaust Systems Product 1.2 Key Market Segments in This Study 1.3 Key Manufacturers Covered 1.4 Market by Type 1.4.1 Global Market Size Growth Rate by Type (Muffler, Exhaust Pipe, Other) 1.5 Market by Application 1.5.1 Global Market Size Growth Rate by Application (Passenger Car, Commercial Vehicle) 1.6 Study Objectives 1.7 Years Considered
2 Executive Summary 2.1 Global Automotive Exhaust Systems Market Size 2.1.1 Global Automotive Exhaust Systems Revenue 2013-2025 2.1.2 Global Automotive Exhaust Systems Production 2013-2025 2.2 Automotive Exhaust Systems Growth Rate (CAGR) 2018-2025 2.3 Analysis of Competitive Landscape 2.3.1 Manufacturers Market Concentration Ratio (CR5 and HHI) 2.3.2 Key Manufacturers 2.3.2.1 Manufacturing Base Distribution, Headquarters 2.3.2.2 Manufacturers Product Offered 2.3.2.3 Date of Manufacturers Enter into Market 2.4 Key Trends for Markets & Products
3 Automotive Exhaust Systems Market Size by Manufacturers 3.1 Production by Manufacturers 3.1.1 Production by Manufacturers 3.1.2 Production Market Share by Manufacturers 3.2 Revenue by Manufacturers 3.2.1 Revenue by Manufacturers (2013-2018) 3.2.2 Revenue Share by Manufacturers (2013-2018) 3.3 Price by Manufacturers 3.4 Mergers & Acquisitions, Expansion Plans
4 Automotive Exhaust Systems Production by Regions —–contd—
5 Automotive Exhaust Systems Consumption by Regions —–contd—-
6 Market Size by Type —–contd—
7 Market Size by Application 7.1 Overview 7.2 Global Breakdown Dada by Application 7.2.1 Global Consumption by Application 7.2.2 Global Consumption Market Share by Application (2013-2018)
8 Manufacturers Profiles —–contd—
9 Production Forecasts —–contd—
10 Consumption Forecast —–contd—
11 Value Chain and Sales Channels Analysis 11.1 Value Chain Analysis 11.2 Sales Channels Analysis 11.2.1 Automotive Exhaust Systems Sales Channels 11.2.2 Distributors 11.3 Customers
12 Market Opportunities & Challenges, Risks and Influences Factors Analysis 12.1 Market Opportunities and Drivers 12.2 Market Challenges 12.3 Market Risks/Restraints 12.4 Key World Economic Indicators
13 Key Findings in the Global Automotive Exhaust Systems Study
14 Appendix 14.1 Research Methodology 14.1.1 Methodology/Research Approach 14.1.1.1 Research Programs/Design 14.1.1.2 Market Size Estimation 14.1.1.3 Market Breakdown and Data Triangulation 14.1.2 Data Source 14.1.2.1 Secondary Sources 14.1.2.2 Primary Sources 14.2 Author Details 14.3 Disclaimer
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factmrresearch1 · 3 years
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PRIMARY BILIARY CHOLANGITIS TREATMENT MARKET
Primary biliary cirrhosis, also known as primary biliary cholangitis is a chronic liver disease, which causes liver inflammation, fibrosis, and obstruction in the bile duct leading to destruction of small bile ducts within liver. Cause for primary biliary cirrhosis can be autoimmunity, infection and/or genetic predisposition. Symptoms of primary biliary cirrhosis include itching, osteoporosis, elevated serum cholesterol, and malabsorption of fat, and fat soluble vitamins, which can advance to hepatomegaly, hyperpigmentation, splenomegaly, jaundice, sicca syndrome or Kayser-Fleischer rings. Primary biliary cirrhosis develops over time and may cause the liver to stop working completely in later stages.
The global primary biliary cholangitis treatment market size was valued at US$ 526.4 million in 2017, and is expected to witness a CAGR of 36.3% during the forecast period (2018 – 2026).
Figure 1. Global Primary Biliary Cholangitis Treatment Market Value Analysis (US$ Mn) and Forecast and Absolute $ Opportunity
                        Source: Coherent Market Insights Analysis (2019)
Increasing number of pipeline studies is expected to drive the primary biliary cholangitis treatment market growth
Increasing pipeline studies to develop prominent treatments for rare diseases such as primary biliary cholangitis are expected to boost the primary biliary cholangitis treatment market size. For instance, in October 2018, CymaBay Therapeutics, Inc., initiated placebo-controlled and randomized phase 3 clinical trial for seladelpar 5-10mg. The aim of the study was to evaluate safety and efficacy of seladelpar in patients with primary biliary cholangitis (PBC) and to determine inadequate response or intolerance to ursodeoxycholic acid (UDCA). The study is estimated to complete in December 2021.
Moreover, in January 2017, GlaxoSmithKline (GSK) initiated phase 2 clinical trial to study the efficacy, safety, and tolerability of GSK2330672 administration for the treatment of pruritus (itch) in participants with primary biliary cholangitis (PBC). GSK2330672 is a selective inhibitor of human ileal bile acid transporter (IBAT). The study is estimated to complete in April 2020.
Primary Biliary Cholangitis Treatment Market- Regional Analysis
Regional segmentation of the global primary biliary cholangitis treatment market comprises North America, Latin America, Europe, Asia Pacific, Middle East, and Africa.
North America is anticipated to witness lucrative primary biliary cholangitis treatment market growth, owing to growing initiatives by market players to develop advance treatment options for PBC. For instance, in October 2016, TARGET PharmaSolutions, Inc., U.S.-based Company, in collaboration with Intercept Pharmaceuticals, Inc., launched its TARGET-PBC (Primary Biliary Cholangitis) platform. TARGET-PBC platform has been created to improve the understanding of real world treatment patterns in PBC.
Asia Pacific is also expected to witness significant growth in the primary biliary cholangitis treatment market. For instance, in 2017, the Japanese Biliary Association (JBA) and the Intractable Hepatobiliary Disease Study Group of Japan estimated that there were 2,000 to 3,000 patients with PBC in Japan. Also, in 2017, Japanese researchers planned to collect DNAs from Japanese PSC patients, to examine difference in genetic background between the East and the West of Japan.
Europe is expected to witness significant market share in the market, owing to rising initiative by professional organizations to create awareness among the healthcare professionals to treat the patients suffering from rare diseases such as primary biliary cholangitis. For instance, April 2018, the British Society of Gastroenterology and UK-PBC entered into strategic partnership to develop a comprehensive guidelines for the treatment of primary biliary cholangitis. The guidelines are mainly designed for gastroenterologists and herpetologists engaged in providing treatment to the patients with PBC.
Figure 2: Global Primary Biliary Cholangitis Treatment Market Value (US$ Mn), By Region, 2017
Source: Coherent Market Insights Analysis (2019)
Primary Biliary Cholangitis Treatment Market - Competitive Landscape
Key players operating in the primary biliary cholangitis treatment market include Novartis AG, Bristol-Myers Squibb, NGM Biopharmaceuticals, Lumena Pharmaceuticals, Inc., TARGET PharmaSolutions, Inc., Intercept Pharmaceuticals, Inc., Teva Pharmaceutical Industries Ltd, Retrophin, Inc., Calliditas Therapeutics AB., and GlaxoSmithKline (GSK) pharmaceutical.
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dailyfigures · 1 year
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Kira Yoshikage ; Jojo's Bizarre Adventure ☆ Di molto bene
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sriramnanda-blog · 4 years
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PRIMARY BILIARY CHOLANGITIS TREATMENT MARKET ANALYSIS
Primary biliary cirrhosis, also known as primary biliary cholangitis is a chronic liver disease, which causes liver inflammation, fibrosis, and obstruction in the bile duct leading to destruction of small bile ducts within liver. Cause for primary biliary cirrhosis can be autoimmunity, infection and/or genetic predisposition. Symptoms of primary biliary cirrhosis include itching, osteoporosis, elevated serum cholesterol, and malabsorption of fat, and fat soluble vitamins, which can advance to hepatomegaly, hyperpigmentation, splenomegaly, jaundice, sicca syndrome or Kayser-Fleischer rings. Primary biliary cirrhosis develops over time and may cause the liver to stop working completely in later stages.
The global primary biliary cholangitis treatment market size was valued at US$ 526.4 million in 2017, and is expected to witness a CAGR of 36.3% during the forecast period (2018 – 2026).
Figure 1. Global Primary Biliary Cholangitis Treatment Market Value Analysis (US$ Mn) and Forecast and Absolute $ Opportunity
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Source: Coherent Market Insights Analysis (2019)
Increasing number of pipeline studies is expected to drive the primary biliary cholangitis treatment market growth
Increasing pipeline studies to develop prominent treatments for rare diseases such as primary biliary cholangitis are expected to boost the primary biliary cholangitis treatment market size. For instance, in October 2018, CymaBay Therapeutics, Inc., initiated placebo-controlled and randomized phase 3 clinical trial for seladelpar 5-10mg. The aim of the study was to evaluate safety and efficacy of seladelpar in patients with primary biliary cholangitis (PBC) and to determine inadequate response or intolerance to ursodeoxycholic acid (UDCA). The study is estimated to complete in December 2021.
Moreover, in January 2017, GlaxoSmithKline (GSK) initiated phase 2 clinical trial to study the efficacy, safety, and tolerability of GSK2330672 administration for the treatment of pruritus (itch) in participants with primary biliary cholangitis (PBC). GSK2330672 is a selective inhibitor of human ileal bile acid transporter (IBAT). The study is estimated to complete in April 2020.
Primary Biliary Cholangitis Treatment Market- Regional Analysis
Regional segmentation of the global primary biliary cholangitis treatment market comprises North America, Latin America, Europe, Asia Pacific, Middle East, and Africa.
North America is anticipated to witness lucrative primary biliary cholangitis treatment market growth, owing to growing initiatives by market players to develop advance treatment options for PBC. For instance, in October 2016, TARGET PharmaSolutions, Inc., U.S.-based Company, in collaboration with Intercept Pharmaceuticals, Inc., launched its TARGET-PBC (Primary Biliary Cholangitis) platform. TARGET-PBC platform has been created to improve the understanding of real world treatment patterns in PBC.
Asia Pacific is also expected to witness significant growth in the primary biliary cholangitis treatment market. For instance, in 2017, the Japanese Biliary Association (JBA) and the Intractable Hepatobiliary Disease Study Group of Japan estimated that there were 2,000 to 3,000 patients with PBC in Japan. Also, in 2017, Japanese researchers planned to collect DNAs from Japanese PSC patients, to examine difference in genetic background between the East and the West of Japan.
Europe is expected to witness significant market share in the market, owing to rising initiative by professional organizations to create awareness among the healthcare professionals to treat the patients suffering from rare diseases such as primary biliary cholangitis. For instance, April 2018, the British Society of Gastroenterology and UK-PBC entered into strategic partnership to develop a comprehensive guidelines for the treatment of primary biliary cholangitis. The guidelines are mainly designed for gastroenterologists and herpetologists engaged in providing treatment to the patients with PBC.
Figure 2: Global Primary Biliary Cholangitis Treatment Market Value (US$ Mn), By Region, 2017
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Source: Coherent Market Insights Analysis (2019)
Primary Biliary Cholangitis Treatment Market - Competitive Landscape
Key players operating in the primary biliary cholangitis treatment market include Novartis AG, Bristol-Myers Squibb, NGM Biopharmaceuticals, Lumena Pharmaceuticals, Inc., TARGET PharmaSolutions, Inc., Intercept Pharmaceuticals, Inc., Teva Pharmaceutical Industries Ltd, Retrophin, Inc., Calliditas Therapeutics AB., and GlaxoSmithKline (GSK) pharmaceutical.
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thinkin-in-petals · 6 years
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I'm done with feeling nothing.
It's a constant spiral and it doesn't make any sense. I feel so empty and alone. So I need to go out and meet people and talk to people.
But the thing is: "I need to" in order to improve my life but "I don't want to".
I feel so exhausted constantly trying to be the best version of myself when I see is the worst version of myself. Like I am sitting here every fucking saturday staring at my wall. Wandering what the actually fuck I am doing.
I get so frustrated because I can't do shit. I'm just sitting here and staring.
Nothing more, nothing less.
I either want to go out or do homework but I end up doing nothing. Because I get so tired of constantly trying to get my shit together and I feel too lonely afterwards causing me to skip homework.
This whole writing sounds like a joke but for real. This is real life. This is my life. How did I get here? When did this virus entered my brain? Because every time I try to figure out what I actually want it says:
"ERROR 404"
-jba
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dashielljohn · 5 years
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Learn Which Type of Exhaust System is Best for Your Car
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Driving a powerful vehicle is a treat for your senses. The feeling of G-powers maneuvering you into your seat as you quicken, the smell of consuming elastic, and seeing awed spectators all indicate one fulfilling tangible experience, yet it's the sound of a snarling exhaust system that truly gets your heart pumping. We offer a full scope of performance exhaust systems that take your vehicle to the following dimension, regardless of whether you drive an every day suburbanite or a shiny new games vehicle. Before you go out on the town to shop for the best exhaust systems for your vehicle, investigate the various types of systems and figure out how a Performance fumes can enhance your capacity, effectiveness, and sound. 
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Skunk2 Megapower Exhaust System:
Ideal for a sports car compact, the Skunk2 Megapower system is stainless steel and highlights Japanese styling. Opening up your motor stream with this system will convey dyno-demonstrated strength increases and that's only the tip of the iceberg. This system is mechanically welded for unrivaled quality and upheld by a Limited 1-Year Warranty. In addition, it looks great and sounds great - can't beat that!
Corsa Exhaust System:
Accessible in three unique styles, Xtreme, Sport, and Touring, you'll certainly have the capacity to locate the correct sound profile you need for your vehicle with a Corsa Exhaust system. The mandrel-bowed tubing of this framework amplifies wind current while limiting back pressure and upgrading mileage. What's more, furthermore, each set-up comes uniquely crafted to suit your vehicle. This system is made in the USA and is exhaust cloud legitimate in every one of the 50 states.
Pacesetter Monza Exhaust System:
For a subcompact or sports vehicle, redesigning your drive and torque is as basic as introducing a PaceSetter Monza Exhaust System. 16-Gauge Aluminized Steel is manufactured into additional huge high-stream channels for ideal wind current. Chrome exhaust tips are incorporated with each order, and this set it gladly made in America.
JBA Performance Exhaust System:
With a super-wide diameter and mandrel-twisted tubing, the Steel JBA Performance Exhaust System will augment your drive and torque all through your RPM extend. Your mileage and throttle reaction will likewise progress. This system is supported by a Lifetime Warranty, and it's legitimate in each of the 50 states.
Gibson Performance Exhaust System:
Netting you up to 20 extra horsepower, just as up to 20 foot pounds of torque, the Gibson Performance Exhaust System is for drivers who like to dive, instead of stick a toe in the pool. A completely welded superflow suppressor brings better volume productivity and totally unhindered airflow. In addition, a T304 high-cleaned Stainless Steel tip truly stops people in their tracks as you cruise by.
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babysfirstactics · 4 years
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Name Generation
As I was outlining the story (read: I have four lines written), I was realizing that having characters named “Protagonist” and “Brother2 ” and “Close Friend” was a good way to get myself confused later. Unfortunately, naming characters is not my strong suit. Instead of taking the easy route and googling a dungeons and dragons name generator, I decided to use a neural network to generate the names of some of the main characters. I used textgernn, a Python module that you can train with text from any source, and all you need is a list separated by line breaks. It’s neat! 
Another reason I wanted to use a neural net is because in the original Final Fantasy Tactics, the names sound a bit off. Some of them are pretty normal, or they’re just odd spellings of normal names. But others... I mean, seriously, listen to these: Olyffe, Yedythe, Systeleley, Aylmer, Chartain, and Roundelph? Maybe these are normal names, and I’m just an ass, but come on. They’re weird, right? 
But I digress. To train my neural network, I pulled as many baby names from the internet as I could manage without going insane, and added in the FFT names for a bit of spice. As much as I wanted to add in a lot of multicultural names, finding names common in even Europe and Mexico was surprisingly difficult, so I stuck with a list of mostly common US names and a shorter list of common names in Mexico. (If you know of a list of names from many other countries, especially in Asia or Africa, I would love to know!) I ended up with a list of 1751 unique female names. (I did the same for males, but I needed a name for the protagonist’s sister first, so we’ll stick with female names for this post.)
It took me a while to figure out the input the neural net liked. textgernn has a “temperature” setting which is a kind of proxy for how “creative” it is. At very high temperature, you get output like this: 
bAn os ePl Nir al e Tr a ael edl Sa eaeeCbre Eea eae eeneyle nneen ltn ce Yei neae itn
y Eve fae ia dCee ai dee
Ok, nice try! It’s like, some of these are nearly English names, if you squint! So I turned the temperature down a bit and what I got was much more reasonable:
Mhisore Fhine Jostay Abury Estonnnah Qulena Smersys Dianann Luy Dyslen Aberie Edarith Herlelina Pindittat Ayncee Feriulne Dorlowa Wvaree Veciar Harlde Rye Haetsl Jonne Jveleda Nety Everha AKinna Laudlee Loretia Ppeley Edetoh Norlime Heceshe Mersny Jelemet Aerle Kelish Alycica Retslin Yleley Imadca Btorsad Ginla Peinryn Ga Tarli Mansine tttin Slenen Jba Srorsly
Now, please don’t name your daughter Srorsly, but a lot of these are just about pronounceable, and a few could even be confused for real names. Edarith and Dianann sound like they’ve already been hanging out in middle-ages European fantasy land for a while now. A little lower temperature, and the net just spits out the names you gave it. 
I did manage to find a sweet spot, and then curated the names a bit to make them a little more palatable. Here’s a few from the first 100 names it came up with.
Adary Alaryn Alia Alorin Anaria Attera Beriene Berly Brarie Brilis Brishie Brites Carilie Cherlia Cleista Coritones Corryn Cwere Dameve Dorie Edarte Edet Elancey Elina Elinsy Elony Emelhin Emerlon Emhey Ferlry Flin Gerree Gindly Ginlorin Gudrlin Hadgey Hainie Hareda Helina Helne Hemeley Herlan Herlil Hlorel Idecer Idrley Janlyin Jerice Jonema Jonin Joris Karince Kerler Kertrie Kynee Kyney Kyrin Laly Laritue Linann Lindorl Linsle Llone Lyne Masthine Melde Melelle Meria Nerna Nile Pelina Pellaine Perie Qurnne Rerly Reryta Ricey Rinnsin Rorily Saslie Sdastey Stalee Syney Tare Tcerin Telely Teralin Tinene Tisha Trin Whann Wilorte Winda Wlorda Wunclie
Not bad, right? As far as I know, none of these are real names, but if you want to run them through that USA name database, be my guest. Despite being completely fake, most of them sound pretty plausible for a fantasy realm. 
So there you have it! Weird, kinda real-sounding names made by a neural net. I imagine that if the game ever comes to fruition, I’ll use a lot of these for the names of the generic, randomly generated characters.
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panchalpooja-blog · 5 years
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Light Vehicle Exhaust & Emissions Systems Market Size – Industry Analysis, Share, Growth, Trends, And Forecast 2015 – 2023
Overview
The research report provides valuable insights into demand drivers, geographical outlook, and competitive landscape of the Light Vehicle Exhaust & Emissions Systems Market for the 2015 – 2023 forecast period. Further, it throws light on restraints as well discusses opportunities at length that are likely to come to the fore over the forecast period. The analysis thus provided helps Market stakeholders with business planning and to gauge scope of expansion in the Light Vehicle Exhaust & Emissions Systems Market over the forecast period.
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The SWOT analysis of key vendors along with a detailed profile of key vendors based on business overview, financial status, and product portfolio helps to gauge competitive dynamics in the Light Vehicle Exhaust & Emissions Systems Market. This analysis helps to gauge growth strategies to be employed by prominent vendors in the Light Vehicle Exhaust & Emissions Systems Market, and scope of collaborations and partnerships between these players.
The report includes an exhaustive list of top players in the Light Vehicle Exhaust & Emissions Systems Market:
Flowmaster, Inc., Magnaflow, MBRP Inc., Borla, Gibson Performance, Inc., Gale Banks Engineering. INC., advanced FLOW engineering, Inc., JBA Performance Exhaust, and Gibson Performance, Inc. among others.
Further, Market share projections and changing competitive hierarchy in the Light Vehicle Exhaust & Emissions Systems Market until the end of the forecast period are vital offerings of this report.
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Key Questions Answered in the Light Vehicle Exhaust & Emissions Systems Report
What is the revenue projections in the Light Vehicle Exhaust & Emissions Systems Market over the forecast period?
Which product segment is likely to garner maximum share in the Light Vehicle Exhaust & Emissions Systems Market over the forecast period?
Which regional segment is likely to hold the leading share in the Light Vehicle Exhaust & Emissions Systems Market over the assessment period?
What are winning strategies adopted by leading players in the Light Vehicle Exhaust & Emissions Systems Market to consolidate their foothold?
What are some prominent developments observed in the Market?
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