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#intestinal tract healthy
jayrockin · 1 year
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without sounding as weird as possible, i'm curious about centaur bodily waste. since baby talita did not wear pants does this mean she just went anywhere?? did she use a......litter box? do baby centaurs wear diaper-adjacent clothing in their home planet to prevent messes or is it like a clean rabbit situation fhdjfjdj
TMI warning for discussion of bodily waste, but poop is a normal part of being an alive thing so here you go:
Humans and scuds are the only alien sophonts with liquid metabolic waste, and centaurs specifically have an excretory tract similar to a bird. So, in a healthy individual, waste is usually relatively compact and pellet-like with a white smear of nitrogenous solids. They tend to be dry poops as well, because their unidirectional respiratory tract sheds exhaled water vapor faster than ours.
In a situation where a centaur is over-hydrated, or their body is trying to void an intestinal pathogen, it can get runny. Also similar to birds, they have an occasional wetter poop that is actually them voiding a branch of their upper intestine called the cecum, which absorbs excess water from their diet.
As for babies: larvae cling to their mom for 5 months until they pupate, and during that time they do little else besides eat silk and poop. Their anus is at the end of a curly "tail" they that instinctively lift while pooping, so not all of it gets on their parent. Once larvae are large enough (rat sized?) for their waste to start being an inconvenience that early maternity clothes can't handle, they're positioned in a single fabric sling that supports their butts while they cling to mom. These slings get exchanged and cleaned regularly. For larger larvae individual tailbag diapers might be used, though the latter is a more common practice among settled centaurs than nomads. I drew some maternity clothes here.
After pupation, practices vary even more. Like a human baby, they don't have great control over their bowels, but unlike a human baby, they have the dexterity to wriggle out of garments they don't like. Diapers have to be acclimatized to, and imago who wore individual diapers as larvae are more likely to put up with them. These resemble chicken diapers, with a stiff "pocket" behind the butt. Nomads more often let them run around in the great outdoors naked, weather permitting. Settled centaurs prefer diapers but may also have a nursery room with fiber bedding and/or a training toilet that youngins are kept inside. Very young imago are sometimes let outside pantless with supervision to just… go wherever. Maybe the garden, free pest control and fertilizer! Put those infants to work!
Talita was put in human diapers as soon as she started tolerating them, but there was a phase where they were keeping her shut inside a room of the foster home with a tarp on the floor....
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napfordinner · 6 months
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My lovely friends, this is a friendly evidence-based post pertaining to the risk reduction of a few well-known health effects of 4n4 and mia. Including: Amenorrhea (loss of regular menstrual period), anaemia, digestive upset, dehydration, electrolyte imbalance, general well-being, and osteoporosis. It is quite a long post, but please let me know if there’s any other information you would like me to cover. 💕
🪐 Vitamins and Supplements:
• A-Z Multivitamin. Is beneficial for supplementation. For example, Vitamin C is a vitally important vitamin for the body’s connective tissues, including the maintenance of healthy bones and teeth, cellular formation and maturation, resistance to infection, and an increased ability to heal. Additionally, B12 contributes to an adequately functioning nervous system, bone marrow, and intestinal tract. It also acts to increase metabolism of protein, carbohydrates, and fats. Finally vitamin B2 when combined with Vitamin A promotes good vision and healthy skin, as well as assists in metabolising proteins and fats at a cellular level.
• Calcium and Vitamin D. Seek a preparation which offers 1000mg of calcium and 10-20mcg (400-800 iu) of vitamin D. Vitamin D increases the bodies efficacy during the absorption, retention, and metabolising of calcium. Calcium of course being vital for bone integrity and imperative for the prevention of osteopenia/osteoporosis.
• Iron. An appropriate iron intake will restore the functionality of red blood cells, allowing the proper oxygen transportation around the body, increase focus, energy, athletic performance, and sleep. Having a sufficient iron store will alleviate some commonly experienced symptoms of low iron including fatigue, dizziness, pallor, and shortness of breath. It may also reduce the sensation of cold hands and feet.
• Potassium and Zinc. A lack of zinc impairs the ability to smell and taste. Connecting this impairment to nose blindness. For example, a lack of a sense of smell and taste may impair one’s own ability to detect their own bad breath, BO, and other unpleasant smells that others may be able to detect.
• Omega 3’s - Fish oil, Krill oil, Hemp oil, or Flaxseed oil. Improper dietary intake, or supplementation of omega 3 fatty acids will result in areas of epidermal (skin) dryness, hyperkeratosis, and hyperpigmentation. As well as the formation large scales expose underlying tissue, which are easily infected. The hair becomes sparse, dry, lusterless, and brittle, with a reddish tinge. Furthermore, nails become brittle and dull, tear production reduces, the tears are also significantly less oily leading to increased evaporation contributing to chronically dry, red, and itchy eyes.
If oil supplements are scary for you to intake due to calorie fears (there is only approx 25 calories in 2 average fish oil capsules). There are dietary sources of omega 3 that are relatively low calorie including chia seeds, edamame, and seaweed. However they provide little amounts in comparison to supplementation or traditional dietary sources such as fish, avocado, oils etc.
However this should also be considered when deciding whether to supplement omega 3’s - they stimulate the secretion of leptin, a hormone that decreases appetite and promotes the burning of fat. Through the enabling of conversion of dietary fats into body cells for burning as fuel.
🍄 Dietary Intake
•Bone broth (or vegetable broth if meat is not apart of your diet ☺️) I cannot stress how great bone broth is! Extremely low calorie, but incredibly nutrient-dense. It also acts to decrease the inflammation within the gut that many of us will experience due to our dietary habits. Including conditions such as constipation, gastroparesis, liver disease, bloating, abdominal pain, and stomach ulceration.
Bone broth also contains large amounts of protein, collagen, iron, vitamins A and K, fatty acids, selenium, zinc, and manganese. Protein being the most satiating macronutrient can decrease hunger and associated discomfort. Collagen and the variety of micronutrients within the bone broth contributes to joint and bone health. Bone broth will also contribute to hydration.
•Nutrient-dense foods including blueberries l are among the best sources of anthocyanins (antioxidants) that promote brain health and reduce the risk of cognitive decline. Additionally, red tomatoes and red capsicum (Peppers). Tomatoes are the richest source of lycopene, which is a type of carotenoid found in red fruits that has powerful antioxidant effect that may help protect against heart disease and certain types of cancer.
•Fibre is imperative for smooth gastrointestinal function, including regular bowel movements. Fibre is of course typically found in whole fruits and vegetables, beans/lentils, and whole grains. Low calorie fibre sources include: red kidney beans, carrot, and chickpeas. Psyllium, chia seeds are also good sources of fibre. Fibre supplants such as Metamucil may also aid to increase fibre intake. An adequate intake of fibre may reduce the dependence of laxative for bowel movements. Prolonged use of laxatives may create a dependency on them to even have a bowel movement.
🥥 Adequate Hydration
• The best way to ensure adequate hydration is simply by consuming enough water during the day. However, if plain water consumption is difficult, fluid intake will also suffice. Including fluid such as teas, flavoured/enhanced water, diet soft drinks, juices, etc. The optimal fluids to consume in addition to, or instead of simple water to ensure adequate hydration is mineral water, coconut water, or diet electrolyte replacements (Powerade/Gatorade, Pedialyte, Hydralyte). Correct hydration and electrolyte intake will reduce headaches, constipation, and muscle cramps/weakness.
❤️ Reproductive Health
•Amenorrhea is a common experience for those of us with a uterus. However it is imperative to understand that you are more than likely still ovulating despite the lack of a regular menstrual period. Therefore, contraception must still be used. Amenorrhea may be alleviated through dietary supplementation and small changes to the diet to include more micronutrients, but it may not be completely fixed unless there is an increase to body fat percentages.
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roansdreamary · 4 months
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Hello, I am writing this with urgency. Over the last few days, my cat Eva has suddenly developed a severe medical problem. She can not keep food or water down and has severe diarrhea, and is in pain. She had an X-Ray today and a spot in her GI tract looked highly suspicious for an intestinal blockage of some kind. I was told after by the Vet that she needs exploratory surgery in order to find/remove the potential obstruction and to diagnose her in general. I can’t afford it. Her medical bill from only a few basic diagnostics alone has already surpassed $1,000, and this doesn’t even include treatment. I will be forever thankful to anyone who can donate, Eva means the world to me and my only wish right now is for her to be healthy again!
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mysoullanguage · 1 year
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hellooo i wanted to ask if planets in the 6h influence appearance since the 6h represents health/physical body, etc?
great question, but i would argue it doesn't hold as much influence on appearance as 1h would. 6h is not only about health and the physical body but also energy, work ethic, and self-esteem. but, there are still some placements that could indicate some resonance to the physical body. however, we must differentiate that 1h comprises of physical features inherited from birth, whereas 6h comprises of things like diet and athleticism to alter your physical appearance. in other words, when a planet is in 6h, there are other things that influence the appearance, rather than being "born" with them (a 1h trait.) let's look below at an example below:
mars in 6h, where the native is competitive, athletic, and energetic. these people typically have a lot of pent-up energy with them that is not only exercised through their work but also through sport or some activity. they may be gym rats or people who take the sport seriously. with this placement, the native would focus on building their body and having a healthy diet. placement matters because if mars were in 1h, the native may have a big forehead/head and prominent brows or eyes from birth (aries = head.) this is not a placement blessed with good looks from birth, but rather worked on through exercise or other deciding factors such as diet
saturn in 6h, where the native may struggle with their diet and health, therefore resulting in an appearance more scrawny than others. virgo is associated with the digestive tract/intestine, and saturn typically debilitates what it touches. therefore, the stress put on the digestive system/intestine may directly affect appearance this way. as you can see, their appearance does not come from the fact saturn is in 6h alone, but because saturn in 6h (think diet, health, exercise) affects relevant issues of the diet/exercise/activity.
jupiter in 6h/venus in 6h, where the native may struggle (jupiter) or compromise (venus) with their diet. they may struggle with maintaining weight or losing it. venus doesn't indicate grandeur in eating as jupiter would, but venus can indicate someone really into food, therefore over-indulging in it.
hope this answers your question.
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radio-free-beth-sarim · 9 months
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I'm currently sitting on the boardwalk in Ocean City, MD. My family has always taken vacations here, and coming here as an adult is basically just me doing all the things I used to do as a kid, but also the things I wanted to because I couldn't... I was a kid. For a long time I just couldn't afford a vacation. I was bound to my job at the cost of my health. And that led to me getting sick when I just wasn't taking care of myself. Being as sick as I was, I wasn't sure I would ever come back here. There was no guarantee I'd recover, and a good possibility I would be dead by now. So I see being here as a triumph on several fronts. I can now afford to take a vacation, and I am now healthy enough to make it here.
Often I would entertain the idea that I was actually dead, watching the world from the afterlife as it just moved on past me. I came back to a world just similar enough to be familiar but different enough to feel like I'm out of place. I felt like a space alien when I tried to swipe my debit card at the supermarket the first time and they told me to tap. And I was just like "that works?"
I told the cashier I was "gone for a while" and they gave me a strange look. I can only imagine they thought I was just out of prison. I tell people now that "I spent five years dead for tax purposes" and that usually gets either a laugh, or a stranger look than the implication I was in prison. A win for me either way.
But returning to places after the passage of such time is bittersweet no matter the circumstances, and being on the Ocean City boardwalk is a good feeling but one that carries a twinge of sadness.
Arcades have always been my happy place. From the Dundalk skateland that had a Darkstalkers machine and an MVS cabinet to Aladdin's Castle where I spent so much money playing DDR, I always felt so at home and comfortable in those spaces. So being back at the boardwalk for the first time in so long, I had to go to the arcades here. I walked along the boardwalk, and man, it's different but in all of the important ways nothing changed. The weird t-shirts. The Thrashers fries. They're selling deep fried oreos now which I am sure is delicious, but the things that would do to my intestinal tract make me cringe in horror.
I stopped at just about every arcade on the way. All of them left me disappointed that they weren't like what I remember. It's all ticket games, coin pushers, or claw machine variants. If they're actual video games they're reworked versions of old school games like frogger or space invaders, or mobile games. I don't mean to sound all boomer about this, like these kids just don't know, that's not what I am complaining about. I saw a lot of kids having a ton of fun, and it was so good to see. The laughter and joy was a delight, and being in such a place is a wonderful experience. Somewhere among those kids is someone building those core happy memories that will make them love the place like I did. Arcades are an important space where, as the great Charles Entertainment Cheese once said, a kid can be a kid. And going to an arcade makes me feel like a kid again.
But being there was also a stark reminder that I am no longer young. The arcades I remember are out of fashion. Those games are niche now. They don't make it to America often, let alone the Ocean City boardwalk. I made it to Sportland, one of the arcades I went to most frequently. I saw more of the same coin pushers and ticket machines. The place changed. Of course it had. Everything changes. But I mourned those days. In a way I was mourning my youth. I found a single neglected Tekken 3 machine and made my Person play me in a first to five. They 5-0'd me. That's how bad I am at Tekken, I got 5-0'd by someone that doesn't play fighting games. But it was fun, and they were a good sport. I also let a kid beat me in Mario Kart, so that was cool. The kid had to be like 10-12. He was happy, and that made me feel good. I won my Person a weird sonic plush, too. I had a good time! A great time! But as I walked out of Sportland with that bittersweet feeling in my chest, I looked over at Marty's Playland, THE arcade I used to spend most of my time at, and I couldn't bring myself to go in. I need it to be just the same as I remember, even though I know it isn't. I need there to be a place unchanged by time, exactly as I remember it, even if it exists only in my mind. And I know that's not reality anymore.
Maybe this is what W.B. Yeats meant when he wrote "There is no country for old men."
But I saw a kid in an Electric Wizard shirt so there is definitely hope for the future somewhere.
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foxymoxynoona · 1 year
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hope your surgery goes well
Thank you <3 It's now scheduled for June 7 and I am utterly terrified. I'll put some details below the cut for those who don't mind medical talk and are curious. Recovery will be 8-10 weeks, though I've been warned it could be 6 months or more before I'm feeling myself again so I don't really have a projection about what this means for my writing yet.
Unfortunately the surgeon can't tell the best way to remove the tumor in my small intestines without going in, so I'll be having an open abdomen exploratory surgery. There are four potential surgical results, from an easy and simple removal or minor resection if the tumor is on a stalk like the endoscopic surgeons think, all the way up to a Whipple (a major procedure usually used for pancreatic cancer where they remove some of your organs even if they're healthy and reroute your digestive tract; it has lifelong dietary changes and risk of things like diabetes and enzyme production failure.) I'll be in the hospital for a week and recovery is rough for a Whipple, less rough for the lesser procedures. No matter what I'll be recovering from the abdominal incision and at least a minor resection. I really really really hope it can be a lesser surgery.
I hate this. I'm terrified. The fact I won't know what they do to me until I wake up either with a nasal feeding tube or without one is agony. I'm sick and miserable in the meantime dealing with all sorts of symptoms; it's not a surgery I can opt out of with all my current health problems. We're taking blood samples every two weeks in the meantime to make sure I'm not bleeding out too quickly again and I'm setting up everything I can to run smoothly at home while I'm recovering. I'm out of work right now on medical leave until late July or August depending on which surgery I wind up with.
💔 This isn't fun. 💔
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foggy-milk · 11 months
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Haven’t been too active been taking care of maple. It’s like taking care of a literal baby because she is one. 🍼🥹
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Gross poop update
I sent in a fecal test for maple bc her poops aren’t formed they’re liquidy. It came back positive for coccidia parasites, which is an intestinal tract infection.
So we will be taking her to the vet this Saturday to get treated.
She might be able to get over it on her own since she’s still really active and looks healthy but I don’t want to risk it.
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nurtiblend · 9 months
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The Gut Microbiome: How Your Gut Impacts Overall Health and Wellbeing
Unraveling the Complex World of Gut Microorganisms and Their Influence on Your Body and Mind
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The gut microbiome is a vast and intricate ecosystem of microorganisms residing in your digestive system, profoundly impacting your overall health and wellbeing. In this enlightening guide, we'll delve into the wonders of the gut microbiome and understand how it influences your body and mind in remarkable ways.
Understanding the Gut Microbiome
The gut microbiome is a vast and complex ecosystem of microorganisms that reside in our gastrointestinal tract, primarily in the large intestine. It consists of trillions of bacteria, viruses, fungi, and other microbes. This diverse community plays a crucial role in maintaining the health of the gut and influencing overall well-being.
Key Roles of the Gut Microbiome:
Digestion and Nutrient Absorption: The gut microbiome helps break down certain complex carbohydrates and fiber that our body cannot digest on its own. As a result, it contributes to the production of short-chain fatty acids and vitamins, which can be absorbed and utilized by our bodies.
Immune System Support: A healthy gut microbiome interacts with the immune system, influencing its development and function. It helps the immune system distinguish between beneficial and harmful substances, contributing to a balanced and appropriate immune response.
Gut Barrier Integrity: The gut microbiome aids in maintaining the integrity of the gut barrier, a selective permeable layer that prevents harmful substances from entering the bloodstream while allowing the absorption of essential nutrients.
Protection Against Pathogens: A diverse and balanced gut microbiome can help protect against harmful pathogens by crowding them out and producing substances that inhibit their growth.
Metabolism and Weight Regulation: Emerging research suggests that the gut microbiome may play a role in metabolism and weight regulation by influencing how our bodies extract energy from food.
Factors Influencing the Gut Microbiome:
Diet: The types of foods we eat can significantly impact the composition and diversity of the gut microbiome. A diet rich in fiber from fruits, vegetables, and whole grains promotes a diverse and healthy gut microbiome.
Antibiotics and Medications: The use of antibiotics and certain medications can disrupt the balance of the gut microbiome by affecting both beneficial and harmful bacteria.
Lifestyle: Factors such as stress, sleep patterns, and physical activity can influence the gut microbiome.
Age: The gut microbiome evolves throughout life, with significant changes occurring during early development and as we age.
Environmental Exposures: Environmental factors, such as pollution and exposure to toxins, can impact the gut microbiome.
Maintaining a Healthy Gut Microbiome:
To support a healthy gut microbiome, consider the following:
Eat a Balanced Diet: Consume a diverse range of plant-based foods and limit processed and sugary foods.
Probiotics and Fermented Foods: Incorporate probiotics and fermented foods (e.g., yogurt, kefir, kimchi, sauerkraut) that contain beneficial live microorganisms.
Prebiotics: Include prebiotic-rich foods (e.g., onions, garlic, leeks, bananas, oats) that nourish beneficial gut bacteria.
Avoid Overuse of Antibiotics: Use antibiotics judiciously and only when necessary.
Manage Stress: Practice stress-reducing techniques like mindfulness, meditation, or yoga.
Stay Active: Regular physical activity can positively influence the gut microbiome.
Stay Hydrated: Drink plenty of water to support digestive health.
The Gut-Brain Axis: Your Second Brain
The gut-brain axis is a bidirectional communication network that connects the gut (gastrointestinal tract) with the brain and involves a complex interplay of neural, hormonal, and immune signaling pathways. This connection is so profound that the gut is often referred to as the "second brain." The gut and the brain are closely linked, and they continuously send signals and information to each other, influencing various aspects of our physical and mental well-being.
Key Aspects of the Gut-Brain Axis:
Vagus Nerve: The vagus nerve, one of the longest nerves in the body, plays a crucial role in the gut-brain communication. It carries signals between the gut and the brain, enabling them to interact and share information.
Neurotransmitters: The gut produces and contains an extensive array of neurotransmitters, including serotonin, dopamine, and gamma-aminobutyric acid (GABA). These neurotransmitters also exist in the brain and are involved in regulating mood, emotions, and cognitive function.
Gut Microbiome: The gut microbiome influences the gut-brain axis by producing various compounds, such as short-chain fatty acids and neurotransmitters. These compounds can impact brain function and mood.
Immune System: The gut houses a large portion of the body's immune cells. Immune signaling molecules can communicate with the brain, affecting mood and mental health.
Impact on Mood and Emotions:
The gut-brain axis has a significant impact on mood and emotional well-being. For example:
Serotonin Production: Approximately 95% of serotonin, a neurotransmitter associated with mood regulation and feelings of well-being, is produced in the gut. The gut microbiome plays a role in serotonin synthesis.
Stress Response: The gut can respond to stress and emotional cues, which can influence digestive function and vice versa. Chronic stress can affect gut health and lead to gastrointestinal symptoms.
Anxiety and Depression: An imbalanced gut microbiome and gut inflammation have been linked to an increased risk of anxiety and depression.
Gut Sensation: The gut can sense emotions and stress, leading to sensations like "butterflies in the stomach" during anxious moments.
Gut Dysbiosis and Mental Health: Imbalances in the gut microbiome (dysbiosis) have been associated with various mental health disorders, including anxiety, depression, and even neurodevelopmental conditions like autism.
The Gut-Brain Axis and Mental Health:
Emerging research suggests that the gut-brain axis may have implications for mental health treatment and management. Certain interventions, such as probiotics and dietary changes that promote a healthy gut microbiome, have shown promise in alleviating symptoms of depression and anxiety.
However, it's essential to recognize that the gut-brain axis is a complex and dynamic system, and more research is needed to fully understand its intricacies. Lifestyle factors such as diet, stress management, sleep, and physical activity can influence the gut-brain axis and overall mental well-being.
Taking care of your gut health through a balanced diet, regular exercise, stress reduction techniques, and adequate sleep can contribute to maintaining a healthy gut-brain axis. If you experience significant mood disturbances or mental health challenges, seeking professional advice from a healthcare provider or mental health specialist is crucial for proper evaluation and support.
Impact on Digestive Health
The gut microbiome plays a vital role in digestion and nutrient absorption, influencing various aspects of digestive health. A balanced and diverse gut microbiome promotes efficient digestion and nutrient extraction, while an imbalanced microbiome can lead to gut-related issues.
Key Roles of the Gut Microbiome in Digestion:
Breaking Down Complex Carbohydrates: Certain gut bacteria have the enzymes required to break down complex carbohydrates, such as fiber and resistant starch, that our body cannot digest on its own. This process produces short-chain fatty acids, which serve as an energy source for the gut cells and support gut health.
Fermentation: The gut microbiome ferments undigested carbohydrates, producing gases and other byproducts. While excessive gas can be uncomfortable, moderate fermentation is essential for gut health.
Protein Digestion: Some gut bacteria help break down proteins into amino acids, which are the building blocks of various body tissues and play essential roles in bodily functions.
Nutrient Absorption: The gut microbiome is involved in the absorption of certain nutrients, such as vitamins B and K, which are produced by specific gut bacteria and are essential for various bodily functions.
Impact on Gut-Related Issues:
Gut Dysbiosis: Gut dysbiosis refers to an imbalance in the gut microbiome, where there is an overgrowth of harmful bacteria or a reduction in beneficial bacteria. Gut dysbiosis has been associated with various digestive issues, such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and chronic constipation.
Irritable Bowel Syndrome (IBS): IBS is a common digestive disorder characterized by symptoms like abdominal pain, bloating, gas, and changes in bowel habits. Studies have shown that alterations in the gut microbiome can contribute to IBS symptoms.
Inflammatory Bowel Disease (IBD): IBD includes conditions like Crohn's disease and ulcerative colitis, which are characterized by chronic inflammation of the gastrointestinal tract. Changes in the gut microbiome have been linked to the development and progression of IBD.
Constipation and Diarrhea: An imbalanced gut microbiome can influence bowel movements, leading to either constipation or diarrhea.
Gastrointestinal Infections: A healthy gut microbiome acts as a protective barrier against harmful pathogens, reducing the risk of gastrointestinal infections.
Gut-Brain Axis and Digestive Health: As mentioned earlier, the gut-brain axis plays a role in digestion. Stress and anxiety can negatively impact gut function and contribute to digestive issues.
Maintaining a Healthy Gut Microbiome for Digestive Health:
To promote digestive health and support a healthy gut microbiome:
Eat a Balanced Diet: Consume a diet rich in fruits, vegetables, whole grains, and probiotic-rich foods to nourish beneficial gut bacteria.
Limit Processed Foods and Added Sugars: Excessive consumption of processed foods and added sugars can negatively affect the gut microbiome.
Include Fermented Foods: Incorporate fermented foods like yogurt, kefir, sauerkraut, and kimchi to introduce beneficial live microorganisms.
Stay Hydrated: Drink plenty of water to support digestion and overall gut health.
Manage Stress: Practice stress-reduction techniques to support a healthy gut-brain axis.
Avoid Overuse of Antibiotics: Use antibiotics judiciously and only when necessary to minimize disruption of the gut microbiome.
Seek Professional Guidance: If you experience persistent digestive issues, consult with a healthcare provider or a registered dietitian to identify potential imbalances in the gut microbiome and receive personalized recommendations.
Immune System Guardians
The gut microbiome and the immune system have a close and intricate relationship, working together as immune system guardians to defend the body against infections and maintain immune balance. The gut is home to a vast community of microorganisms, including bacteria, viruses, fungi, and other microbes collectively known as the gut microbiota. These microorganisms interact with the immune system in several essential ways:
Immune Development: During early life, interactions between the gut microbiome and the immune system play a crucial role in the proper development and maturation of the immune system. This process helps the immune system distinguish between harmless substances and potentially harmful pathogens.
Gut Barrier Function: The gut lining serves as a physical barrier between the gut contents and the rest of the body. A healthy gut microbiome contributes to the maintenance of this barrier, preventing harmful bacteria and toxins from entering the bloodstream and causing infections.
Immune Response Regulation: The gut microbiome helps regulate the immune response, ensuring that it responds appropriately to threats while avoiding unnecessary inflammation. This balance is essential for preventing autoimmune conditions where the immune system attacks the body's own tissues.
Pathogen Defense: Beneficial gut bacteria help prevent the growth and colonization of harmful pathogens by competing for space and nutrients in the gut. Some gut microbes also produce antimicrobial substances that can directly inhibit the growth of pathogens.
Training the Immune System: The gut microbiome "educates" the immune system, teaching it to recognize harmless substances and developing tolerance to them. This process is crucial for preventing allergies and food intolerances.
Production of Immune-Regulating Molecules: Certain gut bacteria produce molecules that influence immune cell function and contribute to immune regulation.
Influencing Systemic Immunity: The gut microbiome's influence on the immune system extends beyond the gut. The microbiome can impact systemic immunity, affecting the body's response to infections and diseases.
The Importance of a Diverse Gut Microbiome:
A diverse and balanced gut microbiome is essential for optimal immune function. A variety of beneficial bacteria can perform different functions, enhancing the gut's defense capabilities and promoting immune system balance. Factors such as diet, antibiotics use, stress, and lifestyle choices can impact the diversity and composition of the gut microbiome.
Supporting Gut Microbiome and Immune Health:
To maintain a healthy gut microbiome and support immune health:
Eat a Balanced Diet: Consume a diet rich in fiber, whole grains, fruits, and vegetables to nourish beneficial gut bacteria.
Include Fermented Foods: Incorporate probiotic-rich fermented foods like yogurt, kefir, kimchi, and sauerkraut to introduce beneficial live bacteria.
Limit Use of Antibiotics: Use antibiotics judiciously and only when necessary, as they can disrupt the gut microbiome.
Manage Stress: Practice stress-reduction techniques, as chronic stress can impact the gut microbiome and immune function.
Stay Active: Regular physical activity can positively influence the gut microbiome and immune system.
Prioritize Sleep: Aim for sufficient and restorative sleep, as inadequate sleep can affect the gut microbiome and immune function.
Avoid Excessive Hygiene: Overuse of antibacterial products may disrupt the natural balance of the gut microbiome.
Influence on Weight and Metabolism
The gut microbiome has a significant influence on body weight, metabolism, and obesity. Research has shown that the composition and function of the gut microbiota can impact how our bodies store and metabolize energy from food. Several ways in which the gut microbiome affects weight management are:
Energy Harvesting: Certain gut bacteria are efficient at extracting energy from food, particularly from complex carbohydrates and dietary fibers that our body cannot digest on its own. When these bacteria break down these compounds, they produce short-chain fatty acids (SCFAs), which can be absorbed and used as an energy source. This energy harvesting can contribute to weight gain if the excess energy is stored as fat.
Regulation of Fat Storage: The gut microbiome plays a role in regulating how our bodies store fat. Imbalances in the gut microbiota have been associated with increased fat storage and obesity.
Appetite Regulation: The gut microbiome can influence the production of hormones that regulate appetite, such as leptin and ghrelin. An imbalanced gut microbiome may lead to hormonal disruptions, potentially leading to overeating and weight gain.
Inflammation and Insulin Resistance: An unhealthy gut microbiome can promote low-grade inflammation and insulin resistance, both of which are associated with obesity and metabolic disorders.
Impact on Metabolism: The gut microbiome can affect the metabolism of various nutrients, including fats and carbohydrates. An imbalanced gut microbiome may alter how these nutrients are processed, potentially contributing to weight gain.
Influence of Short-Chain Fatty Acids (SCFAs): SCFAs produced by certain gut bacteria have been linked to improved metabolic health and reduced risk of obesity. They can also play a role in maintaining gut barrier integrity and reducing inflammation.
Gut Microbiome and Weight Gain:
Studies have shown that the gut microbiome of obese individuals is often different from that of lean individuals. Obese individuals tend to have a less diverse gut microbiome and a higher abundance of certain bacteria that are associated with weight gain.
Gut Microbiome and Weight Loss:
Research has also explored the relationship between the gut microbiome and weight loss. Some studies suggest that certain gut bacteria may support weight loss, particularly when following a healthy diet and lifestyle changes. When individuals lose weight through diet and exercise, the composition of their gut microbiome can change, potentially promoting a healthier microbiome profile.
Implications for Obesity Management:
While the gut microbiome's role in weight management is still being studied, it holds promise for potential therapeutic interventions for obesity. Strategies to modulate the gut microbiome, such as the use of probiotics, prebiotics, and personalized dietary interventions, are being explored as potential tools for obesity management.
Fermentation and Short-Chain Fatty Acids
Fermentation is a crucial process that occurs in the gut, involving the breakdown of certain dietary components by beneficial gut bacteria. During fermentation, these gut bacteria metabolize complex carbohydrates and fibers that are not fully digested in the upper digestive tract. As a result, fermentation leads to the production of various beneficial compounds, including short-chain fatty acids (SCFAs).
Short-chain fatty acids are a group of fatty acids with relatively short carbon chain lengths, typically containing fewer than six carbon atoms. The three main SCFAs produced during fermentation in the gut are:
Acetate: Acetate is the most abundant SCFA in the gut. It can be absorbed into the bloodstream and transported to different organs, where it serves as an energy source.
Propionate: Propionate is another important SCFA that is absorbed and taken to the liver. In the liver, propionate has various metabolic effects and may influence glucose metabolism.
Butyrate: Butyrate is a key SCFA that has numerous health benefits. It serves as a primary energy source for the cells lining the colon and plays a critical role in maintaining gut health. Butyrate also has anti-inflammatory properties and supports a healthy gut barrier function.
Health Benefits of Short-Chain Fatty Acids:
The production of SCFAs through fermentation in the gut offers several health benefits:
Gut Health: SCFAs, particularly butyrate, play a vital role in maintaining the health and integrity of the gut lining. They promote the growth of beneficial gut bacteria, reduce inflammation, and help prevent gut permeability or "leaky gut."
Immune Support: SCFAs can influence immune cell function and promote a balanced immune response, helping to defend against infections and regulate immune-related conditions.
Anti-Inflammatory Effects: Butyrate and other SCFAs have anti-inflammatory properties that can help reduce chronic low-grade inflammation, which is associated with various chronic diseases.
Metabolic Health: SCFAs, especially propionate, may influence metabolic processes, including glucose metabolism. They can potentially support blood sugar regulation and insulin sensitivity.
Weight Management: Some research suggests that SCFAs may influence appetite regulation and energy balance, potentially playing a role in weight management.
Sources of Fermentable Substrates:
Fermentable substrates are the complex carbohydrates and dietary fibers that gut bacteria ferment to produce SCFAs. Some common sources of fermentable substrates include:
Dietary fibers from fruits, vegetables, legumes, and whole grains
Resistant starch found in certain cooked and cooled foods like potatoes and rice
Oligosaccharides from foods like beans and lentils
Pectin from fruits like apples and citrus fruits
Inulin and fructooligosaccharides (FOS) from foods like onions, garlic, and bananas
A diet rich in these fermentable substrates can support a diverse and healthy gut microbiome, leading to the production of beneficial SCFAs and contributing to overall gut and metabolic health. Incorporating a variety of plant-based foods in the diet is a great way to ensure an adequate supply of fermentable substrates for gut health.
Diet and the Gut Microbiome
Your diet plays a fundamental role in shaping the composition and diversity of your gut microbiome. Different dietary components act as substrates for various gut bacteria, influencing their growth and metabolism. A diet rich in diverse plant-based foods can support a thriving gut ecosystem and promote a balanced and beneficial gut microbiome. Here are some ways in which your diet impacts the gut microbiome:
Fiber Intake: Dietary fibers, found in fruits, vegetables, whole grains, legumes, and nuts, are a primary food source for many beneficial gut bacteria. These fibers are fermentable, meaning they can be broken down by gut bacteria during fermentation, leading to the production of SCFAs and other beneficial metabolites. High-fiber diets promote the growth of SCFA-producing bacteria, which contributes to gut health and supports a diverse gut microbiome.
Plant-Based Foods: A diet rich in a wide variety of plant-based foods introduces a broad range of nutrients and phytochemicals that nourish different types of gut bacteria. Plant-based diets are associated with greater gut microbiome diversity, which is generally linked to better health outcomes.
Probiotic and Fermented Foods: Probiotic-rich foods, such as yogurt, kefir, kimchi, sauerkraut, miso, and tempeh, contain live beneficial bacteria that can directly influence the gut microbiome when consumed. Fermented foods can introduce beneficial bacteria and potentially help improve gut microbial diversity.
Prebiotic Foods: Prebiotics are non-digestible fibers that serve as food for beneficial gut bacteria. Foods rich in prebiotics include garlic, onions, leeks, asparagus, chicory root, and dandelion greens. Consuming prebiotic-rich foods supports the growth of beneficial gut bacteria.
Avoiding Excessive Sugar and Processed Foods: Diets high in added sugars and processed foods can lead to imbalances in the gut microbiome. These types of diets may promote the growth of harmful bacteria and reduce the abundance of beneficial ones.
Adequate Hydration: Staying hydrated is essential for overall health, including gut health. Drinking enough water supports regular bowel movements and a healthy gut environment.
Polyphenol-Rich Foods: Foods rich in polyphenols, such as berries, cocoa, green tea, and olive oil, have antioxidant and anti-inflammatory properties that can positively influence the gut microbiome.
Remember that the gut microbiome is highly individualized, and the impact of diet can vary from person to person. Genetics, age, lifestyle, and other factors also play a role in shaping the gut microbiome.
Probiotics and Prebiotics: Cultivating Gut Health
Probiotics are live beneficial microorganisms that, when consumed in adequate amounts, can confer health benefits to the host. They can help balance the gut microbiome by introducing beneficial bacteria. Probiotic-rich foods include yogurt, kefir, kimchi, sauerkraut, miso, and tempeh. Additionally, probiotic supplements are available for targeted probiotic intake.
Prebiotics, on the other hand, are non-digestible fibers that serve as food for beneficial gut bacteria. They help promote the growth and activity of these beneficial bacteria. Foods rich in prebiotics include garlic, onions, leeks, asparagus, chicory root, and dandelion greens.
Combining probiotics and prebiotics in the diet can create a synergistic effect known as synbiotics, promoting the growth and survival of beneficial gut bacteria.
Factors Influencing Gut Health
Several lifestyle factors can influence the balance of the gut microbiome:
Stress: Chronic stress can disrupt the gut microbiome, leading to an imbalance of gut bacteria. Managing stress through relaxation techniques like meditation or deep breathing can support gut health.
Sleep: Poor sleep quality and insufficient sleep have been linked to alterations in gut microbial composition. Prioritizing good sleep hygiene can positively impact the gut microbiome.
Exercise: Regular physical activity has been associated with a more diverse and beneficial gut microbiome. Engaging in moderate exercise can contribute to a healthier gut environment.
Medications: Certain medications, particularly antibiotics, can disrupt the gut microbiome by affecting both beneficial and harmful bacteria. When prescribed antibiotics, it's essential to follow the healthcare provider's instructions and consider probiotic supplementation if necessary.
Gut Health and Chronic Conditions
Research suggests that the gut microbiome plays a role in various chronic conditions:
Autoimmune Diseases: Imbalances in the gut microbiome have been linked to autoimmune diseases like rheumatoid arthritis, multiple sclerosis, and inflammatory bowel disease.
Allergies: The gut microbiome's composition in early life may influence the development of allergies and allergic diseases.
Mental Health: The gut-brain axis connects the gut and the brain, and disruptions in the gut microbiome have been associated with certain mental disorders, such as depression and anxiety.
Nurturing a Healthy Gut: Lifestyle Tips
To foster a healthy gut microbiome, consider these lifestyle tips:
Balanced Diet: Consume a diverse and balanced diet rich in fiber from fruits, vegetables, whole grains, and legumes to support beneficial gut bacteria.
Probiotic and Prebiotic Foods: Incorporate probiotic-rich foods and prebiotic-rich foods into your diet for a healthy gut environment.
Reduce Stress: Practice stress-reduction techniques, such as mindfulness, yoga, or spending time in nature, to support gut health.
Prioritize Sleep: Aim for 7-9 hours of quality sleep per night to support a healthy gut microbiome.
Moderate Exercise: Engage in regular moderate exercise to promote a diverse gut microbiome.
Minimize Antibiotic Use: Use antibiotics only when necessary, and consider probiotic supplementation during and after antibiotic treatment.
Limit Processed Foods: Reduce the intake of highly processed and sugary foods, which may negatively impact gut health.
By prioritizing these lifestyle factors, you can cultivate a flourishing gut microbiome and support overall well-being. Remember that individual responses to dietary and lifestyle changes can vary, so it's essential to find what works best for you and consult with a healthcare professional if needed.
Your gut microbiome plays a pivotal role in shaping your health, immunity, and even your emotional well-being. Embrace the marvels of the gut microbiome and cultivate a thriving ecosystem through mindful dietary choices, lifestyle habits, and proactive measures. Prioritizing gut health can unlock a world of benefits, contributing to your overall vitality and wellbeing. Listen to your gut and nourish it wisely—it's the key to a healthier and happier you.
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bpod-bpod · 1 year
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Too Small Intestines
The rarity of some genetic disorders can make them difficult to study in patients. An animal model that replicates some of the disease mechanisms can help researchers, and a new study has developed the first zebrafish model for Feingold syndrome type 1, which causes incomplete development of the gastrointestinal tract among other symptoms. The condition is caused by mutations in the gene Mycn (stained green, active throughout the intestines of healthy fish, pictured). The mutant fish developed short intestines with reduced folding, and the deletion of Mycn impacted other genes as well, including those in a central regulator of protein synthesis, the mTOR signalling pathway. Supplementation with leucine, a building block that activates the mTOR pathway, helped restart protein synthesis and led to a partial recovery of intestine size. If the mechanisms translate to human biology, this simple supplement could bring relief to patients with Feingold syndrome type 1.
Written by Anthony Lewis
Image from work by Yun-Fei Li, Tao Cheng and colleagues
Zhejiang University School of Medicine, Hangzhou, China
Image originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)
Published in PLOS Biology, November 2022
You can also follow BPoD on Instagram, Twitter and Facebook
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usfreehealthcare · 11 months
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natural remedy for gastroparesis
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Gastroparesis or stomach paralysis is a condition in which the movement of the stomach (due to spontaneous muscle contraction) does not work properly. When the stomach muscles are strong and healthy, they push food forward along the digestive tract in preparation for release into the intestines.   In gastroparesis, this mobility is limited or absent at all, and therefore the contents of the stomach are not emptied completely. In this way, the natural digestion process is disrupted and the conditions for symptoms such as nausea, vomiting, increased blood sugar, etc. are provided.   Currently, there is no definitive treatment for this problem and only the symptoms can be improved. We recommend to start with home treatment of stomach paralysis and traditional medicine. If they are not effective, go to drug therapy. Because most home remedies are safe and without side effects.
Treatment of gastroparesis with home and natural methods
According to statistics, the probability of contracting gastric paralysis is about 50 cases per 100,000 people. Women are 4 times more prone to this problem than men. Although experience has shown that home remedies are really effective in managing gastroparesis, it is very important to seek medical advice from a gastroenterologist and a neurologist. Because the complications of this disease, such as dehydration, malnutrition, and blood sugar fluctuations, can negatively affect the overall quality of life. In the following, we will mention the most important home remedies for stomach paralysis. Change in eating habits Here are some tips on how to eat that you can pay attention to in order to improve the condition and reduce the symptoms of gastroparesis. Things like: Eating smaller meals Eating smaller meals in several sessions will make your stomach completely empty and reduce bloating. Proper chewing of food the more food is chewed, the easier it is digested in the stomach. So, spend time chewing your food properly to help with digestion. Avoid lying down during and after eating When you lie down after eating, you stop the digestion process and slow down the digestion, because digestion needs gravity to function properly. In addition, lying down after a meal also helps the reflux of stomach acid into the esophagus. Drink fluids between meals Avoid drinking fluids with meals, as they take up space in the stomach and can slow digestion and cause bloating. Instead, drink fluids between meals to stay hydrated. Regular practice of yoga Yoga has been found to stimulate the normal function of the liver and pancreas to regulate blood sugar levels. As a result, if the blood sugar level increases or decreases, it can improve the symptoms of gastroparesis. On the other hand, it has been found that performing abdominal exercises and yoga breathing exercises are useful as a means to better control gastroparesis. To do them, place one hand on your stomach and the other hand on your chest and focus on your breathing with your eyes closed. Inhale and exhale slowly through your nose and sometimes try to pinch your nose and tilt your chin to let all the air out. Slow down your breathing while concentrating. Another movement is to rotate the spine while sitting on a chair. Place one arm behind the chair and look behind you while inhaling and exhaling slowly through your nose. Return to center and do the same for the other arm. Another movement is to bring your arms towards your back with the help of interlaced fingers and extend them until the chest opens and the ribs are pushed out. Make sure to keep your attention on your breath in this situation. Daily use of aloe vera for home treatment of stomach paralysis Aloe vera helps the process of digestion and regulating bowel movement. In fact, as a natural laxative, it is effective in supporting the proper functioning of digestion and relieves bloating and stomach pain. We recommend that you take a cup of aloe vera juice every morning before defecation for the home treatment of stomach paralysis. You can make this mixture by mixing two tablespoons of aloe vera gel with a cup of water or orange juice in a blender. Before meals, you can drink aloe vera juice. Avoid consuming more than two tablespoons of aloe vera gel per day. Add apple cider vinegar to your diet Apple cider vinegar helps to alkalize the body, which is effective in improving stomach pain, heartburn and bloating and improving the digestion process. Dissolving a teaspoon of apple cider vinegar in a cup of warm water and consuming it 15 to 20 minutes before meals is all you need to improve the symptoms and home remedies for gastric paralysis. Avoid undiluted apple cider vinegar, as it is too acidic and can damage your teeth. Stomach paralysis diet Paying attention to diet is another key measure that can help improve gastroparesis. In fact, knowing what to eat and what to avoid is important. In the following, we will refer to the complete details of the diet of gastric paralysis patients. Suitable foods in gastroparesis diet Common foods include fruits and vegetables in the form of purees and smoothies, canned peaches and pears, well-cooked fruits and vegetables, juices and soups. Because in the condition of stomach paralysis, the stomach does not have the power to digest well and we have to help this problem by chopping or heating the food. Of course, consulting a nutritionist can help you determine more suitable foods. You should be careful with your fiber intake, because its increase in gastric paralysis can cause constipation and bloating. Therefore, consumption of low-fiber foods is recommended. Try to eat more carbohydrates and starches such as corn tortillas, cookies, toasted grains, sweet potatoes (without the skin) and white or refined bread, crackers, bagels, pasta or rice. To provide protein and calcium, low-fat cheese, custard, boiled eggs, minced or pureed meat, low-fat milk and milkshakes, plain yogurt and frozen yogurt, skinless chicken, oysters, tofu, and fish. Tons are great. When following a gastroparesis diet, it is best to go for coconut oil, as it contains essential fatty chains that can aid in digestion. In general, it's important to eat softer foods because they're easier to digest and put less stress on your digestive system. This issue is more important in following the gastric paralysis diet for children. Prohibited foods in the gastroparesis diet Experience has shown that avoiding certain foods can help reduce symptoms because they are difficult for the digestive system to digest. To begin with, it is better to know that fatty and trans-containing foods delay gastric emptying. On the other hand, choosing the right fats such as unsaturated fats can help digestion. So be aware of the types of fats you consume. As mentioned, consuming too much fiber can make symptoms worse, so low-fiber foods are a better option. High-fiber foods include fruits such as apples, berries, figs and oranges, vegetables such as broccoli, cauliflower, green beans, whole grains, nuts and seeds, beans and lentils. Also, avoid eating foods that are not easily chewed, because they are harder to break down through the digestive process. These consist of corn, seeds, and nuts. Avoid eating unhealthy foods such as fast food because they can cause blood sugar levels to fluctuate. Finally, cut back on alcohol as it significantly slows down gastric emptying. Treatment of gastroparesis in traditional medicine In addition to emphasizing the points mentioned about diet in gastroparesis or delayed gastric emptying, traditional medicine experts also emphasize the use of ginger as an anti-nausea herbal medicine. Drinking peppermint or chamomile tea may also be helpful. On the other hand, placing a warm pad on the abdomen or a warm water bath may also help reduce abdominal pain associated with gastroparesis. Recently, traditional medicine has been able to prove the beneficial effects of acupuncture and acupressure for the treatment of gastric paralysis. In fact, these alternative solutions use the manipulation of trigger points on the body, either with pressure or with needles, to treat gastric paralysis with traditional medicine. Some studies have also been able to show relief of bloating and other digestive symptoms in patients who have done acupressure or acupuncture. Usually, the wrist, forefoot and under the kneecap are the most effective trigger points for the treatment of gastric paralysis in traditional medicine. Always talk to a traditional medicine practitioner before doing acupressure or acupuncture, as they know more about the key areas of the body to heal stomach and digestive problems. When should we see a doctor? We recommend that you see a doctor or traditional medicine specialist as soon as you experience the symptoms of stomach paralysis. Because any delay increases the possibility of complications of this disease. Read the full article
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trylkstopocket · 1 year
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4 strategies to stop blood sugar swings and avoid that afternoon crash
Unless you have diabetes, you probably don’t give much thought to how your blood sugar changes throughout the day. You’d be wise to pay more attention: While some fluctuation is normal, many people experience major spikes and dips, which can sap your energy, derail your focus, and lead to weight gain, says Grace Derocha, MBA, RDN, CDCES, a dietitian and spokesperson for the Academy of Nutrition and Dietetics who specializes in workplace wellness.
Perhaps even more concerning is the fact that high glucose variability—meaning you have a significant gap between your highs and lows—has been tied to an increased risk of insulin resistance, or the inability to use insulin efficiently, which often paves the way for type 2 diabetes. Wide glucose variability may also increase your odds of having heart attack or stroke, according to a 2020 study published in Cardiovascular Diabetology. 
How to get off the rollercoaster? For otherwise healthy people (who don’t have diabetes), it largely comes down to making some key lifestyle changes, starting with what you eat. These four smart strategies can help even out your blood sugar so you feel better and stay healthier.
1. Watch out for surprising sources of sugar
You likely know that candy, pastries, and heavily-sweetened drinks (including soft drinks and various coffee concoctions) can all send your blood sugar soaring. But anything carb-heavy, even if it doesn’t contain added sugar or taste sweet, has the potential to cause a similar effect. Watch out for refined (white) breads and highly processed cereals, which are easy to overdo.
Bottled salad dressings and condiments like ketchup and barbeque sauce also often pack a surprising amount of added sugar, as do many plant-based milk alternatives. Be sure to read labels, and pick accordingly—especially if you tend to drown your salad and like your coffee extra light, warns Derocha.
Fruit is another potential offender, especially if you choose the dried variety or super-size your servings. “One of those little boxes of raisins is probably equal to 15-20 regular grapes” as far as (natural) sugar content is concerned, says Derocha.
Whole fruit is generally a better bet, but that doesn’t mean you should eat unlimited amounts when it comes to higher-sugar options like grapes, bananas, watermelon, and mango. “People think, ‘It’s fruit and it’s healthy for me, because it has a lot of fiber and vitamins,’ and that’s true,” she says. “But I had a patient that used to freeze grapes and eat the whole bag.” 
2. Eat fiber first
It might sound gimmicky, but there’s good evidence that simply changing the order in which you eat your food makes a big difference in terms of the impact it has on your blood sugar, says Jessie Inchauspé, a biochemist who studies the effect of food on health. Even if you don’t change the components of a meal—say, pasta, chicken, and vegetables—eating the vegetables first, followed by the protein and finally the carbs—can cut the resulting glucose spike substantially.
“We often talk about what to eat or not eat, but this is about how,” she explains, echoing advice shared in her new book, Glucose Revolution, and on her popular Instagram page. She points to several studies, including a 2018 research from the Journal of Nutritional Science and Vitaminology in which subjects were instructed to eat the same meal of rice, vegetables, and meat after an overnight fast on different days; when eating rice last, glucose and insulin levels were significantly lower 30 minutes after the meal than they were when they ate the rice first.
Fiber, Inchauspé explains, coats the upper intestines and creates a mesh that prevents the body from absorbing too much glucose from the rest of the meal. Protein and fat also help slow movement of food through the gastrointestinal tract, so by the time the carbohydrates enter the body they don’t flood the bloodstream with glucose as dramatically.
For bonus points, she advocates starting meals with an additional vegetable dish, such as a salad, and drizzling on some vinegar: “It can curb a glucose spike from a subsequent meal by up to 30%, because the acetic acid in the vinegar slows the breakdown of starches into glucose,” she says. “It also goes into the muscles and tells them to soak up more glucose” from the bloodstream.
“I was actually shocked when I learned this about vinegar,” she says, but “clinical trials have shown how it can impact your health from a glucose perspective.”
3. Be carb-consistent throughout the day
Going low-carb at breakfast and lunch for the express purpose of splurging at dinner doesn’t work if your goal is to keep your blood sugar steady. “You can’t bank carbs,” says Derocha. The best way to keep your blood sugar on an even keel is to have a similar amount of carbohydrates during each of your three meals (or, if you prefer, five mini meals).
On a similar note, while a sweet treat might seem most appealing mid-afternoon or late at night, the best time to give into that ice cream or cookie craving is actually right after you’ve finished eating a meal that contains some protein, fat, and fiber. Not only will you eat less of the treat,, but the other nutrients you just consumed will help blunt the impact on your blood glucose level and the impact won’t be as great as if you indulged on an empty stomach. For the same reason, consider starting your day with a savory (rather than sweet) breakfast, says Inchauspé.
4. Move after meals
To avoid a major post-meal blood sugar spike, resist the urge to lounge on the couch after dinner. Instead, do something moderately active for at least 10 minutes, says Inchauspé. The goal is to activate your muscles so they’ll seek out glucose from your bloodstream and utilize it rather than letting it linger there.
Indeed, numerous studies support the importance of moving after meals, including a 2021 meta-analysis published in the journal Sports Medicine; the authors concluded that 30 minutes of aerobic activity in the postprandial state is ideal for decreasing glucose and insulin levels in healthy adults. Derocha also points to research that found people with fasting blood sugar readings in the prediabetic range were able to modulate their high blood sugar simply by walking for 15-minutes three times a day (after each meal). “Even just cleaning up the dishes or folding laundry will provide some movement that helps lower blood sugar,” she says.
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puppyexpressions · 1 year
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Thanksgiving Foods Your Dog Can and Can’t Eat
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Thanksgiving is a time to celebrate and spend time with friends and family. For many people, this also includes the family dog, but which traditional holiday foods are safe for Fido to snack on and which are a big no-no? Here are pooch-approved foods—what you can (and can’t) feed dogs from the family feast.
Foods That Dogs Can Eat
What morsels can you slip your pup as a treat to celebrate the season? Dog-friendly human foods include…
Apples: A great source of fiber and vitamins A and C, apples are a fantastic, tasty treat for any pooch. While your dog will thank you for a few apple slices, never give it the core or seeds, which can be toxic in sufficient quantities.
Bread: As long as your dog doesn’t have an allergy to wheat, plain white or wheat baked bread—that is, without any nuts, seeds, raisins, or spices—is fine as an occasional snack in small amounts, but don’t overdo it. Dogs don’t derive any nutritional benefit from bread and, as with humans, too much can pack on the pounds. Avoid bread with artificial sweeteners or lots of salt and never feed your dog raw (unbaked) bread dough. 
Carrots and celery: While you’re preparing the Thanksgiving stuffing, slip your furry friend some spare carrots and/or celery, both of which are low in calories and full of nutrients and vitamins and can even have benefits for oral health. Cut into bite-size pieces to make them easier to digest and to prevent choking.
Cheese: Unless your pooch is lactose-intolerant, cheese is a good choice for an occasional treat, especially if you stick to lower fat varieties like mozzarella. Low- or nonfat cottage cheese is also a great option.
Corn: A common ingredient in many dog foods, corn kernels are perfectly healthy for your dog in small amounts. Don’t ever give them the cob, which can cause choking or intestinal blockages if swallowed.
Green beans: Before you make Homemade Green Bean Casserole for the Thanksgiving meal, you can feel good about giving a few green beans to your dog as a healthy treat. Stick to raw or cooked plain green beans cut into bite-size pieces. Stay away from canned beans with added salt or spices or beans cooked with oils, spices, or other ingredients that aren’t dog-friendly.
Pumpkin: Plain, canned, puréed pumpkin is a good treat that’s gentle on the digestive system. Never give your dog spiced pumpkin pie mixes.
Rice: As long as your dog isn’t allergic to rice or diabetic, cooked white rice is perfectly safe moderation. Avoid brown rice, which is harder to digest.
Turkey: Good news! The star of most Thanksgiving dinners is perfectly safe for dogs, in general—if it is plain, unseasoned, properly cooked, and given in small amounts. White meat is best, as it contains less fat, fewer calories, and more protein. Before preparing a plate for your pooch, be sure to remove any fat or skin and never, ever give them the bones, which can splinter and cause tears or blockages in the digestive tract. Avoid giving your dog any seasoned or processed turkey, which may contain harmful ingredients.
Sweet potatoes: Are a great source of dietary fiber, vitamin B6, vitamin C, and beta-carotene. Sweet potato treats can be as simple as a dehydrated sweet potato chew. Just remember not to give your pet sweet potatoes containing any added ingredients.
Potatoes: You get to enjoy both kinds of potatoes, and your dog can have that option, too. However, give only boiled or baked potatoes with no butter, sour cream, salt, or pepper, and serve in moderation.
Plain peas: Are a fine choice, but creamed peas should be avoided. Fattier food items like creamed peas may upset your dog’s stomach.
Dessert is an option, but not just any kind. Go ahead and satisfy your pet’s sweet tooth with something healthy like frozen yogurt (without artificial sweeteners like xylitol, which is toxic for dogs). Calcium, protein, and live bacteria that can act as probiotics will give your dog a tasty dose of nutrients and a sweet post-meal treat.
Note: For those dogs with food allergies or other health conditions, please check with your vet first. Remember: Any new food might potentially cause digestive issues—introduce it to your dog in small amounts.
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Foods That Dogs Can’t Eat
It’s natural to want to share with our furry friends, but there are a lot of holiday drinks, dishes, and desserts that are definitely not dog-friendly. Stay away from:
Alcohol: Alcohol and animals don’t mix. Depending on the size of the dog, even small amounts can result in alcohol toxicity with symptoms that can include drooling, lethargy, weakness, and collapse. If you know that your dog has ingested anything with an alcohol content (even mouthwash!) or is showing any signs of alcohol toxicity, contact a vet immediately.
Chocolate: You’ve probably heard this before, but it bears repeating—Do not feed your dog chocolate. It’s highly toxic (especially the darker varieties) and can cause nausea, diarrhea, abnormal heart rate, seizure, and muscle tremors, among other symptoms. In rare cases, death can occur.
Coffee and tea: You might live for your morning cup of coffee, but dogs are much more sensitive to caffeine’s effects. While a little slurp of coffee or tea likely won’t cause any issues (especially in midsize or larger breeds), contact the vet if larger amounts, grounds, beans, or tea bags have been consumed.
Garlic, leeks, and onions: All parts of all members of the Allium family are highly toxic to dogs. Watch closely any dog that might have eaten a stray garlic clove or slice of onion for symptoms that can include decreased appetite, weakness, lethargy, and fainting. If you notice any of these signs of onion toxicity, contact a vet immediately.
Grapes and raisins: Grapes and their dehydrated cousins are highly toxic to dogs. Even small amounts can cause kidney failure.
Ice cream: As a general rule, dogs do not tolerate high- or full-fat dairy products well. To avoid any gastrointestinal distress but still reward your pup with a cold treat, skip the ice cream and feed them frozen fruit like blueberries, strawberries, and bananas. Another option is nondairy frozen treats specially formulated just for dogs.
Mashed Potatoes and Gravy: Packed with dairy and oh-so-delicious butter, this dish is 100% off limits. Heaping amounts of fat in this beloved side dish are likely to cause gastrointestinal (GI) upset at best—in the form of urgent diarrhea—or pancreatitis at worst.
Gravy is equally harmful and incredibly heavy in sodium and fat.
Because it’s so tasty and requires no chewing, this side dish would likely be lapped up in record time if you leave your plate unprotected. However, there’s a high probability of it coming back up while you’re enjoying your own holiday meal.
Raw yeast dough: While plain, baked bread is fine for your dog, never feed it raw (uncooked) yeast dough, which can cause severe life-threatening bloating. In addition, yeast can ferment in a dog’s digestive system and possibly cause ethanol (alcohol) poisoning.
Meat Fat, Bones and Skin: Turkey carcasses and fat drippings are perhaps a dog’s dream from heaven, but they can cause serious complications for your dog’s gastrointestinal tract.
Dogs should not be offered meat with bones, excess fat, skin or drippings, as these pose grave risk for conditions such as gastrointestinal blockage or injuries. They can also lead to more complex diseases like pancreatitis.
Casseroles and Spreads: While green bean casserole may sound like one of the healthier options on the table, the name is deceiving. Holiday casseroles like this one are laden with heavy creams, butter, oils and salt as well as garlic and onion—both of which are toxic to dogs. Even if a dish is based around a vegetable that is safe for dogs, such as green beans or sweet potatoes, when it falls into the casserole category, it is not one to share with your pup. 
Dogs should also not be given dairy products. Avoid the heavy appetizers, such as cheese balls and fatty dips and spreads. Most dogs do not tolerate dairy well, and the holidays are not an ideal time to test the limits of their GI tract.
Stuffing: Stuffing is a fatty, sodium-packed food that contains onions and garlic, which are both toxic to dogs.
Tips for Avoiding an Emergency Vet Trip
It may be the most wonderful time of the year, but you may find yourself making a trip to the emergency veterinarian if your dog indulges in foods from the table.
While there are some healthy holiday food options for dogs, always proceed with caution and only give a little at a time.
Remember, if your dog isn’t acclimated to a variety of foods, introducing multiple people foods at once can be overwhelming to their digestive system.
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stpauligirl · 2 years
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7. current obsession?
25. the story behind a scar of yours?
7. current obsession
under a cut because long
Dracula Daily! I get to have a mini book club almost every day, but with memes! I had read Dracula once before, but of course read it straight through in just a few sittings. I didn't stop to ponder what *exactly* the Count did to his victims. I didn't notice how bananas the dynamic is in the group we now affectionately refer to as the London Polycule. And of course without Tumblr I certainly would have overlooked some of the most hilarious details.
Like this, from the Oct 5 entry:
"A tall man, thin and pale, with high nose and teeth so white, and eyes that seem to be burning. That he be all in black, except that he have a hat of straw which suit not him or the time."
I just love that when describing the Count to someone else, the sailors fucking roasted him for his ugly straw hat. So out of fashion!
The last time I participated in a large-scale online book club was Infinite Summer, which was dedicated to reading the behemoth Infinite Jest. It wasn't nearly as fun.
25. the story behind a scar of mine
I was 24 years old and had been dating my now-husband for about 6 months, and he invited me to come home with him for Thanksgiving. Starting several days before that, however, I began to feel unwell. Throwing up and worse, bouts of shivering, and an overall pain in my midsection. I am generally a very healthy person (even more so at age 24) and assumed it was just some minor ailment that would go away like always. And I didn't want to cancel my holiday plans for a "tummy ache."
Well friends, things took a sharp turn for the worse while we were on the plane. Convulsive shivering and a pain in my guts so severe I couldn't stand up straight. I woke up early the next morning vomiting again. I went to the emergency room and had my appendix out right before Thanksgiving. Was discharged the next day, because America. And spent the rest of the holiday weekend recovering from surgery at the house of my future in-laws, and unable to eat solid food at a holiday gathering that is really only about the eating of food. I was horribly bloated as my intestinal tract was healing, plus I was on a high dose of opioid painkillers. WHAT A GREAT IMPRESSION YOUR GIRLFRIEND IS MAKING. I felt so awkward.
So anyway, they were able to perform the appendectomy laparoscopically, and I only have a teeny tiny scar that is conveniently located inside my belly button.
It is the only scar I have and is basically invisible.
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simplyarantxa · 1 year
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Probiotics for Diabetics
The term probiotic alludes to miniature organisms like bacteria and yeast that, when eaten, gainfully affect your health. Foods that contain useful bacteria, for example, 'live' yoghurts, are called 'probiotic'.
Ordinarily we take anti-infection agents to battle bacteria, so the possibility that you ought to ingest live bacteria appears to be a piece bizarre. Our bodies, however, are overflowing with bacteria, a large portion of which are useful. For sure, there are in excess of 500 kinds in our stomachs, helping our digestion and keeping our digestion tracts healthy.
What probiotics do
The issue, when you take anti-microbials to treat an infection, is that the anti-toxins eliminate the friendly bacteria (the ones that help digestion) alongside the bacteria that are causing the infection.
Thus, the equilibrium of good bacteria in the stomach is upset. As indicated by analysts, taking probiotics helps stimulate the friendly bacteria so your intestinal capabilities are gotten to the next level.
Probiotics additionally help to maintain the resistant system.
In social orders where cleanliness rehearses are good, as in the further developed nations, there has been a sharp expansion in immune system diseases (in which the safe system responds against the tissues of its own body) and hypersensitive diseases (in which the body has a strange response to substances that are usually innocuous).
The expansion in these diseases might be because under extremely clean circumstances the resistant system isn't tested by pathogenic organisms. In the perspective on clinical specialists, probiotics can prime and reinforce the resistant system.
Security and probiotics
The consensus among clinical scientists is that taking probiotics is protected and gives ascend to not many aftereffects. The main special cases are licenses with seriously debilitated resistant systems and extreme illnesses like pancreatitis.
For thousands of years individuals all around the world have been eating cheddar, yogurt and different foods containing live cultures. Thus it isn't is really to be expected that probiotics are viewed as protected to-eat.
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eretzyisrael · 2 years
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Development of synthetic embryo models from day 1 (top left) to day 8 (bottom right), when all their early organ progenitors had formed, including a beating heart, an emerging blood circulation, a brain, a neural tube, and an intestinal tract.COURTESY WEIZMANN INSTITUTE
Lit from below by the microscope’s soft glow, the translucent mouse embryos looked exactly as they should. On day 3 they began to elongate, from spheres into cylinders. On one end, the neural tube started to fold around day 6, on the other a tail began to bud. By day 8, a beating heart began to circulate blood through vessels forming around the embryo’s yolk sac.
But these embryos weren’t the product of an egg and a sperm. They weren’t even growing in the uterus of a female mouse. They were developed inside a bioreactor, and made up entirely of stem cells cultured in a Petri dish.
The experiments, performed at the Weizmann Institute of Science in Israel and published Monday in Cell, mark the first time researchers have grown fully synthetic mouse embryos — that is without the use of sperm or eggs — outside the womb.
The advance opens up new avenues for studying how stem cells form various organs in the developing embryo and better understanding how certain mutations drive various developmental diseases. It also raises profound questions about whether other animals, including humans, might one day be cultured from stem cells in a lab.
“As soon as the science starts to move into a place where it’s feasible to go from a stem cell population in a Petri dish all the way through to organ development — which suggests one day it will be possible to go all the way to creating a living organism — it’s a pretty wild and remarkable time,” said Paul Tesar, a developmental biologist at Case Western Reserve University School of Medicine who was not involved in the study.
Since the 1980s, developmental biologists have been taking apart embryos cell by cell to try to understand how they eventually become all the specialized tissues that allow fish to swim and mice to scurry and humans to walk and talk. In the last decade or so, researchers have learned enough about the signals that send stem cells down these differentiation paths to be able to put them back together into things that resemble organs (organoids), recently fertilized eggs (blastoids), and even embryos (embryoids).
But these balls of mouse and human cells could only be grown in dishes and test tubes for a short amount of time before they’d poop out. They needed a living womb to support their further development, or even better, an artificial approximation of one.
Jacob Hanna, an embryonic stem cell biologist at the Weizmann, spent seven years engineering a tubed system of spinning glass vials housed in an incubator to do just that. Last year, his team reported in Nature that their mechanical uterus could keep natural mouse embryos alive for up to 11 days.
“That really showed that mammalian embryos can grow outside the uterus — it’s not really patterning or sending signals to the embryo so much as providing nutritional support,” Hanna told STAT in an interview. The next step was to see what would happen if they put stem cells — rather than natural embryos — into their contraption. “Can these cells make an entire embryo? That was a big unanswered question for the field.”
In this latest work, the team combined that system with a novel cocktail of stem cells, some of which had been chemically coaxed to over-express genes that switched on development of the placenta and yolk sac — tissues that are vital for supporting the healthy growth of embryos.
The synthetic embryos were able to grow to day 8.5, developing the beginnings of a well-shaped brain, a neural tube, and an intestinal tract, as well as a beating heart. Analyses of the synthetic embryos’ gene expression patterns across different tissues showed that they were 95% similar to a natural mouse embryo of the same age.
“We found that these cells do have this incredible self-organizing capability that can be unleashed if given the right artificial settings,” said Hanna.
However, the work has some important limitations. Day 8.5 is still relatively early; the full gestational time for a mouse is 20 days. And the embryos that survived that long were a rarity. Only about 50 of 10,000 cellular clumps self-organized into embryos. The rest failed to develop properly.
“This is just one step, but a very important step for us to be able to study early development,” said Tesar. “We’re crossing into the realm of being able to generate an embryo from scratch, and potentially a living organism. It’s been a really notable switch for the field.”
While scientists have gotten very good at rewinding mature cells to the more primitive stem cell state, figuring out exactly which chemical signals will cause a stem cell to produce the precursors of a liver or kidney has been much more challenging. Experiments trying to nudge stem cells to form specialized tissues have tended to produce jumbled mixes of cells instead, lacking organization and with the wrong compositions of cell types.
Researchers say the new work from Hanna’s team should provide a way forward for getting those recipes right, in part because the transparent bioreactor allows scientists to observe organs developing in front of their eyes, but still in the context of surrounding support tissues. And because by starting with stem cells instead of fertilized eggs, they can produce these embryonic structures in a much more scalable and controlled way.
“This is going to tremendously refine the roadmap to tissue and organ formation,” said Nicolas Rivron, a stem cell biologist at the Institute of Molecular Biotechnology of the Academy of Sciences in Vienna. “It’s going to teach us the minimal structures, the minimal elements that will be necessary to eventually form full-fledged organs. That alone is absolutely priceless.”
Beyond basic research though, the bigger impact of this work is its potential to one day be applied to other species, including humans. Synthetic embryos derived from stem cells offer scientists the opportunity to probe in unprecedented detail the early days of human development while providing a less controversial and ethically fraught alternative to human embryos — the study of which has historically been limited by funding bans and the willingness of IVF donors.
The synthetic embryology revolution isn’t going to happen tomorrow. There are numerous technical hurdles to translation — humans have much longer gestation periods and they grow much larger than a mouse, as well as being a more complicated organism. But that kind of work always starts somewhere, and it usually starts with mice. That means it’s not too soon to start thinking about where this could all be headed.
“The more and more we show the capacity for pushing stem cell-derived embryos further and further in development, the more synthetic embryos and natural embryos begin to merge,” said Tesar. “There will always be a gray area, but as scientists and as a society we need to come together to decide where the line is and define what is ethically acceptable.”
Hanna, for his part, isn’t interested in synthetic embryos for reproductive purposes. The ultimate goal he’s working toward is making organs and tissues for transplantation and to treat human diseases. He sees synthetic organoids not as potential lifeforms so much as as biology’s best 3D printer.
“You can view this as a universal differentiation protocol,” he said. Rather than needing different complicated chemical recipes to make a stem cell become a liver or a lung, embryoids, even very early-stage ones can give a stem cell all the signals it needs to produce potentially life-saving therapies.
Imagine a patient with untreatable leukemia — they need a bone marrow transplant to survive. In Hanna’s future, scientists can take a biopsy of skin cells from that patient, wind them back into stem cells, grow them in naive conditions, and put them in this specialized bioreactor. The end result? An army of bone marrow stem cells that can be given to that patient, without them having to wait for a donor match that might never come. “It’s early days but we’re really opening up the field to explore these possibilities more seriously,” said Hanna. “We’re moving from science fiction to science.”
Last year, Hanna co-founded a company called Renewal Bio, also based in Israel, focused on testing how his lab’s technology might be translated into improving human health.
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dynamicdetoxqueen · 1 year
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