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gauricmi · 25 days

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Global Leigh Syndrome Treatment market is Estimated to Witness High Growth Owing to Increasing Disease Awareness

The global Leigh syndrome treatment market is expected to exhibit significant growth due to rising prevalence of the rare genetic disorder. Leigh syndrome is a rare and aggressive neurological disorder caused by mutations in mitochondrial DNA or nuclear genes involved in mitochondrial biogenesis and respiration. The characteristic symptoms of Leigh syndrome include developmental delay, loss of motor skills, weakness, vision problems, and respiratory issues. Currently, there is no definitive treatment for Leigh syndrome. Treatments mainly focus on managing symptoms by targeting the underlying cause. Therapies primarily include vitamin and nutritional supplements, physical and occupational therapy, and medications targeting respiratory and neurological complications.

The global Leigh syndrome treatment market is estimated to be valued at US$ 272.9 million in 2024 and is expected to exhibit a CAGR of 6.7% over the forecast period from 2024 to 2031. Key Takeaways Key players operating in the Global Leigh Syndrome Treatment Market Growth are Abliva AB, PTC Therapeutics, VAKS Pharma, MITOCH, Medley Pharmaceuticals Ltd., Khondrion BV, OMEICOS THERAPEUTICS GMBH. , Edison Pharmaceuticals, Inc. , Dainippon Sumitomo Pharma Co. Ltd., Taysha GTx, PicnicHealth (AllStripes), Takeda Pharmaceutical Company , Biogen, Ionis Pharmaceuticals, Inc., Sarepta Therapeutics, Inc., and MECOSON LABS PRIVATE LIMITED. The global Leigh syndrome treatment market is expected to witness lucrative growth opportunities due to increasing research funding for rare disease drug development and growing orphan drug designations. Furthermore, advancements in understanding the genetics and underlying mechanisms of Leigh syndrome are likely to aid the development of novel targeted treatment options. Key players are actively focusing on expanding their geographical presence through collaborations and partnerships with regional healthcare providers to cater to the growing patient population worldwide. For instance, in 2021, Khondrion partnered with Taysha Gene Therapies to accelerate the clinical development of KH-176, a gene therapy drug candidate for Leigh syndrome. Market Drivers The primary driver propelling the global Leigh syndrome treatment market growth is increasing disease awareness driven by advocacy programs by patient support groups such as United Leukodystrophy Foundation and Cure Sanfilippo Foundation. Growing government efforts to provide orphan drug incentives and streamline the approval process for rare disease drug candidates are also expected to encourage pharmaceutical companies to invest in Leigh syndrome drug R&D.

Get More Insights On This Topic: Leigh Syndrome Treatment Market

#Leigh Syndrome Treatment Market #Mitochondrial Disease #Neurological Disorders #Rare Diseases #Genetic Disorders #Pediatric Neurology #Metabolic Disorders #Pharmaceutical Industry #Drug Development

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femboyishcharm · 4 months

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being crippled makes u funnier

#i was looking at some shoes and thought these look more expensive than my leg braces #WHY OUT OF ALL THINGS-#also my favorite joke is i'm not like other girls.........i have a rare neurological disorder #bitching and Moaning

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rangpurcity · 1 year

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Celine Dion, who is going to debut in Priyanka Chopra's film, is suffering from neurological disorder, shows canceled

Celine Dion, who is going to debut in Priyanka Chopra’s film, is suffering from neurological disorder, shows canceled

New Delhi – Hollywood’s famous singer Celine Dion Soon she is going to step into the acting world. Celine Dion is about to make her acting debut with Priyanka Chopra’s film ‘Love Again’. But before his acting debut, a very sad news has come to the fore for his fans. Celine Dion has recently shared information about suffering from ‘Stiff-Person Syndrome’ neurological disorder by sharing a video on…

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tctrojan · 2 years

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What is FND FND stands for Functional Neurological Disorder. This is a rare neurological disorder which affects 4 – 12 people out of 100,000. This can affect every sufferer differently. The brain/nervous system fails to send and receive the signals around the body, which often leads to movement and sensory issues. In many cases, this is extremely disabling and unpredictable conditions. Often…

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#disability #disorder #FND #health #Neurological #rare condition #true

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room42 · 2 years

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Richard Engel Says Son's Rare Neurological Disorder Has "Progressed."

Richard Engel Says Son’s Rare Neurological Disorder Has “Progressed.”

Back in 2018, Richard and his wife, Mary Forrest, opened up about their son’s condition during an appearance on Today. At the time, the couple recalled how they came to learn of Henry’s diagnosis. Richard explained that after taking him to multiple doctors, they made the choice to do a full genetic scan. “I called the doctor and he said, ‘We found something and It’s very, very severe and it’s…

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#Disorder #Engel #Neurological #Progressed #Rare #Richard #Sons

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incognitopolls · 4 months

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We ask your questions so you don’t have to! Submit your questions to have them posted anonymously as polls.

#polls #incognito polls #anonymous #tumblr polls #tumblr users #questions #polls about brains #neurotypical #neurodivergent #neurodiversity #brains #mental health

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am-i-the-asshole-official · 3 months

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WIBTA for putting my fic on hiatus right after a cliff hanger chapter? 📝✍️🗝️

So this is pretty low stakes and petty, but I genuinely feel like I'd be an asshole here and I wanted a second opinion.

I've been working on this fic and its sequel for a couple years now (neurological disorder so writing is really difficult and slow for me), but more and more it's just starting to feel like it's just not worth the effort to post. I know people are reading bc I can see the hits number going up, but it's really rare that I get kudos and I only have like one reader that consistently posts a comment. It's gotten to the point where I just uploaded a chapter last night and didn't even feel excited about it, just cried bc I was already anticipating getting no engagement on it.

Reasons why I think I might be the asshole for the hiatus:

-I know it's really shitty to just drop a fic like that, even if you're planning on coming back to it eventually. Especially when it's on a major cliff hanger

-It feels rude to expect more engagement than what I'm currently getting since I'm not popular in the fandom.

-I don't want to punish the readers who do leave comments just bc I can't handle the fact that most readers don't leave comments.

So WIBTA for this?

What are these acronyms?

#aita #am i the asshole

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muttren · 6 months

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i have a disability. more specifically, i have a rare genetic condition called camurati-engelmann’s disease, or CED. it is also known as progressive diaphyseal dysplasia (PDD). it is an extremely rare disorder and only around 300 cases have been reported worldwide.

i figured i would make a post talking about it, in an effort to not only educate others, but to possibly connect with others who suffer from it as well. i apologize for the longer post but please this moment to learn about my disorder.

CED is a skeletal condition that is characterized by abnormally thick bones (hyperostosis) in the arms, legs and skull. the overgrowth in bone causes bone pain, muscle weakness and extreme fatigue. the pain feels like an electric stabbing pain, an ever-increasing pressure sensation around the bones affected, or a constant aching. pain can also occur in joints and they will often lock-up, becoming immobile and stiff. the pain is especially severe during 'flare-ups', which can be unpredictable, exhausting and last anywhere from a few hours to several weeks. this is a common occurrence for us, often causing extensive sleep deprivation from the chronic, severe and disabling pain. when this happens, we are often bedridden or housebound for days or even weeks.

those affected also have an unsteady walk and limp. thickening of the skull can also lead to neurological problems, like hearing loss, vision issues, vertigo and tinnitus. symptoms vary in severity from person to person. there are treatments, however it cannot be cured. pain management is a large aspect of living with this chronic disease.

there is very little awareness and research for CED. rare diseases are severely neglected and overlooked, as are those who suffer and live with them. research is often not considered profitable due to their cost to develop and the limited patient population. major federal funding agencies give preference to research that is likely to have a direct impact on patients.

living with a rare disease is extremely difficult and isolating. it impacts the lives of millions of us and our loved ones worldwide. those of us suffering from rare medical conditions should be entitled to the same quality of treatment as other patients. i am disabled, but i am worth it.

#camurati engelmann’s disease #ced #progressive diaphyseal dysplasia #pdd #disability #chronic illness #chronic pain #disabled #chronic fatigue #chronically ill #rare disorder #rare disease

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aeithalian · 1 year

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Rick. Buddy. Amigo. Explain something to me. Real quick, I promise.

[The Trials of Apollo: The Tower of Nero, Chapter 4]

Good genetic package, Rick/Apollo? Are you sure about that?

Listen.

Estelle's physical description *clap* makes *clap* no *clap* sense. Why on earth does one of the only fully human characters in this series have to have unique and weird physical traits? Also, it makes no sense in the larger scope of Rick's writing style to have chosen this unless he had some sort of larger intention behind it. Not to mention the theories by fans haven't really done much to fully flesh out any perceivable reason as to why this might be:

Poseidon blessed Sally when she was pregnant - By far, this is the most believable to me, but it's still eh, because this feels very weird and I don't get the vibes from Poseidon that he would have done so to the extent that it shows up in Estelle's physical traits. Also if that were true, it doesn't make sense for Rick to just fully drop it in the story without the intention to flesh it out further, because to my knowledge he doesn't have plans for another novel that takes place after ToA.

Paul isn't Estelle's father - Firstly, this is out of character for Sally, and this doesn't fully justify why Estelle has Percy's eyes. PLUS, salt-and-pepper hair still wouldn't be natural for a newborn

Paul is Poseidon in disguise - This explains her traits the best, but Paul's character is so much more satisfying if this isn't true. It's also total bullshit.

Enter me. I have a theory. Yay. But first, we must discuss.

Firstly, I want to talk about her eyes. Going back to the theories, and based on my fair amount of knowledge of genetics (clarification: I write this as I procrastinate studying for my final genetics exam), the eyes are mostly interesting because Apollo specifies that they are immediately similar Percy's. The thing about eye genetics, though, is that they are what we consider to be 'complex traits', meaning that they are influenced by the interactions of multiple genes from both parents. What I mean to point out here is that Sally could definitely have the genes to produce two children with 'sea-green' eyes, considering her canonical eye color is blue. We don't know what Paul's eye color is, which makes my job a whole lot easier because I can assume that it doesn't directly contradict the possibility that Sally just has really strong eye genes (?). ALSO, who's to say that Poseidon didn't just change his eye color to match Percy's when he was born? Ah, yes, the perks of having a shapeshifting dad who seemingly loves you and your eye color a lot (but is still absentee, WHOOPS).

But what I actually found the most interesting about Estelle was her hair color. More specifically, the fact that Apollo says he's never seen an infant with that color hair. And we know Apollo is somewhat of an unreliable narrator (although this rarely affects his descriptions of people other than himself, and has also mostly evolved into a more honest narration since the end of book 3), but I believe we're supposed to trust this dude who just so happens to have been alive for over four millennia. Based on Apollo's previous descriptions of his own powers (see his conversations with Percy in TTC, when he pulls a Mufasa and basically admits to seeing everything the light touches), we know that Apollo knows and has seen a lot of stuff. So, how is this the first time he's seemingly witnessed this type of hair mutation?

I did some research, as one does. To me, it seems as if Estelle has what's called Griscelli syndrome, which is a type of rare autosomal genetic mutation that typically results in phenotypic hypopigmentation of the skin and hair. (It can also result in neurological disorders and immunodeficiency, based on the type, but I digress.) It's also pretty rare, considering both parents have to be carriers, and even then the child still has a one in four chance of being affected. Current statistics from the NIH say that Griscelli syndrome currently presents in less than 1000 Americans, and is rapidly fatal in 1-4 years without aggressive treatment.

That sad note aside, it's weird to me that the way Rick wrote Estelle's physical description makes it seem as if Apollo had never seen anything similar. I feel like a god of both medicine and knowledge would probably be a bit more up to speed with rare genetic disorders, especially because he's so old. The only explanations are that Apollo, in his mortal state, can't make a diagnosis, OR what he's seeing isn't actually something he can diagnose.

FURTHERMORE, from the same chapter, Apollo says something that muddies the waters even further:

It doesn't make sense that Apollo thinks that Zeus would take such an interest in Estelle. Her nature alone doesn't make me think that the king of the gods would take a sudden interest in a literal newborn, regardless of how much Apollo loves her (and honestly, I don't blame him).

What I think? Rick pulled the strings just tight enough that he has a very interesting plot point to go off of if he ever decides to pick up the pen again and write a new book.

What I think? Estelle doesn't have Griscelli syndrome, she is in much more danger than anyone realizes, and Apollo's subconscious put this together from the second he saw her.

Actually, let's rewind. I'm in the process of writing a fic (stay tuned!) and I had a random thought: do the Greeks have an apocalypse story? You know, like Ragnarök in the Norse mythos, and the Revelation stories in the Bible.

The answer? They don't. I guess that's what you get when the Greco-Roman gods are fully immortal and literally can't be killed.

That didn't stop the rabbit hole, though, and what I found was actually very interesting and I couldn't believe what I was reading.

I give you: Hesiod. More specifically, his poem Works and Days. More more specifically, his 'ages of man'. More more more specifically, the iron age.

For context, Hesiod was an ancient Greek poet who lived in the 8th century BC, and was walking right along with Homer in terms of fame at the time. The poem Works and Days is actually more of a really long Facebook post where he complains about anything and everything, especially in his section on the ages of man.

In summary, Hesiod wrote about what he perceived to be the five stages of human life since the creation of mankind by Zeus' hand:

gold: perfect in every way, pious, and blessed by the gods

silver: real bitches, the ugly middle child, so Zeus killed them

bronze: were so violent they wiped each other out

heroic: golden child, contained the heroes of the Greek mythos

iron: middle-aged men still living in their mom's basement

Hesiod wrote his poem during what he perceived to be the Iron age (it's really just him complaining about being born in the wrong generation), but he ends up listing a lot of qualities: 'everyone works too hard, the gods hate us, nobody respects family values anymore', blah blah blah.

I know what you're thinking: Tia, what does this have to do with an apocalypse?

Well, dear reader, bear with me. You see, every time Zeus didn't like an age of mankind, or it became too violent, or it generally wasn't pious enough, Zeus wouldn't hesitate to destroy that race and start over. Basically, an apocalypse.

So, you may ask a new question: what is the criteria for Zeus to destroy the Iron age? And, assuming that this is the age we're currently in, what would it take for Zeus to destroy everything our beloved Riordanverse characters know and love?

My friend, that is where Estelle comes in. Yes, a baby.

Take this excerpt regarding the Iron age:

"And Zeus will destroy this race of mortal men also when they come to have grey hair on the temples at their birth."

I think you see where I'm going with this.

My theory? Estelle, in her unique position as a bridge between not just the mortals and the demigods (eg. her relationship with Percy), but also the mortals and the gods (eg. her great impression on Apollo), is a living, breathing prophecy. A prophecy that the end is nigh for this current age of mankind.

Furthermore, I also think that Apollo made this connection, somewhere in the back of his mind, the very second he realized that her hair was entirely unique. According to Hesiod (who Apollo also mentions later in the book, so we know he knows who Hesiod is), the day that babies are born with gray hair (or, salt-and-pepper for the sake of the theory) is the second Zeus basically get the go-ahead to commit genocide.

This also brilliantly explains why Apollo suddenly, and seemingly without reason, makes to keep Estelle's existence a secret from Zeus, because he knows that it might be the easiest way to get everyone he knows and loves killed by his own father for "the greater good" as I'm sure Zeus will put it. Plus, in his mortal state, Rick didn't have to explain why Apollo did what he did, since Apollo's been having memory issues since the beginning of the series: why would he remember one line from a poem written almost three thousand years ago?

Frankly, Zeus doesn't care about mortals: the only reason he really cares about anyone is if they have enough power to threaten his own, or if they have some sort of power he can benefit from. This, certainly, falls under the category of the latter. Wouldn't you want a chance to remake humanity into the perfect image that it used to be? You would, if you hadn't gone through a five book long grow-a-conscience speedrun like our lovely Apollo over here.

Fortunately for Rick, this is such an outrageous theory that if it never comes to fruition, I won't be surprised. If he ever writes something similar, though, know I called it first.

EDIT: here's the fic i mentioned i was (am) writing

EDIT: a masterlist of my other metas

#riordanverse #trials of apollo #apollogists #also that fic i mentioned will definitely be including this #estelle blofis #theory #fan theory #also if you were wondering my genetics exam went well thanks for asking

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scientia-rex · 5 months

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What caused you to choose family practice after med school? What different specialties did you consider?

I kind of always knew--I started out before I knew anything thinking I wanted to specialize, maybe neurology given my history with Neuroscience, but once I shadowed a couple of doctors I was like "Oh. Family Medicine. That's what I like."

It's got a little bit of everything, it's impossible to be truly good at--I'm constantly forced to learn new things about every specialty because out here we have no one. I need to be half a nephrologist, half a rheumatologist, half a dermatologist. I do a crap ton of procedures--I like them, I like the satisfaction of an IUD insertion or a cyst removal done well. I will stay busy forever. I will never have a chance to get bored. I can do migraine care, manage Parkinson's, diagnose dementia, remove some skin cancers, differentiate between polymyalgia rheumatica and statin rhabdo--if I wanted to, I could still be doing hospital care, I could still be delivering babies. I have so many patients who either don't want to or can't drive two hours to the closest city for specialty care, and if I don't learn this, fast, and well, they'll get nothing. So there's always a fire under my ass. Rare genetic blood disorder? Shit! Read up! Molar pregnancy? I've seen two. Rural medicine is fucking wild and it's my happy place.

I recommended reading Med School Confidential for a better handle on a lot of this.

#the attending dr. kristophine

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nyaagolor · 11 months

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What's going on with Nemona's wrist?

this is mostly just me putting down all my thoughts about this hc I have. Below the cut bc it's long as usual but read on if ur interested in like. orthopedics

I think Nemona has fatigue and some kind of wrist Issue because 1. She implies she has decreased motor function in that arm (can't throw pokeballs well, supports her arm with her other hand during battles) 2. She wears a brace 3. She gets winded easily / needs to catch her breath more than other characters / hates stairs So that got me wondering what the cause could be. I work in an orthopedic office and my shifts are 12 hours so sometimes when it's slow and I'm bored this is what my mind wanders to

Option 1: It's carpal tunnel and she's out of shape This is the most obvious answer since carpal tunnel is a repetitive stress injury and she's wearing a brace that looks almost identical to irl braces for that problem. Throwing pokeballs over and over, especially incorrectly, would be the most likely cause of an asymmetrical injury like that, and is actually reasonable for someone of her age and activity level. The winded thing is just because she's out of shape and has no underlying cause. Or maybe she just has some kinda chronic pain / fatigue disorder. That's not my department idk

Option 2: Oligoarticular JIA (juvenile idiopathic arthritis) This very long name is just describing chronic joint swelling in children that affects less than 5 joints. It's an autoimmune disease, and actually not that uncommon all things considered. It causes stiffness and pain, which would explain the stamina issues and motor skill issues. Plus, the constant flexion and extension of the knees from staircases certainly would explain her distaste for them in particular. That shit hurts. Occasionally people will use a brace for JIA-- it's highly unlikely her wrist would be the worst considering the typical presentation patterns (it usually affects bigger joints first like the knees) but hey. It's possible! This condition also affects young girls more often than other groups so. Math checks out

Option 3: Ehlers-Danlos Syndrome (hypermobility type) Figured I would include this bc I've seen a few people hc this and wanted to give it a fair shot myself. This is a heritable connective tissue disorder that causes hypermobile joints, chronic pain, fatigue, and a whole host of other things. Specifically tho, this disorder used to be called EDS type III and is now considered part of the Hypermobility Spectrum Disorders, but that's a can of worms for a post that's not this one. While the symptoms do match, and honestly quite well (a brace for stabilization makes perfect sense and the fatigue symptoms feel pretty on the nose) the disease usually causes very stretchy skin and vascular issues that she doesn't seem to have so I'm a tad on the fence

Option 4: Cervical spinal stenosis Despite this being the first thing that came to mind for me (since I see it a lot in the office) I'm now less convinced this would be the case. This disorder is basically a narrowing of the spinal canal that pinches the nerves in the neck. It can cause pain, weakness, numbing, and pain that radiates down the body. If most of the compression was on the C4 and C5 nerve I can see it affecting one arm / wrist especially rough (since the pain is typically bilateral but asymmetrical) but also this occurring in people under the age of 50 is SUPER rare so eh. It's possible it was congenital or caused by an injury but I wouldn't bet on it. As for the stamina issues, the neurological issues caused by the compression would likely be the cause of that, especially radiating down the back and legs. Felt worth it to include even if I'm not 100% convinced

I'm saying "options" here bc these symptoms are super vague and there's like 80 billion things that could cause it, I'm just racking my brain for different possibilities. If anyone has other hcs for the underlying causes of Her Whole Deal lmk I'm curious

#i know this is completely deranged but it's pride month let me have this #nemona #pokemon sv #headcanons #mod vex

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sygneth · 1 year

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I am not even sure if I will be posting this (though, if you're reading this, I did), but, nevertheless, I have a few points about Jean that I have to make. He is no saint. He is an asshole and I’m not gonna pretend that he is not. But there is so much more to it.

Let me start with the most obvious. He is said to have clinically diagnosed depression, with, apparently, no distinctive source, and, from what he says, we may assume he is under some sort of psychiatric supervision.

He was diagnosed seven years ago. Diagnosed with depression, which probably means he’s been dealing with it for a good while longer, only at a certain moment he decided to seek help/had an attempt/any other circumstance that lead this man to get a diagnosis. He is now 34, seven years earlier he’d be 27.

The reasons for such unspecified depression may be many, from some kind of a rare neurological defect causing one’s brain to be incapable of properly producing/transmitting/I’m-not-a-biologist-neither-is-English-my-first-language-so-I’m-not-gonna-dig-into-neurological-dysfunctions-further-but-you-get-the-point, serotonin, through a burnout, all the way to having other, undiagnosed disorders/illnesses as *checks Luiga’s tweets* Schizoid PD (I am not convinced that what Jean presents is a 100% textbook SPD example, rather SPD traits/behavior patterns? But I’m no specialist and even if I were, it’s hard to diagnose someone based on those few dialogue lines) and codependency tendencies. The doctors didn’t diagnose any other disorder, or at least he never mentions it, but looking at the world of Elysium, those disorders may not yet have been widely recognized, especially if not presenting themselves in the most typical ways/high-functioning. And Jean tends to be high functioning despite his issues. Yet, I assume that in Elysium, and Jamrock especially, the access and quality of psychological and psychiatric services are poor and probably limited. Not to mention education on the matter, which is probably low if not near none. (Just looking at how is alcoholism treated by *everyone* there, or the short mention of McCoy’s brother gives me a good 90’s/early 00s Eastern Europe vibe of mental issues/disabilities public awareness.) Now, keep that in mind.

Alright. Next up: a codependent, close relationship with an alcoholic.

Jean’s relationship with Harry is an interesting one. I found this interesting research on codependency among spouses of alcoholics, that states codependency is related to, among others, SPD traits. (That’s an, uh, disclaimer? I was just curious how that two may coexist, but apparently, they do.)

Back to the main thought.

As someone who has been in a close, codependent relationship with a person who had problems with drinking, I can tell you something. It’s more than hard to get out of one. You see a person you care about do stupid, drunken, dangerous shit, you may be angry at them, you may be furious, yet you will still feel responsible for them in a way, and you will take that responsibility and try to get them out of the shit they got themselves into. I’ll say more, if that’s an actual relationship, you will feel social pressure that you are responsible for your partner’s behavior and you’re the one to take care of them. If it’s your work partner, then it’s highly probable you actually will be held responsible for their behavior, so you’re even more likely to clean up their mess. And when you help them out, because you care, because you feel like you should, because you don’t want to be “dicked” for it, maybe all of the above, they will be grateful and they will praise you and love you and even if you feel like this is not the right thing to do, you will do it again.

It takes a lot of work and self-awareness to get out of something like that healthily. And if you have some psychological knowledge, it also helps a lot, to understand how to deal with it. And the only way to do it, regardless healthy or not, is by setting boundaries. If you can healthily set them, and make the other person respect them, that’s very good. But if you have some other mental issues in addition to that, if you lack knowledge on how people’s behavior patterns work, on how exactly addictions work and that, you are maybe having some problems with generally understanding relationships between people, how and why they work, it’s very likely that you won’t be capable of setting those boundaries and enforce them to be respected. It’s very likely that one day, when something will happen and you will realize how toxic and unhealthy this relationship is for you, you will panic and you will start to do anything to get out of it, like a cat drowning in a well. That you will start acting cold, maybe even merciless from a certain perspective, maybe you won’t let yourself believe in their pleading and assurances of change, because you will know that letting yourself *feel* sympathy for the person you had this relationship with may lead to spiraling back into the wheel of codependency. Maybe you have already tried this, and letting yourself trust them only led you back to the point where you started and maybe this time, you don’t want it to end up this way.

And you know what? There is nothing wrong with trying to ensure your mental well-being. “Before approaching the casualty, always make sure the area is safe.” YES because if you’ll get hurt trying to help somebody, there will be one more person to help. The same applies to helping people get their life together. If you won’t have a good mindset to help them, if they will only drag you down, maybe the area isn’t safe?

Moving on.

Now, remember when I said that the level of social and psychological awareness seems very low in Elysium/Revachol/Jamrock? About that.

You know what else I see, looking at the Harry-Jean-Dora-Kim situation? A bunch of people with self-awareness in terms of emotion, and emotional development of teenagers, but problems of grown-up people. And they are not to blame, the system is to blame. Harry seems to be very self-conscious and connected to his emotions, yet for six years he couldn’t find a healthy way to get over a heartbreak. He has tendencies to act violently, to randomly drunk-phone his ex to harass her (I mean come on, he was asking her if she is naked), not to mention a tone of other things.

What happens here to Jean, is his situationship/best friend, whom yeah, he decided to ‘have a break’ with, immediately gets over it, and starts to go out with someone else. Taking, that this man has probably understanding of his emotions on a level of a high-schooler, he WILL be salty. He will be mad at Harry and he will be salty towards Kim when he sees them in Whirling. (Not to mention that it’s probably how they just roll in the precinct, and I’m quite sure that Harry’s and Jean’s relationship has been japing on and teasing each other, and as long as they both knew how it works, it was all good, compare: this post. So yes, Jean will be angry with Harry and he will act like an offended drama queen partially because that is just how their relationship dynamics probably looked like for the last two (at least!) years, and partially because he is an offended 16-year-old drama queen, whose bestie told her to fuck off and found a new (boy)friend.

Is it good, that grown-up men have the emotional capabilities of high schoolers? No. Should we blame them, or the fact that their system seemingly doesn’t provide any prevention, doesn’t promote awareness, or offer any proper healthcare for that matter? I’ll leave that to you.

To add to all this, yes, the RCM’s fucked up system, hierarchy, and mentality don’t help. Yes, it would be better for both Harry and Jean and probably Kim too, taking for his PTSD, to get the fuck out of there and live peaceful lives. But you know, changing your whole lifestyle isn’t easy. Understanding that maybe it’s better to leave now and that it doesn’t mean you’ve “wasted” your years is a process, a long and hard one. I had to learn this. My close ones had to learn this. Some of them still didn’t, especially, that where I come from, there is this CEE culture of not letting yourself fail with peace of mind. You got to do everything the best you can, you gotta do it 120%, and if not, you’re a rotten piece of shit. Looking at how Harry treats himself, Revachol seems to have this in common with Central-Eastern Europe as well.

Another thing, we don’t even know what Kim or Jean did before they joined the RCM, and Harry was a gym teacher. Thinking that it is easy to just switch your job in, again, a place with a CEE mentality, is a huge mistake. At the age of 40-odd years especially. In the 90s, especially. We don’t even know if Jean or Kim have any other education on their account, besides being cops, so changing professions would mean additional education, and for Harry, how many places, realistically, would take in a 45-year-old gym teacher?

I generally see that many people seem to forget/not understand how CE European mentality works, and it shows. I am glad that we live in a world where awareness of things such as homophobia, ableism, misogyny and else is common knowledge. But it wasn’t here, not even those 15 years ago. I remember people using names of dysfunctions and disabilities as slurs. Grown up people. I remember my classmates and my friend calling each other faggots or laughing at each other for not being gender-affirmative enough. Half of us turned out to be queer, and nobody had a problem with that, because in those times this kind of language wasn’t necessarily indicating someone’s worldview, it was just a bad habit, a very common one. I am more than happy, really, that we got rid of this kind of narrative and are more aware of the weight of a spoken word now. But when talking about past or settings that resemble this past, let’s please not forget that it DID look different and take that into consideration. Please.

Remembering what we derived from and what a great progress as a society we did is important, as it shows the way we managed to walk, but also reminds us of what people had to deal with. And is a warning, because now we’re probably still all doing things that in 30 years will be so, so wrong.

So concluding this ridiculously long consciousness stream, I love you, DE fandom. Now, I have an interview to watch (probably not anymore) and a comic page to draw (as always). I’ll leave you with this here.

#deep dive into #jeanalysis #jeanposting #jean vicquemare #deep analysis #jean heron vicquemare #disco elysium #disco talking #disco elysium meta #if i only had this much passion to write my master thesis

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