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#hsv infection
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#1 HERPES & STD DATING COMMUNITY & SUPPORT RESOURCE FOR POSITIVE SINGLES
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herpesdatingsingles · 2 years
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 "There is always madness in love. But there is also always some reason in madness.
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debashreeduttadd · 2 years
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HSV Eraser Best Review #debashreedutta #shorts
HSV Eraser is a 21-day program kit that helps in the treatment of herpes. The creators, Dr. Christine Buehler and Dr. Ken Languin, claim that no conventional medicine can treat herpes HSV, or herpes, is one of the most popular diseases among people of all ages.
To know more click here
#HSVEraser
#Eraser
#HSV
#debashreedutta
@debashreedutta
#shorts
#short
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livingwithhsv · 1 year
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instagram
😂😂😂
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med-school-studies · 2 years
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Neonatal HSV
**50% chance of transmission during vaginal childbirth
**60-80% of mothers who deliver have no evidence of outbreak (internal sores not visible)
**C-section common preventative measure
**SEM present 10-12 days of age: skin eye and mucous membranes only
**grouped vesicles usually in eye
**Disseminated HSV (DHSV) within 24 hours (whole body, bloodstream and spreads to brain) DEADLY TO NEWBORNS
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pharmaproff · 2 years
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HPV and HSV Infections – Epidemiology Insights and Forecast 2016-2028 by Pharma Proff
HPV is a group of more than 200 related viruses, which spreads mostly through anal, oral, and vaginal sex. The sexually transmitted HPV infections are categorized into two groups: low-grade, and high-grade HPVs. HPV is generally transmitted through vaginal intercourse, oral and anal sex, and also by intimate skin-to-skin contact. The condoms and dental dams can reduce the likelihood of HPV transmission. Some of the risk factors of this infectious disease are smoking, infectious HPV type, increasing age, immunodeficiency, unprotected sexual intercourse, and presence of other sexually transmitted infections (STIs).
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HSV on the other hand is a viral infection which affects the mouth, genitals, or anal area. The virus can spread from one person to another causing outbreaks of sores. HSVs can be categorized into two types: HSV-1 and HSV-2. HSV-1 is majorly transmitted by oral-to-oral contact via sores, saliva, and surfaces in or around the mouth. However, HSV-1 can also be transmitted to the genital area through oral-genital contact, which leads to genital herpes. HSV-2 is mainly transmitted through contact with genital surfaces, skin, sores or fluids of someone infected with the virus.
Browse report overview with detailed TOC on HPV and HSV Infections – Epidemiology Insights and Forecast (2016-2028)
India is projected to have the highest number of incident cases of HPV and prevalent cases HSV infections, amongst the 12MM, followed by China and the U.S., during the period 2016-2028. Moreover, Germany is estimated to have the highest number of incidence cases of HPV infections and prevalent cases of HSV infections, while Spain is anticipated to have the lowest number of cases, amongst the European Union five (EU5) countries (U.K., France, Germany, Italy, and Spain).
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lazyjellyfish300 · 4 months
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Still and All🌿
Miguel O'Hara x Fem reader
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Gif credits to @miguelo-hara
Synopsis: You have a lifelong sexually transmitted infection. You've learned to live with it, but you started dating Miguel, and you need to tell him at some point. Word count: 4.7k
TW: MINORS DO NOT INTERACT. STIS: HERPES SIMPLEX VIRUS 2, TALK OF UNPROTECTED SEX, RELIGIOUS TRAUMA IMPLIED, INSECURITY, SLUT SHAMING, SELF DEPRECATING THOUGHTS, ANGST, STIGMATIZED THINKING ABOUT STIS, TALK OF SAFE SEX INCLUDING CONDOM USE, SMUT AT THE END( EVENTUAL UNPROTECTED P IN V, SPANKING, ORAL F RECEIVING), IN SHORT THE SUBJECT MATTER IS RATHER HEAVY AND IF ANY OF THE ABOVE IS SENSITIVE FOR YOU, TAKE CARE OF YOURSELF AND SKIP THIS ONE. ❤️
A/N: I DREW ON PERSONAL EXPERIENCE TO WRITE THIS. I HOPE WE CAN EVENTUALLY COMMUNICATE OPENLY ABOUT SEXUALLY TRANSMITTED INFECTIONS AND DISEASES WITH NO STIGMAS ATTACHED. BE SAFE AND HEALTHY. I GOT MY INFORMATION FROM THESE SOURCES, ALTHOUGH THE INFO IS IN LINE WITH THE SOURCES, PLEASE DO NOT USE THIS WRITING PIECE AS A SUBSTITUTE FOR MEDICAL ADVICE. TALK TO YOUR PHYSICIAN.
World Health Organization
Hopkins Medicine
Herpes.org NZ
-----
You weren't sure how you'd tell him. Or exactly when you'd tell him. You had told others before, but this time was different. You really really liked him. If you had the ability to envision someone you wanted to do the rest of your life with, he would be it.
And what you needed to tell him could cause you to lose him forever. And that news was that you had a sexually transmitted infection. Herpes Simplex Virus 2. Or HSV-2 for short. And you lived with it for years. It wasn't a big deal, really. But it took you a long time to get to this point.
You wondered if your strict religious upbringing and being repressed for most, if not all of your adolescence and young adulthood were contributing factors. It all came to a head when you were finally an adult and could move out of your parents' hypervigilant gaze. You started feeling excited at this new found freedom but went a little crazy with it. You started dating casually. It was exhilarating and felt empowering to be desired. To know that men wanted you, craved you, and desired to know the deepest, most intimate parts of your body.
So, you had some fun.
It was clear most of the guys you dated weren't as educated on safe sex either, or the passion of moment just threw those safety precautions out the window. It was careless, yes. And absolutely risky. But you didn't know how to ask for these things and weren't taught how to. You were afraid to speak up, that they wouldn't want you anymore if you put your foot down.
Several months into your promiscuity, you had a sinking feeling in your stomach you should go get tested when you felt an odd tingly sensation in your genital region. You prayed that nothing was wrong.
The doctor could not have called you at a worse time. Right in the middle of your shift. You stood in the stairwell of your job, waiting for a sigh of relief or your entire world to come shattering down.
"Your blood work looks good, except..."
There it is. Except.
"You tested positive for HSV-2. You have genital herpes. It is a very treatable condition, but there is no cure."
Just like that, a life sentence. You were super young when this happened, so to you this was earth shattering. Your mind didn't even pick up the rest of what he was telling you as you hung up your phone.
The world outside seemed to grow fuzzy as though someone bludgeoned you in the back of your head. Colors rapidly disappearing, causing your retinas to only see gray. Claws of despair sinking into you. Not able to speak, not able to think, gasping for air while the tide crashed and beat against you again and again, keeping you under, forcing you to drown.
Your mind did what it does best and became your worst enemy.
"Nobody's going to want someone like me."
"I'm dirty."
"If you weren't such a careless slut maybe this wouldn't have happened to you."
"Quit crying, this is just a consequence of your actions, deal with it."
"You're being punished. Maybe if you weren't so weak and didn't lose your faith, God wouldn't have had to teach you this lesson. You wouldn't need to learn it if you were actually good."
"Typical for a pathetic girl like you with daddy issues who can't go a month without a guy telling her she's pretty. See what happens when all you're good at is spreading your legs?"
Your internal monologue flogged you like this for months. You had to take some time to just cry, just lay in your bed and wait, praying to the God that abandoned you. The winds and rains of self-doubt and misery mercilessly beating against you while you hid in a hole, waiting for the storm to pass. A numb expression on your face as you watched everyone outside live their lives while you just stayed frozen in place with a dark cloud over your head.
Just holding on for better days that hopefully laid ahead, hoping you'd make peace with this permanent new part of you that seemed to latch itself onto you overnight.
And... slowly, you did.
You started taking antiviral medication. And it improved your symptoms drastically. Having an outbreak could be quite painful and uncomfortable. Gritting your teeth and your eyes squinting in pain when you had to use the restroom with open sores, the sting causing you to suck air between your teeth.
Once you got the hang of taking your medication on a daily basis, any outbreaks you experienced were only a couple of times a year, usually popping up only if you were under extreme stress or if you had missed a few doses.
Outside of your physical health, dating was tricky. You pretty much began to avoid it altogether, despite the raging loneliness within you. You just wanted to know what it was like to recieve the love you were so ready to give someone else. To have someone hold you at night and stand across from you at the altar as you pledged to spend your lives together, a conscious decision to not let this condition stand in the way of you two being together.
Most people were understanding, but eventually they'd stop talking to you. The unmistakable shift in your dynamic as soon as you told them when things started to get good. You respected their right to not put themselves at risk while you simultaneously grieved for just once, to hear someone say,
"It doesn't bother me that you have this. I still want to be with you. Let's figure this out together."
You came across someone who also had it. But the relationship never grew into something serious for other reasons.
You took a long break. Just to find yourself and be comfortable with being your own person. Not letting yourself settle for less than what you deserved.
Eventually you found Miguel, who was a welcome change to all of that. After college, you were Spider Society's fresh new accountant, sticking out like a sore thumb amongst your STEM and Spider-Colleagues.
Miguel noticed you while he was walking to the break room for another pot of coffee. This wasn't even the usual way he'd go, but after a casual glance in your direction at the way your eyes were narrowed at your computer screen, lips slightly parted in concentration, he switched his route to include an accidental brush past your open office door from then on, intrigued with this new face around the place.
You noticed him the second time he passed by, and you had to do a double take. He was gorgeous. Strong cheekbones that led into a chiseled jaw and wide neck. Warm umber skin surrounding scarlet seas of his eyes and full, pouting lips. A majestic, tall frame that embodied strength in every sense of the word. The evidence lay in the fit muscles that crowned his entire body from his arms, to his legs and whew, that stunning back.
The third time, you noticed him approaching and gave a little nod of your head with a closed lip smile, the generic, passively kind, but also slightly aloof way that acquaintances passing would give to each other. He returned the gesture, and you felt your stomach do a little flip as he walked away.
Next time, you actually flashed a smile, and he raised an eyebrow but gave that lukewarm expression of acknowledgement again. Not quite a smile yet.
Oh, but the first time he smiled at you. That sealed the deal. At first, you felt that maybe you were in danger of just being in lust with the guy, his physical features the first thing to pull you in. But when he flashed that dazzling smile at you, you knew immediately that your heart was in actual danger of being absolutely wrecked by this guy at some point. The bottom row of his teeth were ever so slightly crooked. His bushy, sculpted brows so expressive despite the stoic disposition that always painted his face. He was sooo...so...
Perfect.
His laugh and his voice was a whole other issue entirely. His voice wasn't exactly deep, but it was gentle. A sweet caress against your eardrums. It dripped like honey. That small, whispery chuckle of his he'd let out when you finally made small talk with him had you wanting to bash your head against the wall.
"Top o' the mowwwrning to ya! " you said in a silly voice as he walked up to your desk.
He cracked a smile. "What's got you in such a big mood this morning?"
You smiled like you were keeping a secret. "Oh, just the fact that it's Friday, it's payday, I have a 32 ounce iced coffee, and I have theeee best job in the world!" (A little bit sarcastic about the last item you listed)
Miguel scoffed. "Well, I'm glad someone is happy around here. I can't seem to get any peace and quiet or work done with all these shocking anomalies we've been dealing with lately."
"You wanna know a secret?" You ask, raising an eyebrow, feigning mystery.
Miguel rolls his eyes but is unable to suppress a smile. "Dime." (Tell me)
"The bench at the bottom of the hill in the courtyard is actually the best place to go to get some work done. But don't tell anyone else about it because that's where I go on my lunch breaks."
Miguel's eyebrows raise. "Is that so? Well, you don't mind if I were to try it out this afternoon?"
You grin and swish your iced coffee. "Nope! All yours. You gotta text me about it and let me know how it went, though. Tell me I'm right."
Miguel scoffed. "You're on. But, I don't have your number."
Your cheeks burn a little bit but you scribble your number down on a sticky note and hand it to him. He shoots one more stunning smile at you and walks away.
Later, he did text you that you were absolutely right. Peace and quiet for a whole two hours outside managed to get him to complete 3 weeks worth of paperwork he was behind on. You felt like you were on top of the world, but it escalated to a whole new level when you were straddling his lap in the backseat of his car after your first date just a week later, making out with him in a quiet parking lot at the head of the trail where you two went on a hike together.
You were getting lost in how tasty his lips were, soft and full with just a hint of his sweat from the exertion. You feel the heat of the moment about to overtake you when he starts to grind his hips, feeling him starting to harden underneath you. Oh God, the way this man moaned was purely sinful.
You groan and whimper, realizing you can't take this further, no matter how much your pussy is begging for him right now. You pull away with a teasing smile.
"Let's wait..." you say softly, passion still dotting your voice.
Miguel shows the slightest bit of disappointment but nods in agreement. "Of course." He sighs and gives your thighs a squeeze of reassurance.
"I'm starving." you say, tracing his neck with a finger.
He smiles. "Well, let's go fix that right now."
You two shared grilled cheese sandwiches from your favorite food truck and as you walked into your apartment, you admitted to yourself that you were falling.
On your second date, you casually mentioned a little white lie that you were on your period to hopefully keep sex off the table so you wouldn't have to have the tough conversation.
"Oh, are you sure you're feeling up to getting dinner right now?" Miguel asked as you walked side by side towards the small Mexican restaurant.
"Mhmm!" You replied cheerfully.
Miguel gave you a skeptical look but followed you into the restaurant.
It was one of those express food places where you ordered your food at the counter. When the cashier asked if you were eating here or taking it to go, Miguel abruptly interrupted,
"We'll take it to go."
You looked up at him, puzzled.
"You're not feeling well, we should let you rest at home where you're comfortable." He replied, taking your hand in his.
"Oh, right!" You smiled and nodded enthusiastically. You totally forgot you were lying. Your heart starting to pump quicker in anticipation when you realize he's coming over. Give me the strength, please, God.
----
After you two went back to your apartment and ate, you talked for nearly two hours about literally everything. Your childhoods, your complicated relationship with family, favorite foods, places you've always wanted to travel to, politics, even.
As soon as you cuddled next to him on your couch and got a whiff of his cologne, soon your tongue was in his mouth and he was on top of you, kissing you with so much tenderness you were actually contemplating marriage in your head.
He sighed a little into your mouth, letting his hands wander down to your ass. Your eyes went wide, but you continued anyway, continuing to lock yourself against his yummy lips.
Miguel groaned and moved to kissing your neck, your vision flashing as your eyes fluttered at the tempting sensation he was giving you.
"Not going to lie...I want you right now..." He whispered against your skin.
You whimpered. "I want you too....so much....but I'm on my period, remember?" Hoping he'd buy it.
He inhaled sharply at your words, increasing the intensity of his kisses.
"I don't mind..."
Dammit.
You feel your eyes water and before you know it, you're crying. Miguel pulls back, concern in his eyes.
"Did I hurt you...? What's wrong...?"
He presses the back of his hand against your cheek as one tear after another and another streaks off to the side of your eyes and into your hair, gravity causing them to run downwards as you're still pinned underneath him.
"I can't..." You choke out. "It's just something I need to tell you."
Miguel swallows and allows you to sit up. His eyes remain locked on you and scan your face for any inkling of what you're about to tell him.
Just drop the bomb now.
"I'm not actually on my period right now. I can't have sex with you right away because I need to tell you that I have an STI. It's Herpes Simplex Virus 2. I'll have it the rest of my life. I get occasional outbreaks in my genital region due to stress or if I miss a couple doses of my antiviral medication. I've had it for over 5 years now and it's quite manageable."
Miguel nods, his face in an unreadable expression. His eyes leave yours for just a moment as though he's starting to think quietly in his head.
You exhale shakily, the worst part is over, but continue with the facts which you've rehearsed many times.
"It's very common. As many as 1 in 6 adults may have it in the US, but many who do show no symptoms, as a result they might not even know they have it. But, I understand that you need to do what's best for you and come to your own conclusion about what I just told you. So if you choose to not continue seeing me, I understand." At the last sentence, your voice cracks a bit. "I like you a lot. I'm sorry for getting emotional..."
Miguel sits in silence for just a moment longer and he puts a hand on your thigh. "Thank you for telling me.... To be honest, I was expecting worse news than that. Like, you have a secret boyfriend I don't know about or... " He gives a little scoff, then looks at you, not moving his hand from your thigh.
"It's not the best of news, but it's not the end of the world. And it certainly doesn't define who you are. You're still you, and I've enjoyed getting to know you quite a bit and find myself liking you a lot too..." Miguel swallows. It's been a while since he's been this expressive with his feelings, but he feels he can venture a little outside his comfort zone since you're putting yourself in such a vulnerable position right now.
"I don't know much about Herpes myself. I'd like to educate myself more on this and then we can talk more about what we can do from here. Is that okay with you?" He asks, his voice gentle.
You nod, eagerly. The weight of the world had just been taken off your chest, you could breathe at last. He asks you a few more questions, like how often you take your medication, when you got diagnosed, how you manage your condition and so on. You answer honestly and firmly, pausing to gauge his reaction and make sure you explained yourself clearly enough. After talking for another hour or so, it's about 10:30 pm. You've definitely reached quitting time, and you're fighting to keep your eyes open.
You two share a long embrace before he walks out the door.
"Thank you, for a wonderful night and for dinner and being so understanding. I haven't always had the best response when telling people about this." You say into his chest, trying to hold him long enough his scent will stick to you after he leaves.
He smiles, still holding you. "You're welcome. Thank you for being honest and vulnerable with me. I'm kind of amazed at how much we have in common. I'll talk to one of my medical contacts some more about this. Don't be worried if I don't text you right away tomorrow. Then, we can talk more about what we'll do."
You nod, and after giving him one last kiss on the cheek, he leaves out the door and into the night. You watch him walk down the stairs and close your door with a soft click.
----
The next day, Miguel's at HQ speaking with one of the physicians in the lab.
"What are the different types of Herpes Viruses?"
The doctor leans against the counter and answers,
"There are two types of herpes simplex virus: HSV 1 and HSV 2. HSV 1 commonly causes oral herpes, or cold sores. It can show up as an upper respiratory tract infection during early childhood, whereas HSV 2 is the cause of most cases of genital herpes. However, it is possible for HSV 1 to cause genital herpes and HSV 2 to cause oral herpes."
Miguel nods and asks more questions.
"I ask because I started seeing a woman recently who has HSV-2. To my knowledge, I don't have it. What would that mean for us in terms of intimacy?"
The doctor nods and she answers,
"HSV-2 is mainly transmitted during sex through contact with genital or anal surfaces, skin, sores or fluids of someone infected with the virus. It can still be transmitted in the absence of symptoms. If you plan on being intimate, I recommend the use of condoms to decrease the risk of transmission. If your partner is also taking antiviral medication to suppress outbreaks, that helps decrease the risk of transmission as well. But, if your partner is having an outbreak or symptoms, I recommend abstaining from sexual activity until they resolve."
Miguel nods and takes in all the information the doctor is providing him, thanking her for her time.
He calls you, and you answer eagerly.
"Miguel?"
"Hey," he answers. You can hear the soft smile in his voice as he greets you. "Want to meet at Central Park in an hour? I figured we could go for a walk and talk in person. You don't need to be worried. I want to see where this goes with us, and now that the doctor gave me more information, I want to talk about it with you."
You feel your chest rise with hope. "Yeah, absolutely. I'll meet you in an hour. Thank you for taking the time to learn about it. You have no idea how much that means."
Miguel smiles. "Of course. You've been so patient with me, it's the least I could do. See you soon, get there safe."
"See you soon!" You hang up, and go get dressed.
---
The rain has started to come down a little bit, sprinkling and peppering the pavement in little dots, the earthy petrichor permeating the late spring air as the sky melts into a faded grey overcast with a thick layer of cloud cover.
You tuck your hair in your jacket hood, starting to jog a little faster to escape the falling raindrops as you approach Central Park. You see Miguel sitting on a park bench, across from the pond, totally unphased by the precipitation. You stroll awkwardly up to him, not sure where to look as you get closer to him. He hears footfalls approaching and turns, searching for the source and finally notices you, becoming slightly amused at your displeased reaction to the rain.
"Sorry, perhaps meeting in the park wasn't the best idea considering the weather," he says as he stands up, causing you to move your chin up a little to meet his tall gaze.
"Yeah, perhaps not." You huff.
Miguel grins and gestures towards some trees that will provide a little bit of shelter from the budding rain shower and you follow him there.
He leans against the tree, hands on his hips. "I talked to the physician. All in all, it sounds like a very manageable condition, which you've already covered with me. You're already taking antiviral medication daily." He clears his throat.
"But, when it comes to sex, we should use condoms. At least in the beginning to decrease the chances of transmission, and make sure you're feeling well and have no symptoms before we do anything. You've had the condition for long enough, I trust you that you're aware of your body and can pick up on whether or not you're about to have an outbreak. Do you have any thoughts on that?" He looks at you.
You nod. "I think that's completely reasonable. Thank you for trusting me, really." You lay your hand on his shoulder, giving it a small squeeze.
He gives you a small side smile in return. "Just so you know, I'm not expecting sex right away. I just bring it up now, in case we find ourselves in a heated entanglement like we did last night..." He kisses your hand. "We'll have already covered it and know what to expect."
You nod. "I definitely want to, at some point. But I'm in no rush either. We'll wait for the moment to present itself I guess?"
He grins and stands up from where he was leaning, letting both of his hands cup your face now, nothing but soft affection for you lining his pupils.
"Sounds perfect to me."
You two traded warm, lingering kisses as the rain poured a little harder around you, saturating the city of Nueva York, turning the trees in Central Park a vibrant, otherworldly green, the thunder shaking the sky in a deep rumble.
----
2 years later on a cruise ship gently coasting the Caribbean
The blinds were drawn around your ocean suite, giggles escaped you and Miguel as you gave him a playful shove back onto your freshly made bed after dinner, courtesy of housekeeping, both of you about four wine glasses deep.
His breath hitches as he watches you slowly hike your strapless maxi dress down your body, biting his lip when your tits bob out of your dress, practically drooling as though it's the first time he's laid eyes on you when the fabric slinks off the rest of your body, kissing your curves on the way down until it's laying in a heap on the floor, leaving you naked in front of him.
"Ven aquí..." (Come here) He whispers, pulling you closer as he sits on the bed, the noticeable glint of a silver wedding band with a small diamond embedded in the middle on his left hand.
He leans down and licks hungrily between the folds of your pussy. You sigh and close your eyes, using those beautiful broad shoulders of his to steady yourself, the twinkle of your own sizeable rock on the wedding band on your left hand catching in the dim light of the honeymoon suite.
The sound of his licks get more sloppy and wet as you drip more and more into his mouth, his tongue fueling the fire. "God, baby...."he groans, landing a sharp spank on your ass.
You gasp and buck your hips into him, pleasure sizzling in your core when your clit brushes against his nose. He pulls you in tighter to his face and you lift your leg, putting one foot on the bed to spread your pussy wider for him.
He scoots back instead, pulling you on top of him and directly over his beautiful face, his chest hairs poking out of his half buttoned dress shirt. He has one hand gripping your thigh and one squeezing your ass cheek as he continues to eat you out. "Lower, baby.." he whispers, tugging you downwards so you're sitting right on his face.
You feel your cheeks burn as you look at yourself in the mirror hanging above your bed on the wall. Completely naked and legs spread, riding your new husband's gorgeous face, his powerful large body pinned underneath yours.
One orgasm later, you're panting and sweating on the bed, looking up at the ceiling when Miguel gets back on top of you, planting a sweet kiss into both ankles as he brings them to rest on his shoulders. You look at him through half-lidded eyes that rake over his majestic form, his arm muscles rippling slightly as he gets into position.
He brings his cock to the entrance of your pussy, your ankles still perched on his shoulders, swirling the tip around the outside to collect any remaining arousal as lube. Both of you gasp at the same time as he slowly eases his cock inside you. That first thrust sends you straight to heaven and you release a satisfied moan. He sets a steady pace, fucking you in splendid, deep, strokes.
Your lips fall open and he traces them with his thumb while still rutting into you. You close your mouth around it, sucking and swirling your tongue around his thumb while you gaze into his eyes.
His own mouth falls open a little, lust blown pupils of his showing he's dangerously close to cumming as he lets out a deep moan.
"Fffuck, baby, you look so beautiful like this. Sucking my finger while your pussy takes my cock..." He purrs.
You let out a filthy moan in response, still sucking his finger while he drives his cock deep into your pussy with both ankles on his shoulders. He leans down to kiss you, letting your ankles fall to the side and back onto the bed, opening your thighs a little bit as you welcome his body in missionary. He tilts his head to the side a little bit, scarlet irises pulling you in, then kisses you gently as his body continues to make love to yours.
You savor the kiss, letting your tongue explore his mouth, the taste of your pussy lingering in it and bringing both hands to tangle themselves in his hair. He pulls away for just a moment for air, and you coo softly to him
"I love you so much..."
He exhales slowly, slowing down his strokes just a little but making them more deep and dramatic, causing a twinge of pain and pleasure to course throughout your veins.
"I love you, my wife. Forever."
You kept fucking deep into the night, tropical colors painting the sky as the sun dipped below the horizon, nothing but ocean air and the thrill of adventure awaiting at your destination.
Your diagnosis and any other obstacles remained long forgotten as you and Miguel entered forever with hands intertwined, still and all.
-----
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mindblowingscience · 2 months
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The virus behind the common cold sore could put people at greater risk of Alzheimer's disease. A long-term study of more than a thousand 70-year-olds in Sweden has now found those exposed to the herpes simplex virus type 1 (HSV-1) face double the risk of developing dementia. The association stuck regardless of the two strongest known predictors of Alzheimer's disease today: age and a genetic variant called APOE-4. The findings are the latest to suggest that some common viral infections may be a neglected source of cognitive decline.
Continue Reading.
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astralarya · 5 months
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If you are HSV positive (including having only "cold sores"), I highly recommend taking a daily antiviral. There is increasing evidence that HSV increases the risk of dementia or cognitive decline. However, antivirals seem to be protective against this outcome.
As an added bonus, you shed fewer viral particles and thus greatly lower the chance of infecting others—which can occur via casual contact like sharing food. Even when you are asymptomatic!
I've often found it surprising how few people are on an antiviral regimen given how common it is to be HSV positive (approximately 1 in 6 people age 14 to 49 in the US).
This 2021 review covers the evidence surrounding HSV's association with increased risk of dementia as well as "the apparent protective effects of treatment of HSV1 infection or of VZV infection with antivirals prior to the onset of dementia".
More recent study (2022) in the Korean population that shows increased incidence of dementia in individuals with HSV1.
Notable Nature paper (2021) which failed to find association with dementia. However, the authors still found an increase of "cognitive decline".
When the 2021 review says "overwhelming evidence", they mean it. There are many studies which have shown this association which I will not repost so check out their references if you are interested.
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drdemonprince · 6 months
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genuine question, I get why blaming people who have just caught covid for it is some fucked up victim blaming bullshit, and highly analogous to shaming ppl who've gotten an STI, but is it okay to assign blame/responsibility to people who *give* others covid? it seems to me that just like with STIs (particularly HIV and HSV bc they're not curable) its your responsibility as like, a person who has sex and isn't a total asshole, to do a reasonably good job of knowing whether you have these things, and then either give people who might catch it from you the ability to consent knowing that, or only interact with people in such a way that transmission is highly unlikely. In other words, having or getting an infection is morally neutral, but failing to break the chain of transmission isn't, especially when that failure results from complete inaction/ignoring the problem, as opposed to *attempting* to break it and failing due to factors outside your control. I've seen people saying that beleiving this is the same as slut shaming people who get STIs, and tbh that seems ridiculous to me, but what do you think? is "if you have covid and pass it on to someone, especially by going around in public without a mask, you are morally responsible for the harm the disease causes them" incorrect/going to backfire in some way I'm not seeing? I do get how the same statement about HIV is not good, but also you can't give someone HIV by eating in the same restaurant, so it seems like there are some important differences.
The passage on moralizing HIV transmission in Sarah Schulman's book Conflict is Not Abuse is a real stand-out passage in an otherwise (to me) highly underwhelming tome -- because Schulman has been involved in AIDS activism since its early days and is very conversant in the laws that have been used to incarcerate gay men and others for having the virus, and for supposedly passing it along to other people.
We can philosophize all we want about how wrong it would be for a person to knowingly go about infecting other people, but when we're actually dealing with how such matters go in the real world, it's not a useful moral or practical question. How do we know that someone knows they have the virus? Do we consider a person morally culpable if they have the sniffles but brush it off, not realizing it's something more serious? What about an Autistic person or trauma survivor with alexithymia, who is not closely attuned with their body states? If I can walk around with a bleeding gash on my leg for hours or a bloody UTI and not know it, I can have a mild cold and not know it. Am I too blame for spreading the virus then? What about someone who does know they have COVID but has no legal protections in their workplace and no financial support and determines they have no choice but to do a shift at the grocery store, because otherwise they'll be fired and at risk of homelessness?
These might sound like extreme examples, but we're talking about collectively millions of people's everyday experiences here. If a person is at fault for any disease that they spread, what then? What logically follows from that declaration? Should we make knowing transmission illegal? We've already seen in history how such a policy is used to terrorize and oppress gay men. It's an impossible thing to enforce, because someone's knowledge state is impossible to fully know or surveil, especially when we're not, you know, providing tests to anyone in any kind of systematic way, and in fact our government and most of our employers are actively discouraging us from testing or knowing too much.
Of course, I doubt that you actually want any kind of legal policy like that very much. I'm certain what you are really asking about is what responsibilities we should reasonably expect individual people to hold. And the answer is, well, look at how they are holding them now! Clearly people do not have adequate support at the moment to even be cognizant of their status. It's not a useful question. It just isn't. If we were providing free tests every day at major public access points and legally protecting people's rights to call off sick whenever they did test positive, and paying them lost wages, then we could talk about people being irresponsible and knowingly spreading a disease out of malice or laziness. but we don't have any of that, so we can't.
The solution to a population failing to take the "right" actions is always to look at the external factors that makes taking the right action hard. And right now? Being responsible surrounding covid is very, very hard. We can condemn every person who spreads COVID (or HIV) to another person morally all we like, but it's not going to save lives, and it's going to harm a lot of vulnerable people in the process, so why do it? Why not instead ask ourselves what we can do as a society to help make it easier for a person to behave in pro-social ways?
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positivesinglesdate · 2 years
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great-and-small · 1 year
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Your tags about the marmoset -- so the owner had HSV-1, which is endemic in humans and always present after a human gets infected and pretty much harmless except for the cold sores, and the monkey caught it from her and was dying?
How do zoos manage this stuff? Do human keepers always have to mask and glove up when handling any monkey?
Essentially, yep. My current research involves herpesviruses and I could talk for days about how they are the smartest virus. They have evolved with vertebrates for so long that many of them are extraordinarily host-specific. A herpesvirus that causes no symptoms in a pigeon can cause fatal organ necrosis in a great horned owl. This concern absolutely exists in primatology as well. There are subclinical herpesviruses in monkeys and apes that can kill a person, and our herpes can be dangerous to them as well. This is why contact with primates in zoos is very strictly regulated; it’s for everyone’s safety. In 2016 a zoo in Israel lost an entire family of saki monkeys to HSV-1.
In the veterinary setting, we always wear at least mask and gloves when interacting with any primate. It is important to note however that some primate species are far more susceptible to human herpesvirus infection than others, and the risk level is not the same across all primates.
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livingwithhsv · 2 years
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I’ve been quiet, grieving and healing.
I left my seven year relationship, which is never easy. It also means sharing my herpes status with potential new partners, which I wasn’t prepared for but I was finally put in the situation where I shared.
So here’s my tips on how I shared my status.
• Confidence is key.
• Don’t apologise, you have nothing to be sorry for.
• Keep it short and sweet but add a fact or two in there.
• If you use HSV explain what it means. (Most people don’t know)
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transgenderer · 11 months
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Virus latency (or viral latency) is the ability of a pathogenic virus to lie dormant (latent) within a cell, denoted as the lysogenic part of the viral life cycle.[1] A latent viral infection is a type of persistent viral infection which is distinguished from a chronic viral infection. Latency is the phase in certain viruses' life cycles in which, after initial infection, proliferation of virus particles ceases. However, the viral genome is not eradicated. The virus can reactivate and begin producing large amounts of viral progeny (the lytic part of the viral life cycle) without the host becoming reinfected by new outside virus, and stays within the host indefinitely.[2]
Episomal latency refers to the use of genetic episomes during latency. In this latency type, viral genes are stabilized, floating in the cytoplasm or nucleus as distinct objects, either as linear or lariat structures. Episomal latency is more vulnerable to ribozymes or host foreign gene degradation than proviral latency (see below).
Advantages of episomal latency include the fact that the virus may not need to enter the cell nucleus, and hence may avoid nuclear domain 10 (ND10) from activating interferon via that pathway. Disadvantages include more exposure to cellular defenses, leading to possible degradation of viral gene via cellular enzymes.[12]
Proviral latency: A provirus is a virus genome that is integrated into the DNA of a host cell
All interferons share several common effects: they are antiviral agents and they modulate functions of the immune system. Administration of Type I IFN has been shown experimentally to inhibit tumor growth in animals, but the beneficial action in human tumors has not been widely documented. A virus-infected cell releases viral particles that can infect nearby cells. However, the infected cell can protect neighboring cells against a potential infection of the virus by releasing interferons. In response to interferon, cells produce large amounts of an enzyme known as protein kinase R (PKR). This enzyme phosphorylates a protein known as eIF-2 in response to new viral infections; the phosphorylated eIF-2 forms an inactive complex with another protein, called eIF2B, to reduce protein synthesis within the cell. Another cellular enzyme, RNAse L—also induced by interferon action—destroys RNA within the cells to further reduce protein synthesis of both viral and host genes. Inhibited protein synthesis impairs both virus replication and infected host cells. In addition, interferons induce production of hundreds of other proteins—known collectively as interferon-stimulated genes (ISGs)—that have roles in combating viruses and other actions produced by interferon.[13][14] They also limit viral spread by increasing p53 activity, which kills virus-infected cells by promoting apoptosis.[15][16] The effect of IFN on p53 is also linked to its protective role against certain cancers.[15]
Another function of interferons is to up-regulate major histocompatibility complex molecules, MHC I and MHC II, and increase immunoproteasome activity. All interferons significantly enhance the presentation of MHC I dependent antigens. Interferon gamma (IFN-gamma) also significantly stimulates the MHC II-dependent presentation of antigens. Higher MHC I expression increases presentation of viral and abnormal peptides from cancer cells to cytotoxic T cells, while the immunoproteasome processes these peptides for loading onto the MHC I molecule, thereby increasing the recognition and killing of infected or malignant cells. Higher MHC II expression increases presentation of these peptides to helper T cells; these cells release cytokines (such as more interferons and interleukins, among others) that signal to and co-ordinate the activity of other immune cells.[17][18][19]
Epstein–Barr virus lytic reactivation (which can be due to chemotherapy or radiation) can result in genome instability and cancer.[5]
HSV reactivates upon even minor chromatin loosening with stress,[7] although the chromatin compacts (becomes latent) upon oxygen and nutrient deprivation.[8]
Cytomegalovirus (CMV) establishes latency in myeloid progenitor cells, and is reactivated by inflammation.[9] Immunosuppression and critical illness (sepsis in particular) often results in CMV reactivation.[10] CMV reactivation is commonly seen in patients with severe colitis.[11]
viral latency is so fucked up
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circumcure · 3 months
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How Adult Male Circumcision Improves Sexual Health
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Adult male circumcision, the surgical removal of the foreskin from the penis, has been practiced for centuries for various reasons, including religious, cultural, and medical purposes. Beyond its traditional significance, research has increasingly highlighted the potential benefits of adult male circumcision for sexual health. In this article, we’ll explore the evidence-backed ways in which adult male circumcision can enhance sexual health and well-being.
Reduced Risk of Sexually Transmitted Infections (STIs):
One of the most compelling reasons cited for adult male circumcision is its role in reducing the risk of sexually transmitted infections (STIs), including HIV. Numerous studies have demonstrated that circumcised men are at lower risk of acquiring HIV, herpes simplex virus (HSV), human papillomavirus (HPV), and other STIs compared to uncircumcised men. This is believed to be due to the decreased surface area and moist environment under the foreskin, which can facilitate the transmission and replication of pathogens.
Lower Risk of Penile Cancer:
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Adult male circumcision has also been associated with a reduced risk of penile cancer, a rare but serious condition that affects the tissues of the penis. The removal of the foreskin eliminates the moist and bacteria-prone environment that may contribute to the development of penile cancer. While penile cancer is relatively rare, circumcision offers a preventive measure that can lower the risk of this disease.
Improved Hygiene:
The removal of the foreskin through adult male circumcision simplifies genital hygiene and may reduce the risk of certain infections and irritations. Without the foreskin, it’s easier to clean the penis, as there are no folds or creases where bacteria and debris can accumulate. This improved hygiene can contribute to overall genital health and comfort, reducing the likelihood of unpleasant odors or infections.
Enhanced Sexual Satisfaction:
Some studies suggest that adult male circumcision may lead to increased sexual satisfaction and pleasure for both men and their partners. This is thought to be related to changes in penile sensitivity and sensation following circumcision. While individual experiences may vary, some men report heightened sexual sensitivity and improved erectile function after undergoing circumcision, which can positively impact sexual satisfaction and intimacy.
Reduction in Foreskin-Related Issues:
Uncircumcised men may experience foreskin-related issues such as phimosis (tight foreskin), paraphimosis (inability to retract the foreskin), or recurrent infections. Adult male circumcision can alleviate these problems by removing the foreskin entirely, eliminating the need for ongoing treatment or management of foreskin-related conditions. This can lead to improved genital comfort and function, enhancing overall sexual health and well-being.
Psychological Benefits:
In addition to the physical benefits, adult male circumcision may have psychological benefits for some individuals. For men who choose circumcision for personal or cultural reasons, undergoing the procedure can bring a sense of empowerment, confidence, and cultural identity. Feeling more comfortable and confident in one’s body can positively influence sexual self-esteem and relationships.
Conclusion:
Adult male circumcision offers several potential benefits for sexual health, including reduced risk of STIs, lower risk of penile cancer, improved hygiene, enhanced sexual satisfaction, resolution of foreskin-related issues, and psychological well-being. However, it’s important to note that circumcision is a personal decision, and individual experiences and preferences may vary. Before considering circumcision, it’s essential to consult with a healthcare provider to discuss the potential risks, benefits, and implications of the procedure. Ultimately, the decision to undergo adult male circumcision should be informed by careful consideration of one’s health, cultural beliefs, and personal preferences.
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unravelwithme · 5 months
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I HAVE HERPES
Yes, a very shocking first post I know. It’s usually a controversial hush hush subject. No one ever wants to talk about it or hear about it. It’s the punchline on tv, and an insult in real life. So of course no one talks about it. The stigma is so grand and scary, who would want to talk about it?
But we should talk about it! You know why? Because it is one of the most common infections to affect humans. More than half of the population has HSV-1 and around 13% has HSV-2. You could have herpes and not even know it. Around 90% of people infected are unaware that they have it.
It’s so unfortunate that people living with this disease have to live in silence. We hide for fear of being ostracized. Our romantic lives seem like a thing of the past. Pharmaceutical companies have no desire to find a cure because then they wouldn’t make money off antiviral medication, and no one talks about herpes so funding research seems pointless.
I am so fed up! No one talks about it, no one cares. I have to live my whole life suffering and fearing that I’ll never be loved. This condition has made me want to unalive myself on various occasions. The guilt eats you up.
But I do want to be a voice for those who struggle with the same issue. I want to be an educator as well, to help prevent future infections, and to humanize the people who live with this condition.
I’ll finish this post with some quick facts:
- There are two types, HSV-1 and HSV-2.
- HSV-1 is oral
- HSV-2 is genital
- You can spread herpes even without a sore present.
- oral herpes can cause genital herpes and vice versa though it is somewhat rare.
- Many clinicians are uneducated about the disease and spread misinformation.
- You could have herpes and not even know it.
- Testing is difficult because the test can often be unreliable.
- You may not even know until you have your first breakout.
- You may never have a herpes breakout though you have the condition.
These are a few facts I’ve accumulated while researching. I am open to corrections if something I said is incorrect or needs clarification. I will return with more information about this condition. I hope I can be there for those of you who are struggling with your diagnosis. We can get through this together!
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