#spport

[cancerabcs]

A New Standard of Care After Prostate Surgery

According to an international study led by Alan Pollack, M.D., Ph.D., chair and professor of radiation oncology at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, and published in The Lancet, adding short-term hormone therapy (ADT) and pelvic lymph node radiotherapy to standard of care prostatectomy surgical bed treatment benefits prostate cancer patients whose PSA levels are rising post-prostatectomy. 

According to Dr. Pollack, a rising PSA following prostatectomy for prostate cancer is a sign of a recurrence, which happens in more than half of men with negative surgical pathology. Dr. Pollack also said, "the PSA indicates that the cancer has returned, but it does not reveal where it is coming from — the prostate surgical bed, the pelvic lymph nodes, or elsewhere in the body."

Salvage radiation is the only curative option for such individuals, and the standard of care has been to treat only the prostate surgery bed. The SPPORT study (RTOG/NRG Oncology 0534) was designed to see if adding short-term hormone therapy or short-term hormone therapy plus pelvic lymph node radiation significantly lowers recurrence and the risk of cancer spreading.

The SPPORT trial, financed by the National Cancer Institute, included men from 283 radiation oncology cancer treatment sites in the United States (including Sylvester), Canada, and Israel who had prostatectomy but had PSAs ranging from 0.1 to 2.0 ng/mL. The men were randomly assigned to one of three treatments: prostate bed radiotherapy alone, prostate bed radiotherapy plus four to six months of hormone therapy (ADT) or the two treatments plus pelvic lymph node radiotherapy.

The researchers chose five-year independence from prostate cancer progression as their primary outcome for the various treatment arms. They discovered that there was an incremental advantage at each therapy intensification level.

The most intensive treatment, which included the removal of the pelvic lymph nodes and ADT, performed much better than the others. In an unplanned subgroup analysis based on PSA level at protocol entry, all the men improved significantly from the addition of ADT, regardless of their actual PSA numbers.

Five-year freedom from progression was 70.9 percent in the group that had only prostate bed radiation, compared to 81.3 percent in the group that also received ADT.

Adding pelvic lymph node radiation resulted in 87.4 percent patient benefit. Still, this advantage was most significant for individuals with higher PSAs at protocol entrance.

New Medical Standard of Care 

According to Dr. Pollack, the SPPORT trial validates and extends the findings of two prior randomized trials of prostate bed radiotherapy plus hormone therapy. It is the first randomized study to indicate additional benefits from the addition of pelvic lymph node radiotherapy.

Dr. Pollack indicated that the SPPORT trial findings are consistent with modern PET imaging modalities that show lymph node recurrences following prostatectomy are significantly higher than previously thought. The results set a new standard of care for salvage radiation.

#salvage radiation #AADT #ADT and Radiation #ADT #SPPORT #PSA recurrence

[semioticapocalypse]

Lothar Rübelt. Kampfball (Fight ball). Vienna. 1930s

Follow my new AI-related project «Collective memories»

#BW #Black and White #Preto e Branco #Noir et Blanc #黒と白 #Schwarzweiß #retro #vintage #Lothar Rübelt #Kampfball #Fight ball #Vienna #1930s #30s #spports #roof #rooftop

[prttykittes]

Uhhh...... Anyways, thanks for anyone supporting me through this crazy idiotic people who won't block me, (btw just a reminder I have no control which people read a my stuff, also I hope that person leaves me alone 💀)

#kittytail #thamks everyone but dont be weird #also to the other person #tjansk for your spport but ehhh... #fiction is not real #fiction is not reality btw

[warcrimesimulator]

I've long disliked liberals, and then I thought maybe I was being a little too harsh. They're well-meaning people, right? I'll follow these European liberals on Twitter because they support Ukraine, surely this will enrich my timeline and give me a very normal experience (biggest mistake of my life these are literally the most annoying people on earth and most of them are casually racist also)

#but yeah most of these people blindly spport Israel most of them jumped to support Azerbaijan as soon as it was relevant #it's just the opposite end of tankie campism #and don't even get me started on Russian liberals. they're just... lol. lmao.

[emmetrain]

Starter for @darkenedpunk061 !

The town of Spikemoth was not without its charms, as the pretty, vibrant neon lights were electrifyingly inspiring, but the people seemed a bit intimidating. Emmet would have adored the chance to let loose and be as energetic and intimidating as the townspeople if Ingo would have been there to keep an eye on him.

His research on the circumstances of his brother’s disappearance was not going anywhere, thus, when he was presented with the opportunity to free-ride to the Galar region, he begrudgingly agreed. There was no way Ingo would be there, though both he and Emmet had been huge fans of the Galar League.

With Elesa’s suggestions that resulted in Emmet being very uncomfortable, he was hopefully standing out less with the crowd (he doubted it). He put up the hood of the coat, and his coat was sloppily cropped to fit in with the fashion of Spikemouth. He donned a belt in pink and black which he bought on his way, his hair was up in spikes thanks to his little Joltik companion. Black eyeshadow was rubbed under his eyes to complete the look.

Once Ingo had safely returned home, Emmet was going to make him pay for everything, but especially for his Galar adventure.

At the end of his patience, he approached the nearest person with an awkward smile.

“Hi! I am Emmet. I am a Subway Boss from Unova. Is there anywhere people can hide? To avoid the others staring daggers at them, at least,” Emmet spoke loudly as his heart was aching for an affirmative answer.

Motioning with his hands a train that headed to a wall and raising his hands to show the explosion, he continued, “I am verrrry nervous, and would be grateful if you could show me the tracks to somewhere calm!”

#darkenedpunk061 #verse;; searching for the truth #ic #((Emmet and his emotional spport Joltik #((I ADORE DRAWING JOLTIKS OMG #((also *yeets a very nervous Emmet to Piers' town* please take care of him #((IF THEY BECOME FRIENDS many fashion designs await Piers #((Emmet is really inspired to design something new but he has to catch his breath first

[akuasucc]

im so sorry but people who only support players and go where they go is so annoyong

mbappe and messi stans specifically like yall are so annoying.. be serious and pick a team to support and stick with it

#a solo stan can never talk down on my club idc if the person u spport plays here

[littl-vs]

holy shit you can dislocate your kneecap??

#i think that's whats wrong with me #im thinking its a patellar (kneecap) subluxation (which is like an almost but not quite dislocation) #but.... repeatedly #all the time #no but like symptoms are chronic knee pain knee buckling and not spporting weight stiffness and swelling and creaking and/or cracking sounds #AND /AND/ when it happens the feelings are a buckling catching or locking of the knee and you wont be able to walk on jt #sound familiar????? CAUSE I THINK IT DOES

[the-corn-colonel]

What if there was like a WNBA for men

#besketball spports #sport

[sharsbitch]

triple AAA developers getting butthurt on twitter about how baldurs gate is an anomaly and shouldn’t set the standard for future games is just embarrassing.

“don’t expect games like BG3 to come out because they just got lucky”

larian is PASSIONATE as hell about this game, you can just tell how much they care in interviews. people should and will spport larian for their hardwork, for listening to player feedback, and for creating a great game!

#bg3 #kinda ranty #but seriously jealousy doesn’t look good on you babes

[gatioxd]

I WAKE UP AND

THNAK YOU GUYS SO MUCH FOR THE SPPORT U HAVE NO IDEA HOW MUCH I LOVE U GUYS AND MY MOOTS OH MY GOD IM GOIG TO STRNAGLE U (with love) AND DEE AHHHH AHHH AHH !!!!!! J!J! GO CHECK OUT @pandeesall HER ART IS GENUINLY SO FRSAKING COOL

#katz bullcrap #katz beautiful mootz #MWAH WMAH MWMA #KISSES #I OVE U

[intersexfairy]

I see we're sharing cat pics! This is Evie, she's one of the creatures ever and excellent emotional support for my wife!

OMG U HAVE A WHITE KITTY HOW PRECIOUS

i love evie! give her pets for me nd let her know she such good kitty for be emotional spport <3

#asks #cats #drunk posting

[luke-hughes43]

ok so we know how i said that stella and bella would play in the olympics for usa softball??

well now that have avery, she does too!

so ethan, dylan, and luke are all softball husbands and spport them in the 2028 olympics together!!!

#dylan x avery #stella zegras #bella murphy #avery johnson

[mm--chx]

It’s my first time posting here so

I lovewally and how he interacts whit the public. His appearance and clothes are very striking, really cute, a reason why i drew him. Even though i would like there to be more interaction or impact whit the spanish speaking community, i think it will have a lot of spport from the people.

Me encanta wally y como tiene una interacción con el público. Su apariencia y atuendos son muy llamativos, realmente lindo,una razón por la que lo dibuje. Aun que me gustaría que hubiera mas interacción o impacto en la comunidad habla hispana, creo que tendra mucho apoyo por parte de las personas.

#welcome home #welcome home fanart #wally darling #welcome home wally #welcome home arg #fanart #fandom

[ao3feed-tododeku]

#AO3 Link #FanFiction #AO3 Tododeku #💙 #💚 #Tododeku #♥ #A:Brokollitape #Quirkless AU

[galaxyspark-6e16]

honestly after the sheer stress factory that was hollow mind and edge of the world, labyrinth runners is a blessing; it gave gus more character development, willow and amity healing friendship, hexide embracing mltitrack and uniting aginst the emperor coven and golden guard status as of right now AND MORE IMPORTANTLY HUNTER  FINALL AS A GROP SPPORT AD TALKIG ABOUT HIS FEELINGS AND WE GOT HINTS OF BLSES AND OW SURUNDED BYY PEOPLE HECANN TRUST AAAAAAAAAAAAAAAAAAAAA what a rollercoster.

#THE OWL HOUSE #toh spoilers #my thoughts #gus porter #toh hunter #willow park #amity blight

[abbysan36]

🌸Full bpdy refe-🌸

🌺Minnie🌺

[Thanks for the spport]

#ocart #my oc art #artists on tumblr #artwork #digital illustration #digitalart #myart #ask me anything #oc artwork #goblin