#pre estrogen

[wikipediadogdotnet]

well. i missed them maybe a little bit. let’s never speak of this again

#I think estrogen would've fixed her tbh #aarmau #aphmau #fuckass webseries that changed my life #don't get me wrong I barely remember it at all . but the psychic effect this had on me as a pre teen was‚‚ something😭 #And it's the whole reason I started drawing . y'know I used to not draw noses bc the mc skins didn't have them💀 #and I couldn't draw any body proportion that wasn't like. skinny child? it was sooo sad #whateverrrrr. I'm done forever now #🦐 posts #🦐 art

[cloversposts]

It’s been 21 weeks since I started T, and my body finally looks like it did pre-“E”. (I say E in quotation marks, because I should have been on bioidentical estradiol and I should have been prescribed progesterone, but instead, i was given birth control to treat my condition, and it never fixed anything, and actively made my problems worse as well as made new problems.)

My hair has grown back— I have thick and long and denser leg hair, visible without my glasses on looking down at myself; my bush is fuller; my stomach and chest hair are back, albeit still soft and fine; and i have to shave my face every day again. Before I got on T “again”, i had to shave every other day. (“Again” in quotes because I'm intersex and have a large amount of T and androgen, and almost no estrogen and literally no progesterone, despite estrogen-based gestation. Like it was 0.5ng when it should have been at its highest.)

People interested in going on estrogen: it DOES change your body hair! It will soften and recede. It might not all go away, but i didn’t realize how much disappeared from my body (coverage and coarseness-wise) until I started going back on T and noticed how much it had changed from my younger age. I hadn’t been in a place mentally to track the difference, and since I wasn’t on proper hormones of any kind, it was gradual enough that I didn’t notice. But it may be different for you!

For other changes I’ve noticed, bottom growth is still significant and my voice is still cracking but doesn’t seem to be changing drastically. I haven’t pushed it very far but i am doing my best to practice my upper range when I remember, so I don’t lose it. I’ve been too afraid and dysphoric to fully test out my lower register.

Hope you all had a lovely weekend.

#hrt #testosterone #estrogen #estradiol #intersex #trans #queer #i tagged as estrogen because all of the changes I am experiencing are because I was on Estrogen for a while! #I wasn't on 'proper hormones' because no one tested my levels! ever! and i had serious signs of too much estrogen. #i am basically back where i started pre-hormone therapy at this point in time #plus some growth and some voice changes I don't want #and I may go back on E as well!

[chrissy-kaos]

It's that time. Shot #45493721.. It's weird to me that other girls don't share their experiences with hrt. If you have any questions and I can help dm me.

Disclaimer syringe is for HRT (hormone replacement therapy)

#hrt journey #trans hrt #hrt diary #mtf hrt #hrt #hrt estrogen #pre op mtf #mtf hormones #hormones #mtf positivity #mtf #mtf trans #mtf women #trans pride #transgender #transgirl #transisbeautiful #maletofemale #trans #girlslikeus #transformation #transwomen #trans fem #trans girl #trans goddess #trans positivity #transfeminine #transfem #trans woman #transition

[sombraluna]

If I see a girl with brushed-out curly hair and an aggressive side part covering most of her face I simply know that is a transgemder. Doesn't matter which way im psychically linked I get a little ping on my radar

#i know what you are #Trans #Transmasc #Transfem #nonbinary #Queer #Youre either pre ftm or 6 months of estrogen transfem

[thatonegreekgoddess06]

Transition Timeline - Entry 0, 1 month until estrogen- 12/9/22

I will be getting on estrogen in about a month and I decided to get a tumblr to use as a transition timeline. This is my pre-HRT selfie, No face just because I believe in internet safety and don't like it being on the internet.

#transfem #transgirl #pre hrt #estrogen #transgender #transition timeline #trans

[biblicallyaccuratefaggot]

twirl hair hiiii do you have a workout routine or are you just naturally beefy and strong? 😳🤭

i personally do a lot of curls, overhead presses, floor presses, all with some dumbbells. no specific routine, just what i feel like doing that day. oh and i do a lot of squats and sometimes pushups.

#pre-estrogen i was naturally really muscular but lost a lot due to going on hrt #my arms are somewhat back but i would like for them to be bigger i think #but its saying a lot that i have to do this much just to stay at where pre-e me was at just from sitting around #my peak buffness was from when i was in construction and frequently having to lug a bunch of 100lb cable reels up 8 floors

[blessedblissfulbroadcast]

7 Foods to Boost Estrogen Levels During Menopause

#menopause #health #hot flashes #sleep disorder #bone health #estrogen #boost #tw ed diet #diet #exercise #holisticwellness #wellness #foods #pre menopause #post menopause #mental health #joint pain #night sweats #Menopause symptoms Menopause relief Managing menopause Hormonal changes Women's health Hot flashes Night sweats Mood swings Menopause remedi

[transitjournal]

50 Days HRT Update 🔥

No, HRT will not make you turn to a cute anime girl instantly but it will surely do you these things.

Estradiol Hemihydrate 2mg/ Cyproterone Acetate 50mg

First of all, thank you all for your support and interest on my blog. It's what keeps me going.  💕

I used to take DIY HRT with different medications 2 years ago, with spiro and E2 valerate from January 26 2020 to late July 2020. Those doses were pretty low, at least considering from my point. And after I had to stop those meds, all my changes are rolled back, except some very very little breast growth. Now that I'm seeing doctors since October 2021, since HRT is gatekeeped in my country. Thankfully, I finally got them in July 25, officially got a prescription and had my legit cocktail! Now, of course I'm done with talking, let's move to the changes :)

Physical Changes

My skin is much more thinner and more translucent, and I'm more prone to bruises or tear even by slight contact with something. I feel that I have less tolerance for cold, that I now have to run my air conditioning in higher degrees. IDK what will happen in wintertime though! I've noticed my penis is also getting slightly smaller, as well as my testicles, since there's no T supplying those tissues anymore. No longer have to deal with morning wood or random erections, and this makes me so happy! I've noticed tucking is slightly easier because I can't get erections easily, and probably because of my testicular atrophy. I have small breast buds developing much faster compared to my old cocktail in 2020, (check my old posts if you'd like to get to know more about) the sad thing is since I'm taking single estradiol pill a day, fluctiations of estrogen affects my breast tissue. Sometimes it's like it's not there at all, and sometimes it's noticeably there (like a preteen girl's breasts, to compare).

My facial hair is slightly thinner, but it's still there and I have to shave everyday. The thing I didn't expected is, the growth pace of my facial hair is slowed considerably. Considering laser hair removal in future months, I'd do now but I'm short on cash nowadays. I always hated my facial hair, and it was (and still) my biggest cause of dysphoria. I've heard HRT makes laser hair removal on facial hair much more effective, so that's why I've been waiting around. I am also happy that, my scalp is less oily as well as my skin. I've had like soo much oily skin that I had to use lots of products to get rid of. My acne on my forehad is 90% gone, and I'm so happy for it.

Because of T reduced on my system, the sebum production is decreasing, making my skin dryer. And I tried to masturbate twice in a month, but it was so hard to reach climax. I guess I need to find different ways to please me. But my orgasms were more like a full-body experience, and it was... mind blowing.

Mental Changes

Okay don't be afraid of those negative things I say first cause they're not always here, haha. PMS symptoms, usually once a week (sadly). Cramps on my intestines to the point I can't move. Sometimes I find myself that everything in the world irritates me.

And my love life started to bloom again... at least from my side. I find myself I'm falling for handsome guys much more easily... I can't stop myself. It's more of emotional than sexual this time. I started to be able to cry again after months, I cried for my breakup with my boyfriend for first time after 3 months, why it happened is another story to tell about.

And I cry on emotional scenes in TV series. But being able to cry makes me feel free! 💕 I don't have specific craves to foods, but sometimes I feel hungry out of nothing... it's harder for me to say "no" to some foods. My emotions now feels like a rainbow.

#transgender #mtf #estradiol #estrogen #transgender hormones #mtf hormones #mtf hrt #trans girl #trans woman #lgbt #pre op trans #trans #transisbeautiful #queer #lgbt representation

[skyblue424]

Daily body pic :)

#trans hrt #hrt estrogen #mtf hrt #hrt journey #hrt #mtf trans #mtf girl #trans mtf #pre op mtf #mtf #transgender #transfem #trans women #m2f transgender #trangender #trans positivity #trans fem #trans femme #trans girl #trans healthcare #trans pride #trans stuff #trans selfie #transfeminine #transfemme #transgirl #trans

[foolstemper]

Realizing I’m a guy was so funny for me because it was like, “Fuck! I get to stop shaving for real!” Like that was the perk that stood mountains above the rest because it didn’t require intense stuff like surgery… just to realize I now have to constantly shave my face because it grew in, yeah, but it grew in different colors. My sideburns are darkish brown, darker than my hair. My cheeks grew in a mid neutral blonde dirty dishwater color. The hair above and below my lips are almost entirely translucent somehow and the hair under my chin and on my neck is dark as shit and I’ve developed a fear of my entire face ballooning up from an allergic reaction to hair dye - so shaving is required if I don’t want to look in the mirror just to point and laugh. Also tell me why it grows at different paces. I swear I was Frankensteined together. The colors are too different, man, but the bright side is: having to shave my face is pretty cool.

#personal #also my doctor said I’ve got some ~intersex problem~ TO QUOTE HER which was why I had a beard pre t #or like a really thin and soft beard pre t #probably also explains why t did almost nothing for me #bc there wasn’t much to do that it could do #I had low e for a female and high t for a female #now I have no hormones in me and it sucks trying to find a doc who can talk to me about options #bc I don’t want to do a normal dose of t #but I’m scared of estrogen and progesterone bc my surgeonssssss left too much breast tissue on one side #so I scare #idk I need a trans educated doctor #idec if they’re fucking nice I just need help

[catboybiologist]

“As a biologist, the terms biological woman and man don’t make any sense to me” okay then you’re an idiot and a terrible biologist. I swear to god, morons like you only become biologists just so you can hold it over others, when in reality, if biology deniers like you can become biologists, then being one really doesn’t mean much anyway. But this probably just gave an autogynophile like you a boner to read, anyway.

Oh fun! Haven't gotten one of these in a while. Disregarding the fact that you somehow think the qualification for being a biologist entirely hinges on defining womanhood, I do need to ask some clarification. I know I'm feeding the trolls here, but here we go: does your definition of "biological woman" mean:

Sociological woman? Eh, context dependent, I'm not fully out of the closet, but oftentimes, I am and present femme. So let's call that one 50/50.

Psychological woman? Because I am one.

Neurological woman? Because I am one [1].

Physical woman? My soft tissue redistribution is handling that well.

Hormonal woman? My blood tests are within cis female ranges.

Transcriptional woman? As a signalling molecule, the downstream effects of estrogen have broad transcriptional effects, completely changing the profile of gene expression and functional genomics of my cells. [2]

Genetic woman? I mean, see my above point- as far as my genes that are actually active, I have all of the same transcripts being produced, controlling which genes are expressed.

Karyotypic woman? I actually have a few signs pre-HRT that might point to a non-XY chromosome pair, but I haven't had a karyotype. We'll put that down as unknown. And hell, even if its XY, there's plenty of cis women who are karyotypically XY, with suppressed sry or complete androgen insensitivity. Interestingly enough, a completely androgen insesitive woman can go her whole life without knowing- and functionally, is very similar to a trans woman, actually. Fancy that. [3]

Reproductive woman? I can't produce an egg cell, but neither can significant fractions of cis women. Also, this is all gonna change soon, which is fun. [4]

There's also a lot of understudied aspects to the biology of HRT and even pre-HRT that are emerging, largely demonstrating widespread cellular and genetic remodeling of trans individuals undergoing hormone therapy. The field is a bit behind due to constant political pressure to revoke funding, but a lot of the results are extremely exciting in both testosterone and estrogen hormone therapies. I'm sure that, as a self professed biology As someone who presumably has a lot of expertise in biology, I'm assuming that you're aware of all of this cutting edge research, and are keeping up with modern papers, including but not limited to these cool findings:

Trans men on HRT exhibit significant genetic and transcriptional changes that make them biochemically male. [5][6]. It's a good hypothesis that the same happens with estrogen treatment, but those studies don't exist yet- I'm sure you're reserving judgment until more publications exist, of course.

Trans men on HRT develop male cell types and tissues. [7]

Trans women experience muscular and blood cell changes that align with cis women moreso than cis men [8]

And many, many more! This is an exciting, underserved, and groundbreaking field of research, and I'm sure you're keeping up with the latest in scientific journals about it.

I'm sure, of course, that you understand that it becomes impossible to draw a distinct line anywhere in here, and that words like "woman" are shorthand for the myriad of traits that invisibly synthesize in our mind and in society to represent a concept? I'm sure you understand that science is fundamentally descriptive, not prescriptive? I'm sure that you understand that these findings, while really cool and interesting, actually don't mean jack shit about what the word "woman" means or not?

As someone who is the ultimate decider in what a biologist is, I'm sure you know that bioessentiallism is a childish mindset that completely ignores and disregards the constantly changing, dynamic nature of biological systems, something that extends well beyond biological sex and its relation to gender.

I'm sure that also, that you understand that beyond just this, that the role of science in society is to advise how to achieve our moral principles, not create moral principles in themselves. And I'm sure that understanding means you know that trans affirming healthcare and supportive societal treatment leads to reduced mortality and increased happiness for everyone, right?

So great to talk to someone who is surely a scientist on this. You are a biologist, if you're talking like this, I assume? I assume you're not going to spit complete misreadings of scientific language from the background sections of these papers that only reveal you've never read a scientific paper in your life if you're thinking this way? I assume you have experience interpreting data like this?

Also, imagining my genitalia while writing this? Ew. Please stop projecting your fetishes into my inbox.

Works cited:

Kurth F, Gaser C, Sánchez FJ, Luders E. Brain Sex in Transgender Women Is Shifted towards Gender Identity. J Clin Med. 2022 Mar 13;11(6):1582. doi: 10.3390/jcm11061582. PMID: 35329908; PMCID: PMC8955456.

Fuentes N, Silveyra P. Estrogen receptor signaling mechanisms. Adv Protein Chem Struct Biol. 2019;116:135-170. doi: 10.1016/bs.apcsb.2019.01.001. Epub 2019 Feb 4. PMID: 31036290; PMCID: PMC6533072.

Gottlieb B, Trifiro MA. Androgen Insensitivity Syndrome. 1999 Mar 24 [Updated 2017 May 11]. In: Adam MP, Feldman J, Mirzaa GM, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2024. Available from: https://www.ncbi.nlm.nih.gov/books/NBK1429/

Murakami, K., Hamazaki, N., Hamada, N. et al. Generation of functional oocytes from male mice in vitro. Nature 615, 900–906 (2023). https://doi.org/10.1038/s41586-023-05834-x

Pallotti F, Senofonte G, Konstantinidou F, Di Chiano S, Faja F, Rizzo F, Cargnelutti F, Krausz C, Paoli D, Lenzi A, Stuppia L, Gatta V, Lombardo F. Epigenetic Effects of Gender-Affirming Hormone Treatment: A Pilot Study of the ESR2 Promoter's Methylation in AFAB People. Biomedicines. 2022 Feb 16;10(2):459. doi: 10.3390/biomedicines10020459. PMID: 35203670; PMCID: PMC8962414.

Florian Raths, Mehran Karimzadeh, Nathan Ing, Andrew Martinez, Yoona Yang, Ying Qu, Tian-Yu Lee, Brianna Mulligan, Suzanne Devkota, Wayne T. Tilley, Theresa E. Hickey, Bo Wang, Armando E. Giuliano, Shikha Bose, Hani Goodarzi, Edward C. Ray, Xiaojiang Cui, Simon R.V. Knott, The molecular consequences of androgen activity in the human breast, Cell Genomics, Volume 3, Issue 3, 2023, 100272, ISSN 2666-979X, https://doi.org/10.1016/j.xgen.2023.100272. (https://www.sciencedirect.com/science/article/pii/S2666979X23000320)

Xu R, Diamond DA, Borer JG, Estrada C, Yu R, Anderson WJ, Vargas SO. Prostatic metaplasia of the vagina in transmasculine individuals. World J Urol. 2022 Mar;40(3):849-855. doi: 10.1007/s00345-021-03907-y. Epub 2022 Jan 16. PMID: 35034167.

Harper J, O'Donnell E, Sorouri Khorashad B, McDermott H, Witcomb GL. How does hormone transition in transgender women change body composition, muscle strength and haemoglobin? Systematic review with a focus on the implications for sport participation. Br J Sports Med. 2021 Aug;55(15):865-872. doi: 10.1136/bjsports-2020-103106. Epub 2021 Mar 1. PMID: 33648944; PMCID: PMC8311086.

#cw transphobia #biology #basic biology

[paper-mario-wiki]

if i was put in a fighting game i would want a separate character that was a clone fighter of me, and that clone fighter just being me pre-transition.

this thought came about because i was thinking of what my palette swap costumes would be and i think i have too many outfits that i consider to be iconic from when i was still estrogen deprived.

#text #random thought

[gerardpilled]

did you guys see there’s drama in the hardcore community because a vocalist for a band admitted to being obsessed with a married woman and that he’s been dosing her husband’s pre workout drinks with estrogen for months so that he (the vocalist) would look more alpha male in comparison

[hellyesbro]

I was wondering if my coworker knew I was trans and he came up to me today and randomly went "You hear about that hardcore band that kicked out their lead because he was putting estrogen in his friends pre-workout" so I think he knows

[thebibliosphere]

I’ve been playing around with trying new foods for my MCAS recently and I’m happy to report it now looks like I can tolerate lemon again in very small quantities, which is a huge deal because citrus is a histamine liberator and I was pre-menstrual (estrogen raises histamine) and we’re in the middle of peak pollen season where I am, and it didn’t cause a flare up.

I was also able to handle cut strawberries over the weekend without my fingers blistering with hives, so that’s a big improvement too.

Then today I tried a tiny piece of gluten free cupcake for the first time in four years (made using rice flour, tapioca starch, xanthum gum and powdered cane sugar) about an hour ago and my throat didn’t swell like it used to, so that’s promising :D

#chronic health tag #MCAS #food mention

[lilithtransrights]

You ever had that moment pre transition where you'd look in the mirror randomly while brushing your teeth and you could just see the girl you were meant to be?

Like no dysphoria just being like "Yeah I could be hot if I took some estrogen"

#transgender