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man okay so I used to play mechquest and dragonfable back in like, 2008 when I was a kid with very little patience to follow a storyline. coming back as an adult and finishing mechquest has absolutely slapped me silly with how deep and serious the story is in between all the absurdist humour. I have. so many emotions over the whole storyline, and especially so many thoughts about the unique form of tragedy that is The Reset.
You save the world but it's not the world anymore. You and your friends survive but you don't know each other anymore- have nothing left of the lives you fought to keep. You 'save' everything but it's still all gone. Everything you knew and loved, gone, and you don't even know what you've lost. You can't even keep the memory of what you had- and that's almost kinder compared to being one of the 3ish people who DO remember... and have to live around everyone else who doesn't, knowing their closest friends look at them and see a stranger, and that they may as well be because they aren't that person they remember being.
And to top it all off, that terrible sacrifice doesn't even end it. you're still left fighting impossible and devastating wars over and over. It's the tragedy of doomed time loops with extra layers of devastating all over the place. The GEARS University students being forced to become soldiers because they're all that's left to protect their homeworld. The horrors of the Shadowscythe virus taking over friends and loved ones you may be forced to put down to save yourself. The town of Falconreach burning over and over because no matter how hard they fight, it's never enough. The people like Sha'rae who sacrifice themselves to try and prevent tyrrany from seizing power, only for it to be utterly useless.
Anyway the brainrot is severe and especially dangerous since I'm coming into exam season and all my hyperfixated brain wants to do is chew on glass about these games.
When you're a tiny nematode, electrical fields are positively uplifting. Literally.
The most famous nematode of all – Caenorhabditis elegans – has been caught using electrical fields to its advantage. The tiny worm can somehow piggyback on electrical fields to jump a surprising distance, across a petri dish, for example, or onto the back of a bumblebee for a ride to a new locale.
It's not entirely clear how the nematodes do this, but thanks to an experiment led by biologist Takuya Chiba of Hokkaido University in Japan, it's now apparent that these tiny animals use electrical fields to disperse far afield into new habitats.
"Pollinators, such as insects and hummingbirds, are known to be electrically charged, and it is believed that pollen is attracted by the electric field formed by the pollinator and the plant," says biophysicist Takuma Sugi of Hiroshima University in Japan, co-senior author on the study.
people who work/study in quantitative bio-adjacent fields, rise up. computational neuroscience where you get to see someone's thoughts in feelings in graph form??? so cool. biophysics where you can pass blood plasma through an electric field to determine whether a patient has cancer or not?? unbelievable. biomedical engineering where you can literally build a device to pump someone's heart and be the difference between their life and death??? oh my god. disease modelling, being able to predict AND prevent communities being affected by disease on a large scale through your analysis of data??? i love science
yes I do. I love physics. I love it bc I was raised by a brainiac engineer mother who taught me to see math as fun from a very young age. and sometimes it pisses me off bc I don’t understand concepts immediately and my ego is HURT but then I humble myself and learn it and I’m back to adoring it again
It took almost 4 years, but the fruits of my postdoc research are finally here! In our paper (with me as the first author), just published in Nature Communications, we decipher a working mechanism of an antibiotic that targets the membrane of bacteria in an unprecedented way!
enhanced PDF: https://rdcu.be/dgj2d
web version: https://lnkd.in/eRpxr4jg
And how does it work?
The antibiotic AMC-109 first self-assembles into stable aggregates with a cationic surface. These aggregates then specifically target bacteria cells and insert into their membrane.
You can see the process how we simulated it in a computer on the figure below. Grey-Blue is the antibiotic, Red-Yellow are lipids that together form a membrane.
@jmelcr did this awesome simulation work! You are an amazing scientist, jmelcr! I love you and it seems our collaboration did not ruin our marriage. Not yet, anyway 😄.
After insertion into the bacterial membrane, the antibiotic dissolves membrane nanodomains affecting membrane function without formation of any pores or holes in the membrane.
Below is the series of high-speed atomic force microscopy images that shows the process of dissolution of membrane nanodomains. Yellow are the membranes extracted from bacteria laying flat on a hard surface (black). The membranes contain nanodomains (bright yellow) that are important in living bacteria for its survival. Addition of antibiotic dissolves them.
More studies will follow that use this new target in bacteria giving us an advantage over untreatable superbugs. I will keep you posted. And... keep your fingers crossed. It's research after all, so we never know if and how well it's going to work.
Chilumi hc: Lumine is the only one that can sneak up on Childe. Her steps are almost feather-light and soundless, he doesn't even feel her presence when she's behind him.
And she jump scares the sh*t out of him. Every time.
You're just a drop out. What makes you think you know better than the people with masters and phds in physics as well as female politicians like AOC who are taking this seriously and investigating it? Once undeniable proof is presented that aliens are real (which will happen soon) will you accept the truth or will you double down like covid deniers? Real intelligent people stay open minded and wait for evidence before dismissing an idea. You're not a scientist or smart you're just an immature girl with a minimum wage office job.
this is the funniest ask i have gotten in a long time. out of all the stuff i have said and believe, what gets the most riled up hate anon in a long time is me saying the government isn't hiding alien bodies and spaceships 🤣🤣
just found out what i've been calling a midterm is a bit different and the grades we get on it are functionally useless and won't be written anywhere! yippie!!!
Already made similar post but I want to create scientist OCs so badly, but don't want to look deeply into different branches of science to figure out which one they should specialize in because I've been in a wikipedia rabbit hole of sciences, some of which I didn't even know existed, for days now and yet I have absorbed none of the information nor come closer to a conclusion, Carlos, give me strength, you're all just gonna be last name the scientist, you're specializing in the science of science, I swear, aahhh
Think of a monarch butterfly, and a distinctive image pops up: black-and-orange wings, with a sprinkling of white spots around the black edges. Those white spots may actually help monarchs complete their long-distance migration by altering the air flow around their wings.
Or, at least, that's the provocative new claim from a team of researchers that has analyzed hundreds of monarch wings collected along its migration route.
"If you have larger white spots, you're simply more successful at reaching Mexico," says Andy Davis, a researcher at the University of Georgia.
He and his colleagues believe that the pattern of color could interact with sunlight to create subtle temperature differences on the wing that can alter airflow, easing the butterflies' flight.