#atpase

[sciencesolutions]

#skeletal #disc #Solutions #myosin #actin #filament #atpase #masking #activates #science

[r-sensei]

ATPaseは回転してATPを作る。

#ATPase

[whats-in-a-sentence]

The energy used to drive these processes is supplied by different H+-pumping ATPases on these membranes (Figure 24.22).

"Plant Physiology and Development" int'l 6e - Taiz, L., Zeiger, E., Møller, I.M., Murphy, A.

#book quotes #plant physiology and development #nonfiction #textbook #energy #proton pump #atpase #plant cells #vacuole #cytosol #apoplast #plasma membrane

[tenth-sentence]

In particular, the guard cell proton-pumping H+-ATPase plays a central role in the regulation of stomatal movements (Figure 16.25; see also Figures 10.6 and 10.7).

"Plant Physiology and Development" int'l 6e - Taiz, L., Zeiger, E., Møller, I.M., Murphy, A.

#book quote #plant physiology and development #nonfiction #textbook #guard cells #proton pump #atpase #regulation #stomata

[uncrossedrhyme]

Creative Potential, Brain Electricity, and Hormonal Influence (PREVIEW)

The brain's steady electric potential, influenced by hormones and the environment, regulates mental function and shapes global consciousness

The following is a preview of a Patreon-exclusive newsletter. Click the icon below to support Become Something New for the cost of just one cup of coffee per month for access to this and upcoming Patreon-only content. ☕📖🧠💪 Patreon […] The physiologist Natalia Bekhtereva pointed out that pathological emotions disrupt the brain’s extremely delicate and complex network of steady electrical…

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#alexander bard #ATPase #biohacking #Childhood #conspiracy #cosmology #creativity #dailyprompt #dailyprompt-1893 #developmental psychology #dha #diet #docosahexaenoic acid #empathy #endotoxin #futurism #gaba #gut health #haidut #Health #hippocampus #imagination #katharina dalton #lipopolysaccharide #mental health #mitochondria #neuroscience #Nutrition #omega 3 #polyunsaturated fat

[kylejsugarman]

that one scene where walt's just verbally tearing down jesse with every awful thing u can imagine is obviously horrific but him saying "and how long before u start using again??" is so especially evil. because he Knows it'll get to jesse and make him feel insecure in his own tenuous sobriety, but worst of all, it'll use their moment of closeness and support in the shooting gallery after jane died against jesse to make him feel bad. walt found him there and took him to rehab in what seemed like an act of grace, of genuine concern, but now he's basically telling jesse that walt never had any faith in jesse's ability to stay sober or better himself. it meant Nothing. this moment where jesse believed he was dragged from the brink of death by someone who actually cared about him, who actually might love him—it was a charade. walt's not just currently withholding affection and approval to hurt jesse and get what he wants, he's poisoning past affection and erasing any hope jesse might have had that somebody believed in him.

#syd squeaks #'how long before u start using again' ill inhibit the na+-ca2+ atpase pump in ur cardiomyocytes and stop ur heart i mean it #breaking bad #walter white #jesse pinkman #walt weaponizing jesse's addiction against him hurts me so so bad. its so fucking evil

[kanopimembranemalang]

Canopy Membrane

Tenda membrane atau dengan nama lain, Canopy membran, Awning membrane, Tenda layang, Tenda kelelawar. Tenda dengan kombinasi material membrane yang fleksibel dan kuat dengan struktur rangka yang modern dengan menggunakan sistem tarikan seling, tenda membrane ini mampu menciptakan sebuah bentuk desain yang unik,fleksibel dan nilai artistik yang tinggi.

#konstruksi atap membrane #membran atap bitumen #membran atap bocor #membran untuk atap #membrane atpase #metode pemasangan atap membran #pekerjaan atap membran #rangka atap membran #spesifikasi atap membran #struktur atap membran

[science-lover33]

🧪The sodium-potassium pump🧬

Greetings, Tumblr community! 🧠💡 Let's engage in a comprehensive exploration of the sodium-potassium pump, dissecting its molecular intricacies and elucidating its critical role in cellular homeostasis.

Introduction:

The sodium-potassium pump, residing within the cellular membrane, is an adenosine triphosphate (ATP)-dependent transmembrane protein pivotal for maintaining ionic balance. Its primary function is to actively transport three sodium ions out of the cell while concurrently importing two potassium ions.

Functional Mechanism:

In terms of mechanistic precision, the sodium-potassium pump operates as an ATPase enzyme, utilizing the energy derived from ATP hydrolysis. This primary active transport process involves sequential conformational changes within the pump's structure.

The process commences with the binding of intracellular sodium ions to high-affinity sites on the pump. Subsequent phosphorylation, facilitated by ATP, induces conformational alterations that render the pump receptive to extracellular potassium ions. This triggers dephosphorylation, allowing potassium ions to be released intracellularly.

This orchestrated ion exchange serves to uphold the electrochemical gradient across the cellular membrane, establishing and preserving the resting membrane potential. In essence, the sodium-potassium pump is the architect of the delicate balance between sodium and potassium concentrations.

Physiological Significance:

The physiological ramifications of this meticulous ion transport extend to neuronal excitability and osmoregulation. By contributing to the establishment of the resting membrane potential, the pump plays a pivotal role in regulating action potentials and facilitating the propagation of nerve impulses.

Additionally, the pump actively participates in cellular volume control through osmoregulation. Its influence on water movement prevents cellular swelling or shrinkage, underscoring its significance in maintaining cellular integrity.

For those seeking empirical validation, consider consulting the following authoritative sources:

1. **Alberts B, Johnson A, Lewis J, et al.** Molecular Biology of the Cell. 4th edition. New York: Garland Science; 2002. Section 11.3, The Plasma Membrane.

2. **Nelson DL, Cox MM.** Lehninger Principles of Biochemistry. 7th edition. New York: W.H. Freeman; 2017. Chapter 11, Active Transport and the Cytoskeleton.

3. **Lodish H, Berk A, Zipursky SL, et al.** Molecular Cell Biology. 4th edition. New York: W. H. Freeman; 2000. Section 15.1, The Transport of Small Molecules Across Membranes.

Immerse yourself in the scientific intricacies of cellular dynamics with these foundational resources! 📚✨

#science #biology #college #education #school #student #medicine #doctors #health #healthcare #nursing #nurses #nurselife #human physiology #physiology

[aphidoideart]

#∞: Everyalways

When a Singularitime and an Entrospace learn to work together, they can stand on each other, allowing them to walk anywhere as long as their footsteps are in sync. Turns out neither of them react to the planet's gravity, they are exclusively attracted to the matter of each other. Once a pair figures this out, they make their way out of the planet's atmosphere towards an unknown location in deep space.

Turns out Singularitimes were the fragments of the avatar of Life and Everything That Has Been, while Entrospaces were the fragments of the avatar of Entropy, and The Nothingness That Will Be. Their constant struggle, eternally pushing into each other is what allows the universe to keep existing

Helping every single pair of Singularitimes & Entrospaces get back to space will allow this cosmic being to be whole once more. Everyalways.

Inspiration: Entropy will eventually make all life cease, but without it, Life would be impossible, our cells create order with the sodium-potassium pump, to then open the cell membrane to let entropy do its thing and balance the ions, like a waterfall, this rapid influx powers ATPase like a generator, which creates ATP, Life utilizes Entropy to power itself. In turn, lifeforms increase the heat of any given system, meaning Entropy grows when Life is present. As such, these two forces, Order & Chaos in constant struggle, is what allows our universe to exist as is. So together, they are everything ever.

#creature design #species design #singularity #entropy #cosmos #alien design #aliens #nimalings #Singularitime & Entrospace

[confusedfeelsfangirl]

Studying biology gives you access to some very specific and unsettling threats like « I will come to your house this evening and inactivate your Na/K ATPase channels » or « Don’t make me confiscate your dendritic cells »

#confusedfeelsfangirl rambles #biology #I’m studying for an immunology exam rn and I want to cry #why is our immune system so complex

[heartlaboratory]

Exercise seems to change the potassium concentration far beyond the normal limits seen in resting subjects, a state known as hypokalemia. Common manifestations of this condition are muscle weakness, spasms and cramps; tinglings, numbness and confusion; extreme tiredness and fatigue. The most dangerous effects target the victim’s heart though in the form of arrhythmias (considering that the heart is technically a muscle). Recent experimental studies have suggested that hypokalemia-induced arrhythmias are initiated by the reduced activity of the Na+/K+-ATPase (a pump that exchanges sodium and potassium between the itracellular and the extracellular spaces), subsequently leading to calcium overload, calcium-activated intracellular processes, and development of afterdepolarizations; The electrophysiological changes iduced by these events are very complex but they can be summarized with the fact that a premature beat, for some areas in the heart, becomes more probable thus inducing ventricular arrhythmias. This condition can get worse with the generation of localized and alternative electric circuits. Given this the most common heart rhythm alterations in the case of hypokalemia are tachycardia, premature beats, ventricular tachycardia and finally ventricular fibrillation. Hypokalemia rapidly induces heart rhythm changes but fortunately it is quite rare after the solely physical exercise, some people though can be predisposed (like with a pre existing heart conditions) or they can be in a predisposing condition (like after extreme sweating) and have to be considered at risk.

#cardiophile #cardiophilia #heartbeat #heartfetish #female heartbeat

[do-foryou]

Amiclear Review - Does Amiclear Really Work? – CAUTION - Amiclear Review...

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#youtube

[r-sensei]

ATP合成酵素回転の様子。

#ATPase

[whats-in-a-sentence]

A regulatory protein termed 14-3-3 protein has been found to bind to the phosphorylated C terminus of the guard cell H+-ATPase, but not to the nonphosphorylated one (see Figure 16.25).

"Plant Physiology and Development" int'l 6e - Taiz, L., Zeiger, E., Møller, I.M., Murphy, A.

#book quotes #plant physiology and development #nonfiction #textbook #regulatory protein #14 3 3 protein #phosphorylation #c terminus #guard cells #atpase #plant cells #plasma membrane #cytoplasm

[tenth-sentence]

Target proteins include transcription factors, various protein kinases, Ca²+-ATPases, enzymes producing reactive oxygen species (ROS), and ion channels.

"Plant Physiology and Development" int'l 6e - Taiz, L., Zeiger, E., Møller, I.M., Murphy, A.

#book quote #plant physiology and development #nonfiction #textbook #protein #target protein #transcription factor #kinase #protein kinase #calcium #cation #atpase #enzyme #reactive oxygen species #ros #ion channel

[mcatmemoranda]

There are multiple risk factors for the development of osteoporosis. These include but are not limited to advanced age, cigarette smoking, chronic glucocorticoid therapy, low body weight, previous fractures, history of rheumatoid arthritis, and excessive alcohol intake.

Antiepileptic drugs (AEDs) are associated with adverse effects on bone health. The AEDs most commonly associated with altered bone metabolism are those that induce the cytochrome P450 enzyme system. Specifically, the AED phenytoin has a direct inhibitory effect on intestinal calcium absorption and can stimulate osteoclastic bone resorption.

A score of less than -2.5 on DEXA scanning would indicate osteoporosis, a score of -1.0 to -2.5 would indicate osteopenia, and a score greater than -1.0 indicates normal bone density. Additionally, a fragility fracture (fracture from minor trauma such as a fall from a standing height or less) is diagnostic of osteoporosis without any further workup.

Bottom Line: The risk factors for osteoporosis include advanced age, cigarette smoking, chronic glucocorticoid therapy, physical inactivity, poor intake of calcium and vitamin D, body weight less than 127 lb, previous fractures, anticonvulsant use, hyperthyroidism, celiac disease, rheumatoid arthritis, and excessive alcohol intake.

The characteristic need for the child to use his hands to push himself to an upright position when arising from the floor is the Gower sign. It results from weakness in the proximal lower extremity muscles. Physical examination reveals pseudohypertrophy of the calf, lumbar lordosis, a waddling gait, shortening of the Achilles tendons, hypotonia, and hyporeflexia or areflexia. Patients usually use wheelchairs by age 12 or 13. Additional complications include delayed growth, dilated cardiomyopathy, increased fractures, progressive scoliosis with impaired pulmonary function, cognitive impairment, and eventual respiratory insufficiency.

Bottom Line: Elevated laboratory markers in the setting of Duchenne muscular dystrophy include serum creatine kinase, aspartate aminotransferase, and alanine transaminase.

COMBANK Insight: DMD is a progressive, myopathic disorder inherited in an X-linked, recessive fashion and caused by a defective gene on the X chromosome responsible for dystrophin production. Dystrophin normally serves to stabilize and prevent the breakdown of muscle fibers. Loss of dystrophin thus leads to muscle fiber degeneration, resulting in muscle weakness.

Wilson Disease, also known as hepatolenticular degeneration, is an autosomal recessive defect involving an ATPase, Cu2+ -transporting, β-polypeptide. In this disease state, copper is deposited in tissues of the brain, liver, kidneys, and Descemet membrane of the cornea (known as Kayser-Fleischer rings, which are seen in the exhibit). Parkinsonian-like tremor and dementia may be evident when the nervous system is affected. Renal tubular damage occurs in the kidneys and cirrhosis can develop in the liver. Diagnosis can be made with the observation of decreased serum ceruloplasmin. Treatment includes penicillamine, which creates a soluble complex with the metal that can be excreted through the urine.

Bottom Line: A Kayser-Fleischer ring is a golden brown ring observed in the Descemet layer of the cornea as a result of copper deposition and is seen in Wilson disease. Labs reveal low serum ceruloplasmin and treatment with penicillamine can stop the progression of this degenerative disease state.

The types of cancers that metastasize to the bone most commonly are lung, breast, thyroid, renal, and prostate. Multiple myeloma and lymphoma can both form lytic lesions from their origins within the marrow.

A SPEP and UPEP are sensitive for multiple myeloma and should be obtained along with a measurement of the patient's total protein and globulin levels.

Bottom Line: The initial workup of a new lytic lesion generally involves a CT chest/abdomen/pelvis, SPEP/UPEP, bone scan, basic labs, and mammogram or PSA

#osteoporosis #Duchenne muscular dystrophy #muscular dystrophy #Wilsons disease #multiple myeloma #cancer